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Gene: ENSG00000175711 |
Summary for B3GNTL1 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000175711 | Gene symbol | B3GNTL1 |
| Gene name | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1 | |
| HGNC | 21727 | |
| Entrez ID | 146712 | |
| Gene type | protein_coding | |
| Synonyms | B3GNTL1|B3GNT8 | |
| UniProtAcc | Q67FW5 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
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Structure and expression level for B3GNTL1 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
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| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| B3GNTL1 | 3.83e+02 | 1.04e+00 | 2.15e-01 | 4.82e+00 | 1.40e-06 | 1.05e-05 | BLCA |
| B3GNTL1 | 3.46e+02 | 1.45e+00 | 3.22e-01 | 4.50e+00 | 6.82e-06 | 4.00e-05 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
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| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| B3GNTL1 | 2.76e+02 | 1.94e+00 | 2.68e-01 | 7.22e+00 | 5.07e-13 | 2.51e-11 | READ |
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Sex-biased somatic mutation for B3GNTL1 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for B3GNTL1 |
| Landscape of DNA methylation across multiple cancer types. |
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| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUSC | cg05361728 | chr17:83052368 | CGI:chr17:83051075-83052123 | promoter | 6.68e-01 | 7.97e-01 | -3.50e+00 | 4.58e-04 | 1.57e-03 | -1.29e-01 |
| BLCA | cg05361728 | chr17:83052368 | CGI:chr17:83051075-83052123 | promoter | 6.57e-01 | 8.00e-01 | -3.80e+00 | 1.46e-04 | 5.25e-04 | -1.44e-01 |
| ESCA | cg22242345 | chr17:83053137 | CGI:chr17:83051075-83052123 | promoter | 8.61e-01 | 6.96e-01 | 3.06e+00 | 2.23e-03 | 3.37e-02 | 1.66e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
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Exon skipping events with PSI in TCGA for B3GNTL1 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
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| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
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RNA A-to-I editing events in TCGA for B3GNTL1 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for B3GNTL1 |
| TFs related to B3GNTL1. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| B3GNTL1 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for B3GNTL1 |
| RBPs related to ES in B3GNTL1. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| THYM | FXR2 | exon_skip_295243 | 7.60e+00 | 3.31e-03 | 8.02e+00 | 9.88e-01 | Female-biased |
| COAD | FMR1 | exon_skip_295249 | 8.69e+00 | 9.87e-01 | 8.33e+00 | 7.83e-03 | Male-biased |
| DLBC | PCBP1 | exon_skip_295243 | 7.75e+00 | 9.85e-01 | 7.35e+00 | 5.28e-03 | Male-biased |
| DLBC | ZFP36 | exon_skip_295254 | 9.22e+00 | 5.25e-03 | 9.61e+00 | 9.92e-01 | Female-biased |
| LUAD | FMR1 | exon_skip_295249 | 8.59e+00 | 9.87e-01 | 8.23e+00 | 6.95e-03 | Male-biased |
| MESO | FXR2 | exon_skip_295243 | 7.74e+00 | 1.01e-02 | 8.09e+00 | 9.81e-01 | Female-biased |
| B3GNTL1 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs9903350 | chr17:78186242:G:T | - | 0.139535783274344 | 0.0215772174759382 | BLCA | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs3935680 | chr17:75099733:T:C | - | -0.0638662453549839 | 0.00557589534142596 | BLCA | Male-baised eQTL |
| rs4789139 | chr17:75102130:A:G | - | -0.0622794402296027 | 0.0071460133131113 | BLCA | Male-baised eQTL |
| rs11077775 | chr17:75100971:C:G | - | -0.0615726889746723 | 0.00820391280335184 | BLCA | Male-baised eQTL |
| rs11652195 | chr17:75101454:T:C | - | -0.0615726889746723 | 0.00820391280335184 | BLCA | Male-baised eQTL |
| rs4238978 | chr17:75100856:A:G | - | 0.0610593432080154 | 0.00882804722168828 | BLCA | Male-baised eQTL |
| rs868203 | chr17:82800322:C:T | - | 0.13866641291463 | 0.00340994868732902 | COAD | Male-baised eQTL |
| rs56697906 | chr17:82782365:C:T | - | 0.147311305189961 | 0.0064296697373932 | COAD | Male-baised eQTL |
| rs7212130 | chr17:82790388:C:G | - | 0.128722185894955 | 0.00845746858618354 | COAD | Male-baised eQTL |
| rs7224961 | chr17:82790578:T:C | - | 0.128722185894955 | 0.00845746858618354 | COAD | Male-baised eQTL |
| rs112689241 | chr17:82801692:C:T | - | 0.121689577769168 | 0.014871010292019 | COAD | Male-baised eQTL |
| rs2620004 | chr17:73714952:T:C | - | 0.0562126535571211 | 0.0328697979044967 | COAD | Male-baised eQTL |
| rs9911105 | chr17:76376057:G:T | - | 0.119052107507506 | 0.0476842888020887 | COAD | Male-baised eQTL |
| rs9912914 | chr17:76376069:C:G | - | 0.119052107507506 | 0.0476842888020887 | COAD | Male-baised eQTL |
| rs9893040 | chr17:76376478:T:A | - | 0.119052107507506 | 0.0476842888020887 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000175711 |
| CpG Site: cg05784951 | |
| Position to Gene: gene | |
| Male Effect: -0.408394638079405 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg05784951 | chr17:83010286 | gene | -0.408394638079405 | 2.54018835698091e-09 | -0.4446500032677896 | 3.177313096543373e-12 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of B3GNTL1 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
