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Cancer Type: PCPG |
Summary for PCPG |
 Patient number summary of PCPG. |
| Cancer Type | Male Tumor Patients | Female Tumor Patients | Male Normal Patients | Female Normal Patients |
| PCPG | 81 | 102 | 2 | 1 |
| Result summary of PCPG. |
| Molecular | Sex-biased moleculars | Female-specific DEmoleculars | Male-specific DEmoleculars |
| ASevents | 1 | - | - |
| A-to-I editing | 97 | - | - |
| Coding Gene | 57 | - | - |
| lncRNA | 4 | - | - |
| Methy | 1525 | - | - |
| miRNA | 2 | - | - |
| Protein | 31 | - | - |
| ∗Please click the number for more information. ∗For lncRNA and miRNA, Please click the download page for more detail. |
| Functional enrichment analysis of PCPG. |
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| Cancer Type | Term | Genes | Type | ||||
| PCPG | Nitrogen metabolism | CA4;CA9 | Malebaised | ||||
| PCPG | Salivary secretion | CST1;NOS1;CST4 | Malebaised | ||||
| PCPG | Viral protein interaction with cytokine and cytokine receptor | IL6;CCL19;CXCL14 | Malebaised | ||||
| PCPG | Tryptophan metabolism | AOC1;TPH1 | Malebaised | ||||
| PCPG | Arginine and proline metabolism | AOC1;NOS1 | Malebaised | ||||
| PCPG | Legionellosis | IL6;HSPA6 | Malebaised | ||||
| PCPG | Cytokine-cytokine receptor interaction | IL6;CCL19;CXCL14 | Malebaised | ||||
| PCPG | Measles | IL6;HSPA6 | Malebaised | ||||
| PCPG | Histidine metabolism | AOC1 | Malebaised | ||||
| PCPG | Arginine biosynthesis | NOS1 | Malebaised | ||||
| PCPG | Proximal tubule bicarbonate reclamation | CA4 | Malebaised | ||||
| PCPG | Cortisol synthesis and secretion | NR5A1;HSD3B2;STAR;CYP21A2;CYP11A1;CYP17A1 | Femalebaised | ||||
| PCPG | Steroid hormone biosynthesis | HSD3B2;CYP21A2;CYP11B2;CYP11A1;CYP17A1 | Femalebaised | ||||
| PCPG | Cushing syndrome | NR5A1;HSD3B2;STAR;CYP21A2;CYP11A1;CYP17A1 | Femalebaised | ||||
| PCPG | Aldosterone synthesis and secretion | HSD3B2;STAR;CYP21A2;CYP11B2;CYP11A1 | Femalebaised | ||||
| PCPG | Ovarian steroidogenesis | HSD3B2;STAR;CYP11A1;CYP17A1 | Femalebaised | ||||
| PCPG | Cholesterol metabolism | STAR;APOC1 | Femalebaised | ||||
| PCPG | Fluid shear stress and atherosclerosis | NPPC;MGST1 | Femalebaised | ||||
| PCPG | Chemical carcinogenesis | MGST1;CACNA1A | Femalebaised | ||||
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Sex-biased mutation in PCPG |
| Sex-biased mutation in PCPG. |
Top |
TF-Gene regulation in PCPG |
| Top20 sex-biased TF-Gene regulation in PCPG. |
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| Table of top20 male-biased TF-Gene regulation in PCPG. |
| Cancer Type | Sex | Gene ID | TF | Gene Symbol | Score |
| PCPG | Male | ENSG00000198680 | LHX2 | TUSC1 | 8.72060096838313 |
| PCPG | Male | ENSG00000180745 | HOXC10 | CLRN3 | 8.07297316314404 |
| PCPG | Male | ENSG00000180745 | FOXK2 | CLRN3 | 8.06339111929853 |
| PCPG | Male | ENSG00000198680 | SOX8 | TUSC1 | 8.00746803790847 |
| PCPG | Male | ENSG00000175820 | ZNF418 | CCDC168 | 7.92303639966388 |
| PCPG | Male | ENSG00000125363 | FOXP3 | AMELX | 7.87938414866606 |
| PCPG | Male | ENSG00000262406 | FOXQ1 | MMP12 | 7.84942358500689 |
| PCPG | Male | ENSG00000180745 | CDX2 | CLRN3 | 7.81070506408046 |
| PCPG | Male | ENSG00000180745 | MEF2D | CLRN3 | 7.71574382790681 |
| PCPG | Male | ENSG00000175820 | NANOG | CCDC168 | 7.51646905101262 |
| PCPG | Male | ENSG00000180745 | ZNF25 | CLRN3 | 7.50926197455169 |
| PCPG | Male | ENSG00000125363 | SOX15 | AMELX | 7.48330344624061 |
| PCPG | Male | ENSG00000198680 | ZNF45 | TUSC1 | 7.40636707744146 |
| PCPG | Male | ENSG00000180745 | ZNF184 | CLRN3 | 7.28495458268483 |
| PCPG | Male | ENSG00000262406 | ZIM3 | MMP12 | 7.28016429449331 |
| PCPG | Male | ENSG00000148483 | SOX15 | TMEM236 | 7.23794148756861 |
| PCPG | Male | ENSG00000180745 | RFX5 | CLRN3 | 7.2171535397562 |
| PCPG | Male | ENSG00000174948 | IRF7 | GPR149 | 7.21196401349994 |
| PCPG | Male | ENSG00000174948 | POU1F1 | GPR149 | 7.15106519439795 |
| PCPG | Male | ENSG00000170542 | HMBOX1 | SERPINB9 | 7.03622342616558 |
| ∗Please click the gene id for more information. |
| Table of top20 female-biased TF-Gene regulation in PCPG. |
| Cancer Type | Sex | Gene ID | TF | Gene Symbol | Score |
| PCPG | Female | ENSG00000134042 | HOXD12 | MRO | 8.10124141676081 |
| PCPG | Female | ENSG00000256045 | HOXC10 | MTRNR2L10 | 7.77566302192157 |
| PCPG | Female | ENSG00000256045 | POU4F1 | MTRNR2L10 | 7.6717573132371 |
| PCPG | Female | ENSG00000198865 | ONECUT2 | CCDC152 | 7.54954623009195 |
| PCPG | Female | ENSG00000177932 | ZBTB20 | ZNF354C | 7.23414520804398 |
| PCPG | Female | ENSG00000180745 | HIC2 | CLRN3 | 6.98898673330191 |
| PCPG | Female | ENSG00000180745 | HNF4G | CLRN3 | 6.91789284620693 |
| PCPG | Female | ENSG00000025772 | HOXA6 | TOMM34 | 6.74776160407344 |
| PCPG | Female | ENSG00000204033 | FOXA2 | LRIT2 | 6.70216636965744 |
| PCPG | Female | ENSG00000143196 | ZNF85 | DPT | 6.69454744826772 |
| PCPG | Female | ENSG00000198680 | TFAP2A | TUSC1 | 6.69089621255461 |
| PCPG | Female | ENSG00000144647 | ZBTB33 | POMGNT2 | 6.68060523157604 |
| PCPG | Female | ENSG00000253506 | HOXA9 | NACA2 | 6.67521541680476 |
| PCPG | Female | ENSG00000057468 | NRF1 | MSH4 | 6.62438114271878 |
| PCPG | Female | ENSG00000198865 | TLX3 | CCDC152 | 6.62331407837607 |
| PCPG | Female | ENSG00000204033 | FOXD3 | LRIT2 | 6.58163742666539 |
| PCPG | Female | ENSG00000107014 | HMBOX1 | RLN2 | 6.50039106123662 |
| PCPG | Female | ENSG00000253506 | ZNF354A | NACA2 | 6.45565173454814 |
| PCPG | Female | ENSG00000182180 | ZFHX3 | MRPS16 | 6.43958455682676 |
| PCPG | Female | ENSG00000253506 | MEIS1 | NACA2 | 6.43629623339909 |
| ∗Please click the gene id for more information. |
Top |
RBP-ES regulation in PCPG |
| Top20 sex-biased RBP-ES regulation in PCPG. |
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| Table of top20 male-biased RBP-ES regulation in PCPG. |
| Cancer Type | Sex | Gene ID | RBP | ES | Score |
| PCPG | Male | ENSG00000141198 | QKI | exon_skip_154547 | 15.8102927808225 |
| PCPG | Male | ENSG00000008294 | QKI | exon_skip_291523 | 15.8102927808225 |
| PCPG | Male | ENSG00000038358 | ZNF638 | exon_skip_137869 | 15.066435222374 |
| PCPG | Male | ENSG00000157181 | ZNF638 | exon_skip_14904 | 15.066435222374 |
| PCPG | Male | ENSG00000111640 | ZNF638 | exon_skip_79513 | 15.066435222374 |
| PCPG | Male | ENSG00000169750 | ZNF638 | exon_skip_284588 | 15.0664352223739 |
| PCPG | Male | ENSG00000132680 | MSI1 | exon_skip_32717 | 14.9343232800723 |
| PCPG | Male | ENSG00000136045 | RBMS1 | exon_skip_86628 | 14.7945323825624 |
| PCPG | Male | ENSG00000092203 | RBMS1 | exon_skip_105123 | 14.7945323825623 |
| PCPG | Male | ENSG00000143569 | RBMS1 | exon_skip_10793 | 14.7945323825623 |
| PCPG | Male | ENSG00000160714 | RBMS1 | exon_skip_32047 | 14.7945323825623 |
| PCPG | Male | ENSG00000169189 | ANKHD1 | exon_skip_143308 | 14.7423177040704 |
| PCPG | Male | ENSG00000213923 | ANKHD1 | exon_skip_369450 | 14.6767194415281 |
| PCPG | Male | ENSG00000130520 | ANKHD1 | exon_skip_316424 | 14.671349390145 |
| PCPG | Male | ENSG00000108509 | STAR-PAP | exon_skip_285854 | 14.5297754525474 |
| PCPG | Male | ENSG00000138078 | MSI1 | exon_skip_338767 | 14.4842035656682 |
| PCPG | Male | ENSG00000184887 | YBX2 | exon_skip_110756 | 14.3401431895579 |
| PCPG | Male | ENSG00000171634 | YBX2 | exon_skip_155463 | 14.3401431895579 |
| PCPG | Male | ENSG00000135535 | YBX2 | exon_skip_461578 | 14.3401431895579 |
| PCPG | Male | ENSG00000065615 | RBM3 | exon_skip_453298 | 14.170737083007 |
| ∗Please click the gene id for more information. |
| Table of top20 female-biased RBP-ES regulation in PCPG. |
| Cancer Type | Sex | Gene ID | RBP | ES | Score |
| PCPG | Female | ENSG00000099889 | ANKHD1 | exon_skip_367542 | 16.7249939964634 |
| PCPG | Female | ENSG00000089006 | STAR-PAP | exon_skip_355279 | 16.5896299198819 |
| PCPG | Female | ENSG00000162441 | QKI | exon_skip_21707 | 15.8064940524543 |
| PCPG | Female | ENSG00000135587 | DAZAP1 | exon_skip_453705 | 15.6883119838043 |
| PCPG | Female | ENSG00000182718 | QKI | exon_skip_127786 | 15.3229857390297 |
| PCPG | Female | ENSG00000182179 | DAZAP1 | exon_skip_384361 | 15.1693449847631 |
| PCPG | Female | ENSG00000081721 | RBM3 | exon_skip_13441 | 15.1466750640052 |
| PCPG | Female | ENSG00000130332 | DAZAP1 | exon_skip_312846 | 15.1307971203063 |
| PCPG | Female | ENSG00000115414 | ZNF638 | exon_skip_346530 | 15.0634066890912 |
| PCPG | Female | ENSG00000157637 | ZNF638 | exon_skip_294349 | 15.0634066890911 |
| PCPG | Female | ENSG00000144674 | ZNF638 | exon_skip_372724 | 15.0634066890911 |
| PCPG | Female | ENSG00000104221 | ZNF638 | exon_skip_489144 | 15.0634066890911 |
| PCPG | Female | ENSG00000086712 | ZNF638 | exon_skip_509363 | 15.0634066890911 |
| PCPG | Female | ENSG00000141380 | MSI1 | exon_skip_298573 | 14.9964600444542 |
| PCPG | Female | ENSG00000134014 | MSI1 | exon_skip_482472 | 14.9728040773014 |
| PCPG | Female | ENSG00000057935 | RBMS1 | exon_skip_325099 | 14.7942080357629 |
| PCPG | Female | ENSG00000141959 | ANKHD1 | exon_skip_360611 | 14.7193275128817 |
| PCPG | Female | ENSG00000140859 | ANKHD1 | exon_skip_144760 | 14.6705260357325 |
| PCPG | Female | ENSG00000166479 | ZNF638 | exon_skip_299738 | 14.6292426504021 |
| PCPG | Female | ENSG00000106348 | STAR-PAP | exon_skip_479415 | 14.5863752572607 |
| ∗Please click the gene id for more information. |
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eQTL regulation in PCPG |
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| Top Male-specific cis-sQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | SNP ID |
| ∗Please click the gene id for more information. |
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| Female-specific cis-eQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | SNP ID |
| ∗Please click the gene id for more information. |
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| Opposite sex-biased cis-eQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | SNP ID |
| ∗Please click the gene id for more information. |
Top |
sQTL regulation in PCPG |
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| Male-specific cis-sQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | SNP ID |
| PCPG | ENSG00000072778 | ACADVL | exon_skip_148486 | rs10491084 |
| ∗Please click the gene id for more information. |
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| Female-specific cis-sQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | SNP ID |
| PCPG | ENSG00000128563 | PRKRIP1 | exon_skip_470072 | rs2950183 |
| ∗Please click the gene id for more information. |
|
| Opposite sex-biased cis-sQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | SNP ID |
| ∗Please click the gene id for more information. |
Top |
eQTM regulation in PCPG |
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| Male-specific cis-eQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | CpG ID |
| PCPG | ENSG00000135678 | cg12098645 |
| PCPG | ENSG00000095066 | cg19793697 |
| PCPG | ENSG00000168994 | cg24021113 |
| ∗Please click the gene id for more information. |
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| Female-specific cis-eQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | CpG ID |
| PCPG | ENSG00000012779 | cg09806262 |
| PCPG | ENSG00000175040 | cg17373442 |
| ∗Please click the gene id for more information. |
|
| Opposite sex-biased cis-eQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | CpG ID |
| ∗Please click the gene id for more information. |
Top |
sQTM regulation in PCPG |
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| Male-specific cis-sQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | CpG ID |
| PCPG | ENSG00000125089 | SH3TC1 | exon_skip_422557 | cg22079161 |
| ∗Please click the gene id for more information. |
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| Female-specific cis-sQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | CpG ID |
| PCPG | ENSG00000116691 | MIIP | exon_skip_1421 | cg02101693 |
| PCPG | ENSG00000130749 | ZC3H4 | exon_skip_319891 | cg12986110 |
| PCPG | ENSG00000115966 | ATF2 | exon_skip_345085 | cg14941291 |
| PCPG | ENSG00000088367 | EPB41L1 | exon_skip_351111 | cg01612936 |
| ∗Please click the gene id for more information. |
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| Opposite sex-biased cis-sQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | CpG ID |
| ∗Please click the gene id for more information. |
