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Gene: ENSG00000215193 |
Summary for PEX26 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000215193 | Gene symbol | PEX26 |
| Gene name | peroxisomal biogenesis factor 26 | |
| HGNC | 22965 | |
| Entrez ID | 55670 | |
| Gene type | protein_coding | |
| Synonyms | PEX26|FLJ20695 | |
| UniProtAcc | Q7Z412 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for PEX26 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for PEX26 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for PEX26 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUAD | cg05147578 | chr22:18076474 | CGI:chr22:18077792-18078644 | promoter | 5.85e-01 | 7.14e-01 | -3.84e+00 | 1.25e-04 | 3.40e-04 | -1.29e-01 |
| LUSC | cg05147578 | chr22:18076474 | CGI:chr22:18077792-18078644 | promoter | 5.34e-01 | 6.65e-01 | -2.44e+00 | 1.45e-02 | 1.85e-02 | -1.30e-01 |
| LUSC | cg02329029 | chr22:18076495 | CGI:chr22:18077792-18078644 | promoter | 8.24e-01 | 9.34e-01 | -3.58e+00 | 3.38e-04 | 1.31e-03 | -1.10e-01 |
| KIRP | cg05147578 | chr22:18076474 | CGI:chr22:18077792-18078644 | promoter | 6.23e-01 | 7.40e-01 | -2.91e+00 | 3.56e-03 | 5.35e-03 | -1.17e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LIHC | cg02329029 | chr22:18076495 | CGI:chr22:18077792-18078644 | promoter | 7.34e-01 | 4.97e-01 | 4.21e+00 | 2.56e-05 | 1.38e-04 | 2.36e-01 |
Top |
Exon skipping events with PSI in TCGA for PEX26 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| BLCA | exon_skip_363069 | 7.12e-01 | 8.12e-01 | -3.28e+00 | 1.03e-03 | 5.77e-03 | -1.00e-01 |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| COAD | exon_skip_363069 | 7.12e-01 | 8.16e-01 | -5.09e+00 | 3.52e-07 | 6.84e-06 | -1.04e-01 |
| READ | exon_skip_363069 | 6.83e-01 | 8.19e-01 | -3.82e+00 | 1.31e-04 | 3.84e-03 | -1.36e-01 |
Top |
RNA A-to-I editing events in TCGA for PEX26 |
| ∗Please access CAeditome for RNA editing annotation. |
| Landscape of RNA editing events across multiple cancer types. |
 |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| BRCA | PEX26-201 | chr22_18089964_+ | 3.12e-01 | 4.03e-01 | -2.00e+00 | 4.59e-02 | 4.97e-02 | -9.06e-02 |
| KIRC | PEX26-201 | chr22_18088682_+ | 1.42e-01 | 1.08e-01 | 2.14e+00 | 3.21e-02 | 4.77e-02 | 3.45e-02 |
| KIRC | PEX26-201 | chr22_18089963_+ | 2.67e-01 | 2.83e-01 | -2.05e+00 | 4.07e-02 | 4.92e-02 | -1.62e-02 |
| KIRC | PEX26-004 | chr22_18092724_+ | 2.23e-01 | 1.93e-01 | 2.76e+00 | 5.83e-03 | 4.08e-02 | 3.03e-02 |
| KIRC | PEX26-004 | chr22_18096006_+ | 2.73e-01 | 3.50e-01 | -2.07e+00 | 3.85e-02 | 4.91e-02 | -7.66e-02 |
| KIRC | PEX26-004 | chr22_18098428_+ | 2.66e-01 | 1.72e-01 | 2.89e+00 | 3.81e-03 | 4.08e-02 | 9.34e-02 |
| LUAD | PEX26-201 | chr22_18088602_+ | 2.01e-01 | 2.18e-01 | -2.00e+00 | 4.55e-02 | 4.83e-02 | -1.67e-02 |
| LUAD | PEX26-004 | chr22_18091518_+ | 3.54e-01 | 2.97e-01 | 2.04e+00 | 4.09e-02 | 4.68e-02 | 5.62e-02 |
| LUAD | PEX26-004 | chr22_18094476_+ | 3.31e-01 | 2.75e-01 | 2.14e+00 | 3.22e-02 | 4.37e-02 | 5.60e-02 |
| LUAD | PEX26-004 | chr22_18097958_+ | 3.39e-01 | 2.58e-01 | 2.05e+00 | 4.04e-02 | 4.66e-02 | 8.18e-02 |
| LGG | PEX26-201 | chr22_18088577_+ | 1.79e-01 | 1.65e-01 | 2.25e+00 | 2.43e-02 | 4.70e-02 | 1.41e-02 |
| LGG | PEX26-201 | chr22_18089831_+ | 3.50e-01 | 3.27e-01 | 2.02e+00 | 4.39e-02 | 4.92e-02 | 2.21e-02 |
| LGG | PEX26-201 | chr22_18089909_+ | 8.65e-01 | 8.45e-01 | 2.94e+00 | 3.27e-03 | 4.34e-02 | 2.00e-02 |
| LGG | PEX26-201 | chr22_18089964_+ | 2.77e-01 | 2.56e-01 | 2.68e+00 | 7.33e-03 | 4.34e-02 | 2.09e-02 |
| LGG | PEX26-004 | chr22_18098509_+ | 3.25e-01 | 3.80e-01 | -2.16e+00 | 3.11e-02 | 4.74e-02 | -5.54e-02 |
| THCA | PEX26-201 | chr22_18088511_+ | 1.60e-01 | 1.32e-01 | 2.16e+00 | 3.04e-02 | 4.91e-02 | 2.77e-02 |
| THCA | PEX26-201 | chr22_18088532_+ | 1.10e-01 | 1.36e-01 | -2.19e+00 | 2.85e-02 | 4.91e-02 | -2.55e-02 |
| THCA | PEX26-201 | chr22_18088577_+ | 2.25e-01 | 1.88e-01 | 3.30e+00 | 9.55e-04 | 4.76e-02 | 3.67e-02 |
| THCA | PEX26-004 | chr22_18092724_+ | 1.89e-01 | 2.38e-01 | -2.32e+00 | 2.05e-02 | 4.91e-02 | -4.90e-02 |
| THCA | PEX26-004 | chr22_18100132_+ | 2.83e-01 | 2.11e-01 | 2.19e+00 | 2.89e-02 | 4.91e-02 | 7.18e-02 |
| THCA | PEX26-004 | chr22_18100176_+ | 2.70e-01 | 3.55e-01 | -3.12e+00 | 1.82e-03 | 4.77e-02 | -8.57e-02 |
| HNSC | PEX26-201 | chr22_18088602_+ | 2.18e-01 | 2.64e-01 | -3.15e+00 | 1.61e-03 | 2.84e-02 | -4.55e-02 |
| HNSC | PEX26-201 | chr22_18088603_+ | 2.11e-01 | 2.36e-01 | -2.27e+00 | 2.30e-02 | 4.33e-02 | -2.45e-02 |
| HNSC | PEX26-201 | chr22_18089757_+ | 2.34e-01 | 3.00e-01 | -2.17e+00 | 3.02e-02 | 4.41e-02 | -6.62e-02 |
| HNSC | PEX26-201 | chr22_18089963_+ | 2.76e-01 | 2.93e-01 | -1.98e+00 | 4.73e-02 | 4.87e-02 | -1.72e-02 |
| LUSC | PEX26-201 | chr22_18089806_+ | 1.46e-01 | 1.82e-01 | -3.08e+00 | 2.07e-03 | 4.91e-02 | -3.61e-02 |
| LUSC | PEX26-201 | chr22_18089884_+ | 2.27e-01 | 2.15e-01 | 2.04e+00 | 4.11e-02 | 4.91e-02 | 1.21e-02 |
| LUSC | PEX26-004 | chr22_18091377_+ | 2.32e-01 | 2.63e-01 | -2.10e+00 | 3.54e-02 | 4.91e-02 | -3.04e-02 |
| LUSC | PEX26-004 | chr22_18100132_+ | 1.86e-01 | 2.56e-01 | -2.00e+00 | 4.55e-02 | 4.91e-02 | -6.97e-02 |
| SKCM | PEX26-201 | chr22_18088515_+ | 1.24e-01 | 1.38e-01 | -2.08e+00 | 3.78e-02 | 4.90e-02 | -1.42e-02 |
| SKCM | PEX26-201 | chr22_18088617_+ | 1.35e-01 | 1.90e-01 | -2.07e+00 | 3.88e-02 | 4.90e-02 | -5.44e-02 |
| COAD | PEX26-201 | chr22_18088579_+ | 1.67e-01 | 2.36e-01 | -3.15e+00 | 1.63e-03 | 1.45e-02 | -6.82e-02 |
| COAD | PEX26-201 | chr22_18088617_+ | 1.38e-01 | 2.29e-01 | -2.26e+00 | 2.40e-02 | 3.62e-02 | -9.06e-02 |
| COAD | PEX26-004 | chr22_18097082_+ | 3.31e-01 | 2.39e-01 | 2.12e+00 | 3.41e-02 | 4.20e-02 | 9.18e-02 |
| BLCA | PEX26-201 | chr22_18088711_+ | 1.84e-01 | 1.52e-01 | 2.10e+00 | 3.60e-02 | 4.98e-02 | 3.17e-02 |
| STAD | PEX26-201 | chr22_18088546_+ | 1.28e-01 | 1.74e-01 | -3.00e+00 | 2.67e-03 | 4.96e-02 | -4.60e-02 |
| STAD | PEX26-201 | chr22_18088579_+ | 2.25e-01 | 2.62e-01 | -2.47e+00 | 1.33e-02 | 4.96e-02 | -3.66e-02 |
| STAD | PEX26-201 | chr22_18088602_+ | 2.91e-01 | 3.27e-01 | -2.94e+00 | 3.26e-03 | 4.96e-02 | -3.61e-02 |
| STAD | PEX26-201 | chr22_18088711_+ | 1.84e-01 | 1.62e-01 | 2.03e+00 | 4.28e-02 | 4.96e-02 | 2.13e-02 |
| STAD | PEX26-201 | chr22_18089831_+ | 5.08e-01 | 5.46e-01 | -2.17e+00 | 3.00e-02 | 4.96e-02 | -3.81e-02 |
| STAD | PEX26-201 | chr22_18089843_+ | 1.31e-01 | 2.22e-01 | -1.98e+00 | 4.76e-02 | 4.96e-02 | -9.04e-02 |
| STAD | PEX26-201 | chr22_18089887_+ | 1.72e-01 | 1.90e-01 | -2.06e+00 | 3.94e-02 | 4.96e-02 | -1.81e-02 |
| STAD | PEX26-201 | chr22_18089945_+ | 1.12e-01 | 1.63e-01 | -2.19e+00 | 2.84e-02 | 4.96e-02 | -5.17e-02 |
| STAD | PEX26-004 | chr22_18091383_+ | 1.40e-01 | 1.72e-01 | -2.25e+00 | 2.44e-02 | 4.96e-02 | -3.14e-02 |
| STAD | PEX26-004 | chr22_18091544_+ | 1.43e-01 | 1.97e-01 | -2.10e+00 | 3.59e-02 | 4.96e-02 | -5.43e-02 |
| STAD | PEX26-004 | chr22_18096096_+ | 1.72e-01 | 2.37e-01 | -2.13e+00 | 3.36e-02 | 4.96e-02 | -6.54e-02 |
| STAD | PEX26-004 | chr22_18100255_+ | 2.90e-01 | 3.41e-01 | -2.17e+00 | 2.97e-02 | 4.96e-02 | -5.17e-02 |
| LIHC | PEX26-201 | chr22_18088505_+ | 2.08e-01 | 1.80e-01 | 2.16e+00 | 3.06e-02 | 4.57e-02 | 2.82e-02 |
| KIRP | PEX26-004 | chr22_18100258_+ | 5.64e-01 | 4.93e-01 | 2.02e+00 | 4.38e-02 | 4.86e-02 | 7.10e-02 |
| SARC | PEX26-201 | chr22_18088618_+ | 2.20e-01 | 1.48e-01 | 2.31e+00 | 2.08e-02 | 4.85e-02 | 7.19e-02 |
| SARC | PEX26-201 | chr22_18089909_+ | 8.17e-01 | 8.52e-01 | -2.29e+00 | 2.23e-02 | 4.85e-02 | -3.58e-02 |
| PCPG | PEX26-201 | chr22_18088603_+ | 2.35e-01 | 1.81e-01 | 3.60e+00 | 3.19e-04 | 4.98e-02 | 5.42e-02 |
| PCPG | PEX26-201 | chr22_18089909_+ | 8.38e-01 | 8.06e-01 | 2.47e+00 | 1.33e-02 | 4.98e-02 | 3.28e-02 |
| PAAD | PEX26-201 | chr22_18088603_+ | 2.02e-01 | 1.74e-01 | 1.97e+00 | 4.91e-02 | 4.96e-02 | 2.74e-02 |
| GBM | PEX26-201 | chr22_18088708_+ | 1.58e-01 | 1.91e-01 | -2.01e+00 | 4.45e-02 | 4.96e-02 | -3.30e-02 |
| GBM | PEX26-201 | chr22_18088711_+ | 1.32e-01 | 1.76e-01 | -2.17e+00 | 3.03e-02 | 4.96e-02 | -4.42e-02 |
| ESCA | PEX26-201 | chr22_18088708_+ | 1.77e-01 | 2.16e-01 | -2.17e+00 | 2.99e-02 | 4.99e-02 | -3.86e-02 |
| ESCA | PEX26-004 | chr22_18097082_+ | 3.88e-01 | 2.85e-01 | 2.45e+00 | 1.41e-02 | 4.99e-02 | 1.03e-01 |
| ESCA | PEX26-004 | chr22_18098443_+ | 3.38e-01 | 2.70e-01 | 2.13e+00 | 3.28e-02 | 4.99e-02 | 6.83e-02 |
| ESCA | PEX26-004 | chr22_18098509_+ | 3.17e-01 | 2.42e-01 | 2.32e+00 | 2.04e-02 | 4.99e-02 | 7.52e-02 |
| ESCA | PEX26-004 | chr22_18098553_+ | 3.23e-01 | 2.37e-01 | 2.50e+00 | 1.24e-02 | 4.99e-02 | 8.59e-02 |
| ESCA | PEX26-004 | chr22_18100132_+ | 2.44e-01 | 2.98e-01 | -2.08e+00 | 3.77e-02 | 4.99e-02 | -5.43e-02 |
| ESCA | PEX26-004 | chr22_18100295_+ | 2.32e-01 | 3.16e-01 | -2.36e+00 | 1.81e-02 | 4.99e-02 | -8.33e-02 |
| LAML | PEX26-201 | chr22_18089963_+ | 1.71e-01 | 2.06e-01 | -2.14e+00 | 3.27e-02 | 4.94e-02 | -3.55e-02 |
| LAML | PEX26-201 | chr22_18089964_+ | 1.90e-01 | 2.34e-01 | -2.06e+00 | 3.98e-02 | 4.95e-02 | -4.35e-02 |
| THYM | PEX26-201 | chr22_18089887_+ | 1.26e-01 | 1.72e-01 | -2.34e+00 | 1.91e-02 | 4.73e-02 | -4.55e-02 |
| THYM | PEX26-004 | chr22_18091629_+ | 2.56e-01 | 1.73e-01 | 2.56e+00 | 1.06e-02 | 4.73e-02 | 8.31e-02 |
| THYM | PEX26-004 | chr22_18100179_+ | 3.36e-01 | 2.30e-01 | 2.58e+00 | 9.78e-03 | 4.73e-02 | 1.06e-01 |
| MESO | PEX26-201 | chr22_18089964_+ | 3.94e-01 | 2.99e-01 | 2.22e+00 | 2.62e-02 | 4.83e-02 | 9.51e-02 |
| ACC | PEX26-201 | chr22_18089884_+ | 2.52e-01 | 2.09e-01 | 2.21e+00 | 2.68e-02 | 4.94e-02 | 4.30e-02 |
| ACC | PEX26-201 | chr22_18089964_+ | 3.64e-01 | 2.87e-01 | 2.41e+00 | 1.60e-02 | 4.94e-02 | 7.76e-02 |
| CHOL | PEX26-004 | chr22_18097082_+ | 5.97e-01 | 3.35e-01 | 2.69e+00 | 7.08e-03 | 4.94e-02 | 2.62e-01 |
| CHOL | PEX26-004 | chr22_18100098_+ | 2.10e-01 | 3.29e-01 | -2.82e+00 | 4.80e-03 | 4.94e-02 | -1.19e-01 |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| KIRC | PEX26-201 | chr22_18088505_+ | 1.51e-01 | 1.17e-01 | 2.77e+00 | 5.61e-03 | 1.23e-02 | 3.41e-02 |
| KIRC | PEX26-201 | chr22_18088572_+ | 2.26e-01 | 1.88e-01 | 2.43e+00 | 1.53e-02 | 2.37e-02 | 3.81e-02 |
| KIRC | PEX26-201 | chr22_18088593_+ | 1.54e-01 | 1.16e-01 | 2.17e+00 | 3.02e-02 | 3.66e-02 | 3.83e-02 |
| KIRC | PEX26-201 | chr22_18088602_+ | 2.04e-01 | 1.71e-01 | 2.57e+00 | 1.01e-02 | 1.82e-02 | 3.27e-02 |
| KIRC | PEX26-201 | chr22_18088603_+ | 2.10e-01 | 1.80e-01 | 2.00e+00 | 4.51e-02 | 4.68e-02 | 2.94e-02 |
| KIRC | PEX26-201 | chr22_18088708_+ | 1.58e-01 | 1.22e-01 | 2.68e+00 | 7.43e-03 | 1.47e-02 | 3.63e-02 |
| KIRC | PEX26-201 | chr22_18089757_+ | 2.47e-01 | 1.98e-01 | 2.48e+00 | 1.32e-02 | 2.15e-02 | 4.85e-02 |
| KIRC | PEX26-201 | chr22_18089806_+ | 1.80e-01 | 1.43e-01 | 3.39e+00 | 7.01e-04 | 2.93e-03 | 3.71e-02 |
| KIRC | PEX26-004 | chr22_18091446_+ | 3.06e-01 | 2.30e-01 | 2.23e+00 | 2.54e-02 | 3.30e-02 | 7.59e-02 |
| LUAD | PEX26-201 | chr22_18088665_+ | 3.46e-01 | 2.84e-01 | 2.16e+00 | 3.04e-02 | 3.74e-02 | 6.20e-02 |
| LUAD | PEX26-201 | chr22_18089963_+ | 3.03e-01 | 2.36e-01 | 2.30e+00 | 2.16e-02 | 3.00e-02 | 6.68e-02 |
| THCA | PEX26-201 | chr22_18089831_+ | 3.37e-01 | 2.63e-01 | 2.18e+00 | 2.95e-02 | 3.62e-02 | 7.45e-02 |
| HNSC | PEX26-201 | chr22_18088577_+ | 1.99e-01 | 1.31e-01 | 2.13e+00 | 3.35e-02 | 3.62e-02 | 6.85e-02 |
| COAD | PEX26-004 | chr22_18091531_+ | 2.89e-01 | 1.91e-01 | 2.61e+00 | 9.02e-03 | 1.63e-02 | 9.84e-02 |
| STAD | PEX26-201 | chr22_18088665_+ | 3.71e-01 | 3.11e-01 | 2.36e+00 | 1.85e-02 | 3.18e-02 | 6.05e-02 |
| STAD | PEX26-201 | chr22_18088708_+ | 1.95e-01 | 1.52e-01 | 2.12e+00 | 3.39e-02 | 4.18e-02 | 4.31e-02 |
| STAD | PEX26-201 | chr22_18088711_+ | 1.84e-01 | 1.28e-01 | 2.12e+00 | 3.41e-02 | 4.19e-02 | 5.53e-02 |
| STAD | PEX26-004 | chr22_18091518_+ | 4.40e-01 | 3.35e-01 | 2.21e+00 | 2.71e-02 | 3.76e-02 | 1.06e-01 |
| STAD | PEX26-004 | chr22_18096003_+ | 2.48e-01 | 3.96e-01 | -2.02e+00 | 4.29e-02 | 4.67e-02 | -1.48e-01 |
| STAD | PEX26-004 | chr22_18098452_+ | 2.28e-01 | 3.14e-01 | -2.66e+00 | 7.83e-03 | 2.11e-02 | -8.62e-02 |
| KIRP | PEX26-201 | chr22_18088505_+ | 1.54e-01 | 1.21e-01 | 2.28e+00 | 2.26e-02 | 3.45e-02 | 3.22e-02 |
| KIRP | PEX26-201 | chr22_18088579_+ | 1.63e-01 | 1.28e-01 | 2.29e+00 | 2.19e-02 | 3.39e-02 | 3.52e-02 |
| KIRP | PEX26-201 | chr22_18089964_+ | 3.02e-01 | 3.45e-01 | -2.31e+00 | 2.07e-02 | 3.28e-02 | -4.37e-02 |
| ESCA | PEX26-201 | chr22_18088602_+ | 2.77e-01 | 1.77e-01 | 2.71e+00 | 6.75e-03 | 1.70e-02 | 1.00e-01 |
| ESCA | PEX26-201 | chr22_18088655_+ | 3.96e-01 | 2.24e-01 | 3.46e+00 | 5.44e-04 | 5.76e-03 | 1.72e-01 |
| ESCA | PEX26-201 | chr22_18089884_+ | 3.46e-01 | 2.47e-01 | 2.28e+00 | 2.27e-02 | 3.30e-02 | 9.91e-02 |
| ESCA | PEX26-201 | chr22_18089964_+ | 4.24e-01 | 2.71e-01 | 3.40e+00 | 6.82e-04 | 6.21e-03 | 1.53e-01 |
| KICH | PEX26-201 | chr22_18088572_+ | 1.54e-01 | 1.87e-01 | -2.69e+00 | 7.24e-03 | 1.51e-02 | -3.33e-02 |
| KICH | PEX26-201 | chr22_18088602_+ | 1.22e-01 | 1.46e-01 | -2.00e+00 | 4.51e-02 | 4.69e-02 | -2.46e-02 |
| KICH | PEX26-201 | chr22_18088665_+ | 2.15e-01 | 2.80e-01 | -2.61e+00 | 9.13e-03 | 1.76e-02 | -6.50e-02 |
| KICH | PEX26-201 | chr22_18089831_+ | 2.36e-01 | 3.39e-01 | -3.23e+00 | 1.26e-03 | 5.27e-03 | -1.03e-01 |
| KICH | PEX26-201 | chr22_18089884_+ | 1.26e-01 | 1.71e-01 | -3.13e+00 | 1.76e-03 | 6.32e-03 | -4.47e-02 |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| BRCA | PEX26-201 | chr22_18088505_+ | 1.57e-01 | 1.19e-01 | 3.47e+00 | 5.23e-04 | 1.10e-03 | 3.85e-02 |
| BRCA | PEX26-201 | chr22_18088572_+ | 2.41e-01 | 1.92e-01 | 4.16e+00 | 3.15e-05 | 8.79e-05 | 4.94e-02 |
| BRCA | PEX26-201 | chr22_18088577_+ | 2.28e-01 | 1.65e-01 | 5.35e+00 | 8.85e-08 | 4.01e-07 | 6.27e-02 |
| BRCA | PEX26-201 | chr22_18088579_+ | 2.07e-01 | 1.46e-01 | 3.96e+00 | 7.58e-05 | 1.95e-04 | 6.08e-02 |
| BRCA | PEX26-201 | chr22_18088601_+ | 1.60e-01 | 1.09e-01 | 2.97e+00 | 2.96e-03 | 4.99e-03 | 5.11e-02 |
| BRCA | PEX26-201 | chr22_18088602_+ | 2.21e-01 | 1.54e-01 | 5.38e+00 | 7.25e-08 | 3.33e-07 | 6.73e-02 |
| BRCA | PEX26-201 | chr22_18088603_+ | 2.15e-01 | 1.73e-01 | 4.05e+00 | 5.23e-05 | 1.39e-04 | 4.15e-02 |
| BRCA | PEX26-201 | chr22_18088655_+ | 3.87e-01 | 2.66e-01 | 9.13e+00 | 7.12e-20 | 1.74e-18 | 1.21e-01 |
| BRCA | PEX26-201 | chr22_18088665_+ | 4.00e-01 | 2.79e-01 | 1.00e+01 | 1.52e-23 | 6.24e-22 | 1.21e-01 |
| BRCA | PEX26-201 | chr22_18088708_+ | 1.84e-01 | 1.30e-01 | 4.21e+00 | 2.59e-05 | 7.36e-05 | 5.39e-02 |
| BRCA | PEX26-201 | chr22_18088711_+ | 1.84e-01 | 1.36e-01 | 2.74e+00 | 6.14e-03 | 9.29e-03 | 4.78e-02 |
| BRCA | PEX26-201 | chr22_18089757_+ | 3.03e-01 | 2.42e-01 | 2.63e+00 | 8.41e-03 | 1.21e-02 | 6.09e-02 |
| BRCA | PEX26-201 | chr22_18089806_+ | 2.01e-01 | 1.43e-01 | 4.16e+00 | 3.17e-05 | 8.83e-05 | 5.77e-02 |
| BRCA | PEX26-201 | chr22_18089831_+ | 4.03e-01 | 2.60e-01 | 8.66e+00 | 4.58e-18 | 8.84e-17 | 1.43e-01 |
| BRCA | PEX26-201 | chr22_18089884_+ | 2.84e-01 | 1.66e-01 | 8.98e+00 | 2.77e-19 | 6.24e-18 | 1.18e-01 |
| BRCA | PEX26-201 | chr22_18089909_+ | 8.41e-01 | 7.28e-01 | 1.03e+01 | 5.28e-25 | 2.70e-23 | 1.13e-01 |
| BRCA | PEX26-201 | chr22_18089963_+ | 3.24e-01 | 1.87e-01 | 9.92e+00 | 3.38e-23 | 1.33e-21 | 1.37e-01 |
| BRCA | PEX26-201 | chr22_18089964_+ | 4.03e-01 | 2.42e-01 | 1.24e+01 | 3.19e-35 | 1.08e-32 | 1.60e-01 |
| BRCA | PEX26-201 | chr22_18089976_+ | 1.59e-01 | 1.30e-01 | 3.57e+00 | 3.62e-04 | 7.91e-04 | 2.89e-02 |
| LUAD | PEX26-201 | chr22_18089884_+ | 2.67e-01 | 1.92e-01 | 3.21e+00 | 1.33e-03 | 4.70e-03 | 7.49e-02 |
| THCA | PEX26-201 | chr22_18088572_+ | 1.88e-01 | 1.52e-01 | 2.37e+00 | 1.80e-02 | 2.51e-02 | 3.65e-02 |
| THCA | PEX26-201 | chr22_18088577_+ | 1.88e-01 | 1.52e-01 | 2.17e+00 | 3.00e-02 | 3.58e-02 | 3.66e-02 |
| THCA | PEX26-201 | chr22_18088602_+ | 1.96e-01 | 1.64e-01 | 2.10e+00 | 3.54e-02 | 4.00e-02 | 3.15e-02 |
| THCA | PEX26-201 | chr22_18088603_+ | 2.02e-01 | 1.77e-01 | 1.97e+00 | 4.92e-02 | 4.94e-02 | 2.57e-02 |
| THCA | PEX26-201 | chr22_18088708_+ | 1.50e-01 | 1.15e-01 | 2.17e+00 | 3.03e-02 | 3.60e-02 | 3.51e-02 |
| HNSC | PEX26-201 | chr22_18088602_+ | 2.64e-01 | 1.84e-01 | 2.10e+00 | 3.61e-02 | 4.02e-02 | 8.01e-02 |
| HNSC | PEX26-201 | chr22_18088603_+ | 2.36e-01 | 1.80e-01 | 2.21e+00 | 2.74e-02 | 3.29e-02 | 5.61e-02 |
| COAD | PEX26-004 | chr22_18091378_+ | 2.65e-01 | 1.78e-01 | 2.21e+00 | 2.72e-02 | 3.54e-02 | 8.73e-02 |
| COAD | PEX26-004 | chr22_18091517_+ | 2.95e-01 | 1.50e-01 | 2.54e+00 | 1.12e-02 | 2.10e-02 | 1.45e-01 |
| COAD | PEX26-004 | chr22_18091518_+ | 3.55e-01 | 1.65e-01 | 3.73e+00 | 1.95e-04 | 2.21e-03 | 1.90e-01 |
| COAD | PEX26-004 | chr22_18097082_+ | 2.39e-01 | 1.45e-01 | 3.13e+00 | 1.73e-03 | 8.25e-03 | 9.44e-02 |
| COAD | PEX26-004 | chr22_18100258_+ | 5.71e-01 | 4.32e-01 | 2.37e+00 | 1.79e-02 | 2.78e-02 | 1.39e-01 |
| BLCA | PEX26-201 | chr22_18089964_+ | 3.49e-01 | 2.18e-01 | 2.62e+00 | 8.68e-03 | 3.32e-02 | 1.31e-01 |
| STAD | PEX26-201 | chr22_18088602_+ | 3.27e-01 | 2.16e-01 | 2.35e+00 | 1.90e-02 | 3.30e-02 | 1.11e-01 |
| LIHC | PEX26-201 | chr22_18088603_+ | 2.23e-01 | 2.88e-01 | -2.02e+00 | 4.32e-02 | 4.79e-02 | -6.49e-02 |
| LIHC | PEX26-201 | chr22_18089909_+ | 7.89e-01 | 7.14e-01 | 2.81e+00 | 5.03e-03 | 2.36e-02 | 7.53e-02 |
| KIRP | PEX26-004 | chr22_18091517_+ | 3.08e-01 | 2.39e-01 | 2.61e+00 | 9.17e-03 | 2.56e-02 | 6.95e-02 |
| READ | PEX26-201 | chr22_18088572_+ | 1.97e-01 | 1.22e-01 | 2.13e+00 | 3.32e-02 | 4.66e-02 | 7.48e-02 |
| READ | PEX26-201 | chr22_18088602_+ | 2.50e-01 | 1.41e-01 | 2.38e+00 | 1.75e-02 | 4.09e-02 | 1.09e-01 |
| READ | PEX26-201 | chr22_18088655_+ | 3.20e-01 | 2.15e-01 | 2.01e+00 | 4.47e-02 | 4.90e-02 | 1.05e-01 |
| READ | PEX26-201 | chr22_18089909_+ | 7.35e-01 | 6.08e-01 | 2.80e+00 | 5.14e-03 | 3.59e-02 | 1.27e-01 |
| KICH | PEX26-201 | chr22_18088603_+ | 1.36e-01 | 1.92e-01 | -2.22e+00 | 2.62e-02 | 3.30e-02 | -5.55e-02 |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for PEX26 |
| TFs related to PEX26. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| ACC | ELK4 | PEX26 | 3.98e+00 | 9.82e-01 | 3.09e+00 | 6.28e-03 | Male-biased |
| ACC | GABPA | PEX26 | 4.03e+00 | 9.87e-01 | 2.90e+00 | 2.42e-03 | Male-biased |
| ACC | NR1H4 | PEX26 | 3.98e+00 | 9.81e-01 | 3.11e+00 | 7.15e-03 | Male-biased |
| ACC | PRDM6 | PEX26 | 2.75e+00 | 2.04e-03 | 3.95e+00 | 9.85e-01 | Female-biased |
| ACC | TEAD1 | PEX26 | 3.62e+00 | 9.36e-03 | 4.47e+00 | 9.85e-01 | Female-biased |
| ACC | ZFP64 | PEX26 | 4.09e+00 | 9.82e-01 | 3.24e+00 | 7.76e-03 | Male-biased |
| ACC | ZNF2 | PEX26 | 4.19e+00 | 9.87e-01 | 3.22e+00 | 4.69e-03 | Male-biased |
| ACC | ZNF200 | PEX26 | 4.34e+00 | 9.87e-01 | 3.42e+00 | 5.99e-03 | Male-biased |
| ACC | ZNF235 | PEX26 | 2.81e+00 | 2.57e-03 | 3.97e+00 | 9.85e-01 | Female-biased |
| ACC | ZNF320 | PEX26 | 4.13e+00 | 9.83e-01 | 3.29e+00 | 8.05e-03 | Male-biased |
| ACC | ZNF441 | PEX26 | 4.11e+00 | 9.83e-01 | 3.26e+00 | 7.77e-03 | Male-biased |
| ACC | ZNF487 | PEX26 | 3.13e+00 | 4.84e-03 | 4.13e+00 | 9.86e-01 | Female-biased |
| ACC | ZNF620 | PEX26 | 3.75e+00 | 7.51e-03 | 4.66e+00 | 9.88e-01 | Female-biased |
| ACC | ZNF792 | PEX26 | 4.21e+00 | 9.85e-01 | 3.31e+00 | 6.50e-03 | Male-biased |
| ACC | ZSCAN30 | PEX26 | 4.16e+00 | 9.85e-01 | 3.24e+00 | 6.02e-03 | Male-biased |
| CHOL | ZNF121 | PEX26 | 4.67e+00 | 9.91e-01 | 3.53e+00 | 5.22e-03 | Male-biased |
| CHOL | ZNF181 | PEX26 | 4.53e+00 | 9.89e-01 | 3.43e+00 | 5.94e-03 | Male-biased |
| CHOL | ZNF33A | PEX26 | 4.56e+00 | 9.88e-01 | 3.51e+00 | 7.64e-03 | Male-biased |
| CHOL | ZNF571 | PEX26 | 4.59e+00 | 9.81e-01 | 3.72e+00 | 1.48e-02 | Male-biased |
| ESCA | DNMT1 | PEX26 | 4.01e+00 | 9.87e-01 | 2.81e+00 | 5.99e-04 | Male-biased |
| ESCA | MBD2 | PEX26 | 4.09e+00 | 9.87e-01 | 3.11e+00 | 2.19e-03 | Male-biased |
| ESCA | ZFP64 | PEX26 | 4.01e+00 | 9.85e-01 | 3.08e+00 | 2.97e-03 | Male-biased |
| ESCA | ZNF2 | PEX26 | 4.10e+00 | 9.84e-01 | 3.28e+00 | 5.37e-03 | Male-biased |
| ESCA | ZNF267 | PEX26 | 4.11e+00 | 9.83e-01 | 3.33e+00 | 6.81e-03 | Male-biased |
| ESCA | ZNF311 | PEX26 | 4.16e+00 | 9.89e-01 | 3.14e+00 | 1.73e-03 | Male-biased |
| ESCA | ZNF44 | PEX26 | 4.13e+00 | 9.89e-01 | 3.07e+00 | 1.43e-03 | Male-biased |
| LAML | MBD2 | PEX26 | 4.19e+00 | 9.81e-01 | 3.06e+00 | 4.39e-03 | Male-biased |
| LAML | PRDM6 | PEX26 | 2.65e+00 | 1.44e-03 | 4.03e+00 | 9.81e-01 | Female-biased |
| LAML | ZNF101 | PEX26 | 4.37e+00 | 9.80e-01 | 3.44e+00 | 9.12e-03 | Male-biased |
| LAML | ZNF121 | PEX26 | 3.62e+00 | 7.74e-03 | 4.58e+00 | 9.85e-01 | Female-biased |
| LAML | ZNF2 | PEX26 | 4.31e+00 | 9.81e-01 | 3.30e+00 | 6.70e-03 | Male-biased |
| LAML | ZNF235 | PEX26 | 2.67e+00 | 3.39e-04 | 4.39e+00 | 9.90e-01 | Female-biased |
| LAML | ZNF487 | PEX26 | 3.03e+00 | 1.15e-03 | 4.47e+00 | 9.90e-01 | Female-biased |
| MESO | DNMT1 | PEX26 | 3.88e+00 | 9.81e-01 | 2.04e+00 | 1.05e-03 | Male-biased |
| MESO | MBD2 | PEX26 | 4.21e+00 | 9.86e-01 | 2.74e+00 | 4.00e-03 | Male-biased |
| MESO | ZNF2 | PEX26 | 4.26e+00 | 9.83e-01 | 2.98e+00 | 7.62e-03 | Male-biased |
| MESO | ZNF311 | PEX26 | 4.16e+00 | 9.85e-01 | 2.66e+00 | 3.66e-03 | Male-biased |
| PCPG | PRDM6 | PEX26 | 3.10e+00 | 3.03e-03 | 4.17e+00 | 9.86e-01 | Female-biased |
| PCPG | ZNF121 | PEX26 | 2.85e+00 | 1.79e-03 | 4.03e+00 | 9.85e-01 | Female-biased |
| PCPG | ZNF181 | PEX26 | 2.78e+00 | 1.97e-03 | 3.93e+00 | 9.83e-01 | Female-biased |
| PCPG | ZNF235 | PEX26 | 3.11e+00 | 2.13e-03 | 4.26e+00 | 9.89e-01 | Female-biased |
| PCPG | ZNF33A | PEX26 | 2.79e+00 | 2.27e-03 | 3.91e+00 | 9.82e-01 | Female-biased |
| PCPG | ZNF487 | PEX26 | 3.23e+00 | 2.24e-03 | 4.36e+00 | 9.90e-01 | Female-biased |
| PCPG | ZNF571 | PEX26 | 3.12e+00 | 3.48e-03 | 4.16e+00 | 9.86e-01 | Female-biased |
| READ | ELK4 | PEX26 | 4.49e+00 | 9.85e-01 | 3.58e+00 | 6.63e-03 | Male-biased |
| READ | ERF | PEX26 | 4.94e+00 | 9.84e-01 | 4.17e+00 | 1.20e-02 | Male-biased |
| READ | GABPA | PEX26 | 4.36e+00 | 9.84e-01 | 3.43e+00 | 6.18e-03 | Male-biased |
| READ | MBD2 | PEX26 | 3.06e+00 | 3.53e-03 | 4.16e+00 | 9.83e-01 | Female-biased |
| READ | NR1H4 | PEX26 | 2.56e+00 | 5.69e-04 | 4.18e+00 | 9.87e-01 | Female-biased |
| READ | PLAG1 | PEX26 | 2.50e+00 | 5.07e-04 | 4.15e+00 | 9.86e-01 | Female-biased |
| READ | RBAK | PEX26 | 2.59e+00 | 6.07e-04 | 4.19e+00 | 9.87e-01 | Female-biased |
| READ | ZFP14 | PEX26 | 2.74e+00 | 7.06e-04 | 4.29e+00 | 9.89e-01 | Female-biased |
| READ | ZFP64 | PEX26 | 2.94e+00 | 2.36e-03 | 4.14e+00 | 9.84e-01 | Female-biased |
| READ | ZNF101 | PEX26 | 2.95e+00 | 6.78e-04 | 4.52e+00 | 9.92e-01 | Female-biased |
| READ | ZNF2 | PEX26 | 3.20e+00 | 4.01e-03 | 4.26e+00 | 9.85e-01 | Female-biased |
| READ | ZNF200 | PEX26 | 4.70e+00 | 9.88e-01 | 3.77e+00 | 6.27e-03 | Male-biased |
| READ | ZNF212 | PEX26 | 3.07e+00 | 4.34e-03 | 4.10e+00 | 9.81e-01 | Female-biased |
| READ | ZNF235 | PEX26 | 4.27e+00 | 9.85e-01 | 3.15e+00 | 3.02e-03 | Male-biased |
| READ | ZNF311 | PEX26 | 3.15e+00 | 4.14e-03 | 4.20e+00 | 9.84e-01 | Female-biased |
| READ | ZNF320 | PEX26 | 2.74e+00 | 7.75e-04 | 4.27e+00 | 9.88e-01 | Female-biased |
| READ | ZNF324B | PEX26 | 3.34e+00 | 4.78e-03 | 4.36e+00 | 9.86e-01 | Female-biased |
| READ | ZNF394 | PEX26 | 2.83e+00 | 9.06e-04 | 4.31e+00 | 9.89e-01 | Female-biased |
| READ | ZNF436 | PEX26 | 2.56e+00 | 7.31e-04 | 4.10e+00 | 9.85e-01 | Female-biased |
| READ | ZNF44 | PEX26 | 3.12e+00 | 3.13e-03 | 4.25e+00 | 9.86e-01 | Female-biased |
| READ | ZNF479 | PEX26 | 2.98e+00 | 1.24e-03 | 4.37e+00 | 9.90e-01 | Female-biased |
| READ | ZNF555 | PEX26 | 3.04e+00 | 1.70e-03 | 4.34e+00 | 9.89e-01 | Female-biased |
| READ | ZNF596 | PEX26 | 2.91e+00 | 1.30e-03 | 4.28e+00 | 9.88e-01 | Female-biased |
| READ | ZNF682 | PEX26 | 3.01e+00 | 2.19e-03 | 4.24e+00 | 9.86e-01 | Female-biased |
| READ | ZNF701 | PEX26 | 3.12e+00 | 1.99e-03 | 4.38e+00 | 9.89e-01 | Female-biased |
| READ | ZNF708 | PEX26 | 3.20e+00 | 2.95e-03 | 4.35e+00 | 9.88e-01 | Female-biased |
| READ | ZSCAN30 | PEX26 | 2.87e+00 | 1.58e-03 | 4.19e+00 | 9.86e-01 | Female-biased |
| PEX26 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for PEX26 |
| RBPs related to ES in PEX26. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| KICH | PPRC1 | exon_skip_363055 | 1.04e+01 | 2.66e-03 | 1.08e+01 | 9.96e-01 | Female-biased |
| KICH | RBM8A | exon_skip_363055 | 1.05e+01 | 1.27e-02 | 1.08e+01 | 9.86e-01 | Female-biased |
| PEX26 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs112257461 | chr22:22132553:A:G | - | 0.223591895501182 | 0.023350949141648 | LIHC | Female-baised eQTL |
| rs73151960 | chr22:22138378:G:T | - | 0.222902700103422 | 0.0244909962651067 | LIHC | Female-baised eQTL |
| rs17557090 | chr22:22140471:C:T | - | 0.222902700103422 | 0.0244909962651067 | LIHC | Female-baised eQTL |
| rs17472471 | chr22:22143268:A:G | - | 0.222886498615675 | 0.0245190130530588 | LIHC | Female-baised eQTL |
| rs16984673 | chr22:22153957:C:T | - | 0.211740720522674 | 0.0353918536585182 | LIHC | Female-baised eQTL |
| rs16984675 | chr22:22154039:G:T | - | 0.211740720522674 | 0.0353918536585182 | LIHC | Female-baised eQTL |
| rs2073744 | chr22:19972432:A:G | - | -0.120589471936216 | 0.00329844898458691 | LGG | Female-baised eQTL |
| rs2518823 | chr22:19972665:T:C | - | -0.118013063213667 | 0.00459775234853276 | LGG | Female-baised eQTL |
| rs165840 | chr22:19970264:C:T | - | -0.111800203385094 | 0.0114858595215904 | LGG | Female-baised eQTL |
| rs165824 | chr22:19971843:G:A | - | -0.111800203385094 | 0.0114858595215904 | LGG | Female-baised eQTL |
| rs5751681 | chr22:23477779:G:A | - | 0.102431741318012 | 0.025708721465568 | LGG | Female-baised eQTL |
| rs2330503 | chr22:23477646:T:C | - | 0.0958686046782059 | 0.0482274438869735 | LGG | Female-baised eQTL |
| rs150661445 | chr22:23478024:G:A | - | 0.0958686046782059 | 0.0482274438869735 | LGG | Female-baised eQTL |
| rs555454 | chr22:20629746:A:T | - | -0.0733450150270519 | 0.0225781458172803 | LUAD | Female-baised eQTL |
| rs5748769 | chr22:16968225:G:C | - | 0.103134464319824 | 0.0315786164034297 | LUAD | Female-baised eQTL |
| rs9604803 | chr22:17915441:C:A | - | 0.0612781918425479 | 0.0106865868555621 | COAD | Female-baised eQTL |
| rs73151057 | chr22:17915147:T:G | - | 0.0533030649924408 | 0.042815696365508 | COAD | Female-baised eQTL |
| rs5746493 | chr22:17914806:C:T | - | 0.0541768436368746 | 0.0438684343547276 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs56222076 | chr22:19213848:G:A | - | 0.0401958517286976 | 0.019800415621195 | HNSC | Male-baised eQTL |
| rs5997054 | chr22:20402693:T:C | - | 0.0422418393735431 | 0.0317967908097519 | HNSC | Male-baised eQTL |
| rs6004975 | chr22:20402965:C:G | - | 0.0452091924052484 | 0.0326774529222108 | HNSC | Male-baised eQTL |
| rs4819857 | chr22:20034464:A:G | - | 0.0294171446492393 | 0.0437594534084093 | BLCA | Male-baised eQTL |
| rs713900 | chr22:26502276:A:G | - | -0.10976820401181 | 0.00934021190603548 | LUAD | Male-baised eQTL |
| rs134144 | chr22:26513004:G:A | - | 0.116258822528942 | 0.0121573240706363 | LUAD | Male-baised eQTL |
| rs5761565 | chr22:26498297:T:C | - | -0.0919711552559388 | 0.0328655720824541 | LUAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000215193 |
| CpG Site: cg04800681 | |
| Position to Gene: gene | |
| Male Effect: -0.377872811250111 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg04800681 | chr22:18111469 | gene | -0.377872811250111 | 8.61973223761556e-09 | -0.43269138418499276 | 1.370572776939951e-11 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_363069 | chr22:18085111:18085258 | In-frame | rs9605258 | chr22:17318478:T:G | Distant upstream | -0.0409304104008765 | 0.0344059934510123 | LUSC | Female-baised sQTL |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_363069 | chr22:18085111:18085258 | In-frame | rs4819645 | chr22:17889943:A:G | Distant upstream | -0.0315937492918654 | 0.0420679941696605 | HNSC | Male-baised sQTL |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of PEX26 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000215193 | PEX26 | C0043459 | Zellweger Syndrome | 2 | CTD_human |
| ENSG00000215193 | PEX26 | C0162309 | Adrenoleukodystrophy | 1 | CTD_human |
| ENSG00000215193 | PEX26 | C0282527 | Infantile Refsum Disease (disorder) | 1 | CTD_human |
| ENSG00000215193 | PEX26 | C0751594 | Zellweger-Like Syndrome | 2 | CTD_human |
| ENSG00000215193 | PEX26 | C1527231 | Adrenomyeloneuropathy | 1 | CTD_human |
| ENSG00000215193 | PEX26 | C1832200 | Peroxisome biogenesis disorders | 1 | CTD_human |
| ENSG00000215193 | PEX26 | C3553951 | PEROXISOME BIOGENESIS DISORDER 7B | 1 | CTD_human |
| ENSG00000215193 | PEX26 | C3658299 | Zellweger Spectrum | 2 | CTD_human |
| ENSG00000215193 | PEX26 | C3888385 | PEROXISOME BIOGENESIS DISORDER 7A (ZELLWEGER) | 1 | CTD_human |
