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Gene: ENSG00000235162 |
Summary for C12orf75 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000235162 | Gene symbol | C12orf75 |
| Gene name | chromosome 12 open reading frame 75 | |
| HGNC | 35164 | |
| Entrez ID | 387882 | |
| Gene type | protein_coding | |
| Synonyms | C12orf75|OCC-1|OCC1|AGD3 | |
| UniProtAcc | Q8TAD7 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for C12orf75 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| C12orf75 | 3.11e+02 | 1.24e+00 | 2.94e-01 | 4.22e+00 | 2.49e-05 | 1.02e-04 | THCA |
| C12orf75 | 1.02e+03 | 2.19e+00 | 5.30e-01 | 4.14e+00 | 3.53e-05 | 1.80e-04 | BLCA |
| C12orf75 | 6.10e+03 | 1.39e+00 | 1.73e-01 | 8.01e+00 | 1.12e-15 | 1.42e-14 | KIRP |
| C12orf75 | 1.91e+03 | 1.06e+00 | 1.58e-01 | 6.69e+00 | 2.19e-11 | 1.60e-10 | COAD |
| C12orf75 | 2.74e+03 | 4.50e+00 | 7.07e-01 | 6.36e+00 | 2.08e-10 | 3.37e-09 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for C12orf75 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for C12orf75 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| MESO | cg21605781 | chr12:105236942 | CGI:chr12:105235719-105236321 | promoter,gene body | 3.01e-01 | 4.24e-01 | -2.48e+00 | 1.33e-02 | 3.28e-02 | -1.23e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| HNSC | cg21605781 | chr12:105236942 | CGI:chr12:105235719-105236321 | promoter,gene body | 2.65e-01 | 3.65e-01 | -4.20e+00 | 2.65e-05 | 8.52e-05 | -1.00e-01 |
| LUSC | cg21605781 | chr12:105236942 | CGI:chr12:105235719-105236321 | promoter,gene body | 2.45e-01 | 4.65e-01 | -4.27e+00 | 1.98e-05 | 5.26e-04 | -2.20e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
Top |
Exon skipping events with PSI in TCGA for C12orf75 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for C12orf75 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for C12orf75 |
| TFs related to C12orf75. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| PAAD | BPTF | C12orf75 | 4.16e+00 | 9.85e-01 | 3.11e+00 | 3.13e-03 | Male-biased |
| PAAD | DUX4 | C12orf75 | 4.61e+00 | 9.89e-01 | 3.63e+00 | 4.76e-03 | Male-biased |
| PAAD | ELF3 | C12orf75 | 3.88e+00 | 9.82e-01 | 2.37e+00 | 2.84e-04 | Male-biased |
| PAAD | FOXF1 | C12orf75 | 4.05e+00 | 9.86e-01 | 2.56e+00 | 3.10e-04 | Male-biased |
| PAAD | FOXI1 | C12orf75 | 4.28e+00 | 9.86e-01 | 3.29e+00 | 4.44e-03 | Male-biased |
| PAAD | FOXO1 | C12orf75 | 4.46e+00 | 9.91e-01 | 3.26e+00 | 1.54e-03 | Male-biased |
| PAAD | FOXO3 | C12orf75 | 4.60e+00 | 9.82e-01 | 3.80e+00 | 1.19e-02 | Male-biased |
| PAAD | FOXO4 | C12orf75 | 4.79e+00 | 9.91e-01 | 3.81e+00 | 4.90e-03 | Male-biased |
| PAAD | FOXO6 | C12orf75 | 4.50e+00 | 9.90e-01 | 3.43e+00 | 3.05e-03 | Male-biased |
| PAAD | FOXR2 | C12orf75 | 3.97e+00 | 9.85e-01 | 2.00e+00 | 1.92e-05 | Male-biased |
| PAAD | IRF7 | C12orf75 | 4.52e+00 | 9.83e-01 | 3.69e+00 | 1.04e-02 | Male-biased |
| PAAD | MEF2D | C12orf75 | 4.03e+00 | 9.85e-01 | 2.76e+00 | 1.01e-03 | Male-biased |
| PAAD | NEUROD1 | C12orf75 | 4.55e+00 | 9.89e-01 | 3.58e+00 | 4.81e-03 | Male-biased |
| PAAD | NFATC1 | C12orf75 | 4.41e+00 | 9.85e-01 | 3.52e+00 | 7.33e-03 | Male-biased |
| PAAD | NFATC2 | C12orf75 | 4.37e+00 | 9.86e-01 | 3.41e+00 | 5.18e-03 | Male-biased |
| PAAD | NKX3-2 | C12orf75 | 4.49e+00 | 9.92e-01 | 3.15e+00 | 7.29e-04 | Male-biased |
| PAAD | NR4A2 | C12orf75 | 4.42e+00 | 9.83e-01 | 3.57e+00 | 9.17e-03 | Male-biased |
| PAAD | POU2F2 | C12orf75 | 4.11e+00 | 9.87e-01 | 2.81e+00 | 8.53e-04 | Male-biased |
| PAAD | POU3F3 | C12orf75 | 4.15e+00 | 9.88e-01 | 2.38e+00 | 6.17e-05 | Male-biased |
| PAAD | POU5F1 | C12orf75 | 4.13e+00 | 9.87e-01 | 2.85e+00 | 9.60e-04 | Male-biased |
| PAAD | SOX7 | C12orf75 | 4.20e+00 | 9.89e-01 | 2.82e+00 | 5.88e-04 | Male-biased |
| PAAD | YY1 | C12orf75 | 3.98e+00 | 9.82e-01 | 2.92e+00 | 2.93e-03 | Male-biased |
| PAAD | ZIM3 | C12orf75 | 3.85e+00 | 9.81e-01 | 2.38e+00 | 3.47e-04 | Male-biased |
| PAAD | ZNF25 | C12orf75 | 4.01e+00 | 9.86e-01 | 2.10e+00 | 2.93e-05 | Male-biased |
| PAAD | ZNF317 | C12orf75 | 4.12e+00 | 9.85e-01 | 3.04e+00 | 2.82e-03 | Male-biased |
| PAAD | ZNF334 | C12orf75 | 4.25e+00 | 9.90e-01 | 1.95e+00 | 2.89e-06 | Male-biased |
| PAAD | ZNF418 | C12orf75 | 4.07e+00 | 9.87e-01 | 1.46e+00 | 7.00e-07 | Male-biased |
| PAAD | ZNF45 | C12orf75 | 3.99e+00 | 9.83e-01 | 2.82e+00 | 1.67e-03 | Male-biased |
| PAAD | ZNF584 | C12orf75 | 4.15e+00 | 9.88e-01 | 2.62e+00 | 2.49e-04 | Male-biased |
| PAAD | ZNF85 | C12orf75 | 4.11e+00 | 9.87e-01 | 2.79e+00 | 7.70e-04 | Male-biased |
| PAAD | ZNF879 | C12orf75 | 3.80e+00 | 9.80e-01 | 1.61e+00 | 4.97e-06 | Male-biased |
| PCPG | DNMT1 | C12orf75 | 3.17e+00 | 5.58e-03 | 4.09e+00 | 9.82e-01 | Female-biased |
| C12orf75 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for C12orf75 |
| RBPs related to ES in C12orf75. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| C12orf75 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs12315360 | chr12:101911590:C:T | - | 0.120949979270798 | 0.0178268495589566 | PCPG | Female-baised eQTL |
| rs12302035 | chr12:101911910:A:G | - | 0.120949979270798 | 0.0178268495589566 | PCPG | Female-baised eQTL |
| rs12297237 | chr12:101912059:T:C | - | 0.120949979270798 | 0.0178268495589566 | PCPG | Female-baised eQTL |
| rs12303480 | chr12:101912181:A:C | - | 0.120949979270798 | 0.0178268495589566 | PCPG | Female-baised eQTL |
| rs12297365 | chr12:101912261:T:C | - | 0.120949979270798 | 0.0178268495589566 | PCPG | Female-baised eQTL |
| rs12297551 | chr12:101912537:T:G | - | 0.120949979270798 | 0.0178268495589566 | PCPG | Female-baised eQTL |
| rs59097587 | chr12:101912800:T:C | - | 0.120949979270798 | 0.0178268495589566 | PCPG | Female-baised eQTL |
| rs76997354 | chr12:101913007:T:C | - | 0.120949979270798 | 0.0178268495589566 | PCPG | Female-baised eQTL |
| rs12319262 | chr12:101913657:G:T | - | 0.120949979270798 | 0.0178268495589566 | PCPG | Female-baised eQTL |
| rs57578776 | chr12:101913781:T:C | - | 0.120949979270798 | 0.0178268495589566 | PCPG | Female-baised eQTL |
| rs78919604 | chr12:101913933:G:A | - | 0.120949979270798 | 0.0178268495589566 | PCPG | Female-baised eQTL |
| rs78231972 | chr12:101910887:T:C | - | 0.120856631157483 | 0.0183283809909198 | PCPG | Female-baised eQTL |
| rs74241005 | chr12:101910958:A:G | - | 0.120856631157483 | 0.0183283809909198 | PCPG | Female-baised eQTL |
| rs78314569 | chr12:101911141:G:C | - | 0.120856631157483 | 0.0183283809909198 | PCPG | Female-baised eQTL |
| rs76086560 | chr12:101911212:A:G | - | 0.120856631157483 | 0.0183283809909198 | PCPG | Female-baised eQTL |
| rs60930790 | chr12:101914081:T:G | - | 0.120856631157483 | 0.0183283809909198 | PCPG | Female-baised eQTL |
| rs17023951 | chr12:95309638:G:C | - | 0.115047704235675 | 0.0289411957278453 | PCPG | Female-baised eQTL |
| rs73227451 | chr12:95309706:T:C | - | 0.115047704235675 | 0.0289411957278453 | PCPG | Female-baised eQTL |
| rs66511039 | chr12:95310513:G:T | - | 0.115047704235675 | 0.0289411957278453 | PCPG | Female-baised eQTL |
| rs17023960 | chr12:95310807:A:C | - | 0.115047704235675 | 0.0289411957278453 | PCPG | Female-baised eQTL |
| rs17023968 | chr12:95311756:A:C | - | 0.115047704235675 | 0.0289411957278453 | PCPG | Female-baised eQTL |
| rs61937954 | chr12:95236864:G:C | - | 0.110105529847115 | 0.0433508315029456 | PCPG | Female-baised eQTL |
| rs17023875 | chr12:95273067:T:C | - | 0.110105529847115 | 0.0433508315029456 | PCPG | Female-baised eQTL |
| rs7959433 | chr12:95277424:G:C | - | 0.110105529847115 | 0.0433508315029456 | PCPG | Female-baised eQTL |
| rs58559529 | chr12:95288075:C:A | - | 0.110105529847115 | 0.0433508315029456 | PCPG | Female-baised eQTL |
| rs61939803 | chr12:95305664:C:T | - | 0.110105529847115 | 0.0433508315029456 | PCPG | Female-baised eQTL |
| rs1732783 | chr12:113031336:T:C | - | -0.206352644241945 | 0.0433180722237332 | KIRP | Female-baised eQTL |
| rs1732781 | chr12:113033711:G:A | - | -0.206352644241945 | 0.0433180722237332 | KIRP | Female-baised eQTL |
| rs703658 | chr12:104655285:G:T | - | 0.124047772443336 | 0.00292109831185471 | LUSC | Female-baised eQTL |
| rs2694412 | chr12:104648746:G:A | - | 0.109884662730589 | 0.00451083042723015 | LUSC | Female-baised eQTL |
| rs2694416 | chr12:104646703:G:A | - | 0.105519773344179 | 0.00684697277141989 | LUSC | Female-baised eQTL |
| rs2694413 | chr12:104648412:G:C | - | 0.101918575019209 | 0.00964745094115875 | LUSC | Female-baised eQTL |
| rs2696002 | chr12:104648469:A:G | - | 0.101918575019209 | 0.00964745094115875 | LUSC | Female-baised eQTL |
| rs2559638 | chr12:104648566:T:C | - | 0.101918575019209 | 0.00964745094115875 | LUSC | Female-baised eQTL |
| rs2696001 | chr12:104648639:A:G | - | 0.101918575019209 | 0.00964745094115875 | LUSC | Female-baised eQTL |
| rs727862 | chr12:104649112:G:A | - | 0.101918575019209 | 0.00964745094115875 | LUSC | Female-baised eQTL |
| rs2694411 | chr12:104649960:T:C | - | 0.104310793701983 | 0.0233038190159994 | LUSC | Female-baised eQTL |
| rs2696000 | chr12:104650045:A:G | - | 0.104310793701983 | 0.0233038190159994 | LUSC | Female-baised eQTL |
| rs2695999 | chr12:104650145:A:G | - | 0.104310793701983 | 0.0233038190159994 | LUSC | Female-baised eQTL |
| rs2695998 | chr12:104650511:A:G | - | 0.104310793701983 | 0.0233038190159994 | LUSC | Female-baised eQTL |
| rs2694410 | chr12:104650947:G:C | - | 0.104310793701983 | 0.0233038190159994 | LUSC | Female-baised eQTL |
| rs2695997 | chr12:104651475:A:G | - | 0.104280839249545 | 0.0238472337554929 | LUSC | Female-baised eQTL |
| rs2694409 | chr12:104651555:C:T | - | 0.104280839249545 | 0.0238472337554929 | LUSC | Female-baised eQTL |
| rs1863879 | chr12:104652472:G:A | - | 0.104280839249545 | 0.0238472337554929 | LUSC | Female-baised eQTL |
| rs2694415 | chr12:104646873:G:A | - | 0.0926159016840025 | 0.0382168562889554 | LUSC | Female-baised eQTL |
| rs61933077 | chr12:114590981:T:A | - | 0.291197531299147 | 0.00116454874795118 | BLCA | Female-baised eQTL |
| rs61933078 | chr12:114591749:T:C | - | 0.291197531299147 | 0.00116454874795118 | BLCA | Female-baised eQTL |
| rs61933079 | chr12:114592064:G:C | - | 0.291197531299147 | 0.00116454874795118 | BLCA | Female-baised eQTL |
| rs61933076 | chr12:114588962:G:A | - | 0.280875053308275 | 0.00135955593075524 | BLCA | Female-baised eQTL |
| rs116910653 | chr12:114585082:C:T | - | 0.257794466804857 | 0.0047655505197856 | BLCA | Female-baised eQTL |
| rs55902084 | chr12:114587075:T:C | - | 0.23315715537582 | 0.00623547461175701 | BLCA | Female-baised eQTL |
| rs73201543 | chr12:108347473:A:T | - | 0.268674440400215 | 0.0111602891039533 | BLCA | Female-baised eQTL |
| rs17040430 | chr12:108349043:G:T | - | 0.268674440400215 | 0.0111602891039533 | BLCA | Female-baised eQTL |
| rs56031065 | chr12:114562750:C:T | - | 0.228839776332498 | 0.0161397897098018 | BLCA | Female-baised eQTL |
| rs55941139 | chr12:114562897:G:A | - | 0.228839776332498 | 0.0161397897098018 | BLCA | Female-baised eQTL |
| rs61933072 | chr12:114563034:T:G | - | 0.228839776332498 | 0.0161397897098018 | BLCA | Female-baised eQTL |
| rs17678419 | chr12:114564141:T:G | - | 0.228839776332498 | 0.0161397897098018 | BLCA | Female-baised eQTL |
| rs78918482 | chr12:114570940:G:C | - | 0.228839776332498 | 0.0161397897098018 | BLCA | Female-baised eQTL |
| rs61931033 | chr12:114561335:A:T | - | 0.227096022642927 | 0.018030218537586 | BLCA | Female-baised eQTL |
| rs2569979 | chr12:105996143:G:A | - | 0.124717532805844 | 0.0280541771751022 | BLCA | Female-baised eQTL |
| rs11067175 | chr12:114575955:T:A | - | 0.191059875654616 | 0.0334633841731932 | BLCA | Female-baised eQTL |
| rs10861540 | chr12:106001024:C:T | - | 0.125090025882361 | 0.0355927585918074 | BLCA | Female-baised eQTL |
| rs2916099 | chr12:106012268:T:A | - | 0.122610326734913 | 0.0377964021775295 | BLCA | Female-baised eQTL |
| rs2569977 | chr12:105994601:A:G | - | 0.119519291885866 | 0.0425980191706423 | BLCA | Female-baised eQTL |
| rs2468215 | chr12:106008141:A:G | - | 0.119648329348123 | 0.0472702055371905 | BLCA | Female-baised eQTL |
| rs2436604 | chr12:105987222:C:T | - | 0.121859642326754 | 0.0490183642453648 | BLCA | Female-baised eQTL |
| rs12580397 | chr12:98538312:G:T | - | 0.111821002173027 | 0.0461614712408644 | COAD | Female-baised eQTL |
| rs36109055 | chr12:98540098:T:A | - | 0.111739479459886 | 0.046665571013572 | COAD | Female-baised eQTL |
| rs34303017 | chr12:98545598:A:G | - | 0.111739479459886 | 0.046665571013572 | COAD | Female-baised eQTL |
| rs34963912 | chr12:98550326:A:G | - | 0.111547165744954 | 0.0473491606836109 | COAD | Female-baised eQTL |
| rs61934009 | chr12:98550978:A:G | - | 0.111547165744954 | 0.0473491606836109 | COAD | Female-baised eQTL |
| rs71462240 | chr12:98552146:G:A | - | 0.111547165744954 | 0.0473491606836109 | COAD | Female-baised eQTL |
| rs12582779 | chr12:98571324:T:A | - | 0.111547165744954 | 0.0473491606836109 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs11109110 | chr12:97565796:A:T | - | 0.17035863272596 | 0.00961740294920076 | PCPG | Male-baised eQTL |
| rs12371659 | chr12:97579003:T:C | - | 0.157485474751829 | 0.0249925022839296 | PCPG | Male-baised eQTL |
| rs147748573 | chr12:97584852:G:A | - | 0.157485474751829 | 0.0249925022839296 | PCPG | Male-baised eQTL |
| rs11109117 | chr12:97586624:T:C | - | 0.157485474751829 | 0.0249925022839296 | PCPG | Male-baised eQTL |
| rs61941862 | chr12:97587090:A:G | - | 0.157485474751829 | 0.0249925022839296 | PCPG | Male-baised eQTL |
| rs55650004 | chr12:97587516:C:G | - | 0.157485474751829 | 0.0249925022839296 | PCPG | Male-baised eQTL |
| rs12372115 | chr12:97588923:G:T | - | 0.157485474751829 | 0.0249925022839296 | PCPG | Male-baised eQTL |
| rs11109120 | chr12:97591812:C:T | - | 0.157485474751829 | 0.0249925022839296 | PCPG | Male-baised eQTL |
| rs2701110 | chr12:114232065:C:A | - | 0.170610438440231 | 0.0324633774714801 | GBM | Male-baised eQTL |
| rs11066562 | chr12:109431580:G:A | - | 0.125837627356134 | 0.0104350871367944 | THCA | Male-baised eQTL |
| rs61941569 | chr12:109442892:A:C | - | 0.125823800316991 | 0.0106135740907859 | THCA | Male-baised eQTL |
| rs6606716 | chr12:109433907:T:C | - | 0.122310557775595 | 0.013465284477335 | THCA | Male-baised eQTL |
| rs61940343 | chr12:109436312:C:A | - | 0.121328714878135 | 0.0155629810041347 | THCA | Male-baised eQTL |
| rs7966238 | chr12:109423351:G:A | - | 0.106915829665092 | 0.0477451502112123 | THCA | Male-baised eQTL |
| rs57582846 | chr12:114937154:A:G | - | 0.0289025177408719 | 0.0459584530727574 | KIRC | Male-baised eQTL |
| rs2891538 | chr12:114936357:G:A | - | 0.028993612915331 | 0.0478511807849654 | KIRC | Male-baised eQTL |
| rs11066861 | chr12:113982465:G:A | - | 0.0997802493023204 | 0.00188953396890617 | LUAD | Male-baised eQTL |
| rs12423885 | chr12:101570029:C:T | - | 0.0898734854694599 | 0.0037455003605944 | LUAD | Male-baised eQTL |
| rs12424963 | chr12:101572645:C:T | - | 0.0898734854694599 | 0.0037455003605944 | LUAD | Male-baised eQTL |
| rs113931741 | chr12:101577563:T:C | - | 0.0587854372912702 | 0.0376860639207219 | LUAD | Male-baised eQTL |
| rs12580275 | chr12:101571075:G:A | - | 0.0575793217250485 | 0.0435080585640388 | LUAD | Male-baised eQTL |
| rs7314246 | chr12:101571383:G:T | - | 0.0575793217250485 | 0.0435080585640388 | LUAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000235162 |
| CpG Site: cg10623913 | |
| Position to Gene: gene | |
| Male Effect: -0.33919372426441 | |
| Female Effect: - | |
 | Gene ID: ENSG00000235162 |
| CpG Site: cg02062466 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.463646622583645 | |
 | Gene ID: ENSG00000235162 |
| CpG Site: cg10623913 | |
| Position to Gene: gene | |
| Male Effect: -0.30163101639876 | |
| Female Effect: - | |
 | Gene ID: ENSG00000235162 |
| CpG Site: cg26459229 | |
| Position to Gene: gene | |
| Male Effect: -0.463352974385003 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg10623913 | chr12:105333419 | gene | -0.33919372426441 | 7.69077747145011e-06 | -0.5292472659624833 | 2.1099100271170876e-08 | PAAD |
| cg10623913 | chr12:105333419 | gene | -0.30163101639876 | 1.35227134199376e-05 | -0.3574706935472808 | 4.947151764610719e-08 | STAD |
| cg26459229 | chr12:105350245 | gene | -0.463352974385003 | 1.51611044637817e-48 | -0.746228357754675 | 1.1957583819742193e-52 | LGG |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg02062466 | chr12:105318529 | gene | -0.463646622583645 | 5.1490366265482e-18 | -0.5530761463516878 | 7.830830684551097e-22 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of C12orf75 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
