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Center for Computational Systems Medicine
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Summary of cancer

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Sex-biased mutation in cancer

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Top 20 sex-biased TF-Gene regulation in cancer

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Top 20 sex-biased RBP-ES regulation in cancer

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Sex-biased cis-eQTL regulation in cancer

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Sex-biased cis-sQTL regulation in cancer

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Sex-biased cis-eQTM regulation in cancer

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Sex-biased cis-sQTM regulation in cancer

Cancer Type: ACC

Summary for ACC

check buttonPatient number summary of ACC.
Cancer TypeMale Tumor PatientsFemale Tumor PatientsMale Normal PatientsFemale Normal Patients
ACC314800

check buttonResult summary of ACC.
MolecularSex-biased molecularsFemale-specific DEmolecularsMale-specific DEmoleculars
ASevents

5

1

-

A-to-I editing

49

-

-

Coding Gene

179

5

7

lncRNA10--
Methy

2111

-

-

miRNA6--
Protein

44

-

-

∗Please click the number for more information.
∗For lncRNA and miRNA, Please click the download page for more detail.

check buttonFunctional enrichment analysis of ACC.
Functional enrichment analysis
Cancer TypeTermGenesType
ACCStaphylococcus aureus infectionFCGR3A;FCGR2A;KRT17;C5AR1Malebaised
ACCNeutrophil extracellular trap formationFCGR3A;FCGR2A;C5AR1;CASP1Malebaised
ACCCoronavirus diseaseFCGR2A;C5AR1;CASP1;RPS4Y1Malebaised
ACCOsteoclast differentiationFCGR3A;FCGR2A;TREM2Malebaised
ACCPhagosomeCOLEC12;FCGR3A;FCGR2AMalebaised
ACCLegionellosisCASP1;CXCL1Malebaised
ACCNOD-like receptor signaling pathwayAIM2;CASP1;CXCL1Malebaised
ACCCytosolic DNA-sensing pathwayAIM2;CASP1Malebaised
ACCLeishmaniasisFCGR3A;FCGR2AMalebaised
ACCComplement and coagulation cascadesC5AR1;PLAURMalebaised
ACCFc gamma R-mediated phagocytosisFCGR3A;FCGR2AMalebaised
ACCTerpenoid backbone biosynthesisFDPS;IDI1;MVD;ACAT2Femalebaised
ACCPhenylalanine metabolismAOC3;PAH;HPDFemalebaised
ACCPyruvate metabolismACSS2;ACAT2;PCK2Femalebaised
ACCSteroid biosynthesisCYP51A1;LSSFemalebaised
ACCProximal tubule bicarbonate reclamationCA4;PCK2Femalebaised
ACCGlycolysis / GluconeogenesisACSS2;ALDOB;PCK2Femalebaised
ACCPPAR signaling pathwayFABP4;PLIN2;PCK2Femalebaised
ACCCitrate cycle (TCA cycle)ACLY;PCK2Femalebaised
ACCGlyoxylate and dicarboxylate metabolismACSS2;ACAT2Femalebaised
ACCPropanoate metabolismACSS2;ACAT2Femalebaised
ACCTyrosine metabolismAOC3;HPDFemalebaised

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Sex-biased mutation in ACC

check buttonSex-biased mutation in ACC.
UCSC result

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TF-Gene regulation in ACC

check buttonTop20 sex-biased TF-Gene regulation in ACC.
UCSC result

check buttonTable of top20 male-biased TF-Gene regulation in ACC.
Cancer TypeSexGene IDTFGene SymbolScore
ACCMale

ENSG00000000419

TEFDPM19.96843159356488
ACCMale

ENSG00000000419

CENPBD1DPM19.34752696715487
ACCMale

ENSG00000127249

CENPBD1ATP13A49.09810393919478
ACCMale

ENSG00000000419

DBPDPM17.93761409895968
ACCMale

ENSG00000000419

HOXC12DPM17.90454782690756
ACCMale

ENSG00000000419

HOXD12DPM17.88015440543398
ACCMale

ENSG00000178690

ONECUT2DYNAP7.86405532371738
ACCMale

ENSG00000088298

IRX5EDEM27.80821102403616
ACCMale

ENSG00000088298

ZBTB32EDEM27.80774300532649
ACCMale

ENSG00000029559

POU1F1IBSP7.71656175542038
ACCMale

ENSG00000253626

ZNF45EIF5AL17.68684400758099
ACCMale

ENSG00000183395

DMRT2PMCH7.58766053460366
ACCMale

ENSG00000125977

TLX3EIF2S27.55022827520227
ACCMale

ENSG00000116031

MESP2CD2077.50345379128434
ACCMale

ENSG00000158497

HSFY2HMHB17.45760434818656
ACCMale

ENSG00000184895

FOXF2SRY7.40456522523529
ACCMale

ENSG00000158497

MEIS1HMHB17.32250476530907
ACCMale

ENSG00000154007

IRX5ASB177.19027128480153
ACCMale

ENSG00000183395

FOXD2PMCH7.15732403232683
ACCMale

ENSG00000029559

ZFP1IBSP7.14894640340877
∗Please click the gene id for more information.

check buttonTable of top20 female-biased TF-Gene regulation in ACC.
Cancer TypeSexGene IDTFGene SymbolScore
ACCFemale

ENSG00000175820

BCL6BCCDC1688.31051105507274
ACCFemale

ENSG00000165606

DMRTC2DRGX8.13683044660944
ACCFemale

ENSG00000002745

SOX12WNT168.08994291917552
ACCFemale

ENSG00000248713

ONECUT3C4orf547.95669441676209
ACCFemale

ENSG00000139675

LHX8HNRNPA1L27.86846693910232
ACCFemale

ENSG00000248713

SRFC4orf547.83106630254154
ACCFemale

ENSG00000198680

SOX8TUSC17.76087254623635
ACCFemale

ENSG00000248713

HMX1C4orf547.75197934954331
ACCFemale

ENSG00000175820

NANOGCCDC1687.69700296916636
ACCFemale

ENSG00000117601

DMRTC2SERPINC17.67911549565579
ACCFemale

ENSG00000175820

ZNF418CCDC1687.61204394271179
ACCFemale

ENSG00000175820

MEF2ACCDC1687.60633899588092
ACCFemale

ENSG00000248713

LMX1BC4orf547.45897084672236
ACCFemale

ENSG00000248713

ZNF620C4orf547.41335326616209
ACCFemale

ENSG00000165606

OTX2DRGX7.33987594211763
ACCFemale

ENSG00000198680

ZNF45TUSC17.21004965617394
ACCFemale

ENSG00000091138

HOXD11SLC26A37.11747142340418
ACCFemale

ENSG00000180660

VSX1MAB21L17.11744153576858
ACCFemale

ENSG00000188993

ZNF653LRRC666.9812270051931
ACCFemale

ENSG00000180660

PBX4MAB21L16.95298710493775
∗Please click the gene id for more information.

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RBP-ES regulation in ACC

check buttonTop20 sex-biased RBP-ES regulation in ACC.
UCSC result

check buttonTable of top20 male-biased RBP-ES regulation in ACC.
Cancer TypeSexGene IDRBPESScore
ACCMale

ENSG00000134057

MSI1exon_skip_43521917.4958873546237
ACCMale

ENSG00000164961

RBM3exon_skip_49234316.5196656451571
ACCMale

ENSG00000100650

STAR-PAPexon_skip_10774916.4126627310052
ACCMale

ENSG00000124228

STAR-PAPexon_skip_35292016.4126627310052
ACCMale

ENSG00000120705

STAR-PAPexon_skip_44457416.4126627310052
ACCMale

ENSG00000185624

ANKHD1exon_skip_29458015.7823548280394
ACCMale

ENSG00000072506

ANKHD1exon_skip_51508115.7595758702618
ACCMale

ENSG00000169223

ANKHD1exon_skip_44653315.7479510126923
ACCMale

ENSG00000130520

ANKHD1exon_skip_31642415.7302513540174
ACCMale

ENSG00000144591

DAZAP1exon_skip_33406715.4300169154662
ACCMale

ENSG00000106070

DAZAP1exon_skip_47556515.4300169154662
ACCMale

ENSG00000196510

DAZAP1exon_skip_9621715.4300169154662
ACCMale

ENSG00000185246

QKIexon_skip_10632415.3818440960694
ACCMale

ENSG00000162441

QKIexon_skip_2170715.3818440960694
ACCMale

ENSG00000120137

QKIexon_skip_44611215.3818440960694
ACCMale

ENSG00000120451

QKIexon_skip_7866215.3818440960694
ACCMale

ENSG00000061794

QKIexon_skip_8093215.3818440960694
ACCMale

ENSG00000111142

QKIexon_skip_8593415.3818440960694
ACCMale

ENSG00000120438

QKIexon_skip_46321615.3818440960693
ACCMale

ENSG00000090273

ZNF638exon_skip_304115.1111432159489
∗Please click the gene id for more information.

check buttonTable of top20 female-biased RBP-ES regulation in ACC.
Cancer TypeSexGene IDRBPESScore
ACCFemale

ENSG00000175221

ANKHD1exon_skip_31239215.79772219373
ACCFemale

ENSG00000143153

MSI1exon_skip_1393215.564281156588
ACCFemale

ENSG00000122545

DAZAP1exon_skip_46538515.4273186281812
ACCFemale

ENSG00000152942

QKIexon_skip_43531115.3800220213946
ACCFemale

ENSG00000038358

ZNF638exon_skip_13786915.113383093722
ACCFemale

ENSG00000175029

ZNF638exon_skip_5464215.113383093722
ACCFemale

ENSG00000115241

RBM3exon_skip_33789314.554701786357
ACCFemale

ENSG00000100650

STAR-PAPexon_skip_10775114.5488730481047
ACCFemale

ENSG00000166033

RBMS1exon_skip_4567614.3800473943802
ACCFemale

ENSG00000167522

RBM8Aexon_skip_14701914.2363888338553
ACCFemale

ENSG00000138078

MSI1exon_skip_33876714.156855666026
ACCFemale

ENSG00000106400

MSI1exon_skip_47000013.9373570127863
ACCFemale

ENSG00000057608

MSI1exon_skip_4751613.7112523355801
ACCFemale

ENSG00000155975

RBM42exon_skip_48140813.5533786820377
ACCFemale

ENSG00000052126

RBM42exon_skip_8056013.5533786820377
ACCFemale

ENSG00000057608

ANKHD1exon_skip_4751613.5465364803596
ACCFemale

ENSG00000142507

DAZAP1exon_skip_14806313.5200550957876
ACCFemale

ENSG00000079950

QKIexon_skip_46237013.5086033323497
ACCFemale

ENSG00000126067

STAR-PAPexon_skip_2492013.4834930609607
ACCFemale

ENSG00000134759

SFPQexon_skip_29650013.4726839969655
∗Please click the gene id for more information.

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eQTL regulation in ACC

lncrna_protein
check buttonTop Male-specific cis-sQTM regulation (FDR <1e-5).
Cancer TypeGene IDGene NameSNP ID
∗Please click the gene id for more information.

lncrna_protein
check buttonFemale-specific cis-eQTL regulation (FDR <1e-5).
Cancer TypeGene IDGene NameSNP ID
∗Please click the gene id for more information.

lncrna_protein
check buttonOpposite sex-biased cis-eQTL regulation (FDR <1e-5).
Cancer TypeGene IDGene NameSNP ID
∗Please click the gene id for more information.

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sQTL regulation in ACC

lncrna_protein
check buttonMale-specific cis-sQTL regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDSNP ID
∗Please click the gene id for more information.

lncrna_protein
check buttonFemale-specific cis-sQTL regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDSNP ID
∗Please click the gene id for more information.

lncrna_protein
check buttonOpposite sex-biased cis-sQTL regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDSNP ID
∗Please click the gene id for more information.

Top

eQTM regulation in ACC

lncrna_protein
check buttonMale-specific cis-eQTM regulation (FDR <1e-5).
Cancer TypeGene IDCpG ID
∗Please click the gene id for more information.

lncrna_protein
check buttonFemale-specific cis-eQTM regulation (FDR <1e-5).
Cancer TypeGene IDCpG ID
∗Please click the gene id for more information.

lncrna_protein
check buttonOpposite sex-biased cis-eQTM regulation (FDR <1e-5).
Cancer TypeGene IDCpG ID
∗Please click the gene id for more information.

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sQTM regulation in ACC

lncrna_protein
check buttonMale-specific cis-sQTM regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDCpG ID
∗Please click the gene id for more information.

lncrna_protein
check buttonFemale-specific cis-sQTM regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDCpG ID
∗Please click the gene id for more information.

lncrna_protein
check buttonOpposite sex-biased cis-sQTM regulation (FDR <1e-5).
Cancer TypeGene IDGene NameES IDCpG ID
∗Please click the gene id for more information.