Home

Download

Statistics

Examples

Help

Contact

Gene: ENSG00000182195

Summary for LDOC1

Gene summary

Gene information	Ensembl ID	ENSG00000182195
	Gene symbol	LDOC1
	Gene name	LDOC1 regulator of NFKB signaling
	HGNC	6548
	Entrez ID	23641
	Gene type	protein_coding
	Synonyms	LDOC1\|Mar7\|Mart7\|SIRH7\|RTL7
	UniProtAcc	O95751

Drugs associated with this gene(DrugBank).

Gene ID

Gene Symbol

Drug ID

Drug Name

Drug Type

Cancer therapeutic drugs associated with this gene(NCI).

Gene ID

Gene Name

Drug ID

Drug Name

Drug Type

Cancer

Top

Structure and expression level for LDOC1

AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure.
∗For more information on exon skipping events please check the ExonskipDB database.
∗For more information on exon skipping events please check the CAeditome database.

Landscape of gene expressions across multiple cancer types.

Differentially expressed gene analysis between tumor male and tumor female samples.

Coding Name	Base Mean	log2FoldChange	lfcSE	Stat	P value	P.adjust Value	Cancer Type
LDOC1	3.32e+03	1.43e+00	2.95e-01	4.83e+00	1.37e-06	7.77e-05	BRCA

Differentially expressed gene analysis between tumor male and normal male samples.

Coding Name	Base Mean	log2FoldChange	lfcSE	Stat	P value	P.adjust Value	Cancer Type
LDOC1	8.00e+02	-1.20e+00	3.10e-01	-3.80e+00	1.60e-04	4.20e-04	HNSC
LDOC1	1.06e+02	-1.31e+00	2.57e-01	-5.09e+00	3.54e-07	1.43e-06	COAD
LDOC1	1.35e+03	2.53e+00	4.88e-01	5.19e+00	2.06e-07	1.72e-06	CHOL

Differentially expressed gene analysis between tumor female and normal female samples.

Coding Name	Base Mean	log2FoldChange	lfcSE	Stat	P value	P.adjust Value	Cancer Type
LDOC1	1.30e+02	-1.24e+00	4.06e-01	-3.06e+00	2.21e-03	6.87e-03	READ

Top

Sex-biased somatic mutation for LDOC1

∗For more information on exon skipping events please check the ExonskipDB database.

Gene ID

Cancer Type

Hugo Symbol

Male

Female

pval

ci.up

ci.low

adjPval

Top

DNA methylation with beta values for LDOC1

Landscape of DNA methylation across multiple cancer types.

Differentially expressed CpG sites between male tumor and female tumor patients.

Cancer Type	CpG Site	Position	CpG Island	Position to Gene	ave1	ave2	wilcoxon.w	wilcoxon.p	padj	dBeta
BRCA	cg25870731	chrX:141176844	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	4.38e-01	3.99e-02	5.16e+00	2.43e-07	1.16e-05	3.98e-01
BRCA	cg09112156	chrX:141177074	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	3.85e-01	1.81e-02	5.16e+00	2.43e-07	1.16e-05	3.67e-01
BRCA	cg27076487	chrX:141177179	CGI:chrX:141176765-141177220	promoter	3.40e-01	2.29e-02	5.16e+00	2.43e-07	1.16e-05	3.17e-01
BRCA	cg22970017	chrX:141176316	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	3.39e-01	1.68e-01	3.57e+00	3.56e-04	4.72e-03	1.71e-01
BRCA	cg16697940	chrX:141177136	CGI:chrX:141176765-141177220	promoter	2.86e-01	2.56e-02	5.06e+00	4.27e-07	1.43e-05	2.61e-01
BRCA	cg20104776	chrX:141176991	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	5.28e-01	1.22e-01	5.16e+00	2.43e-07	1.16e-05	4.06e-01
BRCA	cg00917018	chrX:141177364	CGI:chrX:141176765-141177220	promoter	4.29e-01	5.67e-02	2.89e+00	3.88e-03	1.84e-02	3.72e-01
BRCA	cg19208477	chrX:141177419	CGI:chrX:141176765-141177220	promoter	2.04e-01	5.12e-02	5.00e+00	5.66e-07	1.79e-05	1.53e-01
BRCA	cg14562990	chrX:141177441	CGI:chrX:141176765-141177220	promoter	3.90e-01	8.04e-02	5.15e+00	2.64e-07	1.16e-05	3.09e-01
BRCA	cg15490039	chrX:141177534	CGI:chrX:141176765-141177220	promoter	2.03e-01	6.37e-02	4.76e+00	1.94e-06	5.14e-05	1.40e-01
KIRC	cg16697940	chrX:141177136	CGI:chrX:141176765-141177220	promoter	2.45e-01	2.65e-02	1.39e+01	6.75e-44	1.52e-42	2.18e-01
LGG	cg25870731	chrX:141176844	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	4.46e-01	4.96e-02	1.96e+01	1.74e-85	5.54e-84	3.97e-01
LGG	cg09112156	chrX:141177074	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	3.85e-01	1.85e-02	1.98e+01	7.53e-87	3.74e-85	3.67e-01
LGG	cg27076487	chrX:141177179	CGI:chrX:141176765-141177220	promoter	3.67e-01	2.47e-02	1.97e+01	2.74e-86	1.14e-84	3.42e-01
LGG	cg16697940	chrX:141177136	CGI:chrX:141176765-141177220	promoter	2.23e-01	2.56e-02	1.89e+01	1.64e-79	3.42e-78	1.98e-01
LGG	cg20104776	chrX:141176991	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	5.11e-01	1.08e-01	1.92e+01	6.06e-82	1.44e-80	4.04e-01
LGG	cg00917018	chrX:141177364	CGI:chrX:141176765-141177220	promoter	4.44e-01	6.38e-02	1.80e+01	4.58e-72	7.55e-71	3.80e-01
LGG	cg19208477	chrX:141177419	CGI:chrX:141176765-141177220	promoter	1.74e-01	6.27e-02	1.58e+01	1.90e-56	2.28e-55	1.11e-01
LGG	cg14562990	chrX:141177441	CGI:chrX:141176765-141177220	promoter	4.00e-01	2.46e-01	1.03e+01	6.90e-25	5.11e-24	1.54e-01
LGG	cg15490039	chrX:141177534	CGI:chrX:141176765-141177220	promoter	1.80e-01	6.65e-02	1.55e+01	5.20e-54	5.97e-53	1.13e-01
LUSC	cg25870731	chrX:141176844	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	4.57e-01	1.33e-01	1.29e+01	5.52e-38	8.43e-37	3.24e-01
LUSC	cg09112156	chrX:141177074	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	4.02e-01	1.06e-01	1.24e+01	1.44e-35	2.08e-34	2.96e-01
LUSC	cg27076487	chrX:141177179	CGI:chrX:141176765-141177220	promoter	3.44e-01	7.69e-02	1.27e+01	5.81e-37	8.65e-36	2.67e-01
LUSC	cg22970017	chrX:141176316	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	3.44e-01	2.08e-01	1.03e+01	8.14e-25	9.41e-24	1.35e-01
LUSC	cg16697940	chrX:141177136	CGI:chrX:141176765-141177220	promoter	2.79e-01	7.29e-02	1.22e+01	4.54e-34	6.32e-33	2.07e-01
LUSC	cg20104776	chrX:141176991	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	5.20e-01	2.87e-01	1.15e+01	9.89e-31	1.29e-29	2.33e-01
LUSC	cg00917018	chrX:141177364	CGI:chrX:141176765-141177220	promoter	4.13e-01	1.20e-01	1.18e+01	2.53e-32	3.40e-31	2.93e-01
LUSC	cg19208477	chrX:141177419	CGI:chrX:141176765-141177220	promoter	1.97e-01	9.12e-02	1.14e+01	3.10e-30	4.01e-29	1.06e-01
LUSC	cg14562990	chrX:141177441	CGI:chrX:141176765-141177220	promoter	3.91e-01	1.99e-01	1.11e+01	8.11e-29	1.02e-27	1.92e-01
SKCM	cg25870731	chrX:141176844	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	4.31e-01	9.99e-02	1.65e+01	1.99e-61	3.72e-60	3.31e-01
SKCM	cg09112156	chrX:141177074	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	3.29e-01	4.41e-02	1.71e+01	1.19e-65	2.55e-64	2.85e-01
SKCM	cg27076487	chrX:141177179	CGI:chrX:141176765-141177220	promoter	3.30e-01	6.67e-02	1.57e+01	1.04e-55	1.69e-54	2.63e-01
SKCM	cg16697940	chrX:141177136	CGI:chrX:141176765-141177220	promoter	1.98e-01	4.52e-02	1.42e+01	1.05e-45	1.41e-44	1.53e-01
SKCM	cg20104776	chrX:141176991	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	5.27e-01	2.69e-01	1.31e+01	3.04e-39	3.63e-38	2.58e-01
SKCM	cg00917018	chrX:141177364	CGI:chrX:141176765-141177220	promoter	4.08e-01	1.00e-01	1.39e+01	3.57e-44	4.69e-43	3.08e-01
SKCM	cg14562990	chrX:141177441	CGI:chrX:141176765-141177220	promoter	3.17e-01	1.46e-01	1.34e+01	9.08e-41	1.12e-39	1.71e-01
STAD	cg25870731	chrX:141176844	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	5.98e-01	4.82e-01	5.02e+00	5.04e-07	3.06e-06	1.15e-01
STAD	cg09112156	chrX:141177074	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	5.46e-01	4.18e-01	5.82e+00	5.81e-09	3.96e-08	1.29e-01
STAD	cg27076487	chrX:141177179	CGI:chrX:141176765-141177220	promoter	5.30e-01	3.82e-01	6.33e+00	2.49e-10	1.84e-09	1.48e-01
STAD	cg22970017	chrX:141176316	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	3.96e-01	2.65e-01	8.58e+00	9.75e-18	1.03e-16	1.32e-01
STAD	cg00917018	chrX:141177364	CGI:chrX:141176765-141177220	promoter	6.39e-01	4.45e-01	6.06e+00	1.36e-09	9.60e-09	1.93e-01
KIRP	cg16697940	chrX:141177136	CGI:chrX:141176765-141177220	promoter	2.03e-01	2.63e-02	1.16e+01	2.34e-31	6.82e-30	1.77e-01
SARC	cg25870731	chrX:141176844	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	4.07e-01	7.30e-02	1.30e+01	2.31e-38	9.90e-37	3.34e-01
SARC	cg09112156	chrX:141177074	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	3.40e-01	5.43e-02	1.25e+01	5.95e-36	2.14e-34	2.86e-01
SARC	cg27076487	chrX:141177179	CGI:chrX:141176765-141177220	promoter	2.98e-01	4.49e-02	1.29e+01	7.72e-38	3.15e-36	2.54e-01
SARC	cg16697940	chrX:141177136	CGI:chrX:141176765-141177220	promoter	1.97e-01	4.05e-02	1.09e+01	7.57e-28	1.70e-26	1.57e-01
SARC	cg20104776	chrX:141176991	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	5.05e-01	1.95e-01	1.16e+01	4.31e-31	1.18e-29	3.10e-01
SARC	cg00917018	chrX:141177364	CGI:chrX:141176765-141177220	promoter	4.14e-01	1.13e-01	1.01e+01	7.49e-24	1.29e-22	3.01e-01
SARC	cg14562990	chrX:141177441	CGI:chrX:141176765-141177220	promoter	3.70e-01	2.12e-01	7.72e+00	1.18e-14	1.30e-13	1.58e-01
PCPG	cg25870731	chrX:141176844	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	3.44e-01	4.18e-02	1.16e+01	3.96e-31	1.92e-29	3.02e-01
PCPG	cg09112156	chrX:141177074	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	2.86e-01	1.72e-02	1.16e+01	3.83e-31	1.92e-29	2.69e-01
PCPG	cg27076487	chrX:141177179	CGI:chrX:141176765-141177220	promoter	2.70e-01	2.34e-02	1.16e+01	3.96e-31	1.92e-29	2.47e-01
PCPG	cg22970017	chrX:141176316	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	2.73e-01	8.74e-02	1.02e+01	1.34e-24	1.66e-23	1.85e-01
PCPG	cg20104776	chrX:141176991	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	4.26e-01	1.03e-01	1.16e+01	4.82e-31	1.95e-29	3.23e-01
PCPG	cg00917018	chrX:141177364	CGI:chrX:141176765-141177220	promoter	4.60e-01	6.02e-02	1.05e+01	1.32e-25	1.72e-24	3.99e-01
PCPG	cg14562990	chrX:141177441	CGI:chrX:141176765-141177220	promoter	3.28e-01	1.15e-01	1.03e+01	7.27e-25	9.10e-24	2.13e-01
PCPG	cg15490039	chrX:141177534	CGI:chrX:141176765-141177220	promoter	1.71e-01	6.77e-02	8.30e+00	1.07e-16	8.27e-16	1.03e-01
PAAD	cg25870731	chrX:141176844	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	4.79e-01	2.53e-01	7.00e+00	2.55e-12	2.38e-11	2.26e-01
PAAD	cg09112156	chrX:141177074	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	4.33e-01	2.18e-01	7.49e+00	6.64e-14	6.81e-13	2.15e-01
PAAD	cg27076487	chrX:141177179	CGI:chrX:141176765-141177220	promoter	3.94e-01	1.88e-01	7.59e+00	3.10e-14	3.25e-13	2.06e-01
PAAD	cg22970017	chrX:141176316	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	4.21e-01	2.23e-01	9.27e+00	1.87e-20	2.79e-19	1.98e-01
PAAD	cg16697940	chrX:141177136	CGI:chrX:141176765-141177220	promoter	3.43e-01	2.06e-01	4.92e+00	8.72e-07	5.77e-06	1.37e-01
PAAD	cg20104776	chrX:141176991	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	5.19e-01	3.92e-01	4.58e+00	4.73e-06	2.95e-05	1.27e-01
PAAD	cg00917018	chrX:141177364	CGI:chrX:141176765-141177220	promoter	4.83e-01	2.10e-01	7.13e+00	9.88e-13	9.48e-12	2.74e-01
PAAD	cg14562990	chrX:141177441	CGI:chrX:141176765-141177220	promoter	4.35e-01	3.29e-01	4.73e+00	2.23e-06	1.43e-05	1.06e-01
READ	cg27076487	chrX:141177179	CGI:chrX:141176765-141177220	promoter	6.66e-01	5.28e-01	4.33e+00	1.50e-05	7.90e-05	1.39e-01
READ	cg16697940	chrX:141177136	CGI:chrX:141176765-141177220	promoter	7.30e-01	6.19e-01	2.66e+00	7.88e-03	2.13e-02	1.10e-01
READ	cg00917018	chrX:141177364	CGI:chrX:141176765-141177220	promoter	7.83e-01	6.71e-01	3.06e+00	2.24e-03	8.04e-03	1.12e-01
GBM	cg25870731	chrX:141176844	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	4.81e-01	5.35e-02	6.74e+00	1.63e-11	2.71e-10	4.28e-01
GBM	cg09112156	chrX:141177074	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	4.21e-01	1.90e-02	6.74e+00	1.63e-11	2.71e-10	4.02e-01
GBM	cg27076487	chrX:141177179	CGI:chrX:141176765-141177220	promoter	3.78e-01	2.12e-02	6.74e+00	1.63e-11	2.71e-10	3.57e-01
GBM	cg22970017	chrX:141176316	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	3.27e-01	2.14e-01	3.97e+00	7.12e-05	3.64e-04	1.14e-01
GBM	cg16697940	chrX:141177136	CGI:chrX:141176765-141177220	promoter	2.38e-01	2.58e-02	6.26e+00	3.75e-10	4.02e-09	2.13e-01
GBM	cg20104776	chrX:141176991	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	5.32e-01	1.16e-01	6.71e+00	1.97e-11	3.03e-10	4.15e-01
GBM	cg00917018	chrX:141177364	CGI:chrX:141176765-141177220	promoter	4.82e-01	8.07e-02	4.56e+00	5.22e-06	3.22e-05	4.02e-01
GBM	cg19208477	chrX:141177419	CGI:chrX:141176765-141177220	promoter	1.59e-01	4.91e-02	5.38e+00	7.66e-08	5.94e-07	1.10e-01
GBM	cg14562990	chrX:141177441	CGI:chrX:141176765-141177220	promoter	3.60e-01	1.40e-01	4.99e+00	6.16e-07	4.29e-06	2.20e-01
GBM	cg15490039	chrX:141177534	CGI:chrX:141176765-141177220	promoter	1.58e-01	4.73e-02	4.96e+00	7.11e-07	4.91e-06	1.10e-01
ESCA	cg25870731	chrX:141176844	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	5.67e-01	3.98e-01	2.45e+00	1.41e-02	3.23e-02	1.69e-01
ESCA	cg09112156	chrX:141177074	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	5.28e-01	3.49e-01	2.90e+00	3.78e-03	1.36e-02	1.79e-01
ESCA	cg27076487	chrX:141177179	CGI:chrX:141176765-141177220	promoter	4.75e-01	3.18e-01	2.56e+00	1.05e-02	2.74e-02	1.57e-01
ESCA	cg22970017	chrX:141176316	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	3.36e-01	2.19e-01	4.43e+00	9.56e-06	5.91e-05	1.17e-01
ESCA	cg16697940	chrX:141177136	CGI:chrX:141176765-141177220	promoter	5.16e-01	3.69e-01	2.44e+00	1.45e-02	3.27e-02	1.48e-01
ESCA	cg00917018	chrX:141177364	CGI:chrX:141176765-141177220	promoter	6.07e-01	3.92e-01	2.51e+00	1.22e-02	2.98e-02	2.15e-01
ESCA	cg14562990	chrX:141177441	CGI:chrX:141176765-141177220	promoter	5.21e-01	4.03e-01	2.05e+00	4.07e-02	4.75e-02	1.18e-01
LAML	cg25870731	chrX:141176844	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	5.41e-01	2.35e-01	7.01e+00	2.44e-12	1.23e-11	3.06e-01
LAML	cg09112156	chrX:141177074	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	5.22e-01	2.61e-01	5.93e+00	3.04e-09	1.29e-08	2.61e-01
LAML	cg27076487	chrX:141177179	CGI:chrX:141176765-141177220	promoter	5.20e-01	2.62e-01	5.77e+00	8.04e-09	3.34e-08	2.58e-01
LAML	cg22970017	chrX:141176316	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	5.38e-01	4.22e-01	2.88e+00	4.00e-03	1.06e-02	1.15e-01
LAML	cg16697940	chrX:141177136	CGI:chrX:141176765-141177220	promoter	4.64e-01	2.09e-01	6.14e+00	8.21e-10	3.59e-09	2.55e-01
LAML	cg20104776	chrX:141176991	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	6.36e-01	5.05e-01	2.52e+00	1.19e-02	2.44e-02	1.32e-01
LAML	cg00917018	chrX:141177364	CGI:chrX:141176765-141177220	promoter	5.12e-01	1.94e-01	7.57e+00	3.78e-14	2.13e-13	3.18e-01
LAML	cg19208477	chrX:141177419	CGI:chrX:141176765-141177220	promoter	3.06e-01	1.62e-01	5.95e+00	2.71e-09	1.15e-08	1.44e-01
LAML	cg14562990	chrX:141177441	CGI:chrX:141176765-141177220	promoter	4.74e-01	2.64e-01	6.52e+00	6.95e-11	3.23e-10	2.10e-01
LAML	cg15490039	chrX:141177534	CGI:chrX:141176765-141177220	promoter	2.49e-01	1.42e-01	4.47e+00	7.65e-06	2.73e-05	1.07e-01
THYM	cg25870731	chrX:141176844	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	4.25e-01	5.38e-02	9.39e+00	6.07e-21	1.00e-19	3.71e-01
THYM	cg09112156	chrX:141177074	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	3.75e-01	2.37e-02	9.40e+00	5.48e-21	1.00e-19	3.51e-01
THYM	cg27076487	chrX:141177179	CGI:chrX:141176765-141177220	promoter	3.18e-01	2.73e-02	9.38e+00	6.38e-21	1.02e-19	2.90e-01
THYM	cg22970017	chrX:141176316	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	4.39e-01	2.73e-01	7.34e+00	2.21e-13	1.21e-12	1.66e-01
THYM	cg16697940	chrX:141177136	CGI:chrX:141176765-141177220	promoter	2.47e-01	2.41e-02	9.23e+00	2.59e-20	3.18e-19	2.22e-01
THYM	cg20104776	chrX:141176991	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	5.00e-01	2.00e-01	9.39e+00	5.77e-21	1.00e-19	2.99e-01
THYM	cg00917018	chrX:141177364	CGI:chrX:141176765-141177220	promoter	3.99e-01	6.27e-02	8.19e+00	2.69e-16	1.89e-15	3.36e-01
THYM	cg19208477	chrX:141177419	CGI:chrX:141176765-141177220	promoter	1.84e-01	6.09e-02	8.62e+00	6.53e-18	5.42e-17	1.23e-01
THYM	cg14562990	chrX:141177441	CGI:chrX:141176765-141177220	promoter	3.83e-01	1.10e-01	9.34e+00	9.55e-21	1.33e-19	2.74e-01
THYM	cg15490039	chrX:141177534	CGI:chrX:141176765-141177220	promoter	1.85e-01	7.77e-02	7.05e+00	1.74e-12	8.91e-12	1.07e-01
MESO	cg25870731	chrX:141176844	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	3.79e-01	5.28e-02	6.05e+00	1.46e-09	2.54e-08	3.26e-01
MESO	cg09112156	chrX:141177074	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	3.04e-01	3.39e-02	5.96e+00	2.56e-09	3.61e-08	2.70e-01
MESO	cg27076487	chrX:141177179	CGI:chrX:141176765-141177220	promoter	2.76e-01	2.92e-02	6.05e+00	1.46e-09	2.54e-08	2.47e-01
MESO	cg16697940	chrX:141177136	CGI:chrX:141176765-141177220	promoter	1.97e-01	2.71e-02	5.99e+00	2.08e-09	3.08e-08	1.70e-01
MESO	cg20104776	chrX:141176991	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	4.50e-01	1.53e-01	6.01e+00	1.80e-09	2.82e-08	2.96e-01
MESO	cg00917018	chrX:141177364	CGI:chrX:141176765-141177220	promoter	3.61e-01	8.46e-02	5.10e+00	3.32e-07	2.84e-06	2.76e-01
MESO	cg19208477	chrX:141177419	CGI:chrX:141176765-141177220	promoter	1.72e-01	7.12e-02	5.32e+00	1.04e-07	9.51e-07	1.01e-01
MESO	cg14562990	chrX:141177441	CGI:chrX:141176765-141177220	promoter	3.25e-01	1.48e-01	4.63e+00	3.73e-06	2.78e-05	1.77e-01
UVM	cg25870731	chrX:141176844	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	2.89e-01	5.05e-02	7.62e+00	2.57e-14	9.97e-13	2.39e-01
UVM	cg09112156	chrX:141177074	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	2.85e-01	1.54e-02	7.54e+00	4.68e-14	1.11e-12	2.69e-01
UVM	cg27076487	chrX:141177179	CGI:chrX:141176765-141177220	promoter	2.46e-01	2.24e-02	6.96e+00	3.43e-12	3.35e-11	2.23e-01
UVM	cg16697940	chrX:141177136	CGI:chrX:141176765-141177220	promoter	1.33e-01	2.25e-02	4.61e+00	3.99e-06	1.71e-05	1.11e-01
UVM	cg20104776	chrX:141176991	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	3.80e-01	9.45e-02	7.51e+00	5.84e-14	1.23e-12	2.86e-01
UVM	cg00917018	chrX:141177364	CGI:chrX:141176765-141177220	promoter	3.19e-01	5.56e-02	7.12e+00	1.05e-12	1.14e-11	2.64e-01
UVM	cg19208477	chrX:141177419	CGI:chrX:141176765-141177220	promoter	1.53e-01	5.03e-02	4.87e+00	1.10e-06	5.10e-06	1.03e-01
UVM	cg14562990	chrX:141177441	CGI:chrX:141176765-141177220	promoter	2.59e-01	1.10e-01	5.58e+00	2.38e-08	1.39e-07	1.49e-01
UVM	cg15490039	chrX:141177534	CGI:chrX:141176765-141177220	promoter	1.92e-01	6.92e-02	3.17e+00	1.54e-03	4.52e-03	1.23e-01
ACC	cg00917018	chrX:141177364	CGI:chrX:141176765-141177220	promoter	4.09e-01	5.23e-02	7.37e+00	1.71e-13	3.92e-12	3.57e-01
ACC	cg09112156	chrX:141177074	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	3.69e-01	1.72e-02	7.47e+00	8.02e-14	2.68e-12	3.51e-01
ACC	cg14562990	chrX:141177441	CGI:chrX:141176765-141177220	promoter	3.29e-01	1.05e-01	6.33e+00	2.53e-10	2.99e-09	2.24e-01
ACC	cg16697940	chrX:141177136	CGI:chrX:141176765-141177220	promoter	1.98e-01	2.12e-02	6.66e+00	2.80e-11	3.72e-10	1.77e-01
ACC	cg20104776	chrX:141176991	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	4.88e-01	1.25e-01	7.41e+00	1.27e-13	3.15e-12	3.62e-01
ACC	cg22970017	chrX:141176316	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	3.57e-01	1.92e-01	4.61e+00	4.06e-06	3.21e-05	1.65e-01
ACC	cg25870731	chrX:141176844	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	4.18e-01	4.71e-02	7.46e+00	8.66e-14	2.68e-12	3.71e-01
ACC	cg27076487	chrX:141177179	CGI:chrX:141176765-141177220	promoter	3.25e-01	2.87e-02	7.27e+00	3.62e-13	7.24e-12	2.97e-01
KICH	cg25870731	chrX:141176844	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	2.85e-01	6.11e-02	6.40e+00	1.55e-10	3.04e-09	2.24e-01
KICH	cg09112156	chrX:141177074	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	2.18e-01	2.18e-02	6.59e+00	4.45e-11	1.88e-09	1.96e-01
KICH	cg27076487	chrX:141177179	CGI:chrX:141176765-141177220	promoter	1.60e-01	2.80e-02	6.28e+00	3.38e-10	5.62e-09	1.32e-01
KICH	cg22970017	chrX:141176316	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	2.57e-01	1.03e-01	4.97e+00	6.77e-07	6.25e-06	1.54e-01
KICH	cg20104776	chrX:141176991	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	4.01e-01	1.55e-01	5.96e+00	2.54e-09	3.30e-08	2.46e-01
KICH	cg00917018	chrX:141177364	CGI:chrX:141176765-141177220	promoter	2.80e-01	8.22e-02	5.62e+00	1.87e-08	2.06e-07	1.97e-01
DLBC	cg09112156	chrX:141177074	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	5.85e-01	4.74e-01	2.61e+00	9.13e-03	2.13e-02	1.11e-01
DLBC	cg27076487	chrX:141177179	CGI:chrX:141176765-141177220	promoter	5.70e-01	4.17e-01	2.75e+00	5.92e-03	1.54e-02	1.53e-01
DLBC	cg00917018	chrX:141177364	CGI:chrX:141176765-141177220	promoter	6.76e-01	4.98e-01	2.57e+00	1.03e-02	2.32e-02	1.78e-01
CHOL	cg25870731	chrX:141176844	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	4.98e-01	6.61e-02	5.03e+00	4.90e-07	5.60e-06	4.32e-01
CHOL	cg09112156	chrX:141177074	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	4.37e-01	4.63e-02	5.00e+00	5.79e-07	6.26e-06	3.91e-01
CHOL	cg27076487	chrX:141177179	CGI:chrX:141176765-141177220	promoter	4.23e-01	4.32e-02	5.03e+00	4.90e-07	5.60e-06	3.80e-01
CHOL	cg22970017	chrX:141176316	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	4.09e-01	1.46e-01	4.58e+00	4.55e-06	3.43e-05	2.63e-01
CHOL	cg16697940	chrX:141177136	CGI:chrX:141176765-141177220	promoter	4.19e-01	3.74e-02	4.74e+00	2.10e-06	1.72e-05	3.81e-01
CHOL	cg20104776	chrX:141176991	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	5.64e-01	1.70e-01	4.62e+00	3.91e-06	2.98e-05	3.94e-01
CHOL	cg00917018	chrX:141177364	CGI:chrX:141176765-141177220	promoter	4.96e-01	9.61e-02	4.30e+00	1.72e-05	1.08e-04	4.00e-01
CHOL	cg19208477	chrX:141177419	CGI:chrX:141176765-141177220	promoter	2.50e-01	6.98e-02	4.14e+00	3.49e-05	2.01e-04	1.80e-01
CHOL	cg14562990	chrX:141177441	CGI:chrX:141176765-141177220	promoter	4.63e-01	1.11e-01	4.84e+00	1.30e-06	1.17e-05	3.52e-01
CHOL	cg15490039	chrX:141177534	CGI:chrX:141176765-141177220	promoter	2.79e-01	1.08e-01	4.39e+00	1.12e-05	7.39e-05	1.71e-01

Differentially expressed CpG sites between male tumor and male normal patients.

Cancer Type	CpG Site	Position	CpG Island	Position to Gene	ave1	ave2	wilcoxon.w	wilcoxon.p	padj	dBeta
LUAD	cg20104776	chrX:141176991	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	2.76e-01	1.62e-01	3.92e+00	8.81e-05	2.53e-04	1.13e-01
HNSC	cg25870731	chrX:141176844	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	3.17e-01	6.23e-02	4.60e+00	4.14e-06	1.84e-05	2.55e-01
HNSC	cg09112156	chrX:141177074	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	2.74e-01	3.81e-02	4.42e+00	9.73e-06	3.72e-05	2.35e-01
HNSC	cg27076487	chrX:141177179	CGI:chrX:141176765-141177220	promoter	2.14e-01	2.36e-02	4.89e+00	9.87e-07	5.75e-06	1.90e-01
HNSC	cg20104776	chrX:141176991	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	4.38e-01	1.75e-01	4.59e+00	4.34e-06	1.91e-05	2.63e-01
HNSC	cg19208477	chrX:141177419	CGI:chrX:141176765-141177220	promoter	2.00e-01	7.21e-02	3.48e+00	4.95e-04	9.99e-04	1.28e-01
LUSC	cg20104776	chrX:141176991	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	2.87e-01	1.55e-01	3.03e+00	2.46e-03	4.84e-03	1.32e-01
COAD	cg14562990	chrX:141177441	CGI:chrX:141176765-141177220	promoter	6.41e-01	3.41e-01	5.29e+00	1.19e-07	5.16e-06	3.01e-01
LIHC	cg25870731	chrX:141176844	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	2.54e-01	7.87e-02	2.27e+00	2.30e-02	2.53e-02	1.76e-01
LIHC	cg27076487	chrX:141177179	CGI:chrX:141176765-141177220	promoter	2.07e-01	3.16e-02	3.80e+00	1.43e-04	2.84e-04	1.75e-01
LIHC	cg16697940	chrX:141177136	CGI:chrX:141176765-141177220	promoter	1.58e-01	2.77e-02	2.63e+00	8.43e-03	1.05e-02	1.30e-01
LIHC	cg20104776	chrX:141176991	CGI:chrX:141176765-141177220	promoter,exon,CDS,gene body	5.01e-01	2.65e-01	3.81e+00	1.37e-04	2.73e-04	2.36e-01
LIHC	cg00917018	chrX:141177364	CGI:chrX:141176765-141177220	promoter	2.88e-01	9.26e-02	2.68e+00	7.41e-03	9.34e-03	1.95e-01

Differentially expressed CpG sites between female tumor and female normal patients.

Cancer Type	CpG Site	Position	CpG Island	Position to Gene	ave1	ave2	wilcoxon.w	wilcoxon.p	padj	dBeta
BRCA	cg22970017	chrX:141176316	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	3.39e-01	4.44e-01	-9.56e+00	1.20e-21	7.46e-21	-1.05e-01
BRCA	cg16697940	chrX:141177136	CGI:chrX:141176765-141177220	promoter	2.86e-01	1.80e-01	5.82e+00	5.98e-09	1.36e-08	1.06e-01
BRCA	cg00917018	chrX:141177364	CGI:chrX:141176765-141177220	promoter	4.29e-01	5.33e-01	-7.89e+00	3.00e-15	1.11e-14	-1.04e-01
KIRC	cg16697940	chrX:141177136	CGI:chrX:141176765-141177220	promoter	2.45e-01	9.82e-02	2.56e+00	1.05e-02	1.76e-02	1.46e-01
LUAD	cg16697940	chrX:141177136	CGI:chrX:141176765-141177220	promoter	3.19e-01	1.84e-01	2.61e+00	9.16e-03	1.48e-02	1.35e-01
BLCA	cg22970017	chrX:141176316	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	3.22e-01	4.45e-01	-3.34e+00	8.47e-04	4.48e-03	-1.23e-01
LIHC	cg22970017	chrX:141176316	CGI:chrX:141176765-141177220	UTR,promoter,exon,gene body	3.23e-01	4.38e-01	-3.42e+00	6.29e-04	1.57e-03	-1.15e-01
KIRP	cg00917018	chrX:141177364	CGI:chrX:141176765-141177220	promoter	3.87e-01	5.41e-01	-3.18e+00	1.46e-03	4.90e-03	-1.54e-01

Top

Exon skipping events with PSI in TCGA for LDOC1

∗Please access ExonSkipDB for exon skipping annotation.

Differentially expressed exon skipping events between male tumor and female tumor patients.

Cancer Type

Exon Skipping

ave.female_T

ave.female_N

wilcoxon.w

wilcoxon.p

padj

dPSI

Differentially expressed exon skipping events between male tumor and male normal patients.

Cancer Type

Exon Skipping

ave.female_T

ave.female_N

wilcoxon.w

wilcoxon.p

padj

dPSI

Differentially expressed exon skipping events between female tumor and female normal patients.

Cancer Type

Exon Skipping

ave.female_T

ave.female_N

wilcoxon.w

wilcoxon.p

padj

dPSI

Top

RNA A-to-I editing events in TCGA for LDOC1

∗Please access CAeditome for RNA editing annotation.

Differentially expressed RNA editing events between male tumor and female tumor patients.

Cancer Type

Transcript

Editing

ave.male_T

ave.female_T

wilcoxon.w

wilcoxon.p

p_adj

dFre

Differentially expressed RNA editing events between male tumor and male normal patients.

Cancer Type

Transcript

Editing

ave.male_T

ave.female_T

wilcoxon.w

wilcoxon.p

p_adj

dFre

Differentially expressed RNA editing events between female tumor and female normal patients.

Cancer Type

Transcript

Editing

ave.male_T

ave.female_T

wilcoxon.w

wilcoxon.p

p_adj

dFre

Protein coding RNA editing(s).

Editing Position

Variant Type

Gene Symbol

Transcript ID

NTchange

AAchange

Top

Sex-biased TF-Gene network for LDOC1

TFs related to LDOC1.
∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98.
∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98.

Cancer Type	TF	Target Gene	Male Edge Score	Male Edge Threshold	Female Edge Score	Female Edge Threshold	Type
PCPG	BARX1	LDOC1	3.11e+00	3.31e-03	4.16e+00	9.86e-01	Female-biased
PCPG	HMX2	LDOC1	3.72e+00	8.10e-03	4.57e+00	9.86e-01	Female-biased
PCPG	POU2F2	LDOC1	2.65e+00	1.62e-03	3.84e+00	9.80e-01	Female-biased
PCPG	POU2F3	LDOC1	3.37e+00	7.54e-03	4.23e+00	9.83e-01	Female-biased
PCPG	ZNF211	LDOC1	4.72e+00	1.60e-02	5.42e+00	9.82e-01	Female-biased
PCPG	ZNF35	LDOC1	2.51e+00	6.86e-04	3.88e+00	9.83e-01	Female-biased
PCPG	ZNF584	LDOC1	2.60e+00	1.05e-03	3.88e+00	9.82e-01	Female-biased
PCPG	ZNF620	LDOC1	2.84e+00	2.46e-03	3.95e+00	9.83e-01	Female-biased
PCPG	ZNF79	LDOC1	1.96e+00	7.73e-05	3.78e+00	9.80e-01	Female-biased

LDOC1 related gene.
∗Only the gene encode TF might with this result.
∗For more information please check Sex-biased TF-Coding gene network.

Top

Sex-biased RBP-ES network for LDOC1

RBPs related to ES in LDOC1.
∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98.
∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98.

Cancer Type

RBP

Target ES

Male Edge Score

Male Edge Threshold

Female Edge Score

Female Edge Threshold

Type

LDOC1 related ES.
∗Only the gene encode RBP might with this result.
∗For more information please check Sex-biased RBP-ES network in cancer.

Top

Sex-biased CeRNA regulation of gene

Sex-biased CeRNA regulation of gene.

Gene ID

ceRNA(lncRNA-miRNA-mRNA)

Group

Cancer Type

Top

Sex-biased eQTL regulation of gene

Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).

eQTL

Description

Male-specific eQTL regulation.

SNP ID

SNP Info

Position to Gene

Effect Score

FDR

Cancer Type

Biased Type

Female-specific eQTL regulation.

SNP ID

SNP Info

Position to Gene

Effect Score

FDR

Cancer Type

Biased Type

Opposite sex-biased eQTL regulation.

SNP ID

SNP Info

Position to Gene

Male Effect

Male FDR

Female Effect

Female FDR

Sex-biased Gene in Cancer

Cancer Type

Top

Sex-biased eQTM regulation of gene

Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table).

eQTM	Description
	Gene ID: ENSG00000182195
	CpG Site: cg20104776
	Position to Gene: gene,exon,CDS,promoter
	Male Effect: -0.105215774288751
	Female Effect: -
	Gene ID: ENSG00000182195
	CpG Site: cg00917018
	Position to Gene: promoter
	Male Effect: -0.0657545567320079
	Female Effect: -
	Gene ID: ENSG00000182195
	CpG Site: cg09112156
	Position to Gene: gene,exon,promoter,UTR
	Male Effect: -0.0746618227748657
	Female Effect: -
	Gene ID: ENSG00000182195
	CpG Site: cg14562990
	Position to Gene: promoter
	Male Effect: -0.0770802072128468
	Female Effect: -
	Gene ID: ENSG00000182195
	CpG Site: cg25870731
	Position to Gene: gene,exon,CDS,promoter
	Male Effect: -0.070482713374659
	Female Effect: -
	Gene ID: ENSG00000182195
	CpG Site: cg20104776
	Position to Gene: gene,exon,CDS,promoter
	Male Effect: -0.0577558958050777
	Female Effect: -
	Gene ID: ENSG00000182195
	CpG Site: cg20104776
	Position to Gene: gene,exon,CDS,promoter
	Male Effect: -0.0897561147737711
	Female Effect: -
	Gene ID: ENSG00000182195
	CpG Site: cg00917018
	Position to Gene: promoter
	Male Effect: -0.107097293867189
	Female Effect: -
	Gene ID: ENSG00000182195
	CpG Site: cg27076487
	Position to Gene: promoter
	Male Effect: -0.109769052264981
	Female Effect: -
	Gene ID: ENSG00000182195
	CpG Site: cg20104776
	Position to Gene: gene,exon,CDS,promoter
	Male Effect: -0.0715234460771011
	Female Effect: -

Male-specific eQTM regulation.

CpG Site	CpG Postion	Position to Gene	Effect Score	FDR	Cor.r	Cor.Pvalue	Cancer Type
cg20104776	chrX:141176991	gene,exon,CDS,promoter	-0.105215774288751	3.86235025240476e-05	-0.4869851628988379	3.680046817139443e-07	PAAD
cg00917018	chrX:141177364	promoter	-0.0657545567320079	7.57983957609857e-05	-0.33497169624926293	4.0960991770590613e-07	LUAD
cg09112156	chrX:141177074	gene,exon,promoter,UTR	-0.0746618227748657	1.26145925707971e-07	-0.4134027252900484	1.717068323702614e-10	STAD
cg14562990	chrX:141177441	promoter	-0.0770802072128468	1.37173939112712e-07	-0.41239843890145556	1.9192042492752758e-10	STAD
cg25870731	chrX:141176844	gene,exon,CDS,promoter	-0.070482713374659	9.22141947898088e-07	-0.3912297334802985	1.842325069799734e-09	STAD
cg20104776	chrX:141176991	gene,exon,CDS,promoter	-0.0577558958050777	2.32906322182451e-07	-0.38592227424456405	2.0706980881458338e-10	LIHC
cg20104776	chrX:141176991	gene,exon,CDS,promoter	-0.0897561147737711	6.45381968567203e-13	-0.4339790864950266	1.9400546179799568e-15	BLCA
cg00917018	chrX:141177364	promoter	-0.107097293867189	1.2809048463938e-10	-0.4161948880436006	8.706493061664182e-14	BLCA
cg27076487	chrX:141177179	promoter	-0.109769052264981	3.33971532045579e-10	-0.3968120847406921	6.052585938457978e-13	BLCA
cg20104776	chrX:141176991	gene,exon,CDS,promoter	-0.0715234460771011	3.79363500576414e-10	-0.3626634526638847	7.007072043710652e-13	HNSC

Female-specific eQTM regulation.

CpG Site

CpG Postion

Position to Gene

Effect Score

FDR

Cor.r

Cor.Pvalue

Cancer Type

Opposite sex-biased eQTM regulation.

CpG Site

CpG Postion

CpG Island

Position to Gene

Male Effect

Male FDR

Female Effect

Female FDR

Male Cor

Male P-value

Female Cor

Female P-value

Sex-biased Coding Gene

Cancer Type

Top

Sex-biased sQTL regulation of gene

Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).

sQTL

Description

Male-specific sQTL regulation.

ES ID

Skipped Exon

ORF Anno

SNP ID

SNP Info

SNP Position to ES

Effect Score

FDR

Cancer Type

Biased Type

Female-specific sQTL regulation.

ES ID

Skipped Exon

ORF Anno

SNP ID

SNP Info

SNP Position to ES

Effect Score

FDR

Cancer Type

Biased Type

Opposite sex-biased sQTL regulation.

ES ID

Skipped Exon

ORF Anno

SNP ID

SNP Info

SNP Position to ES

Male Effect

Male FDR

Female Effect

Female FDR

Cancer Type

Top

Sex-biased sQTM regulation of gene

Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).

sQTM

Description

Male-specific sQTM regulation.

EX ID

Skipped Exon

CPG Site

CPG Position

Position to EX Events

Effect Score

FDR

Cor.r

Cor.Pvalue

ORF_anno

Cancer Type

Female-specific sQTM regulation.

EX ID

Skipped Exon

CPG Site

CPG Position

Position to EX Events

Effect Score

FDR

Cor.r

Cor.Pvalue

ORF_anno

Cancer Type

Opposite sex-biased sQTM regulation.

EX ID

EX Info

Skipped Exon

CPG Site

CPG Position

CPG Island

Position to EX Events

Male Effect

Male FDR

Female Effect

Female FDR

Male Correlation

Male P-value

Female Correlation

Female P-value

ORF_anno

Cancer Type

Top

Related disease information of LDOC1

Diseases associated with this gene (DisGeNET).

Gene ID

Gene Symbol

Disease ID

Disease Name

Number of PMID

Source

	Gene summary
	Gene structure and Gene expression level
	Sex-biased somatic mutation
	DNA methylation with beta values in gene
	Exon skipping events with PSI in TCGA
	RNA A-to-I editing events in TCGA
	Sex-biased TF-Gene network of gene
	Sex-biased RBP-ES network of gene
	Sex-biased CeRNA regulation of gene
	Sex-biased eQTL regulation of gene
	Sex-biased eQTM regulation of gene
	Sex-biased sQTL regulation of gene
	Sex-biased sQTM regulation of gene
	Related disease information of gene