lncRNAfunc Logo

Home

Download

Statistics

Landscape

Help

Contact

Center for Computational Systems Medicine
leaf

lncRNA summary

leaf

lncRNA structure and expression level

leaf

lncRNA-Protein interaction

leaf

lncRNA-DNA interaction

leaf

lncRNA-RNA interaction

leaf

Variants in lncRNA

leaf

lncRNAs regulate the target genes through functioning as enhancers

leaf

lncRNAs regulate the target genes through recruiting transcript factors

leaf

lncRNAs regulate the alternative splicing events through interacting with splicing factor

leaf

lncRNAs regulate mRNA through targeting the 3'-UTR region

leaf

lncRNAs regulate mRNA by competing with miRNA

leaf

lncRNA coding potential

lncRNA: ENSG00000213888

Summary for LINC01521

check button Gene summary

Gene informationEnsembl ID

ENSG00000213888

Gene symbol

LINC01521

Gene namelong intergenic non-protein coding RNA 1521
HGNC

26029

Entrez ID
Gene typelincRNA
Synonyms22q12.2|LINC01521
UniProtAcc

Top

Structure and expression level for LINC01521

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002138889.641452e+01-1.353337e+003.215661e-01-4.208580e+002.570000e-051.485290e-04DOWNGBM
ENSG000002138881.013792e+021.186014e+001.519042e-017.807646e+005.830000e-152.840000e-14UPLUSC

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG00000213888-4.582779e-016.300483e-06KICH1.391285e-05

Top

lncRNA-Protein interaction for LINC01521

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000213888ENST00000614284LINC01521ENSG00000118058KMT2A24.5795.5065Q03164TF,EpiNA
ENSG00000213888ENST00000614284LINC01521ENSG00000187605TET320.3791.8571O43151TF,EpiPredict
ENSG00000213888ENST00000614284LINC01521ENSG00000171634BPTF18.3794.9689Q12830TF,EpiNA
ENSG00000213888ENST00000614284LINC01521ENSG00000116539ASH1L21.0993.4047Q9NR48TF,EpiNA

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000213888ENST00000614284LINC01521ENSG00000118058KMT2A24.5795.4503Q03164TF,EpiNA
ENSG00000213888ENST00000614284LINC01521ENSG00000100207TCF2022.9293.0301Q9UGU0TFNA
ENSG00000213888ENST00000614284LINC01521ENSG00000116539ASH1L21.0992.8892Q9NR48TF,EpiNA
ENSG00000213888ENST00000614284LINC01521ENSG00000187605TET320.3791.8638O43151TF,EpiPredict
ENSG00000213888ENST00000614284LINC01521ENSG00000171634BPTF18.3794.879Q12830TF,EpiNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000213888ENST00000614284LINC01521ENSG00000213079SCAF822.4992.8317Q9UPN6RBPNA

Top

lncRNA-DNA interaction for LINC01521

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
RFX7,SON,SP2,PUM1,MEX3B,TTF1,KLF12,SART3,DZIP3,MEX3A,SRCAP,KAT7,SUGP2,DDX42,MAZ,ZFP1,ADNP,ZNF70,NCBP1,TERF2,BAZ2A,KMT2A,ASH1L,SF3A1,ZBED4,SALL2,TFDP2,ADAT1,TET3,TCF20,ZBTB5,ZXDA,ZFR,PATZ1,DDX17,ZNF25
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.
Only predicted by TDF
ZNF70,ZFP1,AGO1,RFX7,GTF2I,DDX46,MAZ,NCBP1,FOXK2,DDX17,BPTF,DHX30,ADAT1,SF3A1
Exist in public source
NA

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

Top

lncRNA-RNA interaction for LINC01521

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
CEBPB
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

Top

Variants for LINC01521

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

Top

lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

Top

lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types
ENSG00000213888ENSG00000118058KMT2AENSG00000181827RFX75GBM,KICH,KIRP,LAML,LGG
ENSG00000213888ENSG00000171634BPTFENSG00000181827RFX76GBM,KICH,KIRP,LAML,LGG,LUSC
ENSG00000213888ENSG00000118058KMT2AENSG00000263001GTF2I5GBM,KICH,KIRP,LAML,LGG
ENSG00000213888ENSG00000171634BPTFENSG00000263001GTF2I6GBM,KICH,KIRP,LAML,LGG,LUSC
ENSG00000213888ENSG00000171634BPTFENSG00000141568FOXK25GBM,KICH,LAML,LGG,LUSC
ENSG00000213888ENSG00000118058KMT2AENSG00000171634BPTF5GBM,KICH,KIRP,LAML,LGG
ENSG00000213888ENSG00000187605TET3ENSG00000171634BPTF5GBM,KIRP,LGG,LUSC,OV

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

Top

lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

Top

lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

Top

lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

Top

lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000213888.3ENST00000504184.347253396
ENSG00000213888.3ENST00000614284.11831176625