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lncRNA: ENSG00000178977

Summary for LINC00324

Gene summary

Gene information	Ensembl ID	ENSG00000178977
	Gene symbol	LINC00324
	Gene name	long intergenic non-protein coding RNA 324
	HGNC	26628
	Entrez ID	284029
	Gene type	lincRNA
	Synonyms	17p13.1\|LINC00324
	UniProtAcc

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Structure and expression level for LINC00324

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000178977	1.175010e+02	1.326229e+00	3.724908e-01	3.560435e+00	3.702420e-04	1.572161e-03	UP	GBM
ENSG00000178977	1.225660e+02	-1.099271e+00	3.119931e-01	-3.523383e+00	4.260750e-04	1.616533e-03	DOWN	CHOL
ENSG00000178977	1.249661e+02	-1.295935e+00	1.665306e-01	-7.781962e+00	7.140000e-15	7.050000e-14	DOWN	KICH
ENSG00000178977	9.381057e+01	-1.005462e+00	1.370167e-01	-7.338243e+00	2.160000e-13	1.690000e-12	DOWN	COAD
ENSG00000178977	9.066202e+01	-1.076314e+00	2.755912e-01	-3.905471e+00	9.400000e-05	7.152680e-04	DOWN	READ

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID	Correlation	P-value	Cancer Type	Adjc.p-value
ENSG00000178977	-6.306975e-01	3.494434e-11	KICH	5.522576e-10

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lncRNA-Protein interaction for LINC00324

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000178977	ENST00000315707	LINC00324	ENSG00000067066	SP100	55.71	95.6625	P23497	TF,Epi	NA
ENSG00000178977	ENST00000315707	LINC00324	ENSG00000079263	SP140	41.59	95.4457	Q13342	TF,Epi	NA
ENSG00000178977	ENST00000315707	LINC00324	ENSG00000112511	PHF1	6.81	93.378	O43189	TF,Epi	NA
ENSG00000178977	ENST00000315707	LINC00324	ENSG00000066136	NFYC	15.78	92.1029	Q13952	TF,Epi	ChIP-seq

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000178977	ENST00000315707	LINC00324	ENSG00000067066	SP100	55.71	95.6517	P23497	TF,Epi	NA
ENSG00000178977	ENST00000315707	LINC00324	ENSG00000135899	SP110	52.19	95.0882	Q9HB58	TF	NA
ENSG00000178977	ENST00000315707	LINC00324	ENSG00000079263	SP140	41.59	95.4479	Q13342	TF,Epi	NA
ENSG00000178977	ENST00000315707	LINC00324	ENSG00000236287	ZBED5	40.79	91.8125	Q49AG3	TF	NA
ENSG00000178977	ENST00000315707	LINC00324	ENSG00000197857	ZNF44	34.12	95.4932	P15621	TF	NA
ENSG00000178977	ENST00000315707	LINC00324	ENSG00000169740	ZNF32	27.05	93.133	P17041	TF	NA
ENSG00000178977	ENST00000315707	LINC00324	ENSG00000065029	ZNF76	25.88	93.2379	P36508	TF	NA
ENSG00000178977	ENST00000315707	LINC00324	ENSG00000105708	ZNF14	22.89	94.4847	P17017	TF	NA
ENSG00000178977	ENST00000315707	LINC00324	ENSG00000154957	ZNF18	17.7	90.7589	P17022	TF	NA
ENSG00000178977	ENST00000315707	LINC00324	ENSG00000066136	NFYC	15.78	92.2765	Q13952	TF,Epi	ChIP-seq
ENSG00000178977	ENST00000315707	LINC00324	ENSG00000125347	IRF1	7.9	92.3709	P10914	TF	ChIP-seq
ENSG00000178977	ENST00000315707	LINC00324	ENSG00000112511	PHF1	6.81	93.4794	O43189	TF,Epi	NA
ENSG00000178977	ENST00000315707	LINC00324	ENSG00000126456	IRF3	3.84	92.6026	Q14653	TF	ChIP-seq

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000178977	ENST00000315707	LINC00324	ENSG00000100650	SRSF5	38.69	93.0094	Q13243	RBP	NA
ENSG00000178977	ENST00000315707	LINC00324	ENSG00000164548	TRA2A	33.3	91.8138	Q13595	RBP	ENCODE
ENSG00000178977	ENST00000315707	LINC00324	ENSG00000172795	DCP2	8.75	90.3885	Q8IU60	RBP	NA

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lncRNA-DNA interaction for LINC00324

lncRNA targets the enhancer region and positively regulates the gene expression.

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for LINC00324

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

Only predicted by lncTar

PA2G4,NOP2

Exist in public source

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

lncRNA and exonskipping events positive correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	ORF mutation
ENSG00000178977	ENST00000315707	exon_skip_75398	chr11:72692752-72692785	-14.61	-0.5218	ARAP1	ENST00000393605	In-frame
ENSG00000178977	ENST00000315707	exon_skip_482144	chr8:22539468-22539498	-8.68	-0.4133	PPP3CC	ENST00000240139	In-frame

-lncRNA and exonskipping events are negatively correlated.

lncRNA and exonskipping events negative correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	LOF
ENSG00000178977	ENST00000315707	exon_skip_95025	chr12:79805591-79805768	-15.83	-0.1070	PPP1R12A	ENST00000261207,ENST00000450142	In-frame
ENSG00000178977	ENST00000315707	exon_skip_482403	chr8:27445793-27445919	-16.36	-0.1620	PTK2B	ENST00000346049,ENST00000397501	In-frame

lncRNA targets by miRNA.

LncRNA Ensembl ID

miRNA ID

LncRNA ENST ID

Binding site in lncRNA

Score

Energy

Align Len

Public source

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Variants for LINC00324

RNA A-to-I editing events in lncRNA.

LncRNAediting ID

LncRNA Ensembl ID

Chromosome

Editing Position

Strand

Gene Type

Gene Name

Transcript ID

Transcript Type

Transcript Name

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID

LncRNA Index

Cancer Type

Chr_Postion_Strand

AVE1

AVE2

log2FC

W-value

P-value

Adjc.p-value

Change

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID

LncRNA Index

Correlation

P-value

Adjc.p-value

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID

PC Gene ID

PC Gene Name

Positive correlated cancers

Cancer with PC gene up-regulation

Cancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID

LncRNA ENST ID

PC Gene Name

PC Gene ID

PC ENST ID

nDG

Cancer with PC gene up-regulation

Cancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000178977.3	ENST00000315707.3	131	38	433

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential