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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000177335

Summary for LINC02904

check button Gene summary

Gene informationEnsembl ID

ENSG00000177335

Gene symbol

LINC02904

Gene namelong intergenic non-protein coding RNA 2904
HGNC

26731

Entrez ID

286122

Gene typeprocessed_transcript
Synonyms08q24.3|LINC02904|C8orf31
UniProtAcc

Q8N9H6


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Structure and expression level for LINC02904

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000001773351.682461e+021.503574e+004.154712e-013.618960e+002.957890e-041.344110e-03UPBLCA
ENSG000001773353.116162e+022.842396e+003.101108e-019.165745e+004.920000e-203.420000e-18UPSTAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value

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lncRNA-Protein interaction for LINC02904

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for LINC02904

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
USP43,LY6E
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for LINC02904

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for LINC02904

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name
LncEditing_216331ENSG00000177335.9chr8143050391+processed_transcriptC8orf31ENST00000524181.4lincRNAC8orf31-002

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value
ENSG00000177335LncEditing_2163315.349968e-013.988298e-024.639433e-02

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer
ENSG00000177335C8orf31rs7002986:144122357:G:A1THCA0
ENSG00000177335C8orf31rs11136300:144124609:T:C1THCA0
ENSG00000177335C8orf31rs6997455:144125727:T:A1THCA0
ENSG00000177335C8orf31rs12677840:144130430:C:G1THCA0
ENSG00000177335C8orf31rs7829801:144133433:C:T1THCA0
ENSG00000177335C8orf31rs11136304:144128157:T:C1THCA0
ENSG00000177335C8orf31rs11774844:144133401:G:A1THCA0
ENSG00000177335C8orf31rs11994636:144128221:G:A1THCA0
ENSG00000177335C8orf31rs11990478:144128228:T:C1THCA0
ENSG00000177335C8orf31rs7015223:144132469:A:G:+1THCA0
ENSG00000177335C8orf31rs72695021:144127500:C:T1THCA0
ENSG00000177335C8orf31rs74567557:144128714:G:A1THCA0
ENSG00000177335C8orf31rs7829903:144192016:T:C1LGG0
ENSG00000177335C8orf31rs11985927:144187645:A:T1LGG0
ENSG00000177335C8orf31rs4305880:144188997:A:G1LGG0
ENSG00000177335C8orf31rs55985912:144185799:A:G1LGG0
ENSG00000177335C8orf31rs7816760:144184077:T:C1LGG0
ENSG00000177335C8orf31rs56090455:144178490:C:T1LGG0
ENSG00000177335C8orf31rs10104005:144174038:C:T1LGG0
ENSG00000177335C8orf31rs55947314:144177032:G:A1LGG0
ENSG00000177335C8orf31rs56102934:144177207:T:G1LGG0
ENSG00000177335C8orf31rs28715464:144178093:C:T1LGG0
ENSG00000177335C8orf31rs56280739:144170896:G:C1LGG0
ENSG00000177335C8orf31rs74307503:144180108:C:T1LGG0
ENSG00000177335C8orf31rs77627829:144179843:G:C1LGG0
ENSG00000177335C8orf31rs3922889:144174928:G:C1LGG0
ENSG00000177335C8orf31rs4286929:144181153:A:C1LGG0
ENSG00000177335C8orf31rs7822363:144178953:A:G1LGG0
ENSG00000177335C8orf31rs74992492:144179749:G:T1LGG0
ENSG00000177335C8orf31rs76745515:144179837:G:A1LGG0
ENSG00000177335C8orf31rs79126372:144179940:C:G1LGG0
ENSG00000177335C8orf31rs80279064:144190196:G:C1LGG0
ENSG00000177335C8orf31rs74386176:144179740:C:T1LGG0
ENSG00000177335C8orf31rs61573766:144164512:C:T1LGG0
ENSG00000177335C8orf31rs7836843:144158917:G:C1LGG0
ENSG00000177335C8orf31rs77365286:144160176:C:T1LGG0
ENSG00000177335C8orf31rs55951527:144182452:C:T1LGG0
ENSG00000177335C8orf31rs12677931:144201664:A:C:-01LGG
ENSG00000177335C8orf31rs77558610:144195889:C:G1LGG0

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation
ENSG00000177335ENSG00000160932LY6EBLCA,CESC,OV,PAAD,STAD,TGCT,UCECBLCA,STAD

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000177335.9ENST00000517653.4125238615
ENSG00000177335.9ENST00000523766.4195715128
ENSG00000177335.9ENST00000523099.48031876
ENSG00000177335.9ENST00000524181.411943576
ENSG00000177335.9ENST00000395172.415353776
ENSG00000177335.9ENST00000519775.216757875
ENSG00000177335.9ENST00000520786.2752262
ENSG00000177335.9ENST00000622366.31283841