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Gene: ENSG00000184937

Summary for WT1

Gene summary

Gene information	Ensembl ID	ENSG00000184937
	Gene symbol	WT1
	Gene name	WT1 transcription factor
	HGNC	12796
	Entrez ID	7490
	Gene type	protein_coding
	Synonyms	WT1\|WAGR\|WIT-2\|AWT1\|NPHS4\|WT-1
	UniProtAcc	P19544

Drugs associated with this gene(DrugBank).

Gene ID

Gene Symbol

Drug ID

Drug Name

Drug Type

Cancer therapeutic drugs associated with this gene(NCI).

Gene ID

Gene Name

Drug ID

Drug Name

Drug Type

Cancer

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Structure and expression level for WT1

AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure.
∗For more information on exon skipping events please check the ExonskipDB database.
∗For more information on exon skipping events please check the CAeditome database.

Landscape of gene expressions across multiple cancer types.

Differentially expressed gene analysis between tumor male and tumor female samples.

Coding Name	Base Mean	log2FoldChange	lfcSE	Stat	P value	P.adjust Value	Cancer Type
WT1	3.34e+02	-4.66e+00	7.52e-01	-6.20e+00	5.57e-10	1.70e-07	BRCA

Differentially expressed gene analysis between tumor male and normal male samples.

Coding Name

Base Mean

log2FoldChange

lfcSE

Stat

P value

P.adjust Value

Cancer Type

Differentially expressed gene analysis between tumor female and normal female samples.

Coding Name	Base Mean	log2FoldChange	lfcSE	Stat	P value	P.adjust Value	Cancer Type
WT1	2.03e+02	-4.70e+00	8.48e-01	-5.54e+00	2.99e-08	8.25e-07	KIRP
WT1	3.07e+02	4.74e+00	2.56e-01	1.85e+01	1.94e-76	4.10e-75	BRCA

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Sex-biased somatic mutation for WT1

∗For more information on exon skipping events please check the ExonskipDB database.

Gene ID

Cancer Type

Hugo Symbol

Male

Female

pval

ci.up

ci.low

adjPval

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DNA methylation with beta values for WT1

Landscape of DNA methylation across multiple cancer types.

Differentially expressed CpG sites between male tumor and female tumor patients.

Cancer Type	CpG Site	Position	CpG Island	Position to Gene	ave1	ave2	wilcoxon.w	wilcoxon.p	padj	dBeta
BRCA	cg14657517	chr11:32435364	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	1.98e-01	4.17e-01	-2.59e+00	9.71e-03	2.64e-02	-2.19e-01
BRCA	cg21548155	chr11:32434794	CGI:chr11:32433328-32435765	promoter,exon,CDS,gene body	2.94e-01	5.60e-01	-3.04e+00	2.33e-03	1.47e-02	-2.66e-01
BRCA	cg19074340	chr11:32435366	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	2.33e-01	4.70e-01	-2.75e+00	6.01e-03	2.19e-02	-2.37e-01
BRCA	cg07193766	chr11:32435581	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	1.56e-01	3.40e-01	-2.46e+00	1.38e-02	3.03e-02	-1.83e-01
BRCA	cg19570244	chr11:32435612	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	2.50e-01	5.12e-01	-2.99e+00	2.76e-03	1.59e-02	-2.62e-01
BRCA	cg19126300	chr11:32435616	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	3.20e-01	5.92e-01	-3.03e+00	2.45e-03	1.50e-02	-2.73e-01
BRCA	cg13450005	chr11:32435711	CGI:chr11:32433328-32435765	promoter	1.70e-01	3.76e-01	-2.31e+00	2.08e-02	3.55e-02	-2.06e-01
BRCA	cg26232818	chr11:32435840	CGI:chr11:32433328-32435765	promoter	2.02e-01	3.89e-01	-2.34e+00	1.95e-02	3.46e-02	-1.87e-01
BRCA	cg16092786	chr11:32434189	CGI:chr11:32433328-32435765	promoter,gene body	3.96e-01	5.67e-01	-2.31e+00	2.11e-02	3.57e-02	-1.70e-01
BRCA	cg25563456	chr11:32434523	CGI:chr11:32433328-32435765	promoter,gene body	3.20e-01	5.42e-01	-3.18e+00	1.45e-03	1.16e-02	-2.22e-01
BRCA	cg15107670	chr11:32435213	CGI:chr11:32433328-32435765	promoter,exon,CDS,gene body	2.58e-01	4.66e-01	-2.86e+00	4.28e-03	1.91e-02	-2.07e-01
BRCA	cg13663793	chr11:32435578	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	1.70e-01	3.56e-01	-2.90e+00	3.74e-03	1.81e-02	-1.86e-01
PAAD	cg01952234	chr11:32435584	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	1.83e-01	3.09e-01	-3.85e+00	1.16e-04	6.44e-04	-1.26e-01
PAAD	cg19074340	chr11:32435366	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	2.85e-01	4.01e-01	-3.41e+00	6.58e-04	3.21e-03	-1.17e-01
PAAD	cg07193766	chr11:32435581	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	2.26e-01	3.58e-01	-3.85e+00	1.20e-04	6.66e-04	-1.32e-01
PAAD	cg22975913	chr11:32436181	CGI:chr11:32433328-32435765	promoter	2.45e-01	3.73e-01	-3.91e+00	9.24e-05	5.18e-04	-1.28e-01
PAAD	cg12600018	chr11:32436332	CGI:chr11:32433328-32435765	promoter	2.12e-01	3.12e-01	-4.37e+00	1.22e-05	7.37e-05	-1.00e-01
GBM	cg16294566	chr11:32437110	CGI:chr11:32437876-32438332	promoter	3.24e-01	4.67e-01	-2.29e+00	2.19e-02	3.69e-02	-1.43e-01

Differentially expressed CpG sites between male tumor and male normal patients.

Cancer Type	CpG Site	Position	CpG Island	Position to Gene	ave1	ave2	wilcoxon.w	wilcoxon.p	padj	dBeta
KIRC	cg09257824	chr11:32434096	CGI:chr11:32433328-32435765	promoter,gene body	2.41e-01	1.26e-01	3.73e+00	1.89e-04	3.57e-04	1.15e-01
KIRC	cg16092786	chr11:32434189	CGI:chr11:32433328-32435765	promoter,gene body	2.61e-01	1.37e-01	4.77e+00	1.84e-06	6.17e-06	1.24e-01
LUSC	cg21548155	chr11:32434794	CGI:chr11:32433328-32435765	promoter,exon,CDS,gene body	2.51e-01	1.16e-01	2.38e+00	1.72e-02	2.11e-02	1.36e-01
LUSC	cg19074340	chr11:32435366	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	1.47e-01	1.88e-02	3.24e+00	1.19e-03	2.92e-03	1.28e-01
LUSC	cg19570244	chr11:32435612	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	1.38e-01	2.00e-02	2.51e+00	1.22e-02	1.62e-02	1.18e-01
LUSC	cg19126300	chr11:32435616	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	1.62e-01	2.96e-02	2.11e+00	3.48e-02	3.72e-02	1.32e-01
LUSC	cg22511262	chr11:32433646	CGI:chr11:32433328-32435765	promoter,gene body	3.58e-01	1.28e-01	3.49e+00	4.74e-04	1.60e-03	2.29e-01
LUSC	cg18950778	chr11:32433816	CGI:chr11:32433328-32435765	promoter,gene body	4.41e-01	2.09e-01	4.00e+00	6.36e-05	5.92e-04	2.33e-01
LUSC	cg25586361	chr11:32433898	CGI:chr11:32433328-32435765	promoter,gene body	5.15e-01	2.21e-01	4.14e+00	3.54e-05	5.30e-04	2.94e-01
LUSC	cg09257824	chr11:32434096	CGI:chr11:32433328-32435765	promoter,gene body	4.38e-01	1.51e-01	3.98e+00	6.89e-05	6.07e-04	2.87e-01
LUSC	cg16092786	chr11:32434189	CGI:chr11:32433328-32435765	promoter,gene body	3.52e-01	1.38e-01	3.60e+00	3.20e-04	1.26e-03	2.14e-01
LUSC	cg25563456	chr11:32434523	CGI:chr11:32433328-32435765	promoter,gene body	2.41e-01	1.12e-01	3.17e+00	1.50e-03	3.42e-03	1.29e-01
LUSC	cg15107670	chr11:32435213	CGI:chr11:32433328-32435765	promoter,exon,CDS,gene body	2.45e-01	1.32e-01	2.32e+00	2.05e-02	2.43e-02	1.13e-01
LUSC	cg12600018	chr11:32436332	CGI:chr11:32433328-32435765	promoter	2.56e-01	1.07e-01	2.76e+00	5.78e-03	9.10e-03	1.49e-01
LUSC	cg16294566	chr11:32437110	CGI:chr11:32437876-32438332	promoter	4.76e-01	9.36e-02	4.30e+00	1.70e-05	5.26e-04	3.82e-01
BLCA	cg14657517	chr11:32435364	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	2.37e-01	3.96e-02	2.33e+00	2.00e-02	2.45e-02	1.97e-01
BLCA	cg19570244	chr11:32435612	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	2.48e-01	2.22e-02	2.25e+00	2.43e-02	2.85e-02	2.25e-01
BLCA	cg19126300	chr11:32435616	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	2.88e-01	3.35e-02	2.12e+00	3.39e-02	3.70e-02	2.55e-01
BLCA	cg26232818	chr11:32435840	CGI:chr11:32433328-32435765	promoter	2.19e-01	2.67e-02	2.36e+00	1.83e-02	2.28e-02	1.92e-01
BLCA	cg22511262	chr11:32433646	CGI:chr11:32433328-32435765	promoter,gene body	3.20e-01	1.67e-01	2.29e+00	2.19e-02	2.62e-02	1.54e-01
BLCA	cg22975913	chr11:32436181	CGI:chr11:32433328-32435765	promoter	4.19e-01	1.32e-01	2.18e+00	2.89e-02	3.26e-02	2.87e-01
BLCA	cg12600018	chr11:32436332	CGI:chr11:32433328-32435765	promoter	2.79e-01	1.24e-01	1.99e+00	4.65e-02	4.72e-02	1.55e-01
ESCA	cg25586361	chr11:32433898	CGI:chr11:32433328-32435765	promoter,gene body	5.57e-01	4.01e-01	2.41e+00	1.59e-02	3.86e-02	1.55e-01
CHOL	cg21548155	chr11:32434794	CGI:chr11:32433328-32435765	promoter,exon,CDS,gene body	4.16e-01	6.38e-02	2.88e+00	4.04e-03	1.47e-02	3.52e-01
CHOL	cg19074340	chr11:32435366	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	3.73e-01	2.21e-02	2.43e+00	1.50e-02	2.65e-02	3.51e-01
CHOL	cg07193766	chr11:32435581	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	2.40e-01	2.64e-02	2.21e+00	2.70e-02	3.50e-02	2.14e-01
CHOL	cg13450005	chr11:32435711	CGI:chr11:32433328-32435765	promoter	2.29e-01	2.15e-02	2.95e+00	3.19e-03	1.32e-02	2.07e-01
CHOL	cg18950778	chr11:32433816	CGI:chr11:32433328-32435765	promoter,gene body	4.30e-01	2.16e-01	2.65e+00	7.96e-03	1.92e-02	2.14e-01
CHOL	cg09257824	chr11:32434096	CGI:chr11:32433328-32435765	promoter,gene body	3.54e-01	1.47e-01	2.06e+00	3.90e-02	4.26e-02	2.07e-01
CHOL	cg16092786	chr11:32434189	CGI:chr11:32433328-32435765	promoter,gene body	4.12e-01	1.59e-01	2.21e+00	2.70e-02	3.50e-02	2.53e-01
CHOL	cg25563456	chr11:32434523	CGI:chr11:32433328-32435765	promoter,gene body	3.51e-01	1.27e-01	2.51e+00	1.22e-02	2.39e-02	2.24e-01
CHOL	cg22975913	chr11:32436181	CGI:chr11:32433328-32435765	promoter	3.55e-01	9.09e-02	2.51e+00	1.22e-02	2.39e-02	2.64e-01

Differentially expressed CpG sites between female tumor and female normal patients.

Cancer Type	CpG Site	Position	CpG Island	Position to Gene	ave1	ave2	wilcoxon.w	wilcoxon.p	padj	dBeta
BRCA	cg14657517	chr11:32435364	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	1.98e-01	3.97e-02	7.34e+00	2.13e-13	6.88e-13	1.58e-01
BRCA	cg21548155	chr11:32434794	CGI:chr11:32433328-32435765	promoter,exon,CDS,gene body	2.94e-01	9.52e-02	8.63e+00	5.88e-18	2.69e-17	1.98e-01
BRCA	cg19074340	chr11:32435366	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	2.33e-01	3.13e-02	6.79e+00	1.15e-11	3.24e-11	2.02e-01
BRCA	cg07193766	chr11:32435581	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	1.56e-01	2.90e-02	5.93e+00	3.12e-09	7.27e-09	1.27e-01
BRCA	cg19570244	chr11:32435612	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	2.50e-01	4.21e-02	8.46e+00	2.72e-17	1.18e-16	2.08e-01
BRCA	cg19126300	chr11:32435616	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	3.20e-01	6.33e-02	8.64e+00	5.60e-18	2.57e-17	2.56e-01
BRCA	cg13450005	chr11:32435711	CGI:chr11:32433328-32435765	promoter	1.70e-01	2.67e-02	9.35e+00	8.75e-21	5.06e-20	1.43e-01
BRCA	cg26232818	chr11:32435840	CGI:chr11:32433328-32435765	promoter	2.02e-01	2.99e-02	8.48e+00	2.24e-17	9.81e-17	1.72e-01
BRCA	cg22511262	chr11:32433646	CGI:chr11:32433328-32435765	promoter,gene body	3.49e-01	1.48e-01	9.59e+00	8.50e-22	5.37e-21	2.01e-01
BRCA	cg18950778	chr11:32433816	CGI:chr11:32433328-32435765	promoter,gene body	4.48e-01	2.19e-01	1.26e+01	1.22e-36	4.77e-35	2.30e-01
BRCA	cg25586361	chr11:32433898	CGI:chr11:32433328-32435765	promoter,gene body	4.75e-01	2.97e-01	8.93e+00	4.43e-19	2.22e-18	1.78e-01
BRCA	cg09257824	chr11:32434096	CGI:chr11:32433328-32435765	promoter,gene body	3.74e-01	1.51e-01	1.05e+01	9.90e-26	9.02e-25	2.23e-01
BRCA	cg16092786	chr11:32434189	CGI:chr11:32433328-32435765	promoter,gene body	3.96e-01	1.30e-01	1.23e+01	1.39e-34	3.82e-33	2.66e-01
BRCA	cg25563456	chr11:32434523	CGI:chr11:32433328-32435765	promoter,gene body	3.20e-01	1.30e-01	9.30e+00	1.38e-20	7.86e-20	1.90e-01
BRCA	cg15107670	chr11:32435213	CGI:chr11:32433328-32435765	promoter,exon,CDS,gene body	2.58e-01	1.29e-01	5.50e+00	3.82e-08	8.10e-08	1.30e-01
BRCA	cg13663793	chr11:32435578	CGI:chr11:32433328-32435765	UTR,promoter,exon,gene body	1.70e-01	6.48e-02	7.57e+00	3.87e-14	1.32e-13	1.05e-01
BRCA	cg16294566	chr11:32437110	CGI:chr11:32437876-32438332	promoter	4.20e-01	1.38e-01	3.15e+00	1.65e-03	2.09e-03	2.82e-01
LUAD	cg22511262	chr11:32433646	CGI:chr11:32433328-32435765	promoter,gene body	2.24e-01	1.22e-01	3.21e+00	1.32e-03	3.84e-03	1.02e-01
LIHC	cg21548155	chr11:32434794	CGI:chr11:32433328-32435765	promoter,exon,CDS,gene body	2.36e-01	1.03e-01	2.11e+00	3.50e-02	3.77e-02	1.33e-01
KIRP	cg22511262	chr11:32433646	CGI:chr11:32433328-32435765	promoter,gene body	3.97e-01	1.55e-01	1.98e+00	4.78e-02	4.84e-02	2.42e-01

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Exon skipping events with PSI in TCGA for WT1

∗Please access ExonSkipDB for exon skipping annotation.

Landscape of exon skipping events across multiple cancer types.

Differentially expressed exon skipping events between male tumor and female tumor patients.

Cancer Type

Exon Skipping

ave.female_T

ave.female_N

wilcoxon.w

wilcoxon.p

padj

dPSI

Differentially expressed exon skipping events between male tumor and male normal patients.

Cancer Type

Exon Skipping

ave.female_T

ave.female_N

wilcoxon.w

wilcoxon.p

padj

dPSI

Differentially expressed exon skipping events between female tumor and female normal patients.

Cancer Type

Exon Skipping

ave.female_T

ave.female_N

wilcoxon.w

wilcoxon.p

padj

dPSI

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RNA A-to-I editing events in TCGA for WT1

∗Please access CAeditome for RNA editing annotation.

Differentially expressed RNA editing events between male tumor and female tumor patients.

Cancer Type

Transcript

Editing

ave.male_T

ave.female_T

wilcoxon.w

wilcoxon.p

p_adj

dFre

Differentially expressed RNA editing events between male tumor and male normal patients.

Cancer Type

Transcript

Editing

ave.male_T

ave.female_T

wilcoxon.w

wilcoxon.p

p_adj

dFre

Differentially expressed RNA editing events between female tumor and female normal patients.

Cancer Type

Transcript

Editing

ave.male_T

ave.female_T

wilcoxon.w

wilcoxon.p

p_adj

dFre

Protein coding RNA editing(s).

Editing Position

Variant Type

Gene Symbol

Transcript ID

NTchange

AAchange

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Sex-biased TF-Gene network for WT1

TFs related to WT1.
∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98.
∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98.

Cancer Type	TF	Target Gene	Male Edge Score	Male Edge Threshold	Female Edge Score	Female Edge Threshold	Type
MESO	FOXA1	WT1	2.33e+00	2.90e-03	3.96e+00	9.81e-01	Female-biased
MESO	FOXA3	WT1	2.44e+00	3.00e-03	4.06e+00	9.83e-01	Female-biased
MESO	FOXR2	WT1	2.08e+00	1.26e-03	3.93e+00	9.83e-01	Female-biased
MESO	POU3F3	WT1	2.42e+00	3.67e-03	3.98e+00	9.81e-01	Female-biased
MESO	ZNF25	WT1	2.18e+00	1.68e-03	3.95e+00	9.83e-01	Female-biased
MESO	ZNF79	WT1	2.05e+00	5.77e-04	4.10e+00	9.87e-01	Female-biased

WT1 related gene.
∗Only the gene encode TF might with this result.
∗For more information please check Sex-biased TF-Coding gene network.

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Sex-biased RBP-ES network for WT1

RBPs related to ES in WT1.
∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98.
∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98.

Cancer Type

RBP

Target ES

Male Edge Score

Male Edge Threshold

Female Edge Score

Female Edge Threshold

Type

WT1 related ES.
∗Only the gene encode RBP might with this result.
∗For more information please check Sex-biased RBP-ES network in cancer.

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Sex-biased CeRNA regulation of gene

Sex-biased CeRNA regulation of gene.

Gene ID

ceRNA(lncRNA-miRNA-mRNA)

Group

Cancer Type

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Sex-biased eQTL regulation of gene

Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).

eQTL

Description

Male-specific eQTL regulation.

SNP ID

SNP Info

Position to Gene

Effect Score

FDR

Cancer Type

Biased Type

Female-specific eQTL regulation.

SNP ID	SNP Info	Position to Gene	Effect Score	FDR	Cancer Type	Biased Type
rs71466595	chr11:32488555:A:G	-	0.136602539154551	0.0114308455937219	SARC	Male-baised eQTL
rs12803539	chr11:32489246:G:A	-	0.136602539154551	0.0114308455937219	SARC	Male-baised eQTL
rs12274822	chr11:32489465:G:T	-	0.136602539154551	0.0114308455937219	SARC	Male-baised eQTL
rs7118228	chr11:32490882:A:T	-	0.136602539154551	0.0114308455937219	SARC	Male-baised eQTL
rs9735433	chr11:32492498:G:A	-	0.136602539154551	0.0114308455937219	SARC	Male-baised eQTL

Opposite sex-biased eQTL regulation.

SNP ID

SNP Info

Position to Gene

Male Effect

Male FDR

Female Effect

Female FDR

Sex-biased Gene in Cancer

Cancer Type

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Sex-biased eQTM regulation of gene

Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table).

eQTM	Description
	Gene ID: ENSG00000184937
	CpG Site: cg15446391
	Position to Gene: gene
	Male Effect: -
	Female Effect: -0.363887400691609

Male-specific eQTM regulation.

CpG Site

CpG Postion

Position to Gene

Effect Score

FDR

Cor.r

Cor.Pvalue

Cancer Type

Female-specific eQTM regulation.

CpG Site	CpG Postion	Position to Gene	Effect Score	FDR	Cor.r	Cor.Pvalue	Cancer Type
cg15446391	chr11:32430824	gene	-0.363887400691609	1.84998441345069e-05	-0.47334868898836036	2.0787407859530013e-09	SARC

Opposite sex-biased eQTM regulation.

CpG Site

CpG Postion

CpG Island

Position to Gene

Male Effect

Male FDR

Female Effect

Female FDR

Male Cor

Male P-value

Female Cor

Female P-value

Sex-biased Coding Gene

Cancer Type

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Sex-biased sQTL regulation of gene

Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).

sQTL

Description

Male-specific sQTL regulation.

ES ID

Skipped Exon

ORF Anno

SNP ID

SNP Info

SNP Position to ES

Effect Score

FDR

Cancer Type

Biased Type

Female-specific sQTL regulation.

ES ID

Skipped Exon

ORF Anno

SNP ID

SNP Info

SNP Position to ES

Effect Score

FDR

Cancer Type

Biased Type

Opposite sex-biased sQTL regulation.

ES ID

Skipped Exon

ORF Anno

SNP ID

SNP Info

SNP Position to ES

Male Effect

Male FDR

Female Effect

Female FDR

Cancer Type

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Sex-biased sQTM regulation of gene

Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).

sQTM

Description

Male-specific sQTM regulation.

EX ID

Skipped Exon

CPG Site

CPG Position

Position to EX Events

Effect Score

FDR

Cor.r

Cor.Pvalue

ORF_anno

Cancer Type

Female-specific sQTM regulation.

EX ID

Skipped Exon

CPG Site

CPG Position

Position to EX Events

Effect Score

FDR

Cor.r

Cor.Pvalue

ORF_anno

Cancer Type

Opposite sex-biased sQTM regulation.

EX ID

EX Info

Skipped Exon

CPG Site

CPG Position

CPG Island

Position to EX Events

Male Effect

Male FDR

Female Effect

Female FDR

Male Correlation

Male P-value

Female Correlation

Female P-value

ORF_anno

Cancer Type

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Related disease information of WT1

Diseases associated with this gene (DisGeNET).

Gene ID	Gene Symbol	Disease ID	Disease Name	Number of PMID	Source
ENSG00000184937	WT1	C0003076	Aniridia	1	CTD_human
ENSG00000184937	WT1	C0006142	Malignant neoplasm of breast	1	CTD_human
ENSG00000184937	WT1	C0007102	Malignant tumor of colon	1	CTD_human
ENSG00000184937	WT1	C0009375	Colonic Neoplasms	1	CTD_human
ENSG00000184937	WT1	C0017636	Glioblastoma	1	CTD_human
ENSG00000184937	WT1	C0017658	Glomerulonephritis	1	CTD_human
ENSG00000184937	WT1	C0019284	Diaphragmatic Hernia	1	CTD_human
ENSG00000184937	WT1	C0023418	leukemia	1	CTD_human
ENSG00000184937	WT1	C0023467	Leukemia, Myelocytic, Acute	2	CTD_human
ENSG00000184937	WT1	C0023473	Myeloid Leukemia, Chronic	1	CTD_human
ENSG00000184937	WT1	C0023487	Acute Promyelocytic Leukemia	1	CTD_human
ENSG00000184937	WT1	C0024121	Lung Neoplasms	1	CTD_human
ENSG00000184937	WT1	C0026998	Acute Myeloid Leukemia, M1	2	CTD_human
ENSG00000184937	WT1	C0027708	Nephroblastoma	2	CTD_human
ENSG00000184937	WT1	C0027809	Neurilemmoma	1	CTD_human
ENSG00000184937	WT1	C0029463	Osteosarcoma	1	CTD_human
ENSG00000184937	WT1	C0030297	Pancreatic Neoplasm	1	CTD_human
ENSG00000184937	WT1	C0031149	Peritoneal Neoplasms	1	CTD_human
ENSG00000184937	WT1	C0085215	Ovarian Failure, Premature	1	CTD_human
ENSG00000184937	WT1	C0086367	Gonadotropin-Resistant Ovary Syndrome	1	CTD_human
ENSG00000184937	WT1	C0206115	WAGR Syndrome	1	CTD_human
ENSG00000184937	WT1	C0235833	Congenital diaphragmatic hernia	1	CTD_human
ENSG00000184937	WT1	C0242379	Malignant neoplasm of lung	1	CTD_human
ENSG00000184937	WT1	C0265699	Congenital hernia of foramen of Morgagni	1	CTD_human
ENSG00000184937	WT1	C0265700	Congenital hernia of foramen of Bochdalek	1	CTD_human
ENSG00000184937	WT1	C0334588	Giant Cell Glioblastoma	1	CTD_human
ENSG00000184937	WT1	C0345967	Malignant mesothelioma	1	CTD_human
ENSG00000184937	WT1	C0346647	Malignant neoplasm of pancreas	1	CTD_human
ENSG00000184937	WT1	C0346990	Carcinomatosis of peritoneal cavity	1	CTD_human
ENSG00000184937	WT1	C0678222	Breast Carcinoma	1	CTD_human
ENSG00000184937	WT1	C0751374	Schwannomatosis, Plexiform	1	CTD_human
ENSG00000184937	WT1	C0950121	Denys-Drash Syndrome	1	CTD_human
ENSG00000184937	WT1	C0950122	Frasier Syndrome	1	CTD_human
ENSG00000184937	WT1	C1257931	Mammary Neoplasms, Human	1	CTD_human
ENSG00000184937	WT1	C1458155	Mammary Neoplasms	1	CTD_human
ENSG00000184937	WT1	C1621958	Glioblastoma Multiforme	1	CTD_human
ENSG00000184937	WT1	C1704377	Bright Disease	1	CTD_human
ENSG00000184937	WT1	C1837026	MEACHAM SYNDROME (disorder)	1	CTD_human
ENSG00000184937	WT1	C1879321	Acute Myeloid Leukemia (AML-M2)	2	CTD_human
ENSG00000184937	WT1	C2930471	Bilateral Wilms Tumor	2	CTD_human
ENSG00000184937	WT1	C3151568	NEPHROTIC SYNDROME, TYPE 4	1	CTD_human
ENSG00000184937	WT1	C3494522	Hypergonadotropic Ovarian Failure, X-Linked	1	CTD_human
ENSG00000184937	WT1	C4552079	Premature Ovarian Failure 1	1	CTD_human
ENSG00000184937	WT1	C4704874	Mammary Carcinoma, Human	1	CTD_human

	Gene summary
	Gene structure and Gene expression level
	Sex-biased somatic mutation
	DNA methylation with beta values in gene
	Exon skipping events with PSI in TCGA
	RNA A-to-I editing events in TCGA
	Sex-biased TF-Gene network of gene
	Sex-biased RBP-ES network of gene
	Sex-biased CeRNA regulation of gene
	Sex-biased eQTL regulation of gene
	Sex-biased eQTM regulation of gene
	Sex-biased sQTL regulation of gene
	Sex-biased sQTM regulation of gene
	Related disease information of gene