SexAnnoDB Logo

Home

Download

Statistics

Examples

Help

Contact

Center for Computational Systems Medicine
leaf

Gene summary

leaf

Gene structure and Gene expression level

leaf

Sex-biased somatic mutation

leaf

DNA methylation with beta values in gene

leaf

Exon skipping events with PSI in TCGA

leaf

RNA A-to-I editing events in TCGA

leaf

Sex-biased TF-Gene network of gene

leaf

Sex-biased RBP-ES network of gene

leaf

Sex-biased CeRNA regulation of gene

leaf

Sex-biased eQTL regulation of gene

leaf

Sex-biased eQTM regulation of gene

leaf

Sex-biased sQTL regulation of gene

leaf

Sex-biased sQTM regulation of gene

leaf

Related disease information of gene

Gene: ENSG00000177494

Summary for ZBED2

check button Gene summary

Gene informationEnsembl ID

ENSG00000177494

Gene symbol

ZBED2

Gene namezinc finger BED-type containing 2
HGNC

20710

Entrez ID

79413

Gene typeprotein_coding
SynonymsZBED2|MGC10796
UniProtAcc

Q9BTP6


check buttonDrugs associated with this gene(DrugBank).
Gene IDGene SymbolDrug IDDrug NameDrug Type

check buttonCancer therapeutic drugs associated with this gene(NCI).
Gene IDGene NameDrug IDDrug NameDrug TypeCancer

Top

Structure and expression level for ZBED2

check buttonAS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure.
∗For more information on exon skipping events please check the ExonskipDB database.
∗For more information on exon skipping events please check the CAeditome database.
UCSC result

check buttonLandscape of gene expressions across multiple cancer types.
gene expression analysis

check buttonDifferentially expressed gene analysis between tumor male and tumor female samples.
DEG result
Coding NameBase Meanlog2FoldChangelfcSEStatP valueP.adjust ValueCancer Type
ZBED21.17e+02-1.08e+003.11e-01-3.46e+005.31e-043.33e-03KIRP

check buttonDifferentially expressed gene analysis between tumor male and normal male samples.
DEG result
Coding NameBase Meanlog2FoldChangelfcSEStatP valueP.adjust ValueCancer Type
ZBED22.72e+024.29e+007.67e-015.60e+002.17e-082.58e-07BLCA
ZBED25.68e+023.43e+007.56e-014.54e+005.64e-069.92e-05ESCA

check buttonDifferentially expressed gene analysis between tumor female and normal female samples.
Coding NameBase Meanlog2FoldChangelfcSEStatP valueP.adjust ValueCancer Type

Top

Sex-biased somatic mutation for ZBED2

∗For more information on exon skipping events please check the ExonskipDB database.
Gene IDCancer TypeHugo SymbolMaleFemalepvalorci.upci.lowadjPval

Top

DNA methylation with beta values for ZBED2

check buttonLandscape of DNA methylation across multiple cancer types.
methylation heatmap

check buttonDifferentially expressed CpG sites between male tumor and female tumor patients.
Cancer TypeCpG SitePositionCpG IslandPosition to Geneave1ave2wilcoxon.wwilcoxon.ppadjdBeta
LIHCcg23670794chr3:111594218CGI:chr3:111674480-111674697UTR,promoter,exon,gene body6.44e-015.14e-014.42e+001.01e-051.10e-041.31e-01
LIHCcg25298754chr3:111595255CGI:chr3:111674480-111674697promoter,gene body6.09e-014.89e-014.46e+008.38e-069.40e-051.20e-01

check buttonDifferentially expressed CpG sites between male tumor and male normal patients.
Cancer TypeCpG SitePositionCpG IslandPosition to Geneave1ave2wilcoxon.wwilcoxon.ppadjdBeta
HNSCcg23670794chr3:111594218CGI:chr3:111674480-111674697UTR,promoter,exon,gene body3.62e-014.83e-01-2.33e+001.98e-022.29e-02-1.21e-01
HNSCcg25298754chr3:111595255CGI:chr3:111674480-111674697promoter,gene body2.90e-014.14e-01-2.62e+008.80e-031.15e-02-1.23e-01
LUSCcg23670794chr3:111594218CGI:chr3:111674480-111674697UTR,promoter,exon,gene body5.56e-017.55e-01-2.95e+003.19e-035.86e-03-1.99e-01
LUSCcg25298754chr3:111595255CGI:chr3:111674480-111674697promoter,gene body4.08e-015.25e-01-2.60e+009.45e-031.33e-02-1.17e-01
LUSCcg24323726chr3:111595339CGI:chr3:111674480-111674697UTR,promoter,exon,gene body4.29e-015.42e-01-2.89e+003.83e-036.69e-03-1.13e-01
COADcg24323726chr3:111595339CGI:chr3:111674480-111674697UTR,promoter,exon,gene body6.20e-017.32e-01-2.25e+002.44e-022.89e-02-1.12e-01
BLCAcg25298754chr3:111595255CGI:chr3:111674480-111674697promoter,gene body5.97e-018.41e-01-3.59e+003.36e-049.79e-04-2.44e-01
BLCAcg24323726chr3:111595339CGI:chr3:111674480-111674697UTR,promoter,exon,gene body6.10e-017.90e-01-3.09e+001.98e-033.89e-03-1.81e-01
ESCAcg24323726chr3:111595339CGI:chr3:111674480-111674697UTR,promoter,exon,gene body4.76e-016.59e-01-2.17e+002.97e-024.37e-02-1.83e-01

check buttonDifferentially expressed CpG sites between female tumor and female normal patients.
Cancer TypeCpG SitePositionCpG IslandPosition to Geneave1ave2wilcoxon.wwilcoxon.ppadjdBeta
BRCAcg23670794chr3:111594218CGI:chr3:111674480-111674697UTR,promoter,exon,gene body7.24e-019.09e-01-1.05e+017.58e-266.99e-25-1.85e-01
BRCAcg25298754chr3:111595255CGI:chr3:111674480-111674697promoter,gene body6.37e-017.67e-01-5.79e+006.84e-091.55e-08-1.30e-01

Top

Exon skipping events with PSI in TCGA for ZBED2

∗Please access ExonSkipDB for exon skipping annotation.
check buttonDifferentially expressed exon skipping events between male tumor and female tumor patients.
Cancer TypeExon Skippingave.female_Tave.female_Nwilcoxon.wwilcoxon.ppadjdPSI

check buttonDifferentially expressed exon skipping events between male tumor and male normal patients.
Cancer TypeExon Skippingave.female_Tave.female_Nwilcoxon.wwilcoxon.ppadjdPSI

check buttonDifferentially expressed exon skipping events between female tumor and female normal patients.
Cancer TypeExon Skippingave.female_Tave.female_Nwilcoxon.wwilcoxon.ppadjdPSI

Top

RNA A-to-I editing events in TCGA for ZBED2

∗Please access CAeditome for RNA editing annotation.
check buttonDifferentially expressed RNA editing events between male tumor and female tumor patients.
Cancer TypeTranscriptEditingave.male_Tave.female_Twilcoxon.wwilcoxon.pp_adjdFre

check buttonDifferentially expressed RNA editing events between male tumor and male normal patients.
Cancer TypeTranscriptEditingave.male_Tave.female_Twilcoxon.wwilcoxon.pp_adjdFre

check buttonDifferentially expressed RNA editing events between female tumor and female normal patients.
Cancer TypeTranscriptEditingave.male_Tave.female_Twilcoxon.wwilcoxon.pp_adjdFre

check buttonProtein coding RNA editing(s).
Editing PositionVariant TypeGene SymbolTranscript IDNTchangeAAchange

Top

Sex-biased TF-Gene network for ZBED2

check buttonTFs related to ZBED2.
∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98.
∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98.
TF Gene
Cancer TypeTFTarget GeneMale Edge ScoreMale Edge ThresholdFemale Edge ScoreFemale Edge ThresholdType
CHOLFOXR2ZBED24.94e+009.96e-013.52e+001.65e-03Male-biased
CHOLMSX1ZBED25.52e+009.91e-014.46e+007.48e-03Male-biased
CHOLMSX2ZBED25.44e+009.90e-014.43e+008.89e-03Male-biased
CHOLPOU3F3ZBED25.40e+009.94e-014.21e+004.42e-03Male-biased
CHOLPOU4F1ZBED25.47e+009.94e-014.28e+004.32e-03Male-biased
CHOLZNF713ZBED25.20e+009.83e-014.32e+001.46e-02Male-biased
CHOLZNF716ZBED25.08e+009.92e-013.95e+005.61e-03Male-biased
CHOLZNF79ZBED24.89e+009.96e-013.42e+001.32e-03Male-biased
DLBCARGFXZBED25.90e+009.96e-014.76e+003.53e-03Male-biased
DLBCFOXR2ZBED24.27e+009.90e-012.15e+001.29e-04Male-biased
DLBCISXZBED25.86e+009.96e-014.70e+003.21e-03Male-biased
DLBCMSX1ZBED25.37e+009.95e-014.16e+002.76e-03Male-biased
DLBCMSX2ZBED25.26e+009.96e-014.02e+002.39e-03Male-biased
DLBCPBX4ZBED25.94e+009.86e-015.15e+001.35e-02Male-biased
DLBCPOU3F3ZBED24.97e+009.96e-013.28e+005.15e-04Male-biased
DLBCPOU4F1ZBED25.18e+009.95e-014.02e+003.12e-03Male-biased
DLBCSNAI1ZBED23.07e+005.26e-034.13e+009.83e-01Female-biased
DLBCZNF677ZBED24.38e+009.90e-013.03e+001.55e-03Male-biased
DLBCZNF713ZBED25.10e+009.86e-014.26e+001.12e-02Male-biased
DLBCZNF716ZBED24.59e+009.93e-013.12e+001.01e-03Male-biased
DLBCZNF79ZBED24.19e+009.89e-011.94e+008.82e-05Male-biased
DLBCZSCAN23ZBED25.86e+009.84e-015.10e+001.50e-02Male-biased
ESCAARGFXZBED25.78e+009.88e-015.07e+001.05e-02Male-biased
ESCADLX3ZBED25.98e+009.86e-015.30e+001.30e-02Male-biased
ESCAFOXR2ZBED24.39e+009.90e-013.46e+003.05e-03Male-biased
ESCAISXZBED25.84e+009.92e-015.05e+006.73e-03Male-biased
ESCAMSX1ZBED25.26e+009.86e-014.57e+001.20e-02Male-biased
ESCAMSX2ZBED25.22e+009.89e-014.48e+008.74e-03Male-biased
ESCAPBX4ZBED25.71e+009.90e-014.97e+008.80e-03Male-biased
ESCAPOU3F3ZBED25.00e+009.92e-014.15e+004.91e-03Male-biased
ESCAPOU4F1ZBED25.28e+009.84e-014.62e+001.41e-02Male-biased
ESCAZNF33AZBED22.36e+006.65e-043.72e+009.82e-01Female-biased
MESOFOXR2ZBED24.32e+006.15e-035.76e+009.93e-01Female-biased
MESOPOU3F3ZBED24.69e+009.34e-036.00e+009.90e-01Female-biased
MESOZNF79ZBED24.29e+004.27e-035.84e+009.95e-01Female-biased
PCPGARGFXZBED25.44e+009.91e-014.54e+006.82e-03Male-biased
PCPGFOXR2ZBED23.96e+009.83e-012.56e+005.41e-04Male-biased
PCPGHSFY2ZBED25.40e+009.85e-014.66e+001.32e-02Male-biased
PCPGISXZBED25.44e+009.95e-014.39e+003.32e-03Male-biased
PCPGMSX1ZBED24.83e+009.92e-013.80e+003.67e-03Male-biased
PCPGMSX2ZBED24.82e+009.92e-013.77e+003.26e-03Male-biased
PCPGPBX4ZBED25.38e+009.90e-014.54e+008.57e-03Male-biased
PCPGPOU3F3ZBED24.59e+009.93e-013.28e+009.16e-04Male-biased
PCPGPOU4F1ZBED24.92e+009.94e-013.77e+002.06e-03Male-biased
PCPGSNAI1ZBED22.73e+006.24e-044.12e+009.88e-01Female-biased
PCPGZNF281ZBED22.30e+002.25e-043.90e+009.84e-01Female-biased
PCPGZNF341ZBED22.61e+001.35e-033.84e+009.81e-01Female-biased
PCPGZNF444ZBED22.37e+003.44e-043.88e+009.83e-01Female-biased
PCPGZNF468ZBED22.40e+002.94e-043.94e+009.85e-01Female-biased
PCPGZNF554ZBED22.75e+006.09e-044.15e+009.89e-01Female-biased
PCPGZNF713ZBED24.62e+009.84e-013.82e+001.02e-02Male-biased
PCPGZNF716ZBED24.22e+009.84e-013.27e+005.11e-03Male-biased
PCPGZNF740ZBED22.60e+004.97e-044.03e+009.87e-01Female-biased
PCPGZNF79ZBED23.85e+009.80e-012.50e+006.61e-04Male-biased
PCPGZSCAN30ZBED22.46e+001.95e-044.09e+009.88e-01Female-biased
SARCTOPORSZBED24.31e+009.80e-013.75e+009.86e-03Male-biased
SARCZNF121ZBED24.66e+009.93e-013.71e+001.06e-03Male-biased
SARCZNF181ZBED24.67e+009.93e-013.76e+001.38e-03Male-biased
SARCZNF235ZBED24.40e+009.89e-013.63e+002.87e-03Male-biased
SARCZNF287ZBED24.12e+009.83e-013.40e+003.71e-03Male-biased
SARCZNF33AZBED24.69e+009.94e-013.72e+009.62e-04Male-biased
SARCZNF443ZBED24.90e+009.95e-013.95e+001.05e-03Male-biased
SKCMARGFXZBED25.11e+001.15e-026.05e+009.87e-01Female-biased
SKCMFOXR2ZBED23.25e+002.07e-034.73e+009.88e-01Female-biased
SKCMISXZBED24.98e+001.13e-025.92e+009.87e-01Female-biased
SKCMMSX1ZBED24.46e+007.30e-035.54e+009.90e-01Female-biased
SKCMMSX2ZBED24.35e+006.87e-035.45e+009.90e-01Female-biased
SKCMPBX4ZBED25.05e+001.46e-025.91e+009.84e-01Female-biased
SKCMPOU3F3ZBED24.03e+004.15e-035.30e+009.92e-01Female-biased
SKCMPOU4F1ZBED24.38e+007.91e-035.44e+009.89e-01Female-biased
SKCMZNF716ZBED23.87e+007.29e-034.95e+009.85e-01Female-biased
SKCMZNF79ZBED23.19e+001.78e-034.71e+009.88e-01Female-biased

check buttonZBED2 related gene.
∗Only the gene encode TF might with this result.
∗For more information please check Sex-biased TF-Coding gene network.

Top

Sex-biased RBP-ES network for ZBED2

check buttonRBPs related to ES in ZBED2.
∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98.
∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98.
Cancer TypeRBPTarget ESMale Edge ScoreMale Edge ThresholdFemale Edge ScoreFemale Edge ThresholdType

check buttonZBED2 related ES.
∗Only the gene encode RBP might with this result.
∗For more information please check Sex-biased RBP-ES network in cancer.

Top

Sex-biased CeRNA regulation of gene

check buttonSex-biased CeRNA regulation of gene.
Gene IDceRNA(lncRNA-miRNA-mRNA)GroupCancer Type

Top

Sex-biased eQTL regulation of gene

check buttonSex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).
eQTLDescription

check buttonMale-specific eQTL regulation.
SNP IDSNP InfoPosition to GeneEffect ScoreFDRCancer TypeBiased Type
rs4682422chr3:112759877:A:G-0.1561277557601010.038434056209339LUSCFemale-baised eQTL
rs79029293chr3:118538421:T:C-0.2093033061658580.0182136399280129BLCAFemale-baised eQTL
rs80054479chr3:118618921:T:C-0.2127926058489670.0449613143558171BLCAFemale-baised eQTL

check buttonFemale-specific eQTL regulation.
SNP IDSNP InfoPosition to GeneEffect ScoreFDRCancer TypeBiased Type
rs61797775chr3:120257317:A:G-0.07329744808214550.00640035329097754LUSCMale-baised eQTL
rs28495065chr3:120258800:A:G-0.07045133225400510.0114331375570716LUSCMale-baised eQTL
rs9811713chr3:120248592:C:T-0.06797273638816110.0177693636737144LUSCMale-baised eQTL
rs6438275chr3:115611416:A:G--0.08104040267426230.048755315104507BLCAMale-baised eQTL
rs6764017chr3:110660988:C:T-0.1015665485001720.0326375711999925LUADMale-baised eQTL

check buttonOpposite sex-biased eQTL regulation.
SNP IDSNP InfoPosition to GeneMale EffectMale FDRFemale EffectFemale FDRSex-biased Gene in CancerCancer Type

Top

Sex-biased eQTM regulation of gene

check buttonSex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table).
eQTMDescription

check buttonMale-specific eQTM regulation.
CpG SiteCpG PostionPosition to GeneEffect ScoreFDRCor.rCor.PvalueCancer Type

check buttonFemale-specific eQTM regulation.
CpG SiteCpG PostionPosition to GeneEffect ScoreFDRCor.rCor.PvalueCancer Type

check buttonOpposite sex-biased eQTM regulation.
CpG SiteCpG PostionCpG IslandPosition to GeneMale EffectMale FDRFemale EffectFemale FDRMale CorMale P-valueFemale CorFemale P-valueSex-biased Coding GeneCancer Type

Top

Sex-biased sQTL regulation of gene

check buttonSex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).
sQTLDescription

check buttonMale-specific sQTL regulation.
ES IDSkipped ExonORF AnnoSNP IDSNP InfoSNP Position to ESEffect ScoreFDRCancer TypeBiased Type

check buttonFemale-specific sQTL regulation.
ES IDSkipped ExonORF AnnoSNP IDSNP InfoSNP Position to ESEffect ScoreFDRCancer TypeBiased Type

check buttonOpposite sex-biased sQTL regulation.
ES IDSkipped ExonORF AnnoSNP IDSNP InfoSNP Position to ESMale EffectMale FDRFemale EffectFemale FDRCancer Type

Top

Sex-biased sQTM regulation of gene

check buttonSex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table).
sQTMDescription

check buttonMale-specific sQTM regulation.
EX IDSkipped ExonCPG SiteCPG PositionPosition to EX EventsEffect ScoreFDRCor.rCor.PvalueORF_annoCancer Type

check buttonFemale-specific sQTM regulation.
EX IDSkipped ExonCPG SiteCPG PositionPosition to EX EventsEffect ScoreFDRCor.rCor.PvalueORF_annoCancer Type

check buttonOpposite sex-biased sQTM regulation.
EX IDEX InfoSkipped ExonCPG SiteCPG PositionCPG IslandPosition to EX EventsMale EffectMale FDRFemale EffectFemale FDRMale CorrelationMale P-valueFemale CorrelationFemale P-valueORF_annoCancer Type

Top

Related disease information of ZBED2

check buttonDiseases associated with this gene (DisGeNET).
Gene IDGene SymbolDisease IDDisease NameNumber of PMIDSource