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Gene: ENSG00000188997 |
Summary for KCTD21 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000188997 | Gene symbol | KCTD21 |
| Gene name | potassium channel tetramerization domain containing 21 | |
| HGNC | 27452 | |
| Entrez ID | 283219 | |
| Gene type | protein_coding | |
| Synonyms | KCTD21|KCASH2 | |
| UniProtAcc | Q4G0X4 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for KCTD21 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| KCTD21 | 5.56e+02 | -1.49e+00 | 3.12e-01 | -4.76e+00 | 1.92e-06 | 1.30e-05 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for KCTD21 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for KCTD21 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| CHOL | cg00808969 | chr11:78187739 | CGI:chr11:78188518-78188944 | promoter,gene body | 4.28e-01 | 3.03e-01 | 2.61e+00 | 9.04e-03 | 2.00e-02 | 1.24e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| THCA | cg00808969 | chr11:78187739 | CGI:chr11:78188518-78188944 | promoter,gene body | 1.84e-01 | 2.89e-01 | -5.16e+00 | 2.42e-07 | 1.27e-05 | -1.05e-01 |
| CHOL | cg00808969 | chr11:78187739 | CGI:chr11:78188518-78188944 | promoter,gene body | 3.03e-01 | 1.82e-01 | 2.36e+00 | 1.83e-02 | 2.92e-02 | 1.22e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUAD | cg00808969 | chr11:78187739 | CGI:chr11:78188518-78188944 | promoter,gene body | 3.60e-01 | 2.30e-01 | 3.39e+00 | 6.97e-04 | 2.53e-03 | 1.30e-01 |
| BLCA | cg00808969 | chr11:78187739 | CGI:chr11:78188518-78188944 | promoter,gene body | 4.05e-01 | 2.91e-01 | 2.78e+00 | 5.51e-03 | 1.21e-02 | 1.13e-01 |
Top |
Exon skipping events with PSI in TCGA for KCTD21 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for KCTD21 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for KCTD21 |
| TFs related to KCTD21. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| KCTD21 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for KCTD21 |
| RBPs related to ES in KCTD21. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| KCTD21 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs11607979 | chr11:68356817:G:A | - | 0.18774416911197 | 0.0165512866871237 | HNSC | Female-baised eQTL |
| rs7126711 | chr11:69091909:A:G | - | -0.153680358197749 | 0.00620487097361151 | BLCA | Female-baised eQTL |
| rs4930261 | chr11:69077498:G:A | - | -0.153504303735103 | 0.00642185403612742 | BLCA | Female-baised eQTL |
| rs4608106 | chr11:71117422:C:G | - | 0.150583115441761 | 0.00894783648665948 | BLCA | Female-baised eQTL |
| rs618076 | chr11:76885460:G:T | - | 0.18806315087337 | 0.00969520070052692 | BLCA | Female-baised eQTL |
| rs12273080 | chr11:69085565:T:G | - | -0.11496064656968 | 0.0118204198753162 | BLCA | Female-baised eQTL |
| rs7930211 | chr11:69060249:T:C | - | -0.14280814256117 | 0.0138844679566015 | BLCA | Female-baised eQTL |
| rs34963582 | chr11:86768579:G:A | - | 0.13702179110697 | 0.0178248067366394 | BLCA | Female-baised eQTL |
| rs10896414 | chr11:69069797:C:T | - | -0.120494005766757 | 0.0201839797797297 | BLCA | Female-baised eQTL |
| rs1551310 | chr11:69089570:C:T | - | -0.12001877788602 | 0.0208943967929181 | BLCA | Female-baised eQTL |
| rs4930650 | chr11:69090796:A:G | - | -0.12001877788602 | 0.0208943967929181 | BLCA | Female-baised eQTL |
| rs10896412 | chr11:69069784:C:G | - | -0.119199513578986 | 0.0241075630584137 | BLCA | Female-baised eQTL |
| rs7102709 | chr11:69074103:A:G | - | -0.114063004913247 | 0.0334348783406992 | BLCA | Female-baised eQTL |
| rs6591371 | chr11:69076445:C:G | - | -0.114063004913247 | 0.0334348783406992 | BLCA | Female-baised eQTL |
| rs4930262 | chr11:69077974:A:G | - | -0.114063004913247 | 0.0334348783406992 | BLCA | Female-baised eQTL |
| rs4930649 | chr11:69078630:A:G | - | -0.114063004913247 | 0.0334348783406992 | BLCA | Female-baised eQTL |
| rs12804893 | chr11:69079670:T:C | - | -0.114063004913247 | 0.0334348783406992 | BLCA | Female-baised eQTL |
| rs3794019 | chr11:69081144:A:G | - | -0.114063004913247 | 0.0334348783406992 | BLCA | Female-baised eQTL |
| rs7944256 | chr11:69081874:T:C | - | -0.114063004913247 | 0.0334348783406992 | BLCA | Female-baised eQTL |
| rs2376558 | chr11:69083946:T:C | - | -0.114063004913247 | 0.0334348783406992 | BLCA | Female-baised eQTL |
| rs930786 | chr11:69093166:T:C | - | -0.114063004913247 | 0.0334348783406992 | BLCA | Female-baised eQTL |
| rs72969403 | chr11:86795472:T:C | - | 0.111621913484408 | 0.0361828356386895 | BLCA | Female-baised eQTL |
| rs72967500 | chr11:86794078:C:T | - | 0.110915770451554 | 0.0387689411420361 | BLCA | Female-baised eQTL |
| rs72969405 | chr11:86795501:G:A | - | 0.110915770451554 | 0.0387689411420361 | BLCA | Female-baised eQTL |
| rs11605575 | chr11:86797052:C:A | - | 0.110569347986776 | 0.0406515372114829 | BLCA | Female-baised eQTL |
| rs72969407 | chr11:86797372:C:T | - | 0.110569347986776 | 0.0406515372114829 | BLCA | Female-baised eQTL |
| rs72969411 | chr11:86797740:A:G | - | 0.110569347986776 | 0.0406515372114829 | BLCA | Female-baised eQTL |
| rs72969419 | chr11:86798321:C:A | - | 0.110569347986776 | 0.0406515372114829 | BLCA | Female-baised eQTL |
| rs72969422 | chr11:86799581:C:T | - | 0.110569347986776 | 0.0406515372114829 | BLCA | Female-baised eQTL |
| rs12224755 | chr11:80373221:G:C | - | 0.117320243154857 | 0.0462155937265186 | BLCA | Female-baised eQTL |
| rs200415548 | chr11:85744993:C:T | - | 0.0744583127838241 | 0.000554334670488381 | LUAD | Female-baised eQTL |
| rs11234390 | chr11:85723517:T:C | - | 0.0839044117342815 | 0.000597528823343526 | LUAD | Female-baised eQTL |
| rs11234391 | chr11:85723748:A:G | - | 0.0839044117342815 | 0.000597528823343526 | LUAD | Female-baised eQTL |
| rs12365370 | chr11:85788940:T:C | - | 0.0790903274273924 | 0.000666165080437119 | LUAD | Female-baised eQTL |
| rs11234413 | chr11:85795951:G:A | - | 0.0784999524786611 | 0.000770985471090495 | LUAD | Female-baised eQTL |
| rs11234415 | chr11:85802192:C:T | - | 0.0784999524786611 | 0.000770985471090495 | LUAD | Female-baised eQTL |
| rs11234397 | chr11:85745199:C:T | - | 0.0712356634135722 | 0.00116522335187421 | LUAD | Female-baised eQTL |
| rs117964475 | chr11:85778482:G:T | - | 0.0775662254462929 | 0.0012625720757438 | LUAD | Female-baised eQTL |
| rs11234392 | chr11:85732179:T:A | - | 0.0765564766631483 | 0.00129908514385193 | LUAD | Female-baised eQTL |
| rs11234393 | chr11:85733165:C:T | - | 0.0765564766631483 | 0.00129908514385193 | LUAD | Female-baised eQTL |
| rs190635972 | chr11:85733669:G:A | - | 0.0765564766631483 | 0.00129908514385193 | LUAD | Female-baised eQTL |
| rs11234395 | chr11:85735080:C:G | - | 0.0765564766631483 | 0.00129908514385193 | LUAD | Female-baised eQTL |
| rs2304343 | chr11:85745806:T:A | - | 0.0762313487083961 | 0.00140794090557882 | LUAD | Female-baised eQTL |
| rs11234404 | chr11:85769994:G:A | - | 0.0734528003158044 | 0.00231697125282934 | LUAD | Female-baised eQTL |
| rs77171870 | chr11:85770393:C:T | - | 0.0734528003158044 | 0.00231697125282934 | LUAD | Female-baised eQTL |
| rs75918023 | chr11:85776864:T:A | - | 0.0734528003158044 | 0.00231697125282934 | LUAD | Female-baised eQTL |
| rs17811120 | chr11:85766240:G:T | - | 0.0730829550460106 | 0.0025308530852078 | LUAD | Female-baised eQTL |
| rs76495121 | chr11:85765016:T:G | - | 0.066267553015535 | 0.0032320838036225 | LUAD | Female-baised eQTL |
| rs11234386 | chr11:85709042:G:A | - | 0.0725405369238031 | 0.00326941946511681 | LUAD | Female-baised eQTL |
| rs11234387 | chr11:85709133:C:T | - | 0.0713648053051126 | 0.00360961827142495 | LUAD | Female-baised eQTL |
| rs11234408 | chr11:85785199:C:T | - | 0.0622124427655861 | 0.00619061595110054 | LUAD | Female-baised eQTL |
| rs79363624 | chr11:85778768:C:T | - | 0.0618576577042344 | 0.00672195707849808 | LUAD | Female-baised eQTL |
| rs11234409 | chr11:85785365:G:A | - | 0.0618576577042344 | 0.00672195707849808 | LUAD | Female-baised eQTL |
| rs79338073 | chr11:85763123:A:T | - | 0.059428010958201 | 0.00950100015154642 | LUAD | Female-baised eQTL |
| rs11234406 | chr11:85771914:A:T | - | 0.059428010958201 | 0.00950100015154642 | LUAD | Female-baised eQTL |
| rs3891432 | chr11:85769121:A:G | - | 0.0593621788710132 | 0.00968045441230504 | LUAD | Female-baised eQTL |
| rs10501597 | chr11:85770648:G:A | - | 0.059069401654692 | 0.010304887932225 | LUAD | Female-baised eQTL |
| rs11234427 | chr11:85825952:T:C | - | 0.0622397405407394 | 0.0108575407564222 | LUAD | Female-baised eQTL |
| rs11234416 | chr11:85803650:A:G | - | 0.0651963145882837 | 0.013747797621301 | LUAD | Female-baised eQTL |
| rs77329233 | chr11:85821507:C:T | - | 0.065845193820322 | 0.0161485825883189 | LUAD | Female-baised eQTL |
| rs10898409 | chr11:85793870:T:C | - | 0.0478069773122832 | 0.0179418098510812 | LUAD | Female-baised eQTL |
| rs12286030 | chr11:85805155:G:A | - | 0.0557359225997762 | 0.0179598745661953 | LUAD | Female-baised eQTL |
| rs17209127 | chr11:85821654:G:A | - | 0.0618411787189529 | 0.0212095558909243 | LUAD | Female-baised eQTL |
| rs2276018 | chr11:85695384:G:T | - | 0.0586675553517067 | 0.0271338114154127 | LUAD | Female-baised eQTL |
| rs12286206 | chr11:85805513:G:C | - | 0.0519074248055829 | 0.0339816567897125 | LUAD | Female-baised eQTL |
| rs10898803 | chr11:87933866:T:A | - | 0.0564969234008429 | 0.0346688628273165 | LUAD | Female-baised eQTL |
| rs201622451 | chr11:86536472:G:A | - | 0.052522053385413 | 0.044147625461156 | LUAD | Female-baised eQTL |
| rs12286043 | chr11:85805213:G:A | - | 0.0480593568951907 | 0.0485816582990934 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs73511164 | chr11:84622850:G:A | - | -0.134255776878242 | 0.0468561337871721 | THCA | Male-baised eQTL |
| rs972139 | chr11:79052710:T:C | - | -0.163300384803957 | 0.0256061748470432 | SARC | Male-baised eQTL |
| rs7124972 | chr11:81291756:C:T | - | 0.0623460995715646 | 0.0154472437987982 | STAD | Male-baised eQTL |
| rs11237730 | chr11:79146393:C:T | - | 0.0593913473257265 | 0.0222432134999549 | STAD | Male-baised eQTL |
| rs10501583 | chr11:84971397:T:A | - | 0.0581526026592744 | 0.000993852747743447 | BLCA | Male-baised eQTL |
| rs141259330 | chr11:83941549:T:C | - | 0.0464481336387358 | 0.00166049750708902 | BLCA | Male-baised eQTL |
| rs12292654 | chr11:83939781:A:G | - | 0.0462411086044716 | 0.00183829548592713 | BLCA | Male-baised eQTL |
| rs11233828 | chr11:83942494:A:G | - | 0.0456301583029176 | 0.00202388727995403 | BLCA | Male-baised eQTL |
| rs11233829 | chr11:83942509:G:T | - | 0.0456301583029176 | 0.00202388727995403 | BLCA | Male-baised eQTL |
| rs12273905 | chr11:83936733:C:T | - | 0.0454885227642496 | 0.00216318459803301 | BLCA | Male-baised eQTL |
| rs12284526 | chr11:83938481:T:C | - | 0.0454885227642496 | 0.00216318459803301 | BLCA | Male-baised eQTL |
| rs12284566 | chr11:83938528:T:C | - | 0.0454885227642496 | 0.00216318459803301 | BLCA | Male-baised eQTL |
| rs74740858 | chr11:83939280:G:A | - | 0.0454885227642496 | 0.00216318459803301 | BLCA | Male-baised eQTL |
| rs12279346 | chr11:83939305:G:T | - | 0.0454885227642496 | 0.00216318459803301 | BLCA | Male-baised eQTL |
| rs76769274 | chr11:83940147:A:G | - | 0.0454885227642496 | 0.00216318459803301 | BLCA | Male-baised eQTL |
| rs12271521 | chr11:83940658:G:T | - | 0.0454885227642496 | 0.00216318459803301 | BLCA | Male-baised eQTL |
| rs12271485 | chr11:83940730:C:G | - | 0.0454885227642496 | 0.00216318459803301 | BLCA | Male-baised eQTL |
| rs117770242 | chr11:83941416:G:A | - | 0.0454885227642496 | 0.00216318459803301 | BLCA | Male-baised eQTL |
| rs76299377 | chr11:83941769:C:A | - | 0.0454885227642496 | 0.00216318459803301 | BLCA | Male-baised eQTL |
| rs11233826 | chr11:83942397:C:T | - | 0.0454885227642496 | 0.00216318459803301 | BLCA | Male-baised eQTL |
| rs6592224 | chr11:84954620:G:T | - | 0.0513465289721351 | 0.00248410412295831 | BLCA | Male-baised eQTL |
| rs79490358 | chr11:87512886:T:C | - | 0.0480090976961727 | 0.00395955304690446 | BLCA | Male-baised eQTL |
| rs72945801 | chr11:83913069:T:C | - | 0.0406391848409335 | 0.0055049653295977 | BLCA | Male-baised eQTL |
| rs12293121 | chr11:83918197:T:G | - | 0.0406391848409335 | 0.0055049653295977 | BLCA | Male-baised eQTL |
| rs72947723 | chr11:83918996:A:G | - | 0.0406391848409335 | 0.0055049653295977 | BLCA | Male-baised eQTL |
| rs12271245 | chr11:83917556:A:T | - | 0.0403491884428325 | 0.00568547033500507 | BLCA | Male-baised eQTL |
| rs34520201 | chr11:83762060:C:A | - | 0.0525769233339201 | 0.00582781883315148 | BLCA | Male-baised eQTL |
| rs12285920 | chr11:83923768:C:T | - | 0.0405237033343019 | 0.00582830886856144 | BLCA | Male-baised eQTL |
| rs11233811 | chr11:83924058:C:T | - | 0.0405237033343019 | 0.00582830886856144 | BLCA | Male-baised eQTL |
| rs12287742 | chr11:83924630:C:T | - | 0.0405237033343019 | 0.00582830886856144 | BLCA | Male-baised eQTL |
| rs35047639 | chr11:83762248:C:T | - | 0.0524784002583237 | 0.00598942923734313 | BLCA | Male-baised eQTL |
| rs12285761 | chr11:83923452:C:T | - | 0.0403537487247584 | 0.00627251722333896 | BLCA | Male-baised eQTL |
| rs12800326 | chr11:83753820:A:G | - | 0.0504410880964941 | 0.00899894548989496 | BLCA | Male-baised eQTL |
| rs188476701 | chr11:83753862:A:G | - | 0.0504410880964941 | 0.00899894548989496 | BLCA | Male-baised eQTL |
| rs4456272 | chr11:83758487:C:T | - | 0.0504410880964941 | 0.00899894548989496 | BLCA | Male-baised eQTL |
| rs71465559 | chr11:83758721:A:T | - | 0.0504410880964941 | 0.00899894548989496 | BLCA | Male-baised eQTL |
| rs12277425 | chr11:83899067:T:C | - | 0.036424585060704 | 0.0112666090285615 | BLCA | Male-baised eQTL |
| rs35301519 | chr11:83725563:G:T | - | 0.048839387712085 | 0.011789417817892 | BLCA | Male-baised eQTL |
| rs17481934 | chr11:83725836:C:T | - | 0.048839387712085 | 0.011789417817892 | BLCA | Male-baised eQTL |
| rs36110284 | chr11:83740710:T:C | - | 0.0487331693372306 | 0.0121448452554581 | BLCA | Male-baised eQTL |
| rs12792825 | chr11:83743835:G:A | - | 0.0487336442017796 | 0.0121732774890528 | BLCA | Male-baised eQTL |
| rs12786565 | chr11:83749816:T:C | - | 0.0486831476455187 | 0.0123363433027997 | BLCA | Male-baised eQTL |
| rs71465556 | chr11:83750323:T:C | - | 0.0486831476455187 | 0.0123363433027997 | BLCA | Male-baised eQTL |
| rs12788595 | chr11:83746681:C:A | - | 0.0486600067071752 | 0.0124159618871254 | BLCA | Male-baised eQTL |
| rs71465557 | chr11:83751067:A:C | - | 0.0486341379016753 | 0.0125341117873634 | BLCA | Male-baised eQTL |
| rs34873133 | chr11:83751202:T:C | - | 0.0486341379016753 | 0.0125341117873634 | BLCA | Male-baised eQTL |
| rs35627230 | chr11:83748923:G:A | - | 0.0486187397055595 | 0.0126454156513382 | BLCA | Male-baised eQTL |
| rs12290784 | chr11:83901363:C:T | - | 0.0357673476856279 | 0.0134182996543511 | BLCA | Male-baised eQTL |
| rs71465553 | chr11:83706736:C:T | - | 0.0474569906790063 | 0.0146299268537162 | BLCA | Male-baised eQTL |
| rs12787861 | chr11:83707769:C:T | - | 0.0474569906790063 | 0.0146299268537162 | BLCA | Male-baised eQTL |
| rs11233724 | chr11:83709270:T:G | - | 0.0474569906790063 | 0.0146299268537162 | BLCA | Male-baised eQTL |
| rs36125731 | chr11:83712904:C:T | - | 0.0474569906790063 | 0.0146299268537162 | BLCA | Male-baised eQTL |
| rs34514322 | chr11:83713614:A:G | - | 0.0474569906790063 | 0.0146299268537162 | BLCA | Male-baised eQTL |
| rs34994208 | chr11:83713782:T:C | - | 0.0474569906790063 | 0.0146299268537162 | BLCA | Male-baised eQTL |
| rs35954003 | chr11:83716100:A:C | - | 0.0474569906790063 | 0.0146299268537162 | BLCA | Male-baised eQTL |
| rs118106162 | chr11:83716506:C:T | - | 0.0474569906790063 | 0.0146299268537162 | BLCA | Male-baised eQTL |
| rs117792962 | chr11:83716543:G:A | - | 0.0474569906790063 | 0.0146299268537162 | BLCA | Male-baised eQTL |
| rs71465554 | chr11:83718688:G:A | - | 0.0474569906790063 | 0.0146299268537162 | BLCA | Male-baised eQTL |
| rs116872257 | chr11:83719005:G:A | - | 0.0474569906790063 | 0.0146299268537162 | BLCA | Male-baised eQTL |
| rs12806068 | chr11:83694153:A:G | - | 0.0474423454310309 | 0.0147235034676229 | BLCA | Male-baised eQTL |
| rs139808696 | chr11:83699566:C:T | - | 0.0474423454310309 | 0.0147235034676229 | BLCA | Male-baised eQTL |
| rs1892949 | chr11:83701979:A:G | - | 0.0474423454310309 | 0.0147235034676229 | BLCA | Male-baised eQTL |
| rs12281733 | chr11:83898219:A:T | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12295183 | chr11:83898370:G:A | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs61901785 | chr11:83898505:T:G | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs61901786 | chr11:83898522:C:T | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12276012 | chr11:83898892:T:C | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12276017 | chr11:83898908:T:C | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12277476 | chr11:83899177:T:C | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12270625 | chr11:83899274:G:A | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12277615 | chr11:83899420:T:C | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12270635 | chr11:83899443:C:G | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs116582965 | chr11:83899693:G:A | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12289010 | chr11:83900365:G:A | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12295931 | chr11:83900370:T:C | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12289288 | chr11:83900804:G:A | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12271229 | chr11:83901050:T:C | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12271288 | chr11:83901148:T:C | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs66866105 | chr11:83901717:C:T | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs61901788 | chr11:83901992:A:T | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs61901789 | chr11:83902008:C:A | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12279274 | chr11:83902087:A:G | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs7111282 | chr11:83902491:A:T | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12279522 | chr11:83902526:A:C | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs7111645 | chr11:83902723:C:T | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12281299 | chr11:83903349:A:G | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12294501 | chr11:83903351:C:G | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12275181 | chr11:83903470:T:C | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12275182 | chr11:83903471:T:G | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12281403 | chr11:83903582:A:G | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12294813 | chr11:83903901:C:T | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12276898 | chr11:83904078:T:G | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs11233799 | chr11:83905161:T:C | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12271843 | chr11:83905188:G:T | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12273731 | chr11:83906226:G:T | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12286857 | chr11:83906349:A:G | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12286986 | chr11:83906529:A:G | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs12273942 | chr11:83906610:G:A | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs61901822 | chr11:83906897:T:G | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs61901823 | chr11:83907044:A:G | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs61901824 | chr11:83907673:A:C | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs7105997 | chr11:83907973:C:T | - | 0.0351643075668543 | 0.0156697443778141 | BLCA | Male-baised eQTL |
| rs73513704 | chr11:84056068:T:C | - | 0.0444910694829357 | 0.0160877144201297 | BLCA | Male-baised eQTL |
| rs12791719 | chr11:83664137:A:T | - | 0.0455275602403242 | 0.0187786279002909 | BLCA | Male-baised eQTL |
| rs35589467 | chr11:83668700:T:C | - | 0.046011248198691 | 0.018913355480044 | BLCA | Male-baised eQTL |
| rs72943850 | chr11:83901887:T:A | - | 0.0348044348926222 | 0.0190650079165382 | BLCA | Male-baised eQTL |
| rs977822 | chr11:83665972:C:A | - | 0.0459553359420972 | 0.0191151632235535 | BLCA | Male-baised eQTL |
| rs34718216 | chr11:83669431:G:A | - | 0.0459553359420972 | 0.0191151632235535 | BLCA | Male-baised eQTL |
| rs76751610 | chr11:83676695:C:T | - | 0.0459553359420972 | 0.0191151632235535 | BLCA | Male-baised eQTL |
| rs34839973 | chr11:83678534:C:A | - | 0.0459551240577909 | 0.0192466094462616 | BLCA | Male-baised eQTL |
| rs12803579 | chr11:83678504:A:T | - | 0.0458994192400496 | 0.0194393225006985 | BLCA | Male-baised eQTL |
| rs34843650 | chr11:83688988:C:T | - | 0.0458994192400496 | 0.0194393225006985 | BLCA | Male-baised eQTL |
| rs71465552 | chr11:83689907:T:C | - | 0.0458994192400496 | 0.0194393225006985 | BLCA | Male-baised eQTL |
| rs11233798 | chr11:83905143:C:T | - | 0.0342863311415334 | 0.0202268711983822 | BLCA | Male-baised eQTL |
| rs12280579 | chr11:83906104:T:C | - | 0.0333450963924215 | 0.0235075873252514 | BLCA | Male-baised eQTL |
| rs12275162 | chr11:83942671:C:T | - | 0.039965641504665 | 0.0262457778248538 | BLCA | Male-baised eQTL |
| rs12288437 | chr11:83942859:A:C | - | 0.039965641504665 | 0.0262457778248538 | BLCA | Male-baised eQTL |
| rs1471685 | chr11:83943748:C:T | - | 0.0392145788907077 | 0.0322590202619727 | BLCA | Male-baised eQTL |
| rs1471686 | chr11:83943920:C:T | - | 0.0392145788907077 | 0.0322590202619727 | BLCA | Male-baised eQTL |
| rs12285562 | chr11:83944039:T:C | - | 0.0392145788907077 | 0.0322590202619727 | BLCA | Male-baised eQTL |
| rs12278816 | chr11:83944309:G:A | - | 0.0392145788907077 | 0.0322590202619727 | BLCA | Male-baised eQTL |
| rs341081 | chr11:72544800:T:C | - | 0.0397556978049405 | 0.0325758606621379 | BLCA | Male-baised eQTL |
| rs11233853 | chr11:83954490:G:T | - | 0.0377839337270169 | 0.0339458380796499 | BLCA | Male-baised eQTL |
| rs75469544 | chr11:83961366:A:G | - | 0.0374172860530169 | 0.0348085256618492 | BLCA | Male-baised eQTL |
| rs77729597 | chr11:83961631:G:C | - | 0.0374172860530169 | 0.0348085256618492 | BLCA | Male-baised eQTL |
| rs11233805 | chr11:83912032:A:C | - | 0.0315257526313372 | 0.0353208628078493 | BLCA | Male-baised eQTL |
| rs1384754 | chr11:83944565:G:A | - | 0.0387747886067689 | 0.0360044518413025 | BLCA | Male-baised eQTL |
| rs1384755 | chr11:83944851:G:A | - | 0.0387747886067689 | 0.0360044518413025 | BLCA | Male-baised eQTL |
| rs11233833 | chr11:83945191:G:A | - | 0.0387747886067689 | 0.0360044518413025 | BLCA | Male-baised eQTL |
| rs11233834 | chr11:83945241:G:A | - | 0.0387747886067689 | 0.0360044518413025 | BLCA | Male-baised eQTL |
| rs11233835 | chr11:83945245:C:A | - | 0.0387747886067689 | 0.0360044518413025 | BLCA | Male-baised eQTL |
| rs77559735 | chr11:83945526:A:T | - | 0.0387747886067689 | 0.0360044518413025 | BLCA | Male-baised eQTL |
| rs12288941 | chr11:83921335:T:C | - | 0.0314073931517882 | 0.0371064982310813 | BLCA | Male-baised eQTL |
| rs4943994 | chr11:87718530:T:A | - | -0.0366144396297371 | 0.0381229828626598 | BLCA | Male-baised eQTL |
| rs649957 | chr11:78915360:C:T | - | 0.0243578393444125 | 0.0401460320894137 | BLCA | Male-baised eQTL |
| rs142530135 | chr11:83946130:C:T | - | 0.038183381840627 | 0.0419526303992807 | BLCA | Male-baised eQTL |
| rs188597705 | chr11:83946131:A:G | - | 0.038183381840627 | 0.0419526303992807 | BLCA | Male-baised eQTL |
| rs180700333 | chr11:83946132:A:G | - | 0.038183381840627 | 0.0419526303992807 | BLCA | Male-baised eQTL |
| rs61900045 | chr11:83869254:C:T | - | 0.0333572794905445 | 0.0424251586251987 | BLCA | Male-baised eQTL |
| rs3844141 | chr11:84977018:T:C | - | 0.0297289935740826 | 0.0445688207009201 | BLCA | Male-baised eQTL |
| rs4084193 | chr11:82840516:T:G | - | 0.0245860627606225 | 0.0484892349924527 | BLCA | Male-baised eQTL |
| rs11605184 | chr11:70885792:G:A | - | 0.0696412372825789 | 0.0234149147939532 | LUAD | Male-baised eQTL |
| rs12274873 | chr11:78471969:C:G | - | 0.0455806608177021 | 0.0433381083967288 | LUAD | Male-baised eQTL |
| rs10501455 | chr11:79801985:G:A | - | -0.0610872903381421 | 0.00916657212754048 | COAD | Male-baised eQTL |
| rs1391533 | chr11:80958903:T:C | - | -0.0588840127599128 | 0.0119348172836221 | COAD | Male-baised eQTL |
| rs7117203 | chr11:80955199:A:G | - | -0.0587878694512331 | 0.0121669375158586 | COAD | Male-baised eQTL |
| rs10793393 | chr11:79802145:A:G | - | -0.0585004811125779 | 0.0157696902172791 | COAD | Male-baised eQTL |
| rs10899687 | chr11:79802155:T:C | - | -0.0585004811125779 | 0.0157696902172791 | COAD | Male-baised eQTL |
| rs10793394 | chr11:79802428:T:A | - | -0.0585004811125779 | 0.0157696902172791 | COAD | Male-baised eQTL |
| rs11238001 | chr11:79803578:T:G | - | -0.0582601447315799 | 0.0165345464579361 | COAD | Male-baised eQTL |
| rs4945376 | chr11:79805854:G:A | - | -0.058248597600237 | 0.0165701751290833 | COAD | Male-baised eQTL |
| rs4944241 | chr11:79805942:C:T | - | -0.058248597600237 | 0.0165701751290833 | COAD | Male-baised eQTL |
| rs1815897 | chr11:79806371:C:T | - | -0.058248597600237 | 0.0165701751290833 | COAD | Male-baised eQTL |
| rs9787923 | chr11:79806666:G:T | - | -0.058248597600237 | 0.0165701751290833 | COAD | Male-baised eQTL |
| rs1320723 | chr11:79806673:G:C | - | -0.058248597600237 | 0.0165701751290833 | COAD | Male-baised eQTL |
| rs4944240 | chr11:79805811:T:C | - | -0.0576116179594502 | 0.0207492536162267 | COAD | Male-baised eQTL |
| rs10793392 | chr11:79802041:C:T | - | -0.0573063411845513 | 0.0209101764212444 | COAD | Male-baised eQTL |
| rs4945377 | chr11:79805959:A:G | - | -0.0567718274246648 | 0.0230988340492151 | COAD | Male-baised eQTL |
| rs624442 | chr11:79817859:C:A | - | -0.0566155421454233 | 0.0235388476228554 | COAD | Male-baised eQTL |
| rs10793395 | chr11:79806819:A:G | - | -0.0541198452020909 | 0.0272341948983043 | COAD | Male-baised eQTL |
| rs518179 | chr11:79818137:T:C | - | -0.0529447881334771 | 0.0437894708090623 | COAD | Male-baised eQTL |
| rs10792529 | chr11:80952838:G:T | - | -0.0535608048523119 | 0.0439830616491714 | COAD | Male-baised eQTL |
| rs11232399 | chr11:80920016:T:C | - | -0.0506879952281415 | 0.0495354817850197 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000188997 |
| CpG Site: cg06265811 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.161977628818691 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg06265811 | chr11:78185881 | gene | -0.161977628818691 | 2.98242708115596e-07 | -0.3781230322394711 | 4.327043444766367e-10 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of KCTD21 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
