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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000206417

Summary for H1-10-AS1

check button Gene summary

Gene informationEnsembl ID

ENSG00000206417

Gene symbol

H1-10-AS1

Gene nameH1-10 antisense RNA 1
HGNC

27953

Entrez ID
Gene typeantisense
SynonymsH1-10-AS1|03q21.3|H1FX-AS1
UniProtAcc

Q4G0G2


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Structure and expression level for H1-10-AS1

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002064171.663697e+021.742322e+003.848657e-014.527090e+005.980000e-063.380000e-05UPCHOL
ENSG000002064172.297401e+021.020078e+001.264394e-018.067725e+007.160000e-161.050000e-14UPPRAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002064174.986035e-014.904109e-04CHOL9.773355e-04

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lncRNA-Protein interaction for H1-10-AS1

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000206417ENST00000502789H1FX-AS1ENSG00000204227RING117.0793.2273Q06587EpiChIP-seq
ENSG00000206417ENST00000502789H1FX-AS1ENSG00000077463SIRT66.9290.4298Q8N6T7EpiChIP-seq

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000206417ENST00000502789H1FX-AS1ENSG00000167967E4F169.492.1005Q66K89TFNA
ENSG00000206417ENST00000502789H1FX-AS1ENSG00000130254SAFB267.1495.467Q14151TF,RBPPredict
ENSG00000206417ENST00000502789H1FX-AS1ENSG00000099326MZF155.3893.6813P28698TFChIP-seq
ENSG00000206417ENST00000502789H1FX-AS1ENSG00000147789ZNF736.9294.0226P17097TFNA
ENSG00000206417ENST00000502789H1FX-AS1ENSG00000256223ZNF1013.3892.9763P21506TFNA
ENSG00000206417ENST00000502789H1FX-AS1ENSG00000167766ZNF838.9892.9232P51522TFNA
ENSG00000206417ENST00000502789H1FX-AS1ENSG00000105717PBX48.3691.587Q9BYU1TFNA
ENSG00000206417ENST00000502789H1FX-AS1ENSG00000250571GLI45.7290.9877P10075TFNA
ENSG00000206417ENST00000383461H1FX-AS1ENSG00000167967E4F160.0591.5672Q66K89TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000206417ENST00000502789H1FX-AS1ENSG00000130254SAFB267.1495.4051Q14151TF,RBPPredict
ENSG00000206417ENST00000502789H1FX-AS1ENSG00000004534RBM666.8795.1533P78332RBPPredict
ENSG00000206417ENST00000502789H1FX-AS1ENSG00000099622CIRBP21.0991.6174Q14011RBPNA
ENSG00000206417ENST00000502789H1FX-AS1ENSG00000125970RALY6.6293.9144Q9UKM9RBPNA

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lncRNA-DNA interaction for H1-10-AS1

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for H1-10-AS1

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
CNOT1,IDH3A,TUBA1B,PNPO,UHRF1BP1L,MYH9,OXSR1,BECN1,HIPK1,RNF40,SNX6,SCP2,NRBF2,ACTR3,TRIP11,SCYL2,PLEKHB2,BZW1,GORASP2,PSMC1,SEC24B,CLTC,NCOA1,MRPL19,ATP2A2,GCLM,SH3GLB1,LZIC,LIMA1,LRRC59,CCDC47,BCL2L13,SNX19,M6PR,SEC24D,IQGAP1,GTF2H3,SLMAP,EEA1,CLIP1,STAT3,SEC23A,STK24,SRP54,LUZP1,MAPK1,EIF3J,SMAD1,CNIH1,AGFG1,SEC22B,BRCC3,USP9X,NIPA2,TANGO6,DYNC1LI2,FOXN3,NPTN,DNAJC3,WDR7,RP2,NCOA4,KPNA3,BCL9L,EPS15,ACTR2,VAMP7,TFIP11,TNPO1,SEC23B,PPP2R5C,KIF2A,CSNK1A1,TMOD3,CAB39,TTC37,RANBP2,SEC31A,GOLM2,ABCE1,ARL2BP,USP8,DPP8,CPSF2,ARCN1,NEMF,MCFD2,SDAD1
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000206417ENST00000502789exon_skip_382458chr3:38131595-38131638-7.73-0.1933ACAA1ENST00000333167Frame-shift
ENSG00000206417ENST00000502789exon_skip_470226chr7:103307595-103307708-12.85-0.1260PMPCBENST00000249269Frame-shift

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for H1-10-AS1

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation
ENSG00000206417ENST00000511998CNIH1ENSG00000100528ENST00000556113-0.1217640-CHOL
ENSG00000206417ENST00000511998SEC23AENSG00000100934ENST00000557280-0.1863537-CHOL,PRAD
ENSG00000206417ENST00000511998SEC23AENSG00000100934ENST00000553970-0.1863537-CHOL,PRAD
ENSG00000206417ENST00000511998NRBF2ENSG00000148572ENST00000611479-0.11051-CHOL
ENSG00000206417ENST00000511998NCOA4ENSG00000266412ENST00000579039-0.1063284-CHOL
ENSG00000206417ENST00000511998PNPOENSG00000108439ENST00000584061-0.1081251-CHOL
ENSG00000206417ENST00000433902CNIH1ENSG00000100528ENST00000556113-0.1010110-CHOL
ENSG00000206417ENST00000433902TANGO6ENSG00000103047ENST00000261778-0.15811-CHOL
ENSG00000206417ENST00000433902PNPOENSG00000108439ENST00000584061-0.15141-CHOL
ENSG00000206417ENST00000383461CNIH1ENSG00000100528ENST00000556113-0.1940989-CHOL
ENSG00000206417ENST00000383461SEC23AENSG00000100934ENST00000557280-0.19252276-CHOL,PRAD
ENSG00000206417ENST00000383461SEC23AENSG00000100934ENST00000553970-0.19252276-CHOL,PRAD
ENSG00000206417ENST00000383461NCOA4ENSG00000266412ENST00000579039-0.10181477-CHOL
ENSG00000206417ENST00000383461PNPOENSG00000108439ENST00000584061-0.12251255-CHOL
ENSG00000206417ENST00000383461PNPOENSG00000108439ENST00000583245-0.1055949-CHOL
ENSG00000206417ENST00000502789CNIH1ENSG00000100528ENST00000556113-0.1326516-CHOL
ENSG00000206417ENST00000502789SEC23AENSG00000100934ENST00000557280-0.1211471-CHOL,PRAD
ENSG00000206417ENST00000502789SEC23AENSG00000100934ENST00000553970-0.1211471-CHOL,PRAD
ENSG00000206417ENST00000502789NRBF2ENSG00000148572ENST00000611479-0.1036390-CHOL
ENSG00000206417ENST00000511998PNPOENSG00000108439ENST00000585320-0.13155-CHOL
ENSG00000206417ENST00000511998SCP2ENSG00000116171ENST00000430330-0.1007673-CHOL
ENSG00000206417ENST00000511998SEC24DENSG00000150961ENST00000506622-0.1151694-CHOL
ENSG00000206417ENST00000433902PNPOENSG00000108439ENST00000225573-0.19121-CHOL
ENSG00000206417ENST00000383461PNPOENSG00000108439ENST00000585320-0.14481282-CHOL
ENSG00000206417ENST00000383461SEC24DENSG00000150961ENST00000506622-0.18821-CHOL
ENSG00000206417ENST00000502789PNPOENSG00000108439ENST00000225573-0.1698320-CHOL
ENSG00000206417ENST00000502789SCP2ENSG00000116171ENST00000478274-0.10961-CHOL
ENSG00000206417ENST00000511998SLMAPENSG00000163681ENST00000416658-0.15621-PRAD
ENSG00000206417ENST00000511998SLMAPENSG00000163681ENST00000495364-0.2148795-PRAD
ENSG00000206417ENST00000511998SLMAPENSG00000163681ENST00000494088-0.17671-PRAD
ENSG00000206417ENST00000433902SLMAPENSG00000163681ENST00000416658-0.14991-PRAD
ENSG00000206417ENST00000433902SLMAPENSG00000163681ENST00000495364-0.16651-PRAD
ENSG00000206417ENST00000433902SLMAPENSG00000163681ENST00000494088-0.14991-PRAD
ENSG00000206417ENST00000383461SLMAPENSG00000163681ENST00000416658-0.11561-PRAD
ENSG00000206417ENST00000383461SLMAPENSG00000163681ENST00000495364-0.24412054-PRAD
ENSG00000206417ENST00000383461SLMAPENSG00000163681ENST00000494088-0.13242028-PRAD
ENSG00000206417ENST00000502789SLMAPENSG00000163681ENST00000416658-0.1099212-PRAD
ENSG00000206417ENST00000502789SLMAPENSG00000163681ENST00000495364-0.2049117-PRAD
ENSG00000206417ENST00000502789SLMAPENSG00000163681ENST00000494088-0.1200285-PRAD

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000206417.7ENST00000511998.14751194
ENSG00000206417.7ENST00000433902.23039102
ENSG00000206417.7ENST00000383461.5110154483
ENSG00000206417.7ENST00000502789.21203612