|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
|
Gene: ENSG00000186912 |
Summary for P2RY4 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000186912 | Gene symbol | P2RY4 |
| Gene name | pyrimidinergic receptor P2Y4 | |
| HGNC | 8542 | |
| Entrez ID | 5030 | |
| Gene type | protein_coding | |
| Synonyms | P2RY4|NRU|P2Y4|UNR|P2P | |
| UniProtAcc | P51582 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for P2RY4 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for P2RY4 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for P2RY4 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg19545998 | chrX:70258515 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 7.56e-01 | 9.04e-01 | -4.15e+00 | 3.27e-05 | 6.73e-04 | -1.47e-01 |
| BRCA | cg04574723 | chrX:70259364 | CGI:chrX:70289794-70290112 | promoter,exon,CDS,gene body | 7.00e-01 | 9.04e-01 | -4.56e+00 | 5.04e-06 | 1.22e-04 | -2.04e-01 |
| BRCA | cg13172884 | chrX:70259757 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 7.09e-01 | 9.01e-01 | -4.88e+00 | 1.06e-06 | 2.99e-05 | -1.93e-01 |
| BRCA | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 7.06e-01 | 8.48e-01 | -4.05e+00 | 5.13e-05 | 1.00e-03 | -1.43e-01 |
| BRCA | cg03790146 | chrX:70260151 | CGI:chrX:70289794-70290112 | promoter | 7.06e-01 | 8.06e-01 | -2.24e+00 | 2.52e-02 | 3.82e-02 | -1.01e-01 |
| BRCA | cg26545968 | chrX:70260363 | CGI:chrX:70289794-70290112 | promoter | 7.54e-01 | 9.17e-01 | -4.40e+00 | 1.10e-05 | 2.49e-04 | -1.63e-01 |
| LUAD | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 7.12e-01 | 8.18e-01 | -1.23e+01 | 1.58e-34 | 3.27e-33 | -1.06e-01 |
| LGG | cg04574723 | chrX:70259364 | CGI:chrX:70289794-70290112 | promoter,exon,CDS,gene body | 7.39e-01 | 9.27e-01 | -1.93e+01 | 2.21e-83 | 5.70e-82 | -1.89e-01 |
| LGG | cg13172884 | chrX:70259757 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 6.49e-01 | 8.99e-01 | -1.94e+01 | 1.75e-83 | 4.54e-82 | -2.50e-01 |
| LGG | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 7.15e-01 | 9.00e-01 | -1.80e+01 | 4.53e-72 | 7.48e-71 | -1.85e-01 |
| LGG | cg03790146 | chrX:70260151 | CGI:chrX:70289794-70290112 | promoter | 7.47e-01 | 9.16e-01 | -1.56e+01 | 5.60e-55 | 6.55e-54 | -1.69e-01 |
| LGG | cg26545968 | chrX:70260363 | CGI:chrX:70289794-70290112 | promoter | 7.26e-01 | 9.24e-01 | -1.67e+01 | 8.13e-63 | 1.10e-61 | -1.98e-01 |
| HNSC | cg19545998 | chrX:70258515 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 7.73e-01 | 8.85e-01 | -1.34e+01 | 8.73e-41 | 2.08e-39 | -1.12e-01 |
| HNSC | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 6.58e-01 | 7.99e-01 | -1.25e+01 | 8.17e-36 | 1.80e-34 | -1.41e-01 |
| LUSC | cg19545998 | chrX:70258515 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 7.62e-01 | 8.82e-01 | -1.08e+01 | 4.14e-27 | 5.04e-26 | -1.20e-01 |
| LUSC | cg04574723 | chrX:70259364 | CGI:chrX:70289794-70290112 | promoter,exon,CDS,gene body | 6.96e-01 | 8.52e-01 | -1.12e+01 | 4.19e-29 | 5.29e-28 | -1.56e-01 |
| LUSC | cg13172884 | chrX:70259757 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 6.93e-01 | 8.69e-01 | -1.32e+01 | 7.54e-40 | 1.22e-38 | -1.76e-01 |
| LUSC | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 6.72e-01 | 8.05e-01 | -1.06e+01 | 3.16e-26 | 3.78e-25 | -1.32e-01 |
| LUSC | cg03790146 | chrX:70260151 | CGI:chrX:70289794-70290112 | promoter | 6.55e-01 | 7.73e-01 | -7.72e+00 | 1.20e-14 | 1.11e-13 | -1.18e-01 |
| LUSC | cg26545968 | chrX:70260363 | CGI:chrX:70289794-70290112 | promoter | 6.89e-01 | 8.42e-01 | -9.79e+00 | 1.18e-22 | 1.31e-21 | -1.52e-01 |
| SKCM | cg19545998 | chrX:70258515 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 7.01e-01 | 8.56e-01 | -1.15e+01 | 9.02e-31 | 8.85e-30 | -1.55e-01 |
| SKCM | cg04574723 | chrX:70259364 | CGI:chrX:70289794-70290112 | promoter,exon,CDS,gene body | 6.43e-01 | 8.01e-01 | -1.07e+01 | 1.46e-26 | 1.32e-25 | -1.59e-01 |
| SKCM | cg13172884 | chrX:70259757 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 6.58e-01 | 8.43e-01 | -1.42e+01 | 5.76e-46 | 7.81e-45 | -1.84e-01 |
| SKCM | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 6.24e-01 | 7.68e-01 | -1.06e+01 | 3.89e-26 | 3.46e-25 | -1.45e-01 |
| SKCM | cg03790146 | chrX:70260151 | CGI:chrX:70289794-70290112 | promoter | 5.92e-01 | 7.43e-01 | -9.74e+00 | 2.09e-22 | 1.70e-21 | -1.51e-01 |
| SKCM | cg26545968 | chrX:70260363 | CGI:chrX:70289794-70290112 | promoter | 6.57e-01 | 8.24e-01 | -1.08e+01 | 2.04e-27 | 1.88e-26 | -1.67e-01 |
| COAD | cg04574723 | chrX:70259364 | CGI:chrX:70289794-70290112 | promoter,exon,CDS,gene body | 7.67e-01 | 8.85e-01 | -1.21e+01 | 9.05e-34 | 1.42e-32 | -1.19e-01 |
| BLCA | cg19545998 | chrX:70258515 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 7.08e-01 | 8.18e-01 | -7.77e+00 | 7.90e-15 | 8.33e-14 | -1.10e-01 |
| STAD | cg04574723 | chrX:70259364 | CGI:chrX:70289794-70290112 | promoter,exon,CDS,gene body | 7.30e-01 | 8.47e-01 | -1.03e+01 | 7.63e-25 | 1.03e-23 | -1.17e-01 |
| STAD | cg13172884 | chrX:70259757 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 6.95e-01 | 8.38e-01 | -1.13e+01 | 9.92e-30 | 1.52e-28 | -1.43e-01 |
| STAD | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 6.76e-01 | 7.81e-01 | -8.58e+00 | 9.36e-18 | 9.91e-17 | -1.05e-01 |
| STAD | cg26545968 | chrX:70260363 | CGI:chrX:70289794-70290112 | promoter | 6.02e-01 | 7.43e-01 | -7.46e+00 | 8.46e-14 | 7.43e-13 | -1.41e-01 |
| LIHC | cg19545998 | chrX:70258515 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 6.27e-01 | 7.90e-01 | -8.06e+00 | 7.75e-16 | 1.78e-14 | -1.62e-01 |
| KIRP | cg03790146 | chrX:70260151 | CGI:chrX:70289794-70290112 | promoter | 7.52e-01 | 8.87e-01 | -8.02e+00 | 1.06e-15 | 1.64e-14 | -1.35e-01 |
| SARC | cg04574723 | chrX:70259364 | CGI:chrX:70289794-70290112 | promoter,exon,CDS,gene body | 7.31e-01 | 8.71e-01 | -9.55e+00 | 1.25e-21 | 1.87e-20 | -1.41e-01 |
| SARC | cg13172884 | chrX:70259757 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 7.02e-01 | 8.36e-01 | -9.52e+00 | 1.74e-21 | 2.58e-20 | -1.35e-01 |
| SARC | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 6.73e-01 | 7.79e-01 | -6.09e+00 | 1.14e-09 | 9.96e-09 | -1.06e-01 |
| SARC | cg03790146 | chrX:70260151 | CGI:chrX:70289794-70290112 | promoter | 7.27e-01 | 8.46e-01 | -7.07e+00 | 1.49e-12 | 1.49e-11 | -1.20e-01 |
| SARC | cg26545968 | chrX:70260363 | CGI:chrX:70289794-70290112 | promoter | 7.11e-01 | 8.62e-01 | -8.14e+00 | 3.79e-16 | 4.44e-15 | -1.51e-01 |
| PCPG | cg19545998 | chrX:70258515 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 7.18e-01 | 8.33e-01 | -6.50e+00 | 7.81e-11 | 4.46e-10 | -1.15e-01 |
| PCPG | cg04574723 | chrX:70259364 | CGI:chrX:70289794-70290112 | promoter,exon,CDS,gene body | 6.17e-01 | 7.97e-01 | -7.28e+00 | 3.35e-13 | 2.12e-12 | -1.81e-01 |
| PCPG | cg13172884 | chrX:70259757 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 6.75e-01 | 8.47e-01 | -9.15e+00 | 5.51e-20 | 5.27e-19 | -1.71e-01 |
| PCPG | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 6.62e-01 | 7.84e-01 | -6.18e+00 | 6.60e-10 | 3.62e-09 | -1.22e-01 |
| PCPG | cg03790146 | chrX:70260151 | CGI:chrX:70289794-70290112 | promoter | 5.82e-01 | 7.13e-01 | -4.95e+00 | 7.30e-07 | 3.50e-06 | -1.31e-01 |
| PCPG | cg26545968 | chrX:70260363 | CGI:chrX:70289794-70290112 | promoter | 5.52e-01 | 7.48e-01 | -6.01e+00 | 1.89e-09 | 1.02e-08 | -1.96e-01 |
| PAAD | cg04574723 | chrX:70259364 | CGI:chrX:70289794-70290112 | promoter,exon,CDS,gene body | 7.60e-01 | 8.85e-01 | -9.75e+00 | 1.91e-22 | 3.19e-21 | -1.25e-01 |
| PAAD | cg13172884 | chrX:70259757 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 7.27e-01 | 8.76e-01 | -1.11e+01 | 1.73e-28 | 4.22e-27 | -1.49e-01 |
| PAAD | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 7.22e-01 | 8.55e-01 | -1.07e+01 | 9.90e-27 | 2.07e-25 | -1.32e-01 |
| PAAD | cg03790146 | chrX:70260151 | CGI:chrX:70289794-70290112 | promoter | 7.12e-01 | 8.37e-01 | -7.98e+00 | 1.46e-15 | 1.64e-14 | -1.25e-01 |
| PAAD | cg26545968 | chrX:70260363 | CGI:chrX:70289794-70290112 | promoter | 7.25e-01 | 8.72e-01 | -9.57e+00 | 1.06e-21 | 1.72e-20 | -1.48e-01 |
| READ | cg04574723 | chrX:70259364 | CGI:chrX:70289794-70290112 | promoter,exon,CDS,gene body | 7.58e-01 | 8.59e-01 | -5.93e+00 | 3.06e-09 | 2.26e-08 | -1.01e-01 |
| READ | cg13172884 | chrX:70259757 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 7.06e-01 | 8.40e-01 | -6.19e+00 | 6.19e-10 | 4.89e-09 | -1.34e-01 |
| READ | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 6.43e-01 | 7.66e-01 | -5.04e+00 | 4.59e-07 | 2.79e-06 | -1.23e-01 |
| READ | cg26545968 | chrX:70260363 | CGI:chrX:70289794-70290112 | promoter | 3.69e-01 | 4.96e-01 | -3.35e+00 | 8.09e-04 | 3.28e-03 | -1.26e-01 |
| GBM | cg04574723 | chrX:70259364 | CGI:chrX:70289794-70290112 | promoter,exon,CDS,gene body | 7.30e-01 | 8.87e-01 | -5.39e+00 | 7.09e-08 | 5.51e-07 | -1.57e-01 |
| GBM | cg13172884 | chrX:70259757 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 6.63e-01 | 8.81e-01 | -5.94e+00 | 2.77e-09 | 2.56e-08 | -2.18e-01 |
| GBM | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 6.82e-01 | 8.51e-01 | -4.96e+00 | 7.11e-07 | 4.91e-06 | -1.69e-01 |
| GBM | cg03790146 | chrX:70260151 | CGI:chrX:70289794-70290112 | promoter | 6.72e-01 | 8.19e-01 | -3.42e+00 | 6.34e-04 | 2.68e-03 | -1.47e-01 |
| GBM | cg26545968 | chrX:70260363 | CGI:chrX:70289794-70290112 | promoter | 6.60e-01 | 8.67e-01 | -4.31e+00 | 1.67e-05 | 9.48e-05 | -2.07e-01 |
| ESCA | cg04574723 | chrX:70259364 | CGI:chrX:70289794-70290112 | promoter,exon,CDS,gene body | 7.09e-01 | 8.45e-01 | -5.66e+00 | 1.47e-08 | 1.16e-07 | -1.37e-01 |
| ESCA | cg13172884 | chrX:70259757 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 6.71e-01 | 8.48e-01 | -6.60e+00 | 4.23e-11 | 4.05e-10 | -1.77e-01 |
| ESCA | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 6.32e-01 | 7.88e-01 | -5.78e+00 | 7.68e-09 | 6.23e-08 | -1.56e-01 |
| ESCA | cg26545968 | chrX:70260363 | CGI:chrX:70289794-70290112 | promoter | 5.97e-01 | 7.71e-01 | -4.60e+00 | 4.23e-06 | 2.72e-05 | -1.74e-01 |
| LAML | cg13172884 | chrX:70259757 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 7.70e-01 | 9.04e-01 | -9.07e+00 | 1.20e-19 | 9.55e-19 | -1.34e-01 |
| THYM | cg04574723 | chrX:70259364 | CGI:chrX:70289794-70290112 | promoter,exon,CDS,gene body | 7.69e-01 | 9.23e-01 | -8.95e+00 | 3.47e-19 | 3.33e-18 | -1.54e-01 |
| THYM | cg13172884 | chrX:70259757 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 7.12e-01 | 8.98e-01 | -9.27e+00 | 1.83e-20 | 2.32e-19 | -1.86e-01 |
| THYM | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 7.63e-01 | 9.00e-01 | -9.08e+00 | 1.08e-19 | 1.13e-18 | -1.37e-01 |
| THYM | cg03790146 | chrX:70260151 | CGI:chrX:70289794-70290112 | promoter | 8.26e-01 | 9.28e-01 | -7.21e+00 | 5.68e-13 | 3.03e-12 | -1.02e-01 |
| THYM | cg26545968 | chrX:70260363 | CGI:chrX:70289794-70290112 | promoter | 8.18e-01 | 9.33e-01 | -7.91e+00 | 2.57e-15 | 1.63e-14 | -1.14e-01 |
| MESO | cg04574723 | chrX:70259364 | CGI:chrX:70289794-70290112 | promoter,exon,CDS,gene body | 7.68e-01 | 8.89e-01 | -5.21e+00 | 1.92e-07 | 1.70e-06 | -1.21e-01 |
| MESO | cg13172884 | chrX:70259757 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 7.31e-01 | 8.78e-01 | -5.20e+00 | 2.05e-07 | 1.80e-06 | -1.46e-01 |
| MESO | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 7.13e-01 | 8.43e-01 | -4.43e+00 | 9.31e-06 | 6.60e-05 | -1.30e-01 |
| MESO | cg26545968 | chrX:70260363 | CGI:chrX:70289794-70290112 | promoter | 7.83e-01 | 9.05e-01 | -4.89e+00 | 1.02e-06 | 8.14e-06 | -1.22e-01 |
| UVM | cg13172884 | chrX:70259757 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 7.34e-01 | 8.85e-01 | -6.65e+00 | 2.96e-11 | 2.51e-10 | -1.51e-01 |
| UVM | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 7.56e-01 | 8.71e-01 | -4.96e+00 | 7.02e-07 | 3.35e-06 | -1.15e-01 |
| ACC | cg03790146 | chrX:70260151 | CGI:chrX:70289794-70290112 | promoter | 7.08e-01 | 8.28e-01 | -3.44e+00 | 5.74e-04 | 3.29e-03 | -1.19e-01 |
| ACC | cg04574723 | chrX:70259364 | CGI:chrX:70289794-70290112 | promoter,exon,CDS,gene body | 7.21e-01 | 8.25e-01 | -4.39e+00 | 1.15e-05 | 8.66e-05 | -1.04e-01 |
| ACC | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 7.55e-01 | 8.69e-01 | -4.97e+00 | 6.70e-07 | 5.70e-06 | -1.15e-01 |
| ACC | cg13172884 | chrX:70259757 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 6.65e-01 | 8.91e-01 | -6.90e+00 | 5.29e-12 | 7.83e-11 | -2.26e-01 |
| ACC | cg19545998 | chrX:70258515 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 7.60e-01 | 8.72e-01 | -4.72e+00 | 2.37e-06 | 1.92e-05 | -1.11e-01 |
| ACC | cg26545968 | chrX:70260363 | CGI:chrX:70289794-70290112 | promoter | 7.00e-01 | 8.97e-01 | -5.34e+00 | 9.22e-08 | 8.47e-07 | -1.97e-01 |
| KICH | cg26545968 | chrX:70260363 | CGI:chrX:70289794-70290112 | promoter | 6.66e-01 | 8.04e-01 | -2.32e+00 | 2.05e-02 | 3.75e-02 | -1.38e-01 |
| DLBC | cg13172884 | chrX:70259757 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 6.32e-01 | 7.60e-01 | -2.94e+00 | 3.30e-03 | 9.79e-03 | -1.28e-01 |
| DLBC | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 6.18e-01 | 7.51e-01 | -3.10e+00 | 1.91e-03 | 6.26e-03 | -1.33e-01 |
| DLBC | cg26545968 | chrX:70260363 | CGI:chrX:70289794-70290112 | promoter | 6.41e-01 | 7.96e-01 | -2.94e+00 | 3.30e-03 | 9.79e-03 | -1.55e-01 |
| CHOL | cg19545998 | chrX:70258515 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 7.38e-01 | 8.40e-01 | -3.25e+00 | 1.17e-03 | 4.25e-03 | -1.02e-01 |
| CHOL | cg04574723 | chrX:70259364 | CGI:chrX:70289794-70290112 | promoter,exon,CDS,gene body | 7.46e-01 | 8.85e-01 | -4.27e+00 | 1.99e-05 | 1.22e-04 | -1.39e-01 |
| CHOL | cg13172884 | chrX:70259757 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 6.87e-01 | 8.52e-01 | -4.04e+00 | 5.27e-05 | 2.87e-04 | -1.65e-01 |
| CHOL | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 7.04e-01 | 8.77e-01 | -4.43e+00 | 9.64e-06 | 6.48e-05 | -1.73e-01 |
| CHOL | cg03790146 | chrX:70260151 | CGI:chrX:70289794-70290112 | promoter | 6.94e-01 | 8.25e-01 | -2.93e+00 | 3.40e-03 | 9.59e-03 | -1.32e-01 |
| CHOL | cg26545968 | chrX:70260363 | CGI:chrX:70289794-70290112 | promoter | 7.18e-01 | 8.92e-01 | -3.85e+00 | 1.17e-04 | 5.93e-04 | -1.74e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| THCA | cg03790146 | chrX:70260151 | CGI:chrX:70289794-70290112 | promoter | 6.63e-01 | 7.88e-01 | -2.95e+00 | 3.19e-03 | 7.26e-03 | -1.25e-01 |
| HNSC | cg03790146 | chrX:70260151 | CGI:chrX:70289794-70290112 | promoter | 7.82e-01 | 8.85e-01 | -3.34e+00 | 8.36e-04 | 1.56e-03 | -1.03e-01 |
| LUSC | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 8.05e-01 | 9.11e-01 | -4.24e+00 | 2.24e-05 | 5.26e-04 | -1.06e-01 |
| KIRP | cg03790146 | chrX:70260151 | CGI:chrX:70289794-70290112 | promoter | 8.87e-01 | 7.54e-01 | 5.29e+00 | 1.24e-07 | 1.00e-06 | 1.33e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg19545998 | chrX:70258515 | CGI:chrX:70289794-70290112 | UTR,promoter,exon,gene body | 7.56e-01 | 8.69e-01 | -8.42e+00 | 3.63e-17 | 1.56e-16 | -1.13e-01 |
| HNSC | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 6.58e-01 | 7.84e-01 | -2.91e+00 | 3.65e-03 | 1.18e-02 | -1.26e-01 |
| BLCA | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 6.42e-01 | 7.42e-01 | -2.65e+00 | 8.15e-03 | 1.53e-02 | -1.00e-01 |
| BLCA | cg26545968 | chrX:70260363 | CGI:chrX:70289794-70290112 | promoter | 6.41e-01 | 7.61e-01 | -2.17e+00 | 3.00e-02 | 3.54e-02 | -1.21e-01 |
| LIHC | cg11085564 | chrX:70259989 | CGI:chrX:70289794-70290112 | promoter | 6.33e-01 | 7.74e-01 | -4.25e+00 | 2.17e-05 | 1.22e-04 | -1.40e-01 |
Top |
Exon skipping events with PSI in TCGA for P2RY4 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for P2RY4 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for P2RY4 |
| TFs related to P2RY4. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| CHOL | HKR1 | P2RY4 | 3.95e+00 | 9.85e-01 | 2.67e+00 | 2.75e-03 | Male-biased |
| CHOL | ZNF283 | P2RY4 | 3.88e+00 | 9.85e-01 | 2.28e+00 | 6.86e-04 | Male-biased |
| CHOL | ZNF467 | P2RY4 | 3.79e+00 | 9.80e-01 | 2.54e+00 | 3.08e-03 | Male-biased |
| CHOL | ZNF529 | P2RY4 | 3.93e+00 | 9.85e-01 | 2.58e+00 | 1.95e-03 | Male-biased |
| GBM | BARX1 | P2RY4 | 4.41e+00 | 1.61e-02 | 5.31e+00 | 9.82e-01 | Female-biased |
| GBM | HKR1 | P2RY4 | 4.78e+00 | 9.95e-01 | 3.02e+00 | 1.22e-03 | Male-biased |
| GBM | NKX3-1 | P2RY4 | 4.44e+00 | 1.61e-02 | 5.33e+00 | 9.82e-01 | Female-biased |
| GBM | SPZ1 | P2RY4 | 4.93e+00 | 9.96e-01 | 3.14e+00 | 1.08e-03 | Male-biased |
| GBM | ZBTB6 | P2RY4 | 5.17e+00 | 9.91e-01 | 3.95e+00 | 7.06e-03 | Male-biased |
| GBM | ZIM2 | P2RY4 | 4.79e+00 | 9.95e-01 | 2.83e+00 | 5.73e-04 | Male-biased |
| GBM | ZKSCAN1 | P2RY4 | 4.73e+00 | 9.83e-01 | 3.71e+00 | 1.26e-02 | Male-biased |
| GBM | ZNF132 | P2RY4 | 4.79e+00 | 9.94e-01 | 3.22e+00 | 2.37e-03 | Male-biased |
| GBM | ZNF281 | P2RY4 | 4.61e+00 | 9.94e-01 | 2.84e+00 | 1.14e-03 | Male-biased |
| GBM | ZNF283 | P2RY4 | 4.81e+00 | 9.94e-01 | 3.14e+00 | 1.67e-03 | Male-biased |
| GBM | ZNF324B | P2RY4 | 4.90e+00 | 9.91e-01 | 3.62e+00 | 5.87e-03 | Male-biased |
| GBM | ZNF343 | P2RY4 | 4.95e+00 | 9.91e-01 | 3.67e+00 | 5.80e-03 | Male-biased |
| GBM | ZNF35 | P2RY4 | 3.92e+00 | 6.24e-03 | 5.18e+00 | 9.92e-01 | Female-biased |
| GBM | ZNF37A | P2RY4 | 4.74e+00 | 9.94e-01 | 2.98e+00 | 1.22e-03 | Male-biased |
| GBM | ZNF415 | P2RY4 | 5.02e+00 | 9.97e-01 | 3.08e+00 | 6.30e-04 | Male-biased |
| GBM | ZNF529 | P2RY4 | 4.52e+00 | 9.90e-01 | 3.07e+00 | 3.30e-03 | Male-biased |
| GBM | ZNF554 | P2RY4 | 5.25e+00 | 9.97e-01 | 3.27e+00 | 5.70e-04 | Male-biased |
| GBM | ZNF582 | P2RY4 | 4.79e+00 | 9.89e-01 | 3.56e+00 | 6.55e-03 | Male-biased |
| GBM | ZNF692 | P2RY4 | 5.25e+00 | 9.98e-01 | 3.06e+00 | 2.44e-04 | Male-biased |
| GBM | ZNF768 | P2RY4 | 4.57e+00 | 9.93e-01 | 2.91e+00 | 1.68e-03 | Male-biased |
| GBM | ZNF84 | P2RY4 | 4.45e+00 | 9.80e-01 | 3.42e+00 | 1.24e-02 | Male-biased |
| PAAD | NKX3-1 | P2RY4 | 4.79e+00 | 1.78e-02 | 5.48e+00 | 9.81e-01 | Female-biased |
| PAAD | ZNF35 | P2RY4 | 4.32e+00 | 1.33e-02 | 5.07e+00 | 9.84e-01 | Female-biased |
| P2RY4 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for P2RY4 |
| RBPs related to ES in P2RY4. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| P2RY4 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of P2RY4 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
