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Center for Computational Systems Medicine
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Summary of cancer

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Sex-biased mutation in cancer

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Top 20 sex-biased TF-Gene regulation in cancer

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Top 20 sex-biased RBP-ES regulation in cancer

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Sex-biased cis-eQTL regulation in cancer

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Sex-biased cis-sQTL regulation in cancer

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Sex-biased cis-eQTM regulation in cancer

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Sex-biased cis-sQTM regulation in cancer

Cancer Type: DLBC

Summary for DLBC

check buttonPatient number summary of DLBC.
Cancer TypeMale Tumor PatientsFemale Tumor PatientsMale Normal PatientsFemale Normal Patients
DLBC222600

check buttonResult summary of DLBC.
MolecularSex-biased molecularsFemale-specific DEmolecularsMale-specific DEmoleculars
ASevents

8

-

-

A-to-I editing

37

-

-

Coding Gene

16

-

-

lncRNA2--
Methy

1541

-

-

miRNA---
Protein

33

-

-

∗Please click the number for more information.
∗For lncRNA and miRNA, Please click the download page for more detail.

check buttonFunctional enrichment analysis of DLBC.
Functional enrichment analysis
Cancer TypeTermGenesType
DLBCAlzheimer diseaseTUBB2B;WNT11Femalebaised
DLBCPathways of neurodegenerationTUBB2B;WNT11Femalebaised
DLBCBasal cell carcinomaWNT11Femalebaised
DLBCGap junctionTUBB2BFemalebaised
DLBCMelanogenesisWNT11Femalebaised
DLBCSignaling pathways regulating pluripotency of stem cellsWNT11Femalebaised

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Sex-biased mutation in DLBC

check buttonSex-biased mutation in DLBC.
UCSC result

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TF-Gene regulation in DLBC

check buttonTop20 sex-biased TF-Gene regulation in DLBC.
UCSC result

check buttonTable of top20 male-biased TF-Gene regulation in DLBC.
Cancer TypeSexGene IDTFGene SymbolScore
DLBCMale

ENSG00000153132

CEBPBCLGN10.9553065443602
DLBCMale

ENSG00000153132

CEBPECLGN10.9282665861259
DLBCMale

ENSG00000153132

CEBPGCLGN10.7670585603992
DLBCMale

ENSG00000153132

CEBPDCLGN10.6220658586921
DLBCMale

ENSG00000163818

CEBPBLZTFL19.92549902114802
DLBCMale

ENSG00000163818

CEBPELZTFL19.60563223927984
DLBCMale

ENSG00000163818

CEBPDLZTFL19.44398833714881
DLBCMale

ENSG00000163818

CEBPGLZTFL19.40130143045711
DLBCMale

ENSG00000163803

CEBPDPLB18.59275919439744
DLBCMale

ENSG00000163803

CEBPGPLB18.49073327786792
DLBCMale

ENSG00000124429

LHX8POF1B8.035108916714
DLBCMale

ENSG00000145721

ZFHX3LIX17.59994480000606
DLBCMale

ENSG00000145721

NOTOLIX17.56146793766435
DLBCMale

ENSG00000197629

HMX2MPEG17.51676551804441
DLBCMale

ENSG00000119138

ZNF418KLF97.45415811422483
DLBCMale

ENSG00000145721

VSX2LIX17.40660718164246
DLBCMale

ENSG00000124429

DLX3POF1B7.24675861572221
DLBCMale

ENSG00000181092

ZNF423ADIPOQ7.20105054098268
DLBCMale

ENSG00000198734

LHX8F57.18549815653663
∗Please click the gene id for more information.

check buttonTable of top20 female-biased TF-Gene regulation in DLBC.
Cancer TypeSexGene IDTFGene SymbolScore
DLBCFemale

ENSG00000179674

BATFARL147.79514438496446
DLBCFemale

ENSG00000123094

OVOL2RASSF87.53463699938583
DLBCFemale

ENSG00000276547

ZNF334PCDHGB57.39067622222
DLBCFemale

ENSG00000180573

IRX5H2AC67.3360426329934
DLBCFemale

ENSG00000184678

GRHL1H2BC217.1010366455934
DLBCFemale

ENSG00000276547

FOXL1PCDHGB57.05810012384432
DLBCFemale

ENSG00000169245

HNF1ACXCL107.05366939746507
DLBCFemale

ENSG00000176971

TBPFIBIN7.0500714236968
DLBCFemale

ENSG00000176971

LMX1BFIBIN7.0488903885602
DLBCFemale

ENSG00000197629

NFKB2MPEG16.97245732716438
DLBCFemale

ENSG00000276547

ZNF418PCDHGB56.90204597887832
DLBCFemale

ENSG00000169245

IRF3CXCL106.83215782969777
DLBCFemale

ENSG00000176971

ZFP82FIBIN6.7673275920175
DLBCFemale

ENSG00000169245

ZKSCAN2CXCL106.72038874190097
DLBCFemale

ENSG00000102038

CUX2SMARCA16.66817230215183
DLBCFemale

ENSG00000181092

ZNF354AADIPOQ6.66197330390213
DLBCFemale

ENSG00000169245

IRF1CXCL106.63255636868351
DLBCFemale

ENSG00000162783

OSR1IER56.55869678199105
DLBCFemale

ENSG00000253305

FOXA3PCDHGB66.50004856947829
DLBCFemale

ENSG00000181631

ZNF674P2RY136.4994750954485
∗Please click the gene id for more information.

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RBP-ES regulation in DLBC

check buttonTop20 sex-biased RBP-ES regulation in DLBC.
UCSC result

check buttonTable of top20 male-biased RBP-ES regulation in DLBC.
Cancer TypeSexGene IDRBPESScore
DLBCMale

ENSG00000156931

RBM3exon_skip_37997817.4391815590398
DLBCMale

ENSG00000100650

STAR-PAPexon_skip_10774916.9580884370137
DLBCMale

ENSG00000124155

STAR-PAPexon_skip_35237916.9580884370137
DLBCMale

ENSG00000089006

STAR-PAPexon_skip_35527916.9580884370137
DLBCMale

ENSG00000120705

STAR-PAPexon_skip_44457416.9580884370137
DLBCMale

ENSG00000133313

MSI1exon_skip_29747516.1117973521461
DLBCMale

ENSG00000174442

QKIexon_skip_12294115.9478596687348
DLBCMale

ENSG00000023734

QKIexon_skip_8040515.9478596687348
DLBCMale

ENSG00000163964

MSI1exon_skip_38072415.6699539362365
DLBCMale

ENSG00000123374

RBM3exon_skip_8385115.5524680136944
DLBCMale

ENSG00000099385

RBM3exon_skip_14401015.4568071535203
DLBCMale

ENSG00000196510

DAZAP1exon_skip_9621715.4529214393352
DLBCMale

ENSG00000123146

ANKHD1exon_skip_30295515.4320447419933
DLBCMale

ENSG00000083093

MSI1exon_skip_14317215.4109189746003
DLBCMale

ENSG00000100600

ZNF638exon_skip_11532715.1375339324485
DLBCMale

ENSG00000158864

ZNF638exon_skip_1324215.1375339324485
DLBCMale

ENSG00000100266

ZNF638exon_skip_37017115.1375339324485
DLBCMale

ENSG00000114520

RBMS1exon_skip_38756914.8811839971371
DLBCMale

ENSG00000068885

RBMS1exon_skip_38967714.8811839971371
DLBCMale

ENSG00000166033

RBMS1exon_skip_4567614.8811839971371
∗Please click the gene id for more information.

check buttonTable of top20 female-biased RBP-ES regulation in DLBC.
Cancer TypeSexGene IDRBPESScore
DLBCFemale

ENSG00000129925

ANKHD1exon_skip_14021417.5040722707979
DLBCFemale

ENSG00000130638

RBM3exon_skip_36650117.4362758382881
DLBCFemale

ENSG00000158985

RBM3exon_skip_43716017.4362758382881
DLBCFemale

ENSG00000069966

STAR-PAPexon_skip_12716616.9624300017201
DLBCFemale

ENSG00000104064

MSI1exon_skip_12702616.4952755369524
DLBCFemale

ENSG00000162441

QKIexon_skip_2170715.940283623179
DLBCFemale

ENSG00000100628

RBM3exon_skip_11540115.6367883000283
DLBCFemale

ENSG00000170312

MSI1exon_skip_4170915.6340329275953
DLBCFemale

ENSG00000090060

RBM3exon_skip_10977615.5178446185924
DLBCFemale

ENSG00000159840

DAZAP1exon_skip_47202115.4504010161571
DLBCFemale

ENSG00000107140

DAZAP1exon_skip_49569215.4504010161571
DLBCFemale

ENSG00000177189

DAZAP1exon_skip_51429915.4504010161571
DLBCFemale

ENSG00000148303

RBM3exon_skip_50075215.3410466803392
DLBCFemale

ENSG00000140416

ZNF638exon_skip_12256715.1508243140434
DLBCFemale

ENSG00000000460

ZNF638exon_skip_1396415.1508243140434
DLBCFemale

ENSG00000090273

ZNF638exon_skip_304115.1508243140434
DLBCFemale

ENSG00000100650

STAR-PAPexon_skip_10775115.1028626229021
DLBCFemale

ENSG00000153827

STAR-PAPexon_skip_34733614.9563657126973
DLBCFemale

ENSG00000108591

STAR-PAPexon_skip_14949914.9303252698256
DLBCFemale

ENSG00000078142

RBMS1exon_skip_29662414.885034300393
∗Please click the gene id for more information.

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eQTL regulation in DLBC

lncrna_protein
check buttonTop Male-specific cis-sQTM regulation (FDR <1e-5).
Cancer TypeGene IDGene NameSNP ID
∗Please click the gene id for more information.

lncrna_protein
check buttonFemale-specific cis-eQTL regulation (FDR <1e-5).
Cancer TypeGene IDGene NameSNP ID
∗Please click the gene id for more information.

lncrna_protein
check buttonOpposite sex-biased cis-eQTL regulation (FDR <1e-5).
Cancer TypeGene IDGene NameSNP ID
∗Please click the gene id for more information.

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sQTL regulation in DLBC

lncrna_protein
check buttonMale-specific cis-sQTL regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDSNP ID
∗Please click the gene id for more information.

lncrna_protein
check buttonFemale-specific cis-sQTL regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDSNP ID
∗Please click the gene id for more information.

lncrna_protein
check buttonOpposite sex-biased cis-sQTL regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDSNP ID
∗Please click the gene id for more information.

Top

eQTM regulation in DLBC

lncrna_protein
check buttonMale-specific cis-eQTM regulation (FDR <1e-5).
Cancer TypeGene IDCpG ID
∗Please click the gene id for more information.

lncrna_protein
check buttonFemale-specific cis-eQTM regulation (FDR <1e-5).
Cancer TypeGene IDCpG ID
∗Please click the gene id for more information.

lncrna_protein
check buttonOpposite sex-biased cis-eQTM regulation (FDR <1e-5).
Cancer TypeGene IDCpG ID
∗Please click the gene id for more information.

Top

sQTM regulation in DLBC

lncrna_protein
check buttonMale-specific cis-sQTM regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDCpG ID
∗Please click the gene id for more information.

lncrna_protein
check buttonFemale-specific cis-sQTM regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDCpG ID
∗Please click the gene id for more information.

lncrna_protein
check buttonOpposite sex-biased cis-sQTM regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDCpG ID
∗Please click the gene id for more information.