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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000223552

Summary for CCR5AS

check button Gene summary

Gene informationEnsembl ID

ENSG00000223552

Gene symbol

CCR5AS

Gene nameCCR5 antisense RNA
HGNC

54398

Entrez ID
Gene typeantisense
Synonyms03p21.31|RP11-24F11.2|CCR5AS
UniProtAcc

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Structure and expression level for CCR5AS

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002235525.301987e+011.792107e+005.512695e-013.250873e+001.150513e-034.265866e-03UPGBM
ENSG000002235523.997428e+012.184435e+001.445357e-011.511346e+011.320000e-513.410000e-50UPKIRC
ENSG000002235529.446925e+013.965470e+004.295316e-019.232081e+002.650000e-204.450000e-19UPKICH
ENSG000002235524.691052e+011.171971e+003.661498e-013.200796e+001.370485e-037.339360e-03UPREAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002235524.952196e-018.069319e-07KICH2.322811e-06
ENSG000002235523.673044e-017.416773e-21KIRC6.675095e-20

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lncRNA-Protein interaction for CCR5AS

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for CCR5AS

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
CCR1,SAMHD1,FCER1G,SMCO4,CEBPA,SH3BGRL3,MYO1F,NAGK,ITGB2,CCR5,RAB20,ZMYND15,NPC2,APOBR,SELPLG,LILRB4,CD4,LILRB2,CD300C,FUCA1,TNFRSF1B,C1QB,SPI1,LRRC25,SNX20,HEXB,C1QC,ARHGAP27,ADA2,HCK,RENBP,PTAFR,SIGLEC7,FGR,BCL2A1,SIGLEC9,RBM47,CTSH,NAGA,TRPM2,TYROBP,FCGR3A,SLC7A7,PIK3R5,UNC93B1,SLC9A9,EFHD2,LAPTM5,CCRL2,ITGAL,PHF11,NFAM1,CXCL16,PPM1M,CLEC12A,CTSZ,EPSTI1,MVP,CLEC7A,C1QA,TLR1,B2M,ARRB2,FYB1,FPR1,RAP2B,CASP1,C3AR1,LAIR1,ADAP2,FBP1,CTSS,SIGLEC10
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for CCR5AS

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for CCR5AS

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation
ENSG00000223552ENSG00000121797CCRL2COAD,DLBC,ESCA,GBM,KICH,KIRC,LAML,LUAD,MESO,PAAD,READ,STADGBM,KICH,KIRC
ENSG00000223552ENSG00000000938FGRDLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000005844ITGALDLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000010610CD4DLBC,GBM,KIRC,LAML,LUAD,MESOGBM,KIRC
ENSG00000223552ENSG00000011600TYROBPDLBC,GBM,KIRC,LAML,LUAD,MESOGBM,KIRC
ENSG00000223552ENSG00000028137TNFRSF1BDLBC,ESCA,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000049860HEXBDLBC,ESCA,GBM,LAML,MESOGBM
ENSG00000223552ENSG00000082074FYB1DLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000101160CTSZDLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000101336HCKDLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000101347SAMHD1DLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000110876SELPLGDLBC,GBM,KIRC,LAML,MESOKIRC
ENSG00000223552ENSG00000119655NPC2DLBC,GBM,KIRC,LAML,MESOGBM
ENSG00000223552ENSG00000129450SIGLEC9DLBC,GBM,KIRC,LAML,LUAD,MESOGBM,KIRC
ENSG00000223552ENSG00000131042LILRB2DLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000133106EPSTI1DLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000137752CASP1DLBC,GBM,KIRC,LAML,LUAD,MESO,PAADGBM,KIRC
ENSG00000223552ENSG00000139832RAB20DLBC,ESCA,GBM,MESO,PAAD,READGBM
ENSG00000223552ENSG00000141480ARRB2DLBC,ESCA,GBM,KICH,KIRC,LAML,MESOKICH,KIRC
ENSG00000223552ENSG00000141497ZMYND15DLBC,ESCA,GBM,KIRC,MESOGBM,KIRC
ENSG00000223552ENSG00000141506PIK3R5DLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000142185TRPM2DLBC,ESCA,GBM,KIRC,MESOKIRC
ENSG00000223552ENSG00000142347MYO1FDLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000142512SIGLEC10DLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000142634EFHD2DLBC,ESCA,KIRC,LAML,PAADKIRC
ENSG00000223552ENSG00000142669SH3BGRL3DLBC,GBM,KIRC,LAML,PAAD,STADKIRC
ENSG00000223552ENSG00000155465SLC7A7DLBC,ESCA,GBM,LAML,PAADGBM
ENSG00000223552ENSG00000158869FCER1GDLBC,GBM,KIRC,LAML,LUAD,MESOGBM,KIRC
ENSG00000223552ENSG00000159189C1QCDLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000160255ITGB2DLBC,GBM,KIRC,LAML,LUAD,MESOGBM,KIRC
ENSG00000223552ENSG00000160791CCR5DLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000161921CXCL16DLBC,ESCA,GBM,KIRC,LAML,MESO,PAADGBM
ENSG00000223552ENSG00000163131CTSSDLBC,ESCA,GBM,KIRC,LAML,LUAD,MESO,PAADGBM,KIRC
ENSG00000223552ENSG00000163823CCR1DLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000165140FBP1DLBC,ESCA,GBM,LAML,PAADGBM
ENSG00000223552ENSG00000166002SMCO4DLBC,ESCA,GBM,LAML,MESO,PAADGBM
ENSG00000223552ENSG00000166710B2MDLBC,GBM,KIRC,LAML,LUAD,MESOGBM,KIRC
ENSG00000223552ENSG00000167208SNX20DLBC,GBM,KIRC,LUAD,MESOGBM,KIRC
ENSG00000223552ENSG00000167613LAIR1DLBC,GBM,KIRC,LUAD,MESOGBM,KIRC
ENSG00000223552ENSG00000167850CD300CDLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000169403PTAFRDLBC,GBM,KIRC,LAML,MESO,PAADGBM,KIRC
ENSG00000223552ENSG00000171051FPR1DLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000171860C3AR1DLBC,GBM,KIRC,LUAD,MESOGBM,KIRC
ENSG00000223552ENSG00000172243CLEC7ADLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000172322CLEC12ADLBC,KIRC,LAML,LUAD,MESOKIRC
ENSG00000223552ENSG00000173369C1QBDLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000173372C1QADLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000174125TLR1DLBC,GBM,KIRC,LAML,MESOGBM
ENSG00000223552ENSG00000175489LRRC25DLBC,GBM,LAML,LUAD,MESOGBM
ENSG00000223552ENSG00000181467RAP2BDLBC,GBM,KIRC,LAML,MESOKIRC
ENSG00000223552ENSG00000181804SLC9A9DLBC,GBM,KIRC,LAML,MESOKIRC
ENSG00000223552ENSG00000184060ADAP2DLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000184730APOBRDLBC,ESCA,KIRC,MESO,STADKIRC
ENSG00000223552ENSG00000186818LILRB4DLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000198951NAGADLBC,GBM,KIRC,LAML,MESOGBM
ENSG00000223552ENSG00000203747FCGR3ADLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000235568NFAM1DLBC,GBM,KIRC,LAML,MESOGBM,KIRC
ENSG00000223552ENSG00000110057UNC93B1ESCA,GBM,KIRC,LAML,STADGBM
ENSG00000223552ENSG00000179163FUCA1ESCA,GBM,LAML,MESO,PAADGBM
ENSG00000223552ENSG00000140379BCL2A1GBM,KIRC,LAML,LUAD,MESOGBM,KIRC
ENSG00000223552ENSG00000162511LAPTM5GBM,KIRC,LAML,LUAD,MESOGBM,KIRC

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000223552.1ENST00000451485.199657956