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Gene: ENSG00000196227 |
Summary for FAM217B |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000196227 | Gene symbol | FAM217B |
| Gene name | family with sequence similarity 217 member B | |
| HGNC | 16170 | |
| Entrez ID | 63939 | |
| Gene type | protein_coding | |
| Synonyms | FAM217B|dJ551D2.5 | |
| UniProtAcc | Q9NTX9 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for FAM217B |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for FAM217B |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for FAM217B |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg12181372 | chr20:59933068 | CGI:chr20:59932700-59934462 | promoter | 7.19e-01 | 4.62e-01 | 2.17e+00 | 2.99e-02 | 4.09e-02 | 2.56e-01 |
| LIHC | cg26690949 | chr20:59933888 | CGI:chr20:59932700-59934462 | promoter,gene body | 3.16e-01 | 4.20e-01 | -2.88e+00 | 4.02e-03 | 9.64e-03 | -1.04e-01 |
| GBM | cg26690949 | chr20:59933888 | CGI:chr20:59932700-59934462 | promoter,gene body | 2.26e-02 | 1.28e-01 | -2.26e+00 | 2.36e-02 | 3.81e-02 | -1.05e-01 |
| ESCA | cg20800536 | chr20:59933833 | CGI:chr20:59932700-59934462 | UTR,promoter,exon,gene body | 2.63e-01 | 1.61e-01 | 2.50e+00 | 1.23e-02 | 3.01e-02 | 1.03e-01 |
| ESCA | cg02801359 | chr20:59933867 | CGI:chr20:59932700-59934462 | promoter,gene body | 3.29e-01 | 2.05e-01 | 2.32e+00 | 2.01e-02 | 3.79e-02 | 1.24e-01 |
| ESCA | cg26690949 | chr20:59933888 | CGI:chr20:59932700-59934462 | promoter,gene body | 3.02e-01 | 1.70e-01 | 2.40e+00 | 1.65e-02 | 3.50e-02 | 1.32e-01 |
| ESCA | cg25183989 | chr20:59933531 | CGI:chr20:59932700-59934462 | promoter | 5.78e-01 | 4.58e-01 | 3.06e+00 | 2.22e-03 | 8.93e-03 | 1.20e-01 |
| ESCA | cg00125414 | chr20:59934187 | CGI:chr20:59932700-59934462 | promoter,gene body | 3.06e-01 | 1.76e-01 | 2.84e+00 | 4.47e-03 | 1.55e-02 | 1.30e-01 |
| ESCA | cg14536096 | chr20:59934243 | CGI:chr20:59932700-59934462 | promoter,gene body | 3.03e-01 | 1.81e-01 | 2.12e+00 | 3.41e-02 | 4.54e-02 | 1.22e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUSC | cg26690949 | chr20:59933888 | CGI:chr20:59932700-59934462 | promoter,gene body | 1.22e-01 | 1.67e-02 | 2.86e+00 | 4.19e-03 | 7.14e-03 | 1.05e-01 |
| LUSC | cg06710769 | chr20:59934504 | CGI:chr20:59932700-59934462 | promoter,gene body | 2.33e-01 | 8.49e-02 | 2.25e+00 | 2.44e-02 | 2.79e-02 | 1.48e-01 |
| COAD | cg20800536 | chr20:59933833 | CGI:chr20:59932700-59934462 | UTR,promoter,exon,gene body | 2.80e-01 | 1.09e-01 | 2.59e+00 | 9.47e-03 | 1.38e-02 | 1.72e-01 |
| COAD | cg00125414 | chr20:59934187 | CGI:chr20:59932700-59934462 | promoter,gene body | 2.40e-01 | 6.50e-02 | 3.08e+00 | 2.04e-03 | 4.01e-03 | 1.75e-01 |
| LIHC | cg20800536 | chr20:59933833 | CGI:chr20:59932700-59934462 | UTR,promoter,exon,gene body | 2.60e-01 | 1.19e-01 | 2.45e+00 | 1.41e-02 | 1.65e-02 | 1.42e-01 |
| LIHC | cg06710769 | chr20:59934504 | CGI:chr20:59932700-59934462 | promoter,gene body | 3.85e-01 | 2.08e-01 | 2.84e+00 | 4.56e-03 | 6.08e-03 | 1.77e-01 |
| LIHC | cg14536096 | chr20:59934243 | CGI:chr20:59932700-59934462 | promoter,gene body | 3.41e-01 | 1.74e-01 | 2.90e+00 | 3.68e-03 | 5.03e-03 | 1.67e-01 |
| CHOL | cg12181372 | chr20:59933068 | CGI:chr20:59932700-59934462 | promoter | 8.88e-01 | 6.88e-01 | 2.88e+00 | 4.04e-03 | 1.47e-02 | 2.00e-01 |
| CHOL | cg25183989 | chr20:59933531 | CGI:chr20:59932700-59934462 | promoter | 5.95e-01 | 4.73e-01 | 2.06e+00 | 3.90e-02 | 4.26e-02 | 1.22e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg21950459 | chr20:59933021 | CGI:chr20:59932700-59934462 | promoter | 7.60e-01 | 9.70e-01 | -5.44e+00 | 5.31e-08 | 1.11e-07 | -2.10e-01 |
| BRCA | cg12181372 | chr20:59933068 | CGI:chr20:59932700-59934462 | promoter | 7.19e-01 | 8.67e-01 | -2.59e+00 | 9.47e-03 | 1.07e-02 | -1.48e-01 |
| LIHC | cg25183989 | chr20:59933531 | CGI:chr20:59932700-59934462 | promoter | 5.83e-01 | 4.54e-01 | 3.73e+00 | 1.89e-04 | 6.25e-04 | 1.29e-01 |
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Exon skipping events with PSI in TCGA for FAM217B |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for FAM217B |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for FAM217B |
| TFs related to FAM217B. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| ACC | ZNF235 | FAM217B | 3.99e+00 | 9.86e-01 | 2.85e+00 | 2.33e-03 | Male-biased |
| ACC | ZNF287 | FAM217B | 3.93e+00 | 9.85e-01 | 2.80e+00 | 2.26e-03 | Male-biased |
| BRCA | NKX2-2 | FAM217B | 2.97e+00 | 5.85e-03 | 4.34e+00 | 9.81e-01 | Female-biased |
| BRCA | ZNF235 | FAM217B | 2.22e+00 | 8.12e-04 | 4.22e+00 | 9.83e-01 | Female-biased |
| BRCA | ZNF79 | FAM217B | 1.91e+00 | 1.65e-04 | 4.35e+00 | 9.87e-01 | Female-biased |
| DLBC | ZNF79 | FAM217B | 3.87e+00 | 9.81e-01 | 1.94e+00 | 2.17e-04 | Male-biased |
| GBM | ZNF235 | FAM217B | 3.27e+00 | 9.74e-03 | 4.34e+00 | 9.82e-01 | Female-biased |
| PAAD | NRF1 | FAM217B | 3.13e+00 | 3.38e-03 | 4.14e+00 | 9.86e-01 | Female-biased |
| PAAD | ZNF200 | FAM217B | 3.00e+00 | 2.33e-03 | 4.08e+00 | 9.86e-01 | Female-biased |
| SARC | ZNF235 | FAM217B | 3.98e+00 | 9.83e-01 | 2.89e+00 | 4.69e-04 | Male-biased |
| SARC | ZNF287 | FAM217B | 3.91e+00 | 9.80e-01 | 2.92e+00 | 7.96e-04 | Male-biased |
| FAM217B related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for FAM217B |
| RBPs related to ES in FAM217B. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| FAM217B related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs817684 | chr20:61177706:G:A | - | 0.295235511007252 | 2.29446201435818e-06 | GBM | Female-baised eQTL |
| rs1926076 | chr20:56305721:A:G | - | 0.0490270843683278 | 0.0140640526932782 | LUAD | Female-baised eQTL |
| rs1926075 | chr20:56305761:C:A | - | 0.0490270843683278 | 0.0140640526932782 | LUAD | Female-baised eQTL |
| rs2426612 | chr20:56306924:A:G | - | 0.0490270843683278 | 0.0140640526932782 | LUAD | Female-baised eQTL |
| rs1886956 | chr20:56305340:C:T | - | 0.0489059419952016 | 0.0144504971609553 | LUAD | Female-baised eQTL |
| rs77517711 | chr20:56919083:G:C | - | 0.0508957269091844 | 0.0389512788187112 | LUAD | Female-baised eQTL |
| rs34346006 | chr20:63090574:G:C | - | 0.0424171767932187 | 0.0397049418762104 | LUAD | Female-baised eQTL |
| rs12480795 | chr20:57942157:G:A | - | 0.0353925897367173 | 0.0415166113795554 | LUAD | Female-baised eQTL |
| rs58030696 | chr20:56919745:A:G | - | 0.0500576537459799 | 0.0432922269693795 | LUAD | Female-baised eQTL |
| rs68089336 | chr20:56919804:G:C | - | 0.0500576537459799 | 0.0432922269693795 | LUAD | Female-baised eQTL |
| rs74735349 | chr20:56919908:G:A | - | 0.0500576537459799 | 0.0432922269693795 | LUAD | Female-baised eQTL |
| rs74390820 | chr20:56919961:A:G | - | 0.0500576537459799 | 0.0432922269693795 | LUAD | Female-baised eQTL |
| rs72626591 | chr20:56920091:A:G | - | 0.0500576537459799 | 0.0432922269693795 | LUAD | Female-baised eQTL |
| rs6099346 | chr20:56920986:C:T | - | 0.0500576537459799 | 0.0432922269693795 | LUAD | Female-baised eQTL |
| rs913882 | chr20:57946598:C:T | - | 0.0349162485688387 | 0.0433890927902931 | LUAD | Female-baised eQTL |
| rs884265 | chr20:57946440:T:C | - | 0.034812710758182 | 0.0445847008879917 | LUAD | Female-baised eQTL |
| rs6025914 | chr20:57938772:T:C | - | 0.0350896113032917 | 0.0455112097267084 | LUAD | Female-baised eQTL |
| rs6025915 | chr20:57938804:C:T | - | 0.0350896113032917 | 0.0455112097267084 | LUAD | Female-baised eQTL |
| rs6025916 | chr20:57938812:C:T | - | 0.0350896113032917 | 0.0455112097267084 | LUAD | Female-baised eQTL |
| rs6025917 | chr20:57939010:G:C | - | 0.0350896113032917 | 0.0455112097267084 | LUAD | Female-baised eQTL |
| rs1000122 | chr20:63091056:A:G | - | 0.0383615221762739 | 0.0489559215737947 | LUAD | Female-baised eQTL |
| rs6025924 | chr20:57948284:C:A | - | 0.0343250913032356 | 0.0499703719322533 | LUAD | Female-baised eQTL |
| rs6025926 | chr20:57948587:T:C | - | 0.0343250913032356 | 0.0499703719322533 | LUAD | Female-baised eQTL |
| rs6099331 | chr20:56896327:G:A | - | 0.113596872861254 | 0.00955863229217364 | COAD | Female-baised eQTL |
| rs67773615 | chr20:56895944:C:T | - | 0.108401763083554 | 0.0138042033237749 | COAD | Female-baised eQTL |
| rs17728960 | chr20:51513177:T:C | - | 0.134844355938626 | 0.0330880676408696 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs6999 | chr20:56518845:A:G | - | 0.0570863389327437 | 0.00877834422917511 | BLCA | Male-baised eQTL |
| rs6099183 | chr20:56521172:T:G | - | 0.0570863389327437 | 0.00877834422917511 | BLCA | Male-baised eQTL |
| rs6099184 | chr20:56522422:A:G | - | 0.0565074337151552 | 0.0105377407371993 | BLCA | Male-baised eQTL |
| rs34953792 | chr20:56511225:G:T | - | 0.0563213303764231 | 0.0107789360477076 | BLCA | Male-baised eQTL |
| rs13043526 | chr20:56513742:T:C | - | 0.055668126954546 | 0.0132059203102429 | BLCA | Male-baised eQTL |
| rs6099178 | chr20:56506995:T:C | - | 0.0553532796414129 | 0.0135626142337484 | BLCA | Male-baised eQTL |
| rs11699551 | chr20:56512908:T:C | - | 0.0552228252489856 | 0.0152110448171314 | BLCA | Male-baised eQTL |
| rs6092325 | chr20:56522732:C:T | - | 0.0552228252489856 | 0.0152110448171314 | BLCA | Male-baised eQTL |
| rs13041953 | chr20:56506297:C:T | - | 0.0547536418780613 | 0.0159671007734259 | BLCA | Male-baised eQTL |
| rs11699883 | chr20:56511985:A:C | - | 0.054202330692796 | 0.0160977391641275 | BLCA | Male-baised eQTL |
| rs3787396 | chr20:56503733:T:A | - | 0.0542379805513975 | 0.0165968632647571 | BLCA | Male-baised eQTL |
| rs6069766 | chr20:56503980:A:G | - | 0.0542379805513975 | 0.0165968632647571 | BLCA | Male-baised eQTL |
| rs34983295 | chr20:56504324:G:A | - | 0.0542379805513975 | 0.0165968632647571 | BLCA | Male-baised eQTL |
| rs8123062 | chr20:56494254:T:C | - | 0.0542103003287083 | 0.0167402039519922 | BLCA | Male-baised eQTL |
| rs1884418 | chr20:56495020:G:A | - | 0.0542103003287083 | 0.0167402039519922 | BLCA | Male-baised eQTL |
| rs3827107 | chr20:56495483:G:C | - | 0.0542103003287083 | 0.0167402039519922 | BLCA | Male-baised eQTL |
| rs6064405 | chr20:56495890:C:G | - | 0.0542103003287083 | 0.0167402039519922 | BLCA | Male-baised eQTL |
| rs6099171 | chr20:56496197:A:G | - | 0.0542103003287083 | 0.0167402039519922 | BLCA | Male-baised eQTL |
| rs60654041 | chr20:56502861:C:T | - | 0.0540609994045509 | 0.0169470041378036 | BLCA | Male-baised eQTL |
| rs7265697 | chr20:56495608:C:G | - | 0.0540332038117877 | 0.0170995536869756 | BLCA | Male-baised eQTL |
| rs6069763 | chr20:56496583:A:G | - | 0.0540332038117877 | 0.0170995536869756 | BLCA | Male-baised eQTL |
| rs16979973 | chr20:56481533:A:G | - | 0.0538615516820589 | 0.0177675255035399 | BLCA | Male-baised eQTL |
| rs6064401 | chr20:56482848:G:A | - | 0.0538615516820589 | 0.0177675255035399 | BLCA | Male-baised eQTL |
| rs6064407 | chr20:56500194:A:G | - | 0.0540430061630587 | 0.0178348665836565 | BLCA | Male-baised eQTL |
| rs3787395 | chr20:56503517:G:A | - | 0.053509633492072 | 0.0192910701243396 | BLCA | Male-baised eQTL |
| rs6064406 | chr20:56498771:T:A | - | 0.0510926573402072 | 0.0291917313731271 | BLCA | Male-baised eQTL |
| rs4811694 | chr20:56454332:A:G | - | -0.051279043078288 | 0.0320306748335342 | BLCA | Male-baised eQTL |
| rs401897 | chr20:56454702:T:C | - | -0.0499733979559324 | 0.0416114698839643 | BLCA | Male-baised eQTL |
| rs6101269 | chr20:61222512:G:T | - | 0.116859701005035 | 0.00105936659310336 | COAD | Male-baised eQTL |
| rs62206541 | chr20:53062653:G:A | - | 0.126950023958454 | 0.00152937860124161 | COAD | Male-baised eQTL |
| rs73614382 | chr20:56886977:A:T | - | 0.093241346198649 | 0.00212388971049978 | COAD | Male-baised eQTL |
| rs6093072 | chr20:61223264:C:T | - | 0.118836069044859 | 0.00326399320111119 | COAD | Male-baised eQTL |
| rs6101270 | chr20:61223497:G:A | - | 0.118836069044859 | 0.00326399320111119 | COAD | Male-baised eQTL |
| rs6101271 | chr20:61223634:A:G | - | 0.118836069044859 | 0.00326399320111119 | COAD | Male-baised eQTL |
| rs112556446 | chr20:50018362:G:T | - | 0.124325548972897 | 0.00371206780405243 | COAD | Male-baised eQTL |
| rs78443268 | chr20:50023608:T:C | - | 0.124325548972897 | 0.00371206780405243 | COAD | Male-baised eQTL |
| rs78487338 | chr20:50010840:C:T | - | 0.123099252114305 | 0.00429594585972112 | COAD | Male-baised eQTL |
| rs73309395 | chr20:61204358:T:C | - | 0.120384875214521 | 0.00447233902256161 | COAD | Male-baised eQTL |
| rs7271867 | chr20:61205834:C:T | - | 0.120384875214521 | 0.00447233902256161 | COAD | Male-baised eQTL |
| rs7273563 | chr20:61206236:C:T | - | 0.120384875214521 | 0.00447233902256161 | COAD | Male-baised eQTL |
| rs7273633 | chr20:61206427:A:C | - | 0.120384875214521 | 0.00447233902256161 | COAD | Male-baised eQTL |
| rs73309398 | chr20:61206497:A:G | - | 0.120384875214521 | 0.00447233902256161 | COAD | Male-baised eQTL |
| rs73309401 | chr20:61207408:T:A | - | 0.120384875214521 | 0.00447233902256161 | COAD | Male-baised eQTL |
| rs73309394 | chr20:61203319:G:A | - | 0.121348991587537 | 0.00455812516365827 | COAD | Male-baised eQTL |
| rs4141977 | chr20:49983731:C:T | - | 0.111113222851034 | 0.00458271500903867 | COAD | Male-baised eQTL |
| rs77090490 | chr20:49984863:A:G | - | 0.111113222851034 | 0.00458271500903867 | COAD | Male-baised eQTL |
| rs80012799 | chr20:49976660:T:C | - | 0.110390941891219 | 0.00510610155742899 | COAD | Male-baised eQTL |
| rs113767846 | chr20:49976232:G:C | - | 0.109864575894751 | 0.00550360718850293 | COAD | Male-baised eQTL |
| rs112087360 | chr20:49975583:C:T | - | 0.110129124421047 | 0.00596125976901977 | COAD | Male-baised eQTL |
| rs1995995 | chr20:54806527:T:C | - | 0.0766964460693326 | 0.0065236766528088 | COAD | Male-baised eQTL |
| rs80323694 | chr20:61216113:C:G | - | 0.116928118182632 | 0.00779908099762536 | COAD | Male-baised eQTL |
| rs73311112 | chr20:61216264:T:C | - | 0.116928118182632 | 0.00779908099762536 | COAD | Male-baised eQTL |
| rs74525551 | chr20:61216523:G:C | - | 0.116928118182632 | 0.00779908099762536 | COAD | Male-baised eQTL |
| rs34737810 | chr20:61217589:G:T | - | 0.116928118182632 | 0.00779908099762536 | COAD | Male-baised eQTL |
| rs73311117 | chr20:61217673:G:T | - | 0.116928118182632 | 0.00779908099762536 | COAD | Male-baised eQTL |
| rs6014052 | chr20:54558300:C:T | - | 0.0816701658892058 | 0.00783841648494939 | COAD | Male-baised eQTL |
| rs6101264 | chr20:61213791:G:A | - | 0.116621768772533 | 0.00811328304955427 | COAD | Male-baised eQTL |
| rs74439355 | chr20:61216782:A:G | - | 0.117544078385695 | 0.0082359161156109 | COAD | Male-baised eQTL |
| rs12479884 | chr20:57226729:C:T | - | 0.0873484878587658 | 0.0086338906499582 | COAD | Male-baised eQTL |
| rs1015985 | chr20:57234900:C:T | - | 0.0863093740264942 | 0.00889178000547699 | COAD | Male-baised eQTL |
| rs4810061 | chr20:57226596:G:C | - | 0.0879422459138619 | 0.00896350560302707 | COAD | Male-baised eQTL |
| rs11697021 | chr20:57227016:G:A | - | 0.0868397705829414 | 0.0092004611585105 | COAD | Male-baised eQTL |
| rs162313 | chr20:57229121:G:A | - | 0.0868397705829414 | 0.0092004611585105 | COAD | Male-baised eQTL |
| rs2426702 | chr20:57230370:C:T | - | 0.0868397705829414 | 0.0092004611585105 | COAD | Male-baised eQTL |
| rs6101274 | chr20:61228784:C:A | - | 0.114344666855653 | 0.00956546725835877 | COAD | Male-baised eQTL |
| rs6127975 | chr20:57236244:G:A | - | 0.0831987418145637 | 0.0116695425086144 | COAD | Male-baised eQTL |
| rs78704833 | chr20:61278537:T:C | - | 0.109027141509816 | 0.0141836981917565 | COAD | Male-baised eQTL |
| rs4811611 | chr20:55674437:T:A | - | 0.0685109322295978 | 0.0176007717040072 | COAD | Male-baised eQTL |
| rs78553081 | chr20:57254314:C:T | - | 0.0870372725804298 | 0.0195662614790787 | COAD | Male-baised eQTL |
| rs112773109 | chr20:57251751:T:A | - | 0.0851416488770599 | 0.0199489544968384 | COAD | Male-baised eQTL |
| rs6123684 | chr20:57252029:A:C | - | 0.0851416488770599 | 0.0199489544968384 | COAD | Male-baised eQTL |
| rs6127981 | chr20:57249093:G:T | - | 0.0836626977802651 | 0.0222531153051367 | COAD | Male-baised eQTL |
| rs6127982 | chr20:57249311:T:C | - | 0.0836626977802651 | 0.0222531153051367 | COAD | Male-baised eQTL |
| rs6127980 | chr20:57248706:G:A | - | 0.0828987037266405 | 0.0249151397297409 | COAD | Male-baised eQTL |
| rs58003327 | chr20:56887036:A:G | - | 0.0711468315896099 | 0.0267146181845719 | COAD | Male-baised eQTL |
| rs6023362 | chr20:54560297:C:T | - | 0.0712121546765793 | 0.0275150774976593 | COAD | Male-baised eQTL |
| rs1970545 | chr20:61235219:C:A | - | -0.0913197809875466 | 0.0289775312404049 | COAD | Male-baised eQTL |
| rs1000122 | chr20:63091056:A:G | - | 0.0775759649275898 | 0.0319263337806225 | COAD | Male-baised eQTL |
| rs6097012 | chr20:52529934:T:C | - | 0.0603893116987409 | 0.0322695080922347 | COAD | Male-baised eQTL |
| rs1160398 | chr20:55671458:G:A | - | 0.062806987004532 | 0.0340094219782687 | COAD | Male-baised eQTL |
| rs4812174 | chr20:60458069:C:T | - | 0.0544779261034551 | 0.0347295921846619 | COAD | Male-baised eQTL |
| rs6097957 | chr20:54398021:C:A | - | 0.0807909498948955 | 0.0350834037524866 | COAD | Male-baised eQTL |
| rs6067388 | chr20:50264730:G:A | - | 0.0780210329830987 | 0.0374824683787554 | COAD | Male-baised eQTL |
| rs73917909 | chr20:57293029:C:T | - | 0.0667082835089854 | 0.043618682948147 | COAD | Male-baised eQTL |
| rs7353605 | chr20:51150601:G:A | - | 0.069761523972463 | 0.044147351154728 | COAD | Male-baised eQTL |
| rs6063605 | chr20:51150959:A:G | - | 0.069761523972463 | 0.044147351154728 | COAD | Male-baised eQTL |
| rs2904087 | chr20:51152258:A:G | - | 0.069761523972463 | 0.044147351154728 | COAD | Male-baised eQTL |
| rs2426700 | chr20:57227232:T:C | - | 0.0720332619869743 | 0.0441517964412349 | COAD | Male-baised eQTL |
| rs6070343 | chr20:58073850:G:A | - | 0.0807652736047102 | 0.0446382653685829 | COAD | Male-baised eQTL |
| rs78445860 | chr20:51148003:T:C | - | 0.0692283438318175 | 0.0465264510901707 | COAD | Male-baised eQTL |
| rs6068445 | chr20:53058868:G:A | - | 0.051888697909705 | 0.0491109125435016 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000196227 |
| CpG Site: cg12181372 | |
| Position to Gene: promoter | |
| Male Effect: - | |
| Female Effect: -0.45407543990513 | |
 | Gene ID: ENSG00000196227 |
| CpG Site: cg01248445 | |
| Position to Gene: gene,enhancer | |
| Male Effect: - | |
| Female Effect: -0.164613334084673 | |
 | Gene ID: ENSG00000196227 |
| CpG Site: cg01248445 | |
| Position to Gene: gene,enhancer | |
| Male Effect: -0.118509105301274 | |
| Female Effect: - | |
 | Gene ID: ENSG00000196227 |
| CpG Site: cg02434703 | |
| Position to Gene: gene,exon,CDS | |
| Male Effect: -0.374828429532693 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg01248445 | chr20:59938454 | gene,enhancer | -0.118509105301274 | 4.53297989961236e-10 | -0.4095986485981351 | 1.5022289092584132e-12 | LUSC |
| cg02434703 | chr20:59944115 | gene,exon,CDS | -0.374828429532693 | 2.88568440210324e-06 | -0.3494755662579381 | 2.920445208491376e-09 | LUSC |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg12181372 | chr20:59933068 | promoter | -0.45407543990513 | 2.3804734727156e-21 | -0.5820979002227118 | 1.587239443072095e-24 | LUAD |
| cg01248445 | chr20:59938454 | gene,enhancer | -0.164613334084673 | 5.35781808191668e-07 | -0.3717868328886247 | 8.849414584191777e-10 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of FAM217B |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
