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Gene: ENSG00000197757 |
Summary for HOXC6 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000197757 | Gene symbol | HOXC6 |
| Gene name | homeobox C6 | |
| HGNC | 5128 | |
| Entrez ID | 3223 | |
| Gene type | protein_coding | |
| Synonyms | HOXC6| | |
| UniProtAcc | P09630 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for HOXC6 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| HOXC6 | 4.69e+02 | 1.87e+00 | 4.33e-01 | 4.32e+00 | 1.54e-05 | 2.18e-04 | ESCA |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for HOXC6 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for HOXC6 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRP | cg10662314 | chr12:53990882 | CGI:chr12:53994041-53994628 | promoter,gene body | 4.72e-01 | 3.54e-01 | 2.84e+00 | 4.54e-03 | 1.31e-02 | 1.18e-01 |
| DLBC | cg10662314 | chr12:53990882 | CGI:chr12:53994041-53994628 | promoter,gene body | 6.26e-01 | 3.96e-01 | 2.46e+00 | 1.38e-02 | 2.82e-02 | 2.30e-01 |
| DLBC | cg05412137 | chr12:53990960 | CGI:chr12:53994041-53994628 | promoter,gene body | 4.65e-01 | 3.13e-01 | 2.34e+00 | 1.94e-02 | 3.44e-02 | 1.52e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg19898108 | chr12:53989908 | CGI:chr12:53984912-53986318 | promoter | 2.27e-01 | 3.33e-01 | -3.44e+00 | 5.92e-04 | 9.78e-04 | -1.06e-01 |
| HNSC | cg19310604 | chr12:53989605 | CGI:chr12:53984912-53986318 | promoter | 1.95e-01 | 7.34e-02 | 1.97e+00 | 4.83e-02 | 4.85e-02 | 1.22e-01 |
| HNSC | cg06193958 | chr12:53989855 | CGI:chr12:53984912-53986318 | promoter | 3.25e-01 | 1.26e-01 | 3.74e+00 | 1.86e-04 | 4.36e-04 | 1.99e-01 |
| HNSC | cg19898108 | chr12:53989908 | CGI:chr12:53984912-53986318 | promoter | 5.60e-01 | 3.75e-01 | 3.56e+00 | 3.68e-04 | 7.78e-04 | 1.85e-01 |
| LUSC | cg10662314 | chr12:53990882 | CGI:chr12:53994041-53994628 | promoter,gene body | 4.52e-01 | 3.65e-02 | 3.91e+00 | 9.07e-05 | 6.71e-04 | 4.16e-01 |
| LUSC | cg06193958 | chr12:53989855 | CGI:chr12:53984912-53986318 | promoter | 2.53e-01 | 6.11e-02 | 2.57e+00 | 1.03e-02 | 1.41e-02 | 1.91e-01 |
| LUSC | cg16527095 | chr12:53989894 | CGI:chr12:53984912-53986318 | promoter | 2.13e-01 | 5.63e-02 | 2.69e+00 | 7.05e-03 | 1.06e-02 | 1.57e-01 |
| LUSC | cg19898108 | chr12:53989908 | CGI:chr12:53984912-53986318 | promoter | 4.97e-01 | 2.11e-01 | 3.10e+00 | 1.94e-03 | 4.09e-03 | 2.86e-01 |
| LUSC | cg05412137 | chr12:53990960 | CGI:chr12:53994041-53994628 | promoter,gene body | 3.93e-01 | 1.32e-01 | 3.16e+00 | 1.57e-03 | 3.54e-03 | 2.61e-01 |
| LUSC | cg03905819 | chr12:53991491 | CGI:chr12:53994041-53994628 | promoter,gene body | 4.00e-01 | 1.44e-01 | 3.72e+00 | 1.98e-04 | 9.67e-04 | 2.57e-01 |
| LUSC | cg08053137 | chr12:53991652 | CGI:chr12:53994041-53994628 | promoter,gene body | 4.42e-01 | 2.20e-01 | 2.88e+00 | 3.94e-03 | 6.84e-03 | 2.22e-01 |
| LUSC | cg18771937 | chr12:53991733 | CGI:chr12:53994041-53994628 | promoter,gene body | 5.40e-01 | 3.05e-01 | 3.60e+00 | 3.14e-04 | 1.25e-03 | 2.34e-01 |
| LUSC | cg14679255 | chr12:53991742 | CGI:chr12:53994041-53994628 | promoter,gene body | 5.49e-01 | 3.05e-01 | 3.68e+00 | 2.34e-04 | 1.06e-03 | 2.44e-01 |
| LUSC | cg16400495 | chr12:53991841 | CGI:chr12:53994041-53994628 | promoter,gene body | 3.24e-01 | 1.65e-01 | 2.91e+00 | 3.66e-03 | 6.47e-03 | 1.59e-01 |
| BLCA | cg08053137 | chr12:53991652 | CGI:chr12:53994041-53994628 | promoter,gene body | 3.75e-01 | 5.59e-01 | -2.92e+00 | 3.56e-03 | 6.20e-03 | -1.83e-01 |
| BLCA | cg18771937 | chr12:53991733 | CGI:chr12:53994041-53994628 | promoter,gene body | 5.51e-01 | 6.68e-01 | -2.05e+00 | 4.07e-02 | 4.26e-02 | -1.17e-01 |
| ESCA | cg19310604 | chr12:53989605 | CGI:chr12:53984912-53986318 | promoter | 1.82e-01 | 5.52e-02 | 2.46e+00 | 1.38e-02 | 3.76e-02 | 1.27e-01 |
| ESCA | cg16527095 | chr12:53989894 | CGI:chr12:53984912-53986318 | promoter | 2.19e-01 | 6.68e-02 | 2.18e+00 | 2.90e-02 | 4.34e-02 | 1.52e-01 |
| ESCA | cg05412137 | chr12:53990960 | CGI:chr12:53994041-53994628 | promoter,gene body | 4.49e-01 | 2.35e-01 | 2.08e+00 | 3.71e-02 | 4.58e-02 | 2.15e-01 |
| ESCA | cg03905819 | chr12:53991491 | CGI:chr12:53994041-53994628 | promoter,gene body | 4.68e-01 | 1.97e-01 | 3.48e+00 | 4.93e-04 | 3.37e-02 | 2.71e-01 |
| ESCA | cg08053137 | chr12:53991652 | CGI:chr12:53994041-53994628 | promoter,gene body | 5.45e-01 | 2.73e-01 | 2.89e+00 | 3.87e-03 | 3.38e-02 | 2.72e-01 |
| ESCA | cg18771937 | chr12:53991733 | CGI:chr12:53994041-53994628 | promoter,gene body | 5.96e-01 | 4.31e-01 | 2.64e+00 | 8.27e-03 | 3.56e-02 | 1.65e-01 |
| ESCA | cg14679255 | chr12:53991742 | CGI:chr12:53994041-53994628 | promoter,gene body | 6.00e-01 | 4.44e-01 | 2.05e+00 | 3.99e-02 | 4.66e-02 | 1.55e-01 |
| ESCA | cg16400495 | chr12:53991841 | CGI:chr12:53994041-53994628 | promoter,gene body | 4.13e-01 | 2.20e-01 | 2.81e+00 | 4.96e-03 | 3.43e-02 | 1.93e-01 |
| CHOL | cg10662314 | chr12:53990882 | CGI:chr12:53994041-53994628 | promoter,gene body | 3.69e-01 | 4.50e-02 | 2.51e+00 | 1.22e-02 | 2.39e-02 | 3.24e-01 |
| CHOL | cg03905819 | chr12:53991491 | CGI:chr12:53994041-53994628 | promoter,gene body | 3.56e-01 | 1.21e-01 | 2.95e+00 | 3.19e-03 | 1.32e-02 | 2.35e-01 |
| CHOL | cg08053137 | chr12:53991652 | CGI:chr12:53994041-53994628 | promoter,gene body | 3.67e-01 | 1.27e-01 | 2.43e+00 | 1.50e-02 | 2.65e-02 | 2.40e-01 |
| CHOL | cg18771937 | chr12:53991733 | CGI:chr12:53994041-53994628 | promoter,gene body | 5.77e-01 | 2.97e-01 | 3.10e+00 | 1.96e-03 | 1.07e-02 | 2.80e-01 |
| CHOL | cg14679255 | chr12:53991742 | CGI:chr12:53994041-53994628 | promoter,gene body | 6.08e-01 | 2.88e-01 | 3.54e+00 | 4.02e-04 | 8.32e-03 | 3.20e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg18771937 | chr12:53991733 | CGI:chr12:53994041-53994628 | promoter,gene body | 5.65e-01 | 4.57e-01 | 2.20e+00 | 2.75e-02 | 3.33e-02 | 1.08e-01 |
| KIRC | cg14679255 | chr12:53991742 | CGI:chr12:53994041-53994628 | promoter,gene body | 6.02e-01 | 4.50e-01 | 2.87e+00 | 4.15e-03 | 9.81e-03 | 1.52e-01 |
| KIRC | cg16400495 | chr12:53991841 | CGI:chr12:53994041-53994628 | promoter,gene body | 3.07e-01 | 2.02e-01 | 2.00e+00 | 4.59e-02 | 4.71e-02 | 1.06e-01 |
| LUAD | cg16400495 | chr12:53991841 | CGI:chr12:53994041-53994628 | promoter,gene body | 2.72e-01 | 1.52e-01 | 2.29e+00 | 2.20e-02 | 2.77e-02 | 1.20e-01 |
| COAD | cg08053137 | chr12:53991652 | CGI:chr12:53994041-53994628 | promoter,gene body | 4.51e-01 | 5.69e-01 | -2.25e+00 | 2.46e-02 | 3.01e-02 | -1.18e-01 |
| LIHC | cg18771937 | chr12:53991733 | CGI:chr12:53994041-53994628 | promoter,gene body | 4.27e-01 | 2.85e-01 | 2.00e+00 | 4.54e-02 | 4.62e-02 | 1.42e-01 |
| LIHC | cg14679255 | chr12:53991742 | CGI:chr12:53994041-53994628 | promoter,gene body | 4.41e-01 | 2.84e-01 | 2.06e+00 | 3.90e-02 | 4.10e-02 | 1.57e-01 |
Top |
Exon skipping events with PSI in TCGA for HOXC6 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for HOXC6 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for HOXC6 |
| TFs related to HOXC6. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| BLCA | PLAGL2 | HOXC6 | 4.12e+00 | 9.84e-01 | 3.01e+00 | 3.31e-03 | Male-biased |
| BLCA | ZNF28 | HOXC6 | 3.97e+00 | 9.80e-01 | 2.76e+00 | 2.35e-03 | Male-biased |
| DLBC | PRDM6 | HOXC6 | 3.22e+00 | 5.62e-03 | 4.26e+00 | 9.85e-01 | Female-biased |
| DLBC | ZNF182 | HOXC6 | 3.23e+00 | 7.24e-03 | 4.21e+00 | 9.82e-01 | Female-biased |
| DLBC | ZNF22 | HOXC6 | 3.19e+00 | 6.72e-03 | 4.19e+00 | 9.82e-01 | Female-biased |
| DLBC | ZNF235 | HOXC6 | 3.40e+00 | 2.25e-03 | 4.71e+00 | 9.93e-01 | Female-biased |
| DLBC | ZNF287 | HOXC6 | 3.47e+00 | 3.54e-03 | 4.65e+00 | 9.91e-01 | Female-biased |
| DLBC | ZNF487 | HOXC6 | 3.36e+00 | 5.37e-03 | 4.43e+00 | 9.87e-01 | Female-biased |
| DLBC | ZNF770 | HOXC6 | 2.86e+00 | 2.46e-03 | 4.13e+00 | 9.86e-01 | Female-biased |
| HOXC6 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for HOXC6 |
| RBPs related to ES in HOXC6. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| HOXC6 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs10876243 | chr12:52189418:G:A | - | 0.213950131093098 | 0.000862777161057327 | KIRP | Female-baised eQTL |
| rs17097368 | chr12:46832987:A:G | - | 0.421019991841836 | 0.00821170953971823 | KIRP | Female-baised eQTL |
| rs11170177 | chr12:52572644:G:C | - | 0.193155112724023 | 0.00900633301643206 | KIRP | Female-baised eQTL |
| rs12309844 | chr12:44958551:G:A | - | 0.161956490428245 | 0.0116220032630092 | KIRP | Female-baised eQTL |
| rs12296575 | chr12:44958022:C:T | - | 0.143510274984163 | 0.024748538795564 | KIRP | Female-baised eQTL |
| rs12309630 | chr12:44958177:G:A | - | 0.143510274984163 | 0.024748538795564 | KIRP | Female-baised eQTL |
| rs12305043 | chr12:44958433:T:G | - | 0.143510274984163 | 0.024748538795564 | KIRP | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs112458672 | chr12:52863821:G:A | - | 0.146614117316496 | 0.00100343375001704 | SARC | Male-baised eQTL |
| rs12318750 | chr12:52875544:G:A | - | 0.131392122548951 | 0.0057999991598872 | SARC | Male-baised eQTL |
| rs4919765 | chr12:52876048:G:A | - | 0.131392122548951 | 0.0057999991598872 | SARC | Male-baised eQTL |
| rs7315492 | chr12:52877071:G:A | - | 0.131392122548951 | 0.0057999991598872 | SARC | Male-baised eQTL |
| rs1492238 | chr12:52877996:C:T | - | 0.131392122548951 | 0.0057999991598872 | SARC | Male-baised eQTL |
| rs2682302 | chr12:52880890:G:T | - | 0.131392122548951 | 0.0057999991598872 | SARC | Male-baised eQTL |
| rs2682332 | chr12:52885175:T:C | - | 0.131392122548951 | 0.0057999991598872 | SARC | Male-baised eQTL |
| rs7957691 | chr12:52891023:A:G | - | 0.131392122548951 | 0.0057999991598872 | SARC | Male-baised eQTL |
| rs2172277 | chr12:52892008:C:T | - | 0.131392122548951 | 0.0057999991598872 | SARC | Male-baised eQTL |
| rs7973698 | chr12:52893583:G:A | - | 0.131392122548951 | 0.0057999991598872 | SARC | Male-baised eQTL |
| rs2682316 | chr12:52872813:G:T | - | 0.12415766826458 | 0.00670807274355447 | SARC | Male-baised eQTL |
| rs11171527 | chr12:55513038:C:T | - | 0.0861226603785198 | 0.025740704066177 | KIRC | Male-baised eQTL |
| rs7961849 | chr12:55513662:T:G | - | 0.0861226603785198 | 0.025740704066177 | KIRC | Male-baised eQTL |
| rs10876805 | chr12:55515295:C:T | - | 0.0861226603785198 | 0.025740704066177 | KIRC | Male-baised eQTL |
| rs11171530 | chr12:55516181:C:T | - | 0.0861226603785198 | 0.025740704066177 | KIRC | Male-baised eQTL |
| rs11171531 | chr12:55516370:G:A | - | 0.0861226603785198 | 0.025740704066177 | KIRC | Male-baised eQTL |
| rs4759159 | chr12:55516417:C:T | - | 0.0861226603785198 | 0.025740704066177 | KIRC | Male-baised eQTL |
| rs117161807 | chr12:55518983:T:G | - | 0.0861226603785198 | 0.025740704066177 | KIRC | Male-baised eQTL |
| rs11171533 | chr12:55520152:G:A | - | 0.0861226603785198 | 0.025740704066177 | KIRC | Male-baised eQTL |
| rs11171534 | chr12:55520226:C:A | - | 0.0861226603785198 | 0.025740704066177 | KIRC | Male-baised eQTL |
| rs11171536 | chr12:55521265:A:G | - | 0.0861226603785198 | 0.025740704066177 | KIRC | Male-baised eQTL |
| rs28562727 | chr12:55499541:G:A | - | 0.0773065190025119 | 0.0338250902090181 | KIRC | Male-baised eQTL |
| rs60926711 | chr12:55500632:G:C | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs58586282 | chr12:55500662:G:A | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs57991804 | chr12:55500750:C:T | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs4759156 | chr12:55500858:T:G | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs4759157 | chr12:55500897:T:C | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs4759004 | chr12:55501051:C:A | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs4759158 | chr12:55501330:T:C | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs7304599 | chr12:55501795:A:G | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs7138879 | chr12:55502153:T:C | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs10783752 | chr12:55502266:G:A | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs10876794 | chr12:55502533:A:G | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs11171513 | chr12:55502737:G:A | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs11171514 | chr12:55503100:G:A | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs73341461 | chr12:55503320:T:C | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs10876796 | chr12:55503407:C:T | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs7135420 | chr12:55503768:A:G | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs7960409 | chr12:55504728:A:G | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs10876798 | chr12:55505174:G:T | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs10876800 | chr12:55505506:C:G | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs10876801 | chr12:55505595:C:T | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs10876802 | chr12:55505627:T:C | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs139623454 | chr12:55506864:A:G | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs11520031 | chr12:55507625:T:C | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs11520032 | chr12:55507933:T:C | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs4299522 | chr12:55508269:G:T | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs7397890 | chr12:55508672:T:C | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs10876804 | chr12:55509054:G:C | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs59301794 | chr12:55509664:T:C | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs9738913 | chr12:55509966:A:G | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs9738337 | chr12:55510324:T:C | - | 0.0833024188737679 | 0.0349732983677662 | KIRC | Male-baised eQTL |
| rs10783751 | chr12:55498359:A:T | - | 0.0762520908253605 | 0.036946751239909 | KIRC | Male-baised eQTL |
| rs10876792 | chr12:55499179:C:T | - | 0.0762520908253605 | 0.036946751239909 | KIRC | Male-baised eQTL |
| rs11171507 | chr12:55499883:T:C | - | 0.0762520908253605 | 0.036946751239909 | KIRC | Male-baised eQTL |
| rs10876793 | chr12:55500069:A:G | - | 0.0762520908253605 | 0.036946751239909 | KIRC | Male-baised eQTL |
| rs4759160 | chr12:55516534:A:G | - | 0.0827343147996668 | 0.0376703513581782 | KIRC | Male-baised eQTL |
| rs188513471 | chr12:55521218:T:C | - | 0.0835563299173544 | 0.0393186058597727 | KIRC | Male-baised eQTL |
| rs7304677 | chr12:55515481:T:A | - | 0.0815872929529256 | 0.0436619883782998 | KIRC | Male-baised eQTL |
| rs11615964 | chr12:44867781:C:T | - | 0.0539326791014102 | 0.041501434502092 | BLCA | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000197757 |
| CpG Site: cg16264616 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.428367288861166 | |
 | Gene ID: ENSG00000197757 |
| CpG Site: cg22679316 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.325196923383322 | |
 | Gene ID: ENSG00000197757 |
| CpG Site: cg21837192 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.28147668212919 | |
 | Gene ID: ENSG00000197757 |
| CpG Site: cg09045007 | |
| Position to Gene: gene | |
| Male Effect: -0.0843047390942412 | |
| Female Effect: - | |
 | Gene ID: ENSG00000197757 |
| CpG Site: cg03905819 | |
| Position to Gene: gene,promoter | |
| Male Effect: -0.0892759195666293 | |
| Female Effect: - | |
 | Gene ID: ENSG00000197757 |
| CpG Site: cg15410411 | |
| Position to Gene: gene | |
| Male Effect: -0.0784709303457087 | |
| Female Effect: - | |
 | Gene ID: ENSG00000197757 |
| CpG Site: cg26643142 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.452045340716927 | |
 | Gene ID: ENSG00000197757 |
| CpG Site: cg15772924 | |
| Position to Gene: gene | |
| Male Effect: -0.0699195185649362 | |
| Female Effect: - | |
 | Gene ID: ENSG00000197757 |
| CpG Site: cg27613172 | |
| Position to Gene: gene | |
| Male Effect: -0.327998156019163 | |
| Female Effect: - | |
 | Gene ID: ENSG00000197757 |
| CpG Site: cg13545297 | |
| Position to Gene: gene | |
| Male Effect: -0.422525170828448 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg09045007 | chr12:53998950 | gene | -0.0843047390942412 | 5.50988185363421e-08 | -0.4263508152554699 | 2.7784312704019146e-10 | KIRP |
| cg03905819 | chr12:53991491 | gene,promoter | -0.0892759195666293 | 1.82446191276624e-07 | -0.410401415924495 | 1.4409201837078952e-09 | KIRP |
| cg15410411 | chr12:53999100 | gene | -0.0784709303457087 | 8.85221087624949e-05 | -0.33400857953929747 | 1.2613744413251235e-06 | KIRP |
| cg15772924 | chr12:54019600 | gene | -0.0699195185649362 | 7.67150237039349e-06 | -0.3763115071552813 | 1.5487939537446607e-08 | KIRC |
| cg27613172 | chr12:54007881 | gene | -0.327998156019163 | 5.0047830349694e-06 | -0.3750693382093371 | 1.4897277471538336e-08 | STAD |
| cg13545297 | chr12:54010531 | gene | -0.422525170828448 | 4.80693338840805e-05 | -0.3348533172167474 | 3.657458534383252e-07 | STAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg16264616 | chr12:53997040 | gene | -0.428367288861166 | 9.48617400343271e-12 | -0.508431912955787 | 7.73218806871939e-11 | SARC |
| cg22679316 | chr12:54003206 | gene | -0.325196923383322 | 2.07325894275184e-08 | -0.3852664641021188 | 1.8579815889796192e-06 | SARC |
| cg21837192 | chr12:54004981 | gene | -0.28147668212919 | 1.69889485385096e-06 | -0.4148584315745414 | 2.343196029991467e-07 | SARC |
| cg26643142 | chr12:54005710 | gene | -0.452045340716927 | 2.15759690997855e-16 | -0.8454963761714475 | 5.008052867992443e-21 | KIRP |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of HOXC6 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
