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Center for Computational Systems Medicine
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Summary of cancer

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Sex-biased mutation in cancer

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Top 20 sex-biased TF-Gene regulation in cancer

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Top 20 sex-biased RBP-ES regulation in cancer

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Sex-biased cis-eQTL regulation in cancer

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Sex-biased cis-sQTL regulation in cancer

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Sex-biased cis-eQTM regulation in cancer

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Sex-biased cis-sQTM regulation in cancer

Cancer Type: KICH

Summary for KICH

check buttonPatient number summary of KICH.
Cancer TypeMale Tumor PatientsFemale Tumor PatientsMale Normal PatientsFemale Normal Patients
KICH39261212

check buttonResult summary of KICH.
MolecularSex-biased molecularsFemale-specific DEmolecularsMale-specific DEmoleculars
ASevents

11

175

168

A-to-I editing

44

3

3

Coding Gene

24

908

432

lncRNA16039
Methy

322

-

-

miRNA52915
Protein

26

-

-

∗Please click the number for more information.
∗For lncRNA and miRNA, Please click the download page for more detail.

check buttonFunctional enrichment analysis of KICH.
Functional enrichment analysis
Cancer TypeTermGenesType
KICHCell adhesion moleculesVCAN;CD99Malebaised
KICHMucin type O-glycan biosynthesisGALNT14Malebaised
KICHOther types of O-glycan biosynthesisGALNT14Malebaised
KICHGlutathione metabolismGSTM3Femalebaised
KICHEpithelial cell signaling in Helicobacter pylori infectionJAM3Femalebaised
KICHMetabolism of xenobiotics by cytochrome P450GSTM3Femalebaised
KICHDrug metabolismGSTM3Femalebaised
KICHLeukocyte transendothelial migrationJAM3Femalebaised
KICHFluid shear stress and atherosclerosisGSTM3Femalebaised
KICHCell adhesion moleculesJAM3Femalebaised
KICHHepatocellular carcinomaGSTM3Femalebaised
KICHTight junctionJAM3Femalebaised

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Sex-biased mutation in KICH

check buttonSex-biased mutation in KICH.

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TF-Gene regulation in KICH

check buttonTop20 sex-biased TF-Gene regulation in KICH.
UCSC result

check buttonTable of top20 male-biased TF-Gene regulation in KICH.
Cancer TypeSexGene IDTFGene SymbolScore
KICHMale

ENSG00000270672

ZNF211MTRNR2L69.2651390712885
KICHMale

ENSG00000255823

LHX9MTRNR2L88.74767282006717
KICHMale

ENSG00000270188

ONECUT3MTRNR2L118.74482384695375
KICHMale

ENSG00000256045

DMRT2MTRNR2L108.64817674650297
KICHMale

ENSG00000255823

NR4A2MTRNR2L88.63244296167745
KICHMale

ENSG00000256045

ALX1MTRNR2L108.59124673563102
KICHMale

ENSG00000255823

ZNF232MTRNR2L88.5250991992772
KICHMale

ENSG00000270188

HOXA13MTRNR2L118.50926010414216
KICHMale

ENSG00000256045

POU4F3MTRNR2L108.48762666393866
KICHMale

ENSG00000256045

HOXA13MTRNR2L108.46664308277682
KICHMale

ENSG00000255823

SOX14MTRNR2L88.35971815715104
KICHMale

ENSG00000256045

POU4F1MTRNR2L108.29332703662046
KICHMale

ENSG00000270188

HOXC10MTRNR2L118.27894566285385
KICHMale

ENSG00000125255

HNF1BSLC10A28.20049050093768
KICHMale

ENSG00000256045

HOXC10MTRNR2L108.18620761681888
KICHMale

ENSG00000255823

SOX15MTRNR2L88.17759076391956
KICHMale

ENSG00000255823

SOX18MTRNR2L88.14606017277669
KICHMale

ENSG00000231861

BARX2OR5K28.1335371954997
KICHMale

ENSG00000270188

NFAT5MTRNR2L118.11789092012784
KICHMale

ENSG00000270672

DMRTA2MTRNR2L67.99939309814173
∗Please click the gene id for more information.

check buttonTable of top20 female-biased TF-Gene regulation in KICH.
Cancer TypeSexGene IDTFGene SymbolScore
KICHFemale

ENSG00000170681

HNF1BCAVIN49.44540571209614
KICHFemale

ENSG00000170681

ZNF418CAVIN49.31936616869347
KICHFemale

ENSG00000170681

FOXO1CAVIN49.10853193688424
KICHFemale

ENSG00000170681

FOXD3CAVIN49.006310069577
KICHFemale

ENSG00000170681

FOXF1CAVIN48.98971354341675
KICHFemale

ENSG00000170681

FOXC1CAVIN48.93203157428992
KICHFemale

ENSG00000270188

ZNF331MTRNR2L118.88172469405327
KICHFemale

ENSG00000270188

PLAG1MTRNR2L118.87014742928613
KICHFemale

ENSG00000270188

ZBTB12MTRNR2L118.8677410229559
KICHFemale

ENSG00000270188

ZNF429MTRNR2L118.54126326298065
KICHFemale

ENSG00000170681

ZNF879CAVIN48.53033032072669
KICHFemale

ENSG00000183395

DMRT2PMCH8.47470393002147
KICHFemale

ENSG00000255823

ZNF429MTRNR2L88.44220306688912
KICHFemale

ENSG00000170681

ZNF3CAVIN48.43584722220498
KICHFemale

ENSG00000262406

ZNF418MMP128.38159968101946
KICHFemale

ENSG00000183395

FOXD2PMCH8.20503885901851
KICHFemale

ENSG00000183395

FOXB1PMCH8.18988198802742
KICHFemale

ENSG00000170681

FOXC2CAVIN48.16974935448231
KICHFemale

ENSG00000164185

CUX2ZNF4748.15380115340725
KICHFemale

ENSG00000255823

ZNF768MTRNR2L88.07782814975442
∗Please click the gene id for more information.

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RBP-ES regulation in KICH

check buttonTop20 sex-biased RBP-ES regulation in KICH.
UCSC result

check buttonTable of top20 male-biased RBP-ES regulation in KICH.
Cancer TypeSexGene IDRBPESScore
KICHMale

ENSG00000122566

MSI1exon_skip_47432817.3783512044803
KICHMale

ENSG00000130638

RBM3exon_skip_36650117.0603342042721
KICHMale

ENSG00000156931

RBM3exon_skip_37997817.0603342042721
KICHMale

ENSG00000158985

RBM3exon_skip_43716017.0603342042721
KICHMale

ENSG00000103855

STAR-PAPexon_skip_12338816.3882246831108
KICHMale

ENSG00000069966

STAR-PAPexon_skip_12716616.3882246831108
KICHMale

ENSG00000117593

STAR-PAPexon_skip_1423516.3882246831108
KICHMale

ENSG00000089006

STAR-PAPexon_skip_35527916.3882246831108
KICHMale

ENSG00000131375

STAR-PAPexon_skip_37200816.3882246831108
KICHMale

ENSG00000136631

STAR-PAPexon_skip_964716.3882246831108
KICHMale

ENSG00000204713

STAR-PAPexon_skip_45687815.8099243166708
KICHMale

ENSG00000122786

MSI1exon_skip_47147115.4178231656862
KICHMale

ENSG00000175221

ANKHD1exon_skip_31239215.3731527710259
KICHMale

ENSG00000122545

DAZAP1exon_skip_46538515.372746632525
KICHMale

ENSG00000177189

DAZAP1exon_skip_51429915.372746632525
KICHMale

ENSG00000110497

DAZAP1exon_skip_7057915.372746632525
KICHMale

ENSG00000196510

DAZAP1exon_skip_9621715.372746632525
KICHMale

ENSG00000185624

ANKHD1exon_skip_29458015.3498233798717
KICHMale

ENSG00000113163

ANKHD1exon_skip_44269815.3390526484514
KICHMale

ENSG00000115464

QKIexon_skip_33943515.3061209751109
∗Please click the gene id for more information.

check buttonTable of top20 female-biased RBP-ES regulation in KICH.
Cancer TypeSexGene IDRBPESScore
KICHFemale

ENSG00000101966

MSI1exon_skip_51227717.376633442672
KICHFemale

ENSG00000129925

ANKHD1exon_skip_14021417.3459444386878
KICHFemale

ENSG00000154265

ANKHD1exon_skip_29291917.3459444386878
KICHFemale

ENSG00000104368

ANKHD1exon_skip_48946817.3459444386878
KICHFemale

ENSG00000164961

RBM3exon_skip_49234317.0603707080423
KICHFemale

ENSG00000167978

STAR-PAPexon_skip_13261316.3861723112868
KICHFemale

ENSG00000124228

STAR-PAPexon_skip_35292016.3861723112868
KICHFemale

ENSG00000120705

STAR-PAPexon_skip_44457416.3861723112868
KICHFemale

ENSG00000135469

STAR-PAPexon_skip_8422916.3861723112867
KICHFemale

ENSG00000104205

MSI1exon_skip_48384215.5773536268447
KICHFemale

ENSG00000171503

MSI1exon_skip_42694615.413238363494
KICHFemale

ENSG00000131966

DAZAP1exon_skip_10683115.3649542015238
KICHFemale

ENSG00000145703

DAZAP1exon_skip_43581115.3649542015238
KICHFemale

ENSG00000169189

ANKHD1exon_skip_14330815.3649077261364
KICHFemale

ENSG00000185627

MSI1exon_skip_5517915.327555120239
KICHFemale

ENSG00000072506

ANKHD1exon_skip_51508115.3248026518311
KICHFemale

ENSG00000170832

MSI1exon_skip_29215115.3183333359188
KICHFemale

ENSG00000140859

ANKHD1exon_skip_14476015.3051064538645
KICHFemale

ENSG00000174442

QKIexon_skip_12294115.3045257521468
KICHFemale

ENSG00000162441

QKIexon_skip_2170715.3045257521468
∗Please click the gene id for more information.

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eQTL regulation in KICH

lncrna_protein
check buttonTop Male-specific cis-sQTM regulation (FDR <1e-5).
Cancer TypeGene IDGene NameSNP ID
∗Please click the gene id for more information.

lncrna_protein
check buttonFemale-specific cis-eQTL regulation (FDR <1e-5).
Cancer TypeGene IDGene NameSNP ID
∗Please click the gene id for more information.

lncrna_protein
check buttonOpposite sex-biased cis-eQTL regulation (FDR <1e-5).
Cancer TypeGene IDGene NameSNP ID
∗Please click the gene id for more information.

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sQTL regulation in KICH

lncrna_protein
check buttonMale-specific cis-sQTL regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDSNP ID
∗Please click the gene id for more information.

lncrna_protein
check buttonFemale-specific cis-sQTL regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDSNP ID
∗Please click the gene id for more information.

lncrna_protein
check buttonOpposite sex-biased cis-sQTL regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDSNP ID
∗Please click the gene id for more information.

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eQTM regulation in KICH

lncrna_protein
check buttonMale-specific cis-eQTM regulation (FDR <1e-5).
Cancer TypeGene IDCpG ID
∗Please click the gene id for more information.

lncrna_protein
check buttonFemale-specific cis-eQTM regulation (FDR <1e-5).
Cancer TypeGene IDCpG ID
∗Please click the gene id for more information.

lncrna_protein
check buttonOpposite sex-biased cis-eQTM regulation (FDR <1e-5).
Cancer TypeGene IDCpG ID
∗Please click the gene id for more information.

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sQTM regulation in KICH

lncrna_protein
check buttonMale-specific cis-sQTM regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDCpG ID
∗Please click the gene id for more information.

lncrna_protein
check buttonFemale-specific cis-sQTM regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDCpG ID
∗Please click the gene id for more information.

lncrna_protein
check buttonOpposite sex-biased cis-sQTM regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDCpG ID
∗Please click the gene id for more information.