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Gene: ENSG00000203879

Summary for GDI1

Gene summary

Gene information	Ensembl ID	ENSG00000203879
	Gene symbol	GDI1
	Gene name	GDP dissociation inhibitor 1
	HGNC	4226
	Entrez ID	2664
	Gene type	protein_coding
	Synonyms	GDI1\|RABGDIA\|XAP-4\|OPHN2\|FLJ41411
	UniProtAcc	P31150

Drugs associated with this gene(DrugBank).

Gene ID

Gene Symbol

Drug ID

Drug Name

Drug Type

Cancer therapeutic drugs associated with this gene(NCI).

Gene ID

Gene Name

Drug ID

Drug Name

Drug Type

Cancer

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Structure and expression level for GDI1

AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure.
∗For more information on exon skipping events please check the ExonskipDB database.
∗For more information on exon skipping events please check the CAeditome database.

Landscape of gene expressions across multiple cancer types.

Differentially expressed gene analysis between tumor male and tumor female samples.

Coding Name

Base Mean

log2FoldChange

lfcSE

Stat

P value

P.adjust Value

Cancer Type

Differentially expressed gene analysis between tumor male and normal male samples.

Coding Name

Base Mean

log2FoldChange

lfcSE

Stat

P value

P.adjust Value

Cancer Type

Differentially expressed gene analysis between tumor female and normal female samples.

Coding Name

Base Mean

log2FoldChange

lfcSE

Stat

P value

P.adjust Value

Cancer Type

Top

Sex-biased somatic mutation for GDI1

∗For more information on exon skipping events please check the ExonskipDB database.

Gene ID

Cancer Type

Hugo Symbol

Male

Female

pval

ci.up

ci.low

adjPval

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DNA methylation with beta values for GDI1

Landscape of DNA methylation across multiple cancer types.

Differentially expressed CpG sites between male tumor and female tumor patients.

Cancer Type	CpG Site	Position	CpG Island	Position to Gene	ave1	ave2	wilcoxon.w	wilcoxon.p	padj	dBeta
BRCA	cg18796341	chrX:154436557	CGI:chrX:154436415-154437719	promoter	3.47e-01	1.04e-01	4.01e+00	6.03e-05	1.12e-03	2.43e-01
BRCA	cg05222959	chrX:154436757	CGI:chrX:154436415-154437719	promoter	2.21e-01	2.31e-02	5.14e+00	2.77e-07	1.16e-05	1.98e-01
BRCA	cg22951728	chrX:154436559	CGI:chrX:154436415-154437719	promoter	3.48e-01	1.09e-01	3.96e+00	7.44e-05	1.30e-03	2.39e-01
BRCA	cg13240932	chrX:154437278	CGI:chrX:154436415-154437719	promoter,exon,CDS,gene body	3.74e-01	1.37e-02	5.16e+00	2.43e-07	1.16e-05	3.60e-01
BRCA	cg22850802	chrX:154437351	CGI:chrX:154436415-154437719	promoter,gene body	3.64e-01	1.23e-02	5.16e+00	2.43e-07	1.16e-05	3.52e-01
BRCA	cg01430241	chrX:154437368	CGI:chrX:154436415-154437719	promoter,gene body	4.94e-01	5.42e-02	5.16e+00	2.43e-07	1.16e-05	4.39e-01
BRCA	cg06919398	chrX:154437453	CGI:chrX:154436415-154437719	promoter,gene body	4.72e-01	6.35e-02	5.15e+00	2.62e-07	1.16e-05	4.08e-01
BRCA	cg11860160	chrX:154438863	CGI:chrX:154436415-154437719	promoter,gene body,CDS,UTR,exon	7.22e-01	8.56e-01	-3.40e+00	6.82e-04	7.41e-03	-1.34e-01
LGG	cg18796341	chrX:154436557	CGI:chrX:154436415-154437719	promoter	4.32e-01	2.63e-01	9.10e+00	9.06e-20	6.21e-19	1.69e-01
LGG	cg05222959	chrX:154436757	CGI:chrX:154436415-154437719	promoter	2.31e-01	2.18e-02	1.98e+01	3.60e-87	2.64e-85	2.09e-01
LGG	cg22951728	chrX:154436559	CGI:chrX:154436415-154437719	promoter	4.08e-01	1.54e-01	1.32e+01	5.18e-40	4.79e-39	2.54e-01
LGG	cg13240932	chrX:154437278	CGI:chrX:154436415-154437719	promoter,exon,CDS,gene body	3.86e-01	1.55e-02	1.96e+01	7.75e-86	2.63e-84	3.70e-01
LGG	cg22850802	chrX:154437351	CGI:chrX:154436415-154437719	promoter,gene body	3.44e-01	1.28e-02	1.98e+01	4.03e-87	2.64e-85	3.31e-01
LGG	cg16227684	chrX:154436516	CGI:chrX:154436415-154437719	promoter	5.09e-01	2.12e-01	1.55e+01	2.64e-54	3.05e-53	2.96e-01
LGG	cg01430241	chrX:154437368	CGI:chrX:154436415-154437719	promoter,gene body	4.95e-01	4.86e-02	1.98e+01	3.52e-87	2.64e-85	4.47e-01
LGG	cg06919398	chrX:154437453	CGI:chrX:154436415-154437719	promoter,gene body	4.59e-01	5.41e-02	1.98e+01	3.72e-87	2.64e-85	4.05e-01
LUSC	cg18796341	chrX:154436557	CGI:chrX:154436415-154437719	promoter	3.13e-01	8.44e-02	1.29e+01	5.06e-38	7.75e-37	2.28e-01
LUSC	cg05222959	chrX:154436757	CGI:chrX:154436415-154437719	promoter	2.11e-01	2.24e-02	1.44e+01	3.19e-47	1.27e-45	1.89e-01
LUSC	cg22951728	chrX:154436559	CGI:chrX:154436415-154437719	promoter	2.94e-01	4.17e-02	1.36e+01	2.03e-42	3.61e-41	2.53e-01
LUSC	cg13240932	chrX:154437278	CGI:chrX:154436415-154437719	promoter,exon,CDS,gene body	3.56e-01	1.74e-02	1.45e+01	1.70e-47	1.26e-45	3.38e-01
LUSC	cg22850802	chrX:154437351	CGI:chrX:154436415-154437719	promoter,gene body	3.26e-01	1.51e-02	1.45e+01	2.10e-47	1.26e-45	3.11e-01
LUSC	cg16227684	chrX:154436516	CGI:chrX:154436415-154437719	promoter	4.60e-01	1.42e-01	1.31e+01	4.01e-39	6.34e-38	3.18e-01
LUSC	cg01430241	chrX:154437368	CGI:chrX:154436415-154437719	promoter,gene body	4.51e-01	5.29e-02	1.45e+01	2.13e-47	1.26e-45	3.99e-01
LUSC	cg06919398	chrX:154437453	CGI:chrX:154436415-154437719	promoter,gene body	4.36e-01	5.88e-02	1.45e+01	1.29e-47	1.26e-45	3.77e-01
SKCM	cg18796341	chrX:154436557	CGI:chrX:154436415-154437719	promoter	3.35e-01	6.99e-02	1.62e+01	8.12e-59	1.41e-57	2.65e-01
SKCM	cg05222959	chrX:154436757	CGI:chrX:154436415-154437719	promoter	2.42e-01	2.14e-02	1.79e+01	1.20e-71	3.88e-70	2.21e-01
SKCM	cg22951728	chrX:154436559	CGI:chrX:154436415-154437719	promoter	3.27e-01	3.81e-02	1.68e+01	1.76e-63	3.51e-62	2.89e-01
SKCM	cg13240932	chrX:154437278	CGI:chrX:154436415-154437719	promoter,exon,CDS,gene body	3.66e-01	1.44e-02	1.82e+01	3.17e-74	3.59e-72	3.52e-01
SKCM	cg22850802	chrX:154437351	CGI:chrX:154436415-154437719	promoter,gene body	3.07e-01	1.25e-02	1.82e+01	3.47e-74	3.59e-72	2.94e-01
SKCM	cg16227684	chrX:154436516	CGI:chrX:154436415-154437719	promoter	4.58e-01	1.32e-01	1.67e+01	2.43e-62	4.64e-61	3.27e-01
SKCM	cg01430241	chrX:154437368	CGI:chrX:154436415-154437719	promoter,gene body	4.64e-01	5.06e-02	1.82e+01	3.34e-74	3.59e-72	4.13e-01
SKCM	cg06919398	chrX:154437453	CGI:chrX:154436415-154437719	promoter,gene body	4.02e-01	5.48e-02	1.81e+01	3.59e-73	1.62e-71	3.47e-01
COAD	cg11860160	chrX:154438863	CGI:chrX:154436415-154437719	promoter,gene body,CDS,UTR,exon	7.67e-01	8.77e-01	-1.05e+01	1.41e-25	1.83e-24	-1.10e-01
STAD	cg18796341	chrX:154436557	CGI:chrX:154436415-154437719	promoter	3.48e-01	1.53e-01	1.00e+01	1.33e-23	1.75e-22	1.95e-01
STAD	cg05222959	chrX:154436757	CGI:chrX:154436415-154437719	promoter	2.18e-01	2.21e-02	1.51e+01	9.55e-52	5.28e-50	1.96e-01
STAD	cg22951728	chrX:154436559	CGI:chrX:154436415-154437719	promoter	3.50e-01	1.11e-01	1.11e+01	1.14e-28	1.70e-27	2.39e-01
STAD	cg13240932	chrX:154437278	CGI:chrX:154436415-154437719	promoter,exon,CDS,gene body	3.85e-01	1.45e-02	1.52e+01	6.81e-52	4.96e-50	3.70e-01
STAD	cg22850802	chrX:154437351	CGI:chrX:154436415-154437719	promoter,gene body	3.58e-01	1.58e-02	1.51e+01	1.51e-51	7.10e-50	3.42e-01
STAD	cg16227684	chrX:154436516	CGI:chrX:154436415-154437719	promoter	5.15e-01	2.33e-01	9.77e+00	1.46e-22	1.85e-21	2.82e-01
STAD	cg01430241	chrX:154437368	CGI:chrX:154436415-154437719	promoter,gene body	4.88e-01	5.69e-02	1.51e+01	2.71e-51	1.13e-49	4.31e-01
STAD	cg06919398	chrX:154437453	CGI:chrX:154436415-154437719	promoter,gene body	4.62e-01	5.40e-02	1.52e+01	6.81e-52	4.96e-50	4.08e-01
LIHC	cg24857545	chrX:154436129	CGI:chrX:154436415-154437719	promoter	8.15e-01	9.17e-01	-9.89e+00	4.54e-23	1.29e-21	-1.02e-01
LIHC	cg11860160	chrX:154438863	CGI:chrX:154436415-154437719	promoter,gene body,CDS,UTR,exon	7.05e-01	8.52e-01	-1.02e+01	2.96e-24	8.66e-23	-1.47e-01
SARC	cg18796341	chrX:154436557	CGI:chrX:154436415-154437719	promoter	3.02e-01	1.15e-01	9.07e+00	1.17e-19	1.59e-18	1.87e-01
SARC	cg05222959	chrX:154436757	CGI:chrX:154436415-154437719	promoter	1.89e-01	2.28e-02	1.29e+01	6.25e-38	2.57e-36	1.67e-01
SARC	cg22951728	chrX:154436559	CGI:chrX:154436415-154437719	promoter	2.82e-01	6.96e-02	9.84e+00	7.42e-23	1.20e-21	2.12e-01
SARC	cg13240932	chrX:154437278	CGI:chrX:154436415-154437719	promoter,exon,CDS,gene body	3.20e-01	1.75e-02	1.35e+01	1.17e-41	8.39e-40	3.03e-01
SARC	cg22850802	chrX:154437351	CGI:chrX:154436415-154437719	promoter,gene body	2.71e-01	1.55e-02	1.36e+01	3.69e-42	3.15e-40	2.56e-01
SARC	cg16227684	chrX:154436516	CGI:chrX:154436415-154437719	promoter	4.62e-01	1.48e-01	1.02e+01	3.05e-24	5.42e-23	3.14e-01
SARC	cg01430241	chrX:154437368	CGI:chrX:154436415-154437719	promoter,gene body	4.39e-01	5.04e-02	1.38e+01	1.99e-43	6.68e-41	3.89e-01
SARC	cg06919398	chrX:154437453	CGI:chrX:154436415-154437719	promoter,gene body	3.94e-01	5.63e-02	1.31e+01	2.21e-39	1.05e-37	3.38e-01
PCPG	cg18796341	chrX:154436557	CGI:chrX:154436415-154437719	promoter	2.50e-01	4.93e-02	1.04e+01	1.77e-25	2.29e-24	2.01e-01
PCPG	cg05222959	chrX:154436757	CGI:chrX:154436415-154437719	promoter	1.78e-01	2.25e-02	1.14e+01	3.08e-30	6.89e-29	1.55e-01
PCPG	cg22951728	chrX:154436559	CGI:chrX:154436415-154437719	promoter	1.90e-01	2.60e-02	1.08e+01	5.28e-27	7.52e-26	1.64e-01
PCPG	cg13240932	chrX:154437278	CGI:chrX:154436415-154437719	promoter,exon,CDS,gene body	3.42e-01	1.48e-02	1.16e+01	3.83e-31	1.92e-29	3.28e-01
PCPG	cg22850802	chrX:154437351	CGI:chrX:154436415-154437719	promoter,gene body	1.76e-01	1.27e-02	1.15e+01	1.96e-30	4.79e-29	1.63e-01
PCPG	cg16227684	chrX:154436516	CGI:chrX:154436415-154437719	promoter	3.47e-01	9.96e-02	1.06e+01	3.88e-26	5.19e-25	2.47e-01
PCPG	cg01430241	chrX:154437368	CGI:chrX:154436415-154437719	promoter,gene body	4.90e-01	4.96e-02	1.16e+01	3.83e-31	1.92e-29	4.40e-01
PCPG	cg06919398	chrX:154437453	CGI:chrX:154436415-154437719	promoter,gene body	3.35e-01	6.25e-02	1.16e+01	3.83e-31	1.92e-29	2.72e-01
PCPG	cg11860160	chrX:154438863	CGI:chrX:154436415-154437719	promoter,gene body,CDS,UTR,exon	4.43e-01	2.56e-01	8.31e+00	9.98e-17	7.72e-16	1.87e-01
PAAD	cg18796341	chrX:154436557	CGI:chrX:154436415-154437719	promoter	3.27e-01	1.04e-01	9.16e+00	5.26e-20	7.67e-19	2.22e-01
PAAD	cg05222959	chrX:154436757	CGI:chrX:154436415-154437719	promoter	2.11e-01	2.18e-02	1.15e+01	2.03e-30	1.01e-28	1.89e-01
PAAD	cg22951728	chrX:154436559	CGI:chrX:154436415-154437719	promoter	3.12e-01	6.48e-02	1.01e+01	4.48e-24	8.12e-23	2.47e-01
PAAD	cg13240932	chrX:154437278	CGI:chrX:154436415-154437719	promoter,exon,CDS,gene body	3.95e-01	1.47e-02	1.15e+01	2.03e-30	1.01e-28	3.80e-01
PAAD	cg22850802	chrX:154437351	CGI:chrX:154436415-154437719	promoter,gene body	3.28e-01	1.31e-02	1.15e+01	2.03e-30	1.01e-28	3.15e-01
PAAD	cg16227684	chrX:154436516	CGI:chrX:154436415-154437719	promoter	4.70e-01	1.81e-01	8.82e+00	1.15e-18	1.54e-17	2.89e-01
PAAD	cg01430241	chrX:154437368	CGI:chrX:154436415-154437719	promoter,gene body	4.88e-01	4.81e-02	1.15e+01	2.03e-30	1.01e-28	4.40e-01
PAAD	cg06919398	chrX:154437453	CGI:chrX:154436415-154437719	promoter,gene body	4.45e-01	5.73e-02	1.15e+01	2.03e-30	1.01e-28	3.87e-01
READ	cg18796341	chrX:154436557	CGI:chrX:154436415-154437719	promoter	3.11e-01	1.01e-01	7.01e+00	2.44e-12	2.34e-11	2.09e-01
READ	cg05222959	chrX:154436757	CGI:chrX:154436415-154437719	promoter	2.05e-01	1.89e-02	8.49e+00	2.15e-17	4.34e-16	1.86e-01
READ	cg22951728	chrX:154436559	CGI:chrX:154436415-154437719	promoter	3.18e-01	5.73e-02	7.47e+00	7.96e-14	8.27e-13	2.60e-01
READ	cg13240932	chrX:154437278	CGI:chrX:154436415-154437719	promoter,exon,CDS,gene body	3.42e-01	1.34e-02	8.49e+00	2.15e-17	4.34e-16	3.29e-01
READ	cg22850802	chrX:154437351	CGI:chrX:154436415-154437719	promoter,gene body	3.58e-01	1.10e-02	8.49e+00	2.15e-17	4.34e-16	3.47e-01
READ	cg16227684	chrX:154436516	CGI:chrX:154436415-154437719	promoter	4.53e-01	1.71e-01	7.17e+00	7.44e-13	7.34e-12	2.83e-01
READ	cg01430241	chrX:154437368	CGI:chrX:154436415-154437719	promoter,gene body	4.42e-01	4.55e-02	8.49e+00	2.15e-17	4.34e-16	3.97e-01
READ	cg06919398	chrX:154437453	CGI:chrX:154436415-154437719	promoter,gene body	4.48e-01	4.87e-02	8.49e+00	2.15e-17	4.34e-16	3.99e-01
READ	cg11860160	chrX:154438863	CGI:chrX:154436415-154437719	promoter,gene body,CDS,UTR,exon	7.61e-01	8.71e-01	-5.62e+00	1.90e-08	1.31e-07	-1.10e-01
GBM	cg18796341	chrX:154436557	CGI:chrX:154436415-154437719	promoter	3.69e-01	4.25e-02	6.71e+00	1.97e-11	3.03e-10	3.26e-01
GBM	cg05222959	chrX:154436757	CGI:chrX:154436415-154437719	promoter	2.72e-01	2.04e-02	6.75e+00	1.48e-11	2.64e-10	2.52e-01
GBM	cg22951728	chrX:154436559	CGI:chrX:154436415-154437719	promoter	3.81e-01	2.30e-02	6.75e+00	1.48e-11	2.64e-10	3.58e-01
GBM	cg13240932	chrX:154437278	CGI:chrX:154436415-154437719	promoter,exon,CDS,gene body	4.01e-01	1.36e-02	6.75e+00	1.48e-11	2.64e-10	3.88e-01
GBM	cg22850802	chrX:154437351	CGI:chrX:154436415-154437719	promoter,gene body	4.51e-01	1.21e-02	6.75e+00	1.48e-11	2.64e-10	4.39e-01
GBM	cg16227684	chrX:154436516	CGI:chrX:154436415-154437719	promoter	4.99e-01	8.07e-02	6.74e+00	1.63e-11	2.71e-10	4.19e-01
GBM	cg01430241	chrX:154437368	CGI:chrX:154436415-154437719	promoter,gene body	5.49e-01	5.64e-02	6.75e+00	1.48e-11	2.64e-10	4.93e-01
GBM	cg06919398	chrX:154437453	CGI:chrX:154436415-154437719	promoter,gene body	5.54e-01	6.16e-02	6.75e+00	1.48e-11	2.64e-10	4.92e-01
ESCA	cg18796341	chrX:154436557	CGI:chrX:154436415-154437719	promoter	3.45e-01	1.26e-01	5.85e+00	5.00e-09	4.12e-08	2.19e-01
ESCA	cg05222959	chrX:154436757	CGI:chrX:154436415-154437719	promoter	1.91e-01	2.21e-02	7.59e+00	3.22e-14	6.84e-13	1.69e-01
ESCA	cg22951728	chrX:154436559	CGI:chrX:154436415-154437719	promoter	3.31e-01	6.45e-02	6.74e+00	1.64e-11	1.62e-10	2.67e-01
ESCA	cg13240932	chrX:154437278	CGI:chrX:154436415-154437719	promoter,exon,CDS,gene body	3.49e-01	1.63e-02	7.60e+00	2.88e-14	6.84e-13	3.33e-01
ESCA	cg22850802	chrX:154437351	CGI:chrX:154436415-154437719	promoter,gene body	3.18e-01	1.47e-02	7.59e+00	3.22e-14	6.84e-13	3.03e-01
ESCA	cg16227684	chrX:154436516	CGI:chrX:154436415-154437719	promoter	4.91e-01	2.01e-01	5.90e+00	3.74e-09	3.12e-08	2.90e-01
ESCA	cg01430241	chrX:154437368	CGI:chrX:154436415-154437719	promoter,gene body	4.55e-01	4.92e-02	7.59e+00	3.22e-14	6.84e-13	4.05e-01
ESCA	cg06919398	chrX:154437453	CGI:chrX:154436415-154437719	promoter,gene body	4.23e-01	5.70e-02	7.57e+00	3.60e-14	6.84e-13	3.66e-01
LAML	cg18796341	chrX:154436557	CGI:chrX:154436415-154437719	promoter	5.36e-01	3.54e-01	3.64e+00	2.73e-04	8.77e-04	1.82e-01
LAML	cg05222959	chrX:154436757	CGI:chrX:154436415-154437719	promoter	3.04e-01	3.09e-02	1.01e+01	6.71e-24	2.74e-22	2.73e-01
LAML	cg22951728	chrX:154436559	CGI:chrX:154436415-154437719	promoter	5.53e-01	2.95e-01	4.76e+00	1.90e-06	7.03e-06	2.57e-01
LAML	cg13240932	chrX:154437278	CGI:chrX:154436415-154437719	promoter,exon,CDS,gene body	4.17e-01	2.30e-02	1.02e+01	1.90e-24	2.70e-22	3.94e-01
LAML	cg22850802	chrX:154437351	CGI:chrX:154436415-154437719	promoter,gene body	4.23e-01	2.38e-02	1.01e+01	6.45e-24	2.74e-22	3.99e-01
LAML	cg16227684	chrX:154436516	CGI:chrX:154436415-154437719	promoter	6.11e-01	4.02e-01	4.13e+00	3.65e-05	1.25e-04	2.08e-01
LAML	cg01430241	chrX:154437368	CGI:chrX:154436415-154437719	promoter,gene body	5.41e-01	5.60e-02	1.01e+01	5.30e-24	2.72e-22	4.85e-01
LAML	cg06919398	chrX:154437453	CGI:chrX:154436415-154437719	promoter,gene body	5.16e-01	7.07e-02	1.01e+01	8.16e-24	2.82e-22	4.46e-01
THYM	cg18796341	chrX:154436557	CGI:chrX:154436415-154437719	promoter	4.06e-01	2.17e-01	7.25e+00	4.32e-13	2.32e-12	1.89e-01
THYM	cg05222959	chrX:154436757	CGI:chrX:154436415-154437719	promoter	1.97e-01	2.24e-02	9.07e+00	1.14e-19	1.18e-18	1.75e-01
THYM	cg22951728	chrX:154436559	CGI:chrX:154436415-154437719	promoter	3.30e-01	6.75e-02	9.06e+00	1.32e-19	1.35e-18	2.63e-01
THYM	cg13240932	chrX:154437278	CGI:chrX:154436415-154437719	promoter,exon,CDS,gene body	3.58e-01	1.39e-02	9.40e+00	5.48e-21	1.00e-19	3.44e-01
THYM	cg22850802	chrX:154437351	CGI:chrX:154436415-154437719	promoter,gene body	2.75e-01	1.31e-02	9.40e+00	5.48e-21	1.00e-19	2.61e-01
THYM	cg16227684	chrX:154436516	CGI:chrX:154436415-154437719	promoter	5.45e-01	3.19e-01	7.04e+00	1.96e-12	9.95e-12	2.25e-01
THYM	cg01430241	chrX:154437368	CGI:chrX:154436415-154437719	promoter,gene body	4.32e-01	4.41e-02	9.40e+00	5.48e-21	1.00e-19	3.88e-01
THYM	cg06919398	chrX:154437453	CGI:chrX:154436415-154437719	promoter,gene body	4.25e-01	6.44e-02	9.39e+00	5.77e-21	1.00e-19	3.60e-01
MESO	cg18796341	chrX:154436557	CGI:chrX:154436415-154437719	promoter	2.69e-01	5.76e-02	5.58e+00	2.38e-08	2.42e-07	2.11e-01
MESO	cg05222959	chrX:154436757	CGI:chrX:154436415-154437719	promoter	1.69e-01	2.33e-02	6.06e+00	1.36e-09	2.54e-08	1.45e-01
MESO	cg22951728	chrX:154436559	CGI:chrX:154436415-154437719	promoter	2.32e-01	3.58e-02	5.92e+00	3.15e-09	4.26e-08	1.96e-01
MESO	cg13240932	chrX:154437278	CGI:chrX:154436415-154437719	promoter,exon,CDS,gene body	2.97e-01	1.48e-02	6.06e+00	1.36e-09	2.54e-08	2.82e-01
MESO	cg22850802	chrX:154437351	CGI:chrX:154436415-154437719	promoter,gene body	2.46e-01	1.42e-02	6.05e+00	1.46e-09	2.54e-08	2.32e-01
MESO	cg16227684	chrX:154436516	CGI:chrX:154436415-154437719	promoter	4.22e-01	1.38e-01	5.62e+00	1.95e-08	2.02e-07	2.84e-01
MESO	cg01430241	chrX:154437368	CGI:chrX:154436415-154437719	promoter,gene body	3.83e-01	5.04e-02	6.06e+00	1.36e-09	2.54e-08	3.32e-01
MESO	cg06919398	chrX:154437453	CGI:chrX:154436415-154437719	promoter,gene body	3.93e-01	6.86e-02	6.05e+00	1.46e-09	2.54e-08	3.25e-01
UVM	cg18796341	chrX:154436557	CGI:chrX:154436415-154437719	promoter	2.20e-01	2.98e-02	7.28e+00	3.37e-13	4.33e-12	1.90e-01
UVM	cg22951728	chrX:154436559	CGI:chrX:154436415-154437719	promoter	1.78e-01	2.61e-02	6.04e+00	1.57e-09	1.09e-08	1.51e-01
UVM	cg13240932	chrX:154437278	CGI:chrX:154436415-154437719	promoter,exon,CDS,gene body	2.64e-01	1.38e-02	7.64e+00	2.21e-14	9.97e-13	2.50e-01
UVM	cg22850802	chrX:154437351	CGI:chrX:154436415-154437719	promoter,gene body	2.15e-01	1.28e-02	7.54e+00	4.68e-14	1.11e-12	2.02e-01
UVM	cg16227684	chrX:154436516	CGI:chrX:154436415-154437719	promoter	3.47e-01	7.86e-02	7.06e+00	1.72e-12	1.79e-11	2.69e-01
UVM	cg01430241	chrX:154437368	CGI:chrX:154436415-154437719	promoter,gene body	3.86e-01	4.17e-02	7.50e+00	6.29e-14	1.28e-12	3.44e-01
UVM	cg06919398	chrX:154437453	CGI:chrX:154436415-154437719	promoter,gene body	3.56e-01	5.59e-02	6.89e+00	5.55e-12	5.21e-11	3.00e-01
ACC	cg01430241	chrX:154437368	CGI:chrX:154436415-154437719	promoter,gene body	4.60e-01	4.61e-02	7.47e+00	8.02e-14	2.68e-12	4.14e-01
ACC	cg05222959	chrX:154436757	CGI:chrX:154436415-154437719	promoter	2.30e-01	2.04e-02	7.43e+00	1.09e-13	2.87e-12	2.10e-01
ACC	cg06919398	chrX:154437453	CGI:chrX:154436415-154437719	promoter,gene body	4.03e-01	4.40e-02	7.18e+00	7.03e-13	1.28e-11	3.59e-01
ACC	cg11860160	chrX:154438863	CGI:chrX:154436415-154437719	promoter,gene body,CDS,UTR,exon	6.73e-01	7.95e-01	-3.76e+00	1.73e-04	1.12e-03	-1.22e-01
ACC	cg13240932	chrX:154437278	CGI:chrX:154436415-154437719	promoter,exon,CDS,gene body	3.88e-01	1.33e-02	7.47e+00	8.02e-14	2.68e-12	3.75e-01
ACC	cg22850802	chrX:154437351	CGI:chrX:154436415-154437719	promoter,gene body	2.91e-01	1.12e-02	7.30e+00	2.89e-13	6.02e-12	2.79e-01
ACC	cg22951728	chrX:154436559	CGI:chrX:154436415-154437719	promoter	4.61e-01	2.54e-01	3.34e+00	8.28e-04	4.51e-03	2.07e-01
KICH	cg13240932	chrX:154437278	CGI:chrX:154436415-154437719	promoter,exon,CDS,gene body	2.16e-01	1.78e-02	6.59e+00	4.45e-11	1.88e-09	1.98e-01
KICH	cg22850802	chrX:154437351	CGI:chrX:154436415-154437719	promoter,gene body	1.43e-01	1.51e-02	5.78e+00	7.26e-09	8.57e-08	1.28e-01
KICH	cg16227684	chrX:154436516	CGI:chrX:154436415-154437719	promoter	3.56e-01	1.91e-01	4.24e+00	2.19e-05	1.70e-04	1.66e-01
KICH	cg01430241	chrX:154437368	CGI:chrX:154436415-154437719	promoter,gene body	3.17e-01	5.51e-02	6.61e+00	3.72e-11	1.88e-09	2.61e-01
KICH	cg06919398	chrX:154437453	CGI:chrX:154436415-154437719	promoter,gene body	2.38e-01	5.69e-02	6.52e+00	6.97e-11	1.88e-09	1.81e-01
DLBC	cg18796341	chrX:154436557	CGI:chrX:154436415-154437719	promoter	4.12e-01	1.66e-01	3.79e+00	1.53e-04	6.87e-04	2.45e-01
DLBC	cg05222959	chrX:154436757	CGI:chrX:154436415-154437719	promoter	1.85e-01	3.45e-02	5.38e+00	7.46e-08	7.44e-07	1.50e-01
DLBC	cg22951728	chrX:154436559	CGI:chrX:154436415-154437719	promoter	4.31e-01	1.13e-01	4.47e+00	7.84e-06	5.69e-05	3.17e-01
DLBC	cg13240932	chrX:154437278	CGI:chrX:154436415-154437719	promoter,exon,CDS,gene body	3.34e-01	1.41e-02	5.92e+00	3.26e-09	5.31e-08	3.20e-01
DLBC	cg22850802	chrX:154437351	CGI:chrX:154436415-154437719	promoter,gene body	2.98e-01	1.24e-02	5.92e+00	3.26e-09	5.31e-08	2.86e-01
DLBC	cg16227684	chrX:154436516	CGI:chrX:154436415-154437719	promoter	5.11e-01	2.72e-01	3.37e+00	7.44e-04	2.76e-03	2.40e-01
DLBC	cg01430241	chrX:154437368	CGI:chrX:154436415-154437719	promoter,gene body	3.96e-01	4.40e-02	5.92e+00	3.26e-09	5.31e-08	3.52e-01
DLBC	cg06919398	chrX:154437453	CGI:chrX:154436415-154437719	promoter,gene body	3.99e-01	5.15e-02	5.92e+00	3.26e-09	5.31e-08	3.47e-01
CHOL	cg18796341	chrX:154436557	CGI:chrX:154436415-154437719	promoter	3.83e-01	1.15e-01	3.57e+00	3.63e-04	1.62e-03	2.68e-01
CHOL	cg05222959	chrX:154436757	CGI:chrX:154436415-154437719	promoter	2.17e-01	2.45e-02	4.65e+00	3.35e-06	2.61e-05	1.93e-01
CHOL	cg22951728	chrX:154436559	CGI:chrX:154436415-154437719	promoter	4.08e-01	6.53e-02	4.17e+00	3.04e-05	1.78e-04	3.43e-01
CHOL	cg13240932	chrX:154437278	CGI:chrX:154436415-154437719	promoter,exon,CDS,gene body	3.72e-01	1.74e-02	5.09e+00	3.51e-07	4.92e-06	3.55e-01
CHOL	cg22850802	chrX:154437351	CGI:chrX:154436415-154437719	promoter,gene body	3.63e-01	1.58e-02	4.81e+00	1.53e-06	1.32e-05	3.47e-01
CHOL	cg16227684	chrX:154436516	CGI:chrX:154436415-154437719	promoter	5.62e-01	2.13e-01	3.98e+00	6.91e-05	3.67e-04	3.49e-01
CHOL	cg01430241	chrX:154437368	CGI:chrX:154436415-154437719	promoter,gene body	4.96e-01	6.02e-02	5.09e+00	3.51e-07	4.92e-06	4.36e-01
CHOL	cg06919398	chrX:154437453	CGI:chrX:154436415-154437719	promoter,gene body	5.08e-01	7.19e-02	5.00e+00	5.79e-07	6.26e-06	4.36e-01

Differentially expressed CpG sites between male tumor and male normal patients.

Cancer Type	CpG Site	Position	CpG Island	Position to Gene	ave1	ave2	wilcoxon.w	wilcoxon.p	padj	dBeta
KIRC	cg11860160	chrX:154438863	CGI:chrX:154436415-154437719	promoter,gene body,CDS,UTR,exon	4.51e-01	3.36e-01	2.86e+00	4.19e-03	5.52e-03	1.14e-01
LUAD	cg11860160	chrX:154438863	CGI:chrX:154436415-154437719	promoter,gene body,CDS,UTR,exon	8.31e-01	7.30e-01	4.34e+00	1.40e-05	5.51e-05	1.01e-01
THCA	cg11860160	chrX:154438863	CGI:chrX:154436415-154437719	promoter,gene body,CDS,UTR,exon	7.55e-01	6.13e-01	3.73e+00	1.94e-04	9.57e-04	1.42e-01
HNSC	cg18796341	chrX:154436557	CGI:chrX:154436415-154437719	promoter	1.88e-01	3.42e-02	5.36e+00	8.51e-08	8.58e-07	1.54e-01
HNSC	cg16227684	chrX:154436516	CGI:chrX:154436415-154437719	promoter	2.71e-01	9.33e-02	4.46e+00	8.33e-06	3.27e-05	1.78e-01
COAD	cg18796341	chrX:154436557	CGI:chrX:154436415-154437719	promoter	1.50e-01	3.56e-02	2.95e+00	3.17e-03	5.72e-03	1.14e-01
COAD	cg16227684	chrX:154436516	CGI:chrX:154436415-154437719	promoter	2.49e-01	8.54e-02	3.80e+00	1.43e-04	4.67e-04	1.63e-01
COAD	cg11860160	chrX:154438863	CGI:chrX:154436415-154437719	promoter,gene body,CDS,UTR,exon	8.77e-01	7.73e-01	4.30e+00	1.72e-05	8.87e-05	1.04e-01
BLCA	cg11860160	chrX:154438863	CGI:chrX:154436415-154437719	promoter,gene body,CDS,UTR,exon	8.04e-01	5.74e-01	4.36e+00	1.32e-05	1.10e-04	2.31e-01
CHOL	cg18796341	chrX:154436557	CGI:chrX:154436415-154437719	promoter	1.15e-01	3.63e-01	-2.65e+00	7.96e-03	1.92e-02	-2.48e-01
CHOL	cg22951728	chrX:154436559	CGI:chrX:154436415-154437719	promoter	6.53e-02	2.13e-01	-2.95e+00	3.19e-03	1.32e-02	-1.48e-01
CHOL	cg16227684	chrX:154436516	CGI:chrX:154436415-154437719	promoter	2.13e-01	6.12e-01	-3.17e+00	1.52e-03	1.07e-02	-3.99e-01

Differentially expressed CpG sites between female tumor and female normal patients.

Cancer Type	CpG Site	Position	CpG Island	Position to Gene	ave1	ave2	wilcoxon.w	wilcoxon.p	padj	dBeta
KIRC	cg22850802	chrX:154437351	CGI:chrX:154436415-154437719	promoter,gene body	3.53e-01	2.51e-01	2.40e+00	1.64e-02	2.36e-02	1.02e-01
LIHC	cg01430241	chrX:154437368	CGI:chrX:154436415-154437719	promoter,gene body	4.31e-01	5.55e-01	-3.98e+00	6.97e-05	2.93e-04	-1.24e-01

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Exon skipping events with PSI in TCGA for GDI1

∗Please access ExonSkipDB for exon skipping annotation.

Landscape of exon skipping events across multiple cancer types.

Differentially expressed exon skipping events between male tumor and female tumor patients.

Cancer Type

Exon Skipping

ave.female_T

ave.female_N

wilcoxon.w

wilcoxon.p

padj

dPSI

Differentially expressed exon skipping events between male tumor and male normal patients.

Cancer Type

Exon Skipping

ave.female_T

ave.female_N

wilcoxon.w

wilcoxon.p

padj

dPSI

Differentially expressed exon skipping events between female tumor and female normal patients.

Cancer Type

Exon Skipping

ave.female_T

ave.female_N

wilcoxon.w

wilcoxon.p

padj

dPSI

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RNA A-to-I editing events in TCGA for GDI1

∗Please access CAeditome for RNA editing annotation.

Differentially expressed RNA editing events between male tumor and female tumor patients.

Cancer Type

Transcript

Editing

ave.male_T

ave.female_T

wilcoxon.w

wilcoxon.p

p_adj

dFre

Differentially expressed RNA editing events between male tumor and male normal patients.

Cancer Type

Transcript

Editing

ave.male_T

ave.female_T

wilcoxon.w

wilcoxon.p

p_adj

dFre

Differentially expressed RNA editing events between female tumor and female normal patients.

Cancer Type

Transcript

Editing

ave.male_T

ave.female_T

wilcoxon.w

wilcoxon.p

p_adj

dFre

Protein coding RNA editing(s).

Editing Position

Variant Type

Gene Symbol

Transcript ID

NTchange

AAchange

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Sex-biased TF-Gene network for GDI1

TFs related to GDI1.
∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98.
∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98.

Cancer Type

Target Gene

Male Edge Score

Male Edge Threshold

Female Edge Score

Female Edge Threshold

Type

GDI1 related gene.
∗Only the gene encode TF might with this result.
∗For more information please check Sex-biased TF-Coding gene network.

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Sex-biased RBP-ES network for GDI1

RBPs related to ES in GDI1.
∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98.
∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98.

Cancer Type	RBP	Target ES	Male Edge Score	Male Edge Threshold	Female Edge Score	Female Edge Threshold	Type
UVM	SRSF1	exon_skip_513269	8.93e+00	9.92e-01	8.54e+00	2.87e-03	Male-biased
DLBC	IGF2BP1	exon_skip_513260	7.62e+00	9.86e-01	7.19e+00	3.54e-03	Male-biased
THCA	SRSF1	exon_skip_513269	9.06e+00	9.86e-01	8.77e+00	1.03e-02	Male-biased
KIRC	SRSF1	exon_skip_513269	8.88e+00	9.87e-01	8.56e+00	8.79e-03	Male-biased

GDI1 related ES.
∗Only the gene encode RBP might with this result.
∗For more information please check Sex-biased RBP-ES network in cancer.

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Sex-biased CeRNA regulation of gene

Sex-biased CeRNA regulation of gene.

Gene ID

ceRNA(lncRNA-miRNA-mRNA)

Group

Cancer Type

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Sex-biased eQTL regulation of gene

Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).

eQTL

Description

Male-specific eQTL regulation.

SNP ID

SNP Info

Position to Gene

Effect Score

FDR

Cancer Type

Biased Type

Female-specific eQTL regulation.

SNP ID

SNP Info

Position to Gene

Effect Score

FDR

Cancer Type

Biased Type

Opposite sex-biased eQTL regulation.

SNP ID

SNP Info

Position to Gene

Male Effect

Male FDR

Female Effect

Female FDR

Sex-biased Gene in Cancer

Cancer Type

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Sex-biased eQTM regulation of gene

Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table).

eQTM	Description
	Gene ID: ENSG00000203879
	CpG Site: cg16227684
	Position to Gene: promoter
	Male Effect: -
	Female Effect: -0.266565333549571
	Gene ID: ENSG00000203879
	CpG Site: cg16227684
	Position to Gene: promoter
	Male Effect: -
	Female Effect: -0.315248086771469

Male-specific eQTM regulation.

CpG Site

CpG Postion

Position to Gene

Effect Score

FDR

Cor.r

Cor.Pvalue

Cancer Type

Female-specific eQTM regulation.

CpG Site	CpG Postion	Position to Gene	Effect Score	FDR	Cor.r	Cor.Pvalue	Cancer Type
cg16227684	chrX:154436516	promoter	-0.266565333549571	5.68672170007075e-09	-0.6897300702414662	1.488507392522099e-12	PAAD
cg16227684	chrX:154436516	promoter	-0.315248086771469	5.17194273050194e-06	-0.35546563684773524	5.21081469967382e-09	LUAD

Opposite sex-biased eQTM regulation.

CpG Site

CpG Postion

CpG Island

Position to Gene

Male Effect

Male FDR

Female Effect

Female FDR

Male Cor

Male P-value

Female Cor

Female P-value

Sex-biased Coding Gene

Cancer Type

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Sex-biased sQTL regulation of gene

Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).

sQTL

Description

Male-specific sQTL regulation.

ES ID

Skipped Exon

ORF Anno

SNP ID

SNP Info

SNP Position to ES

Effect Score

FDR

Cancer Type

Biased Type

Female-specific sQTL regulation.

ES ID

Skipped Exon

ORF Anno

SNP ID

SNP Info

SNP Position to ES

Effect Score

FDR

Cancer Type

Biased Type

Opposite sex-biased sQTL regulation.

ES ID

Skipped Exon

ORF Anno

SNP ID

SNP Info

SNP Position to ES

Male Effect

Male FDR

Female Effect

Female FDR

Cancer Type

Top

Sex-biased sQTM regulation of gene

Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).

sQTM

Description

Male-specific sQTM regulation.

EX ID

Skipped Exon

CPG Site

CPG Position

Position to EX Events

Effect Score

FDR

Cor.r

Cor.Pvalue

ORF_anno

Cancer Type

Female-specific sQTM regulation.

EX ID

Skipped Exon

CPG Site

CPG Position

Position to EX Events

Effect Score

FDR

Cor.r

Cor.Pvalue

ORF_anno

Cancer Type

Opposite sex-biased sQTM regulation.

EX ID

EX Info

Skipped Exon

CPG Site

CPG Position

CPG Island

Position to EX Events

Male Effect

Male FDR

Female Effect

Female FDR

Male Correlation

Male P-value

Female Correlation

Female P-value

ORF_anno

Cancer Type

Top

Related disease information of GDI1

Diseases associated with this gene (DisGeNET).

Gene ID	Gene Symbol	Disease ID	Disease Name	Number of PMID	Source
ENSG00000203879	GDI1	C0019193	Hepatitis, Toxic	1	CTD_human
ENSG00000203879	GDI1	C0860207	Drug-Induced Liver Disease	1	CTD_human
ENSG00000203879	GDI1	C1136249	Mental Retardation, X-Linked	2	CTD_human
ENSG00000203879	GDI1	C1262760	Hepatitis, Drug-Induced	1	CTD_human
ENSG00000203879	GDI1	C1862939	AMYOTROPHIC LATERAL SCLEROSIS 1	1	CTD_human
ENSG00000203879	GDI1	C1862941	Amyotrophic Lateral Sclerosis, Sporadic	1	CTD_human
ENSG00000203879	GDI1	C3658290	Drug-Induced Acute Liver Injury	1	CTD_human
ENSG00000203879	GDI1	C3887939	MENTAL RETARDATION, X-LINKED 41	1	CTD_human
ENSG00000203879	GDI1	C4277682	Chemical and Drug Induced Liver Injury	1	CTD_human
ENSG00000203879	GDI1	C4279912	Chemically-Induced Liver Toxicity	1	CTD_human
ENSG00000203879	GDI1	C4551993	Amyotrophic Lateral Sclerosis, Familial	1	CTD_human

	Gene summary
	Gene structure and Gene expression level
	Sex-biased somatic mutation
	DNA methylation with beta values in gene
	Exon skipping events with PSI in TCGA
	RNA A-to-I editing events in TCGA
	Sex-biased TF-Gene network of gene
	Sex-biased RBP-ES network of gene
	Sex-biased CeRNA regulation of gene
	Sex-biased eQTL regulation of gene
	Sex-biased eQTM regulation of gene
	Sex-biased sQTL regulation of gene
	Sex-biased sQTM regulation of gene
	Related disease information of gene