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lncRNA: ENSG00000228623

Summary for ZNF883

Gene summary

Gene information	Ensembl ID	ENSG00000228623
	Gene symbol	ZNF883
	Gene name
	HGNC
	Entrez ID	169834
	Gene type	lincRNA
	Synonyms
	UniProtAcc

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Structure and expression level for ZNF883

AS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000228623	2.876822e+02	3.871407e+00	8.439945e-01	4.587005e+00	4.500000e-06	1.314230e-04	UP	PCPG
ENSG00000228623	1.578394e+02	1.410012e+00	2.345132e-01	6.012504e+00	1.830000e-09	6.160000e-09	UP	LUSC
ENSG00000228623	1.094255e+02	1.091115e+00	2.001116e-01	5.452533e+00	4.970000e-08	1.860000e-07	UP	LUAD

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID

Correlation

P-value

Cancer Type

Adjc.p-value

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lncRNA-Protein interaction for ZNF883

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000228623	ENST00000427548	ZNF883	ENSG00000184635	ZNF93	6.46	92.3941	P35789	TF	NA
ENSG00000228623	ENST00000427548	ZNF883	ENSG00000105750	ZNF85	5.55	93.3292	Q03923	TF	NA

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

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lncRNA-DNA interaction for ZNF883

lncRNA targets the enhancer region and positively regulates the gene expression.

Only predicted by TDF

GEMIN6,TEX10,BTF3L4,PRPF4,CEBPZ,NIP7,BRIX1,ZNF93,PRPF38A,TTF1,BBS10,SMC2,KLHL23,POGLUT1

Exist in public source

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for ZNF883

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

LncRNA Ensembl ID

LncRNA ENST ID

Exon ID

Skipped Exon

ndG

Gene name with skipped exon

TransID with skipped exon

ORF mutation

-lncRNA and exonskipping events are negatively correlated.

LncRNA Ensembl ID

LncRNA ENST ID

Exon ID

Skipped Exon

ndG

Gene name with skipped exon

TransID with skipped exon

LOF

lncRNA targets by miRNA.

LncRNA Ensembl ID

miRNA ID

LncRNA ENST ID

Binding site in lncRNA

Score

Energy

Align Len

Public source

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Variants for ZNF883

RNA A-to-I editing events in lncRNA.

LncRNAediting ID

LncRNA Ensembl ID

Chromosome

Editing Position

Strand

Gene Type

Gene Name

Transcript ID

Transcript Type

Transcript Name

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID

LncRNA Index

Cancer Type

Chr_Postion_Strand

AVE1

AVE2

log2FC

W-value

P-value

Adjc.p-value

Change

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID

LncRNA Index

Correlation

P-value

Adjc.p-value

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID	LncRNA Name	SNP info	Number of Positive corelated Cancer	Positive corelated Cancer	Number of Negative corelated Cancer	Negative corelated Cancer
ENSG00000228623	ZNF883	rs1324927:115744562:A:C:+	0		1	LGG
ENSG00000228623	ZNF883	rs10981573:115745518:A:G:+	1	LGG	0
ENSG00000228623	ZNF883	rs10981580:115745721:G:A	1	LGG	0
ENSG00000228623	ZNF883	rs10981579:115745706:T:A	1	LGG	0
ENSG00000228623	ZNF883	rs10981577:115745661:C:T	1	LGG	0
ENSG00000228623	ZNF883	rs10981578:115745662:C:A	1	LGG	0
ENSG00000228623	ZNF883	rs1324926:115744738:G:T	1	LGG	0
ENSG00000228623	ZNF883	rs2104391:115745240:C:T	1	LGG	0
ENSG00000228623	ZNF883	rs1408690:115745365:G:C	1	LGG	0
ENSG00000228623	ZNF883	rs2209408:115744313:A:G:+	0		1	LGG
ENSG00000228623	ZNF883	rs10981574:115745577:C:T	1	LGG	0
ENSG00000228623	ZNF883	rs10981575:115745589:C:T	1	LGG	0
ENSG00000228623	ZNF883	rs1324928:115744457:C:T	1	LGG	0
ENSG00000228623	ZNF883	rs10981594:115765026:G:A	1	LGG	0
ENSG00000228623	ZNF883	rs6477977:115765847:A:G	1	LGG	0
ENSG00000228623	ZNF883	rs2147652:115742912:A:T	1	LGG	0
ENSG00000228623	ZNF883	rs151301833:115742007:C:G	1	LGG	0
ENSG00000228623	ZNF883	rs141936987:115742174:C:A	1	LGG	0
ENSG00000228623	ZNF883	rs4978528:115742789:T:A	1	LGG	0
ENSG00000228623	ZNF883	rs12376293:115743235:C:T	1	LGG	0
ENSG00000228623	ZNF883	rs1324929:115744451:A:G	1	LGG	0
ENSG00000228623	ZNF883	rs7042589:115749992:C:A	1	LGG	0
ENSG00000228623	ZNF883	rs10513175:115746870:A:G:-	0		1	LGG
ENSG00000228623	ZNF883	rs1157984:115746536:T:C	1	LGG	0
ENSG00000228623	ZNF883	rs10981592:115764347:C:A	1	LGG	0
ENSG00000228623	ZNF883	rs149605257:115743800:G:A	1	LGG	0
ENSG00000228623	ZNF883	rs117842691:115743808:G:A	1	LGG	0
ENSG00000228623	ZNF883	rs10739382:115746977:C:T:-	1	LGG	0
ENSG00000228623	ZNF883	rs60471678:115753756:C:A	1	LGG	0
ENSG00000228623	ZNF883	rs112790745:115753765:AAG:A	1	LGG	0
ENSG00000228623	ZNF883	rs137866897:115753755:G:GA	1	LGG	0
ENSG00000228623	ZNF883	rs138278772:115743764:A:G	1	LGG	0
ENSG00000228623	ZNF883	rs10981567:115738996:T:C	1	LGG	0
ENSG00000228623	ZNF883	rs7019807:115748302:T:C	1	LGG	0
ENSG00000228623	ZNF883	rs7034589:115748333:G:A	1	LGG	0
ENSG00000228623	ZNF883	rs1886525:115739199:A:C	1	LGG	0
ENSG00000228623	ZNF883	rs1324937:115739318:G:A	1	LGG	0
ENSG00000228623	ZNF883	rs35472505:115740074:GA:G	1	LGG	0
ENSG00000228623	ZNF883	rs10981566:115738949:G:A	1	LGG	0
ENSG00000228623	ZNF883	rs1324954:115746828:G:A	1	LGG	0
ENSG00000228623	ZNF883	rs2093999:115753454:G:A	1	LGG	0
ENSG00000228623	ZNF883	rs11971:115760610:T:A	1	LGG	0
ENSG00000228623	ZNF883	rs112818054:115779507:C:T	1	LGG	0
ENSG00000228623	ZNF883	rs2418246:115781111:A:G:-	0		1	LGG
ENSG00000228623	ZNF883	rs12555877:115783310:A:T	1	LGG	0
ENSG00000228623	ZNF883	rs2182047:115775423:T:C	1	LGG	0
ENSG00000228623	ZNF883	rs2900562:115781408:G:A	1	LGG	0

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID

PC Gene ID

PC Gene Name

Positive correlated cancers

Cancer with PC gene up-regulation

Cancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID

LncRNA ENST ID

PC Gene Name

PC Gene ID

PC ENST ID

nDG

Cancer with PC gene up-regulation

Cancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000228623.3	ENST00000619044.1	44	195	61
ENSG00000228623.3	ENST00000427548.1	381	908	2050

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential