|
||||||
|
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Gene: ENSG00000255582 |
Summary for OR10G2 |
Gene summary |
| Gene information | Ensembl ID | ENSG00000255582 | Gene symbol | OR10G2 |
| Gene name | olfactory receptor family 10 subfamily G member 2 | |
| HGNC | 8170 | |
| Entrez ID | 26534 | |
| Gene type | protein_coding | |
| Synonyms | OR10G2| | |
| UniProtAcc | Q8NGC3 |
Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for OR10G2 |
AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure.∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
Landscape of gene expressions across multiple cancer types. |
Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for OR10G2 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for OR10G2 |
Landscape of DNA methylation across multiple cancer types. |
Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg22142137 | chr14:21634875 | CGI:chr14:21510803-21511557 | UTR,promoter,exon,gene body | 6.79e-01 | 8.19e-01 | -3.23e+00 | 1.22e-03 | 1.06e-02 | -1.40e-01 |
| DLBC | cg20077718 | chr14:21635570 | CGI:chr14:21510803-21511557 | promoter | 5.10e-01 | 7.09e-01 | -3.43e+00 | 5.93e-04 | 2.26e-03 | -1.99e-01 |
| CHOL | cg22142137 | chr14:21634875 | CGI:chr14:21510803-21511557 | UTR,promoter,exon,gene body | 6.03e-01 | 7.14e-01 | -2.10e+00 | 3.56e-02 | 4.34e-02 | -1.11e-01 |
| CHOL | cg23493119 | chr14:21634926 | CGI:chr14:21510803-21511557 | UTR,promoter,exon,gene body | 5.24e-01 | 6.69e-01 | -2.45e+00 | 1.42e-02 | 2.68e-02 | -1.45e-01 |
Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUSC | cg22142137 | chr14:21634875 | CGI:chr14:21510803-21511557 | UTR,promoter,exon,gene body | 4.20e-01 | 5.90e-01 | -3.56e+00 | 3.70e-04 | 1.38e-03 | -1.70e-01 |
| LUSC | cg23493119 | chr14:21634926 | CGI:chr14:21510803-21511557 | UTR,promoter,exon,gene body | 5.18e-01 | 7.21e-01 | -3.71e+00 | 2.10e-04 | 9.96e-04 | -2.03e-01 |
| LUSC | cg20077718 | chr14:21635570 | CGI:chr14:21510803-21511557 | promoter | 6.79e-01 | 8.96e-01 | -3.41e+00 | 6.49e-04 | 1.96e-03 | -2.17e-01 |
| BLCA | cg20077718 | chr14:21635570 | CGI:chr14:21510803-21511557 | promoter | 7.10e-01 | 9.06e-01 | -3.31e+00 | 9.46e-04 | 2.17e-03 | -1.96e-01 |
| LIHC | cg22142137 | chr14:21634875 | CGI:chr14:21510803-21511557 | UTR,promoter,exon,gene body | 3.63e-01 | 4.88e-01 | -3.92e+00 | 8.67e-05 | 1.82e-04 | -1.25e-01 |
| LIHC | cg23493119 | chr14:21634926 | CGI:chr14:21510803-21511557 | UTR,promoter,exon,gene body | 4.03e-01 | 5.63e-01 | -4.57e+00 | 4.84e-06 | 1.45e-05 | -1.60e-01 |
| LIHC | cg20077718 | chr14:21635570 | CGI:chr14:21510803-21511557 | promoter | 5.08e-01 | 7.39e-01 | -2.91e+00 | 3.58e-03 | 4.91e-03 | -2.31e-01 |
| CHOL | cg22142137 | chr14:21634875 | CGI:chr14:21510803-21511557 | UTR,promoter,exon,gene body | 7.14e-01 | 5.06e-01 | 2.43e+00 | 1.50e-02 | 2.65e-02 | 2.09e-01 |
| CHOL | cg23493119 | chr14:21634926 | CGI:chr14:21510803-21511557 | UTR,promoter,exon,gene body | 6.69e-01 | 5.14e-01 | 2.65e+00 | 7.96e-03 | 1.92e-02 | 1.55e-01 |
Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRP | cg23493119 | chr14:21634926 | CGI:chr14:21510803-21511557 | UTR,promoter,exon,gene body | 6.78e-01 | 8.25e-01 | -1.98e+00 | 4.78e-02 | 4.84e-02 | -1.47e-01 |
Top |
Exon skipping events with PSI in TCGA for OR10G2 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for OR10G2 |
| ∗Please access CAeditome for RNA editing annotation. |
Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for OR10G2 |
TFs related to OR10G2.∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
OR10G2 related gene.∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for OR10G2 |
RBPs related to ES in OR10G2.∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
OR10G2 related ES.∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of OR10G2 |
Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |