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Cancer Type: ESCA |
Summary for ESCA |
 Patient number summary of ESCA. |
| Cancer Type | Male Tumor Patients | Female Tumor Patients | Male Normal Patients | Female Normal Patients |
| ESCA | 139 | 23 | 8 | 3 |
| Result summary of ESCA. |
| Molecular | Sex-biased moleculars | Female-specific DEmoleculars | Male-specific DEmoleculars |
| ASevents | 2 | - | 382 |
| A-to-I editing | 181 | - | 6 |
| Coding Gene | 94 | - | 2116 |
| lncRNA | 2 | - | 138 |
| Methy | 1935 | - | 743 |
| miRNA | - | 18 | 43 |
| Protein | 15 | - | - |
| ∗Please click the number for more information. ∗For lncRNA and miRNA, Please click the download page for more detail. |
| Functional enrichment analysis of ESCA. |
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| Cancer Type | Term | Genes | Type | ||||
| ESCA | Protein digestion and absorption | CPA2;SLC6A19;COL11A1;PGA3;PGA5 | Malebaised | ||||
| ESCA | Fat digestion and absorption | LIPF;APOA1;CEL | Malebaised | ||||
| ESCA | Drug metabolism | GSTM3;GSTA1;UGT2B15;CES1 | Malebaised | ||||
| ESCA | Cholesterol metabolism | APOH;APOA2;APOA1 | Malebaised | ||||
| ESCA | Metabolism of xenobiotics by cytochrome P450 | GSTM3;UGT2B15;GSTA1 | Malebaised | ||||
| ESCA | Gastric acid secretion | ATP4A;SLC9A4;SST | Malebaised | ||||
| ESCA | Complement and coagulation cascades | FGB;VTN;FGG | Malebaised | ||||
| ESCA | Staphylococcus aureus infection | DEFA6;DEFA5;FGG | Malebaised | ||||
| ESCA | Pancreatic secretion | CPA2;CLCA1;CEL | Malebaised | ||||
| ESCA | Fluid shear stress and atherosclerosis | GSTM3;GSTA1;NOX1 | Malebaised | ||||
| ESCA | Glutathione metabolism | GSTM3;GSTA1 | Malebaised | ||||
| ESCA | PI3K-Akt signaling pathway | NGFR;COL9A2;FGF3;EGFR;ITGA9 | Femalebaised | ||||
| ESCA | Focal adhesion | COL9A2;EGFR;ITGA9 | Femalebaised | ||||
| ESCA | Rap1 signaling pathway | NGFR;FGF3;EGFR | Femalebaised | ||||
| ESCA | Regulation of actin cytoskeleton | FGF3;EGFR;ITGA9 | Femalebaised | ||||
| ESCA | Ras signaling pathway | NGFR;FGF3;EGFR | Femalebaised | ||||
| ESCA | Melanoma | FGF3;EGFR | Femalebaised | ||||
| ESCA | MAPK signaling pathway | NGFR;FGF3;EGFR | Femalebaised | ||||
| ESCA | Human papillomavirus infection | COL9A2;EGFR;ITGA9 | Femalebaised | ||||
| ESCA | ECM-receptor interaction | COL9A2;ITGA9 | Femalebaised | ||||
| ESCA | FoxO signaling pathway | S1PR4;EGFR | Femalebaised | ||||
| ESCA | Breast cancer | FGF3;EGFR | Femalebaised | ||||
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Sex-biased mutation in ESCA |
| Sex-biased mutation in ESCA. |
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Top |
TF-Gene regulation in ESCA |
| Top20 sex-biased TF-Gene regulation in ESCA. |
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| Table of top20 male-biased TF-Gene regulation in ESCA. |
| Cancer Type | Sex | Gene ID | TF | Gene Symbol | Score |
| ESCA | Male | ENSG00000133805 | CEBPB | AMPD3 | 9.35226000036314 |
| ESCA | Male | ENSG00000133805 | CEBPE | AMPD3 | 8.96413369410458 |
| ESCA | Male | ENSG00000187372 | TBX15 | PCDHB13 | 8.74781276359596 |
| ESCA | Male | ENSG00000178965 | OVOL1 | ERICH3 | 8.46337148739538 |
| ESCA | Male | ENSG00000187372 | ZNF33B | PCDHB13 | 8.46298829666358 |
| ESCA | Male | ENSG00000187372 | ZNF615 | PCDHB13 | 8.30631734743664 |
| ESCA | Male | ENSG00000230873 | HOXC12 | STMND1 | 8.27733875920711 |
| ESCA | Male | ENSG00000187372 | ZNF490 | PCDHB13 | 8.20365033800956 |
| ESCA | Male | ENSG00000187372 | ZNF76 | PCDHB13 | 7.75581240840808 |
| ESCA | Male | ENSG00000187372 | ZNF143 | PCDHB13 | 7.73870867488585 |
| ESCA | Male | ENSG00000116031 | MESP2 | CD207 | 7.71413922938057 |
| ESCA | Male | ENSG00000187372 | MEF2A | PCDHB13 | 7.6637027327895 |
| ESCA | Male | ENSG00000116031 | MSGN1 | CD207 | 7.53219955554827 |
| ESCA | Male | ENSG00000254122 | MEOX2 | PCDHGB7 | 7.4686013681155 |
| ESCA | Male | ENSG00000187372 | REL | PCDHB13 | 7.45117949523216 |
| ESCA | Male | ENSG00000036054 | OTX1 | TBC1D23 | 7.43273236040402 |
| ESCA | Male | ENSG00000162949 | SOX12 | CAPN13 | 7.41884018828537 |
| ESCA | Male | ENSG00000112972 | ZFHX2 | HMGCS1 | 7.32801568657596 |
| ESCA | Male | ENSG00000178965 | MYBL2 | ERICH3 | 7.20521545704816 |
| ESCA | Male | ENSG00000187527 | OTX2 | ATP13A5 | 7.12861503286846 |
| ∗Please click the gene id for more information. |
| Table of top20 female-biased TF-Gene regulation in ESCA. |
| Cancer Type | Sex | Gene ID | TF | Gene Symbol | Score |
| ESCA | Female | ENSG00000212916 | ONECUT2 | MAP10 | 10.2599704350148 |
| ESCA | Female | ENSG00000212916 | BARX2 | MAP10 | 7.85368789758622 |
| ESCA | Female | ENSG00000212916 | HNF1A | MAP10 | 7.65375169617672 |
| ESCA | Female | ENSG00000244067 | SPDEF | GSTA2 | 7.51883907521453 |
| ESCA | Female | ENSG00000212916 | NR5A2 | MAP10 | 7.4853502680699 |
| ESCA | Female | ENSG00000212916 | ESRRG | MAP10 | 7.28120561039108 |
| ESCA | Female | ENSG00000168806 | NFATC3 | LCMT2 | 7.13603523725182 |
| ESCA | Female | ENSG00000168806 | IRX3 | LCMT2 | 7.00442993117293 |
| ESCA | Female | ENSG00000198680 | TEAD4 | TUSC1 | 6.99466174584084 |
| ESCA | Female | ENSG00000244067 | FOXH1 | GSTA2 | 6.98088241420635 |
| ESCA | Female | ENSG00000212916 | NR6A1 | MAP10 | 6.93709713492316 |
| ESCA | Female | ENSG00000143520 | ZNF235 | FLG2 | 6.85556033907799 |
| ESCA | Female | ENSG00000168806 | IRX1 | LCMT2 | 6.73795069187333 |
| ESCA | Female | ENSG00000212916 | ESRRB | MAP10 | 6.72184621618324 |
| ESCA | Female | ENSG00000177613 | HNF1A | CSTF2T | 6.71237802499074 |
| ESCA | Female | ENSG00000169385 | EHF | RNASE2 | 6.50069411824684 |
| ESCA | Female | ENSG00000234068 | ZSCAN23 | PAGE2 | 6.46930216528947 |
| ESCA | Female | ENSG00000212916 | NR5A1 | MAP10 | 6.46230020125356 |
| ESCA | Female | ENSG00000248713 | ZNF19 | C4orf54 | 6.42359859190025 |
| ESCA | Female | ENSG00000197557 | GATA3 | TTC30A | 6.29324339081912 |
| ∗Please click the gene id for more information. |
Top |
RBP-ES regulation in ESCA |
| Top20 sex-biased RBP-ES regulation in ESCA. |
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| Table of top20 male-biased RBP-ES regulation in ESCA. |
| Cancer Type | Sex | Gene ID | RBP | ES | Score |
| ESCA | Male | ENSG00000124155 | STAR-PAP | exon_skip_352379 | 15.7306597325957 |
| ESCA | Male | ENSG00000205133 | MSI1 | exon_skip_490864 | 14.1538277214078 |
| ESCA | Male | ENSG00000137478 | YBX2 | exon_skip_75462 | 13.9226220089875 |
| ESCA | Male | ENSG00000072864 | MSI1 | exon_skip_133736 | 13.9055795639829 |
| ESCA | Male | ENSG00000167110 | RBM3 | exon_skip_507424 | 13.6240894378131 |
| ESCA | Male | ENSG00000179950 | RBM8A | exon_skip_493911 | 13.5132928045343 |
| ESCA | Male | ENSG00000089737 | STAR-PAP | exon_skip_115415 | 13.5074308632249 |
| ESCA | Male | ENSG00000183530 | RBMS1 | exon_skip_368873 | 13.4719532230869 |
| ESCA | Male | ENSG00000150938 | RBM42 | exon_skip_324868 | 13.30198644297 |
| ESCA | Male | ENSG00000197905 | SFPQ | exon_skip_79163 | 13.1992923476709 |
| ESCA | Male | ENSG00000086758 | SFPQ | exon_skip_515136 | 12.8014342158728 |
| ESCA | Male | ENSG00000001084 | ZNF638 | exon_skip_460243 | 12.6594082462731 |
| ESCA | Male | ENSG00000182552 | ZCRB1 | exon_skip_433266 | 12.0964668317934 |
| ESCA | Male | ENSG00000159063 | ZCRB1 | exon_skip_76195 | 12.0785837102617 |
| ESCA | Male | ENSG00000124207 | QKI | exon_skip_352895 | 11.9677026500322 |
| ESCA | Male | ENSG00000148110 | YBX2 | exon_skip_497429 | 11.9586718640455 |
| ESCA | Male | ENSG00000136732 | FXR1 | exon_skip_329453 | 11.9494891841019 |
| ESCA | Male | ENSG00000140937 | FXR1 | exon_skip_145019 | 11.9494891841018 |
| ESCA | Male | ENSG00000172269 | STAR-PAP | exon_skip_77993 | 11.9319960423421 |
| ESCA | Male | ENSG00000126012 | MSI1 | exon_skip_514990 | 11.8926164408105 |
| ∗Please click the gene id for more information. |
| Table of top20 female-biased RBP-ES regulation in ESCA. |
| Cancer Type | Sex | Gene ID | RBP | ES | Score |
| ESCA | Female | ENSG00000164176 | MSI1 | exon_skip_443084 | 16.9294705078389 |
| ESCA | Female | ENSG00000130175 | ANKHD1 | exon_skip_302531 | 16.67351122741 |
| ESCA | Female | ENSG00000099889 | ANKHD1 | exon_skip_367542 | 16.67351122741 |
| ESCA | Female | ENSG00000132561 | ANKHD1 | exon_skip_485121 | 16.67351122741 |
| ESCA | Female | ENSG00000089006 | STAR-PAP | exon_skip_355279 | 16.2182184739424 |
| ESCA | Female | ENSG00000167978 | STAR-PAP | exon_skip_132613 | 16.2182184739423 |
| ESCA | Female | ENSG00000124228 | STAR-PAP | exon_skip_352920 | 16.2182184739423 |
| ESCA | Female | ENSG00000131375 | STAR-PAP | exon_skip_372008 | 16.2182184739423 |
| ESCA | Female | ENSG00000008869 | MSI1 | exon_skip_338293 | 15.1864730717983 |
| ESCA | Female | ENSG00000164292 | MSI1 | exon_skip_436457 | 15.1864730717983 |
| ESCA | Female | ENSG00000182179 | DAZAP1 | exon_skip_384361 | 15.1424701416936 |
| ESCA | Female | ENSG00000106070 | DAZAP1 | exon_skip_475565 | 15.1424701416936 |
| ESCA | Female | ENSG00000119314 | DAZAP1 | exon_skip_505944 | 15.1424701416936 |
| ESCA | Female | ENSG00000131966 | DAZAP1 | exon_skip_106831 | 15.1424701416935 |
| ESCA | Female | ENSG00000076650 | RBM3 | exon_skip_304832 | 15.1420400990705 |
| ESCA | Female | ENSG00000157500 | QKI | exon_skip_375535 | 15.0768169935354 |
| ESCA | Female | ENSG00000120137 | QKI | exon_skip_446112 | 15.0768169935354 |
| ESCA | Female | ENSG00000120438 | QKI | exon_skip_463216 | 15.0768169935354 |
| ESCA | Female | ENSG00000061794 | QKI | exon_skip_80932 | 15.0768169935353 |
| ESCA | Female | ENSG00000111142 | QKI | exon_skip_85934 | 15.0768169935353 |
| ∗Please click the gene id for more information. |
Top |
eQTL regulation in ESCA |
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| Top Male-specific cis-sQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | SNP ID |
| ∗Please click the gene id for more information. |
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| Female-specific cis-eQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | SNP ID |
| ∗Please click the gene id for more information. |
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| Opposite sex-biased cis-eQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | SNP ID |
| ∗Please click the gene id for more information. |
Top |
sQTL regulation in ESCA |
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| Male-specific cis-sQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | SNP ID |
| ∗Please click the gene id for more information. |
|
| Female-specific cis-sQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | SNP ID |
| ∗Please click the gene id for more information. |
|
| Opposite sex-biased cis-sQTL regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | SNP ID |
| ∗Please click the gene id for more information. |
Top |
eQTM regulation in ESCA |
|
| Male-specific cis-eQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | CpG ID |
| ∗Please click the gene id for more information. |
|
| Female-specific cis-eQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | CpG ID |
| ∗Please click the gene id for more information. |
|
| Opposite sex-biased cis-eQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | CpG ID |
| ∗Please click the gene id for more information. |
Top |
sQTM regulation in ESCA |
|
| Male-specific cis-sQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | CpG ID |
| ∗Please click the gene id for more information. |
|
| Female-specific cis-sQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | CpG ID |
| ∗Please click the gene id for more information. |
|
| Opposite sex-biased cis-sQTM regulation (FDR <1e-5). |
| Cancer Type | Gene ID | Gene Name | ES ID | CpG ID |
| ∗Please click the gene id for more information. |
