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Gene: ENSG00000180543 |
Summary for TSPYL5 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000180543 | Gene symbol | TSPYL5 |
| Gene name | TSPY like 5 | |
| HGNC | 29367 | |
| Entrez ID | 85453 | |
| Gene type | protein_coding | |
| Synonyms | TSPYL5|KIAA1750 | |
| UniProtAcc | Q86VY4 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for TSPYL5 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| TSPYL5 | 4.52e+02 | -1.20e+00 | 3.20e-01 | -3.70e+00 | 2.10e-04 | 5.20e-04 | HNSC |
| TSPYL5 | 8.63e+02 | 2.24e+00 | 7.11e-01 | 3.15e+00 | 1.64e-03 | 5.23e-03 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| TSPYL5 | 2.72e+03 | 1.13e+00 | 3.56e-01 | 3.17e+00 | 1.51e-03 | 3.30e-03 | LUSC |
| TSPYL5 | 1.66e+02 | -2.44e+00 | 4.00e-01 | -6.10e+00 | 1.05e-09 | 2.18e-08 | READ |
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Sex-biased somatic mutation for TSPYL5 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for TSPYL5 |
| Landscape of DNA methylation across multiple cancer types. |
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| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| GBM | cg22319311 | chr8:97278082 | CGI:chr8:97277376-97278176 | promoter | 3.87e-01 | 5.09e-01 | -2.22e+00 | 2.63e-02 | 3.98e-02 | -1.22e-01 |
| MESO | cg04917181 | chr8:97278001 | CGI:chr8:97277376-97278176 | promoter | 1.90e-01 | 3.05e-01 | -2.08e+00 | 3.78e-02 | 4.71e-02 | -1.16e-01 |
| MESO | cg15747595 | chr8:97277652 | CGI:chr8:97277376-97278176 | promoter,exon,CDS,gene body | 2.71e-01 | 3.88e-01 | -2.12e+00 | 3.38e-02 | 4.58e-02 | -1.17e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUAD | cg00032205 | chr8:97278144 | CGI:chr8:97277376-97278176 | promoter | 3.78e-01 | 2.74e-01 | 1.99e+00 | 4.69e-02 | 4.75e-02 | 1.04e-01 |
| THCA | cg09503853 | chr8:97278346 | CGI:chr8:97277376-97278176 | promoter | 8.03e-01 | 7.00e-01 | 2.70e+00 | 7.02e-03 | 1.28e-02 | 1.03e-01 |
| LUSC | cg18233405 | chr8:97277920 | CGI:chr8:97277376-97278176 | UTR,promoter,exon,gene body | 1.51e-01 | 1.84e-02 | 3.24e+00 | 1.21e-03 | 2.96e-03 | 1.33e-01 |
| LUSC | cg04917181 | chr8:97278001 | CGI:chr8:97277376-97278176 | promoter | 2.80e-01 | 2.88e-02 | 3.28e+00 | 1.04e-03 | 2.67e-03 | 2.51e-01 |
| LUSC | cg01569173 | chr8:97276682 | CGI:chr8:97277376-97278176 | promoter,exon,CDS,gene body | 7.27e-01 | 9.49e-01 | -4.19e+00 | 2.76e-05 | 5.26e-04 | -2.22e-01 |
| LUSC | cg15747595 | chr8:97277652 | CGI:chr8:97277376-97278176 | promoter,exon,CDS,gene body | 4.06e-01 | 2.36e-01 | 2.42e+00 | 1.55e-02 | 1.95e-02 | 1.70e-01 |
| COAD | cg22328208 | chr8:97277517 | CGI:chr8:97277376-97278176 | promoter,exon,CDS,gene body | 8.44e-01 | 7.18e-01 | 3.93e+00 | 8.51e-05 | 3.08e-04 | 1.26e-01 |
| BLCA | cg22328208 | chr8:97277517 | CGI:chr8:97277376-97278176 | promoter,exon,CDS,gene body | 5.89e-01 | 4.30e-01 | 2.23e+00 | 2.60e-02 | 3.01e-02 | 1.59e-01 |
| BLCA | cg23197859 | chr8:97278373 | CGI:chr8:97277376-97278176 | promoter | 7.36e-01 | 8.88e-01 | -2.23e+00 | 2.58e-02 | 2.99e-02 | -1.52e-01 |
| CHOL | cg00186701 | chr8:97278282 | CGI:chr8:97277376-97278176 | promoter | 5.86e-01 | 7.66e-01 | -2.43e+00 | 1.50e-02 | 2.65e-02 | -1.80e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg18233405 | chr8:97277920 | CGI:chr8:97277376-97278176 | UTR,promoter,exon,gene body | 1.75e-01 | 2.86e-02 | 6.82e+00 | 8.89e-12 | 2.54e-11 | 1.46e-01 |
| BRCA | cg04917181 | chr8:97278001 | CGI:chr8:97277376-97278176 | promoter | 2.61e-01 | 6.38e-02 | 6.70e+00 | 2.02e-11 | 5.62e-11 | 1.98e-01 |
| BRCA | cg22319311 | chr8:97278082 | CGI:chr8:97277376-97278176 | promoter | 2.62e-01 | 6.74e-02 | 6.03e+00 | 1.66e-09 | 3.96e-09 | 1.95e-01 |
| BRCA | cg22328208 | chr8:97277517 | CGI:chr8:97277376-97278176 | promoter,exon,CDS,gene body | 6.16e-01 | 4.56e-01 | 7.37e+00 | 1.70e-13 | 5.55e-13 | 1.61e-01 |
| BRCA | cg01569173 | chr8:97276682 | CGI:chr8:97277376-97278176 | promoter,exon,CDS,gene body | 7.64e-01 | 9.50e-01 | -1.26e+01 | 1.46e-36 | 5.59e-35 | -1.85e-01 |
| BRCA | cg15747595 | chr8:97277652 | CGI:chr8:97277376-97278176 | promoter,exon,CDS,gene body | 4.11e-01 | 2.23e-01 | 7.12e+00 | 1.11e-12 | 3.41e-12 | 1.88e-01 |
| BRCA | cg00032205 | chr8:97278144 | CGI:chr8:97277376-97278176 | promoter | 4.10e-01 | 2.12e-01 | 6.58e+00 | 4.65e-11 | 1.26e-10 | 1.98e-01 |
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Exon skipping events with PSI in TCGA for TSPYL5 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
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RNA A-to-I editing events in TCGA for TSPYL5 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for TSPYL5 |
| TFs related to TSPYL5. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| BRCA | DNMT1 | TSPYL5 | 3.59e+00 | 6.15e-03 | 4.96e+00 | 9.89e-01 | Female-biased |
| BRCA | EGR4 | TSPYL5 | 4.27e+00 | 1.14e-02 | 5.45e+00 | 9.87e-01 | Female-biased |
| BRCA | MYOD1 | TSPYL5 | 4.05e+00 | 8.93e-03 | 5.31e+00 | 9.89e-01 | Female-biased |
| BRCA | NR1H4 | TSPYL5 | 2.77e+00 | 1.71e-04 | 5.22e+00 | 9.97e-01 | Female-biased |
| BRCA | REST | TSPYL5 | 3.51e+00 | 2.08e-03 | 5.24e+00 | 9.95e-01 | Female-biased |
| BRCA | SALL4 | TSPYL5 | 2.21e+00 | 1.04e-04 | 4.77e+00 | 9.94e-01 | Female-biased |
| BRCA | TFAP4 | TSPYL5 | 3.31e+00 | 1.15e-03 | 5.23e+00 | 9.96e-01 | Female-biased |
| BRCA | ZBTB26 | TSPYL5 | 3.35e+00 | 7.77e-03 | 4.64e+00 | 9.85e-01 | Female-biased |
| BRCA | ZNF100 | TSPYL5 | 3.34e+00 | 5.28e-03 | 4.76e+00 | 9.88e-01 | Female-biased |
| BRCA | ZNF30 | TSPYL5 | 3.03e+00 | 6.40e-03 | 4.38e+00 | 9.81e-01 | Female-biased |
| BRCA | ZNF304 | TSPYL5 | 2.63e+00 | 2.17e-03 | 4.32e+00 | 9.84e-01 | Female-biased |
| BRCA | ZNF311 | TSPYL5 | 3.10e+00 | 1.86e-03 | 4.85e+00 | 9.93e-01 | Female-biased |
| BRCA | ZNF322 | TSPYL5 | 2.90e+00 | 8.03e-04 | 4.92e+00 | 9.95e-01 | Female-biased |
| BRCA | ZNF394 | TSPYL5 | 2.70e+00 | 3.13e-04 | 4.99e+00 | 9.96e-01 | Female-biased |
| BRCA | ZNF417 | TSPYL5 | 3.87e+00 | 3.10e-03 | 5.47e+00 | 9.95e-01 | Female-biased |
| BRCA | ZNF418 | TSPYL5 | 4.76e+00 | 9.95e-01 | 1.85e+00 | 4.73e-05 | Male-biased |
| BRCA | ZNF44 | TSPYL5 | 2.87e+00 | 1.43e-03 | 4.71e+00 | 9.92e-01 | Female-biased |
| BRCA | ZNF548 | TSPYL5 | 2.74e+00 | 1.44e-03 | 4.56e+00 | 9.90e-01 | Female-biased |
| BRCA | ZNF563 | TSPYL5 | 3.28e+00 | 1.03e-03 | 5.24e+00 | 9.96e-01 | Female-biased |
| BRCA | ZNF594 | TSPYL5 | 3.67e+00 | 1.42e-03 | 5.53e+00 | 9.97e-01 | Female-biased |
| BRCA | ZNF611 | TSPYL5 | 3.05e+00 | 6.35e-04 | 5.15e+00 | 9.96e-01 | Female-biased |
| BRCA | ZNF792 | TSPYL5 | 2.84e+00 | 3.02e-03 | 4.43e+00 | 9.86e-01 | Female-biased |
| BRCA | ZNF816 | TSPYL5 | 2.85e+00 | 1.91e-04 | 5.27e+00 | 9.97e-01 | Female-biased |
| BRCA | ZNF93 | TSPYL5 | 2.62e+00 | 1.13e-03 | 4.53e+00 | 9.90e-01 | Female-biased |
| CHOL | DNMT1 | TSPYL5 | 4.38e+00 | 9.93e-01 | 2.88e+00 | 1.10e-03 | Male-biased |
| CHOL | GATA2 | TSPYL5 | 4.22e+00 | 1.15e-02 | 5.12e+00 | 9.86e-01 | Female-biased |
| CHOL | NR1H4 | TSPYL5 | 4.33e+00 | 9.93e-01 | 2.40e+00 | 1.45e-04 | Male-biased |
| CHOL | SALL4 | TSPYL5 | 4.08e+00 | 9.90e-01 | 2.40e+00 | 4.57e-04 | Male-biased |
| CHOL | TFAP4 | TSPYL5 | 4.34e+00 | 9.88e-01 | 3.21e+00 | 5.31e-03 | Male-biased |
| CHOL | ZBTB26 | TSPYL5 | 4.32e+00 | 9.89e-01 | 3.12e+00 | 4.08e-03 | Male-biased |
| CHOL | ZNF100 | TSPYL5 | 4.56e+00 | 9.95e-01 | 2.95e+00 | 6.71e-04 | Male-biased |
| CHOL | ZNF180 | TSPYL5 | 4.32e+00 | 9.93e-01 | 2.21e+00 | 6.14e-05 | Male-biased |
| CHOL | ZNF30 | TSPYL5 | 4.48e+00 | 9.95e-01 | 2.62e+00 | 2.08e-04 | Male-biased |
| CHOL | ZNF304 | TSPYL5 | 4.39e+00 | 9.94e-01 | 2.19e+00 | 4.13e-05 | Male-biased |
| CHOL | ZNF311 | TSPYL5 | 4.52e+00 | 9.95e-01 | 2.57e+00 | 1.33e-04 | Male-biased |
| CHOL | ZNF322 | TSPYL5 | 4.18e+00 | 9.90e-01 | 2.84e+00 | 2.14e-03 | Male-biased |
| CHOL | ZNF394 | TSPYL5 | 4.22e+00 | 9.91e-01 | 2.67e+00 | 8.61e-04 | Male-biased |
| CHOL | ZNF417 | TSPYL5 | 4.63e+00 | 9.90e-01 | 3.53e+00 | 6.22e-03 | Male-biased |
| CHOL | ZNF418 | TSPYL5 | 3.09e+00 | 2.80e-05 | 5.30e+00 | 9.98e-01 | Female-biased |
| CHOL | ZNF44 | TSPYL5 | 4.42e+00 | 9.94e-01 | 2.63e+00 | 2.81e-04 | Male-biased |
| CHOL | ZNF519 | TSPYL5 | 4.38e+00 | 9.94e-01 | 2.47e+00 | 1.64e-04 | Male-biased |
| CHOL | ZNF548 | TSPYL5 | 4.38e+00 | 9.94e-01 | 2.33e+00 | 8.17e-05 | Male-biased |
| CHOL | ZNF563 | TSPYL5 | 4.29e+00 | 9.89e-01 | 3.09e+00 | 3.90e-03 | Male-biased |
| CHOL | ZNF571 | TSPYL5 | 4.28e+00 | 9.93e-01 | 2.51e+00 | 3.00e-04 | Male-biased |
| CHOL | ZNF594 | TSPYL5 | 4.56e+00 | 9.90e-01 | 3.41e+00 | 5.07e-03 | Male-biased |
| CHOL | ZNF611 | TSPYL5 | 4.58e+00 | 9.95e-01 | 2.45e+00 | 5.60e-05 | Male-biased |
| CHOL | ZNF615 | TSPYL5 | 4.26e+00 | 4.91e-03 | 5.38e+00 | 9.93e-01 | Female-biased |
| CHOL | ZNF792 | TSPYL5 | 4.64e+00 | 9.96e-01 | 2.37e+00 | 3.01e-05 | Male-biased |
| CHOL | ZNF816 | TSPYL5 | 4.44e+00 | 9.94e-01 | 2.69e+00 | 3.42e-04 | Male-biased |
| CHOL | ZNF93 | TSPYL5 | 4.38e+00 | 9.94e-01 | 2.47e+00 | 1.58e-04 | Male-biased |
| ESCA | DNMT1 | TSPYL5 | 5.00e+00 | 9.97e-01 | 3.31e+00 | 4.41e-05 | Male-biased |
| ESCA | NR1H4 | TSPYL5 | 4.43e+00 | 9.90e-01 | 3.53e+00 | 3.65e-03 | Male-biased |
| ESCA | SALL4 | TSPYL5 | 3.90e+00 | 9.81e-01 | 3.03e+00 | 4.14e-03 | Male-biased |
| ESCA | ZBTB26 | TSPYL5 | 4.32e+00 | 9.89e-01 | 3.42e+00 | 3.61e-03 | Male-biased |
| ESCA | ZNF100 | TSPYL5 | 4.60e+00 | 9.95e-01 | 3.08e+00 | 1.03e-04 | Male-biased |
| ESCA | ZNF30 | TSPYL5 | 4.21e+00 | 9.91e-01 | 2.51e+00 | 3.55e-05 | Male-biased |
| ESCA | ZNF304 | TSPYL5 | 3.84e+00 | 9.84e-01 | 2.32e+00 | 9.85e-05 | Male-biased |
| ESCA | ZNF311 | TSPYL5 | 4.48e+00 | 9.94e-01 | 2.98e+00 | 1.18e-04 | Male-biased |
| ESCA | ZNF44 | TSPYL5 | 4.37e+00 | 9.93e-01 | 3.09e+00 | 4.21e-04 | Male-biased |
| ESCA | ZNF548 | TSPYL5 | 4.01e+00 | 9.88e-01 | 2.67e+00 | 2.71e-04 | Male-biased |
| ESCA | ZNF611 | TSPYL5 | 4.72e+00 | 9.96e-01 | 3.11e+00 | 6.57e-05 | Male-biased |
| ESCA | ZNF792 | TSPYL5 | 4.11e+00 | 9.90e-01 | 2.45e+00 | 4.36e-05 | Male-biased |
| ESCA | ZNF816 | TSPYL5 | 4.38e+00 | 9.86e-01 | 3.60e+00 | 7.03e-03 | Male-biased |
| ESCA | ZNF93 | TSPYL5 | 3.97e+00 | 9.87e-01 | 2.72e+00 | 4.64e-04 | Male-biased |
| GBM | DNMT1 | TSPYL5 | 2.93e+00 | 5.97e-03 | 4.17e+00 | 9.83e-01 | Female-biased |
| GBM | NR1H4 | TSPYL5 | 3.23e+00 | 7.03e-03 | 4.43e+00 | 9.86e-01 | Female-biased |
| GBM | SALL4 | TSPYL5 | 2.80e+00 | 5.33e-03 | 4.09e+00 | 9.82e-01 | Female-biased |
| GBM | ZNF100 | TSPYL5 | 2.61e+00 | 3.73e-03 | 4.03e+00 | 9.82e-01 | Female-biased |
| GBM | ZNF311 | TSPYL5 | 2.69e+00 | 4.71e-03 | 4.02e+00 | 9.81e-01 | Female-biased |
| GBM | ZNF394 | TSPYL5 | 3.17e+00 | 7.65e-03 | 4.32e+00 | 9.84e-01 | Female-biased |
| GBM | ZNF44 | TSPYL5 | 2.69e+00 | 3.46e-03 | 4.15e+00 | 9.86e-01 | Female-biased |
| GBM | ZNF611 | TSPYL5 | 2.87e+00 | 3.87e-03 | 4.29e+00 | 9.88e-01 | Female-biased |
| GBM | ZNF816 | TSPYL5 | 3.28e+00 | 8.10e-03 | 4.41e+00 | 9.85e-01 | Female-biased |
| GBM | ZNF93 | TSPYL5 | 2.59e+00 | 3.52e-03 | 4.04e+00 | 9.83e-01 | Female-biased |
| LAML | NR1H4 | TSPYL5 | 3.30e+00 | 4.33e-03 | 4.41e+00 | 9.86e-01 | Female-biased |
| LAML | ZNF418 | TSPYL5 | 4.89e+00 | 9.95e-01 | 2.89e+00 | 1.14e-04 | Male-biased |
| LGG | DNMT1 | TSPYL5 | 4.79e+00 | 9.88e-01 | 4.26e+00 | 7.05e-03 | Male-biased |
| LGG | ZNF311 | TSPYL5 | 4.30e+00 | 9.80e-01 | 3.81e+00 | 8.75e-03 | Male-biased |
| LGG | ZNF611 | TSPYL5 | 4.55e+00 | 9.85e-01 | 4.05e+00 | 8.28e-03 | Male-biased |
| LGG | ZNF816 | TSPYL5 | 4.47e+00 | 9.83e-01 | 4.00e+00 | 9.42e-03 | Male-biased |
| MESO | NR1H4 | TSPYL5 | 3.28e+00 | 6.46e-03 | 4.70e+00 | 9.88e-01 | Female-biased |
| MESO | SALL4 | TSPYL5 | 2.80e+00 | 2.67e-03 | 4.46e+00 | 9.90e-01 | Female-biased |
| MESO | TFAP4 | TSPYL5 | 3.66e+00 | 1.36e-02 | 4.84e+00 | 9.82e-01 | Female-biased |
| MESO | ZNF180 | TSPYL5 | 2.44e+00 | 3.40e-03 | 4.02e+00 | 9.82e-01 | Female-biased |
| MESO | ZNF30 | TSPYL5 | 2.92e+00 | 7.06e-03 | 4.29e+00 | 9.83e-01 | Female-biased |
| MESO | ZNF304 | TSPYL5 | 2.66e+00 | 3.00e-03 | 4.29e+00 | 9.87e-01 | Female-biased |
| MESO | ZNF311 | TSPYL5 | 3.05e+00 | 6.41e-03 | 4.46e+00 | 9.86e-01 | Female-biased |
| MESO | ZNF322 | TSPYL5 | 3.25e+00 | 6.61e-03 | 4.65e+00 | 9.88e-01 | Female-biased |
| MESO | ZNF394 | TSPYL5 | 3.06e+00 | 4.28e-03 | 4.60e+00 | 9.90e-01 | Female-biased |
| MESO | ZNF418 | TSPYL5 | 4.20e+00 | 9.89e-01 | 2.35e+00 | 1.02e-03 | Male-biased |
| MESO | ZNF44 | TSPYL5 | 3.11e+00 | 6.09e-03 | 4.54e+00 | 9.87e-01 | Female-biased |
| MESO | ZNF548 | TSPYL5 | 2.87e+00 | 4.04e-03 | 4.41e+00 | 9.88e-01 | Female-biased |
| MESO | ZNF611 | TSPYL5 | 3.16e+00 | 4.97e-03 | 4.65e+00 | 9.89e-01 | Female-biased |
| MESO | ZNF792 | TSPYL5 | 2.80e+00 | 3.90e-03 | 4.35e+00 | 9.87e-01 | Female-biased |
| MESO | ZNF816 | TSPYL5 | 3.37e+00 | 4.06e-03 | 4.92e+00 | 9.92e-01 | Female-biased |
| MESO | ZNF93 | TSPYL5 | 2.88e+00 | 6.15e-03 | 4.29e+00 | 9.84e-01 | Female-biased |
| PAAD | ZNF594 | TSPYL5 | 4.64e+00 | 9.80e-01 | 3.88e+00 | 1.42e-02 | Male-biased |
| PCPG | DNMT1 | TSPYL5 | 2.90e+00 | 1.44e-04 | 4.60e+00 | 9.95e-01 | Female-biased |
| PCPG | ZBTB26 | TSPYL5 | 2.93e+00 | 1.72e-03 | 4.11e+00 | 9.87e-01 | Female-biased |
| PCPG | ZNF100 | TSPYL5 | 2.84e+00 | 4.94e-04 | 4.28e+00 | 9.91e-01 | Female-biased |
| PCPG | ZNF311 | TSPYL5 | 2.69e+00 | 1.40e-03 | 3.91e+00 | 9.83e-01 | Female-biased |
| THYM | ZNF418 | TSPYL5 | 5.06e+00 | 8.69e-03 | 5.79e+00 | 9.90e-01 | Female-biased |
| TSPYL5 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for TSPYL5 |
| RBPs related to ES in TSPYL5. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| TSPYL5 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs17461454 | chr8:100860368:G:A | - | 0.216841954395705 | 0.0243550870428449 | KIRP | Female-baised eQTL |
| rs77917366 | chr8:105540657:C:G | - | 0.255488971745748 | 0.0336108147951623 | KIRP | Female-baised eQTL |
| rs72669868 | chr8:95777601:C:T | - | 0.238960196551039 | 0.0446030971727007 | KIRP | Female-baised eQTL |
| rs79744793 | chr8:88332720:A:G | - | 0.213665262985106 | 0.0324140053851154 | STAD | Female-baised eQTL |
| rs1470322 | chr8:91906959:T:G | - | -0.060253706002613 | 0.00830098481476401 | LUAD | Female-baised eQTL |
| rs1443557 | chr8:91883213:A:T | - | -0.0584598944712554 | 0.00934329070989765 | LUAD | Female-baised eQTL |
| rs1443561 | chr8:91916441:T:C | - | -0.0612536306813923 | 0.0101732397427515 | LUAD | Female-baised eQTL |
| rs6991800 | chr8:91918915:T:C | - | -0.0612536306813923 | 0.0101732397427515 | LUAD | Female-baised eQTL |
| rs3853593 | chr8:91926706:T:C | - | -0.0613370905101224 | 0.0104632720953963 | LUAD | Female-baised eQTL |
| rs4734934 | chr8:91921206:C:T | - | -0.0608901863123994 | 0.010936092385105 | LUAD | Female-baised eQTL |
| rs1031115 | chr8:91921385:A:G | - | -0.0608901863123994 | 0.010936092385105 | LUAD | Female-baised eQTL |
| rs1443560 | chr8:91908863:A:T | - | -0.0589061777565334 | 0.0115876336777038 | LUAD | Female-baised eQTL |
| rs7825946 | chr8:91909639:C:A | - | -0.058857884430329 | 0.0117164356307739 | LUAD | Female-baised eQTL |
| rs2008073 | chr8:91910152:C:T | - | -0.0588753200371104 | 0.0118695082148202 | LUAD | Female-baised eQTL |
| rs4329248 | chr8:102191527:T:C | - | 0.084413936379901 | 0.012194813564389 | LUAD | Female-baised eQTL |
| rs11786397 | chr8:102192744:A:G | - | 0.084413936379901 | 0.012194813564389 | LUAD | Female-baised eQTL |
| rs111839194 | chr8:102194165:A:C | - | 0.084413936379901 | 0.012194813564389 | LUAD | Female-baised eQTL |
| rs57901015 | chr8:102195882:A:C | - | 0.084413936379901 | 0.012194813564389 | LUAD | Female-baised eQTL |
| rs77770393 | chr8:102196191:G:A | - | 0.084413936379901 | 0.012194813564389 | LUAD | Female-baised eQTL |
| rs10111529 | chr8:91913201:A:G | - | -0.0606366173774519 | 0.0122233652879492 | LUAD | Female-baised eQTL |
| rs1443563 | chr8:91930207:T:C | - | -0.0600174379263662 | 0.0135980307498242 | LUAD | Female-baised eQTL |
| rs10504913 | chr8:91931188:T:C | - | -0.0600174379263662 | 0.0135980307498242 | LUAD | Female-baised eQTL |
| rs1838183 | chr8:91933156:T:C | - | -0.0583327503018893 | 0.0138589153285589 | LUAD | Female-baised eQTL |
| rs4734923 | chr8:91884263:G:T | - | -0.0573558813677494 | 0.0139402190030301 | LUAD | Female-baised eQTL |
| rs2008246 | chr8:91910226:G:T | - | -0.0581304735412619 | 0.0143158165287207 | LUAD | Female-baised eQTL |
| rs3863252 | chr8:91928810:C:T | - | -0.0570496689893306 | 0.0172314402153045 | LUAD | Female-baised eQTL |
| rs13250762 | chr8:94975342:A:G | - | 0.0670606363000335 | 0.0204072567389307 | LUAD | Female-baised eQTL |
| rs1838182 | chr8:91909258:G:A | - | -0.0548290367350104 | 0.0237399832254601 | LUAD | Female-baised eQTL |
| rs72664683 | chr8:95238319:T:G | - | 0.0594986932610108 | 0.0238663394536643 | LUAD | Female-baised eQTL |
| rs71532343 | chr8:95064585:T:C | - | 0.0680282510344362 | 0.0244693088009055 | LUAD | Female-baised eQTL |
| rs35518242 | chr8:95066867:C:T | - | 0.0680282510344362 | 0.0244693088009055 | LUAD | Female-baised eQTL |
| rs10103170 | chr8:91897477:G:A | - | -0.0558339472789914 | 0.0251779268575595 | LUAD | Female-baised eQTL |
| rs34901613 | chr8:95092878:C:T | - | 0.0670925190469843 | 0.0259263996520864 | LUAD | Female-baised eQTL |
| rs11784746 | chr8:95088575:C:T | - | 0.0667628876342239 | 0.02622279577627 | LUAD | Female-baised eQTL |
| rs117684233 | chr8:95089052:G:A | - | 0.0667628876342239 | 0.02622279577627 | LUAD | Female-baised eQTL |
| rs11781447 | chr8:95090431:C:T | - | 0.0667628876342239 | 0.02622279577627 | LUAD | Female-baised eQTL |
| rs13274368 | chr8:95086819:G:A | - | 0.0667897467510684 | 0.0266463326477397 | LUAD | Female-baised eQTL |
| rs13251759 | chr8:95087399:T:C | - | 0.0664734397459739 | 0.0269181936917585 | LUAD | Female-baised eQTL |
| rs13251032 | chr8:95087766:C:T | - | 0.0664734397459739 | 0.0269181936917585 | LUAD | Female-baised eQTL |
| rs7012686 | chr8:91913323:C:T | - | -0.0575171288584066 | 0.0269268850204526 | LUAD | Female-baised eQTL |
| rs11775502 | chr8:91912495:G:A | - | -0.0571665298271188 | 0.0275394780912583 | LUAD | Female-baised eQTL |
| rs4734927 | chr8:91894151:T:C | - | -0.056928035353004 | 0.0278064401408104 | LUAD | Female-baised eQTL |
| rs10087764 | chr8:91910701:G:A | - | -0.0540036605429297 | 0.0294594374867469 | LUAD | Female-baised eQTL |
| rs28375319 | chr8:91934568:C:T | - | -0.0548493174238073 | 0.0326664385412346 | LUAD | Female-baised eQTL |
| rs13279040 | chr8:95068161:A:C | - | 0.0640824242930678 | 0.0383804744317733 | LUAD | Female-baised eQTL |
| rs216981 | chr8:89616419:T:G | - | 0.0795040908365408 | 0.0389903829549083 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000180543 |
| CpG Site: cg09503853 | |
| Position to Gene: promoter | |
| Male Effect: -0.317915117125659 | |
| Female Effect: - | |
 | Gene ID: ENSG00000180543 |
| CpG Site: cg09503853 | |
| Position to Gene: promoter | |
| Male Effect: -0.216989748585355 | |
| Female Effect: - | |
 | Gene ID: ENSG00000180543 |
| CpG Site: cg22328208 | |
| Position to Gene: gene,exon,CDS,promoter | |
| Male Effect: -0.2906693313964 | |
| Female Effect: - | |
 | Gene ID: ENSG00000180543 |
| CpG Site: cg00186701 | |
| Position to Gene: promoter | |
| Male Effect: -0.311799221468225 | |
| Female Effect: - | |
 | Gene ID: ENSG00000180543 |
| CpG Site: cg09503853 | |
| Position to Gene: promoter | |
| Male Effect: -0.311799221468225 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg09503853 | chr8:97278346 | promoter | -0.317915117125659 | 5.23743443501461e-05 | -0.3237840836889459 | 7.743563642047056e-07 | LUAD |
| cg09503853 | chr8:97278346 | promoter | -0.216989748585355 | 6.61831041528972e-09 | -0.4352094339274168 | 1.3961615468775896e-11 | STAD |
| cg22328208 | chr8:97277517 | gene,exon,CDS,promoter | -0.2906693313964 | 1.12533640520616e-07 | -0.4138904835360179 | 1.626504323697576e-10 | STAD |
| cg00186701 | chr8:97278282 | promoter | -0.311799221468225 | 4.53536152688163e-27 | -0.5543040134560466 | 4.996914850310579e-31 | HNSC |
| cg09503853 | chr8:97278346 | promoter | -0.311799221468225 | 4.53536152688163e-27 | -0.5543040134560466 | 4.996914850310579e-31 | HNSC |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of TSPYL5 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
