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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000228262

Summary for LINC01320

check button Gene summary

Gene informationEnsembl ID

ENSG00000228262

Gene symbol

LINC01320

Gene namelong intergenic non-protein coding RNA 1320
HGNC

50526

Entrez ID

104355288

Gene typelincRNA
Synonyms02p22.3|LINC01320
UniProtAcc

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Structure and expression level for LINC01320

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002282625.044596e+031.295726e+001.414978e-019.157216e+005.330000e-203.210000e-19UPKIRC
ENSG000002282625.839295e+02-4.422768e+005.045977e-01-8.764938e+001.870000e-182.630000e-17DOWNKICH
ENSG000002282623.358245e+031.090699e+002.069060e-015.271468e+001.350000e-076.800000e-07UPKIRP

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG00000228262-6.689227e-017.809542e-13KICH2.622705e-11

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lncRNA-Protein interaction for LINC01320

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for LINC01320

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for LINC01320

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for LINC01320

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name
LncEditing_25765ENSG00000228262.7chr234681982+lincRNALINC01320ENST00000630686.1lincRNALINC01320-014
LncEditing_25897ENSG00000228262.7chr234682117+lincRNALINC01320ENST00000630686.1lincRNALINC01320-014
LncEditing_25990ENSG00000228262.7chr234722513+lincRNALINC01320ENST00000630686.1lincRNALINC01320-014
LncEditing_26003ENSG00000228262.7chr234722518+lincRNALINC01320ENST00000630686.1lincRNALINC01320-014
LncEditing_26026ENSG00000228262.7chr234722572+lincRNALINC01320ENST00000630686.1lincRNALINC01320-014
LncEditing_26046ENSG00000228262.7chr234722582+lincRNALINC01320ENST00000630686.1lincRNALINC01320-014
LncEditing_26056ENSG00000228262.7chr234722589+lincRNALINC01320ENST00000630686.1lincRNALINC01320-014
LncEditing_26066ENSG00000228262.7chr234722590+lincRNALINC01320ENST00000630686.1lincRNALINC01320-014

check buttonEdited-associated DElncRNAs in cancer.
Differentially expressed gene
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange
ENSG00000228262LncEditing_25765KIRCchr2_34681982_+3.552863e+012.262203e+011.535500e+007.010641e+002.372279e-123.899566e-12UP
ENSG00000228262LncEditing_25897KIRCchr2_34682117_+3.347289e+012.238149e+011.722099e+006.715829e+001.870001e-112.912811e-11UP
ENSG00000228262LncEditing_25990KIRCchr2_34722513_+2.543042e+011.944233e+012.581617e+004.647183e+003.364986e-064.125718e-06UP
ENSG00000228262LncEditing_26003KIRCchr2_34722518_+2.584695e+011.923900e+012.347638e+006.136369e+008.442882e-101.237290e-09UP
ENSG00000228262LncEditing_26046KIRCchr2_34722582_+2.545608e+011.580153e+011.453602e+005.770804e+007.889414e-091.108097e-08UP
ENSG00000228262LncEditing_25990KIRPchr2_34722513_+1.516072e+012.055756e+01-2.276187e+00-2.883991e+003.926694e-034.374902e-03DOWN
ENSG00000228262LncEditing_26026KIRPchr2_34722572_+2.613421e+011.695017e+011.600923e+003.150690e+001.628855e-031.889809e-03UP
ENSG00000228262LncEditing_26056KIRPchr2_34722589_+1.888608e+011.545769e+013.460229e+002.566506e+001.027288e-021.103652e-02UP

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value
ENSG00000228262LncEditing_25990-3.854719e-011.145212e-044.559833e-04
ENSG00000228262LncEditing_26046-4.179113e-012.776525e-051.882831e-04
ENSG00000228262LncEditing_26056-9.150167e-013.861207e-031.655488e-02
ENSG00000228262LncEditing_26066-7.194846e-012.888069e-024.091431e-02
ENSG00000228262LncEditing_25990-8.033915e-012.951985e-024.159615e-02
ENSG00000228262LncEditing_26026-3.068525e-014.534412e-024.583699e-02

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000228262.7ENST00000625995.1311049
ENSG00000228262.7ENST00000423663.414148560
ENSG00000228262.7ENST00000628407.110639979
ENSG00000228262.7ENST00000627935.181597352
ENSG00000228262.7ENST00000626008.182533781
ENSG00000228262.7ENST00000616475.38829731
ENSG00000228262.7ENST00000630686.180393635
ENSG00000228262.7ENST00000626688.182444692
ENSG00000228262.7ENST00000604250.26543240
ENSG00000228262.7ENST00000626601.182488736
ENSG00000228262.7ENST00000627270.1842532
ENSG00000228262.7ENST00000607437.379429668
ENSG00000228262.7ENST00000603129.46526265
ENSG00000228262.7ENST00000453774.179389628
ENSG00000228262.7ENST00000621006.159790969
ENSG00000228262.7ENST00000587085.161432617