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Cancer Type: READ |
Summary for READ |
 Patient number summary of READ. |
| Cancer Type | Male Tumor Patients | Female Tumor Patients | Male Normal Patients | Female Normal Patients |
| READ | 91 | 75 | 3 | 7 |
| Result summary of READ. |
| Molecular | Sex-biased moleculars | Female-specific DEmoleculars | Male-specific DEmoleculars |
| ASevents | 1 | 379 | - |
| A-to-I editing | 38 | 1 | - |
| Coding Gene | 27 | 2924 | - |
| lncRNA | 1 | 166 | - |
| Methy | 2296 | - | - |
| miRNA | 1 | - | - |
| Protein | 40 | - | - |
| ∗Please click the number for more information. ∗For lncRNA and miRNA, Please click the download page for more detail. |
| Functional enrichment analysis of READ. |
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| Cancer Type | Term | Genes | Type | ||||
| READ | Cholesterol metabolism | APOA2;APOA1;APOC3 | Malebaised | ||||
| READ | PPAR signaling pathway | APOA2;APOA1;APOC3 | Malebaised | ||||
| READ | Vitamin digestion and absorption | APOA1 | Malebaised | ||||
| READ | African trypanosomiasis | APOA1 | Malebaised | ||||
| READ | Ferroptosis | CP | Malebaised | ||||
| READ | Fat digestion and absorption | APOA1 | Malebaised | ||||
| READ | Porphyrin and chlorophyll metabolism | CP | Malebaised | ||||
Top |
Sex-biased mutation in READ |
| Sex-biased mutation in READ. |
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Top |
TF-Gene regulation in READ |
| Top20 sex-biased TF-Gene regulation in READ. |
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| Table of top20 male-biased TF-Gene regulation in READ. |
| Cancer Type | Sex | Gene ID | TF | Gene Symbol | Score |
| READ | Male | ENSG00000175820 | ZNF418 | CCDC168 | 9.15617981206226 |
| READ | Male | ENSG00000188581 | ZNF418 | KRTAP1-1 | 8.26640864290562 |
| READ | Male | ENSG00000198680 | LHX2 | TUSC1 | 8.23243324078805 |
| READ | Male | ENSG00000111537 | ZNF418 | IFNG | 8.10470141215864 |
| READ | Male | ENSG00000125363 | ZNF418 | AMELX | 7.82545808351827 |
| READ | Male | ENSG00000112818 | ZNF431 | MEP1A | 7.4841401869514 |
| READ | Male | ENSG00000198680 | SOX8 | TUSC1 | 7.23551721008034 |
| READ | Male | ENSG00000253506 | HOXA9 | NACA2 | 7.19662875756727 |
| READ | Male | ENSG00000180660 | ZNF418 | MAB21L1 | 7.15233049268346 |
| READ | Male | ENSG00000196812 | ZNF418 | ZSCAN16 | 7.1479968645342 |
| READ | Male | ENSG00000180745 | HIC2 | CLRN3 | 7.10877634035261 |
| READ | Male | ENSG00000183542 | ZNF418 | KLRC4 | 7.05435052721711 |
| READ | Male | ENSG00000112818 | ZNF436 | MEP1A | 6.98699064952359 |
| READ | Male | ENSG00000198680 | ZNF45 | TUSC1 | 6.98559486663958 |
| READ | Male | ENSG00000253506 | ZNF354A | NACA2 | 6.88795334933065 |
| READ | Male | ENSG00000212916 | ZNF573 | MAP10 | 6.85592076999522 |
| READ | Male | ENSG00000253506 | MEIS1 | NACA2 | 6.84864160215034 |
| READ | Male | ENSG00000198225 | ZNF418 | FKBP1C | 6.78909195537976 |
| READ | Male | ENSG00000163380 | IRX5 | LMOD3 | 6.74656342271717 |
| READ | Male | ENSG00000205846 | ZNF235 | CLEC6A | 6.70715595538651 |
| ∗Please click the gene id for more information. |
| Table of top20 female-biased TF-Gene regulation in READ. |
| Cancer Type | Sex | Gene ID | TF | Gene Symbol | Score |
| READ | Female | ENSG00000187372 | PRDM6 | PCDHB13 | 7.55444786870506 |
| READ | Female | ENSG00000148483 | FOXP1 | TMEM236 | 7.53386694938173 |
| READ | Female | ENSG00000112175 | ZNF418 | BMP5 | 7.37889067504104 |
| READ | Female | ENSG00000001561 | ZNF35 | ENPP4 | 7.2926245558054 |
| READ | Female | ENSG00000148483 | SOX15 | TMEM236 | 7.27306607521175 |
| READ | Female | ENSG00000171860 | LHX8 | C3AR1 | 7.15025083125941 |
| READ | Female | ENSG00000001561 | NKX6-1 | ENPP4 | 7.11286508742051 |
| READ | Female | ENSG00000148483 | FOXD2 | TMEM236 | 7.02252622330574 |
| READ | Female | ENSG00000124429 | ONECUT3 | POF1B | 6.98434956917729 |
| READ | Female | ENSG00000181631 | ELF3 | P2RY13 | 6.94700146235585 |
| READ | Female | ENSG00000168497 | ZNF525 | CAVIN2 | 6.941632654601 |
| READ | Female | ENSG00000124429 | FOXP3 | POF1B | 6.94011391634669 |
| READ | Female | ENSG00000112175 | FOXC2 | BMP5 | 6.90601822972127 |
| READ | Female | ENSG00000127951 | DMRT2 | FGL2 | 6.90036203051747 |
| READ | Female | ENSG00000197629 | ZNF354A | MPEG1 | 6.89089281050627 |
| READ | Female | ENSG00000179144 | ZNF334 | GIMAP7 | 6.85848556921019 |
| READ | Female | ENSG00000197629 | NKX2-2 | MPEG1 | 6.85672018957358 |
| READ | Female | ENSG00000197629 | NKX3-2 | MPEG1 | 6.83660277571019 |
| READ | Female | ENSG00000124429 | POU3F3 | POF1B | 6.82684530304787 |
| READ | Female | ENSG00000169508 | ONECUT3 | GPR183 | 6.82155838063925 |
| ∗Please click the gene id for more information. |
Top |
RBP-ES regulation in READ |
| Top20 sex-biased RBP-ES regulation in READ. |
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| Table of top20 male-biased RBP-ES regulation in READ. |
| Cancer Type | Sex | Gene ID | RBP | ES | Score |
| READ | Male | ENSG00000099889 | ANKHD1 | exon_skip_367542 | 16.9362137479358 |
| READ | Male | ENSG00000113194 | STAR-PAP | exon_skip_439864 | 16.2009765308778 |
| READ | Male | ENSG00000120705 | STAR-PAP | exon_skip_444574 | 16.2009765308778 |
| READ | Male | ENSG00000196141 | MSI1 | exon_skip_332243 | 15.8217099970197 |
| READ | Male | ENSG00000026025 | MSI1 | exon_skip_39933 | 15.7587798747794 |
| READ | Male | ENSG00000131966 | DAZAP1 | exon_skip_106831 | 15.2009509537771 |
| READ | Male | ENSG00000127527 | RBM3 | exon_skip_316217 | 15.0453933555572 |
| READ | Male | ENSG00000172081 | ZNF638 | exon_skip_312762 | 15.0288453530592 |
| READ | Male | ENSG00000157500 | QKI | exon_skip_375535 | 15.0217152135572 |
| READ | Male | ENSG00000120451 | QKI | exon_skip_78662 | 15.0217152135572 |
| READ | Male | ENSG00000061794 | QKI | exon_skip_80932 | 15.0217152135572 |
| READ | Male | ENSG00000152942 | QKI | exon_skip_435311 | 15.0217152135571 |
| READ | Male | ENSG00000120438 | QKI | exon_skip_463216 | 15.0217152135571 |
| READ | Male | ENSG00000141380 | MSI1 | exon_skip_298573 | 14.9955709897095 |
| READ | Male | ENSG00000143337 | MSI1 | exon_skip_14448 | 14.9897132096793 |
| READ | Male | ENSG00000107815 | ANKHD1 | exon_skip_44429 | 14.9345108845202 |
| READ | Male | ENSG00000141959 | ANKHD1 | exon_skip_360611 | 14.9339142381668 |
| READ | Male | ENSG00000132680 | MSI1 | exon_skip_32717 | 14.9248176621598 |
| READ | Male | ENSG00000113163 | ANKHD1 | exon_skip_442698 | 14.9239995316355 |
| READ | Male | ENSG00000177169 | PPRC1 | exon_skip_88673 | 14.8785087085561 |
| ∗Please click the gene id for more information. |
| Table of top20 female-biased RBP-ES regulation in READ. |
| Cancer Type | Sex | Gene ID | RBP | ES | Score |
| READ | Female | ENSG00000130175 | ANKHD1 | exon_skip_302531 | 16.9344908999685 |
| READ | Female | ENSG00000100650 | STAR-PAP | exon_skip_107749 | 16.2103159670751 |
| READ | Female | ENSG00000103855 | STAR-PAP | exon_skip_123388 | 16.2103159670751 |
| READ | Female | ENSG00000167978 | STAR-PAP | exon_skip_132613 | 16.2103159670751 |
| READ | Female | ENSG00000124228 | STAR-PAP | exon_skip_352920 | 16.2103159670751 |
| READ | Female | ENSG00000089006 | STAR-PAP | exon_skip_355279 | 16.2103159670751 |
| READ | Female | ENSG00000131375 | STAR-PAP | exon_skip_372008 | 16.2103159670751 |
| READ | Female | ENSG00000104064 | MSI1 | exon_skip_127026 | 15.8577816689469 |
| READ | Female | ENSG00000171503 | MSI1 | exon_skip_426946 | 15.8540246232015 |
| READ | Female | ENSG00000144802 | MSI1 | exon_skip_376400 | 15.7414082605028 |
| READ | Female | ENSG00000133313 | MSI1 | exon_skip_297475 | 15.4931786657931 |
| READ | Female | ENSG00000047249 | MSI1 | exon_skip_489721 | 15.2564046472769 |
| READ | Female | ENSG00000187049 | DAZAP1 | exon_skip_59884 | 15.2058779436057 |
| READ | Female | ENSG00000135587 | DAZAP1 | exon_skip_453705 | 15.2058779436056 |
| READ | Female | ENSG00000122545 | DAZAP1 | exon_skip_465385 | 15.2058779436056 |
| READ | Female | ENSG00000106025 | DAZAP1 | exon_skip_479232 | 15.2058779436056 |
| READ | Female | ENSG00000119314 | DAZAP1 | exon_skip_505944 | 15.2058779436056 |
| READ | Female | ENSG00000177189 | DAZAP1 | exon_skip_514299 | 15.2058779436056 |
| READ | Female | ENSG00000090060 | RBM3 | exon_skip_109776 | 15.1141161864762 |
| READ | Female | ENSG00000169251 | RBM3 | exon_skip_379265 | 15.0968729856345 |
| ∗Please click the gene id for more information. |
Top |
eQTL regulation in READ |
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| Top Male-specific cis-sQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | SNP ID |
| ∗Please click the gene id for more information. |
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| Female-specific cis-eQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | SNP ID |
| ∗Please click the gene id for more information. |
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| Opposite sex-biased cis-eQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | SNP ID |
| ∗Please click the gene id for more information. |
Top |
sQTL regulation in READ |
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| Male-specific cis-sQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | SNP ID |
| ∗Please click the gene id for more information. |
|
| Female-specific cis-sQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | SNP ID |
| ∗Please click the gene id for more information. |
|
| Opposite sex-biased cis-sQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | SNP ID |
| ∗Please click the gene id for more information. |
Top |
eQTM regulation in READ |
|
| Male-specific cis-eQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | CpG ID |
| ∗Please click the gene id for more information. |
|
| Female-specific cis-eQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | CpG ID |
| ∗Please click the gene id for more information. |
|
| Opposite sex-biased cis-eQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | CpG ID |
| ∗Please click the gene id for more information. |
Top |
sQTM regulation in READ |
|
| Male-specific cis-sQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | CpG ID |
| ∗Please click the gene id for more information. |
|
| Female-specific cis-sQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | CpG ID |
| ∗Please click the gene id for more information. |
|
| Opposite sex-biased cis-sQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | CpG ID |
| ∗Please click the gene id for more information. |
