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Gene: ENSG00000186810 |
Summary for CXCR3 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000186810 | Gene symbol | CXCR3 |
| Gene name | C-X-C motif chemokine receptor 3 | |
| HGNC | 4540 | |
| Entrez ID | 2833 | |
| Gene type | protein_coding | |
| Synonyms | CXCR3|CKR-L2|CMKAR3|IP10-R|MigR|CD183 | |
| UniProtAcc | P49682 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for CXCR3 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| CXCR3 | 2.45e+02 | -1.21e+00 | 3.29e-01 | -3.67e+00 | 2.39e-04 | 2.71e-02 | ESCA |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| CXCR3 | 7.96e+01 | 1.29e+00 | 3.48e-01 | 3.71e+00 | 2.05e-04 | 6.16e-04 | LIHC |
| CXCR3 | 2.78e+02 | 1.63e+00 | 1.53e-01 | 1.06e+01 | 2.90e-26 | 1.27e-25 | BRCA |
| CXCR3 | 2.76e+02 | 1.50e+00 | 4.05e-01 | 3.71e+00 | 2.07e-04 | 8.96e-04 | READ |
Top |
Sex-biased somatic mutation for CXCR3 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for CXCR3 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg08843314 | chrX:71618140 | CGI:chrX:71603663-71604253 | promoter,gene body | 7.49e-01 | 9.40e-01 | -4.64e+00 | 3.49e-06 | 8.74e-05 | -1.91e-01 |
| BRCA | cg17678039 | chrX:71618626 | CGI:chrX:71603663-71604253 | promoter | 6.03e-01 | 7.38e-01 | -3.11e+00 | 1.86e-03 | 1.32e-02 | -1.35e-01 |
| BRCA | cg12875534 | chrX:71619379 | CGI:chrX:71603663-71604253 | promoter | 7.05e-01 | 8.71e-01 | -4.06e+00 | 4.94e-05 | 9.69e-04 | -1.66e-01 |
| BRCA | cg07182248 | chrX:71619434 | CGI:chrX:71603663-71604253 | promoter | 7.22e-01 | 8.89e-01 | -3.90e+00 | 9.72e-05 | 1.64e-03 | -1.66e-01 |
| LGG | cg08843314 | chrX:71618140 | CGI:chrX:71603663-71604253 | promoter,gene body | 7.95e-01 | 9.54e-01 | -1.85e+01 | 1.32e-76 | 2.49e-75 | -1.58e-01 |
| LGG | cg17678039 | chrX:71618626 | CGI:chrX:71603663-71604253 | promoter | 6.92e-01 | 8.38e-01 | -1.31e+01 | 2.15e-39 | 1.96e-38 | -1.46e-01 |
| LGG | cg12875534 | chrX:71619379 | CGI:chrX:71603663-71604253 | promoter | 7.40e-01 | 9.13e-01 | -1.66e+01 | 1.48e-61 | 1.94e-60 | -1.72e-01 |
| THCA | cg12875534 | chrX:71619379 | CGI:chrX:71603663-71604253 | promoter | 6.28e-01 | 5.25e-01 | 4.75e+00 | 2.01e-06 | 9.03e-06 | 1.03e-01 |
| THCA | cg12493424 | chrX:71619383 | CGI:chrX:71603663-71604253 | promoter | 7.74e-01 | 6.20e-01 | 3.26e+00 | 1.10e-03 | 3.81e-03 | 1.54e-01 |
| THCA | cg07182248 | chrX:71619434 | CGI:chrX:71603663-71604253 | promoter | 6.79e-01 | 4.76e-01 | 7.34e+00 | 2.09e-13 | 1.22e-12 | 2.03e-01 |
| HNSC | cg08843314 | chrX:71618140 | CGI:chrX:71603663-71604253 | promoter,gene body | 7.41e-01 | 8.58e-01 | -1.12e+01 | 4.25e-29 | 8.36e-28 | -1.17e-01 |
| LUSC | cg08843314 | chrX:71618140 | CGI:chrX:71603663-71604253 | promoter,gene body | 7.35e-01 | 8.63e-01 | -9.43e+00 | 4.10e-21 | 4.37e-20 | -1.28e-01 |
| SKCM | cg05356800 | chrX:71616972 | CGI:chrX:71603663-71604253 | promoter,exon,CDS,gene body | 7.99e-01 | 9.12e-01 | -8.44e+00 | 3.18e-17 | 2.30e-16 | -1.14e-01 |
| SKCM | cg08843314 | chrX:71618140 | CGI:chrX:71603663-71604253 | promoter,gene body | 7.20e-01 | 8.70e-01 | -1.05e+01 | 5.63e-26 | 5.00e-25 | -1.50e-01 |
| SKCM | cg12875534 | chrX:71619379 | CGI:chrX:71603663-71604253 | promoter | 6.47e-01 | 7.59e-01 | -8.12e+00 | 4.63e-16 | 3.26e-15 | -1.12e-01 |
| COAD | cg05356800 | chrX:71616972 | CGI:chrX:71603663-71604253 | promoter,exon,CDS,gene body | 7.09e-01 | 5.47e-01 | 5.02e+00 | 5.25e-07 | 3.80e-06 | 1.62e-01 |
| LIHC | cg08843314 | chrX:71618140 | CGI:chrX:71603663-71604253 | promoter,gene body | 7.29e-01 | 9.02e-01 | -1.15e+01 | 1.64e-30 | 5.53e-29 | -1.73e-01 |
| LIHC | cg12875534 | chrX:71619379 | CGI:chrX:71603663-71604253 | promoter | 7.20e-01 | 8.68e-01 | -1.01e+01 | 7.18e-24 | 2.09e-22 | -1.48e-01 |
| LIHC | cg07182248 | chrX:71619434 | CGI:chrX:71603663-71604253 | promoter | 7.28e-01 | 8.78e-01 | -8.85e+00 | 8.88e-19 | 2.25e-17 | -1.51e-01 |
| PCPG | cg08843314 | chrX:71618140 | CGI:chrX:71603663-71604253 | promoter,gene body | 8.03e-01 | 9.38e-01 | -9.56e+00 | 1.14e-21 | 1.21e-20 | -1.35e-01 |
| PCPG | cg17678039 | chrX:71618626 | CGI:chrX:71603663-71604253 | promoter | 7.04e-01 | 8.24e-01 | -6.41e+00 | 1.42e-10 | 7.99e-10 | -1.20e-01 |
| PCPG | cg12875534 | chrX:71619379 | CGI:chrX:71603663-71604253 | promoter | 6.21e-01 | 7.31e-01 | -4.59e+00 | 4.41e-06 | 2.04e-05 | -1.09e-01 |
| PCPG | cg07182248 | chrX:71619434 | CGI:chrX:71603663-71604253 | promoter | 7.22e-01 | 8.28e-01 | -4.75e+00 | 2.05e-06 | 9.64e-06 | -1.06e-01 |
| PAAD | cg06623468 | chrX:71618180 | CGI:chrX:71603663-71604253 | promoter,gene body | 3.98e-01 | 2.29e-01 | 9.91e+00 | 3.87e-23 | 6.67e-22 | 1.69e-01 |
| READ | cg05356800 | chrX:71616972 | CGI:chrX:71603663-71604253 | promoter,exon,CDS,gene body | 6.58e-01 | 5.00e-01 | 3.41e+00 | 6.57e-04 | 2.72e-03 | 1.58e-01 |
| READ | cg06623468 | chrX:71618180 | CGI:chrX:71603663-71604253 | promoter,gene body | 2.91e-01 | 1.63e-01 | 6.29e+00 | 3.27e-10 | 2.65e-09 | 1.28e-01 |
| READ | cg07182248 | chrX:71619434 | CGI:chrX:71603663-71604253 | promoter | 6.45e-01 | 5.32e-01 | 2.84e+00 | 4.47e-03 | 1.41e-02 | 1.13e-01 |
| GBM | cg05356800 | chrX:71616972 | CGI:chrX:71603663-71604253 | promoter,exon,CDS,gene body | 8.20e-01 | 9.68e-01 | -5.04e+00 | 4.61e-07 | 3.26e-06 | -1.49e-01 |
| GBM | cg08843314 | chrX:71618140 | CGI:chrX:71603663-71604253 | promoter,gene body | 7.38e-01 | 9.42e-01 | -6.25e+00 | 4.10e-10 | 4.36e-09 | -2.04e-01 |
| GBM | cg12875534 | chrX:71619379 | CGI:chrX:71603663-71604253 | promoter | 6.52e-01 | 7.63e-01 | -3.47e+00 | 5.16e-04 | 2.22e-03 | -1.11e-01 |
| ESCA | cg08843314 | chrX:71618140 | CGI:chrX:71603663-71604253 | promoter,gene body | 7.30e-01 | 8.82e-01 | -5.16e+00 | 2.52e-07 | 1.81e-06 | -1.52e-01 |
| ESCA | cg17678039 | chrX:71618626 | CGI:chrX:71603663-71604253 | promoter | 5.10e-01 | 6.22e-01 | -3.52e+00 | 4.40e-04 | 2.14e-03 | -1.12e-01 |
| LAML | cg06623468 | chrX:71618180 | CGI:chrX:71603663-71604253 | promoter,gene body | 3.45e-01 | 1.14e-01 | 8.31e+00 | 9.80e-17 | 6.42e-16 | 2.31e-01 |
| LAML | cg12875534 | chrX:71619379 | CGI:chrX:71603663-71604253 | promoter | 5.35e-01 | 2.89e-01 | 5.86e+00 | 4.52e-09 | 1.90e-08 | 2.46e-01 |
| LAML | cg12493424 | chrX:71619383 | CGI:chrX:71603663-71604253 | promoter | 6.77e-01 | 4.37e-01 | 3.95e+00 | 7.89e-05 | 2.64e-04 | 2.40e-01 |
| LAML | cg07182248 | chrX:71619434 | CGI:chrX:71603663-71604253 | promoter | 6.21e-01 | 3.98e-01 | 4.14e+00 | 3.53e-05 | 1.21e-04 | 2.24e-01 |
| THYM | cg06623468 | chrX:71618180 | CGI:chrX:71603663-71604253 | promoter,gene body | 4.02e-01 | 2.08e-01 | 8.13e+00 | 4.17e-16 | 2.84e-15 | 1.94e-01 |
| ACC | cg05356800 | chrX:71616972 | CGI:chrX:71603663-71604253 | promoter,exon,CDS,gene body | 8.64e-01 | 9.64e-01 | -4.00e+00 | 6.44e-05 | 4.47e-04 | -1.00e-01 |
| ACC | cg07182248 | chrX:71619434 | CGI:chrX:71603663-71604253 | promoter | 8.17e-01 | 9.28e-01 | -3.62e+00 | 2.89e-04 | 1.79e-03 | -1.11e-01 |
| ACC | cg08843314 | chrX:71618140 | CGI:chrX:71603663-71604253 | promoter,gene body | 7.69e-01 | 9.03e-01 | -4.66e+00 | 3.18e-06 | 2.55e-05 | -1.33e-01 |
| ACC | cg12875534 | chrX:71619379 | CGI:chrX:71603663-71604253 | promoter | 7.41e-01 | 8.95e-01 | -5.13e+00 | 2.89e-07 | 2.54e-06 | -1.54e-01 |
| ACC | cg17678039 | chrX:71618626 | CGI:chrX:71603663-71604253 | promoter | 6.42e-01 | 7.80e-01 | -4.03e+00 | 5.67e-05 | 3.96e-04 | -1.38e-01 |
| DLBC | cg08843314 | chrX:71618140 | CGI:chrX:71603663-71604253 | promoter,gene body | 4.98e-01 | 3.81e-01 | 2.01e+00 | 4.47e-02 | 4.83e-02 | 1.17e-01 |
| DLBC | cg06623468 | chrX:71618180 | CGI:chrX:71603663-71604253 | promoter,gene body | 2.99e-01 | 1.12e-01 | 5.28e+00 | 1.32e-07 | 1.25e-06 | 1.87e-01 |
| DLBC | cg12875534 | chrX:71619379 | CGI:chrX:71603663-71604253 | promoter | 3.39e-01 | 2.16e-01 | 3.27e+00 | 1.08e-03 | 3.81e-03 | 1.23e-01 |
| DLBC | cg12493424 | chrX:71619383 | CGI:chrX:71603663-71604253 | promoter | 4.39e-01 | 2.96e-01 | 2.28e+00 | 2.28e-02 | 3.74e-02 | 1.43e-01 |
| DLBC | cg07182248 | chrX:71619434 | CGI:chrX:71603663-71604253 | promoter | 3.62e-01 | 2.29e-01 | 3.25e+00 | 1.16e-03 | 4.06e-03 | 1.34e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg05356800 | chrX:71616972 | CGI:chrX:71603663-71604253 | promoter,exon,CDS,gene body | 8.27e-01 | 9.50e-01 | -4.95e+00 | 7.37e-07 | 2.79e-06 | -1.23e-01 |
| KIRC | cg08843314 | chrX:71618140 | CGI:chrX:71603663-71604253 | promoter,gene body | 8.01e-01 | 9.37e-01 | -5.21e+00 | 1.89e-07 | 8.61e-07 | -1.36e-01 |
| THCA | cg17678039 | chrX:71618626 | CGI:chrX:71603663-71604253 | promoter | 2.54e-01 | 3.83e-01 | -4.10e+00 | 4.12e-05 | 3.22e-04 | -1.29e-01 |
| LUSC | cg17678039 | chrX:71618626 | CGI:chrX:71603663-71604253 | promoter | 5.52e-01 | 4.32e-01 | 2.36e+00 | 1.83e-02 | 2.22e-02 | 1.20e-01 |
| LUSC | cg12875534 | chrX:71619379 | CGI:chrX:71603663-71604253 | promoter | 6.99e-01 | 8.35e-01 | -3.00e+00 | 2.74e-03 | 5.24e-03 | -1.36e-01 |
| LUSC | cg07182248 | chrX:71619434 | CGI:chrX:71603663-71604253 | promoter | 7.06e-01 | 8.93e-01 | -3.44e+00 | 5.75e-04 | 1.81e-03 | -1.88e-01 |
| COAD | cg05356800 | chrX:71616972 | CGI:chrX:71603663-71604253 | promoter,exon,CDS,gene body | 5.47e-01 | 8.65e-01 | -3.20e+00 | 1.35e-03 | 2.87e-03 | -3.18e-01 |
| COAD | cg08843314 | chrX:71618140 | CGI:chrX:71603663-71604253 | promoter,gene body | 7.50e-01 | 8.87e-01 | -2.56e+00 | 1.05e-02 | 1.49e-02 | -1.37e-01 |
| COAD | cg17678039 | chrX:71618626 | CGI:chrX:71603663-71604253 | promoter | 5.07e-01 | 6.61e-01 | -3.53e+00 | 4.14e-04 | 1.10e-03 | -1.54e-01 |
| BLCA | cg07182248 | chrX:71619434 | CGI:chrX:71603663-71604253 | promoter | 7.39e-01 | 8.74e-01 | -2.78e+00 | 5.42e-03 | 8.68e-03 | -1.34e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg08843314 | chrX:71618140 | CGI:chrX:71603663-71604253 | promoter,gene body | 7.49e-01 | 8.90e-01 | -1.02e+01 | 1.37e-24 | 1.12e-23 | -1.42e-01 |
| BRCA | cg17678039 | chrX:71618626 | CGI:chrX:71603663-71604253 | promoter | 6.03e-01 | 7.11e-01 | -7.47e+00 | 8.02e-14 | 2.68e-13 | -1.07e-01 |
| LUAD | cg08843314 | chrX:71618140 | CGI:chrX:71603663-71604253 | promoter,gene body | 7.19e-01 | 8.45e-01 | -3.16e+00 | 1.60e-03 | 4.37e-03 | -1.26e-01 |
| LUAD | cg17678039 | chrX:71618626 | CGI:chrX:71603663-71604253 | promoter | 4.13e-01 | 5.61e-01 | -3.34e+00 | 8.23e-04 | 2.81e-03 | -1.48e-01 |
| LUAD | cg12875534 | chrX:71619379 | CGI:chrX:71603663-71604253 | promoter | 6.99e-01 | 8.17e-01 | -2.93e+00 | 3.36e-03 | 7.29e-03 | -1.18e-01 |
| HNSC | cg08843314 | chrX:71618140 | CGI:chrX:71603663-71604253 | promoter,gene body | 7.41e-01 | 8.52e-01 | -2.54e+00 | 1.09e-02 | 1.95e-02 | -1.11e-01 |
| HNSC | cg12493424 | chrX:71619383 | CGI:chrX:71603663-71604253 | promoter | 7.79e-01 | 9.12e-01 | -3.03e+00 | 2.44e-03 | 1.03e-02 | -1.33e-01 |
| LIHC | cg05356800 | chrX:71616972 | CGI:chrX:71603663-71604253 | promoter,exon,CDS,gene body | 8.10e-01 | 9.29e-01 | -2.80e+00 | 5.14e-03 | 8.21e-03 | -1.19e-01 |
| LIHC | cg07182248 | chrX:71619434 | CGI:chrX:71603663-71604253 | promoter | 7.28e-01 | 8.74e-01 | -3.49e+00 | 4.87e-04 | 1.29e-03 | -1.46e-01 |
Top |
Exon skipping events with PSI in TCGA for CXCR3 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for CXCR3 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for CXCR3 |
| TFs related to CXCR3. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| BRCA | ELF5 | CXCR3 | 3.46e+00 | 4.56e-03 | 4.93e+00 | 9.91e-01 | Female-biased |
| BRCA | HIC1 | CXCR3 | 4.34e+00 | 8.45e-03 | 5.62e+00 | 9.90e-01 | Female-biased |
| BRCA | INSM1 | CXCR3 | 3.43e+00 | 2.00e-03 | 5.17e+00 | 9.95e-01 | Female-biased |
| BRCA | PATZ1 | CXCR3 | 3.11e+00 | 6.36e-04 | 5.20e+00 | 9.96e-01 | Female-biased |
| BRCA | TFAP4 | CXCR3 | 3.75e+00 | 3.96e-03 | 5.27e+00 | 9.93e-01 | Female-biased |
| BRCA | ZNF121 | CXCR3 | 4.09e+00 | 9.81e-01 | 2.59e+00 | 4.29e-03 | Male-biased |
| BRCA | ZNF257 | CXCR3 | 3.76e+00 | 9.33e-03 | 5.00e+00 | 9.86e-01 | Female-biased |
| BRCA | ZNF281 | CXCR3 | 2.99e+00 | 2.09e-03 | 4.70e+00 | 9.91e-01 | Female-biased |
| BRCA | ZNF324B | CXCR3 | 4.02e+00 | 9.40e-03 | 5.26e+00 | 9.88e-01 | Female-biased |
| BRCA | ZNF333 | CXCR3 | 4.05e+00 | 6.19e-03 | 5.42e+00 | 9.92e-01 | Female-biased |
| BRCA | ZNF335 | CXCR3 | 3.37e+00 | 2.27e-03 | 5.07e+00 | 9.94e-01 | Female-biased |
| BRCA | ZNF436 | CXCR3 | 3.45e+00 | 2.43e-03 | 5.13e+00 | 9.94e-01 | Female-biased |
| BRCA | ZNF44 | CXCR3 | 2.71e+00 | 2.16e-03 | 4.40e+00 | 9.86e-01 | Female-biased |
| BRCA | ZNF443 | CXCR3 | 4.26e+00 | 9.86e-01 | 2.63e+00 | 2.93e-03 | Male-biased |
| BRCA | ZNF527 | CXCR3 | 3.29e+00 | 7.32e-03 | 4.60e+00 | 9.84e-01 | Female-biased |
| BRCA | ZNF530 | CXCR3 | 3.21e+00 | 1.48e-03 | 5.04e+00 | 9.95e-01 | Female-biased |
| BRCA | ZNF549 | CXCR3 | 4.12e+00 | 7.90e-03 | 5.42e+00 | 9.90e-01 | Female-biased |
| BRCA | ZNF552 | CXCR3 | 4.57e+00 | 1.50e-02 | 5.66e+00 | 9.83e-01 | Female-biased |
| BRCA | ZNF554 | CXCR3 | 3.54e+00 | 6.39e-03 | 4.90e+00 | 9.89e-01 | Female-biased |
| BRCA | ZNF611 | CXCR3 | 2.45e+00 | 4.39e-04 | 4.64e+00 | 9.92e-01 | Female-biased |
| BRCA | ZNF860 | CXCR3 | 3.23e+00 | 9.91e-04 | 5.19e+00 | 9.96e-01 | Female-biased |
| BRCA | ZNF891 | CXCR3 | 3.27e+00 | 9.37e-04 | 5.25e+00 | 9.96e-01 | Female-biased |
| CHOL | ELF4 | CXCR3 | 4.22e+00 | 1.15e-02 | 5.12e+00 | 9.86e-01 | Female-biased |
| CHOL | ZNF121 | CXCR3 | 2.41e+00 | 1.30e-04 | 4.32e+00 | 9.92e-01 | Female-biased |
| CHOL | ZNF181 | CXCR3 | 2.56e+00 | 1.77e-04 | 4.40e+00 | 9.93e-01 | Female-biased |
| CHOL | ZNF33A | CXCR3 | 2.49e+00 | 9.78e-05 | 4.45e+00 | 9.94e-01 | Female-biased |
| CHOL | ZNF443 | CXCR3 | 2.65e+00 | 2.30e-04 | 4.44e+00 | 9.94e-01 | Female-biased |
| CHOL | ZNF496 | CXCR3 | 2.48e+00 | 2.31e-04 | 4.27e+00 | 9.92e-01 | Female-biased |
| CHOL | ZNF554 | CXCR3 | 3.24e+00 | 5.29e-03 | 4.33e+00 | 9.87e-01 | Female-biased |
| CHOL | ZNF627 | CXCR3 | 5.51e+00 | 9.84e-01 | 4.63e+00 | 1.47e-02 | Male-biased |
| CHOL | ZNF770 | CXCR3 | 2.14e+00 | 3.25e-04 | 3.85e+00 | 9.84e-01 | Female-biased |
| CHOL | ZNF787 | CXCR3 | 2.88e+00 | 3.31e-03 | 4.08e+00 | 9.86e-01 | Female-biased |
| DLBC | ZNF333 | CXCR3 | 4.74e+00 | 9.82e-01 | 3.94e+00 | 1.27e-02 | Male-biased |
| SARC | BCL11A | CXCR3 | 3.73e+00 | 1.02e-02 | 4.37e+00 | 9.82e-01 | Female-biased |
| SARC | ZBTB33 | CXCR3 | 6.23e+00 | 1.60e-02 | 6.79e+00 | 9.84e-01 | Female-biased |
| SARC | ZNF620 | CXCR3 | 3.99e+00 | 1.26e-02 | 4.59e+00 | 9.82e-01 | Female-biased |
| CXCR3 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for CXCR3 |
| RBPs related to ES in CXCR3. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| CXCR3 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000186810 |
| CpG Site: cg06623468 | |
| Position to Gene: gene,promoter | |
| Male Effect: -0.061561448003251 | |
| Female Effect: - | |
 | Gene ID: ENSG00000186810 |
| CpG Site: cg17678039 | |
| Position to Gene: promoter | |
| Male Effect: -0.221435785006661 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg06623468 | chrX:71618180 | gene,promoter | -0.061561448003251 | 8.62629309686483e-05 | -0.34151566326075045 | 1.701244820690465e-07 | LUAD |
| cg17678039 | chrX:71618626 | promoter | -0.221435785006661 | 1.15810584764593e-05 | -0.33050039386299923 | 7.328632656341728e-08 | LIHC |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of CXCR3 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000186810 | CXCR3 | C0002171 | Alopecia Areata | 1 | CTD_human |
| ENSG00000186810 | CXCR3 | C0004364 | Autoimmune Diseases | 1 | CTD_human |
| ENSG00000186810 | CXCR3 | C0011615 | Dermatitis, Atopic | 1 | CTD_human |
| ENSG00000186810 | CXCR3 | C0011616 | Contact Dermatitis | 1 | CTD_human |
| ENSG00000186810 | CXCR3 | C0017658 | Glomerulonephritis | 1 | CTD_human |
| ENSG00000186810 | CXCR3 | C0020517 | Hypersensitivity | 1 | CTD_human |
| ENSG00000186810 | CXCR3 | C0021368 | Inflammation | 1 | CTD_human |
| ENSG00000186810 | CXCR3 | C0022116 | Ischemia | 1 | CTD_human |
| ENSG00000186810 | CXCR3 | C0032226 | Pleural Diseases | 1 | CTD_human |
| ENSG00000186810 | CXCR3 | C0032285 | Pneumonia | 1 | CTD_human |
| ENSG00000186810 | CXCR3 | C0032300 | Lobar Pneumonia | 1 | CTD_human |
| ENSG00000186810 | CXCR3 | C0038454 | Cerebrovascular accident | 1 | CTD_human |
| ENSG00000186810 | CXCR3 | C0086196 | Eczema, Infantile | 1 | CTD_human |
| ENSG00000186810 | CXCR3 | C0162351 | Contact hypersensitivity | 1 | CTD_human |
| ENSG00000186810 | CXCR3 | C0751956 | Acute Cerebrovascular Accidents | 1 | CTD_human |
| ENSG00000186810 | CXCR3 | C0887898 | Experimental Lung Inflammation | 1 | CTD_human |
| ENSG00000186810 | CXCR3 | C1527304 | Allergic Reaction | 1 | CTD_human |
| ENSG00000186810 | CXCR3 | C1704377 | Bright Disease | 1 | CTD_human |
| ENSG00000186810 | CXCR3 | C3714636 | Pneumonitis | 1 | CTD_human |
