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Gene: ENSG00000187091 |
Summary for PLCD1 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000187091 | Gene symbol | PLCD1 |
| Gene name | phospholipase C delta 1 | |
| HGNC | 9060 | |
| Entrez ID | 5333 | |
| Gene type | protein_coding | |
| Synonyms | PLCD1| | |
| UniProtAcc | P51178 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for PLCD1 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| PLCD1 | 2.44e+03 | 1.02e+00 | 1.62e-01 | 6.31e+00 | 2.88e-10 | 3.43e-09 | THCA |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| PLCD1 | 8.11e+02 | -1.29e+00 | 2.71e-01 | -4.75e+00 | 2.00e-06 | 1.60e-05 | READ |
Top |
Sex-biased somatic mutation for PLCD1 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for PLCD1 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| HNSC | cg12705340 | chr3:38028851 | CGI:chr3:38028903-38030107 | promoter,gene body | 6.99e-01 | 5.66e-01 | 4.69e+00 | 2.77e-06 | 1.32e-05 | 1.33e-01 |
| LIHC | cg02067846 | chr3:38030007 | CGI:chr3:38028903-38030107 | promoter | 1.20e-01 | 1.93e-02 | 2.24e+00 | 2.52e-02 | 2.74e-02 | 1.01e-01 |
| LIHC | cg23971255 | chr3:38029810 | CGI:chr3:38028903-38030107 | promoter | 1.36e-01 | 3.02e-02 | 2.28e+00 | 2.28e-02 | 2.51e-02 | 1.06e-01 |
| LIHC | cg25773620 | chr3:38029818 | CGI:chr3:38028903-38030107 | promoter | 1.44e-01 | 2.74e-02 | 2.92e+00 | 3.46e-03 | 4.76e-03 | 1.16e-01 |
| LIHC | cg15120942 | chr3:38030087 | CGI:chr3:38028903-38030107 | promoter | 5.32e-01 | 4.27e-01 | 3.23e+00 | 1.24e-03 | 1.92e-03 | 1.05e-01 |
| ESCA | cg15120942 | chr3:38030087 | CGI:chr3:38028903-38030107 | promoter | 4.68e-01 | 3.19e-01 | 2.81e+00 | 4.96e-03 | 3.43e-02 | 1.49e-01 |
| CHOL | cg03819243 | chr3:38031120 | CGI:chr3:38028903-38030107 | promoter | 5.64e-01 | 7.46e-01 | -2.06e+00 | 3.90e-02 | 4.26e-02 | -1.82e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg02067846 | chr3:38030007 | CGI:chr3:38028903-38030107 | promoter | 1.53e-01 | 2.31e-02 | 8.25e+00 | 1.61e-16 | 6.57e-16 | 1.29e-01 |
| BRCA | cg12705340 | chr3:38028851 | CGI:chr3:38028903-38030107 | promoter,gene body | 8.06e-01 | 6.58e-01 | 1.30e+01 | 1.09e-38 | 6.34e-37 | 1.48e-01 |
| BRCA | cg24868271 | chr3:38028969 | CGI:chr3:38028903-38030107 | promoter,gene body | 7.52e-01 | 6.19e-01 | 1.18e+01 | 6.61e-32 | 1.23e-30 | 1.33e-01 |
| BRCA | cg01614883 | chr3:38029443 | CGI:chr3:38028903-38030107 | promoter,gene body | 2.51e-01 | 1.06e-01 | 7.03e+00 | 2.07e-12 | 6.19e-12 | 1.45e-01 |
| BRCA | cg15120942 | chr3:38030087 | CGI:chr3:38028903-38030107 | promoter | 5.38e-01 | 3.56e-01 | 1.04e+01 | 1.72e-25 | 1.53e-24 | 1.82e-01 |
| LUAD | cg01614883 | chr3:38029443 | CGI:chr3:38028903-38030107 | promoter,gene body | 1.60e-01 | 5.75e-02 | 3.66e+00 | 2.56e-04 | 1.39e-03 | 1.03e-01 |
| HNSC | cg03819243 | chr3:38031120 | CGI:chr3:38028903-38030107 | promoter | 5.55e-01 | 3.75e-01 | 2.69e+00 | 7.10e-03 | 1.57e-02 | 1.81e-01 |
| LIHC | cg03819243 | chr3:38031120 | CGI:chr3:38028903-38030107 | promoter | 7.54e-01 | 8.60e-01 | -2.17e+00 | 3.00e-02 | 3.33e-02 | -1.06e-01 |
Top |
Exon skipping events with PSI in TCGA for PLCD1 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
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| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for PLCD1 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for PLCD1 |
| TFs related to PLCD1. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| PLCD1 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for PLCD1 |
| RBPs related to ES in PLCD1. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| STAD | ZC3H10 | exon_skip_382435 | 7.74e+00 | 9.85e-01 | 7.33e+00 | 5.55e-03 | Male-biased |
| UVM | RBM4 | exon_skip_382430 | 6.69e+00 | 1.90e-03 | 7.14e+00 | 9.85e-01 | Female-biased |
| THYM | RBM4 | exon_skip_382430 | 7.08e+00 | 7.64e-03 | 7.42e+00 | 9.81e-01 | Female-biased |
| THYM | RBM4 | exon_skip_382434 | 7.25e+00 | 6.01e-03 | 7.62e+00 | 9.84e-01 | Female-biased |
| THYM | SAMD4A | exon_skip_382435 | 6.50e+00 | 4.71e-03 | 6.88e+00 | 9.81e-01 | Female-biased |
| LUAD | RBM4 | exon_skip_382429 | 8.72e+00 | 9.88e-01 | 8.35e+00 | 6.15e-03 | Male-biased |
| BRCA | SAMD4A | exon_skip_382435 | 6.76e+00 | 9.10e-03 | 7.42e+00 | 9.80e-01 | Female-biased |
| READ | SAMD4A | exon_skip_382435 | 6.86e+00 | 9.84e-01 | 6.33e+00 | 1.23e-03 | Male-biased |
| BLCA | RBM4 | exon_skip_382429 | 8.45e+00 | 9.85e-01 | 8.06e+00 | 7.81e-03 | Male-biased |
| BLCA | SAMD4A | exon_skip_382435 | 7.43e+00 | 9.88e-01 | 6.77e+00 | 8.95e-04 | Male-biased |
| BLCA | ZC3H10 | exon_skip_382435 | 7.96e+00 | 9.86e-01 | 7.53e+00 | 5.43e-03 | Male-biased |
| SKCM | RBM4 | exon_skip_382429 | 8.40e+00 | 7.32e-03 | 8.79e+00 | 9.88e-01 | Female-biased |
| SARC | SAMD4A | exon_skip_382435 | 6.60e+00 | 3.38e-03 | 7.07e+00 | 9.83e-01 | Female-biased |
| PLCD1 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs77969935 | chr3:36211741:A:G | - | 0.271553478096732 | 0.0099075274250329 | KIRP | Female-baised eQTL |
| rs79996299 | chr3:36212158:A:G | - | 0.271553478096732 | 0.0099075274250329 | KIRP | Female-baised eQTL |
| rs73830906 | chr3:36214636:T:C | - | 0.271553478096732 | 0.0099075274250329 | KIRP | Female-baised eQTL |
| rs3912155 | chr3:36218034:A:G | - | 0.271553478096732 | 0.0099075274250329 | KIRP | Female-baised eQTL |
| rs73830911 | chr3:36225572:A:T | - | 0.271553478096732 | 0.0099075274250329 | KIRP | Female-baised eQTL |
| rs73830905 | chr3:36214476:C:T | - | 0.259359067483808 | 0.0110630508200876 | KIRP | Female-baised eQTL |
| rs73830914 | chr3:36240131:A:G | - | 0.258198561460391 | 0.0122439705516215 | KIRP | Female-baised eQTL |
| rs73830916 | chr3:36240492:G:A | - | 0.258198561460391 | 0.0122439705516215 | KIRP | Female-baised eQTL |
| rs73830918 | chr3:36243068:T:C | - | 0.258198561460391 | 0.0122439705516215 | KIRP | Female-baised eQTL |
| rs10510682 | chr3:36256733:T:G | - | 0.276227930445237 | 0.0166689012179851 | KIRP | Female-baised eQTL |
| rs73827806 | chr3:36256960:C:G | - | 0.276227930445237 | 0.0166689012179851 | KIRP | Female-baised eQTL |
| rs11714737 | chr3:30928673:A:G | - | 0.0998218773979921 | 0.0140933741896381 | LUSC | Female-baised eQTL |
| rs11710806 | chr3:30883082:T:A | - | 0.0867110301527041 | 0.0410369339804103 | LUSC | Female-baised eQTL |
| rs73065054 | chr3:30885140:G:A | - | 0.0867110301527041 | 0.0410369339804103 | LUSC | Female-baised eQTL |
| rs73065060 | chr3:30889660:C:T | - | 0.0867110301527041 | 0.0410369339804103 | LUSC | Female-baised eQTL |
| rs73065074 | chr3:30896392:A:G | - | 0.0865787768514594 | 0.0425859009343823 | LUSC | Female-baised eQTL |
| rs79251223 | chr3:30898586:C:A | - | 0.0865787768514594 | 0.0425859009343823 | LUSC | Female-baised eQTL |
| rs55687702 | chr3:30900139:G:C | - | 0.0865787768514594 | 0.0425859009343823 | LUSC | Female-baised eQTL |
| rs146148580 | chr3:42240094:G:C | - | 0.228789055787356 | 0.00243343756978958 | STAD | Female-baised eQTL |
| rs150750076 | chr3:42240145:T:A | - | 0.228789055787356 | 0.00243343756978958 | STAD | Female-baised eQTL |
| rs1495693 | chr3:41518601:C:T | - | -0.0987214058014639 | 0.0399283931325559 | KIRC | Female-baised eQTL |
| rs9870792 | chr3:41290490:G:C | - | 0.0807052093709147 | 0.0424450883010727 | KIRC | Female-baised eQTL |
| rs59575722 | chr3:41289898:G:A | - | 0.080141220877891 | 0.0468884807806727 | KIRC | Female-baised eQTL |
| rs6773779 | chr3:41336337:C:T | - | 0.0844586252713727 | 0.0481954998383164 | KIRC | Female-baised eQTL |
| rs9826643 | chr3:41288978:A:C | - | 0.0791027617978542 | 0.049837755978125 | KIRC | Female-baised eQTL |
| rs9826776 | chr3:41289069:A:G | - | 0.0791027617978542 | 0.049837755978125 | KIRC | Female-baised eQTL |
| rs72896290 | chr3:28157712:T:G | - | 0.106134437661855 | 0.00513953871766414 | LUAD | Female-baised eQTL |
| rs17710733 | chr3:28170222:G:A | - | 0.0930644503174088 | 0.0173796317191493 | LUAD | Female-baised eQTL |
| rs113508588 | chr3:33474368:T:G | - | 0.0766811596212244 | 0.0499480326277422 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs6549908 | chr3:29027617:G:A | - | -0.0981452252309461 | 0.0120394136093272 | STAD | Male-baised eQTL |
| rs113213588 | chr3:38008668:G:A | gene,exon | 0.0805987865709481 | 0.0354041443405861 | STAD | Male-baised eQTL |
| rs76817219 | chr3:37999855:G:A | - | 0.0762719895885415 | 0.0424641968607575 | STAD | Male-baised eQTL |
| rs59855940 | chr3:32393938:T:C | - | 0.0712501602492208 | 0.0478219537336927 | STAD | Male-baised eQTL |
| rs76439043 | chr3:38004978:C:T | - | 0.0758629873485664 | 0.0485194842937483 | STAD | Male-baised eQTL |
| rs11707277 | chr3:38006189:G:A | - | 0.0758629873485664 | 0.0485194842937483 | STAD | Male-baised eQTL |
| rs4630916 | chr3:43438680:A:G | - | -0.0587903027610925 | 0.00534362396418787 | KIRC | Male-baised eQTL |
| rs977911 | chr3:43392065:T:G | - | -0.0514694743991668 | 0.0344677224432825 | KIRC | Male-baised eQTL |
| rs6800209 | chr3:39330021:G:A | - | 0.0747724043368685 | 0.000615503343354286 | LUAD | Male-baised eQTL |
| rs73060988 | chr3:29027895:A:G | - | 0.0651495341284823 | 0.000745459596973725 | LUAD | Male-baised eQTL |
| rs116087708 | chr3:29031152:C:T | - | 0.0650221773181563 | 0.000785871536174293 | LUAD | Male-baised eQTL |
| rs73060996 | chr3:29031481:G:A | - | 0.0650221773181563 | 0.000785871536174293 | LUAD | Male-baised eQTL |
| rs73060999 | chr3:29034760:T:C | - | 0.0649445833766299 | 0.000813547022263186 | LUAD | Male-baised eQTL |
| rs73061001 | chr3:29034781:T:C | - | 0.0649445833766299 | 0.000813547022263186 | LUAD | Male-baised eQTL |
| rs73062706 | chr3:29039794:G:A | - | 0.0649445833766299 | 0.000813547022263186 | LUAD | Male-baised eQTL |
| rs73062708 | chr3:29039951:G:T | - | 0.0649445833766299 | 0.000813547022263186 | LUAD | Male-baised eQTL |
| rs73060977 | chr3:29021460:A:G | - | 0.0648883414920998 | 0.000826128105620694 | LUAD | Male-baised eQTL |
| rs73055308 | chr3:29009543:C:T | - | 0.064831567743057 | 0.000848158989070953 | LUAD | Male-baised eQTL |
| rs1449691 | chr3:29010530:G:T | - | 0.064831567743057 | 0.000848158989070953 | LUAD | Male-baised eQTL |
| rs17718700 | chr3:29013654:T:C | - | 0.064831567743057 | 0.000848158989070953 | LUAD | Male-baised eQTL |
| rs73055303 | chr3:29008466:T:C | - | 0.0647527105722753 | 0.000877402783744493 | LUAD | Male-baised eQTL |
| rs73053394 | chr3:29006259:T:A | - | 0.0644402280697206 | 0.000982470148222445 | LUAD | Male-baised eQTL |
| rs17662802 | chr3:29048597:C:T | - | 0.0624684195671302 | 0.00153251935715482 | LUAD | Male-baised eQTL |
| rs1960344 | chr3:29050259:G:A | - | 0.0624684195671302 | 0.00153251935715482 | LUAD | Male-baised eQTL |
| rs150303903 | chr3:29051333:T:C | - | 0.0624684195671302 | 0.00153251935715482 | LUAD | Male-baised eQTL |
| rs146029212 | chr3:29051735:A:T | - | 0.0624684195671302 | 0.00153251935715482 | LUAD | Male-baised eQTL |
| rs114228470 | chr3:29051820:C:T | - | 0.0624684195671302 | 0.00153251935715482 | LUAD | Male-baised eQTL |
| rs116061381 | chr3:29052087:T:A | - | 0.0624684195671302 | 0.00153251935715482 | LUAD | Male-baised eQTL |
| rs73062719 | chr3:29055993:G:A | - | 0.0624684195671302 | 0.00153251935715482 | LUAD | Male-baised eQTL |
| rs55759409 | chr3:29042805:A:G | - | 0.0624624412659668 | 0.00154383971494625 | LUAD | Male-baised eQTL |
| rs73062722 | chr3:29058989:C:T | - | 0.0616243655623834 | 0.00163523046613017 | LUAD | Male-baised eQTL |
| rs55728113 | chr3:29004034:G:A | - | 0.0629479342625203 | 0.00214164349254479 | LUAD | Male-baised eQTL |
| rs35934336 | chr3:39136946:G:T | - | 0.0680837130440111 | 0.0026167025287538 | LUAD | Male-baised eQTL |
| rs143823089 | chr3:29060567:G:A | - | 0.0595652613462867 | 0.00266542884960128 | LUAD | Male-baised eQTL |
| rs73062729 | chr3:29061582:C:G | - | 0.0595652613462867 | 0.00266542884960128 | LUAD | Male-baised eQTL |
| rs73062731 | chr3:29062240:A:G | - | 0.0595652613462867 | 0.00266542884960128 | LUAD | Male-baised eQTL |
| rs73062732 | chr3:29063281:T:C | - | 0.0595652613462867 | 0.00266542884960128 | LUAD | Male-baised eQTL |
| rs17662956 | chr3:29064184:G:A | - | 0.0595652613462867 | 0.00266542884960128 | LUAD | Male-baised eQTL |
| rs17663087 | chr3:29068799:G:A | - | 0.0594241881487209 | 0.00280378242894197 | LUAD | Male-baised eQTL |
| rs74366044 | chr3:39055918:T:C | - | 0.0679877081467487 | 0.003551711593471 | LUAD | Male-baised eQTL |
| rs62242305 | chr3:38939067:G:T | - | 0.0679844202898794 | 0.00355465209344063 | LUAD | Male-baised eQTL |
| rs62242307 | chr3:38957447:C:T | - | 0.0679844202898794 | 0.00355465209344063 | LUAD | Male-baised eQTL |
| rs116242621 | chr3:38913596:A:T | - | 0.0679136048302697 | 0.00361396025777859 | LUAD | Male-baised eQTL |
| rs62242310 | chr3:39023674:G:A | - | 0.0679136048302697 | 0.00361396025777859 | LUAD | Male-baised eQTL |
| rs11922022 | chr3:38853092:C:T | - | 0.0677923241801173 | 0.00375300144723621 | LUAD | Male-baised eQTL |
| rs139783078 | chr3:38902641:C:T | - | 0.067706648694827 | 0.00384483215177455 | LUAD | Male-baised eQTL |
| rs73062741 | chr3:29078211:G:C | - | 0.0626478454615669 | 0.00421974305804505 | LUAD | Male-baised eQTL |
| rs62242263 | chr3:38905780:C:T | - | 0.0614368259988056 | 0.00450009265027024 | LUAD | Male-baised eQTL |
| rs73062739 | chr3:29075784:G:T | - | 0.0600074665340359 | 0.00489236853645935 | LUAD | Male-baised eQTL |
| rs17663159 | chr3:29076151:C:T | - | 0.0600074665340359 | 0.00489236853645935 | LUAD | Male-baised eQTL |
| rs73062740 | chr3:29076444:T:A | - | 0.0600074665340359 | 0.00489236853645935 | LUAD | Male-baised eQTL |
| rs62243833 | chr3:36628510:C:A | - | 0.0471556913785246 | 0.0062175728600273 | LUAD | Male-baised eQTL |
| rs1367610 | chr3:30655838:C:G | - | -0.0469788407859798 | 0.00622490414830955 | LUAD | Male-baised eQTL |
| rs1870703 | chr3:30649586:C:T | - | -0.0458809451550748 | 0.00823829739305602 | LUAD | Male-baised eQTL |
| rs2029314 | chr3:30650727:T:C | - | -0.0458809451550748 | 0.00823829739305602 | LUAD | Male-baised eQTL |
| rs1841528 | chr3:30659361:T:C | - | -0.0458454247526478 | 0.00851207783061282 | LUAD | Male-baised eQTL |
| rs62243838 | chr3:36643366:T:C | - | 0.0458324011361653 | 0.00962207143029213 | LUAD | Male-baised eQTL |
| rs6790424 | chr3:30649846:C:G | - | -0.0450825063447297 | 0.0100140339866028 | LUAD | Male-baised eQTL |
| rs139375826 | chr3:36622587:C:T | - | 0.0450210532188007 | 0.0103671735237165 | LUAD | Male-baised eQTL |
| rs6793609 | chr3:36623609:G:A | - | 0.0450210532188007 | 0.0103671735237165 | LUAD | Male-baised eQTL |
| rs62243836 | chr3:36637656:A:G | - | 0.0459401387088881 | 0.0106085949169049 | LUAD | Male-baised eQTL |
| rs115099187 | chr3:39188948:G:A | - | 0.0628685396563263 | 0.0106661017553877 | LUAD | Male-baised eQTL |
| rs28879210 | chr3:36653648:A:G | - | 0.0431176281056581 | 0.0108269902043283 | LUAD | Male-baised eQTL |
| rs62245169 | chr3:36659525:C:T | - | 0.0431176281056581 | 0.0108269902043283 | LUAD | Male-baised eQTL |
| rs1872978 | chr3:30654759:T:C | - | -0.0442192181299578 | 0.0124864804448349 | LUAD | Male-baised eQTL |
| rs62243834 | chr3:36629726:C:A | - | 0.0444543450524434 | 0.0135623186095824 | LUAD | Male-baised eQTL |
| rs34629244 | chr3:33062715:G:A | - | 0.0540869574627613 | 0.0136400479252187 | LUAD | Male-baised eQTL |
| rs35894066 | chr3:33061620:T:C | - | 0.0540134394966597 | 0.0138386625689394 | LUAD | Male-baised eQTL |
| rs6550007 | chr3:30660309:T:C | - | -0.0428902626509647 | 0.0153586874109855 | LUAD | Male-baised eQTL |
| rs7617990 | chr3:36647994:T:C | - | 0.042302333027813 | 0.0157471511665823 | LUAD | Male-baised eQTL |
| rs991694 | chr3:30660648:A:G | - | -0.0442913433967559 | 0.0162963114494593 | LUAD | Male-baised eQTL |
| rs6782113 | chr3:36660566:C:A | - | 0.0407719426284542 | 0.0168304994866317 | LUAD | Male-baised eQTL |
| rs62243830 | chr3:36620975:G:A | - | 0.0423622991870153 | 0.0172281443233756 | LUAD | Male-baised eQTL |
| rs74424834 | chr3:36631247:G:A | - | 0.0434277601755473 | 0.0174161718367666 | LUAD | Male-baised eQTL |
| rs77134736 | chr3:36631248:C:A | - | 0.0434277601755473 | 0.0174161718367666 | LUAD | Male-baised eQTL |
| rs7614776 | chr3:33097052:A:G | - | -0.0511712478340986 | 0.0182914846229639 | LUAD | Male-baised eQTL |
| rs112185687 | chr3:46598958:G:A | - | 0.058672530782995 | 0.0193557248479871 | LUAD | Male-baised eQTL |
| rs13059694 | chr3:45428330:A:G | - | 0.0392268367018889 | 0.020119815892596 | LUAD | Male-baised eQTL |
| rs13059851 | chr3:45428332:C:T | - | 0.0392268367018889 | 0.020119815892596 | LUAD | Male-baised eQTL |
| rs76861076 | chr3:33064884:A:G | - | 0.0509778514149884 | 0.0233236887520098 | LUAD | Male-baised eQTL |
| rs34204221 | chr3:33065568:A:G | - | 0.0509778514149884 | 0.0233236887520098 | LUAD | Male-baised eQTL |
| rs67261579 | chr3:44042836:C:T | - | 0.0441594743918433 | 0.0329021188520652 | LUAD | Male-baised eQTL |
| rs77007474 | chr3:39204422:C:A | - | 0.0548169009180505 | 0.033363823209982 | LUAD | Male-baised eQTL |
| rs506756 | chr3:42309951:A:G | - | -0.0367610516069071 | 0.0340081652375266 | LUAD | Male-baised eQTL |
| rs12639303 | chr3:39245393:T:C | - | 0.0439429842762881 | 0.0380871371736028 | LUAD | Male-baised eQTL |
| rs1463513 | chr3:30652643:A:T | - | -0.0365655078847614 | 0.049784846040291 | LUAD | Male-baised eQTL |
| rs7617990 | chr3:36647994:T:C | - | 0.0706584199454703 | 0.0333961928860478 | COAD | Male-baised eQTL |
| rs74388308 | chr3:45346335:T:C | - | 0.0927144833761896 | 0.0368190343697967 | COAD | Male-baised eQTL |
| rs929578 | chr3:45330113:G:T | - | 0.0528306359577828 | 0.0389188122036337 | COAD | Male-baised eQTL |
| rs62242418 | chr3:45333085:T:C | - | 0.0520980847872245 | 0.0393393622407466 | COAD | Male-baised eQTL |
| rs2218879 | chr3:32081842:T:G | - | -0.0632528428058127 | 0.0458317185714667 | COAD | Male-baised eQTL |
| rs62242415 | chr3:45321800:G:T | - | 0.0505000875349164 | 0.0493145882306384 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000187091 |
| CpG Site: cg24868271 | |
| Position to Gene: gene,promoter | |
| Male Effect: -0.382412834363117 | |
| Female Effect: - | |
 | Gene ID: ENSG00000187091 |
| CpG Site: cg15120942 | |
| Position to Gene: promoter | |
| Male Effect: -0.178151064700689 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg24868271 | chr3:38028969 | gene,promoter | -0.382412834363117 | 2.43997328908854e-05 | -0.36561451033744 | 9.445161910680917e-08 | KIRP |
| cg15120942 | chr3:38030087 | promoter | -0.178151064700689 | 1.25700965119926e-15 | -0.5436522982890485 | 1.500782623212705e-18 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of PLCD1 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000187091 | PLCD1 | C0029408 | Degenerative polyarthritis | 1 | CTD_human |
| ENSG00000187091 | PLCD1 | C0086743 | Osteoarthrosis Deformans | 1 | CTD_human |
| ENSG00000187091 | PLCD1 | C0544855 | NAIL DISORDER, NONSYNDROMIC CONGENITAL, 3 | 1 | CTD_human |
