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Cancer Type: LAML |
Summary for LAML |
 Patient number summary of LAML. |
| Cancer Type | Male Tumor Patients | Female Tumor Patients | Male Normal Patients | Female Normal Patients |
| LAML | 83 | 68 | 0 | 0 |
| Result summary of LAML. |
| Molecular | Sex-biased moleculars | Female-specific DEmoleculars | Male-specific DEmoleculars |
| ASevents | - | - | - |
| A-to-I editing | 101 | - | - |
| Coding Gene | 22 | - | - |
| lncRNA | 5 | - | - |
| Methy | 3403 | - | - |
| miRNA | 4 | - | - |
| Protein | - | - | - |
| ∗Please click the number for more information. ∗For lncRNA and miRNA, Please click the download page for more detail. |
| Functional enrichment analysis of LAML. |
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| Cancer Type | Term | Genes | Type | ||||
| LAML | Cocaine addiction | SLC18A2 | Malebaised | ||||
| LAML | Notch signaling pathway | TLE6 | Malebaised | ||||
| LAML | Nicotinate and nicotinamide metabolism | NT5E | Femalebaised | ||||
| LAML | Pyrimidine metabolism | NT5E | Femalebaised | ||||
| LAML | Leishmaniasis | FCGR3B | Femalebaised | ||||
| LAML | Staphylococcus aureus infection | FCGR3B | Femalebaised | ||||
| LAML | Fc gamma R-mediated phagocytosis | FCGR3B | Femalebaised | ||||
| LAML | Osteoclast differentiation | FCGR3B | Femalebaised | ||||
| LAML | Purine metabolism | NT5E | Femalebaised | ||||
| LAML | Natural killer cell mediated cytotoxicity | FCGR3B | Femalebaised | ||||
| LAML | Systemic lupus erythematosus | FCGR3B | Femalebaised | ||||
Top |
Sex-biased mutation in LAML |
| Sex-biased mutation in LAML. |
Top |
TF-Gene regulation in LAML |
| Top20 sex-biased TF-Gene regulation in LAML. |
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| Table of top20 male-biased TF-Gene regulation in LAML. |
| Cancer Type | Sex | Gene ID | TF | Gene Symbol | Score |
| LAML | Male | ENSG00000112175 | ZNF418 | BMP5 | 7.72608583756582 |
| LAML | Male | ENSG00000163285 | HOXA3 | GABRG1 | 7.7175264528979 |
| LAML | Male | ENSG00000120327 | ZNF418 | PCDHB14 | 7.49972718325414 |
| LAML | Male | ENSG00000146072 | LHX8 | TNFRSF21 | 7.41937018267794 |
| LAML | Male | ENSG00000166211 | ZNF334 | SPIC | 7.13589907779842 |
| LAML | Male | ENSG00000253953 | POU4F2 | PCDHGB4 | 7.11744997602462 |
| LAML | Male | ENSG00000081853 | ZNF354B | PCDHGA2 | 7.08509358473443 |
| LAML | Male | ENSG00000178662 | HOMEZ | CSRNP3 | 7.02480294090631 |
| LAML | Male | ENSG00000253953 | FOXF1 | PCDHGB4 | 7.01907433077083 |
| LAML | Male | ENSG00000154839 | HOXB9 | SKA1 | 6.91352505543462 |
| LAML | Male | ENSG00000253953 | FOXA3 | PCDHGB4 | 6.89014703318184 |
| LAML | Male | ENSG00000166211 | ZNF418 | SPIC | 6.8617835842589 |
| LAML | Male | ENSG00000081853 | SOX10 | PCDHGA2 | 6.83519716868389 |
| LAML | Male | ENSG00000253953 | ZNF85 | PCDHGB4 | 6.80508811064997 |
| LAML | Male | ENSG00000169213 | VSX2 | RAB3B | 6.78733837209789 |
| LAML | Male | ENSG00000253953 | NFAT5 | PCDHGB4 | 6.77686885506066 |
| LAML | Male | ENSG00000253953 | FOXA1 | PCDHGB4 | 6.71195194151669 |
| LAML | Male | ENSG00000143815 | NOBOX | LBR | 6.65958122571302 |
| LAML | Male | ENSG00000101082 | POU3F1 | SLA2 | 6.6108102575953 |
| LAML | Male | ENSG00000178662 | CUX2 | CSRNP3 | 6.60530742225462 |
| ∗Please click the gene id for more information. |
| Table of top20 female-biased TF-Gene regulation in LAML. |
| Cancer Type | Sex | Gene ID | TF | Gene Symbol | Score |
| LAML | Female | ENSG00000180332 | ZNF418 | KCTD4 | 8.97014308835097 |
| LAML | Female | ENSG00000089818 | HOXD10 | NECAP1 | 8.29378279260775 |
| LAML | Female | ENSG00000180332 | ZNF570 | KCTD4 | 8.08636746470192 |
| LAML | Female | ENSG00000175820 | ZNF235 | CCDC168 | 7.9825654263747 |
| LAML | Female | ENSG00000181963 | GATA5 | OR52K2 | 7.81375238064683 |
| LAML | Female | ENSG00000112232 | ZBTB22 | KHDRBS2 | 7.54792317366173 |
| LAML | Female | ENSG00000185899 | IRX2 | TAS2R60 | 7.51525509354197 |
| LAML | Female | ENSG00000169508 | LHX9 | GPR183 | 7.35682913761541 |
| LAML | Female | ENSG00000213203 | PBX4 | GIMAP1 | 7.35557079876652 |
| LAML | Female | ENSG00000260286 | ZNF354B | ARMH2 | 7.27200986021087 |
| LAML | Female | ENSG00000169508 | HESX1 | GPR183 | 7.24423373429861 |
| LAML | Female | ENSG00000188393 | HOXA6 | CLEC2A | 7.24393927698956 |
| LAML | Female | ENSG00000050438 | SOX12 | SLC4A8 | 7.22629563177015 |
| LAML | Female | ENSG00000169508 | SRF | GPR183 | 7.21512431904203 |
| LAML | Female | ENSG00000125900 | OLIG2 | SIRPD | 7.20545317618307 |
| LAML | Female | ENSG00000136866 | LHX8 | ZFP37 | 7.19128129299079 |
| LAML | Female | ENSG00000121933 | DMRTC2 | TMIGD3 | 7.11797222032423 |
| LAML | Female | ENSG00000089818 | HOXC9 | NECAP1 | 7.1156949648739 |
| LAML | Female | ENSG00000089818 | HOXD9 | NECAP1 | 7.11398465349354 |
| ∗Please click the gene id for more information. |
Top |
RBP-ES regulation in LAML |
| Top20 sex-biased RBP-ES regulation in LAML. |
| Table of top20 male-biased RBP-ES regulation in LAML. |
| Cancer Type | Sex | Gene ID | RBP | ES | Score |
| ∗Please click the gene id for more information. |
| Table of top20 female-biased RBP-ES regulation in LAML. |
| Cancer Type | Sex | Gene ID | RBP | ES | Score |
| ∗Please click the gene id for more information. |
Top |
eQTL regulation in LAML |
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| Top Male-specific cis-sQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | SNP ID |
| ∗Please click the gene id for more information. |
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| Female-specific cis-eQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | SNP ID |
| ∗Please click the gene id for more information. |
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| Opposite sex-biased cis-eQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | SNP ID |
| ∗Please click the gene id for more information. |
Top |
sQTL regulation in LAML |
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| Male-specific cis-sQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | SNP ID |
| ∗Please click the gene id for more information. |
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| Female-specific cis-sQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | SNP ID |
| ∗Please click the gene id for more information. |
|
| Opposite sex-biased cis-sQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | SNP ID |
| ∗Please click the gene id for more information. |
Top |
eQTM regulation in LAML |
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| Male-specific cis-eQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | CpG ID |
| LAML | ENSG00000007350 | cg26803301,cg15812025 |
| LAML | ENSG00000170689 | cg23245942,cg04917446,cg12057127,cg15117739 |
| LAML | ENSG00000170421 | cg21340733,cg03327403 |
| LAML | ENSG00000260027 | cg23245942,cg04917446,cg15117739 |
| LAML | ENSG00000160185 | cg20516845,cg09354050 |
| LAML | ENSG00000177455 | cg14102807,cg27565966 |
| LAML | ENSG00000172247 | cg15575356,cg27051260 |
| LAML | ENSG00000101188 | cg14871138,cg02216247 |
| LAML | ENSG00000078804 | cg16352321 |
| LAML | ENSG00000111412 | cg19850406,cg03109701 |
| LAML | ENSG00000131370 | cg02275418 |
| LAML | ENSG00000065320 | cg20123153 |
| LAML | ENSG00000171522 | cg11821200 |
| LAML | ENSG00000198589 | cg04551395 |
| LAML | ENSG00000169184 | cg00187327 |
| LAML | ENSG00000112053 | cg20132791,cg23807646 |
| LAML | ENSG00000185585 | cg05554161 |
| LAML | ENSG00000184058 | cg09781936 |
| LAML | ENSG00000008441 | cg04646674,cg13338734 |
| LAML | ENSG00000186010 | cg07624705 |
| LAML | ENSG00000171596 | cg22069247 |
| LAML | ENSG00000104447 | cg17131553 |
| LAML | ENSG00000128283 | cg15035133 |
| LAML | ENSG00000175505 | cg15365888 |
| LAML | ENSG00000113140 | cg27128761 |
| LAML | ENSG00000197283 | cg07417146 |
| LAML | ENSG00000262655 | cg13631318 |
| LAML | ENSG00000166278 | cg24654874 |
| LAML | ENSG00000125434 | cg19697725 |
| LAML | ENSG00000107140 | cg06216677 |
| LAML | ENSG00000153879 | cg07922062 |
| ∗Please click the gene id for more information. |
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| Female-specific cis-eQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | CpG ID |
| LAML | ENSG00000167701 | cg16587265,cg17869161,cg02185216,cg21040069 |
| LAML | ENSG00000184292 | cg21536783 |
| LAML | ENSG00000157017 | cg07348809 |
| LAML | ENSG00000092067 | cg16229875 |
| LAML | ENSG00000183337 | cg21180513,cg12045126,cg14261068,cg24156613 |
| LAML | ENSG00000188643 | cg11820824 |
| LAML | ENSG00000105227 | cg03251852 |
| LAML | ENSG00000181409 | cg05569220,cg01633363 |
| LAML | ENSG00000214063 | cg08057037,cg04552852,cg12464638 |
| LAML | ENSG00000114654 | cg20230732,cg03406011 |
| LAML | ENSG00000145431 | cg11598720 |
| LAML | ENSG00000116731 | cg23267665 |
| LAML | ENSG00000131873 | cg17794524 |
| LAML | ENSG00000114107 | cg15095727 |
| LAML | ENSG00000154358 | cg19247726 |
| LAML | ENSG00000243147 | cg22759265 |
| LAML | ENSG00000108604 | cg19016967 |
| LAML | ENSG00000124107 | cg14609407 |
| LAML | ENSG00000154133 | cg10148841 |
| LAML | ENSG00000196776 | cg02487233 |
| LAML | ENSG00000099864 | cg14695566 |
| ∗Please click the gene id for more information. |
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| Opposite sex-biased cis-eQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | CpG ID |
| ∗Please click the gene id for more information. |
Top |
sQTM regulation in LAML |
|
| Male-specific cis-sQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | CpG ID |
| ∗Please click the gene id for more information. |
|
| Female-specific cis-sQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | CpG ID |
| ∗Please click the gene id for more information. |
|
| Opposite sex-biased cis-sQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | CpG ID |
| ∗Please click the gene id for more information. |
