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Gene: ENSG00000187498 |
Summary for COL4A1 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000187498 | Gene symbol | COL4A1 |
| Gene name | collagen type IV alpha 1 chain | |
| HGNC | 2202 | |
| Entrez ID | 1282 | |
| Gene type | protein_coding | |
| Synonyms | COL4A1| | |
| UniProtAcc | P02462 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for COL4A1 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| COL4A1 | 1.41e+04 | 1.92e+00 | 4.74e-01 | 4.05e+00 | 5.13e-05 | 2.43e-04 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| COL4A1 | 1.22e+04 | 1.58e+00 | 2.08e-01 | 7.63e+00 | 2.34e-14 | 2.14e-13 | COAD |
Top |
Sex-biased somatic mutation for COL4A1 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for COL4A1 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg06659727 | chr13:110307081 | CGI:chr13:110306544-110308243 | UTR,promoter,exon,gene body | 2.32e-01 | 3.87e-01 | -1.97e+00 | 4.94e-02 | 4.97e-02 | -1.55e-01 |
| BRCA | cg20327444 | chr13:110307300 | CGI:chr13:110306544-110308243 | promoter | 1.21e-01 | 3.65e-01 | -2.22e+00 | 2.67e-02 | 3.91e-02 | -2.45e-01 |
| BRCA | cg24089600 | chr13:110307830 | CGI:chr13:110306544-110308243 | promoter | 2.77e-01 | 4.92e-01 | -2.60e+00 | 9.30e-03 | 2.60e-02 | -2.15e-01 |
| BRCA | cg17541528 | chr13:110307303 | CGI:chr13:110306544-110308243 | promoter | 2.11e-01 | 3.96e-01 | -2.01e+00 | 4.50e-02 | 4.80e-02 | -1.85e-01 |
| BRCA | cg22757824 | chr13:110307839 | CGI:chr13:110306544-110308243 | promoter | 2.25e-01 | 4.53e-01 | -2.76e+00 | 5.83e-03 | 2.17e-02 | -2.29e-01 |
| BRCA | cg25530246 | chr13:110308216 | CGI:chr13:110306544-110308243 | promoter | 5.34e-02 | 2.09e-01 | -2.03e+00 | 4.22e-02 | 4.69e-02 | -1.55e-01 |
| BRCA | cg15871127 | chr13:110307851 | CGI:chr13:110306544-110308243 | promoter | 2.80e-01 | 4.33e-01 | -2.50e+00 | 1.25e-02 | 2.90e-02 | -1.53e-01 |
| BRCA | cg27546237 | chr13:110308105 | CGI:chr13:110306544-110308243 | promoter | 1.99e-01 | 3.97e-01 | -2.81e+00 | 4.98e-03 | 2.03e-02 | -1.99e-01 |
| PAAD | cg21938148 | chr13:110306630 | CGI:chr13:110306544-110308243 | promoter,gene body | 2.15e-01 | 3.28e-01 | -3.46e+00 | 5.36e-04 | 2.67e-03 | -1.13e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| HNSC | cg06659727 | chr13:110307081 | CGI:chr13:110306544-110308243 | UTR,promoter,exon,gene body | 2.11e-01 | 9.51e-02 | 2.94e+00 | 3.27e-03 | 4.96e-03 | 1.16e-01 |
| HNSC | cg01956420 | chr13:110307321 | CGI:chr13:110306544-110308243 | promoter | 1.74e-01 | 3.92e-02 | 2.92e+00 | 3.51e-03 | 5.26e-03 | 1.35e-01 |
| HNSC | cg24089600 | chr13:110307830 | CGI:chr13:110306544-110308243 | promoter | 2.11e-01 | 7.57e-02 | 2.71e+00 | 6.63e-03 | 9.04e-03 | 1.36e-01 |
| HNSC | cg21938148 | chr13:110306630 | CGI:chr13:110306544-110308243 | promoter,gene body | 1.21e-01 | 1.70e-02 | 2.95e+00 | 3.15e-03 | 4.80e-03 | 1.04e-01 |
| HNSC | cg17541528 | chr13:110307303 | CGI:chr13:110306544-110308243 | promoter | 1.79e-01 | 5.29e-02 | 2.51e+00 | 1.21e-02 | 1.50e-02 | 1.27e-01 |
| HNSC | cg22757824 | chr13:110307839 | CGI:chr13:110306544-110308243 | promoter | 1.78e-01 | 4.96e-02 | 2.98e+00 | 2.87e-03 | 4.44e-03 | 1.29e-01 |
| LUSC | cg01956420 | chr13:110307321 | CGI:chr13:110306544-110308243 | promoter | 1.35e-01 | 3.11e-02 | 2.98e+00 | 2.91e-03 | 5.47e-03 | 1.04e-01 |
| LUSC | cg17541528 | chr13:110307303 | CGI:chr13:110306544-110308243 | promoter | 1.50e-01 | 2.75e-02 | 3.12e+00 | 1.79e-03 | 3.87e-03 | 1.22e-01 |
| BLCA | cg06659727 | chr13:110307081 | CGI:chr13:110306544-110308243 | UTR,promoter,exon,gene body | 3.79e-01 | 1.60e-01 | 2.84e+00 | 4.50e-03 | 7.49e-03 | 2.18e-01 |
| BLCA | cg20327444 | chr13:110307300 | CGI:chr13:110306544-110308243 | promoter | 2.81e-01 | 6.75e-02 | 2.80e+00 | 5.12e-03 | 8.29e-03 | 2.14e-01 |
| BLCA | cg01956420 | chr13:110307321 | CGI:chr13:110306544-110308243 | promoter | 3.52e-01 | 1.15e-01 | 2.46e+00 | 1.39e-02 | 1.83e-02 | 2.38e-01 |
| BLCA | cg24089600 | chr13:110307830 | CGI:chr13:110306544-110308243 | promoter | 4.08e-01 | 1.04e-01 | 3.47e+00 | 5.13e-04 | 1.35e-03 | 3.04e-01 |
| BLCA | cg21938148 | chr13:110306630 | CGI:chr13:110306544-110308243 | promoter,gene body | 2.17e-01 | 1.81e-02 | 2.24e+00 | 2.48e-02 | 2.90e-02 | 1.99e-01 |
| BLCA | cg17541528 | chr13:110307303 | CGI:chr13:110306544-110308243 | promoter | 3.82e-01 | 1.17e-01 | 2.81e+00 | 4.89e-03 | 7.99e-03 | 2.65e-01 |
| BLCA | cg22757824 | chr13:110307839 | CGI:chr13:110306544-110308243 | promoter | 3.65e-01 | 6.43e-02 | 3.41e+00 | 6.40e-04 | 1.61e-03 | 3.00e-01 |
| BLCA | cg13596497 | chr13:110306757 | CGI:chr13:110306544-110308243 | promoter,gene body | 3.72e-01 | 1.31e-01 | 3.56e+00 | 3.66e-04 | 1.04e-03 | 2.41e-01 |
| BLCA | cg15871127 | chr13:110307851 | CGI:chr13:110306544-110308243 | promoter | 3.74e-01 | 1.78e-01 | 3.12e+00 | 1.79e-03 | 3.59e-03 | 1.96e-01 |
| BLCA | cg27546237 | chr13:110308105 | CGI:chr13:110306544-110308243 | promoter | 2.90e-01 | 1.06e-01 | 2.54e+00 | 1.12e-02 | 1.55e-02 | 1.84e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg06659727 | chr13:110307081 | CGI:chr13:110306544-110308243 | UTR,promoter,exon,gene body | 2.32e-01 | 8.26e-02 | 7.33e+00 | 2.23e-13 | 7.18e-13 | 1.49e-01 |
| BRCA | cg01956420 | chr13:110307321 | CGI:chr13:110306544-110308243 | promoter | 1.69e-01 | 4.12e-02 | 5.41e+00 | 6.20e-08 | 1.29e-07 | 1.28e-01 |
| BRCA | cg24089600 | chr13:110307830 | CGI:chr13:110306544-110308243 | promoter | 2.77e-01 | 5.59e-02 | 1.07e+01 | 1.23e-26 | 1.23e-25 | 2.21e-01 |
| BRCA | cg17541528 | chr13:110307303 | CGI:chr13:110306544-110308243 | promoter | 2.11e-01 | 4.89e-02 | 6.45e+00 | 1.09e-10 | 2.86e-10 | 1.62e-01 |
| BRCA | cg22757824 | chr13:110307839 | CGI:chr13:110306544-110308243 | promoter | 2.25e-01 | 4.36e-02 | 1.02e+01 | 2.49e-24 | 1.98e-23 | 1.81e-01 |
| BRCA | cg13596497 | chr13:110306757 | CGI:chr13:110306544-110308243 | promoter,gene body | 2.51e-01 | 8.61e-02 | 1.07e+01 | 7.90e-27 | 8.04e-26 | 1.65e-01 |
| BRCA | cg15871127 | chr13:110307851 | CGI:chr13:110306544-110308243 | promoter | 2.80e-01 | 1.36e-01 | 9.28e+00 | 1.75e-20 | 9.83e-20 | 1.44e-01 |
| BRCA | cg27546237 | chr13:110308105 | CGI:chr13:110306544-110308243 | promoter | 1.99e-01 | 6.53e-02 | 9.92e+00 | 3.45e-23 | 2.47e-22 | 1.33e-01 |
| LUAD | cg15262516 | chr13:110306071 | CGI:chr13:110306544-110308243 | promoter,gene body | 1.81e-01 | 7.92e-02 | 2.62e+00 | 8.75e-03 | 1.43e-02 | 1.02e-01 |
Top |
Exon skipping events with PSI in TCGA for COL4A1 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for COL4A1 |
| ∗Please access CAeditome for RNA editing annotation. |
| Landscape of RNA editing events across multiple cancer types. |
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| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| LUAD | COL4A1-006 | chr13_110289551_- | 2.91e-01 | 1.80e-01 | 2.60e+00 | 9.37e-03 | 2.78e-02 | 1.10e-01 |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for COL4A1 |
| TFs related to COL4A1. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| COL4A1 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for COL4A1 |
| RBPs related to ES in COL4A1. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| THYM | BRUNOL4 | exon_skip_104597 | 7.88e+00 | 8.43e-03 | 8.22e+00 | 9.84e-01 | Female-biased |
| THYM | BRUNOL5 | exon_skip_104597 | 7.90e+00 | 8.49e-03 | 8.23e+00 | 9.84e-01 | Female-biased |
| THYM | hnRNPLL | exon_skip_104597 | 7.79e+00 | 8.35e-03 | 8.12e+00 | 9.84e-01 | Female-biased |
| COAD | SAMD4A | exon_skip_104607 | 6.65e+00 | 9.82e-01 | 6.06e+00 | 9.58e-04 | Male-biased |
| DLBC | BRUNOL4 | exon_skip_104597 | 8.23e+00 | 9.86e-01 | 7.85e+00 | 6.31e-03 | Male-biased |
| DLBC | BRUNOL5 | exon_skip_104597 | 8.25e+00 | 9.86e-01 | 7.87e+00 | 6.29e-03 | Male-biased |
| DLBC | hnRNPLL | exon_skip_104597 | 8.14e+00 | 9.85e-01 | 7.76e+00 | 6.35e-03 | Male-biased |
| LUAD | SAMD4A | exon_skip_104598 | 8.54e+00 | 9.91e-01 | 8.09e+00 | 2.91e-03 | Male-biased |
| CHOL | IGF2BP1 | exon_skip_104608 | 1.03e+01 | 9.87e-01 | 9.94e+00 | 1.18e-02 | Male-biased |
| KIRP | SAMD4A | exon_skip_104598 | 8.48e+00 | 9.90e-01 | 8.06e+00 | 3.68e-03 | Male-biased |
| MESO | BRUNOL4 | exon_skip_104597 | 7.89e+00 | 6.27e-03 | 8.28e+00 | 9.86e-01 | Female-biased |
| MESO | BRUNOL5 | exon_skip_104597 | 7.91e+00 | 6.25e-03 | 8.30e+00 | 9.86e-01 | Female-biased |
| MESO | HNRNPH2 | exon_skip_104617 | 7.98e+00 | 6.90e-03 | 8.36e+00 | 9.86e-01 | Female-biased |
| MESO | hnRNPLL | exon_skip_104597 | 7.80e+00 | 6.34e-03 | 8.19e+00 | 9.86e-01 | Female-biased |
| MESO | SAMD4A | exon_skip_104607 | 7.12e+00 | 9.85e-01 | 6.61e+00 | 2.22e-03 | Male-biased |
| LGG | SAMD4A | exon_skip_104598 | 8.84e+00 | 9.88e-01 | 8.48e+00 | 7.17e-03 | Male-biased |
| GBM | IGF2BP1 | exon_skip_104608 | 9.96e+00 | 9.98e-03 | 1.03e+01 | 9.89e-01 | Female-biased |
| PAAD | HNRNPH2 | exon_skip_104617 | 7.98e+00 | 7.78e-03 | 8.30e+00 | 9.85e-01 | Female-biased |
| KICH | SAMD4A | exon_skip_104598 | 8.18e+00 | 5.63e-03 | 8.55e+00 | 9.88e-01 | Female-biased |
| BLCA | SAMD4A | exon_skip_104598 | 8.00e+00 | 4.86e-03 | 8.42e+00 | 9.88e-01 | Female-biased |
| HNSC | SAMD4A | exon_skip_104598 | 7.94e+00 | 2.92e-04 | 8.63e+00 | 9.94e-01 | Female-biased |
| COL4A1 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs79193277 | chr13:110091218:G:A | - | 0.11558932735068 | 0.0402449620703177 | LUSC | Female-baised eQTL |
| rs56119221 | chr13:113234407:C:G | - | 0.0476439042112592 | 0.0215108806156504 | LUAD | Female-baised eQTL |
| rs72658216 | chr13:109187956:C:T | - | 0.0508341069052853 | 0.0471153904655932 | LUAD | Female-baised eQTL |
| rs76277274 | chr13:100303686:A:C | - | 0.0526323403473776 | 0.0473923295660315 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs1298629 | chr13:105950373:A:G | - | -0.113486503826197 | 0.000335748158642006 | STAD | Male-baised eQTL |
| rs2249748 | chr13:105954547:G:T | - | -0.0895117634010846 | 0.0185286148896685 | STAD | Male-baised eQTL |
| rs9586621 | chr13:104746350:G:A | - | 0.0911230602399991 | 0.0062675083838947 | BLCA | Male-baised eQTL |
| rs9300965 | chr13:104747444:C:T | - | 0.0760247449483602 | 0.0344369127528052 | BLCA | Male-baised eQTL |
| rs9300967 | chr13:104749797:A:G | - | 0.0764549395464586 | 0.0426434259860103 | BLCA | Male-baised eQTL |
| rs61239565 | chr13:110002113:G:A | - | 0.140284335066014 | 0.00115273286002479 | COAD | Male-baised eQTL |
| rs183711260 | chr13:109992109:A:T | - | 0.144182177483595 | 0.00137768939515976 | COAD | Male-baised eQTL |
| rs144036587 | chr13:109993294:A:C | - | 0.144182177483595 | 0.00137768939515976 | COAD | Male-baised eQTL |
| rs79751079 | chr13:109995555:T:A | - | 0.14208535412406 | 0.00142964157408026 | COAD | Male-baised eQTL |
| rs3742209 | chr13:109986013:G:A | - | 0.1432626658694 | 0.00155079972827515 | COAD | Male-baised eQTL |
| rs7998434 | chr13:110007018:T:C | - | 0.137696942995841 | 0.00248982869732914 | COAD | Male-baised eQTL |
| rs373605189 | chr13:103069767:G:A | - | 0.145762911334536 | 0.00270506347222877 | COAD | Male-baised eQTL |
| rs77118982 | chr13:103075484:A:G | - | 0.145762911334536 | 0.00270506347222877 | COAD | Male-baised eQTL |
| rs77324237 | chr13:103076098:G:C | - | 0.145762911334536 | 0.00270506347222877 | COAD | Male-baised eQTL |
| rs75595545 | chr13:103079360:T:G | - | 0.145135873268697 | 0.00291804630218765 | COAD | Male-baised eQTL |
| rs1540461 | chr13:101696166:A:G | - | 0.0748852444588611 | 0.00307337298429486 | COAD | Male-baised eQTL |
| rs73618805 | chr13:110012079:C:G | - | 0.143200542245375 | 0.00323361904957098 | COAD | Male-baised eQTL |
| rs1540460 | chr13:101696355:A:T | - | 0.0728109007571005 | 0.00370197054387937 | COAD | Male-baised eQTL |
| rs7994568 | chr13:106145017:A:G | - | 0.0850154586568322 | 0.00832285103289039 | COAD | Male-baised eQTL |
| rs9514512 | chr13:106237418:T:A | - | 0.12331956797149 | 0.009512410320104 | COAD | Male-baised eQTL |
| rs16968630 | chr13:106445562:G:C | - | 0.095680194544211 | 0.0117046177052615 | COAD | Male-baised eQTL |
| rs35174640 | chr13:106607761:G:A | - | 0.0546303873377186 | 0.0205540864185893 | COAD | Male-baised eQTL |
| rs4771752 | chr13:111433525:A:C | - | 0.056464979722041 | 0.0212921705569297 | COAD | Male-baised eQTL |
| rs9555796 | chr13:111433099:C:A | - | 0.0561016579506275 | 0.0220645436745865 | COAD | Male-baised eQTL |
| rs4771751 | chr13:111433513:A:G | - | 0.0560948215805329 | 0.0220695782863303 | COAD | Male-baised eQTL |
| rs9587782 | chr13:109144444:A:G | - | 0.0794258969945268 | 0.0253360966711384 | COAD | Male-baised eQTL |
| rs35763512 | chr13:109397244:G:A | - | 0.0740743745015828 | 0.0259602833445229 | COAD | Male-baised eQTL |
| rs61972637 | chr13:106027430:A:G | - | 0.0846221375948041 | 0.0298855113626536 | COAD | Male-baised eQTL |
| rs2893073 | chr13:101690493:A:G | - | 0.0587923022582793 | 0.0302769876492819 | COAD | Male-baised eQTL |
| rs12430541 | chr13:109984580:C:A | - | 0.0896074349772111 | 0.0371503124409479 | COAD | Male-baised eQTL |
| rs9518498 | chr13:101705147:A:G | - | 0.0566985129683735 | 0.0389591591971647 | COAD | Male-baised eQTL |
| rs1436264 | chr13:101689258:G:C | - | 0.0582236421517247 | 0.0396159673494251 | COAD | Male-baised eQTL |
| rs61972635 | chr13:106021775:C:T | - | 0.0815663093185653 | 0.0399175402145721 | COAD | Male-baised eQTL |
| rs61972636 | chr13:106025618:A:G | - | 0.0815663093185653 | 0.0399175402145721 | COAD | Male-baised eQTL |
| rs16961281 | chr13:103066474:G:A | - | 0.107088899750783 | 0.0458672065967834 | COAD | Male-baised eQTL |
| rs12429986 | chr13:109982695:G:A | - | 0.0862162312679476 | 0.0468046158098982 | COAD | Male-baised eQTL |
| rs9301351 | chr13:109084425:C:T | - | 0.0833892571075868 | 0.0480920574272739 | COAD | Male-baised eQTL |
| rs9521350 | chr13:109403777:C:T | - | 0.0655852675828834 | 0.0487662095953665 | COAD | Male-baised eQTL |
| rs9518915 | chr13:103061969:T:G | - | 0.096987028523344 | 0.0491034199861454 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000187498 |
| CpG Site: cg02658690 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.450467640589683 | |
 | Gene ID: ENSG00000187498 |
| CpG Site: cg20818806 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.450467640589683 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg02658690 | chr13:110233499 | gene | -0.450467640589683 | 1.36223663353247e-22 | -0.6083362739720963 | 3.335536774605328e-27 | LUAD |
| cg20818806 | chr13:110233579 | gene | -0.450467640589683 | 1.36223663353247e-22 | -0.6083362739720963 | 3.335536774605328e-27 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of COL4A1 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000187498 | COL4A1 | C0002878 | Anemia, Hemolytic | 1 | CTD_human |
| ENSG00000187498 | COL4A1 | C0002879 | Anemia, Hemolytic, Acquired | 1 | CTD_human |
| ENSG00000187498 | COL4A1 | C0002889 | Anemia, Microangiopathic | 1 | CTD_human |
| ENSG00000187498 | COL4A1 | C0011881 | Diabetic Nephropathy | 2 | CTD_human |
| ENSG00000187498 | COL4A1 | C0015393 | Eye Abnormalities | 1 | CTD_human |
| ENSG00000187498 | COL4A1 | C0017667 | Nodular glomerulosclerosis | 2 | CTD_human |
| ENSG00000187498 | COL4A1 | C0017668 | Focal glomerulosclerosis | 2 | CTD_human |
| ENSG00000187498 | COL4A1 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| ENSG00000187498 | COL4A1 | C0027726 | Nephrotic Syndrome | 1 | CTD_human |
| ENSG00000187498 | COL4A1 | C0086432 | Hyalinosis, Segmental Glomerular | 2 | CTD_human |
| ENSG00000187498 | COL4A1 | C0221021 | Microangiopathic hemolytic anemia | 1 | CTD_human |
| ENSG00000187498 | COL4A1 | C0265341 | Rieger syndrome | 2 | CTD_human |
| ENSG00000187498 | COL4A1 | C0266484 | Schizencephaly | 1 | CTD_human |
| ENSG00000187498 | COL4A1 | C0266548 | Axenfeld anomaly (disorder) | 2 | CTD_human |
| ENSG00000187498 | COL4A1 | C0270612 | Leukoencephalopathy | 1 | CTD_human |
| ENSG00000187498 | COL4A1 | C0302892 | Congenital porencephaly | 2 | CTD_human |
| ENSG00000187498 | COL4A1 | C1135196 | Heart Failure, Diastolic | 1 | CTD_human |
| ENSG00000187498 | COL4A1 | C1280768 | Axenfeld syndrome | 2 | CTD_human |
| ENSG00000187498 | COL4A1 | C1843512 | BRAIN SMALL VESSEL DISEASE WITH HEMORRHAGE | 2 | CTD_human |
| ENSG00000187498 | COL4A1 | C1858991 | Childhood Ataxia with Central Nervous System Hypomyelinization | 1 | CTD_human |
| ENSG00000187498 | COL4A1 | C1867327 | RETINAL ARTERIES, TORTUOSITY OF | 1 | CTD_human |
| ENSG00000187498 | COL4A1 | C1867983 | PORENCEPHALY, FAMILIAL | 2 | CTD_human |
| ENSG00000187498 | COL4A1 | C2673195 | Angiopathy, Hereditary, With Nephropathy, Aneurysms, And Muscle Cramps | 1 | CTD_human |
| ENSG00000187498 | COL4A1 | C2675650 | Brain Small Vessel Disease With Axenfeld-Rieger Anomaly | 2 | CTD_human |
| ENSG00000187498 | COL4A1 | C2678503 | AXENFELD-RIEGER SYNDROME, TYPE 3 | 2 | CTD_human |
| ENSG00000187498 | COL4A1 | C2937358 | Cerebral Hemorrhage | 1 | CTD_human |
| ENSG00000187498 | COL4A1 | C3495488 | Axenfeld-Rieger syndrome | 2 | CTD_human |
| ENSG00000187498 | COL4A1 | C3698507 | Post-traumatic Porencephaly | 2 | CTD_human |
| ENSG00000187498 | COL4A1 | C3714873 | Axenfeld-Rieger Syndrome, Type 1 | 2 | CTD_human |
| ENSG00000187498 | COL4A1 | C4082173 | Porencephaly | 2 | CTD_human |
| ENSG00000187498 | COL4A1 | C4082301 | Developmental Porencephaly | 2 | CTD_human |
| ENSG00000187498 | COL4A1 | C4551998 | Porencephaly, Type 1, Autosomal Dominant | 2 | CTD_human |
