|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
|
Gene: ENSG00000214510 |
Summary for SPINK13 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000214510 | Gene symbol | SPINK13 |
| Gene name | serine peptidase inhibitor Kazal type 13 | |
| HGNC | 27200 | |
| Entrez ID | 153218 | |
| Gene type | protein_coding | |
| Synonyms | SPINK13|SPINK5L3|LiESP6|HESPINTOR|MGC149260 | |
| UniProtAcc | Q1W4C9 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for SPINK13 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| SPINK13 | 6.11e+01 | -1.02e+00 | 2.35e-01 | -4.35e+00 | 1.33e-05 | 1.73e-04 | KIRP |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| SPINK13 | 9.95e+01 | 2.24e+00 | 6.43e-01 | 3.49e+00 | 4.84e-04 | 2.90e-03 | KIRP |
Top |
Sex-biased somatic mutation for SPINK13 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for SPINK13 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg01391299 | chr5:148268749 | CGI:chr5:148383720-148384103 | UTR,promoter,exon,gene body | 4.50e-01 | 3.36e-01 | 2.02e+00 | 4.30e-02 | 4.72e-02 | 1.14e-01 |
| KIRC | cg10598168 | chr5:148268392 | CGI:chr5:148383720-148384103 | UTR,promoter,exon,gene body | 7.95e-01 | 6.73e-01 | 4.73e+00 | 2.29e-06 | 1.71e-05 | 1.23e-01 |
| ACC | cg10598168 | chr5:148268392 | CGI:chr5:148383720-148384103 | UTR,promoter,exon,gene body | 6.30e-01 | 7.50e-01 | -2.08e+00 | 3.77e-02 | 4.49e-02 | -1.20e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg01907761 | chr5:148268246 | CGI:chr5:148383720-148384103 | UTR,promoter,exon,gene body | 3.41e-01 | 6.98e-01 | -3.48e+00 | 5.03e-04 | 8.46e-04 | -3.57e-01 |
| KIRC | cg02292949 | chr5:148268929 | CGI:chr5:148383720-148384103 | promoter,gene body | 6.98e-01 | 8.68e-01 | -4.02e+00 | 5.78e-05 | 1.26e-04 | -1.70e-01 |
| COAD | cg01907761 | chr5:148268246 | CGI:chr5:148383720-148384103 | UTR,promoter,exon,gene body | 4.76e-01 | 8.28e-01 | -2.32e+00 | 2.05e-02 | 2.52e-02 | -3.52e-01 |
| BLCA | cg02292949 | chr5:148268929 | CGI:chr5:148383720-148384103 | promoter,gene body | 7.55e-01 | 8.87e-01 | -2.70e+00 | 6.88e-03 | 1.05e-02 | -1.32e-01 |
| LIHC | cg01907761 | chr5:148268246 | CGI:chr5:148383720-148384103 | UTR,promoter,exon,gene body | 5.31e-01 | 7.38e-01 | 2.41e+00 | 1.62e-02 | 1.86e-02 | -2.07e-01 |
| KIRP | cg01391299 | chr5:148268749 | CGI:chr5:148383720-148384103 | UTR,promoter,exon,gene body | 2.90e-01 | 3.93e-01 | -3.74e+00 | 1.86e-04 | 4.39e-04 | -1.03e-01 |
| CHOL | cg01907761 | chr5:148268246 | CGI:chr5:148383720-148384103 | UTR,promoter,exon,gene body | 4.23e-01 | 6.28e-01 | -2.29e+00 | 2.23e-02 | 3.24e-02 | -2.05e-01 |
| CHOL | cg01391299 | chr5:148268749 | CGI:chr5:148383720-148384103 | UTR,promoter,exon,gene body | 3.86e-01 | 7.32e-01 | -3.54e+00 | 4.02e-04 | 8.32e-03 | -3.46e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUAD | cg01391299 | chr5:148268749 | CGI:chr5:148383720-148384103 | UTR,promoter,exon,gene body | 4.19e-01 | 5.25e-01 | -3.23e+00 | 1.25e-03 | 3.70e-03 | -1.06e-01 |
| HNSC | cg02292949 | chr5:148268929 | CGI:chr5:148383720-148384103 | promoter,gene body | 7.68e-01 | 8.75e-01 | -2.39e+00 | 1.70e-02 | 2.50e-02 | -1.07e-01 |
| BLCA | cg01391299 | chr5:148268749 | CGI:chr5:148383720-148384103 | UTR,promoter,exon,gene body | 3.61e-01 | 5.00e-01 | -2.70e+00 | 6.94e-03 | 1.39e-02 | -1.38e-01 |
Top |
Exon skipping events with PSI in TCGA for SPINK13 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for SPINK13 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for SPINK13 |
| TFs related to SPINK13. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| ACC | ZNF418 | SPINK13 | 4.76e+00 | 9.81e-01 | 4.06e+00 | 1.55e-02 | Male-biased |
| CHOL | ZNF418 | SPINK13 | 4.25e+00 | 7.85e-03 | 5.25e+00 | 9.90e-01 | Female-biased |
| DLBC | ZNF418 | SPINK13 | 4.91e+00 | 9.89e-01 | 3.96e+00 | 7.04e-03 | Male-biased |
| DLBC | ZNF79 | SPINK13 | 4.95e+00 | 9.86e-01 | 4.10e+00 | 1.05e-02 | Male-biased |
| ESCA | ZNF71 | SPINK13 | 4.68e+00 | 9.86e-01 | 3.96e+00 | 9.89e-03 | Male-biased |
| GBM | FOXA1 | SPINK13 | 5.49e+00 | 9.82e-01 | 4.55e+00 | 1.65e-02 | Male-biased |
| GBM | FOXA3 | SPINK13 | 5.67e+00 | 9.80e-01 | 4.77e+00 | 1.87e-02 | Male-biased |
| GBM | STAT2 | SPINK13 | 4.55e+00 | 9.85e-01 | 3.40e+00 | 8.44e-03 | Male-biased |
| GBM | ZNF25 | SPINK13 | 5.59e+00 | 9.88e-01 | 4.51e+00 | 1.09e-02 | Male-biased |
| GBM | ZNF418 | SPINK13 | 5.38e+00 | 9.94e-01 | 3.99e+00 | 4.21e-03 | Male-biased |
| GBM | ZNF79 | SPINK13 | 5.40e+00 | 9.93e-01 | 4.07e+00 | 5.00e-03 | Male-biased |
| MESO | FOXA1 | SPINK13 | 5.09e+00 | 9.96e-01 | 3.36e+00 | 1.77e-03 | Male-biased |
| MESO | FOXA3 | SPINK13 | 5.25e+00 | 9.96e-01 | 3.58e+00 | 2.24e-03 | Male-biased |
| MESO | FOXC1 | SPINK13 | 5.40e+00 | 9.86e-01 | 4.25e+00 | 1.24e-02 | Male-biased |
| MESO | FOXC2 | SPINK13 | 4.51e+00 | 9.90e-01 | 2.97e+00 | 3.31e-03 | Male-biased |
| MESO | FOXF1 | SPINK13 | 5.30e+00 | 9.90e-01 | 4.00e+00 | 7.62e-03 | Male-biased |
| MESO | FOXP2 | SPINK13 | 5.17e+00 | 9.87e-01 | 3.97e+00 | 1.07e-02 | Male-biased |
| MESO | FOXQ1 | SPINK13 | 5.48e+00 | 9.93e-01 | 4.04e+00 | 4.93e-03 | Male-biased |
| MESO | HNF1B | SPINK13 | 6.01e+00 | 9.80e-01 | 4.99e+00 | 1.88e-02 | Male-biased |
| MESO | ONECUT3 | SPINK13 | 5.78e+00 | 9.85e-01 | 4.66e+00 | 1.37e-02 | Male-biased |
| MESO | POU6F2 | SPINK13 | 5.99e+00 | 9.88e-01 | 4.80e+00 | 1.13e-02 | Male-biased |
| MESO | STAT2 | SPINK13 | 3.96e+00 | 9.82e-01 | 2.40e+00 | 2.88e-03 | Male-biased |
| MESO | TEAD3 | SPINK13 | 5.44e+00 | 9.81e-01 | 4.41e+00 | 1.76e-02 | Male-biased |
| MESO | ZKSCAN2 | SPINK13 | 5.40e+00 | 9.94e-01 | 3.92e+00 | 4.32e-03 | Male-biased |
| MESO | ZNF25 | SPINK13 | 5.21e+00 | 9.97e-01 | 3.32e+00 | 9.86e-04 | Male-biased |
| MESO | ZNF418 | SPINK13 | 4.71e+00 | 9.95e-01 | 2.07e+00 | 6.56e-05 | Male-biased |
| MESO | ZNF79 | SPINK13 | 4.87e+00 | 9.96e-01 | 2.90e+00 | 7.14e-04 | Male-biased |
| READ | ZNF418 | SPINK13 | 5.83e+00 | 9.90e-01 | 5.00e+00 | 9.42e-03 | Male-biased |
| SPINK13 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for SPINK13 |
| RBPs related to ES in SPINK13. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| SPINK13 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs17287002 | chr5:141651073:C:T | - | 0.093848925478582 | 0.00604306959854218 | KIRC | Female-baised eQTL |
| rs61749636 | chr5:141654303:T:G | - | 0.093848925478582 | 0.00604306959854218 | KIRC | Female-baised eQTL |
| rs4912750 | chr5:141406877:A:T | - | 0.0836708354957444 | 0.0138195646643749 | KIRC | Female-baised eQTL |
| rs153664 | chr5:142431728:A:G | - | -0.0568218866149737 | 0.0212658832424815 | KIRC | Female-baised eQTL |
| rs17286989 | chr5:141647245:A:C | - | 0.082386374399302 | 0.0219242538830445 | KIRC | Female-baised eQTL |
| rs62380760 | chr5:141604887:G:A | - | 0.0800472294385334 | 0.0232815391184942 | KIRC | Female-baised eQTL |
| rs12522883 | chr5:157096393:G:A | - | 0.0584141039524466 | 0.0270727569666782 | LUAD | Female-baised eQTL |
| rs180757903 | chr5:157096967:T:C | - | 0.0584141039524466 | 0.0270727569666782 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs12109403 | chr5:151608144:G:A | - | 0.0618585721180192 | 0.00303027764207897 | KIRC | Male-baised eQTL |
| rs6886059 | chr5:142888049:G:A | - | 0.0504030853747321 | 0.00609299175788227 | KIRC | Male-baised eQTL |
| rs6892654 | chr5:142889491:G:A | - | 0.0531011891507271 | 0.00729741051802167 | KIRC | Male-baised eQTL |
| rs6886351 | chr5:142886004:A:G | - | 0.0530366503723475 | 0.00746999860447839 | KIRC | Male-baised eQTL |
| rs6879670 | chr5:149842592:C:T | - | 0.052972142859311 | 0.0252672072218362 | KIRC | Male-baised eQTL |
| rs10073108 | chr5:148850014:T:C | - | 0.0432971218678718 | 0.029764474956512 | KIRC | Male-baised eQTL |
| rs75053155 | chr5:153615312:T:A | - | 0.0365093275354697 | 0.0371415291725893 | KIRC | Male-baised eQTL |
| rs923183 | chr5:145227119:A:G | - | 0.0531578682666708 | 0.0481496810175737 | KIRC | Male-baised eQTL |
| rs57813050 | chr5:143484607:A:C | - | 0.0745309174381838 | 5.73679858088423e-05 | LUAD | Male-baised eQTL |
| rs248508 | chr5:141828779:A:G | - | -0.0858952356821805 | 0.000133606104703436 | LUAD | Male-baised eQTL |
| rs248506 | chr5:141829289:A:G | - | -0.0858952356821805 | 0.000133606104703436 | LUAD | Male-baised eQTL |
| rs10463359 | chr5:143487727:T:G | - | 0.0686143976232956 | 0.000221818587670034 | LUAD | Male-baised eQTL |
| rs6880439 | chr5:143488847:C:T | - | 0.0673353588725113 | 0.000308433589549671 | LUAD | Male-baised eQTL |
| rs17100350 | chr5:143489971:C:T | - | 0.0673353588725113 | 0.000308433589549671 | LUAD | Male-baised eQTL |
| rs921017 | chr5:143491250:C:T | - | 0.0673684202885461 | 0.00030965881634615 | LUAD | Male-baised eQTL |
| rs2028831 | chr5:143496286:G:A | - | 0.0652622174451454 | 0.000482105279228014 | LUAD | Male-baised eQTL |
| rs248517 | chr5:141822328:A:C | - | -0.0748226114926814 | 0.00107661295669184 | LUAD | Male-baised eQTL |
| rs171584 | chr5:141821966:C:G | - | -0.0728627818173445 | 0.0012791453256053 | LUAD | Male-baised eQTL |
| rs173570 | chr5:141818466:G:A | - | -0.0711242700225627 | 0.00175570466937782 | LUAD | Male-baised eQTL |
| rs123146 | chr5:141825114:G:C | - | -0.0698652281067381 | 0.00254095291996394 | LUAD | Male-baised eQTL |
| rs57393241 | chr5:142158692:C:T | - | 0.05969052658297 | 0.00356172150705162 | LUAD | Male-baised eQTL |
| rs4705384 | chr5:149812603:T:C | - | 0.0725198801654095 | 0.00500222205523103 | LUAD | Male-baised eQTL |
| rs76390604 | chr5:149818046:T:C | - | 0.0704135860694863 | 0.0067893692032277 | LUAD | Male-baised eQTL |
| rs10491360 | chr5:149818252:T:C | - | 0.0704135860694863 | 0.0067893692032277 | LUAD | Male-baised eQTL |
| rs1368359 | chr5:142749325:A:G | - | 0.0691754979720005 | 0.00731888579312287 | LUAD | Male-baised eQTL |
| rs7732571 | chr5:142141204:C:G | - | 0.0544364592677837 | 0.00895032290361484 | LUAD | Male-baised eQTL |
| rs2043281 | chr5:142143290:A:G | - | 0.0544364592677837 | 0.00895032290361484 | LUAD | Male-baised eQTL |
| rs3850577 | chr5:142147398:C:T | - | 0.0544364592677837 | 0.00895032290361484 | LUAD | Male-baised eQTL |
| rs3911911 | chr5:142147632:C:T | - | 0.0544364592677837 | 0.00895032290361484 | LUAD | Male-baised eQTL |
| rs58625131 | chr5:142158500:T:G | - | 0.0543026665080639 | 0.00935196605218688 | LUAD | Male-baised eQTL |
| rs116557 | chr5:141823794:G:T | - | -0.0608276744803088 | 0.0100949632210348 | LUAD | Male-baised eQTL |
| rs17100330 | chr5:143486999:C:T | - | 0.0664197687441809 | 0.0102986092113649 | LUAD | Male-baised eQTL |
| rs80301208 | chr5:143485492:A:G | - | 0.066394205884819 | 0.0104128439126258 | LUAD | Male-baised eQTL |
| rs1123825 | chr5:144437293:A:G | - | 0.0844386529879279 | 0.0113882271279925 | LUAD | Male-baised eQTL |
| rs6580231 | chr5:142150581:C:A | - | 0.0524725589873909 | 0.011874367860787 | LUAD | Male-baised eQTL |
| rs17100322 | chr5:143481699:A:G | - | 0.0646762598631623 | 0.0132093510753818 | LUAD | Male-baised eQTL |
| rs17100326 | chr5:143483391:C:T | - | 0.0646762598631623 | 0.0132093510753818 | LUAD | Male-baised eQTL |
| rs7733001 | chr5:142136203:G:A | - | 0.051739519116016 | 0.013439267402147 | LUAD | Male-baised eQTL |
| rs112028479 | chr5:142141248:T:C | - | 0.051739519116016 | 0.013439267402147 | LUAD | Male-baised eQTL |
| rs112324272 | chr5:142141421:C:G | - | 0.051739519116016 | 0.013439267402147 | LUAD | Male-baised eQTL |
| rs3850576 | chr5:142144467:T:C | - | 0.051739519116016 | 0.013439267402147 | LUAD | Male-baised eQTL |
| rs7725919 | chr5:142146608:C:A | - | 0.051739519116016 | 0.013439267402147 | LUAD | Male-baised eQTL |
| rs2906084 | chr5:142161591:G:A | - | -0.051611081354311 | 0.0139954617705587 | LUAD | Male-baised eQTL |
| rs55872445 | chr5:142158691:G:T | - | 0.051611081354311 | 0.0139954617705587 | LUAD | Male-baised eQTL |
| rs7721458 | chr5:143483675:C:A | - | 0.0630616056892832 | 0.016448447522319 | LUAD | Male-baised eQTL |
| rs7727031 | chr5:147876357:T:C | - | 0.0545089502994351 | 0.0364096673664487 | LUAD | Male-baised eQTL |
| rs13185299 | chr5:142146055:A:G | - | 0.0454470467264942 | 0.0368024212908671 | LUAD | Male-baised eQTL |
| rs17098069 | chr5:142119870:G:A | - | 0.0454988906058075 | 0.0382949712881709 | LUAD | Male-baised eQTL |
| rs62394188 | chr5:145600299:G:A | - | 0.0629859852644971 | 0.0394763411623754 | LUAD | Male-baised eQTL |
| rs62394211 | chr5:145615940:C:T | - | 0.061064048139178 | 0.0484615306094949 | LUAD | Male-baised eQTL |
| rs79155448 | chr5:145616241:G:A | - | 0.061064048139178 | 0.0484615306094949 | LUAD | Male-baised eQTL |
| rs1821267 | chr5:145616474:G:A | - | 0.061064048139178 | 0.0484615306094949 | LUAD | Male-baised eQTL |
| rs1821269 | chr5:145616626:G:A | - | 0.061064048139178 | 0.0484615306094949 | LUAD | Male-baised eQTL |
| rs7449247 | chr5:145616683:C:A | - | 0.061064048139178 | 0.0484615306094949 | LUAD | Male-baised eQTL |
| rs1835973 | chr5:145617129:T:C | - | 0.061064048139178 | 0.0484615306094949 | LUAD | Male-baised eQTL |
| rs1835974 | chr5:145617157:A:T | - | 0.061064048139178 | 0.0484615306094949 | LUAD | Male-baised eQTL |
| rs62394217 | chr5:145618341:C:T | - | 0.061064048139178 | 0.0484615306094949 | LUAD | Male-baised eQTL |
| rs1897582 | chr5:145622554:A:T | - | 0.061064048139178 | 0.0484615306094949 | LUAD | Male-baised eQTL |
| rs6863005 | chr5:145623370:C:A | - | 0.061064048139178 | 0.0484615306094949 | LUAD | Male-baised eQTL |
| rs4579305 | chr5:145623606:C:T | - | 0.061064048139178 | 0.0484615306094949 | LUAD | Male-baised eQTL |
| rs1433035 | chr5:145623961:G:T | - | 0.061064048139178 | 0.0484615306094949 | LUAD | Male-baised eQTL |
| rs62394224 | chr5:145625309:A:G | - | 0.061064048139178 | 0.0484615306094949 | LUAD | Male-baised eQTL |
| rs77839581 | chr5:145626465:C:T | - | 0.061064048139178 | 0.0484615306094949 | LUAD | Male-baised eQTL |
| rs1865007 | chr5:145629104:C:G | - | 0.0610290908021525 | 0.0486310441529182 | LUAD | Male-baised eQTL |
| rs62392261 | chr5:145631972:A:G | - | 0.0609977842370772 | 0.0489941059904845 | LUAD | Male-baised eQTL |
| rs4339405 | chr5:145623691:C:T | - | 0.0610009091105795 | 0.0491682373510747 | LUAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000214510 |
| CpG Site: cg10598168 | |
| Position to Gene: gene,exon,promoter,UTR | |
| Male Effect: -0.488652545281816 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg10598168 | chr5:148268392 | gene,exon,promoter,UTR | -0.488652545281816 | 9.62887077689688e-58 | -0.8430536841883836 | 1.8838881186107818e-61 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of SPINK13 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
