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Gene: ENSG00000198719 |
Summary for DLL1 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000198719 | Gene symbol | DLL1 |
| Gene name | delta like canonical Notch ligand 1 | |
| HGNC | 2908 | |
| Entrez ID | 28514 | |
| Gene type | protein_coding | |
| Synonyms | DLL1| | |
| UniProtAcc | O00548 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for DLL1 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| DLL1 | 2.18e+02 | -2.02e+00 | 3.40e-01 | -5.94e+00 | 2.80e-09 | 1.49e-08 | KIRP |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| DLL1 | 1.22e+03 | 1.15e+00 | 2.33e-01 | 4.93e+00 | 8.25e-07 | 3.04e-06 | KIRC |
Top |
Sex-biased somatic mutation for DLL1 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for DLL1 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LIHC | cg26200580 | chr6:170306185 | CGI:chr6:170306153-170307122 | promoter,gene body | 2.43e-01 | 3.87e-01 | -4.91e+00 | 9.01e-07 | 1.23e-05 | -1.44e-01 |
Top |
Exon skipping events with PSI in TCGA for DLL1 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for DLL1 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for DLL1 |
| TFs related to DLL1. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| DLL1 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for DLL1 |
| RBPs related to ES in DLL1. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| DLL1 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000198719 | LINC02137,hsa-mir-500b,DLL1 | Male-specific ceRNA | TCGA-KIRP |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs73239071 | chr6:169606037:A:C | - | 0.184192518235026 | 0.000413126939743601 | SARC | Female-baised eQTL |
| rs73239077 | chr6:169610725:A:G | - | 0.184192518235026 | 0.000413126939743601 | SARC | Female-baised eQTL |
| rs3817869 | chr6:169624640:T:C | - | 0.184054491393053 | 0.000424696863205185 | SARC | Female-baised eQTL |
| rs1033458 | chr6:169594698:C:T | - | 0.184923048889552 | 0.00062062743460966 | SARC | Female-baised eQTL |
| rs4451137 | chr6:169585974:C:T | - | 0.184257854371348 | 0.000660182236726727 | SARC | Female-baised eQTL |
| rs12111411 | chr6:169626315:G:A | - | 0.162006022510725 | 0.00193693992061386 | SARC | Female-baised eQTL |
| rs77336201 | chr6:169542241:T:G | - | 0.17612540378321 | 0.0133736567062279 | SARC | Female-baised eQTL |
| rs78919990 | chr6:169611645:C:T | - | 0.168928837896819 | 0.017561987376106 | SARC | Female-baised eQTL |
| rs80297937 | chr6:169615288:G:A | - | 0.168928837896819 | 0.017561987376106 | SARC | Female-baised eQTL |
| rs16888175 | chr6:169577323:C:T | - | 0.138697409839776 | 0.0188350948498521 | SARC | Female-baised eQTL |
| rs58321158 | chr6:169635195:G:A | - | 0.150815156412357 | 0.022184829201334 | SARC | Female-baised eQTL |
| rs79846353 | chr6:169494739:C:T | - | 0.165916297557785 | 0.0229052422364499 | SARC | Female-baised eQTL |
| rs16888119 | chr6:169537141:C:T | - | 0.162594951651344 | 0.0306266157307085 | SARC | Female-baised eQTL |
| rs78099962 | chr6:169534888:T:C | - | 0.162379644559451 | 0.0313365981855182 | SARC | Female-baised eQTL |
| rs6924775 | chr6:166261136:C:T | - | -0.180136179785461 | 0.00233984195599935 | LUSC | Female-baised eQTL |
| rs4272194 | chr6:162958756:A:G | - | -0.0463967750767674 | 0.0311208999292967 | LUAD | Female-baised eQTL |
| rs4374806 | chr6:162959836:T:C | - | -0.0453918131046358 | 0.0362208510935229 | LUAD | Female-baised eQTL |
| rs1606676 | chr6:162932361:C:T | - | -0.0432483927140208 | 0.0422403027861356 | LUAD | Female-baised eQTL |
| rs2151653 | chr6:162931326:C:T | - | -0.0429681221984553 | 0.0459320687773747 | LUAD | Female-baised eQTL |
| rs9365517 | chr6:162968724:T:G | - | -0.0442958965586019 | 0.0488555927441598 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs114055053 | chr6:163696559:T:C | - | 0.166555885821674 | 6.01512916357546e-05 | GBM | Male-baised eQTL |
| rs9355104 | chr6:168917238:T:C | - | -0.158548860362411 | 0.000171260544283272 | GBM | Male-baised eQTL |
| rs1072852 | chr6:169468451:T:C | - | 0.137048945998847 | 0.00133986605642277 | GBM | Male-baised eQTL |
| rs111350414 | chr6:169505625:T:A | - | 0.136646443041197 | 0.00144609136700881 | GBM | Male-baised eQTL |
| rs73013528 | chr6:163376275:C:T | - | 0.124948421521699 | 0.00592627946840271 | GBM | Male-baised eQTL |
| rs9356351 | chr6:165168258:C:T | - | 0.110228980515373 | 0.0182553407126592 | GBM | Male-baised eQTL |
| rs11969444 | chr6:164433914:A:G | - | 0.106303983376947 | 0.0244240440989884 | GBM | Male-baised eQTL |
| rs56330409 | chr6:162259888:G:A | - | 0.106907863724373 | 0.025613575298085 | GBM | Male-baised eQTL |
| rs12203820 | chr6:166950023:T:A | - | 0.103038286057547 | 0.0317645549076314 | GBM | Male-baised eQTL |
| rs6456002 | chr6:165559169:G:C | - | 0.118593491768934 | 0.00301889660190104 | KIRC | Male-baised eQTL |
| rs1407660 | chr6:163654062:G:A | - | -0.116263415099033 | 0.00526002600427679 | KIRC | Male-baised eQTL |
| rs4709002 | chr6:163654208:G:A | - | -0.116263415099033 | 0.00526002600427679 | KIRC | Male-baised eQTL |
| rs1407659 | chr6:163653951:G:A | - | -0.104131368957101 | 0.0143204583645944 | KIRC | Male-baised eQTL |
| rs7738188 | chr6:162392632:T:C | - | 0.0505808469968514 | 0.0184489718679402 | KIRC | Male-baised eQTL |
| rs9365413 | chr6:162387136:G:A | - | 0.0501900379817603 | 0.018862284849722 | KIRC | Male-baised eQTL |
| rs1407661 | chr6:163656853:C:T | - | -0.100929145706771 | 0.0247885523175433 | KIRC | Male-baised eQTL |
| rs672986 | chr6:165534799:A:G | - | -0.0672048151111406 | 0.0332236219440769 | KIRC | Male-baised eQTL |
| rs1407658 | chr6:163653810:T:C | - | -0.0916753079839897 | 0.0473636246332619 | KIRC | Male-baised eQTL |
| rs112701017 | chr6:168349347:C:T | - | 0.0646337064020402 | 0.00630530402144609 | BLCA | Male-baised eQTL |
| rs57703590 | chr6:168347041:G:T | - | 0.0646094757053108 | 0.0063248795309582 | BLCA | Male-baised eQTL |
| rs4628069 | chr6:168348108:G:C | - | 0.0646094757053108 | 0.0063248795309582 | BLCA | Male-baised eQTL |
| rs4452616 | chr6:168348231:G:A | - | 0.0646094757053108 | 0.0063248795309582 | BLCA | Male-baised eQTL |
| rs4464762 | chr6:168348425:C:A | - | 0.0646094757053108 | 0.0063248795309582 | BLCA | Male-baised eQTL |
| rs4305697 | chr6:168348840:A:T | - | 0.0646094757053108 | 0.0063248795309582 | BLCA | Male-baised eQTL |
| rs4358592 | chr6:168348911:G:A | - | 0.0646094757053108 | 0.0063248795309582 | BLCA | Male-baised eQTL |
| rs4272192 | chr6:168348932:T:G | - | 0.0646094757053108 | 0.0063248795309582 | BLCA | Male-baised eQTL |
| rs4292502 | chr6:168348962:G:A | - | 0.0646094757053108 | 0.0063248795309582 | BLCA | Male-baised eQTL |
| rs75740452 | chr6:168349389:G:A | - | 0.0646094757053108 | 0.0063248795309582 | BLCA | Male-baised eQTL |
| rs79638817 | chr6:168349624:C:T | - | 0.0646094757053108 | 0.0063248795309582 | BLCA | Male-baised eQTL |
| rs57210650 | chr6:168350033:G:C | - | 0.0646094757053108 | 0.0063248795309582 | BLCA | Male-baised eQTL |
| rs80000613 | chr6:168349333:G:A | - | 0.0645690582062881 | 0.00637277661846653 | BLCA | Male-baised eQTL |
| rs80112829 | chr6:168351066:T:C | - | 0.0644884315861146 | 0.00649962828435911 | BLCA | Male-baised eQTL |
| rs79827962 | chr6:168351315:G:A | - | 0.0644884315861146 | 0.00649962828435911 | BLCA | Male-baised eQTL |
| rs74328459 | chr6:168354064:T:G | - | 0.0621840564516452 | 0.00928655974144133 | BLCA | Male-baised eQTL |
| rs77351260 | chr6:168352726:C:T | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs76517129 | chr6:168352733:G:A | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs79534145 | chr6:168352799:A:T | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs78990904 | chr6:168352923:T:C | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs185128817 | chr6:168353108:C:T | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs79667085 | chr6:168353203:C:T | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs74316879 | chr6:168353408:G:A | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs112381651 | chr6:168353520:C:A | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs79227316 | chr6:168353585:A:G | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs79716137 | chr6:168353694:C:A | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs76767648 | chr6:168353797:T:C | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs77786937 | chr6:168353870:T:C | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs78329686 | chr6:168353951:A:G | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs77810461 | chr6:168354060:T:G | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs112589898 | chr6:168354210:T:C | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs111414032 | chr6:168354307:C:T | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs112228978 | chr6:168354328:G:T | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs112506031 | chr6:168354362:G:A | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs80247432 | chr6:168354444:T:G | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs79921877 | chr6:168354670:T:C | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs76604770 | chr6:168354860:C:T | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs112872127 | chr6:168355360:A:T | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs74617237 | chr6:168355707:C:A | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs79892079 | chr6:168355733:T:C | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs112381501 | chr6:168355992:C:T | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs74831917 | chr6:168356265:A:G | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs76029950 | chr6:168356272:A:G | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs79744650 | chr6:168356310:C:T | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs75329950 | chr6:168356488:C:T | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs112712915 | chr6:168356534:T:A | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs115282405 | chr6:168356612:C:T | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs77231652 | chr6:168359089:G:C | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs75200382 | chr6:168359155:T:G | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs74923497 | chr6:168359684:G:A | - | 0.0619822645159133 | 0.00969597109235518 | BLCA | Male-baised eQTL |
| rs75539827 | chr6:168354592:C:T | - | 0.0619424992756898 | 0.0097595014573058 | BLCA | Male-baised eQTL |
| rs140277687 | chr6:168358974:C:T | - | 0.0619424992756898 | 0.0097595014573058 | BLCA | Male-baised eQTL |
| rs78963309 | chr6:168359235:T:C | - | 0.0619424992756898 | 0.0097595014573058 | BLCA | Male-baised eQTL |
| rs115903173 | chr6:168356615:A:G | - | 0.0619057530397456 | 0.00989409450184373 | BLCA | Male-baised eQTL |
| rs76648233 | chr6:168359281:C:A | - | 0.0618406704078584 | 0.0100155061715195 | BLCA | Male-baised eQTL |
| rs79516962 | chr6:168359324:C:G | - | 0.0617465220084974 | 0.0102057795837182 | BLCA | Male-baised eQTL |
| rs76611061 | chr6:168359981:G:T | - | 0.0617465220084974 | 0.0102057795837182 | BLCA | Male-baised eQTL |
| rs75974958 | chr6:168415747:G:A | - | 0.0601575385032394 | 0.0158700084463803 | BLCA | Male-baised eQTL |
| rs61454292 | chr6:168415922:G:C | - | 0.0601575385032394 | 0.0158700084463803 | BLCA | Male-baised eQTL |
| rs3893205 | chr6:168416242:C:T | - | 0.0583681615127833 | 0.0201267786873862 | BLCA | Male-baised eQTL |
| rs9355094 | chr6:168846558:G:A | - | -0.0820661836021447 | 0.00797141003006464 | LUAD | Male-baised eQTL |
| rs4708503 | chr6:168848022:A:G | - | 0.0796622869790865 | 0.0108089560025033 | LUAD | Male-baised eQTL |
| rs10447372 | chr6:166077074:T:G | - | 0.0495419945120726 | 0.0141412828396193 | COAD | Male-baised eQTL |
| rs56333241 | chr6:166079015:A:C | - | 0.0493713616063775 | 0.0148952205111813 | COAD | Male-baised eQTL |
| rs35739771 | chr6:166069051:C:T | - | 0.0484002841329668 | 0.0216193079681333 | COAD | Male-baised eQTL |
| rs4588666 | chr6:166069175:T:A | - | 0.0484002841329668 | 0.0216193079681333 | COAD | Male-baised eQTL |
| rs80286599 | chr6:166070455:C:G | - | 0.0484002841329668 | 0.0216193079681333 | COAD | Male-baised eQTL |
| rs75300567 | chr6:166072069:C:T | - | 0.0483656668682596 | 0.0229304179863615 | COAD | Male-baised eQTL |
| rs10946118 | chr6:166076178:G:A | - | 0.0444802154317012 | 0.0259243251813671 | COAD | Male-baised eQTL |
| rs77481423 | chr6:165026157:C:T | - | 0.0660965776667695 | 0.037859371321956 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000198719 |
| CpG Site: cg14347219 | |
| Position to Gene: gene | |
| Male Effect: -0.409052638476349 | |
| Female Effect: - | |
 | Gene ID: ENSG00000198719 |
| CpG Site: cg06432036 | |
| Position to Gene: gene,exon,CDS | |
| Male Effect: -0.367852105361837 | |
| Female Effect: - | |
 | Gene ID: ENSG00000198719 |
| CpG Site: cg13494348 | |
| Position to Gene: gene | |
| Male Effect: -0.367852105361837 | |
| Female Effect: - | |
 | Gene ID: ENSG00000198719 |
| CpG Site: cg15931921 | |
| Position to Gene: gene | |
| Male Effect: -0.367852105361837 | |
| Female Effect: - | |
 | Gene ID: ENSG00000198719 |
| CpG Site: cg15931921 | |
| Position to Gene: gene | |
| Male Effect: -0.289939654312525 | |
| Female Effect: - | |
 | Gene ID: ENSG00000198719 |
| CpG Site: cg15931921 | |
| Position to Gene: gene | |
| Male Effect: -0.35347919823739 | |
| Female Effect: - | |
 | Gene ID: ENSG00000198719 |
| CpG Site: cg27614489 | |
| Position to Gene: gene,exon,CDS | |
| Male Effect: -0.346954982456997 | |
| Female Effect: - | |
 | Gene ID: ENSG00000198719 |
| CpG Site: cg11519760 | |
| Position to Gene: gene,exon,CDS | |
| Male Effect: -0.346954982456997 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg14347219 | chr6:170288810 | gene | -0.409052638476349 | 1.50914459918995e-22 | -0.8298186901350473 | 4.65655271094859e-26 | PAAD |
| cg06432036 | chr6:170286297 | gene,exon,CDS | -0.367852105361837 | 3.6950436924775e-06 | -0.532574701652946 | 1.6563662801797613e-08 | PAAD |
| cg13494348 | chr6:170287768 | gene | -0.367852105361837 | 3.6950436924775e-06 | -0.532574701652946 | 1.6563662801797613e-08 | PAAD |
| cg15931921 | chr6:170288500 | gene | -0.367852105361837 | 3.6950436924775e-06 | -0.532574701652946 | 1.6563662801797613e-08 | PAAD |
| cg15931921 | chr6:170288500 | gene | -0.289939654312525 | 1.04002327024997e-08 | -0.4439520432687188 | 4.077575431447171e-11 | KIRP |
| cg15931921 | chr6:170288500 | gene | -0.35347919823739 | 3.22945163968274e-08 | -0.4270214958235498 | 2.6873523080688756e-11 | LUAD |
| cg27614489 | chr6:170283990 | gene,exon,CDS | -0.346954982456997 | 1.04948630510215e-16 | -0.4937804773563256 | 3.756691122766522e-20 | BLCA |
| cg11519760 | chr6:170288406 | gene,exon,CDS | -0.346954982456997 | 1.04948630510215e-16 | -0.4937804773563256 | 3.756691122766522e-20 | BLCA |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of DLL1 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000198719 | DLL1 | C0006118 | Brain Neoplasms | 1 | CTD_human |
| ENSG00000198719 | DLL1 | C0006142 | Malignant neoplasm of breast | 1 | CTD_human |
| ENSG00000198719 | DLL1 | C0153633 | Malignant neoplasm of brain | 1 | CTD_human |
| ENSG00000198719 | DLL1 | C0496899 | Benign neoplasm of brain, unspecified | 1 | CTD_human |
| ENSG00000198719 | DLL1 | C0678222 | Breast Carcinoma | 1 | CTD_human |
| ENSG00000198719 | DLL1 | C0750974 | Brain Tumor, Primary | 1 | CTD_human |
| ENSG00000198719 | DLL1 | C0750977 | Recurrent Brain Neoplasm | 1 | CTD_human |
| ENSG00000198719 | DLL1 | C0750979 | Primary malignant neoplasm of brain | 1 | CTD_human |
| ENSG00000198719 | DLL1 | C1257931 | Mammary Neoplasms, Human | 1 | CTD_human |
| ENSG00000198719 | DLL1 | C1458155 | Mammary Neoplasms | 1 | CTD_human |
| ENSG00000198719 | DLL1 | C1527390 | Neoplasms, Intracranial | 1 | CTD_human |
| ENSG00000198719 | DLL1 | C4704874 | Mammary Carcinoma, Human | 1 | CTD_human |
