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Gene: ENSG00000172594 |
Summary for SMPDL3A |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000172594 | Gene symbol | SMPDL3A |
| Gene name | sphingomyelin phosphodiesterase acid like 3A | |
| HGNC | 17389 | |
| Entrez ID | 10924 | |
| Gene type | protein_coding | |
| Synonyms | SMPDL3A|FLJ20177|ASM3A|ASML3a|yR36GH4.1 | |
| UniProtAcc | Q92484 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for SMPDL3A |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| SMPDL3A | 1.61e+03 | -1.28e+00 | 2.12e-01 | -6.05e+00 | 1.45e-09 | 1.61e-08 | STAD |
| SMPDL3A | 1.15e+03 | -2.28e+00 | 4.73e-01 | -4.83e+00 | 1.39e-06 | 9.67e-06 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| SMPDL3A | 5.22e+02 | -1.02e+00 | 3.50e-01 | -2.90e+00 | 3.72e-03 | 2.27e-02 | BLCA |
| SMPDL3A | 8.79e+02 | -2.50e+00 | 3.18e-01 | -7.86e+00 | 3.85e-15 | 3.25e-13 | READ |
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Sex-biased somatic mutation for SMPDL3A |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for SMPDL3A |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| THCA | cg19409187 | chr6:122788758 | CGI:chr6:122789143-122789733 | promoter | 4.95e-01 | 6.30e-01 | -3.27e+00 | 1.09e-03 | 3.33e-03 | -1.35e-01 |
| HNSC | cg02104893 | chr6:122788246 | CGI:chr6:122789143-122789733 | promoter | 6.49e-01 | 7.70e-01 | -2.78e+00 | 5.41e-03 | 7.61e-03 | -1.22e-01 |
| LUSC | cg01050920 | chr6:122788596 | CGI:chr6:122789143-122789733 | promoter | 4.31e-01 | 5.92e-01 | -2.91e+00 | 3.60e-03 | 6.40e-03 | -1.61e-01 |
| COAD | cg01050920 | chr6:122788596 | CGI:chr6:122789143-122789733 | promoter | 3.72e-01 | 5.44e-01 | -4.15e+00 | 3.37e-05 | 1.49e-04 | -1.72e-01 |
| BLCA | cg01050920 | chr6:122788596 | CGI:chr6:122789143-122789733 | promoter | 3.14e-01 | 4.59e-01 | -3.09e+00 | 2.00e-03 | 3.92e-03 | -1.45e-01 |
| LIHC | cg01050920 | chr6:122788596 | CGI:chr6:122789143-122789733 | promoter | 3.99e-01 | 5.41e-01 | -3.96e+00 | 7.48e-05 | 1.60e-04 | -1.42e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg12379307 | chr6:122788692 | CGI:chr6:122789143-122789733 | promoter | 4.73e-01 | 5.83e-01 | -2.47e+00 | 1.33e-02 | 2.06e-02 | -1.10e-01 |
| HNSC | cg19409187 | chr6:122788758 | CGI:chr6:122789143-122789733 | promoter | 3.53e-01 | 2.19e-01 | 2.53e+00 | 1.13e-02 | 1.99e-02 | 1.34e-01 |
| COAD | cg02104893 | chr6:122788246 | CGI:chr6:122789143-122789733 | promoter | 7.74e-01 | 8.85e-01 | -2.77e+00 | 5.54e-03 | 1.02e-02 | -1.10e-01 |
| BLCA | cg19409187 | chr6:122788758 | CGI:chr6:122789143-122789733 | promoter | 2.33e-01 | 3.36e-01 | -2.61e+00 | 8.96e-03 | 1.63e-02 | -1.03e-01 |
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Exon skipping events with PSI in TCGA for SMPDL3A |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| BRCA | exon_skip_454011 | 8.87e-01 | 7.85e-01 | 8.39e+00 | 4.85e-17 | 8.29e-16 | 1.02e-01 |
| KIRC | exon_skip_454006 | 6.71e-01 | 5.55e-01 | 3.97e+00 | 7.29e-05 | 5.29e-04 | 1.16e-01 |
| KICH | exon_skip_454011 | 6.65e-01 | 7.84e-01 | -2.21e+00 | 2.74e-02 | 3.60e-02 | -1.19e-01 |
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RNA A-to-I editing events in TCGA for SMPDL3A |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for SMPDL3A |
| TFs related to SMPDL3A. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| BLCA | FOXF2 | SMPDL3A | 5.89e+00 | 9.80e-01 | 5.25e+00 | 1.88e-02 | Male-biased |
| BLCA | FOXP2 | SMPDL3A | 5.08e+00 | 9.83e-01 | 4.37e+00 | 1.45e-02 | Male-biased |
| BLCA | NKX3-1 | SMPDL3A | 5.66e+00 | 9.93e-01 | 4.71e+00 | 6.18e-03 | Male-biased |
| BLCA | XPA | SMPDL3A | 3.89e+00 | 9.35e-03 | 4.76e+00 | 9.86e-01 | Female-biased |
| BLCA | YY2 | SMPDL3A | 4.90e+00 | 9.88e-01 | 4.05e+00 | 8.38e-03 | Male-biased |
| BLCA | ZBTB42 | SMPDL3A | 4.06e+00 | 9.44e-03 | 4.93e+00 | 9.87e-01 | Female-biased |
| BLCA | ZIM2 | SMPDL3A | 2.99e+00 | 2.01e-03 | 4.24e+00 | 9.87e-01 | Female-biased |
| BLCA | ZNF223 | SMPDL3A | 3.73e+00 | 7.19e-03 | 4.66e+00 | 9.87e-01 | Female-biased |
| BLCA | ZNF33B | SMPDL3A | 5.38e+00 | 9.87e-01 | 4.61e+00 | 1.15e-02 | Male-biased |
| BLCA | ZNF35 | SMPDL3A | 5.20e+00 | 9.93e-01 | 4.14e+00 | 4.25e-03 | Male-biased |
| BLCA | ZNF37A | SMPDL3A | 3.44e+00 | 2.12e-03 | 4.68e+00 | 9.92e-01 | Female-biased |
| BLCA | ZNF398 | SMPDL3A | 3.35e+00 | 6.06e-03 | 4.32e+00 | 9.84e-01 | Female-biased |
| BLCA | ZNF41 | SMPDL3A | 3.85e+00 | 1.34e-02 | 4.63e+00 | 9.80e-01 | Female-biased |
| BLCA | ZNF527 | SMPDL3A | 3.42e+00 | 8.27e-03 | 4.32e+00 | 9.81e-01 | Female-biased |
| BLCA | ZNF596 | SMPDL3A | 3.30e+00 | 4.77e-03 | 4.33e+00 | 9.85e-01 | Female-biased |
| BLCA | ZNF765 | SMPDL3A | 2.99e+00 | 1.65e-03 | 4.29e+00 | 9.88e-01 | Female-biased |
| BLCA | ZNF768 | SMPDL3A | 3.13e+00 | 4.38e-03 | 4.18e+00 | 9.83e-01 | Female-biased |
| CHOL | FOXP2 | SMPDL3A | 4.51e+00 | 1.72e-02 | 5.31e+00 | 9.81e-01 | Female-biased |
| CHOL | ZNF3 | SMPDL3A | 4.12e+00 | 1.54e-02 | 4.95e+00 | 9.82e-01 | Female-biased |
| CHOL | ZNF33B | SMPDL3A | 4.47e+00 | 5.20e-03 | 5.58e+00 | 9.93e-01 | Female-biased |
| CHOL | ZNF35 | SMPDL3A | 4.58e+00 | 1.44e-02 | 5.42e+00 | 9.84e-01 | Female-biased |
| LAML | FOXF2 | SMPDL3A | 4.80e+00 | 3.83e-03 | 5.96e+00 | 9.95e-01 | Female-biased |
| LAML | FOXK2 | SMPDL3A | 4.47e+00 | 3.86e-03 | 5.63e+00 | 9.95e-01 | Female-biased |
| LAML | FOXP2 | SMPDL3A | 3.89e+00 | 1.20e-03 | 5.34e+00 | 9.96e-01 | Female-biased |
| LAML | ISX | SMPDL3A | 4.87e+00 | 2.90e-03 | 6.10e+00 | 9.96e-01 | Female-biased |
| LAML | NKX3-1 | SMPDL3A | 4.16e+00 | 1.10e-03 | 5.63e+00 | 9.97e-01 | Female-biased |
| LAML | POU2F1 | SMPDL3A | 4.19e+00 | 1.70e-03 | 5.55e+00 | 9.97e-01 | Female-biased |
| LAML | PRRX1 | SMPDL3A | 5.05e+00 | 2.35e-03 | 6.34e+00 | 9.97e-01 | Female-biased |
| LAML | SPIC | SMPDL3A | 4.19e+00 | 5.66e-03 | 5.24e+00 | 9.92e-01 | Female-biased |
| LAML | TBX19 | SMPDL3A | 6.03e+00 | 1.23e-02 | 6.88e+00 | 9.87e-01 | Female-biased |
| LAML | ZNF3 | SMPDL3A | 3.80e+00 | 3.60e-03 | 4.97e+00 | 9.92e-01 | Female-biased |
| LAML | ZNF33B | SMPDL3A | 3.96e+00 | 1.47e-03 | 5.36e+00 | 9.96e-01 | Female-biased |
| LAML | ZNF35 | SMPDL3A | 3.65e+00 | 9.01e-04 | 5.16e+00 | 9.96e-01 | Female-biased |
| READ | FIGLA | SMPDL3A | 4.89e+00 | 9.81e-01 | 4.17e+00 | 1.50e-02 | Male-biased |
| READ | FOXP2 | SMPDL3A | 4.42e+00 | 5.28e-03 | 5.42e+00 | 9.93e-01 | Female-biased |
| READ | ISX | SMPDL3A | 5.48e+00 | 1.32e-02 | 6.24e+00 | 9.86e-01 | Female-biased |
| READ | MTF1 | SMPDL3A | 6.01e+00 | 9.90e-01 | 5.17e+00 | 9.23e-03 | Male-biased |
| READ | NKX3-1 | SMPDL3A | 4.76e+00 | 2.35e-03 | 5.99e+00 | 9.97e-01 | Female-biased |
| READ | POU2F1 | SMPDL3A | 4.78e+00 | 9.88e-03 | 5.61e+00 | 9.89e-01 | Female-biased |
| READ | SPIC | SMPDL3A | 4.13e+00 | 8.05e-03 | 5.02e+00 | 9.89e-01 | Female-biased |
| READ | XPA | SMPDL3A | 4.65e+00 | 9.91e-01 | 3.51e+00 | 2.81e-03 | Male-biased |
| READ | YY2 | SMPDL3A | 3.74e+00 | 2.16e-03 | 4.98e+00 | 9.95e-01 | Female-biased |
| READ | ZBTB42 | SMPDL3A | 5.01e+00 | 9.94e-01 | 3.85e+00 | 2.66e-03 | Male-biased |
| READ | ZNF223 | SMPDL3A | 4.64e+00 | 9.91e-01 | 3.46e+00 | 2.43e-03 | Male-biased |
| READ | ZNF3 | SMPDL3A | 4.22e+00 | 9.22e-03 | 5.07e+00 | 9.88e-01 | Female-biased |
| READ | ZNF33B | SMPDL3A | 4.38e+00 | 2.12e-03 | 5.64e+00 | 9.97e-01 | Female-biased |
| READ | ZNF35 | SMPDL3A | 4.07e+00 | 8.05e-04 | 5.61e+00 | 9.98e-01 | Female-biased |
| READ | ZNF597 | SMPDL3A | 3.89e+00 | 4.28e-03 | 4.95e+00 | 9.92e-01 | Female-biased |
| THYM | FOXF2 | SMPDL3A | 4.93e+00 | 5.09e-03 | 5.79e+00 | 9.94e-01 | Female-biased |
| THYM | FOXK2 | SMPDL3A | 4.76e+00 | 9.11e-03 | 5.48e+00 | 9.89e-01 | Female-biased |
| THYM | FOXP2 | SMPDL3A | 4.25e+00 | 3.06e-03 | 5.24e+00 | 9.94e-01 | Female-biased |
| THYM | ISX | SMPDL3A | 5.16e+00 | 3.94e-03 | 6.09e+00 | 9.95e-01 | Female-biased |
| THYM | NKX3-1 | SMPDL3A | 4.59e+00 | 1.10e-03 | 5.84e+00 | 9.98e-01 | Female-biased |
| THYM | POU2F1 | SMPDL3A | 4.51e+00 | 6.69e-03 | 5.30e+00 | 9.91e-01 | Female-biased |
| THYM | PRRX1 | SMPDL3A | 5.28e+00 | 4.51e-03 | 6.17e+00 | 9.95e-01 | Female-biased |
| THYM | SPIC | SMPDL3A | 4.18e+00 | 1.10e-02 | 4.84e+00 | 9.84e-01 | Female-biased |
| THYM | YY2 | SMPDL3A | 4.36e+00 | 1.25e-02 | 5.00e+00 | 9.84e-01 | Female-biased |
| THYM | ZNF182 | SMPDL3A | 3.09e+00 | 3.62e-03 | 4.02e+00 | 9.80e-01 | Female-biased |
| THYM | ZNF3 | SMPDL3A | 4.02e+00 | 6.17e-03 | 4.83e+00 | 9.89e-01 | Female-biased |
| THYM | ZNF33B | SMPDL3A | 4.48e+00 | 2.02e-03 | 5.58e+00 | 9.96e-01 | Female-biased |
| THYM | ZNF35 | SMPDL3A | 4.18e+00 | 6.91e-04 | 5.55e+00 | 9.98e-01 | Female-biased |
| SMPDL3A related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for SMPDL3A |
| RBPs related to ES in SMPDL3A. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| SMPDL3A related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs9488023 | chr6:112880572:C:T | - | 0.254336537724973 | 0.000192722147322378 | KIRP | Female-baised eQTL |
| rs7746739 | chr6:123707144:A:G | - | 0.221306443368512 | 0.000254955262011372 | KIRP | Female-baised eQTL |
| rs12661473 | chr6:123705959:A:G | - | 0.221536467574724 | 0.000258748722296734 | KIRP | Female-baised eQTL |
| rs1841244 | chr6:123706423:C:G | - | 0.212769691259899 | 0.000490268292727442 | KIRP | Female-baised eQTL |
| rs113531824 | chr6:114988038:A:G | - | 0.233091061884971 | 0.000545171943945632 | KIRP | Female-baised eQTL |
| rs371215857 | chr6:114975903:G:A | - | 0.22711052448152 | 0.000578099928440714 | KIRP | Female-baised eQTL |
| rs36132358 | chr6:114975025:T:A | - | 0.231231178328277 | 0.000620189387650501 | KIRP | Female-baised eQTL |
| rs34719095 | chr6:114976662:T:A | - | 0.231231178328277 | 0.000620189387650501 | KIRP | Female-baised eQTL |
| rs111434725 | chr6:114981963:G:A | - | 0.231231178328277 | 0.000620189387650501 | KIRP | Female-baised eQTL |
| rs17164510 | chr6:114986755:A:G | - | 0.231231178328277 | 0.000620189387650501 | KIRP | Female-baised eQTL |
| rs6942211 | chr6:126062319:G:A | - | 0.191479314998726 | 0.000827290249555388 | KIRP | Female-baised eQTL |
| rs7742867 | chr6:126063211:A:G | - | 0.191479314998726 | 0.000827290249555388 | KIRP | Female-baised eQTL |
| rs6906966 | chr6:126064835:T:C | - | 0.186034422049786 | 0.00127882011449565 | KIRP | Female-baised eQTL |
| rs6902444 | chr6:123675726:C:T | - | 0.194045745884337 | 0.00140669471666779 | KIRP | Female-baised eQTL |
| rs4289676 | chr6:123678158:G:A | - | 0.194045745884337 | 0.00140669471666779 | KIRP | Female-baised eQTL |
| rs2317885 | chr6:123678272:G:T | - | 0.194045745884337 | 0.00140669471666779 | KIRP | Female-baised eQTL |
| rs11961916 | chr6:123680720:G:A | - | 0.194045745884337 | 0.00140669471666779 | KIRP | Female-baised eQTL |
| rs77825619 | chr6:120132890:C:A | - | 0.224345553328936 | 0.00143428498028835 | KIRP | Female-baised eQTL |
| rs9490866 | chr6:123681420:T:C | - | 0.193866758652395 | 0.00150304390724712 | KIRP | Female-baised eQTL |
| rs7774699 | chr6:123682338:G:A | - | 0.193866758652395 | 0.00150304390724712 | KIRP | Female-baised eQTL |
| rs73773215 | chr6:123671587:A:G | - | 0.192345011025248 | 0.00190056047646535 | KIRP | Female-baised eQTL |
| rs6912369 | chr6:126065567:T:C | - | 0.185325698203379 | 0.00195237618391618 | KIRP | Female-baised eQTL |
| rs1026641 | chr6:113803286:A:G | - | 0.31136228661855 | 0.00321675002771518 | KIRP | Female-baised eQTL |
| rs756229 | chr6:114979210:G:T | - | 0.205545968753847 | 0.00637103705831536 | KIRP | Female-baised eQTL |
| rs1389639 | chr6:125467305:T:G | - | -0.174728731430169 | 0.00692788718694154 | KIRP | Female-baised eQTL |
| rs9488474 | chr6:114786743:A:T | - | 0.196880730339085 | 0.0074035414901104 | KIRP | Female-baised eQTL |
| rs9482426 | chr6:123687774:A:G | - | 0.173182038667858 | 0.00794205840098799 | KIRP | Female-baised eQTL |
| rs17053722 | chr6:125964187:A:G | - | 0.173095192989551 | 0.00811335007251969 | KIRP | Female-baised eQTL |
| rs6914536 | chr6:120082797:T:C | - | 0.194540574436512 | 0.0137112697558425 | KIRP | Female-baised eQTL |
| rs4896941 | chr6:125437442:C:T | - | -0.273428561075173 | 0.0154005609464497 | KIRP | Female-baised eQTL |
| rs1494140 | chr6:125438106:A:G | - | -0.273428561075173 | 0.0154005609464497 | KIRP | Female-baised eQTL |
| rs6931225 | chr6:125960113:C:T | - | 0.169920303819455 | 0.0191102760360515 | KIRP | Female-baised eQTL |
| rs17075063 | chr6:113367735:A:C | - | 0.19387601445168 | 0.0199463318418847 | KIRP | Female-baised eQTL |
| rs9490884 | chr6:123707845:C:A | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs9490885 | chr6:123709606:G:T | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs1841243 | chr6:123710124:G:C | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs7768112 | chr6:123710819:G:T | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs1817300 | chr6:123710897:G:A | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs1350640 | chr6:123710979:G:A | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs7768153 | chr6:123710986:C:T | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs1817299 | chr6:123711020:G:A | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs9490886 | chr6:123711739:T:C | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs12332863 | chr6:123711952:C:T | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs12332866 | chr6:123712105:G:A | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs1953170 | chr6:123712394:C:T | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs1953169 | chr6:123712398:C:T | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs4605910 | chr6:123712512:A:T | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs1953167 | chr6:123712702:T:C | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs9490887 | chr6:123713966:C:T | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs7772883 | chr6:123717331:G:A | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs7738719 | chr6:123717583:G:T | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs11154184 | chr6:123718474:A:T | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs2125766 | chr6:123720032:A:G | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs2125765 | chr6:123720264:C:T | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs2169091 | chr6:123720328:C:T | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs1020816 | chr6:123720475:C:G | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs6917714 | chr6:123720491:C:T | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs11154185 | chr6:123721092:C:T | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs11154186 | chr6:123721199:A:G | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs11154187 | chr6:123721428:C:A | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs9490889 | chr6:123721609:C:T | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs9320954 | chr6:123722081:A:G | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs9320955 | chr6:123722090:C:T | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs9320956 | chr6:123722101:A:T | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs6931527 | chr6:123723335:C:T | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs6931531 | chr6:123723342:C:T | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs6931576 | chr6:123723418:C:T | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs9482433 | chr6:123723705:A:G | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs9482435 | chr6:123723881:A:G | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs7341363 | chr6:123724246:G:A | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs17085743 | chr6:123724633:C:A | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs10440876 | chr6:123725992:C:A | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs112496488 | chr6:123726265:G:T | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs113918420 | chr6:123726361:T:C | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs114201377 | chr6:123726427:C:A | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs116410285 | chr6:123726456:G:A | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs112540928 | chr6:123726736:G:T | - | 0.165403098813478 | 0.0235145076422467 | KIRP | Female-baised eQTL |
| rs79945172 | chr6:131961674:G:A | - | 0.274318126764466 | 0.0237059785447611 | KIRP | Female-baised eQTL |
| rs7754672 | chr6:123717349:T:C | - | 0.165084665707169 | 0.0245670742630844 | KIRP | Female-baised eQTL |
| rs903277 | chr6:125445750:C:A | - | -0.139187256999154 | 0.0255289076315223 | KIRP | Female-baised eQTL |
| rs555335 | chr6:123736418:C:G | - | -0.145296900400388 | 0.0271598971037401 | KIRP | Female-baised eQTL |
| rs7756024 | chr6:125958042:G:T | - | 0.168889482444165 | 0.0273731607495379 | KIRP | Female-baised eQTL |
| rs7757099 | chr6:125449571:G:T | - | -0.161775863715328 | 0.0274451736330349 | KIRP | Female-baised eQTL |
| rs261759 | chr6:120190068:G:A | - | 0.182488019556769 | 0.0277109914533941 | KIRP | Female-baised eQTL |
| rs9490891 | chr6:123724450:A:G | - | 0.163547485167283 | 0.0285286041191474 | KIRP | Female-baised eQTL |
| rs9490892 | chr6:123724460:A:G | - | 0.163547485167283 | 0.0285286041191474 | KIRP | Female-baised eQTL |
| rs73592123 | chr6:126001622:T:A | - | 0.179833993489384 | 0.0323439953678464 | KIRP | Female-baised eQTL |
| rs1481434 | chr6:113636775:A:T | - | -0.23925211037931 | 0.0347771948061147 | KIRP | Female-baised eQTL |
| rs9372368 | chr6:113637180:A:G | - | -0.23925211037931 | 0.0347771948061147 | KIRP | Female-baised eQTL |
| rs73602322 | chr6:130105492:C:G | - | 0.274302256432594 | 0.0349970658587728 | KIRP | Female-baised eQTL |
| rs1572292 | chr6:130107079:G:A | - | 0.274302256432594 | 0.0349970658587728 | KIRP | Female-baised eQTL |
| rs12333165 | chr6:123711999:A:G | - | 0.162649858692159 | 0.0383555969689355 | KIRP | Female-baised eQTL |
| rs73773992 | chr6:128031274:G:A | - | 0.162997115189585 | 0.0387747372620662 | KIRP | Female-baised eQTL |
| rs17053745 | chr6:126025489:A:G | - | 0.14048382568109 | 0.0396355107373247 | KIRP | Female-baised eQTL |
| rs7769650 | chr6:126030486:G:A | - | 0.14048382568109 | 0.0396355107373247 | KIRP | Female-baised eQTL |
| rs2201362 | chr6:125457902:C:T | - | -0.170774444925239 | 0.0403976392715051 | KIRP | Female-baised eQTL |
| rs4945972 | chr6:113766544:A:G | - | -0.270153744514404 | 0.0419756621284362 | KIRP | Female-baised eQTL |
| rs9492951 | chr6:131392272:A:G | - | 0.140793731141803 | 0.0438448813248208 | KIRP | Female-baised eQTL |
| rs1494158 | chr6:125464011:T:C | - | -0.146179351695313 | 0.0446030971727007 | KIRP | Female-baised eQTL |
| rs1494157 | chr6:125464065:G:A | - | -0.146179351695313 | 0.0446030971727007 | KIRP | Female-baised eQTL |
| rs1494156 | chr6:125464155:C:G | - | -0.146179351695313 | 0.0446030971727007 | KIRP | Female-baised eQTL |
| rs4895736 | chr6:125464484:C:T | - | -0.146179351695313 | 0.0446030971727007 | KIRP | Female-baised eQTL |
| rs1826624 | chr6:125464587:G:A | - | -0.146179351695313 | 0.0446030971727007 | KIRP | Female-baised eQTL |
| rs114981261 | chr6:125465295:T:G | - | -0.146179351695313 | 0.0446030971727007 | KIRP | Female-baised eQTL |
| rs9375396 | chr6:125465468:T:C | - | -0.146179351695313 | 0.0446030971727007 | KIRP | Female-baised eQTL |
| rs9375397 | chr6:125465521:A:G | - | -0.146179351695313 | 0.0446030971727007 | KIRP | Female-baised eQTL |
| rs1908262 | chr6:125465572:G:A | - | -0.146179351695313 | 0.0446030971727007 | KIRP | Female-baised eQTL |
| rs1845411 | chr6:125467690:C:T | - | -0.146179351695313 | 0.0446030971727007 | KIRP | Female-baised eQTL |
| rs1845410 | chr6:125467744:C:G | - | -0.146179351695313 | 0.0446030971727007 | KIRP | Female-baised eQTL |
| rs183719294 | chr6:130117161:C:T | - | 0.244097777236326 | 0.045631670497255 | KIRP | Female-baised eQTL |
| rs9401746 | chr6:124443485:A:G | - | -0.105908832623768 | 0.00743066384153743 | LUSC | Female-baised eQTL |
| rs9491181 | chr6:124446676:A:G | - | -0.105908832623768 | 0.00743066384153743 | LUSC | Female-baised eQTL |
| rs6569385 | chr6:124448357:A:T | - | -0.105908832623768 | 0.00743066384153743 | LUSC | Female-baised eQTL |
| rs492962 | chr6:124451180:G:C | - | 0.105752002069831 | 0.00744338571034989 | LUSC | Female-baised eQTL |
| rs13220355 | chr6:124454116:G:T | - | 0.105752002069831 | 0.00744338571034989 | LUSC | Female-baised eQTL |
| rs2552085 | chr6:124454158:C:T | - | 0.105752002069831 | 0.00744338571034989 | LUSC | Female-baised eQTL |
| rs536032 | chr6:124455747:G:A | - | 0.105752002069831 | 0.00744338571034989 | LUSC | Female-baised eQTL |
| rs524235 | chr6:124450020:C:T | - | 0.105778212948305 | 0.0074966469305364 | LUSC | Female-baised eQTL |
| rs642608 | chr6:124450222:C:A | - | 0.104149867953198 | 0.00798858259852484 | LUSC | Female-baised eQTL |
| rs9374612 | chr6:116550927:C:T | - | 0.0327516792666716 | 0.0333288750859433 | LUAD | Female-baised eQTL |
| rs1570067 | chr6:116554976:G:A | - | 0.0327516792666716 | 0.0333288750859433 | LUAD | Female-baised eQTL |
| rs12528535 | chr6:116556471:C:T | - | 0.0327516792666716 | 0.0333288750859433 | LUAD | Female-baised eQTL |
| rs13203768 | chr6:116556643:C:T | - | 0.0327516792666716 | 0.0333288750859433 | LUAD | Female-baised eQTL |
| rs4245487 | chr6:116559676:C:A | - | 0.0327516792666716 | 0.0333288750859433 | LUAD | Female-baised eQTL |
| rs6921845 | chr6:116539150:T:G | - | 0.0327303225910332 | 0.0352111656359638 | LUAD | Female-baised eQTL |
| rs9400931 | chr6:116539620:T:C | - | 0.0327303225910332 | 0.0352111656359638 | LUAD | Female-baised eQTL |
| rs784129 | chr6:116624078:G:A | - | -0.0342292951670659 | 0.0354001158417908 | LUAD | Female-baised eQTL |
| rs1033722 | chr6:116561222:G:A | - | 0.0325250004396184 | 0.036606577770569 | LUAD | Female-baised eQTL |
| rs911195 | chr6:116566140:G:A | - | 0.0323690414247985 | 0.0383362072505363 | LUAD | Female-baised eQTL |
| rs2145336 | chr6:116537293:G:C | - | 0.0321573627760632 | 0.0400174864547237 | LUAD | Female-baised eQTL |
| rs10457308 | chr6:116591674:C:T | - | 0.0329831488584429 | 0.0464906634001678 | LUAD | Female-baised eQTL |
| rs9320565 | chr6:116514106:T:A | - | 0.0314913227431537 | 0.0468070992880272 | LUAD | Female-baised eQTL |
| rs9398439 | chr6:116514328:G:A | - | 0.0314913227431537 | 0.0468070992880272 | LUAD | Female-baised eQTL |
| rs9384982 | chr6:116514335:C:G | - | 0.0314913227431537 | 0.0468070992880272 | LUAD | Female-baised eQTL |
| rs881863 | chr6:116515557:G:A | - | 0.0314913227431537 | 0.0468070992880272 | LUAD | Female-baised eQTL |
| rs3734309 | chr6:116516147:G:A | - | 0.0314913227431537 | 0.0468070992880272 | LUAD | Female-baised eQTL |
| rs2281590 | chr6:116519416:C:T | - | 0.0313653049786586 | 0.0484632424571548 | LUAD | Female-baised eQTL |
| rs2145335 | chr6:116528376:C:T | - | 0.0312699921682367 | 0.048851832039988 | LUAD | Female-baised eQTL |
| rs1321532 | chr6:116529809:C:G | - | 0.0312699921682367 | 0.048851832039988 | LUAD | Female-baised eQTL |
| rs17061077 | chr6:132218244:A:G | - | 0.15890083697932 | 1.83865188487426e-05 | COAD | Female-baised eQTL |
| rs9493241 | chr6:132217993:C:T | - | 0.135503751729824 | 0.000539604956366754 | COAD | Female-baised eQTL |
| rs7752804 | chr6:120257425:C:T | - | 0.0700618641885711 | 0.0218860562254233 | COAD | Female-baised eQTL |
| rs9387727 | chr6:120264165:T:C | - | 0.0700618641885711 | 0.0218860562254233 | COAD | Female-baised eQTL |
| rs9387728 | chr6:120264167:T:G | - | 0.0700618641885711 | 0.0218860562254233 | COAD | Female-baised eQTL |
| rs12527744 | chr6:130874497:T:A | - | 0.0631465378006844 | 0.0258854641478145 | COAD | Female-baised eQTL |
| rs12529323 | chr6:130874498:A:G | - | 0.0631465378006844 | 0.0258854641478145 | COAD | Female-baised eQTL |
| rs11754472 | chr6:130859494:G:C | - | 0.0637596225554 | 0.0258864208287049 | COAD | Female-baised eQTL |
| rs3777434 | chr6:130867172:T:C | - | 0.0634239904400507 | 0.0260504665547359 | COAD | Female-baised eQTL |
| rs6569707 | chr6:130858661:G:C | - | 0.0632044155817368 | 0.0265374736896859 | COAD | Female-baised eQTL |
| rs9388863 | chr6:130865001:T:G | - | 0.0629407542470628 | 0.0266815736307246 | COAD | Female-baised eQTL |
| rs7775013 | chr6:130865438:T:G | - | 0.0629407542470628 | 0.0266815736307246 | COAD | Female-baised eQTL |
| rs3777436 | chr6:130868394:T:G | - | 0.0629407542470628 | 0.0266815736307246 | COAD | Female-baised eQTL |
| rs7739379 | chr6:130861138:T:C | - | 0.06331093644363 | 0.0274188902875786 | COAD | Female-baised eQTL |
| rs6569708 | chr6:130858792:G:T | - | 0.0627811237418026 | 0.029417618581647 | COAD | Female-baised eQTL |
| rs9388861 | chr6:130861644:T:G | - | 0.0625503501640408 | 0.031038096850875 | COAD | Female-baised eQTL |
| rs2183967 | chr6:130871649:T:C | - | 0.0612671599005943 | 0.0342925858401231 | COAD | Female-baised eQTL |
| rs9374877 | chr6:120269037:A:G | - | 0.0645206765703907 | 0.043394967954247 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs1397197 | chr6:124049490:A:G | - | 0.202551312521335 | 0.0261567767627083 | PAAD | Male-baised eQTL |
| rs9491058 | chr6:124049188:G:C | - | 0.21020033691168 | 0.0267060302525852 | PAAD | Male-baised eQTL |
| rs11757225 | chr6:124043098:A:G | - | 0.217632443081918 | 0.0304043380337327 | PAAD | Male-baised eQTL |
| rs11751997 | chr6:127734607:A:G | - | 0.0975254907988922 | 0.0329741189225004 | HNSC | Male-baised eQTL |
| rs11752750 | chr6:127734225:T:C | - | 0.0974675507863069 | 0.0332312284097909 | HNSC | Male-baised eQTL |
| rs62423855 | chr6:116329395:A:G | - | 0.155296639609526 | 0.0139985320937705 | SARC | Male-baised eQTL |
| rs62423853 | chr6:116324303:C:T | - | 0.15373960762167 | 0.0183968709844455 | SARC | Male-baised eQTL |
| rs62423856 | chr6:116330669:A:C | - | 0.15373960762167 | 0.0183968709844455 | SARC | Male-baised eQTL |
| rs144324797 | chr6:116335168:T:C | - | 0.15373960762167 | 0.0183968709844455 | SARC | Male-baised eQTL |
| rs6904424 | chr6:116339077:C:G | - | 0.15373960762167 | 0.0183968709844455 | SARC | Male-baised eQTL |
| rs138147200 | chr6:116346150:C:T | - | 0.152987977467883 | 0.0202355585116245 | SARC | Male-baised eQTL |
| rs143342467 | chr6:116346694:A:C | - | 0.152987977467883 | 0.0202355585116245 | SARC | Male-baised eQTL |
| rs7757064 | chr6:116346891:C:A | - | 0.152987977467883 | 0.0202355585116245 | SARC | Male-baised eQTL |
| rs61655621 | chr6:116348982:G:A | - | 0.152987977467883 | 0.0202355585116245 | SARC | Male-baised eQTL |
| rs58018017 | chr6:116309373:G:A | - | 0.152463922164995 | 0.0227930662048404 | SARC | Male-baised eQTL |
| rs9398466 | chr6:117841071:A:G | - | -0.057614339045304 | 0.0197511719496007 | KIRC | Male-baised eQTL |
| rs9372487 | chr6:117841044:G:T | - | -0.0571883720775983 | 0.0215429596576602 | KIRC | Male-baised eQTL |
| rs503718 | chr6:117855371:C:G | - | 0.0571550271862158 | 0.0225410518263029 | KIRC | Male-baised eQTL |
| rs9374685 | chr6:117837607:G:A | - | -0.0557848621815282 | 0.0291141982788529 | KIRC | Male-baised eQTL |
| rs473136 | chr6:117846193:A:G | - | 0.0557848621815281 | 0.0291141982788529 | KIRC | Male-baised eQTL |
| rs662405 | chr6:117854197:T:C | - | 0.0557848621815281 | 0.0291141982788529 | KIRC | Male-baised eQTL |
| rs1068779 | chr6:117857568:T:C | - | 0.0556510638317222 | 0.0336242552181906 | KIRC | Male-baised eQTL |
| rs12203409 | chr6:117836865:T:C | - | -0.0567726242747441 | 0.034396891568905 | KIRC | Male-baised eQTL |
| rs9385024 | chr6:117825673:G:A | - | -0.0566078175388018 | 0.0358030123415147 | KIRC | Male-baised eQTL |
| rs510741 | chr6:117845197:G:A | - | 0.0546844459403413 | 0.0414191481203517 | KIRC | Male-baised eQTL |
| rs647654 | chr6:117855135:G:A | - | 0.0547072341040275 | 0.0415794124560931 | KIRC | Male-baised eQTL |
| rs2139048 | chr6:117836359:T:C | - | -0.0552817803819468 | 0.0455567666775212 | KIRC | Male-baised eQTL |
| rs9387518 | chr6:117836578:A:T | - | -0.0552817803819468 | 0.0455567666775212 | KIRC | Male-baised eQTL |
| rs646738 | chr6:117855368:G:A | - | 0.0541888882588566 | 0.0465664986280614 | KIRC | Male-baised eQTL |
| rs9387517 | chr6:117828365:G:A | - | -0.0548513672058923 | 0.0489217446986465 | KIRC | Male-baised eQTL |
| rs74948997 | chr6:132738754:T:C | - | 0.186343208220029 | 0.000673284825089733 | LUAD | Male-baised eQTL |
| rs719581 | chr6:124336169:A:G | - | 0.13442680984053 | 0.00168986753842523 | LUAD | Male-baised eQTL |
| rs9388314 | chr6:124336873:A:G | - | 0.13442680984053 | 0.00168986753842523 | LUAD | Male-baised eQTL |
| rs372844931 | chr6:124344485:G:C | - | 0.133734506900305 | 0.0018233714065193 | LUAD | Male-baised eQTL |
| rs9401738 | chr6:124358985:C:A | - | 0.127482636349195 | 0.00360596305082662 | LUAD | Male-baised eQTL |
| rs9401739 | chr6:124358992:G:A | - | 0.127482636349195 | 0.00360596305082662 | LUAD | Male-baised eQTL |
| rs9388318 | chr6:124343851:C:G | - | 0.126160206944275 | 0.00635955229966782 | LUAD | Male-baised eQTL |
| rs1474994 | chr6:124365932:A:G | - | 0.12018839754396 | 0.00829288127008929 | LUAD | Male-baised eQTL |
| rs368901626 | chr6:124345577:C:T | - | 0.12290906040931 | 0.0107996150288408 | LUAD | Male-baised eQTL |
| rs370996670 | chr6:124345640:C:T | - | 0.12290906040931 | 0.0107996150288408 | LUAD | Male-baised eQTL |
| rs9401732 | chr6:124343773:T:C | - | 0.122205049815499 | 0.011831308820162 | LUAD | Male-baised eQTL |
| rs17051705 | chr6:124357025:C:G | - | 0.104391922417346 | 0.0227986035905068 | LUAD | Male-baised eQTL |
| rs9401737 | chr6:124358021:C:T | - | 0.104391922417346 | 0.0227986035905068 | LUAD | Male-baised eQTL |
| rs9375326 | chr6:124359647:G:A | - | 0.102988180583228 | 0.0289206047256906 | LUAD | Male-baised eQTL |
| rs9375327 | chr6:124370960:T:A | - | 0.107274666324561 | 0.0365760007012683 | LUAD | Male-baised eQTL |
| rs78932250 | chr6:122753415:C:A | - | 0.135760401011976 | 0.0385426865180011 | LUAD | Male-baised eQTL |
| rs2025220 | chr6:124354724:A:G | - | 0.0959312511206224 | 0.0442637806293691 | LUAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000172594 |
| CpG Site: cg12379307 | |
| Position to Gene: promoter | |
| Male Effect: - | |
| Female Effect: -0.448913558073319 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg12379307 | chr6:122788692 | promoter | -0.448913558073319 | 4.63239376775668e-19 | -0.5576326457193268 | 3.0781690340782687e-22 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs9401653 | chr6:123318192:C:T | Distant downstream | 0.0925130881707621 | 0.00460961239017898 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs1890467 | chr6:123318870:C:T | Distant downstream | 0.0925130881707621 | 0.00460961239017898 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs1431279 | chr6:123357227:G:A | Distant downstream | 0.0929592651619781 | 0.0052986458887057 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs1030554 | chr6:123357658:C:T | Distant downstream | 0.0929592651619781 | 0.0052986458887057 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs6569338 | chr6:123350448:A:G | Distant downstream | 0.0929296562690232 | 0.00534828711911138 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs3850235 | chr6:123351511:G:A | Distant downstream | 0.0929296562690232 | 0.00534828711911138 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs9375250 | chr6:123352310:G:T | Distant downstream | 0.0929296562690232 | 0.00534828711911138 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs9388220 | chr6:123314135:T:C | Distant downstream | 0.0916273049174651 | 0.00537937082609265 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs9388221 | chr6:123314213:C:G | Distant downstream | 0.0916273049174651 | 0.00537937082609265 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs6934091 | chr6:123321850:G:A | Distant downstream | 0.0916273049174651 | 0.00537937082609265 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs2317690 | chr6:123322860:T:C | Distant downstream | 0.0916273049174651 | 0.00537937082609265 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs1933902 | chr6:123330542:C:A | Distant downstream | 0.0916273049174651 | 0.00537937082609265 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs9372744 | chr6:123344801:G:A | Distant downstream | 0.0916273049174651 | 0.00537937082609265 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs9388226 | chr6:123344954:T:C | Distant downstream | 0.0916273049174651 | 0.00537937082609265 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs7774324 | chr6:123345521:G:A | Distant downstream | 0.0916273049174651 | 0.00537937082609265 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs9401662 | chr6:123347305:C:A | Distant downstream | 0.0916273049174651 | 0.00537937082609265 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs1933900 | chr6:123348008:T:C | Distant downstream | 0.0916273049174651 | 0.00537937082609265 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs1367668 | chr6:123348028:T:G | Distant downstream | 0.0916273049174651 | 0.00537937082609265 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs1933901 | chr6:123348118:A:T | Distant downstream | 0.0916273049174651 | 0.00537937082609265 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs4365953 | chr6:123362186:A:C | Distant downstream | 0.0926977676042354 | 0.00551804133553551 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs4591877 | chr6:123365714:C:T | Distant downstream | 0.0926977676042354 | 0.00551804133553551 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs2873479 | chr6:123366143:A:C | Distant downstream | 0.0926977676042354 | 0.00551804133553551 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs7769808 | chr6:123366287:T:C | Distant downstream | 0.0926977676042354 | 0.00551804133553551 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs7765003 | chr6:123368920:A:G | Distant downstream | 0.0926977676042354 | 0.00551804133553551 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs2163447 | chr6:123376438:G:A | Distant downstream | 0.0646660398619862 | 0.0136121543689101 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs989072 | chr6:123376550:C:T | Distant downstream | 0.0646660398619862 | 0.0136121543689101 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs1367674 | chr6:123380793:A:C | Distant downstream | 0.0646660398619862 | 0.0136121543689101 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs2043149 | chr6:123382639:A:G | Distant downstream | 0.0646660398619862 | 0.0136121543689101 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs57493646 | chr6:123385434:A:G | Distant downstream | 0.0640155219696389 | 0.0145197696122475 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs58131908 | chr6:123385435:G:A | Distant downstream | 0.0640155219696389 | 0.0145197696122475 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs9401664 | chr6:123363598:T:C | Distant downstream | 0.0694184775818637 | 0.0164411190577004 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs7752950 | chr6:123383917:G:T | Distant downstream | 0.0610941317272061 | 0.0269476742296651 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs1431280 | chr6:123357056:A:G | Distant downstream | 0.0652390537836559 | 0.0331963816957384 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs11154151 | chr6:123357850:T:C | Distant downstream | 0.0652390537836559 | 0.0331963816957384 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs9375251 | chr6:123358675:G:T | Distant downstream | 0.0652390537836559 | 0.0331963816957384 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs7745562 | chr6:123359973:G:C | Distant downstream | 0.0652390537836559 | 0.0331963816957384 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs6569339 | chr6:123353189:A:G | Distant downstream | 0.0652163056053292 | 0.0334684976336041 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs9398728 | chr6:123363590:C:T | Distant downstream | 0.0650026211261804 | 0.0344587018072431 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs1346919 | chr6:123398925:T:G | Distant downstream | 0.0591003424645443 | 0.0429124910509049 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs2163446 | chr6:123402041:C:T | Distant downstream | 0.0591003424645443 | 0.0429124910509049 | LGG | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs9482442 | chr6:123737600:G:A | Distant downstream | -0.0631909041835098 | 0.000694111253625513 | COAD | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs9490907 | chr6:123741027:G:A | Distant downstream | -0.065044988817501 | 0.000802106186005928 | COAD | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs7742043 | chr6:123730656:C:T | Distant downstream | 0.0530117248667758 | 0.00331552434003022 | COAD | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs10872260 | chr6:123091978:T:C | Distant downstream | -0.0727253620363689 | 0.00436861899099073 | COAD | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs7747204 | chr6:123095692:T:C | Distant downstream | -0.0656013234574696 | 0.00653621286434897 | COAD | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs59110816 | chr6:123096832:G:A | Distant downstream | -0.0656013234574696 | 0.00653621286434897 | COAD | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs7751806 | chr6:123768027:C:T | Distant downstream | -0.0472515612629445 | 0.0107830828364783 | COAD | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs9482282 | chr6:122762831:A:C | Distant upstream | 0.0389439050170943 | 0.0157767158830255 | COAD | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs12665325 | chr6:122115400:A:G | Distant upstream | 0.0421144547009363 | 0.0253062613147326 | COAD | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs1485651 | chr6:122765582:T:C | Distant upstream | 0.0377609075006288 | 0.0255896058896784 | COAD | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs9490547 | chr6:122766994:G:C | Distant upstream | 0.0377609075006288 | 0.0255896058896784 | COAD | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs1485647 | chr6:122767541:G:A | Distant upstream | 0.0377609075006288 | 0.0255896058896784 | COAD | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs7756582 | chr6:122927045:T:G | Distant downstream | -0.0380501263578244 | 0.0294711644606534 | COAD | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs342636 | chr6:123724836:G:A | Distant downstream | 0.0410795967421151 | 0.0316006223272732 | COAD | Female-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs4579373 | chr6:123103197:T:C | Distant downstream | -0.0595918587003647 | 0.0397069627742421 | COAD | Female-baised sQTL |
| exon_skip_454011 | chr6:122801309:122801406 | Frame-shift | rs13199871 | chr6:123510527:C:G | Distant downstream | -0.0899349168971508 | 0.010150880617535 | LIHC | Female-baised sQTL |
| exon_skip_454011 | chr6:122801309:122801406 | Frame-shift | rs35786400 | chr6:123498016:C:T | Distant downstream | -0.0831893335742375 | 0.0259658623075908 | LIHC | Female-baised sQTL |
| exon_skip_454011 | chr6:122801309:122801406 | Frame-shift | rs62420507 | chr6:123505424:G:A | Distant downstream | -0.0829944949540612 | 0.0273588900261718 | LIHC | Female-baised sQTL |
| exon_skip_454011 | chr6:122801309:122801406 | Frame-shift | rs7750711 | chr6:123506530:C:A | Distant downstream | -0.0829944949540612 | 0.0273588900261718 | LIHC | Female-baised sQTL |
| exon_skip_454011 | chr6:122801309:122801406 | Frame-shift | rs7751031 | chr6:123506726:C:T | Distant downstream | -0.0829944949540612 | 0.0273588900261718 | LIHC | Female-baised sQTL |
| exon_skip_454011 | chr6:122801309:122801406 | Frame-shift | rs13218429 | chr6:123508409:C:G | Distant downstream | -0.0829944949540612 | 0.0273588900261718 | LIHC | Female-baised sQTL |
| exon_skip_454011 | chr6:122801309:122801406 | Frame-shift | rs75584284 | chr6:123509267:C:T | Distant downstream | -0.0829944949540612 | 0.0273588900261718 | LIHC | Female-baised sQTL |
| exon_skip_454011 | chr6:122801309:122801406 | Frame-shift | rs13194024 | chr6:123521498:C:T | Distant downstream | -0.0805607093924767 | 0.0314629956418384 | LIHC | Female-baised sQTL |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs1259 | chr6:123218540:T:C | Distant downstream | -0.0289701572271174 | 0.0214078466534479 | HNSC | Male-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs4243489 | chr6:123224736:T:C | Distant downstream | -0.0285594027738321 | 0.0240876286608022 | HNSC | Male-baised sQTL |
| exon_skip_454019 | chr6:122806232:122806357 | Frame-shift | rs4351282 | chr6:123224871:T:C | Distant downstream | -0.0285594027738321 | 0.0240876286608022 | HNSC | Male-baised sQTL |
| exon_skip_454011 | chr6:122801309:122801406 | Frame-shift | rs2873534 | chr6:123320306:A:T | Distant downstream | -0.029420144193283 | 0.0277215215572717 | HNSC | Male-baised sQTL |
| exon_skip_454011 | chr6:122801309:122801406 | Frame-shift | rs9490587 | chr6:122906198:T:C | Distant downstream | -0.030329472111401 | 0.0384446505362824 | HNSC | Male-baised sQTL |
| exon_skip_454011 | chr6:122801309:122801406 | Frame-shift | rs138120151 | chr6:122905967:C:T | Distant downstream | -0.0295705435380427 | 0.0486870583956209 | HNSC | Male-baised sQTL |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of SMPDL3A |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000172594 | SMPDL3A | C0014175 | Endometriosis | 1 | CTD_human |
| ENSG00000172594 | SMPDL3A | C0269102 | Endometrioma | 1 | CTD_human |
