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Center for Computational Systems Medicine
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Summary of cancer

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Sex-biased mutation in cancer

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Top 20 sex-biased TF-Gene regulation in cancer

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Top 20 sex-biased RBP-ES regulation in cancer

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Sex-biased cis-eQTL regulation in cancer

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Sex-biased cis-sQTL regulation in cancer

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Sex-biased cis-eQTM regulation in cancer

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Sex-biased cis-sQTM regulation in cancer

Cancer Type: MESO

Summary for MESO

check buttonPatient number summary of MESO.
Cancer TypeMale Tumor PatientsFemale Tumor PatientsMale Normal PatientsFemale Normal Patients
MESO711500

check buttonResult summary of MESO.
MolecularSex-biased molecularsFemale-specific DEmolecularsMale-specific DEmoleculars
ASevents

10

-

-

A-to-I editing

-

-

-

Coding Gene

125

-

-

lncRNA5--
Methy

1369

-

-

miRNA3--
Protein

10

-

-

∗Please click the number for more information.
∗For lncRNA and miRNA, Please click the download page for more detail.

check buttonFunctional enrichment analysis of MESO.
Functional enrichment analysis
Cancer TypeTermGenesType
MESORetinol metabolismSDR16C5;ADH1B;ADH1A;RDH16Malebaised
MESOIL-17 signaling pathwayCSF3;MMP1;MMP3Malebaised
MESOCytokine-cytokine receptor interactionTNFSF18;CSF3;TNFSF4;LEPR;IL20RBMalebaised
MESOTyrosine metabolismADH1B;ADH1AMalebaised
MESOBladder cancerMMP1;THBS1Malebaised
MESOFatty acid degradationADH1B;ADH1AMalebaised
MESOPyruvate metabolismADH1B;ADH1AMalebaised
MESOCoronavirus diseaseCSF3;MMP1;MMP3;RPS4Y1Malebaised
MESOMalariaCSF3;THBS1Malebaised
MESOCell adhesion moleculesNLGN4Y;CD274;PDCD1LG2Malebaised
MESOPhagosomeSFTPA2;SFTPA1;THBS1Malebaised
MESONeuroactive ligand-receptor interactionKISS1R;ADRA1B;GABRDFemalebaised
MESOPhagosomeCOMP;CD14Femalebaised

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Sex-biased mutation in MESO

check buttonSex-biased mutation in MESO.

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TF-Gene regulation in MESO

check buttonTop20 sex-biased TF-Gene regulation in MESO.
UCSC result

check buttonTable of top20 male-biased TF-Gene regulation in MESO.
Cancer TypeSexGene IDTFGene SymbolScore
MESOMale

ENSG00000256045

DMRT2MTRNR2L108.66179505151614
MESOMale

ENSG00000256045

ALX1MTRNR2L108.56481361082747
MESOMale

ENSG00000176907

ZSCAN23TCIM8.47978095973639
MESOMale

ENSG00000244067

ZNF211GSTA28.46322689629426
MESOMale

ENSG00000256045

HOXC10MTRNR2L108.26128659946444
MESOMale

ENSG00000253626

ZNF45EIF5AL17.94079228695079
MESOMale

ENSG00000143520

ZNF418FLG27.91777009464721
MESOMale

ENSG00000181631

CDC5LP2RY137.7674651134898
MESOMale

ENSG00000137440

PROP1FGFBP17.7518603969692
MESOMale

ENSG00000176907

SIX1TCIM7.72750296713698
MESOMale

ENSG00000176907

SOX4TCIM7.72293210470478
MESOMale

ENSG00000198865

ONECUT2CCDC1527.64150306272342
MESOMale

ENSG00000180745

FOXK2CLRN37.61031501198471
MESOMale

ENSG00000196126

IRX5HLA-DRB17.6096120799719
MESOMale

ENSG00000143520

ZNF879FLG27.60475095216012
MESOMale

ENSG00000176907

ZNF615TCIM7.57051724918152
MESOMale

ENSG00000148483

SOX15TMEM2367.51693838409581
MESOMale

ENSG00000244067

SOX5GSTA27.47185400059536
MESOMale

ENSG00000139780

OLIG1METTL21C7.46261889907006
MESOMale

ENSG00000148483

FOXD2TMEM2367.42057050271658
∗Please click the gene id for more information.

check buttonTable of top20 female-biased TF-Gene regulation in MESO.
Cancer TypeSexGene IDTFGene SymbolScore
MESOFemale

ENSG00000183269

ZNF35OR52E88.09063157538775
MESOFemale

ENSG00000180332

ZNF33BKCTD47.77568130208427
MESOFemale

ENSG00000183395

FOXA1PMCH7.5101082006723
MESOFemale

ENSG00000179144

ZNF334GIMAP77.39539188074818
MESOFemale

ENSG00000139675

IRF9HNRNPA1L27.38040195518111
MESOFemale

ENSG00000196812

IRF7ZSCAN167.35890957961515
MESOFemale

ENSG00000196812

EMX2ZSCAN167.25293705904148
MESOFemale

ENSG00000213886

SRYUBD7.21103914171293
MESOFemale

ENSG00000180332

ZNF418KCTD47.16411726952083
MESOFemale

ENSG00000103569

ZNF418AQP97.12062164978678
MESOFemale

ENSG00000179674

STAT2ARL147.05442867532254
MESOFemale

ENSG00000253537

ZNF25PCDHGA77.04084718587558
MESOFemale

ENSG00000253537

LMX1BPCDHGA76.98810915462138
MESOFemale

ENSG00000162630

ZNF175B3GALT26.98809175727342
MESOFemale

ENSG00000253537

FOXD3PCDHGA76.97711453169872
MESOFemale

ENSG00000162630

ZNF85B3GALT26.97278658335224
MESOFemale

ENSG00000169474

UNCXSPRR1A6.94688538735831
MESOFemale

ENSG00000139675

ZNF418HNRNPA1L26.94024245954736
MESOFemale

ENSG00000196812

MECOMZSCAN166.93038267297146
∗Please click the gene id for more information.

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RBP-ES regulation in MESO

check buttonTop20 sex-biased RBP-ES regulation in MESO.
UCSC result

check buttonTable of top20 male-biased RBP-ES regulation in MESO.
Cancer TypeSexGene IDRBPESScore
MESOMale

ENSG00000103855

STAR-PAPexon_skip_12338816.3881525825987
MESOMale

ENSG00000167978

STAR-PAPexon_skip_13261316.3881525825987
MESOMale

ENSG00000172932

STAR-PAPexon_skip_6174616.3881525825987
MESOMale

ENSG00000149547

QKIexon_skip_6634815.2027348180272
MESOMale

ENSG00000101596

QKIexon_skip_29534415.1847399068597
MESOMale

ENSG00000038219

QKIexon_skip_42857915.0985886678319
MESOMale

ENSG00000065615

RBM3exon_skip_45329814.4557834890295
MESOMale

ENSG00000072958

STAR-PAPexon_skip_30320214.3938465927007
MESOMale

ENSG00000177879

RBMS1exon_skip_43677614.294398674222
MESOMale

ENSG00000141429

RBM3exon_skip_29637113.9070320721988
MESOMale

ENSG00000057608

MSI1exon_skip_4751613.8061739163268
MESOMale

ENSG00000182973

QKIexon_skip_37245613.7043008886481
MESOMale

ENSG00000121741

DAZAP1exon_skip_9925613.4782167471089
MESOMale

ENSG00000196365

DAZAP1exon_skip_31352913.4548464814763
MESOMale

ENSG00000163541

SFPQexon_skip_34061313.3611935818759
MESOMale

ENSG00000167110

RBM3exon_skip_50742113.3348988429208
MESOMale

ENSG00000130703

ZCRB1exon_skip_35349013.1450139261249
MESOMale

ENSG00000102024

ZCRB1exon_skip_51203313.1450139261249
MESOMale

ENSG00000100612

QKIexon_skip_11372213.1142876924095
MESOMale

ENSG00000184254

ZNF638exon_skip_12534213.0632703594656
∗Please click the gene id for more information.

check buttonTable of top20 female-biased RBP-ES regulation in MESO.
Cancer TypeSexGene IDRBPESScore
MESOFemale

ENSG00000075884

MSI1exon_skip_33014517.5568123255868
MESOFemale

ENSG00000134057

MSI1exon_skip_43521917.5568123255868
MESOFemale

ENSG00000131508

MSI1exon_skip_43802017.5568123255868
MESOFemale

ENSG00000129925

ANKHD1exon_skip_14021416.4929592637407
MESOFemale

ENSG00000155380

ANKHD1exon_skip_2935716.4929592637407
MESOFemale

ENSG00000099889

ANKHD1exon_skip_36754216.4929592637407
MESOFemale

ENSG00000104368

ANKHD1exon_skip_48946816.4929592637407
MESOFemale

ENSG00000117593

STAR-PAPexon_skip_1423516.3856675085462
MESOFemale

ENSG00000136631

STAR-PAPexon_skip_964716.3856675085462
MESOFemale

ENSG00000100650

STAR-PAPexon_skip_10774916.3856675085461
MESOFemale

ENSG00000069966

STAR-PAPexon_skip_12716616.3856675085461
MESOFemale

ENSG00000113194

STAR-PAPexon_skip_43986416.3856675085461
MESOFemale

ENSG00000185246

QKIexon_skip_10632415.6789445867644
MESOFemale

ENSG00000174442

QKIexon_skip_12294115.6789445867644
MESOFemale

ENSG00000141198

QKIexon_skip_15454715.6789445867644
MESOFemale

ENSG00000162441

QKIexon_skip_2170715.6789445867644
MESOFemale

ENSG00000008294

QKIexon_skip_29152315.6789445867644
MESOFemale

ENSG00000151694

QKIexon_skip_33691415.6789445867644
MESOFemale

ENSG00000117153

QKIexon_skip_3548715.6789445867644
MESOFemale

ENSG00000171109

QKIexon_skip_37957615.6789445867644
∗Please click the gene id for more information.

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eQTL regulation in MESO

lncrna_protein
check buttonTop Male-specific cis-sQTM regulation (FDR <1e-5).
Cancer TypeGene IDGene NameSNP ID
∗Please click the gene id for more information.

lncrna_protein
check buttonFemale-specific cis-eQTL regulation (FDR <1e-5).
Cancer TypeGene IDGene NameSNP ID
∗Please click the gene id for more information.

lncrna_protein
check buttonOpposite sex-biased cis-eQTL regulation (FDR <1e-5).
Cancer TypeGene IDGene NameSNP ID
∗Please click the gene id for more information.

Top

sQTL regulation in MESO

lncrna_protein
check buttonMale-specific cis-sQTL regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDSNP ID
∗Please click the gene id for more information.

lncrna_protein
check buttonFemale-specific cis-sQTL regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDSNP ID
∗Please click the gene id for more information.

lncrna_protein
check buttonOpposite sex-biased cis-sQTL regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDSNP ID
∗Please click the gene id for more information.

Top

eQTM regulation in MESO

lncrna_protein
check buttonMale-specific cis-eQTM regulation (FDR <1e-5).
Cancer TypeGene IDCpG ID
∗Please click the gene id for more information.

lncrna_protein
check buttonFemale-specific cis-eQTM regulation (FDR <1e-5).
Cancer TypeGene IDCpG ID
∗Please click the gene id for more information.

lncrna_protein
check buttonOpposite sex-biased cis-eQTM regulation (FDR <1e-5).
Cancer TypeGene IDCpG ID
∗Please click the gene id for more information.

Top

sQTM regulation in MESO

lncrna_protein
check buttonMale-specific cis-sQTM regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDCpG ID
∗Please click the gene id for more information.

lncrna_protein
check buttonFemale-specific cis-sQTM regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDCpG ID
∗Please click the gene id for more information.

lncrna_protein
check buttonOpposite sex-biased cis-sQTM regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDCpG ID
∗Please click the gene id for more information.