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Cancer Type: GBM |
Summary for GBM |
 Patient number summary of GBM. |
| Cancer Type | Male Tumor Patients | Female Tumor Patients | Male Normal Patients | Female Normal Patients |
| GBM | 109 | 59 | 0 | 0 |
| Result summary of GBM. |
| Molecular | Sex-biased moleculars | Female-specific DEmoleculars | Male-specific DEmoleculars |
| ASevents | 2 | - | - |
| A-to-I editing | 94 | - | - |
| Coding Gene | 22 | - | - |
| lncRNA | 6 | - | - |
| Methy | 3176 | - | - |
| miRNA | - | - | - |
| Protein | 28 | - | - |
| ∗Please click the number for more information. ∗For lncRNA and miRNA, Please click the download page for more detail. |
| Functional enrichment analysis of GBM. |
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| Cancer Type | Term | Genes | Type | ||||
| GBM | Fat digestion and absorption | CD36 | Malebaised | ||||
Top |
Sex-biased mutation in GBM |
| Sex-biased mutation in GBM. |
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Top |
TF-Gene regulation in GBM |
| Top20 sex-biased TF-Gene regulation in GBM. |
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| Table of top20 male-biased TF-Gene regulation in GBM. |
| Cancer Type | Sex | Gene ID | TF | Gene Symbol | Score |
| GBM | Male | ENSG00000187372 | ZNF2 | PCDHB13 | 8.14409577036455 |
| GBM | Male | ENSG00000187372 | REL | PCDHB13 | 7.81171623565044 |
| GBM | Male | ENSG00000112818 | ZNF418 | MEP1A | 7.25331074557379 |
| GBM | Male | ENSG00000262406 | ZNF418 | MMP12 | 7.16431125673217 |
| GBM | Male | ENSG00000204033 | ZIC5 | LRIT2 | 7.14352550189625 |
| GBM | Male | ENSG00000204033 | ZIC4 | LRIT2 | 7.10784855129672 |
| GBM | Male | ENSG00000276547 | ZNF793 | PCDHGB5 | 6.97315465175269 |
| GBM | Male | ENSG00000204033 | ZNF101 | LRIT2 | 6.91787374848513 |
| GBM | Male | ENSG00000204033 | ASCL2 | LRIT2 | 6.89735400666044 |
| GBM | Male | ENSG00000204033 | ZIC1 | LRIT2 | 6.89126963239907 |
| GBM | Male | ENSG00000120327 | ZNF2 | PCDHB14 | 6.8748407432022 |
| GBM | Male | ENSG00000143631 | POU4F2 | FLG | 6.86353387378684 |
| GBM | Male | ENSG00000204033 | ATOH1 | LRIT2 | 6.81748146577141 |
| GBM | Male | ENSG00000276547 | ZNF674 | PCDHGB5 | 6.7743469979056 |
| GBM | Male | ENSG00000143631 | HOXC10 | FLG | 6.74773773516031 |
| GBM | Male | ENSG00000253953 | FOXA3 | PCDHGB4 | 6.74042984682202 |
| GBM | Male | ENSG00000254122 | ZNF430 | PCDHGB7 | 6.73082828574606 |
| GBM | Male | ENSG00000204033 | TCF12 | LRIT2 | 6.6851867894603 |
| GBM | Male | ENSG00000120328 | ZNF2 | PCDHB12 | 6.6510580180728 |
| GBM | Male | ENSG00000120324 | ZNF2 | PCDHB10 | 6.64453860465268 |
| ∗Please click the gene id for more information. |
| Table of top20 female-biased TF-Gene regulation in GBM. |
| Cancer Type | Sex | Gene ID | TF | Gene Symbol | Score |
| GBM | Female | ENSG00000111536 | ZNF487 | IL26 | 8.65090909207516 |
| GBM | Female | ENSG00000180332 | ZNF418 | KCTD4 | 7.66532122337816 |
| GBM | Female | ENSG00000276547 | NKX3-1 | PCDHGB5 | 7.39516985106089 |
| GBM | Female | ENSG00000262406 | NEUROD2 | MMP12 | 7.3102356830404 |
| GBM | Female | ENSG00000181092 | HMX1 | ADIPOQ | 7.19323734110782 |
| GBM | Female | ENSG00000182447 | ZNF418 | OTOL1 | 7.19092279931599 |
| GBM | Female | ENSG00000253953 | ZNF793 | PCDHGB4 | 7.15334470218518 |
| GBM | Female | ENSG00000156239 | MAFF | N6AMT1 | 7.12202230983263 |
| GBM | Female | ENSG00000164821 | ZNF35 | DEFA4 | 7.11443096774831 |
| GBM | Female | ENSG00000181092 | ZNF354A | ADIPOQ | 6.9647869924855 |
| GBM | Female | ENSG00000253953 | ZNF674 | PCDHGB4 | 6.92797338564053 |
| GBM | Female | ENSG00000276547 | ZNF334 | PCDHGB5 | 6.92008000474856 |
| GBM | Female | ENSG00000156239 | MAFA | N6AMT1 | 6.89459531946439 |
| GBM | Female | ENSG00000276547 | FOXL1 | PCDHGB5 | 6.73807551800453 |
| GBM | Female | ENSG00000253846 | ZNF605 | PCDHGA10 | 6.72738855214404 |
| GBM | Female | ENSG00000276547 | ZNF418 | PCDHGB5 | 6.68031932999745 |
| GBM | Female | ENSG00000156239 | MAF | N6AMT1 | 6.6712971402913 |
| GBM | Female | ENSG00000233670 | HIC2 | PIRT | 6.65925731107259 |
| GBM | Female | ENSG00000212124 | ZNF418 | TAS2R19 | 6.55179951028489 |
| GBM | Female | ENSG00000233670 | ZNF667 | PIRT | 6.52320457142901 |
| ∗Please click the gene id for more information. |
Top |
RBP-ES regulation in GBM |
| Top20 sex-biased RBP-ES regulation in GBM. |
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| Table of top20 male-biased RBP-ES regulation in GBM. |
| Cancer Type | Sex | Gene ID | RBP | ES | Score |
| GBM | Male | ENSG00000134057 | MSI1 | exon_skip_435219 | 17.2020910396739 |
| GBM | Male | ENSG00000167978 | STAR-PAP | exon_skip_132613 | 16.2421873796601 |
| GBM | Male | ENSG00000185246 | QKI | exon_skip_106324 | 15.4333677078945 |
| GBM | Male | ENSG00000157637 | ZNF638 | exon_skip_294349 | 15.1814559086196 |
| GBM | Male | ENSG00000035681 | DAZAP1 | exon_skip_489912 | 14.6153631605077 |
| GBM | Male | ENSG00000092203 | RBMS1 | exon_skip_105123 | 14.3362635255665 |
| GBM | Male | ENSG00000116679 | RBMS1 | exon_skip_35080 | 14.3362635255665 |
| GBM | Male | ENSG00000151465 | RBMS1 | exon_skip_39685 | 13.8756130702985 |
| GBM | Male | ENSG00000158195 | QKI | exon_skip_23601 | 13.553189948105 |
| GBM | Male | ENSG00000167522 | RBM8A | exon_skip_147019 | 13.5512116473075 |
| GBM | Male | ENSG00000167110 | RBM3 | exon_skip_507424 | 13.4904422076632 |
| GBM | Male | ENSG00000135486 | MSI1 | exon_skip_83523 | 13.4491391611587 |
| GBM | Male | ENSG00000183258 | HNRNPA1L2 | exon_skip_446647 | 13.3320227340208 |
| GBM | Male | ENSG00000120705 | RBM42 | exon_skip_444578 | 13.2997676279663 |
| GBM | Male | ENSG00000075413 | DAZAP1 | exon_skip_110376 | 13.1743361009872 |
| GBM | Male | ENSG00000118705 | SFPQ | exon_skip_351524 | 13.1143594557497 |
| GBM | Male | ENSG00000071189 | STAR-PAP | exon_skip_473979 | 13.1033831684425 |
| GBM | Male | ENSG00000110092 | ZNF638 | exon_skip_62685 | 13.1024500201936 |
| GBM | Male | ENSG00000164830 | SFPQ | exon_skip_485627 | 13.0114025558031 |
| GBM | Male | ENSG00000149541 | HNRNPA1L2 | exon_skip_73465 | 12.9802548866176 |
| ∗Please click the gene id for more information. |
| Table of top20 female-biased RBP-ES regulation in GBM. |
| Cancer Type | Sex | Gene ID | RBP | ES | Score |
| GBM | Female | ENSG00000158985 | RBM3 | exon_skip_437160 | 16.8739432502855 |
| GBM | Female | ENSG00000100650 | STAR-PAP | exon_skip_107749 | 16.2337230571714 |
| GBM | Female | ENSG00000103855 | STAR-PAP | exon_skip_123388 | 16.2337230571714 |
| GBM | Female | ENSG00000124228 | STAR-PAP | exon_skip_352920 | 16.2337230571714 |
| GBM | Female | ENSG00000135469 | STAR-PAP | exon_skip_84229 | 15.6438855966058 |
| GBM | Female | ENSG00000171109 | QKI | exon_skip_379576 | 15.4345154853064 |
| GBM | Female | ENSG00000120137 | QKI | exon_skip_446112 | 15.4345154853064 |
| GBM | Female | ENSG00000061794 | QKI | exon_skip_80932 | 15.4345154853064 |
| GBM | Female | ENSG00000104064 | MSI1 | exon_skip_127026 | 15.2290882178368 |
| GBM | Female | ENSG00000157181 | ZNF638 | exon_skip_14904 | 15.1897381837168 |
| GBM | Female | ENSG00000169750 | ZNF638 | exon_skip_284588 | 15.1897381837168 |
| GBM | Female | ENSG00000090273 | ZNF638 | exon_skip_3041 | 15.1897381837168 |
| GBM | Female | ENSG00000110911 | ZNF638 | exon_skip_92129 | 15.1897381837168 |
| GBM | Female | ENSG00000115380 | MSI1 | exon_skip_339301 | 15.1536162520986 |
| GBM | Female | ENSG00000182179 | DAZAP1 | exon_skip_384361 | 15.1347022081401 |
| GBM | Female | ENSG00000106070 | DAZAP1 | exon_skip_475565 | 15.1347022081401 |
| GBM | Female | ENSG00000123374 | RBM3 | exon_skip_83851 | 14.9808519996122 |
| GBM | Female | ENSG00000155099 | QKI | exon_skip_490809 | 14.9274020305363 |
| GBM | Female | ENSG00000141959 | ANKHD1 | exon_skip_360611 | 14.7493492779009 |
| GBM | Female | ENSG00000006125 | ANKHD1 | exon_skip_150976 | 14.7025119442038 |
| ∗Please click the gene id for more information. |
Top |
eQTL regulation in GBM |
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| Top Male-specific cis-sQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | SNP ID |
| ∗Please click the gene id for more information. |
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| Female-specific cis-eQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | SNP ID |
| GBM | ENSG00000160963 | COL26A1 | rs10259258,rs9986717,rs9986718,rs9986906,rs28760410,rs28458843,rs28428169,rs28689815,rs10250505,rs10250845,rs10253888,rs10238454,rs10238353,rs10267802,rs10254278,rs10254516,rs10268365,rs10239458,rs10258766,rs10272839,rs75779974,rs28759108,rs28572063,rs28690333,rs10250975,rs10266584,rs10251110,rs10280672,rs10251651,rs10251541,rs12334045,rs9656067,rs10263134,rs10233982,rs13437959,rs13437962 |
| GBM | ENSG00000184254 | ALDH1A3 | rs4646672,rs4646676,rs4646677,rs4246323,rs4246326,rs4646681,rs4646683,rs4246325,rs3803430,rs4646690,rs1802603,rs73480637,rs7170202,rs4646680 |
| ∗Please click the gene id for more information. |
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| Opposite sex-biased cis-eQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | SNP ID |
| ∗Please click the gene id for more information. |
Top |
sQTL regulation in GBM |
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| Male-specific cis-sQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | SNP ID |
| ∗Please click the gene id for more information. |
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| Female-specific cis-sQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | SNP ID |
| ∗Please click the gene id for more information. |
|
| Opposite sex-biased cis-sQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | SNP ID |
| ∗Please click the gene id for more information. |
Top |
eQTM regulation in GBM |
|
| Male-specific cis-eQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | CpG ID |
| ∗Please click the gene id for more information. |
|
| Female-specific cis-eQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | CpG ID |
| ∗Please click the gene id for more information. |
|
| Opposite sex-biased cis-eQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | CpG ID |
| ∗Please click the gene id for more information. |
Top |
sQTM regulation in GBM |
|
| Male-specific cis-sQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | CpG ID |
| ∗Please click the gene id for more information. |
|
| Female-specific cis-sQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | CpG ID |
| ∗Please click the gene id for more information. |
|
| Opposite sex-biased cis-sQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | CpG ID |
| ∗Please click the gene id for more information. |
