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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000167117

Summary for LINC00483

check button Gene summary

Gene informationEnsembl ID

ENSG00000167117

Gene symbol

LINC00483

Gene name
HGNC
Entrez ID

55018

Gene typeprocessed_transcript
Synonyms
UniProtAcc

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Structure and expression level for LINC00483

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000001671174.557500e+02-1.673857e+001.793738e-01-9.331672e+001.040000e-201.460000e-19DOWNCOAD
ENSG000001671175.055389e+02-1.241279e+003.332415e-01-3.724864e+001.954210e-047.647410e-04DOWNSTAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value

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lncRNA-Protein interaction for LINC00483

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for LINC00483

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
PLS1
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for LINC00483

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for LINC00483

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name
LncEditing_331676ENSG00000167117.7chr1750761125-processed_transcriptLINC00483ENST00000300458.1retained_intronLINC00483-001
LncEditing_331678ENSG00000167117.7chr1750761132-processed_transcriptLINC00483ENST00000300458.1retained_intronLINC00483-001
LncEditing_331681ENSG00000167117.7chr1750761142-processed_transcriptLINC00483ENST00000300458.1retained_intronLINC00483-001
LncEditing_331687ENSG00000167117.7chr1750761160-processed_transcriptLINC00483ENST00000300458.1retained_intronLINC00483-001
LncEditing_331689ENSG00000167117.7chr1750761168-processed_transcriptLINC00483ENST00000300458.1retained_intronLINC00483-001
LncEditing_331698ENSG00000167117.7chr1750761203-processed_transcriptLINC00483ENST00000450727.4lincRNALINC00483-003
LncEditing_331700ENSG00000167117.7chr1750761207-processed_transcriptLINC00483ENST00000450727.4lincRNALINC00483-003
LncEditing_331702ENSG00000167117.7chr1750761210-processed_transcriptLINC00483ENST00000450727.4lincRNALINC00483-003
LncEditing_331704ENSG00000167117.7chr1750761211-processed_transcriptLINC00483ENST00000450727.4lincRNALINC00483-003
LncEditing_331706ENSG00000167117.7chr1750761212-processed_transcriptLINC00483ENST00000450727.4lincRNALINC00483-003
LncEditing_331708ENSG00000167117.7chr1750761213-processed_transcriptLINC00483ENST00000450727.4lincRNALINC00483-003
LncEditing_331712ENSG00000167117.7chr1750761216-processed_transcriptLINC00483ENST00000450727.4lincRNALINC00483-003
LncEditing_331746ENSG00000167117.7chr1750761275-processed_transcriptLINC00483ENST00000450727.4lincRNALINC00483-003
LncEditing_331748ENSG00000167117.7chr1750761280-processed_transcriptLINC00483ENST00000450727.4lincRNALINC00483-003
LncEditing_331752ENSG00000167117.7chr1750761290-processed_transcriptLINC00483ENST00000450727.4lincRNALINC00483-003
LncEditing_331756ENSG00000167117.7chr1750761299-processed_transcriptLINC00483ENST00000450727.4lincRNALINC00483-003
LncEditing_331758ENSG00000167117.7chr1750761303-processed_transcriptLINC00483ENST00000450727.4lincRNALINC00483-003
LncEditing_331766ENSG00000167117.7chr1750761320-processed_transcriptLINC00483ENST00000450727.4lincRNALINC00483-003

check buttonEdited-associated DElncRNAs in cancer.
Differentially expressed gene
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange
ENSG00000167117LncEditing_331681COADchr17_50761142_-5.329664e+002.864303e+001.116245e+009.175150e+004.509477e-201.574621e-19UP
ENSG00000167117LncEditing_331687COADchr17_50761160_-4.536091e+002.166393e+009.379504e-011.209662e+011.100545e-331.803200e-32UP
ENSG00000167117LncEditing_331689COADchr17_50761168_-4.485396e+001.968462e+008.416331e-011.305238e+016.159251e-391.639900e-37UP
ENSG00000167117LncEditing_331698COADchr17_50761203_-4.841764e+002.677184e+001.169842e+009.958922e+002.305480e-231.271502e-22UP
ENSG00000167117LncEditing_331700COADchr17_50761207_-4.984848e+002.717101e+001.142228e+009.698302e+003.065576e-221.451039e-21UP
ENSG00000167117LncEditing_331704COADchr17_50761211_-4.930664e+002.951304e+001.350568e+007.359509e+001.845883e-133.780510e-13UP
ENSG00000167117LncEditing_331708COADchr17_50761213_-4.687208e+002.043030e+008.347119e-011.357528e+015.613074e-421.992641e-40UP
ENSG00000167117LncEditing_331712COADchr17_50761216_-4.863449e+002.514061e+001.050464e+001.130934e+011.179729e-291.478131e-28UP
ENSG00000167117LncEditing_331746COADchr17_50761275_-4.318384e+002.893005e+001.730335e+007.026072e+002.124296e-123.867308e-12UP
ENSG00000167117LncEditing_331748COADchr17_50761280_-4.182583e+001.834628e+008.411091e-011.219777e+013.194460e-346.185636e-33UP
ENSG00000167117LncEditing_331752COADchr17_50761290_-5.116752e+002.979207e+001.281559e+007.300901e+002.858477e-135.798625e-13UP
ENSG00000167117LncEditing_331758COADchr17_50761303_-4.450292e+002.557687e+001.251470e+009.837355e+007.772717e-234.138972e-22UP
ENSG00000167117LncEditing_331678READchr17_50761132_-5.196540e+003.166223e+001.399015e+003.403080e+006.663081e-048.186071e-04UP
ENSG00000167117LncEditing_331681READchr17_50761142_-5.299537e+002.831289e+001.105696e+005.677827e+001.364162e-084.888249e-08UP
ENSG00000167117LncEditing_331687READchr17_50761160_-4.361301e+002.273359e+001.063906e+006.939100e+003.946052e-123.992476e-11UP
ENSG00000167117LncEditing_331689READchr17_50761168_-4.218712e+002.142841e+001.023251e+007.025214e+002.137387e-122.297691e-11UP
ENSG00000167117LncEditing_331698READchr17_50761203_-4.857983e+002.774766e+001.237638e+006.197414e+005.739851e-102.903689e-09UP
ENSG00000167117LncEditing_331700READchr17_50761207_-5.202149e+002.643926e+001.024143e+006.698938e+002.099390e-111.569978e-10UP
ENSG00000167117LncEditing_331704READchr17_50761211_-4.749661e+003.066356e+001.584034e+003.936997e+008.250766e-051.252482e-04UP
ENSG00000167117LncEditing_331708READchr17_50761213_-4.404092e+002.200724e+009.991341e-017.669296e+001.729427e-143.963810e-13UP
ENSG00000167117LncEditing_331712READchr17_50761216_-4.754831e+002.539332e+001.105040e+006.404716e+001.506500e-108.935102e-10UP
ENSG00000167117LncEditing_331746READchr17_50761275_-4.297904e+002.998428e+001.925199e+003.935270e+008.310314e-051.252482e-04UP
ENSG00000167117LncEditing_331748READchr17_50761280_-4.102821e+001.726270e+008.006675e-017.629620e+002.354462e-144.499638e-13UP
ENSG00000167117LncEditing_331752READchr17_50761290_-5.030793e+003.009725e+001.349246e+004.472497e+007.731146e-061.399744e-05UP
ENSG00000167117LncEditing_331758READchr17_50761303_-4.430782e+002.586633e+001.287853e+005.609694e+002.026844e-086.577682e-08UP
ENSG00000167117LncEditing_331702STADchr17_50761210_-2.837321e+001.915303e+001.763804e+004.025702e+005.680549e-056.528528e-05UP
ENSG00000167117LncEditing_331704STADchr17_50761211_-3.375101e+001.541930e+008.848043e-018.450797e+002.893218e-179.065837e-17UP
ENSG00000167117LncEditing_331706STADchr17_50761212_-3.004776e+001.911119e+001.531770e+003.931249e+008.450567e-059.634723e-05UP
ENSG00000167117LncEditing_331746STADchr17_50761275_-3.162911e+001.463107e+008.991047e-018.896413e+005.768059e-192.238444e-18UP
ENSG00000167117LncEditing_331756STADchr17_50761299_-2.982347e+001.802091e+001.375939e+005.293200e+001.201945e-071.586346e-07UP
ENSG00000167117LncEditing_331766STADchr17_50761320_-2.601850e+001.942233e+002.370672e+003.888289e+001.009536e-041.143740e-04UP

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value
ENSG00000167117LncEditing_331746-4.048776e-015.801406e-039.427285e-03
ENSG00000167117LncEditing_331676-3.191255e-012.862782e-048.117261e-04
ENSG00000167117LncEditing_331702-4.100227e-017.757897e-039.642738e-03
ENSG00000167117LncEditing_331704-3.979014e-015.435956e-052.665129e-04
ENSG00000167117LncEditing_331706-4.319940e-018.513444e-031.032730e-02
ENSG00000167117LncEditing_331712-3.323917e-011.864051e-051.400021e-04
ENSG00000167117LncEditing_331746-3.652118e-013.531437e-052.077662e-04
ENSG00000167117LncEditing_331756-3.763364e-011.561702e-032.798380e-03
ENSG00000167117LncEditing_331766-3.968136e-019.272822e-031.109595e-02

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation
ENSG00000167117ENSG00000120756PLS1COAD,COAD,READ,READ,STAD,STADCOAD,COAD

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000167117.7ENST00000300458.11584480
ENSG00000167117.7ENST00000450727.417083595
ENSG00000167117.7ENST00000502517.4114152496
ENSG00000167117.7ENST00000419688.11013031
ENSG00000167117.7ENST00000576150.11063192