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Gene: ENSG00000178996 |
Summary for SNX18 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000178996 | Gene symbol | SNX18 |
| Gene name | sorting nexin 18 | |
| HGNC | 19245 | |
| Entrez ID | 112574 | |
| Gene type | protein_coding | |
| Synonyms | SNX18|SH3PX2|SH3PXD3B | |
| UniProtAcc | Q96RF0 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for SNX18 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Top |
Sex-biased somatic mutation for SNX18 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for SNX18 |
| Landscape of DNA methylation across multiple cancer types. |
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| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| ACC | cg18373318 | chr5:54517334 | CGI:chr5:54517549-54519476 | promoter | 2.17e-01 | 3.26e-01 | -2.15e+00 | 3.17e-02 | 4.23e-02 | -1.09e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUSC | cg16358034 | chr5:54519473 | CGI:chr5:54517549-54519476 | promoter,exon,CDS,gene body | 8.10e-01 | 9.78e-01 | -2.75e+00 | 5.95e-03 | 9.30e-03 | -1.68e-01 |
| LUSC | cg08544436 | chr5:54518795 | CGI:chr5:54517549-54519476 | promoter,exon,CDS,gene body | 3.98e-01 | 5.52e-01 | -3.16e+00 | 1.57e-03 | 3.54e-03 | -1.55e-01 |
| LUSC | cg21995347 | chr5:54519061 | CGI:chr5:54517549-54519476 | promoter,exon,CDS,gene body | 7.38e-01 | 8.64e-01 | -2.82e+00 | 4.78e-03 | 7.89e-03 | -1.26e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg16358034 | chr5:54519473 | CGI:chr5:54517549-54519476 | promoter,exon,CDS,gene body | 8.92e-01 | 7.77e-01 | 1.01e+01 | 3.36e-24 | 2.65e-23 | 1.15e-01 |
| BRCA | cg08544436 | chr5:54518795 | CGI:chr5:54517549-54519476 | promoter,exon,CDS,gene body | 5.43e-01 | 3.50e-01 | 9.73e+00 | 2.36e-22 | 1.56e-21 | 1.92e-01 |
| LUAD | cg16358034 | chr5:54519473 | CGI:chr5:54517549-54519476 | promoter,exon,CDS,gene body | 8.12e-01 | 9.72e-01 | -1.99e+00 | 4.66e-02 | 4.74e-02 | -1.60e-01 |
Top |
Exon skipping events with PSI in TCGA for SNX18 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for SNX18 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for SNX18 |
| TFs related to SNX18. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| BLCA | ALX1 | SNX18 | 5.27e+00 | 1.70e-02 | 6.00e+00 | 9.82e-01 | Female-biased |
| BLCA | ZNF354B | SNX18 | 5.05e+00 | 1.34e-02 | 5.83e+00 | 9.86e-01 | Female-biased |
| SNX18 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for SNX18 |
| RBPs related to ES in SNX18. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| SNX18 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs13172381 | chr5:62666325:T:A | - | 0.19088232457103 | 0.0150596089195708 | GBM | Female-baised eQTL |
| rs72764398 | chr5:63712280:G:A | - | 0.220583822483189 | 0.0312406454662996 | GBM | Female-baised eQTL |
| rs7725624 | chr5:63714898:C:A | - | 0.220583822483189 | 0.0312406454662996 | GBM | Female-baised eQTL |
| rs7726949 | chr5:63723437:T:C | - | 0.220318416253355 | 0.042214779569972 | GBM | Female-baised eQTL |
| rs139547615 | chr5:57014969:G:A | - | 0.266180492715693 | 0.0250970257539554 | KIRP | Female-baised eQTL |
| rs13355337 | chr5:50347826:G:A | - | 0.184873774457194 | 0.037104488180213 | KIRP | Female-baised eQTL |
| rs10471787 | chr5:50350841:G:A | - | 0.184873774457194 | 0.037104488180213 | KIRP | Female-baised eQTL |
| rs12332293 | chr5:50350918:A:T | - | 0.184873774457194 | 0.037104488180213 | KIRP | Female-baised eQTL |
| rs61628676 | chr5:50307352:G:T | - | 0.183958889405929 | 0.0401121390418428 | KIRP | Female-baised eQTL |
| rs6880021 | chr5:50308809:G:A | - | 0.183958889405929 | 0.0401121390418428 | KIRP | Female-baised eQTL |
| rs185214519 | chr5:45349140:A:T | - | 0.176665945821682 | 0.00575552510573515 | BLCA | Female-baised eQTL |
| rs6861150 | chr5:45336687:T:A | - | 0.176781766284831 | 0.00582311014155771 | BLCA | Female-baised eQTL |
| rs116095611 | chr5:59013492:A:G | - | 0.190949800305157 | 0.0119246826868619 | BLCA | Female-baised eQTL |
| rs146209337 | chr5:59014901:C:T | - | 0.190949800305157 | 0.0119246826868619 | BLCA | Female-baised eQTL |
| rs75971028 | chr5:59019964:T:C | - | 0.190949800305157 | 0.0119246826868619 | BLCA | Female-baised eQTL |
| rs1075641 | chr5:59023107:G:A | - | 0.190949800305157 | 0.0119246826868619 | BLCA | Female-baised eQTL |
| rs1075640 | chr5:59023144:C:T | - | 0.190949800305157 | 0.0119246826868619 | BLCA | Female-baised eQTL |
| rs141986779 | chr5:59029403:C:T | - | 0.190949800305157 | 0.0119246826868619 | BLCA | Female-baised eQTL |
| rs2343698 | chr5:62076073:G:A | - | 0.178984110487271 | 0.0165919387455088 | BLCA | Female-baised eQTL |
| rs10068993 | chr5:62078115:C:T | - | 0.178984110487271 | 0.0165919387455088 | BLCA | Female-baised eQTL |
| rs58941344 | chr5:62079064:C:T | - | 0.178984110487271 | 0.0165919387455088 | BLCA | Female-baised eQTL |
| rs55788021 | chr5:62079503:C:T | - | 0.178984110487271 | 0.0165919387455088 | BLCA | Female-baised eQTL |
| rs73760549 | chr5:62082006:T:A | - | 0.178984110487271 | 0.0165919387455088 | BLCA | Female-baised eQTL |
| rs10066330 | chr5:62082266:C:A | - | 0.178984110487271 | 0.0165919387455088 | BLCA | Female-baised eQTL |
| rs6872868 | chr5:62084357:A:T | - | 0.178984110487271 | 0.0165919387455088 | BLCA | Female-baised eQTL |
| rs111567606 | chr5:59010745:A:C | - | 0.189332179545948 | 0.0173363937387516 | BLCA | Female-baised eQTL |
| rs3087748 | chr5:59016442:G:A | - | 0.189332179545948 | 0.0173363937387516 | BLCA | Female-baised eQTL |
| rs78165411 | chr5:59017543:C:T | - | 0.189332179545948 | 0.0173363937387516 | BLCA | Female-baised eQTL |
| rs78778448 | chr5:59019283:C:T | - | 0.189332179545948 | 0.0173363937387516 | BLCA | Female-baised eQTL |
| rs10940639 | chr5:59028010:A:G | - | 0.189332179545948 | 0.0173363937387516 | BLCA | Female-baised eQTL |
| rs12332696 | chr5:45392583:C:T | - | 0.131957029796548 | 0.0197571551182689 | BLCA | Female-baised eQTL |
| rs6874677 | chr5:45393450:G:C | - | 0.131946474620456 | 0.0206831285400806 | BLCA | Female-baised eQTL |
| rs3923055 | chr5:45391821:C:G | - | 0.130909411490574 | 0.021241158106529 | BLCA | Female-baised eQTL |
| rs1353747 | chr5:59041654:T:G | - | 0.188788639188839 | 0.0231358173441488 | BLCA | Female-baised eQTL |
| rs1553113 | chr5:59042610:A:C | - | 0.188788639188839 | 0.0231358173441488 | BLCA | Female-baised eQTL |
| rs1498608 | chr5:59047240:T:A | - | 0.188433197265602 | 0.023569159416141 | BLCA | Female-baised eQTL |
| rs16889126 | chr5:59050311:C:T | - | 0.188433197265602 | 0.023569159416141 | BLCA | Female-baised eQTL |
| rs7709262 | chr5:45341942:A:G | - | 0.122786896118363 | 0.0375609751861277 | BLCA | Female-baised eQTL |
| rs1501362 | chr5:45378105:C:T | - | 0.122786896118363 | 0.0375609751861277 | BLCA | Female-baised eQTL |
| rs6451798 | chr5:45387752:C:T | - | 0.122786896118363 | 0.0375609751861277 | BLCA | Female-baised eQTL |
| rs6874127 | chr5:45305513:A:G | - | 0.121406944232343 | 0.0394514403214897 | BLCA | Female-baised eQTL |
| rs13179496 | chr5:45392440:A:T | - | 0.127908010606402 | 0.0423887547971428 | BLCA | Female-baised eQTL |
| rs7721148 | chr5:62081486:T:C | - | 0.164102274680426 | 0.0428274672257771 | BLCA | Female-baised eQTL |
| rs17364351 | chr5:62082994:C:G | - | 0.164102274680426 | 0.0428274672257771 | BLCA | Female-baised eQTL |
| rs10045420 | chr5:45393652:G:C | - | 0.127884133754091 | 0.0442655428655088 | BLCA | Female-baised eQTL |
| rs6870682 | chr5:62096344:A:G | - | 0.15585782939155 | 0.0443070798660263 | BLCA | Female-baised eQTL |
| rs113966623 | chr5:45351783:T:C | - | 0.120427964986497 | 0.0469596887133844 | BLCA | Female-baised eQTL |
| rs2910580 | chr5:58232059:T:A | - | -0.0407144102038974 | 0.00842089042148097 | LUAD | Female-baised eQTL |
| rs2964199 | chr5:58236948:T:C | - | -0.0429675094187712 | 0.00865784998633637 | LUAD | Female-baised eQTL |
| rs11743591 | chr5:53477032:G:C | - | 0.0915326991393772 | 0.00926695189898019 | LUAD | Female-baised eQTL |
| rs71592630 | chr5:53479853:A:G | - | 0.091408207240411 | 0.00956365937265572 | LUAD | Female-baised eQTL |
| rs37500 | chr5:58291961:C:T | - | -0.0397001428315306 | 0.0127037190062952 | LUAD | Female-baised eQTL |
| rs37497 | chr5:58292729:A:G | - | -0.0397001428315306 | 0.0127037190062952 | LUAD | Female-baised eQTL |
| rs43217 | chr5:58282210:A:G | - | -0.0382457968385842 | 0.021999163731993 | LUAD | Female-baised eQTL |
| rs37519 | chr5:58284264:A:G | - | -0.0382457968385842 | 0.021999163731993 | LUAD | Female-baised eQTL |
| rs37487 | chr5:58296935:T:A | - | -0.0394398217057213 | 0.0237479742898755 | LUAD | Female-baised eQTL |
| rs37521 | chr5:58281636:C:T | - | -0.0376950403251422 | 0.0265133205805598 | LUAD | Female-baised eQTL |
| rs12657950 | chr5:62644742:C:T | - | 0.0610696226205626 | 0.0386834246655408 | LUAD | Female-baised eQTL |
| rs246114 | chr5:58340425:A:C | - | -0.0741425847068177 | 0.0394177857112767 | LUAD | Female-baised eQTL |
| rs245296 | chr5:58344744:T:C | - | -0.0741425847068177 | 0.0394177857112767 | LUAD | Female-baised eQTL |
| rs13154277 | chr5:59188971:G:A | - | 0.0609228934247319 | 0.0419541197882378 | LUAD | Female-baised eQTL |
| rs1551564 | chr5:59438336:A:G | - | -0.0355409548161497 | 0.0451340455833935 | LUAD | Female-baised eQTL |
| rs154671 | chr5:58334345:T:C | - | -0.0643806427742385 | 0.0490289382583754 | LUAD | Female-baised eQTL |
| rs2052547 | chr5:58240929:A:C | - | -0.0686415835670248 | 0.0499735504010482 | LUAD | Female-baised eQTL |
| rs2964195 | chr5:58244816:C:G | - | -0.0686415835670248 | 0.0499735504010482 | LUAD | Female-baised eQTL |
| rs6870949 | chr5:52890684:T:C | - | 0.0684243204414251 | 0.0427240452251902 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs12187520 | chr5:63820724:C:G | - | 0.0567374049201812 | 0.0468519235199465 | KIRC | Male-baised eQTL |
| rs9637769 | chr5:52940023:C:T | - | 0.0831458232977334 | 0.0299995809762102 | BLCA | Male-baised eQTL |
| rs6877927 | chr5:59358091:T:C | - | 0.0744866281201535 | 0.0349359273011351 | BLCA | Male-baised eQTL |
| rs17315606 | chr5:57627086:A:G | - | 0.122210730979629 | 1.83716148551586e-05 | COAD | Male-baised eQTL |
| rs76637350 | chr5:59069036:G:A | - | 0.0854086616771974 | 4.99854282098574e-05 | COAD | Male-baised eQTL |
| rs2041400 | chr5:57625540:A:C | - | 0.113902154952497 | 7.00240925870414e-05 | COAD | Male-baised eQTL |
| rs75932991 | chr5:59005520:C:T | - | 0.150530853111854 | 0.000155441549017581 | COAD | Male-baised eQTL |
| rs55860205 | chr5:57606430:G:C | - | 0.108843481038521 | 0.000185056290601252 | COAD | Male-baised eQTL |
| rs17315098 | chr5:57607254:C:T | - | 0.108843481038521 | 0.000185056290601252 | COAD | Male-baised eQTL |
| rs11949006 | chr5:57608536:C:T | - | 0.108843481038521 | 0.000185056290601252 | COAD | Male-baised eQTL |
| rs76538567 | chr5:57610141:T:G | - | 0.108843481038521 | 0.000185056290601252 | COAD | Male-baised eQTL |
| rs17315160 | chr5:57611418:C:T | - | 0.108843481038521 | 0.000185056290601252 | COAD | Male-baised eQTL |
| rs75703828 | chr5:57614891:G:A | - | 0.108843481038521 | 0.000185056290601252 | COAD | Male-baised eQTL |
| rs11953114 | chr5:57608504:T:C | - | 0.108563731921778 | 0.000199820243147576 | COAD | Male-baised eQTL |
| rs1033108 | chr5:50327764:A:G | - | 0.0716948611431318 | 0.000302133097769666 | COAD | Male-baised eQTL |
| rs11739293 | chr5:59077110:C:T | - | 0.0743003937299314 | 0.000321959346686196 | COAD | Male-baised eQTL |
| rs28555377 | chr5:59072615:C:T | - | 0.0743627840668892 | 0.000325954630787887 | COAD | Male-baised eQTL |
| rs12654005 | chr5:59075011:T:G | - | 0.0741434278702933 | 0.000337479593186172 | COAD | Male-baised eQTL |
| rs1391649 | chr5:59080179:A:C | - | 0.0735897237260129 | 0.000363243469024457 | COAD | Male-baised eQTL |
| rs10056112 | chr5:57605998:T:C | - | 0.105351570659514 | 0.000368932612779893 | COAD | Male-baised eQTL |
| rs10078580 | chr5:57606620:C:G | - | 0.105351570659514 | 0.000368932612779893 | COAD | Male-baised eQTL |
| rs2910642 | chr5:59100284:A:G | - | 0.0724708378506094 | 0.000403745325623954 | COAD | Male-baised eQTL |
| rs2968009 | chr5:59055780:G:A | - | 0.0742715561826465 | 0.000418562552854302 | COAD | Male-baised eQTL |
| rs16879124 | chr5:51718363:G:A | - | 0.145928878999708 | 0.000460333312845676 | COAD | Male-baised eQTL |
| rs1435071 | chr5:59981945:G:A | - | 0.0659038861285038 | 0.000646099728716788 | COAD | Male-baised eQTL |
| rs13178315 | chr5:59075768:T:C | - | 0.0716718906990142 | 0.000669609350281537 | COAD | Male-baised eQTL |
| rs13189156 | chr5:53456412:A:C | - | 0.0701632699354138 | 0.000825105406684368 | COAD | Male-baised eQTL |
| rs16891858 | chr5:63453919:G:T | - | 0.067558549602465 | 0.00131922983413372 | COAD | Male-baised eQTL |
| rs10940639 | chr5:59028010:A:G | - | 0.125065406904062 | 0.00133609483876302 | COAD | Male-baised eQTL |
| rs141986779 | chr5:59029403:C:T | - | 0.124045932953796 | 0.00159543178843905 | COAD | Male-baised eQTL |
| rs1075641 | chr5:59023107:G:A | - | 0.12250329657549 | 0.00170593243823499 | COAD | Male-baised eQTL |
| rs1075640 | chr5:59023144:C:T | - | 0.121411093434134 | 0.00173543550745155 | COAD | Male-baised eQTL |
| rs111567606 | chr5:59010745:A:C | - | 0.121974322317857 | 0.00180863626175934 | COAD | Male-baised eQTL |
| rs3087748 | chr5:59016442:G:A | - | 0.121974322317857 | 0.00180863626175934 | COAD | Male-baised eQTL |
| rs78165411 | chr5:59017543:C:T | - | 0.121974322317857 | 0.00180863626175934 | COAD | Male-baised eQTL |
| rs78778448 | chr5:59019283:C:T | - | 0.121974322317857 | 0.00180863626175934 | COAD | Male-baised eQTL |
| rs116095611 | chr5:59013492:A:G | - | 0.119518465024179 | 0.00227425542096347 | COAD | Male-baised eQTL |
| rs146209337 | chr5:59014901:C:T | - | 0.119518465024179 | 0.00227425542096347 | COAD | Male-baised eQTL |
| rs75971028 | chr5:59019964:T:C | - | 0.119518465024179 | 0.00227425542096347 | COAD | Male-baised eQTL |
| rs696199 | chr5:54016088:G:A | - | -0.072233341275024 | 0.00263863958102286 | COAD | Male-baised eQTL |
| rs929820 | chr5:59097505:G:A | - | 0.0628339085026688 | 0.0032947287988164 | COAD | Male-baised eQTL |
| rs4700291 | chr5:56365632:A:T | - | 0.0950037647361022 | 0.00444748709187412 | COAD | Male-baised eQTL |
| rs1353749 | chr5:59083482:A:G | - | 0.061846808154158 | 0.00637627262659917 | COAD | Male-baised eQTL |
| rs60960804 | chr5:56358472:G:A | - | 0.0910794240904405 | 0.00648611800436211 | COAD | Male-baised eQTL |
| rs10069751 | chr5:56049520:G:T | - | 0.0641771786950274 | 0.00668916130413793 | COAD | Male-baised eQTL |
| rs2455377 | chr5:56624864:C:T | - | 0.0574836461926402 | 0.00720838969286107 | COAD | Male-baised eQTL |
| rs7716272 | chr5:51227535:G:A | - | -0.0576194148065399 | 0.00776102256997605 | COAD | Male-baised eQTL |
| rs62360646 | chr5:56356707:C:T | - | 0.0902934237088533 | 0.00786302034403281 | COAD | Male-baised eQTL |
| rs1148035 | chr5:55902051:G:A | - | 0.0590592973123825 | 0.00796844801834964 | COAD | Male-baised eQTL |
| rs12658506 | chr5:57321750:G:C | - | 0.0982491039762157 | 0.00939192575119476 | COAD | Male-baised eQTL |
| rs55772472 | chr5:63297796:A:G | - | 0.075349860646952 | 0.0123797019857285 | COAD | Male-baised eQTL |
| rs11950693 | chr5:56352157:G:A | - | 0.0846309585117313 | 0.0129653308838396 | COAD | Male-baised eQTL |
| rs10061553 | chr5:59056383:C:T | - | 0.0623625749164292 | 0.0135705903022486 | COAD | Male-baised eQTL |
| rs55886081 | chr5:63290967:G:T | - | 0.0741974657905183 | 0.0144978970742617 | COAD | Male-baised eQTL |
| rs697100 | chr5:54021227:T:C | - | -0.062268817644489 | 0.0147285944411994 | COAD | Male-baised eQTL |
| rs2675374 | chr5:58838766:C:T | - | -0.0580812192731511 | 0.0147665633613857 | COAD | Male-baised eQTL |
| rs1389843 | chr5:63289403:C:T | - | 0.0729684826978996 | 0.0157136896187443 | COAD | Male-baised eQTL |
| rs12522991 | chr5:52205316:T:C | - | -0.0561054420081512 | 0.0166837848029506 | COAD | Male-baised eQTL |
| rs112121220 | chr5:63301141:C:T | - | 0.0736033764137953 | 0.018778705859162 | COAD | Male-baised eQTL |
| rs12519287 | chr5:57757742:A:G | - | -0.0553826421071743 | 0.0201013194220484 | COAD | Male-baised eQTL |
| rs299905 | chr5:58902066:G:A | - | 0.060478398878583 | 0.021802464896304 | COAD | Male-baised eQTL |
| rs697105 | chr5:54020441:A:G | - | -0.0599911782673137 | 0.0220598114904507 | COAD | Male-baised eQTL |
| rs697102 | chr5:54020796:G:A | - | -0.0599911782673137 | 0.0220598114904507 | COAD | Male-baised eQTL |
| rs13157802 | chr5:64541444:C:T | - | 0.0921479557964211 | 0.0239963695438674 | COAD | Male-baised eQTL |
| rs697108 | chr5:54008521:C:T | - | -0.0637573263742466 | 0.0267754502902644 | COAD | Male-baised eQTL |
| rs1353257 | chr5:64065890:C:T | - | 0.0750231954691453 | 0.0272159985943945 | COAD | Male-baised eQTL |
| rs1694056 | chr5:53981083:A:T | - | -0.0574624197111967 | 0.0274492324233536 | COAD | Male-baised eQTL |
| rs4865662 | chr5:51403718:A:G | - | -0.0534375440785702 | 0.0280208026762368 | COAD | Male-baised eQTL |
| rs6449622 | chr5:51413535:C:G | - | -0.053488054309381 | 0.0281405840850655 | COAD | Male-baised eQTL |
| rs6890519 | chr5:50696717:C:A | - | -0.0770590719738027 | 0.0312331831259396 | COAD | Male-baised eQTL |
| rs293007 | chr5:58729069:A:G | - | -0.0486730650553218 | 0.0344349847068278 | COAD | Male-baised eQTL |
| rs1067530 | chr5:54005709:G:A | - | -0.0614887195497182 | 0.0348908311097491 | COAD | Male-baised eQTL |
| rs10454820 | chr5:51422935:G:A | - | -0.0519940603523084 | 0.0350226226508416 | COAD | Male-baised eQTL |
| rs9291770 | chr5:51423574:T:G | - | -0.0519940603523084 | 0.0350226226508416 | COAD | Male-baised eQTL |
| rs4865664 | chr5:51426404:A:C | - | -0.0519940603523084 | 0.0350226226508416 | COAD | Male-baised eQTL |
| rs10066455 | chr5:51425908:G:A | - | -0.0517934751173569 | 0.0363594123078552 | COAD | Male-baised eQTL |
| rs1694055 | chr5:53980738:G:A | - | -0.0555287242510903 | 0.0380545881628037 | COAD | Male-baised eQTL |
| rs697109 | chr5:54007986:C:G | - | -0.0604183300385078 | 0.0385290003859964 | COAD | Male-baised eQTL |
| rs17738076 | chr5:57478614:G:T | - | 0.0499004177639423 | 0.0393393954282044 | COAD | Male-baised eQTL |
| rs4865666 | chr5:51441795:A:T | - | -0.0517974743529124 | 0.0398802437174682 | COAD | Male-baised eQTL |
| rs28664909 | chr5:51410665:G:A | - | -0.0522406723558752 | 0.0399448617057163 | COAD | Male-baised eQTL |
| rs787544 | chr5:53977512:G:T | - | -0.0548279097364595 | 0.0403479189485699 | COAD | Male-baised eQTL |
| rs986714 | chr5:51525504:A:T | - | -0.0530690217817305 | 0.0404671597283825 | COAD | Male-baised eQTL |
| rs697101 | chr5:54020812:G:A | - | -0.0557381922488846 | 0.0416603684590545 | COAD | Male-baised eQTL |
| rs7713979 | chr5:51418722:A:G | - | -0.0521232073158378 | 0.0429601602564629 | COAD | Male-baised eQTL |
| rs9291766 | chr5:51419420:G:A | - | -0.0521232073158378 | 0.0429601602564629 | COAD | Male-baised eQTL |
| rs6861333 | chr5:51408099:C:G | - | -0.0518956874147324 | 0.0438376746126364 | COAD | Male-baised eQTL |
| rs10939963 | chr5:51451668:A:C | - | -0.0517276190698261 | 0.0439666532682872 | COAD | Male-baised eQTL |
| rs11744196 | chr5:52616706:G:C | - | 0.049512929229355 | 0.0439835822304018 | COAD | Male-baised eQTL |
| rs7720200 | chr5:56355934:A:G | - | 0.0725034763828045 | 0.0457337830020709 | COAD | Male-baised eQTL |
| rs1494638 | chr5:64120801:C:T | - | 0.0686677150042376 | 0.0470086480651108 | COAD | Male-baised eQTL |
| rs1823428 | chr5:64137088:C:T | - | 0.0686677150042376 | 0.0470086480651108 | COAD | Male-baised eQTL |
| rs10939960 | chr5:51442613:C:T | - | -0.0517192446991084 | 0.047747438684493 | COAD | Male-baised eQTL |
| rs7709134 | chr5:51397342:G:A | - | -0.0503926908880759 | 0.0484295587557995 | COAD | Male-baised eQTL |
| rs10043658 | chr5:51437588:A:G | - | -0.0508474415426612 | 0.0493436712554947 | COAD | Male-baised eQTL |
| rs6891088 | chr5:51438580:T:C | - | -0.0508474415426612 | 0.0493436712554947 | COAD | Male-baised eQTL |
| rs10066521 | chr5:51425991:G:T | - | -0.0506527379106706 | 0.049673156162738 | COAD | Male-baised eQTL |
| rs62368261 | chr5:51426547:G:A | - | -0.0506527379106706 | 0.049673156162738 | COAD | Male-baised eQTL |
| rs10939954 | chr5:51428940:A:G | - | -0.0506527379106706 | 0.049673156162738 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000178996 |
| CpG Site: cg23001370 | |
| Position to Gene: gene,enhancer | |
| Male Effect: - | |
| Female Effect: -0.451571994319475 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg23001370 | chr5:54521243 | gene,enhancer | -0.451571994319475 | 1.04589111432055e-14 | -0.49270977910012975 | 5.309217644082893e-17 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of SNX18 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000178996 | SNX18 | C0019193 | Hepatitis, Toxic | 1 | CTD_human |
| ENSG00000178996 | SNX18 | C0860207 | Drug-Induced Liver Disease | 1 | CTD_human |
| ENSG00000178996 | SNX18 | C1262760 | Hepatitis, Drug-Induced | 1 | CTD_human |
| ENSG00000178996 | SNX18 | C3658290 | Drug-Induced Acute Liver Injury | 1 | CTD_human |
| ENSG00000178996 | SNX18 | C4277682 | Chemical and Drug Induced Liver Injury | 1 | CTD_human |
| ENSG00000178996 | SNX18 | C4279912 | Chemically-Induced Liver Toxicity | 1 | CTD_human |
