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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000225032

Summary for RP11-228B15.4

check button Gene summary

Gene informationEnsembl ID

ENSG00000225032

Gene symbol

RP11-228B15.4

Gene name
HGNC
Entrez ID

102723566

Gene typeantisense
Synonyms
UniProtAcc

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Structure and expression level for RP11-228B15.4

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002250321.594614e+021.162202e+001.303783e-018.914076e+004.920000e-192.810000e-18UPKIRC
ENSG000002250327.574804e+01-1.389969e+001.798178e-01-7.729874e+001.080000e-141.100000e-13DOWNUCEC

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002250323.748102e-017.837447e-04ACC5.686976e-03
ENSG000002250325.772467e-013.307006e-05CHOL1.441304e-04
ENSG00000225032-3.140971e-016.606185e-15UCEC6.520391e-14

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lncRNA-Protein interaction for RP11-228B15.4

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000225032ENST00000439298RP11-228B15.4ENSG00000167978SRRM211.4394.4353Q9UQ35RBPNA

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lncRNA-DNA interaction for RP11-228B15.4

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RP11-228B15.4

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
AP2S1,ATP5PB,MRPL37,FTL,NOP10,PSMD8,SLC25A3,GLRX3,ATP5MC3,SDHB
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000225032ENST00000425991exon_skip_370518chr22:50247691-50247776-14.05-0.2989HDAC10ENST00000216271Frame-shift
ENSG00000225032ENST00000425991exon_skip_382458chr3:38131595-38131638-14.42-0.4972ACAA1ENST00000333167Frame-shift
ENSG00000225032ENST00000425991exon_skip_4796chr1:41007448-41007545-12.68-0.2438CTPS1ENST00000372616,ENST00000372621Frame-shift
ENSG00000225032ENST00000425991exon_skip_41841chr10:68756272-68756483-21.04-0.1012CCAR1ENST00000265872Frame-shift
ENSG00000225032ENST00000425991exon_skip_290158chr17:42953723-42953778-8.43-0.1833AARSD1ENST00000427569Frame-shift
ENSG00000225032ENST00000425991exon_skip_300663chr19:1425877-1425960-10.52-0.2843DAZAP1ENST00000233078Frame-shift
ENSG00000225032ENST00000425991exon_skip_302168chr19:10680345-10680443-13.28-0.1492ILF3ENST00000590261Frame-shift
ENSG00000225032ENST00000425991exon_skip_327748chr2:95410863-95411026-20.83-0.1398FAHD2AENST00000233379,ENST00000447036Frame-shift
ENSG00000225032ENST00000425991exon_skip_470226chr7:103307595-103307708-11.77-0.1509PMPCBENST00000249269Frame-shift

check buttonlncRNA targets by miRNA.
lncRNA targets by miRNA
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source
ENSG00000225032hsa-mir-1307ENST00000439298chr9:127817866-127818005247.00-122.79148NA
ENSG00000225032hsa-mir-1307ENST00000439298chr9:127816443-127816608237.00-134.35168NA
ENSG00000225032hsa-mir-1307ENST00000439298chr9:127817427-127817572235.00-146.86150NA
ENSG00000225032hsa-mir-1307ENST00000439298chr9:127816206-127816350231.00-134.41148NA
ENSG00000225032hsa-mir-1307ENST00000439298chr9:127816067-127816197227.00-107.62125NA
ENSG00000225032hsa-mir-1307ENST00000439298chr9:127817698-127817850221.00-129.72156NA
ENSG00000225032hsa-mir-1307ENST00000439298chr9:127816634-127816773220.00-140.46148NA
ENSG00000225032hsa-mir-1307ENST00000439298chr9:127817145-127817303214.00-140.39162NA
ENSG00000225032hsa-mir-1307ENST00000439298chr9:127817567-127817710201.00-123.89145NA
ENSG00000225032hsa-mir-1307ENST00000439298chr9:127816766-127816914192.00-147.50149NA
ENSG00000225032hsa-mir-1307ENST00000439298chr9:127816929-127817082173.00-142.78152NA
ENSG00000225032hsa-mir-1307ENST00000425991chr9:127818291-127818436232.00-144.47138NA
ENSG00000225032hsa-mir-1307ENST00000425991chr9:127818451-127818619229.00-147.80159NA
ENSG00000225032hsa-mir-1307ENST00000425991chr9:127818120-127818274209.00-146.26156NA

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Variants for RP11-228B15.4

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation
ENSG00000225032ENST00000439298AP2S1ENSG00000042753ENST00000352203-0.1356545UCEC-
ENSG00000225032ENST00000439298AP2S1ENSG00000042753ENST00000601498-0.1260883UCEC-
ENSG00000225032ENST00000439298AP2S1ENSG00000042753ENST00000599990-0.1260883UCEC-
ENSG00000225032ENST00000439298AP2S1ENSG00000042753ENST00000593442-0.1260883UCEC-
ENSG00000225032ENST00000439298AP2S1ENSG00000042753ENST00000263270-0.1411621UCEC-
ENSG00000225032ENST00000439298AP2S1ENSG00000042753ENST00000597020-0.1411626UCEC-
ENSG00000225032ENST00000439298NOP10ENSG00000182117ENST00000328848-0.1124582UCEC-
ENSG00000225032ENST00000439298NOP10ENSG00000182117ENST00000557912-0.1128588UCEC-
ENSG00000225032ENST00000425991AP2S1ENSG00000042753ENST00000352203-0.149415UCEC-
ENSG00000225032ENST00000425991AP2S1ENSG00000042753ENST00000601498-0.153337UCEC-
ENSG00000225032ENST00000425991AP2S1ENSG00000042753ENST00000599990-0.153337UCEC-
ENSG00000225032ENST00000425991AP2S1ENSG00000042753ENST00000593442-0.153337UCEC-
ENSG00000225032ENST00000425991AP2S1ENSG00000042753ENST00000263270-0.149546UCEC-
ENSG00000225032ENST00000425991AP2S1ENSG00000042753ENST00000597020-0.143951UCEC-
ENSG00000225032ENST00000425991NOP10ENSG00000182117ENST00000328848-0.1009147UCEC-

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000225032.4ENST00000439298.41173511
ENSG00000225032.4ENST00000425991.11955131100