|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
|
Gene: ENSG00000242110 |
Summary for AMACR |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000242110 | Gene symbol | AMACR |
| Gene name | alpha-methylacyl-CoA racemase | |
| HGNC | 451 | |
| Entrez ID | 23600 | |
| Gene type | protein_coding | |
| Synonyms | AMACR|RACE|P504S | |
| UniProtAcc | Q9UHK6 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for AMACR |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| AMACR | 5.24e+02 | 1.28e+00 | 4.68e-01 | 2.74e+00 | 6.08e-03 | 1.56e-02 | BLCA |
| AMACR | 4.51e+02 | -1.36e+00 | 3.78e-01 | -3.61e+00 | 3.04e-04 | 2.44e-03 | ESCA |
| AMACR | 9.05e+02 | -1.78e+00 | 5.64e-01 | -3.16e+00 | 1.58e-03 | 5.05e-03 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for AMACR |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for AMACR |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BLCA | cg23960088 | chr5:34006789 | CGI:chr5:34007691-34008228 | promoter,gene body | 6.83e-01 | 9.45e-01 | -2.01e+00 | 4.41e-02 | 4.53e-02 | -2.62e-01 |
| LIHC | cg23960088 | chr5:34006789 | CGI:chr5:34007691-34008228 | promoter,gene body | 4.32e-01 | 5.96e-01 | -3.52e+00 | 4.25e-04 | 7.42e-04 | -1.64e-01 |
| ESCA | cg23960088 | chr5:34006789 | CGI:chr5:34007691-34008228 | promoter,gene body | 8.24e-01 | 5.74e-01 | 2.80e+00 | 5.12e-03 | 3.43e-02 | 2.50e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
Top |
Exon skipping events with PSI in TCGA for AMACR |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| ESCA | exon_skip_441413 | 8.37e-01 | 9.43e-01 | -2.39e+00 | 1.69e-02 | 3.04e-02 | -1.06e-01 |
| CHOL | exon_skip_441413 | 8.15e-01 | 9.42e-01 | -3.04e+00 | 2.40e-03 | 1.32e-02 | -1.26e-01 |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for AMACR |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for AMACR |
| TFs related to AMACR. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| UVM | ZNF418 | AMACR | 4.33e+00 | 7.56e-03 | 5.80e+00 | 9.91e-01 | Female-biased |
| AMACR related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for AMACR |
| RBPs related to ES in AMACR. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| AMACR related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs10052172 | chr5:42242630:T:C | - | -0.120571290865881 | 0.00237814115904744 | LUSC | Female-baised eQTL |
| rs71616985 | chr5:28471805:C:A | - | 0.182249365135988 | 0.0315295902743033 | STAD | Female-baised eQTL |
| rs17550602 | chr5:33399455:G:C | - | 0.0784932678762161 | 0.0488770478702888 | STAD | Female-baised eQTL |
| rs13157411 | chr5:28751502:C:T | - | 0.0528293599988833 | 0.0389922187712771 | KIRC | Female-baised eQTL |
| rs80215238 | chr5:43157400:G:C | - | 0.187014999238521 | 0.00114521322329652 | BLCA | Female-baised eQTL |
| rs112138035 | chr5:43158260:A:G | - | 0.187014999238521 | 0.00114521322329652 | BLCA | Female-baised eQTL |
| rs77826997 | chr5:43164835:T:C | - | 0.187014999238521 | 0.00114521322329652 | BLCA | Female-baised eQTL |
| rs76651918 | chr5:43193194:A:G | - | 0.188795708362448 | 0.00423033672608294 | BLCA | Female-baised eQTL |
| rs11742417 | chr5:43146167:C:G | - | 0.172838316393471 | 0.0110887035190395 | BLCA | Female-baised eQTL |
| rs139224645 | chr5:43147418:T:C | - | 0.172838316393471 | 0.0110887035190395 | BLCA | Female-baised eQTL |
| rs111663070 | chr5:43150655:G:A | - | 0.172838316393471 | 0.0110887035190395 | BLCA | Female-baised eQTL |
| rs79861885 | chr5:43151845:C:T | - | 0.172838316393471 | 0.0110887035190395 | BLCA | Female-baised eQTL |
| rs74415540 | chr5:43156208:A:G | - | 0.172838316393471 | 0.0110887035190395 | BLCA | Female-baised eQTL |
| rs11744749 | chr5:43163958:G:A | - | 0.172838316393471 | 0.0110887035190395 | BLCA | Female-baised eQTL |
| rs113337588 | chr5:43165153:G:A | - | 0.172838316393471 | 0.0110887035190395 | BLCA | Female-baised eQTL |
| rs10072230 | chr5:43166947:C:T | - | 0.172838316393471 | 0.0110887035190395 | BLCA | Female-baised eQTL |
| rs12173042 | chr5:36599563:G:A | - | 0.16782406164177 | 0.0298248741695994 | BLCA | Female-baised eQTL |
| rs56301812 | chr5:29330932:C:T | - | 0.0536253532948645 | 0.0249314714486799 | LUAD | Female-baised eQTL |
| rs72745443 | chr5:29320856:C:G | - | 0.053615506910644 | 0.0249824276603355 | LUAD | Female-baised eQTL |
| rs4266379 | chr5:34319662:T:C | - | -0.037249000244504 | 0.0278602808445876 | LUAD | Female-baised eQTL |
| rs7730052 | chr5:34320961:T:A | - | -0.037249000244504 | 0.0278602808445876 | LUAD | Female-baised eQTL |
| rs7730236 | chr5:34321059:T:C | - | -0.037249000244504 | 0.0278602808445876 | LUAD | Female-baised eQTL |
| rs72745450 | chr5:29325825:T:C | - | 0.0527841471143135 | 0.0286221502960017 | LUAD | Female-baised eQTL |
| rs72745451 | chr5:29326077:A:T | - | 0.0527841471143135 | 0.0286221502960017 | LUAD | Female-baised eQTL |
| rs55696331 | chr5:29326710:T:G | - | 0.0527841471143135 | 0.0286221502960017 | LUAD | Female-baised eQTL |
| rs10073729 | chr5:29321647:C:A | - | 0.0514126852164093 | 0.0358632209515261 | LUAD | Female-baised eQTL |
| rs72745447 | chr5:29324770:G:C | - | 0.0514126852164093 | 0.0358632209515261 | LUAD | Female-baised eQTL |
| rs56148668 | chr5:34321505:A:C | - | -0.0362100284894104 | 0.0361216719767887 | LUAD | Female-baised eQTL |
| rs4481332 | chr5:34322959:G:A | - | -0.0362100284894104 | 0.0361216719767887 | LUAD | Female-baised eQTL |
| rs4484403 | chr5:34323013:G:A | - | -0.0362100284894104 | 0.0361216719767887 | LUAD | Female-baised eQTL |
| rs6863604 | chr5:34325565:G:T | - | -0.0361168635862178 | 0.0380569673168571 | LUAD | Female-baised eQTL |
| rs72745434 | chr5:29312621:G:A | - | 0.0512969681178814 | 0.038455597173211 | LUAD | Female-baised eQTL |
| rs13172053 | chr5:34336628:G:C | - | -0.0357972392687413 | 0.0391594080506549 | LUAD | Female-baised eQTL |
| rs11958379 | chr5:34342510:G:A | - | -0.0357696522432008 | 0.0394589902185043 | LUAD | Female-baised eQTL |
| rs62366467 | chr5:34342694:T:C | - | -0.0357696522432008 | 0.0394589902185043 | LUAD | Female-baised eQTL |
| rs6870262 | chr5:34344297:C:T | - | -0.0357696522432008 | 0.0394589902185043 | LUAD | Female-baised eQTL |
| rs10077074 | chr5:29328189:G:A | - | 0.0506253613533914 | 0.0405193735741825 | LUAD | Female-baised eQTL |
| rs12517740 | chr5:34326690:C:A | - | -0.035604482011203 | 0.0414028591950834 | LUAD | Female-baised eQTL |
| rs6451065 | chr5:34323263:T:C | - | -0.0355716078276819 | 0.0417720672488124 | LUAD | Female-baised eQTL |
| rs58962097 | chr5:34324989:G:C | - | -0.0355716078276819 | 0.0417720672488124 | LUAD | Female-baised eQTL |
| rs60282470 | chr5:34325065:G:T | - | -0.0355716078276819 | 0.0417720672488124 | LUAD | Female-baised eQTL |
| rs6862683 | chr5:34325342:A:G | - | -0.0355716078276819 | 0.0417720672488124 | LUAD | Female-baised eQTL |
| rs7726646 | chr5:34347244:A:G | - | -0.0353275832159324 | 0.0458806224130458 | LUAD | Female-baised eQTL |
| rs13165457 | chr5:34327872:A:G | - | -0.0350131458163561 | 0.0499083659647456 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs200111279 | chr5:30830032:A:T | - | 0.0538582590374803 | 0.027207783544395 | KIRC | Male-baised eQTL |
| rs73090429 | chr5:30830300:C:G | - | 0.0536558261253068 | 0.0285114279179491 | KIRC | Male-baised eQTL |
| rs73088490 | chr5:30814261:T:A | - | 0.0538103425618967 | 0.0377817014588411 | KIRC | Male-baised eQTL |
| rs12520777 | chr5:30813622:A:T | - | 0.0537488369115005 | 0.0381641099309942 | KIRC | Male-baised eQTL |
| rs73088495 | chr5:30815625:T:G | - | 0.0537488369115005 | 0.0381641099309942 | KIRC | Male-baised eQTL |
| rs148728588 | chr5:30822927:C:T | - | 0.0541266849129309 | 0.0417810169586098 | KIRC | Male-baised eQTL |
| rs144681819 | chr5:30822949:C:G | - | 0.0541266849129309 | 0.0417810169586098 | KIRC | Male-baised eQTL |
| rs4401585 | chr5:30823748:C:T | - | 0.0541266849129309 | 0.0417810169586098 | KIRC | Male-baised eQTL |
| rs4518414 | chr5:30823937:C:T | - | 0.0541266849129309 | 0.0417810169586098 | KIRC | Male-baised eQTL |
| rs75252885 | chr5:30828103:C:A | - | 0.0541266849129309 | 0.0417810169586098 | KIRC | Male-baised eQTL |
| rs9292748 | chr5:39701817:A:C | - | -0.0534474415535606 | 0.0454959404097424 | KIRC | Male-baised eQTL |
| rs60370290 | chr5:30816342:C:G | - | 0.0514888922825366 | 0.0477981133433732 | KIRC | Male-baised eQTL |
| rs200712793 | chr5:30821324:T:C | - | 0.0539179227160127 | 0.0484526284349891 | KIRC | Male-baised eQTL |
| rs111697264 | chr5:30586954:C:A | - | 0.148269739601201 | 3.51693297564391e-14 | BLCA | Male-baised eQTL |
| rs112062055 | chr5:30621675:A:T | - | 0.100662648431225 | 9.37805095491531e-09 | BLCA | Male-baised eQTL |
| rs73084550 | chr5:30607825:G:A | - | 0.0980195246606523 | 2.00097846826136e-08 | BLCA | Male-baised eQTL |
| rs16899707 | chr5:30629008:T:A | - | 0.088532201401976 | 1.98939670245108e-07 | BLCA | Male-baised eQTL |
| rs62355519 | chr5:35183046:C:T | - | 0.0884980177463044 | 0.00165940109902878 | BLCA | Male-baised eQTL |
| rs72740668 | chr5:27181144:C:A | - | 0.0472244368602959 | 0.00171091928534259 | BLCA | Male-baised eQTL |
| rs72740669 | chr5:27181650:C:T | - | 0.0465808617229818 | 0.00194544371010408 | BLCA | Male-baised eQTL |
| rs61673971 | chr5:27182573:T:A | - | 0.0464079287951646 | 0.00205375349895751 | BLCA | Male-baised eQTL |
| rs56954447 | chr5:27182668:G:C | - | 0.0464079287951646 | 0.00205375349895751 | BLCA | Male-baised eQTL |
| rs111689389 | chr5:27175855:G:C | - | 0.0464198326431287 | 0.00216621937216083 | BLCA | Male-baised eQTL |
| rs72739242 | chr5:27176206:T:C | - | 0.0464198326431287 | 0.00216621937216083 | BLCA | Male-baised eQTL |
| rs72739243 | chr5:27176513:T:C | - | 0.0464198326431287 | 0.00216621937216083 | BLCA | Male-baised eQTL |
| rs76616501 | chr5:27177518:T:C | - | 0.0464198326431287 | 0.00216621937216083 | BLCA | Male-baised eQTL |
| rs78162573 | chr5:27177530:C:T | - | 0.0464198326431287 | 0.00216621937216083 | BLCA | Male-baised eQTL |
| rs72740664 | chr5:27179179:T:G | - | 0.0464198326431287 | 0.00216621937216083 | BLCA | Male-baised eQTL |
| rs72740666 | chr5:27179262:C:T | - | 0.0464198326431287 | 0.00216621937216083 | BLCA | Male-baised eQTL |
| rs72740674 | chr5:27183200:T:A | - | 0.0460320432023673 | 0.00226386728142921 | BLCA | Male-baised eQTL |
| rs72740682 | chr5:27184705:A:G | - | 0.0461996740337187 | 0.0023322642136743 | BLCA | Male-baised eQTL |
| rs72740686 | chr5:27185363:G:A | - | 0.0461996740337187 | 0.0023322642136743 | BLCA | Male-baised eQTL |
| rs4496679 | chr5:27185774:A:G | - | 0.0461996740337187 | 0.0023322642136743 | BLCA | Male-baised eQTL |
| rs4429813 | chr5:27186058:A:C | - | 0.0461996740337187 | 0.0023322642136743 | BLCA | Male-baised eQTL |
| rs72740683 | chr5:27184851:G:A | - | 0.0461938542573394 | 0.00233396855066526 | BLCA | Male-baised eQTL |
| rs111497162 | chr5:27174533:T:C | - | 0.0463181815314192 | 0.00239962565573249 | BLCA | Male-baised eQTL |
| rs72740675 | chr5:27183383:T:A | - | 0.0458113627965437 | 0.00243637425325221 | BLCA | Male-baised eQTL |
| rs72740677 | chr5:27183454:T:A | - | 0.0458113627965437 | 0.00243637425325221 | BLCA | Male-baised eQTL |
| rs72740690 | chr5:27186536:T:A | - | 0.0462045221744755 | 0.00246812462771417 | BLCA | Male-baised eQTL |
| rs72740691 | chr5:27187030:A:G | - | 0.0462045221744755 | 0.00246812462771417 | BLCA | Male-baised eQTL |
| rs72740692 | chr5:27187787:A:T | - | 0.0462045221744755 | 0.00246812462771417 | BLCA | Male-baised eQTL |
| rs72740693 | chr5:27187981:T:A | - | 0.0462045221744755 | 0.00246812462771417 | BLCA | Male-baised eQTL |
| rs72740694 | chr5:27187984:C:T | - | 0.0462045221744755 | 0.00246812462771417 | BLCA | Male-baised eQTL |
| rs72739238 | chr5:27174979:G:A | - | 0.0460355190274863 | 0.00258846851297953 | BLCA | Male-baised eQTL |
| rs72739239 | chr5:27175226:G:T | - | 0.0460355190274863 | 0.00258846851297953 | BLCA | Male-baised eQTL |
| rs72739240 | chr5:27175477:C:T | - | 0.0460355190274863 | 0.00258846851297953 | BLCA | Male-baised eQTL |
| rs79870872 | chr5:27184005:A:T | - | 0.0455913136431283 | 0.00261954752945706 | BLCA | Male-baised eQTL |
| rs72740679 | chr5:27184043:C:T | - | 0.0455913136431283 | 0.00261954752945706 | BLCA | Male-baised eQTL |
| rs72740681 | chr5:27184416:A:T | - | 0.0455913136431283 | 0.00261954752945706 | BLCA | Male-baised eQTL |
| rs4518345 | chr5:27185797:G:A | - | 0.0457673385045558 | 0.00268098893947598 | BLCA | Male-baised eQTL |
| rs7723205 | chr5:27182144:T:A | - | 0.0457790058089189 | 0.00286312653800458 | BLCA | Male-baised eQTL |
| rs62355516 | chr5:35175097:A:C | - | 0.0835691402483986 | 0.00331273763783157 | BLCA | Male-baised eQTL |
| rs72740696 | chr5:27188528:A:G | - | 0.04498754482629 | 0.00340166955357132 | BLCA | Male-baised eQTL |
| rs72740698 | chr5:27188709:A:G | - | 0.04498754482629 | 0.00340166955357132 | BLCA | Male-baised eQTL |
| rs72740699 | chr5:27188711:G:C | - | 0.04498754482629 | 0.00340166955357132 | BLCA | Male-baised eQTL |
| rs72740701 | chr5:27188769:A:G | - | 0.04498754482629 | 0.00340166955357132 | BLCA | Male-baised eQTL |
| rs72742703 | chr5:27188799:C:A | - | 0.04498754482629 | 0.00340166955357132 | BLCA | Male-baised eQTL |
| rs4640754 | chr5:27186026:T:A | - | 0.0451987320840431 | 0.00355307025874245 | BLCA | Male-baised eQTL |
| rs7701777 | chr5:27178065:T:G | - | 0.0445575379632676 | 0.00407956864693408 | BLCA | Male-baised eQTL |
| rs57219996 | chr5:27180058:T:G | - | 0.0440286087924596 | 0.00426286315488273 | BLCA | Male-baised eQTL |
| rs72742706 | chr5:27189403:C:T | - | 0.0436635759721083 | 0.00471545725706456 | BLCA | Male-baised eQTL |
| rs4510545 | chr5:27189243:A:C | - | 0.0428464745364692 | 0.00495917250510161 | BLCA | Male-baised eQTL |
| rs13154399 | chr5:24528503:G:T | - | 0.0401769973661205 | 0.00879262121097157 | BLCA | Male-baised eQTL |
| rs17518542 | chr5:24524981:G:T | - | 0.0401222652291359 | 0.00888142334957135 | BLCA | Male-baised eQTL |
| rs78066187 | chr5:29339742:G:C | - | 0.0871031025693266 | 0.00919892027902174 | BLCA | Male-baised eQTL |
| rs62360567 | chr5:41387312:G:A | - | 0.0853673172809721 | 0.0110599333426306 | BLCA | Male-baised eQTL |
| rs62360570 | chr5:41396717:A:G | - | 0.0853673172809721 | 0.0110599333426306 | BLCA | Male-baised eQTL |
| rs6886261 | chr5:43022662:T:C | - | 0.0704514720266209 | 0.013900970082687 | BLCA | Male-baised eQTL |
| rs10941071 | chr5:33612230:C:T | - | 0.0407390775085696 | 0.0151204176071918 | BLCA | Male-baised eQTL |
| rs10521006 | chr5:33602786:G:C | - | 0.0404987730188502 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs67558897 | chr5:33791984:G:A | - | 0.0713951854710241 | 0.0157748276322832 | BLCA | Male-baised eQTL |
| rs73748736 | chr5:29298711:G:A | - | 0.0444237974554503 | 0.0172437474037835 | BLCA | Male-baised eQTL |
| rs76024075 | chr5:29283701:A:G | - | 0.043765555584465 | 0.0202828304366373 | BLCA | Male-baised eQTL |
| rs73748729 | chr5:29284789:T:C | - | 0.043765555584465 | 0.0202828304366373 | BLCA | Male-baised eQTL |
| rs73748730 | chr5:29285647:G:A | - | 0.043765555584465 | 0.0202828304366373 | BLCA | Male-baised eQTL |
| rs76972819 | chr5:29291967:T:C | - | 0.043765555584465 | 0.0202828304366373 | BLCA | Male-baised eQTL |
| rs73748734 | chr5:29294132:T:G | - | 0.043765555584465 | 0.0202828304366373 | BLCA | Male-baised eQTL |
| rs6865945 | chr5:29304948:A:C | - | 0.0431582745565498 | 0.0221462526218325 | BLCA | Male-baised eQTL |
| rs6867418 | chr5:29329865:C:T | - | 0.0429446267131757 | 0.0225739631567634 | BLCA | Male-baised eQTL |
| rs55740609 | chr5:29320455:C:T | - | 0.0428704681778382 | 0.0230467741865788 | BLCA | Male-baised eQTL |
| rs73751136 | chr5:29310413:C:G | - | 0.0427137764624465 | 0.0245432422105267 | BLCA | Male-baised eQTL |
| rs10940791 | chr5:29315160:T:G | - | 0.0425677717778531 | 0.0245710661874199 | BLCA | Male-baised eQTL |
| rs13164467 | chr5:33745777:G:C | - | 0.0658343913646868 | 0.0276575360372099 | BLCA | Male-baised eQTL |
| rs7736040 | chr5:29270405:G:A | - | 0.0417978540933634 | 0.0298448024836335 | BLCA | Male-baised eQTL |
| rs80320637 | chr5:29271380:A:G | - | 0.0417978540933634 | 0.0298448024836335 | BLCA | Male-baised eQTL |
| rs73081304 | chr5:29466557:A:T | - | 0.0731662831946012 | 0.0299146964508245 | BLCA | Male-baised eQTL |
| rs1014525 | chr5:33748437:C:T | - | -0.0401804748938886 | 0.0306359409820874 | BLCA | Male-baised eQTL |
| rs1549258 | chr5:33748495:C:T | - | -0.0401804748938886 | 0.0306359409820874 | BLCA | Male-baised eQTL |
| rs6882380 | chr5:42921599:T:A | - | 0.063164987248899 | 0.0308288424787628 | BLCA | Male-baised eQTL |
| rs6883962 | chr5:31124831:C:T | - | 0.0699044759393104 | 0.0308824078749768 | BLCA | Male-baised eQTL |
| rs72747757 | chr5:31127214:G:T | - | 0.0699044759393104 | 0.0308824078749768 | BLCA | Male-baised eQTL |
| rs72747745 | chr5:31111824:G:A | - | 0.0698945931849889 | 0.031020837898272 | BLCA | Male-baised eQTL |
| rs6895637 | chr5:33749707:T:G | - | -0.03992096570788 | 0.0328438352903962 | BLCA | Male-baised eQTL |
| rs1423481 | chr5:33750248:T:C | - | -0.03992096570788 | 0.0328438352903962 | BLCA | Male-baised eQTL |
| rs68189045 | chr5:31165923:C:T | - | 0.0681374240183873 | 0.0328476764739449 | BLCA | Male-baised eQTL |
| rs10940870 | chr5:30093477:T:C | - | 0.0376074637706609 | 0.0351832698955607 | BLCA | Male-baised eQTL |
| rs75900346 | chr5:26150914:A:G | - | 0.0657447170267988 | 0.0360975785405663 | BLCA | Male-baised eQTL |
| rs116481463 | chr5:26151357:G:C | - | 0.0657447170267988 | 0.0360975785405663 | BLCA | Male-baised eQTL |
| rs76254332 | chr5:26151777:T:C | - | 0.0657447170267988 | 0.0360975785405663 | BLCA | Male-baised eQTL |
| rs114546633 | chr5:26153158:T:C | - | 0.0657447170267988 | 0.0360975785405663 | BLCA | Male-baised eQTL |
| rs66868236 | chr5:33784776:C:T | - | 0.0635017891305287 | 0.0373809579258416 | BLCA | Male-baised eQTL |
| rs13162619 | chr5:33799375:T:C | - | 0.0632369961884545 | 0.0387731639194834 | BLCA | Male-baised eQTL |
| rs10040180 | chr5:37795905:C:T | - | 0.0390069248551573 | 0.039783367114986 | BLCA | Male-baised eQTL |
| rs10473068 | chr5:37792980:C:G | - | 0.0389227216981773 | 0.040691884584329 | BLCA | Male-baised eQTL |
| rs79481553 | chr5:26166294:A:T | - | 0.0641016112639066 | 0.0427590105080173 | BLCA | Male-baised eQTL |
| rs75055674 | chr5:26167267:T:A | - | 0.0641016112639066 | 0.0427590105080173 | BLCA | Male-baised eQTL |
| rs376509481 | chr5:26167456:C:T | - | 0.0641016112639066 | 0.0427590105080173 | BLCA | Male-baised eQTL |
| rs76225778 | chr5:29220524:T:A | - | 0.0693473955533542 | 0.0427706558527252 | BLCA | Male-baised eQTL |
| rs74669472 | chr5:26155112:G:T | - | 0.0640794761221389 | 0.0427828351464506 | BLCA | Male-baised eQTL |
| rs75540710 | chr5:26155847:C:T | - | 0.0640794761221389 | 0.0427828351464506 | BLCA | Male-baised eQTL |
| rs75470706 | chr5:26156419:T:C | - | 0.0640794761221389 | 0.0427828351464506 | BLCA | Male-baised eQTL |
| rs10064222 | chr5:37795943:C:T | - | 0.0386909238717983 | 0.042820415089724 | BLCA | Male-baised eQTL |
| rs10064567 | chr5:37796328:G:A | - | 0.0386909238717983 | 0.042820415089724 | BLCA | Male-baised eQTL |
| rs75698187 | chr5:26160261:G:A | - | 0.0640652204293464 | 0.0428787882619469 | BLCA | Male-baised eQTL |
| rs79983149 | chr5:26162766:A:G | - | 0.0640652204293464 | 0.0428787882619469 | BLCA | Male-baised eQTL |
| rs77046183 | chr5:26163331:G:A | - | 0.0640652204293464 | 0.0428787882619469 | BLCA | Male-baised eQTL |
| rs11954990 | chr5:26039157:G:C | - | 0.0334123935815196 | 0.0433251588826589 | BLCA | Male-baised eQTL |
| rs76704491 | chr5:26157532:G:T | - | 0.0639895122829032 | 0.0434658834437709 | BLCA | Male-baised eQTL |
| rs4701529 | chr5:26158250:C:A | - | 0.0639895122829032 | 0.0434658834437709 | BLCA | Male-baised eQTL |
| rs4701262 | chr5:26158485:A:G | - | 0.0639895122829032 | 0.0434658834437709 | BLCA | Male-baised eQTL |
| rs9292673 | chr5:37791631:A:G | - | 0.0385965087011213 | 0.0435303951768228 | BLCA | Male-baised eQTL |
| rs10063743 | chr5:37792066:T:C | - | 0.0385965087011213 | 0.0435303951768228 | BLCA | Male-baised eQTL |
| rs114340740 | chr5:26154207:G:T | - | 0.0632605350452249 | 0.0446722219071291 | BLCA | Male-baised eQTL |
| rs10071470 | chr5:42921827:T:G | - | 0.0591555030191627 | 0.0447574246156846 | BLCA | Male-baised eQTL |
| rs75076501 | chr5:26173884:A:G | - | 0.0625073141893307 | 0.0466880910242667 | BLCA | Male-baised eQTL |
| rs76015154 | chr5:26173998:A:G | - | 0.0625073141893307 | 0.0466880910242667 | BLCA | Male-baised eQTL |
| rs10066877 | chr5:26015819:C:A | - | 0.0348766022979582 | 0.047643788505835 | BLCA | Male-baised eQTL |
| rs74347713 | chr5:29902035:G:A | - | 0.0372958907018375 | 0.0477785367081977 | BLCA | Male-baised eQTL |
| rs10039678 | chr5:26031864:G:T | - | 0.0344837892184027 | 0.0478069349299118 | BLCA | Male-baised eQTL |
| rs74383848 | chr5:26176071:C:T | - | 0.0622880180870979 | 0.0481315348324586 | BLCA | Male-baised eQTL |
| rs77993994 | chr5:26176284:T:C | - | 0.0622880180870979 | 0.0481315348324586 | BLCA | Male-baised eQTL |
| rs79496943 | chr5:26179386:G:C | - | 0.0622880180870979 | 0.0481315348324586 | BLCA | Male-baised eQTL |
| rs10044831 | chr5:31162258:A:G | - | 0.0642947849504926 | 0.0487258292858733 | BLCA | Male-baised eQTL |
| rs10036316 | chr5:26017262:G:A | - | 0.0344265925021593 | 0.0493164260718749 | BLCA | Male-baised eQTL |
| rs10071534 | chr5:42921971:T:C | - | 0.0581001277075464 | 0.0493947722966433 | BLCA | Male-baised eQTL |
| rs6894480 | chr5:32632192:C:T | - | 0.044895500552212 | 0.0217390141352643 | LUAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
 | EX ID: exon_skip_441413 |
| SNP ID: rs12653362 | |
| SNP Position to ES: Distant upstream | |
| Male Effect: - | |
| Female Effect: -0.117656344688322 |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs12653362 | chr5:34564705:A:G | Distant upstream | -0.117656344688322 | 7.22802704202321e-05 | LUAD | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs73081172 | chr5:34552179:G:A | Distant upstream | -0.091137409809649 | 0.01314952890461 | LUAD | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs28436808 | chr5:34550751:C:T | Distant upstream | -0.0913577479874929 | 0.0157619583306012 | LUAD | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs16902849 | chr5:34552092:T:A | Distant upstream | -0.0913577479874929 | 0.0157619583306012 | LUAD | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs6878220 | chr5:34553650:A:G | Distant upstream | -0.0913577479874929 | 0.0157619583306012 | LUAD | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs13436817 | chr5:34554476:A:G | Distant upstream | -0.0913577479874929 | 0.0157619583306012 | LUAD | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs13436782 | chr5:34557141:T:C | Distant upstream | -0.0913577479874929 | 0.0157619583306012 | LUAD | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs6859723 | chr5:34555639:G:A | Distant upstream | -0.0887443468592383 | 0.0192308218198688 | LUAD | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs4400102 | chr5:34547300:G:C | Distant upstream | 0.0874559460327486 | 0.0229923773884397 | LUAD | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs42868 | chr5:33935971:C:G | Distant downstream | -0.062922522914886 | 0.0399622052445418 | HNSC | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs268716 | chr5:33352373:T:C | Distant downstream | 0.0446372594568005 | 0.0235583870870484 | COAD | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs268717 | chr5:33352632:C:T | Distant downstream | 0.0446372594568005 | 0.0235583870870484 | COAD | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs268719 | chr5:33353468:C:G | Distant downstream | 0.0446372594568005 | 0.0235583870870484 | COAD | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs272750 | chr5:33345974:T:G | Distant downstream | 0.0438910874049359 | 0.0279503755819073 | COAD | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs268723 | chr5:33355167:T:C | Distant downstream | 0.0438910874049359 | 0.0279503755819073 | COAD | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs2916184 | chr5:33253479:A:G | Distant downstream | 0.0510503260891441 | 0.0485125947984873 | COAD | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs1072516 | chr5:34604810:G:A | Distant upstream | -0.103702703680335 | 0.00652709458533849 | BLCA | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs10035360 | chr5:34604531:C:T | Distant upstream | -0.0975650021519834 | 0.0405706546856745 | BLCA | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs73076500 | chr5:34758617:G:A | Distant upstream | -0.0907762935101859 | 0.0200636385164752 | KIRP | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs73078604 | chr5:34759791:T:G | Distant upstream | -0.0907762935101859 | 0.0200636385164752 | KIRP | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs76004315 | chr5:34761257:G:T | Distant upstream | -0.0907762935101859 | 0.0200636385164752 | KIRP | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs61083416 | chr5:34763574:A:G | Distant upstream | -0.0907762935101859 | 0.0200636385164752 | KIRP | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs28810178 | chr5:33054451:G:T | Distant downstream | -0.0555686942921703 | 0.0282997144501153 | KIRP | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs10069546 | chr5:33058006:G:A | Distant downstream | -0.0584405559725228 | 0.033042687988808 | KIRP | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs10074451 | chr5:33055574:C:T | Distant downstream | -0.054684707498986 | 0.0332906097426576 | KIRP | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs10074513 | chr5:33055636:C:T | Distant downstream | -0.054684707498986 | 0.0332906097426576 | KIRP | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs28685037 | chr5:33050911:G:A | Distant downstream | -0.0548585460563495 | 0.0350993502771332 | KIRP | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs10075576 | chr5:33051856:T:C | Distant downstream | -0.0548585460563495 | 0.0350993502771332 | KIRP | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs10070007 | chr5:33052987:C:G | Distant downstream | -0.0548585460563495 | 0.0350993502771332 | KIRP | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs1582920 | chr5:33053813:A:C | Distant downstream | -0.0548585460563495 | 0.0350993502771332 | KIRP | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs7737718 | chr5:33057126:G:T | Distant downstream | -0.0585799861180114 | 0.0360075054756541 | KIRP | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs7719615 | chr5:33057130:T:G | Distant downstream | -0.0585799861180114 | 0.0360075054756541 | KIRP | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs7737482 | chr5:33057169:C:T | Distant downstream | -0.0585799861180114 | 0.0360075054756541 | KIRP | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs13362102 | chr5:33050088:A:G | Distant downstream | -0.053979424646027 | 0.0398325639436518 | KIRP | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs28472877 | chr5:33051032:C:A | Distant downstream | -0.053979424646027 | 0.0398325639436518 | KIRP | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs13354580 | chr5:33052309:A:C | Distant downstream | -0.053979424646027 | 0.0398325639436518 | KIRP | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs10068306 | chr5:33052687:C:A | Distant downstream | -0.053979424646027 | 0.0398325639436518 | KIRP | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs28819094 | chr5:33053289:C:T | Distant downstream | -0.053979424646027 | 0.0398325639436518 | KIRP | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs10072045 | chr5:33054047:C:T | Distant downstream | -0.053979424646027 | 0.0398325639436518 | KIRP | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs7736200 | chr5:34567262:G:C | Distant upstream | -0.0982378178577316 | 0.0296278059437872 | SARC | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs12697303 | chr5:34417714:T:C | Distant upstream | 0.149108197115385 | 0.0324598865883877 | SARC | Female-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs57745583 | chr5:34418330:G:A | Distant upstream | 0.149108197115385 | 0.0324598865883877 | SARC | Female-baised sQTL |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs3849683 | chr5:33441740:C:A | Distant downstream | -0.0473453875427422 | 0.00331939186108237 | KIRC | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs3756661 | chr5:33440704:T:G | Distant downstream | -0.0340392763895964 | 0.0182886597574389 | KIRC | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs6888749 | chr5:33435544:T:C | Distant downstream | -0.0334387551925055 | 0.0219988725820167 | KIRC | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs7708805 | chr5:33430094:A:G | Distant downstream | -0.0325180685599739 | 0.0236416794861924 | KIRC | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs16891141 | chr5:33442972:C:G | Distant downstream | -0.0465588115352956 | 0.0245249800550085 | KIRC | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs4867511 | chr5:33437237:C:T | Distant downstream | -0.0331275309788712 | 0.0250652741060052 | KIRC | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs1438728 | chr5:33433896:G:A | Distant downstream | -0.0327407877252513 | 0.0289657827540087 | KIRC | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs6892154 | chr5:33427271:G:C | Distant downstream | -0.0321192205144376 | 0.0352866997288517 | KIRC | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs12655535 | chr5:33428944:A:G | Distant downstream | -0.0321192205144376 | 0.0352866997288517 | KIRC | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs268735 | chr5:33376094:C:G | Distant downstream | 0.0839996187448929 | 0.00464889413109312 | LUAD | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs155586 | chr5:33380086:T:C | Distant downstream | 0.0839996187448929 | 0.00464889413109312 | LUAD | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs156319 | chr5:33399094:T:C | Distant downstream | 0.0655511458190864 | 0.0450418976448716 | LUAD | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs13356779 | chr5:34559070:G:A | Distant upstream | -0.0397500623567048 | 0.0112039474785319 | HNSC | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs10213909 | chr5:33038291:G:A | Distant downstream | 0.0423512893179744 | 0.0127855607205407 | HNSC | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs1816237 | chr5:33040706:C:T | Distant downstream | 0.0380772014053144 | 0.0386315991316535 | HNSC | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs2113110 | chr5:33885410:G:A | Distant downstream | 0.0285538828849113 | 0.0275556933488688 | LIHC | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs35176895 | chr5:34930282:T:C | Distant upstream | 0.0294485128564184 | 0.027698822319703 | LIHC | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs11956668 | chr5:34965160:G:A | Distant upstream | 0.0291784000482703 | 0.0280903167889291 | LIHC | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs4866399 | chr5:33887314:G:A | Distant downstream | 0.0278866195046224 | 0.0344037677195154 | LIHC | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs67450756 | chr5:33444346:A:C | Distant downstream | -0.0324552417939746 | 0.0100218113589458 | KIRP | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs7708805 | chr5:33430094:A:G | Distant downstream | -0.0320641340524942 | 0.0147323508839681 | KIRP | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs6870410 | chr5:33417989:G:T | Distant downstream | -0.0330392561959701 | 0.017233614619265 | KIRP | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs3756661 | chr5:33440704:T:G | Distant downstream | -0.0305755716102584 | 0.026639842829475 | KIRP | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs6888749 | chr5:33435544:T:C | Distant downstream | -0.0306190586911957 | 0.0268112911081164 | KIRP | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs6892154 | chr5:33427271:G:C | Distant downstream | -0.0299942578650726 | 0.0351805241538425 | KIRP | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs12655535 | chr5:33428944:A:G | Distant downstream | -0.0299942578650726 | 0.0351805241538425 | KIRP | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs3765145 | chr5:33458531:G:A | Distant downstream | -0.0271687868221149 | 0.0421856770765823 | KIRP | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs6879430 | chr5:33422797:T:C | Distant downstream | -0.0269306503189482 | 0.0442115982664493 | KIRP | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs6450988 | chr5:33424101:G:C | Distant downstream | -0.0269306503189482 | 0.0442115982664493 | KIRP | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs6874199 | chr5:33424048:A:G | Distant downstream | -0.0269270943216572 | 0.0443295079494045 | KIRP | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs2331212 | chr5:33422354:C:T | Distant downstream | -0.0267995736771975 | 0.0450259522404764 | KIRP | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs6880451 | chr5:33425263:C:T | Distant downstream | -0.0267995736771975 | 0.0450259522404764 | KIRP | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs1542031 | chr5:33431247:C:T | Distant downstream | -0.0267302791486613 | 0.0463131027164829 | KIRP | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs6860798 | chr5:33432165:T:A | Distant downstream | -0.0267302791486613 | 0.0463131027164829 | KIRP | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs3777083 | chr5:33442018:A:G | Distant downstream | -0.0291321750245221 | 0.0466132380054433 | KIRP | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs3777082 | chr5:33442159:G:A | Distant downstream | -0.0291321750245221 | 0.0466132380054433 | KIRP | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs6866808 | chr5:33442430:C:A | Distant downstream | -0.0291321750245221 | 0.0466132380054433 | KIRP | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs6450986 | chr5:33420892:C:T | Distant downstream | -0.0266656986681708 | 0.0474396593152015 | KIRP | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs2118721 | chr5:33421152:C:T | Distant downstream | -0.0266656986681708 | 0.0474396593152015 | KIRP | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs2118720 | chr5:33421174:T:C | Distant downstream | -0.0266656986681708 | 0.0474396593152015 | KIRP | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs1438728 | chr5:33433896:G:A | Distant downstream | -0.028964416175477 | 0.0499375336967232 | KIRP | Male-baised sQTL |
| exon_skip_441413 | chr5:34004573:34004734 | Frame-shift | rs4867511 | chr5:33437237:C:T | Distant downstream | -0.028964416175477 | 0.0499375336967232 | KIRP | Male-baised sQTL |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of AMACR |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000242110 | AMACR | C0001430 | Adenoma | 1 | CTD_human |
| ENSG00000242110 | AMACR | C0009402 | Colorectal Carcinoma | 1 | CTD_human |
| ENSG00000242110 | AMACR | C0009404 | Colorectal Neoplasms | 1 | CTD_human |
| ENSG00000242110 | AMACR | C0011195 | Dejerine-Sottas Disease (disorder) | 1 | CTD_human |
| ENSG00000242110 | AMACR | C0019816 | Hereditary, Type VII, Motor and Sensory Neuropathy | 1 | CTD_human |
| ENSG00000242110 | AMACR | C0023893 | Liver Cirrhosis, Experimental | 2 | CTD_human |
| ENSG00000242110 | AMACR | C0023895 | Liver diseases | 1 | CTD_human |
| ENSG00000242110 | AMACR | C0027888 | Hereditary Motor and Sensory Neuropathies | 1 | CTD_human |
| ENSG00000242110 | AMACR | C0033578 | Prostatic Neoplasms | 3 | CTD_human |
| ENSG00000242110 | AMACR | C0036341 | Schizophrenia | 1 | PSYGENET |
| ENSG00000242110 | AMACR | C0086565 | Liver Dysfunction | 1 | CTD_human |
| ENSG00000242110 | AMACR | C0205646 | Adenoma, Basal Cell | 1 | CTD_human |
| ENSG00000242110 | AMACR | C0205647 | Follicular adenoma | 1 | CTD_human |
| ENSG00000242110 | AMACR | C0205648 | Adenoma, Microcystic | 1 | CTD_human |
| ENSG00000242110 | AMACR | C0205649 | Adenoma, Monomorphic | 1 | CTD_human |
| ENSG00000242110 | AMACR | C0205650 | Papillary adenoma | 1 | CTD_human |
| ENSG00000242110 | AMACR | C0205651 | Adenoma, Trabecular | 1 | CTD_human |
| ENSG00000242110 | AMACR | C0376358 | Malignant neoplasm of prostate | 3 | CTD_human |
| ENSG00000242110 | AMACR | C1858328 | Bile acid synthesis defect, congenital, 4 | 1 | CTD_human |
| ENSG00000242110 | AMACR | C3280428 | Alpha-Methylacyl-CoA Racemase Deficiency | 1 | CTD_human |
