|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
| |
|
Gene: ENSG00000172456 |
Summary for FGGY |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000172456 | Gene symbol | FGGY |
| Gene name | FGGY carbohydrate kinase domain containing | |
| HGNC | 25610 | |
| Entrez ID | 55277 | |
| Gene type | protein_coding | |
| Synonyms | FGGY|FLJ10986 | |
| UniProtAcc | Q96C11 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for FGGY |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| FGGY | 1.16e+03 | -2.30e+00 | 2.71e-01 | -8.51e+00 | 1.80e-17 | 1.20e-15 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| FGGY | 1.72e+03 | 2.54e+00 | 6.09e-01 | 4.18e+00 | 2.94e-05 | 1.66e-04 | READ |
Top |
Sex-biased somatic mutation for FGGY |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for FGGY |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
Top |
Exon skipping events with PSI in TCGA for FGGY |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
 |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| CHOL | exon_skip_6828 | 7.94e-01 | 9.13e-01 | -2.96e+00 | 3.09e-03 | 1.32e-02 | -1.19e-01 |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| READ | exon_skip_6828 | 7.82e-01 | 8.88e-01 | -3.53e+00 | 4.22e-04 | 4.93e-03 | -1.06e-01 |
Top |
RNA A-to-I editing events in TCGA for FGGY |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for FGGY |
| TFs related to FGGY. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| ACC | ZNF418 | FGGY | 3.77e+00 | 9.82e-01 | 2.15e+00 | 2.95e-04 | Male-biased |
| CHOL | POU4F3 | FGGY | 2.89e+00 | 5.24e-03 | 3.97e+00 | 9.82e-01 | Female-biased |
| CHOL | SKOR2 | FGGY | 3.38e+00 | 1.16e-02 | 4.27e+00 | 9.80e-01 | Female-biased |
| FGGY related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for FGGY |
| RBPs related to ES in FGGY. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| THYM | KHDRBS2 | exon_skip_6840 | 1.07e+01 | 9.97e-01 | 1.02e+01 | 2.18e-03 | Male-biased |
| CHOL | PABPN1 | exon_skip_6790 | 9.52e+00 | 9.91e-01 | 9.05e+00 | 5.98e-03 | Male-biased |
| GBM | KHDRBS2 | exon_skip_6840 | 1.01e+01 | 1.80e-03 | 1.06e+01 | 9.97e-01 | Female-biased |
| KIRC | Fusip1 | exon_skip_6785 | 7.15e+00 | 9.86e-01 | 6.71e+00 | 1.97e-03 | Male-biased |
| KIRC | SAMD4A | exon_skip_6778 | 8.35e+00 | 6.02e-03 | 8.71e+00 | 9.89e-01 | Female-biased |
| SARC | RBMS1 | exon_skip_6809 | 1.38e+01 | 1.75e-02 | 1.41e+01 | 9.82e-01 | Female-biased |
| FGGY related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs75535702 | chr1:49373978:T:C | - | 0.157027413371936 | 0.00012106924661517 | HNSC | Female-baised eQTL |
| rs75518537 | chr1:49364235:A:T | - | 0.156802385334429 | 0.000124605860828403 | HNSC | Female-baised eQTL |
| rs11806465 | chr1:49381486:C:T | - | 0.156802385334429 | 0.000124605860828403 | HNSC | Female-baised eQTL |
| rs77728486 | chr1:49397791:C:T | - | 0.156802385334429 | 0.000124605860828403 | HNSC | Female-baised eQTL |
| rs74816548 | chr1:49424644:G:A | - | 0.156802385334429 | 0.000124605860828403 | HNSC | Female-baised eQTL |
| rs75842935 | chr1:50024506:C:T | - | 0.143440900909993 | 0.000954885421116365 | HNSC | Female-baised eQTL |
| rs145130591 | chr1:50034310:C:T | - | 0.143440900909993 | 0.000954885421116365 | HNSC | Female-baised eQTL |
| rs145046492 | chr1:49611542:A:T | - | 0.143121155859535 | 0.00102369583434659 | HNSC | Female-baised eQTL |
| rs76663574 | chr1:49545028:T:C | - | 0.14288167479444 | 0.00105394586016736 | HNSC | Female-baised eQTL |
| rs10437056 | chr1:49557007:G:A | - | 0.14288167479444 | 0.00105394586016736 | HNSC | Female-baised eQTL |
| rs114682111 | chr1:49557223:G:T | - | 0.14288167479444 | 0.00105394586016736 | HNSC | Female-baised eQTL |
| rs7355222 | chr1:49566372:C:T | - | 0.142847608186442 | 0.00106592605438182 | HNSC | Female-baised eQTL |
| rs79411382 | chr1:49572303:G:A | - | 0.142847608186442 | 0.00106592605438182 | HNSC | Female-baised eQTL |
| rs76664691 | chr1:49585546:C:T | - | 0.142847608186442 | 0.00106592605438182 | HNSC | Female-baised eQTL |
| rs28641917 | chr1:49591281:G:T | - | 0.142847608186442 | 0.00106592605438182 | HNSC | Female-baised eQTL |
| rs7546901 | chr1:49592678:C:A | - | 0.142847608186442 | 0.00106592605438182 | HNSC | Female-baised eQTL |
| rs78951692 | chr1:49593061:C:T | - | 0.142847608186442 | 0.00106592605438182 | HNSC | Female-baised eQTL |
| rs77009066 | chr1:49596014:T:C | - | 0.142847608186442 | 0.00106592605438182 | HNSC | Female-baised eQTL |
| rs146635217 | chr1:49598682:A:G | - | 0.142847608186442 | 0.00106592605438182 | HNSC | Female-baised eQTL |
| rs79674944 | chr1:49637782:A:G | - | 0.135251111337716 | 0.00233858118207569 | HNSC | Female-baised eQTL |
| rs76124443 | chr1:49652358:A:T | - | 0.135251111337716 | 0.00233858118207569 | HNSC | Female-baised eQTL |
| rs193080162 | chr1:49658091:T:A | - | 0.135251111337716 | 0.00233858118207569 | HNSC | Female-baised eQTL |
| rs78726266 | chr1:49665110:T:C | - | 0.135251111337716 | 0.00233858118207569 | HNSC | Female-baised eQTL |
| rs78607346 | chr1:49669809:G:A | - | 0.135251111337716 | 0.00233858118207569 | HNSC | Female-baised eQTL |
| rs76879179 | chr1:49676894:A:G | - | 0.135251111337716 | 0.00233858118207569 | HNSC | Female-baised eQTL |
| rs78118207 | chr1:49677596:C:T | - | 0.135251111337716 | 0.00233858118207569 | HNSC | Female-baised eQTL |
| rs77326725 | chr1:49680647:T:A | - | 0.135251111337716 | 0.00233858118207569 | HNSC | Female-baised eQTL |
| rs10159286 | chr1:49695277:T:C | - | 0.135251111337716 | 0.00233858118207569 | HNSC | Female-baised eQTL |
| rs75355801 | chr1:49720079:T:C | - | 0.135251111337716 | 0.00233858118207569 | HNSC | Female-baised eQTL |
| rs115959871 | chr1:49738094:G:A | - | 0.135251111337716 | 0.00233858118207569 | HNSC | Female-baised eQTL |
| rs115330456 | chr1:49751339:A:G | - | 0.135251111337716 | 0.00233858118207569 | HNSC | Female-baised eQTL |
| rs78969676 | chr1:49758357:A:G | - | 0.135251111337716 | 0.00233858118207569 | HNSC | Female-baised eQTL |
| rs77833571 | chr1:49759576:T:C | - | 0.135251111337716 | 0.00233858118207569 | HNSC | Female-baised eQTL |
| rs76516220 | chr1:49762097:A:C | - | 0.135251111337716 | 0.00233858118207569 | HNSC | Female-baised eQTL |
| rs17318954 | chr1:63161240:C:A | - | 0.142980546981623 | 0.00274972976559221 | HNSC | Female-baised eQTL |
| rs375899 | chr1:49316653:A:G | - | 0.116302115595019 | 0.0172335225888722 | HNSC | Female-baised eQTL |
| rs11808682 | chr1:49328400:A:C | - | 0.116302115595019 | 0.0172335225888722 | HNSC | Female-baised eQTL |
| rs74364708 | chr1:49336343:T:C | - | 0.116302115595019 | 0.0172335225888722 | HNSC | Female-baised eQTL |
| rs77095013 | chr1:49355576:C:T | - | 0.116302115595019 | 0.0172335225888722 | HNSC | Female-baised eQTL |
| rs80187112 | chr1:49802802:G:A | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs74575646 | chr1:49817764:T:G | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs11805593 | chr1:49836044:C:T | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs75625646 | chr1:49855520:G:A | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs78849926 | chr1:49856338:A:G | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs79361784 | chr1:49857172:C:T | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs76231699 | chr1:49891499:A:G | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs77577435 | chr1:49891598:G:A | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs77357960 | chr1:49892429:C:A | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs6683161 | chr1:49895823:C:T | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs115403799 | chr1:49896745:G:C | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs78019440 | chr1:49897760:T:C | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs79794233 | chr1:49903836:T:C | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs79998711 | chr1:49906558:T:C | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs79869815 | chr1:49914926:C:A | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs142566495 | chr1:49916671:T:C | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs116439991 | chr1:49923467:C:T | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs9988530 | chr1:49924019:G:A | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs11803306 | chr1:49925468:G:T | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs74543276 | chr1:49934302:G:C | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs76976294 | chr1:49953405:C:T | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs144786987 | chr1:49958281:C:T | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs148898405 | chr1:49972175:C:G | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs76446960 | chr1:49973980:A:G | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs74660434 | chr1:49981038:T:A | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs77413772 | chr1:49981495:T:C | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs61749053 | chr1:49995323:T:C | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs115638047 | chr1:49996461:A:G | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs78627746 | chr1:50001586:G:A | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs7537735 | chr1:50009422:G:A | - | 0.110886596302275 | 0.0261433439328107 | HNSC | Female-baised eQTL |
| rs28695358 | chr1:49982062:C:A | - | 0.110588039598917 | 0.027222887252311 | HNSC | Female-baised eQTL |
| rs9651187 | chr1:57046672:C:A | - | 0.138069113125494 | 0.0418809144061313 | HNSC | Female-baised eQTL |
| rs2498968 | chr1:61969469:G:A | - | -0.0637990496505929 | 0.0126836520191447 | THCA | Female-baised eQTL |
| rs2151124 | chr1:61954631:T:C | - | -0.0604509436974965 | 0.0264171511885977 | THCA | Female-baised eQTL |
| rs2482888 | chr1:61963544:T:C | - | -0.0596680052832092 | 0.0313502931247427 | THCA | Female-baised eQTL |
| rs2482889 | chr1:61964673:T:C | - | -0.0590867525028068 | 0.0383206784704843 | THCA | Female-baised eQTL |
| rs2482886 | chr1:61962039:T:C | - | -0.0587420863652415 | 0.0390610424699362 | THCA | Female-baised eQTL |
| rs10889779 | chr1:68544250:C:T | - | 0.136988646319383 | 0.000438757347150165 | SARC | Female-baised eQTL |
| rs11209321 | chr1:68556849:A:T | - | 0.136988646319383 | 0.000438757347150165 | SARC | Female-baised eQTL |
| rs9887872 | chr1:68522436:T:C | - | 0.134360659628071 | 0.000671440829042331 | SARC | Female-baised eQTL |
| rs10889781 | chr1:68553819:G:A | - | 0.132651023199921 | 0.000721360273759828 | SARC | Female-baised eQTL |
| rs10889777 | chr1:68533556:A:G | - | 0.132103044888711 | 0.000777918600577623 | SARC | Female-baised eQTL |
| rs11209317 | chr1:68533922:A:G | - | 0.132103044888711 | 0.000777918600577623 | SARC | Female-baised eQTL |
| rs12405366 | chr1:68542052:C:T | - | 0.131865920703118 | 0.000830546874040406 | SARC | Female-baised eQTL |
| rs1041046 | chr1:68536975:C:T | - | 0.127808442774419 | 0.00133996535886409 | SARC | Female-baised eQTL |
| rs10889775 | chr1:68519327:A:T | - | 0.125287797212617 | 0.00205326866347683 | SARC | Female-baised eQTL |
| rs12027547 | chr1:68525725:C:A | - | 0.123488044072333 | 0.00228523651663451 | SARC | Female-baised eQTL |
| rs12041567 | chr1:68516652:T:C | - | 0.101024363292407 | 0.00530155922578575 | SARC | Female-baised eQTL |
| rs10749783 | chr1:68492408:C:T | - | 0.109643658664074 | 0.00993210146317281 | SARC | Female-baised eQTL |
| rs10789263 | chr1:68483456:T:C | - | 0.0998543665388902 | 0.0202784974443131 | SARC | Female-baised eQTL |
| rs877494 | chr1:59971252:C:G | - | -0.0655545556181596 | 0.0437108916254356 | SARC | Female-baised eQTL |
| rs12736035 | chr1:52746766:C:T | - | 0.234811366254054 | 0.00553404432163367 | KIRP | Female-baised eQTL |
| rs56013710 | chr1:52868243:C:T | - | 0.195230807350724 | 0.00779649334236522 | KIRP | Female-baised eQTL |
| rs72897325 | chr1:52868611:C:T | - | 0.195230807350724 | 0.00779649334236522 | KIRP | Female-baised eQTL |
| rs142760113 | chr1:52870154:G:T | - | 0.195230807350724 | 0.00779649334236522 | KIRP | Female-baised eQTL |
| rs76341684 | chr1:52734976:G:A | - | 0.219824190347922 | 0.018570426959767 | KIRP | Female-baised eQTL |
| rs79781432 | chr1:52738250:G:T | - | 0.219824190347922 | 0.018570426959767 | KIRP | Female-baised eQTL |
| rs12726936 | chr1:52739894:C:T | - | 0.219824190347922 | 0.018570426959767 | KIRP | Female-baised eQTL |
| rs797901 | chr1:53740605:G:C | - | 0.131042539555623 | 0.0212353497617966 | KIRP | Female-baised eQTL |
| rs4578160 | chr1:52875862:T:G | - | 0.18669128829699 | 0.0288027744753862 | KIRP | Female-baised eQTL |
| rs66483567 | chr1:69758556:G:A | - | 0.12823458475297 | 0.0299314369306458 | KIRP | Female-baised eQTL |
| rs11584332 | chr1:52886183:C:T | - | 0.183592613954001 | 0.0364002613583269 | KIRP | Female-baised eQTL |
| rs12407496 | chr1:69760442:T:C | - | 0.122485887857717 | 0.04614947626184 | KIRP | Female-baised eQTL |
| rs12133825 | chr1:58363427:C:T | - | 0.129516201677831 | 0.0383559725767168 | LUSC | Female-baised eQTL |
| rs11589326 | chr1:66817863:G:C | - | 0.0611493622637951 | 0.00047680082523327 | LUAD | Female-baised eQTL |
| rs3005891 | chr1:56316667:A:G | - | -0.0619137702152232 | 0.000583807994806422 | LUAD | Female-baised eQTL |
| rs17121177 | chr1:60879337:T:C | - | 0.0574019432548978 | 0.00105827719077718 | LUAD | Female-baised eQTL |
| rs478665 | chr1:65049850:A:G | - | 0.0620796523684378 | 0.00197994875767905 | LUAD | Female-baised eQTL |
| rs855327 | chr1:63641958:C:T | - | 0.0520951805958999 | 0.00205169538925296 | LUAD | Female-baised eQTL |
| rs1180964 | chr1:54752581:G:A | - | 0.0386149640382224 | 0.0047882340885437 | LUAD | Female-baised eQTL |
| rs6697048 | chr1:55236620:A:G | - | 0.0569549318794775 | 0.00517892000279825 | LUAD | Female-baised eQTL |
| rs72668400 | chr1:56826076:C:G | - | 0.0442733054352533 | 0.00534983504888701 | LUAD | Female-baised eQTL |
| rs58333395 | chr1:52596814:T:C | - | 0.0587027919440495 | 0.00540893750269681 | LUAD | Female-baised eQTL |
| rs4915953 | chr1:64233911:T:G | - | 0.0428837722407387 | 0.0057562983296923 | LUAD | Female-baised eQTL |
| rs59784071 | chr1:63658639:T:A | - | 0.0483628713620308 | 0.0069544464763437 | LUAD | Female-baised eQTL |
| rs35870185 | chr1:60991750:C:T | - | 0.0515577886873184 | 0.013876166474743 | LUAD | Female-baised eQTL |
| rs12137176 | chr1:56819840:G:C | - | 0.0388264194846207 | 0.0173311468960916 | LUAD | Female-baised eQTL |
| rs67942738 | chr1:55222480:A:G | - | 0.0499335680414912 | 0.018211555011913 | LUAD | Female-baised eQTL |
| rs7542558 | chr1:55224113:A:G | - | 0.0499335680414912 | 0.018211555011913 | LUAD | Female-baised eQTL |
| rs7539908 | chr1:53711606:T:C | - | 0.0298008743937547 | 0.0185268876907465 | LUAD | Female-baised eQTL |
| rs11586998 | chr1:64249021:C:T | - | 0.0347248730346565 | 0.0205807139567057 | LUAD | Female-baised eQTL |
| rs17111728 | chr1:55225711:T:C | - | 0.0494968871178123 | 0.0226919198642539 | LUAD | Female-baised eQTL |
| rs111847453 | chr1:55227887:T:C | - | 0.0494968871178123 | 0.0226919198642539 | LUAD | Female-baised eQTL |
| rs111291700 | chr1:55228110:A:G | - | 0.0494968871178123 | 0.0226919198642539 | LUAD | Female-baised eQTL |
| rs112811352 | chr1:55228387:C:G | - | 0.0494968871178123 | 0.0226919198642539 | LUAD | Female-baised eQTL |
| rs112347583 | chr1:55228413:T:C | - | 0.0494968871178123 | 0.0226919198642539 | LUAD | Female-baised eQTL |
| rs113515274 | chr1:55228821:G:A | - | 0.0494968871178123 | 0.0226919198642539 | LUAD | Female-baised eQTL |
| rs1996213 | chr1:64413652:G:A | - | -0.0384248409237122 | 0.0227742591820215 | LUAD | Female-baised eQTL |
| rs483317 | chr1:65050348:G:C | - | 0.0454150955957508 | 0.0242882592046014 | LUAD | Female-baised eQTL |
| rs2375464 | chr1:64405292:A:G | - | -0.0371384121882924 | 0.026961893618571 | LUAD | Female-baised eQTL |
| rs6703627 | chr1:64403022:G:C | - | -0.0371631562567184 | 0.0270483064519894 | LUAD | Female-baised eQTL |
| rs4915955 | chr1:64243533:C:T | - | 0.0333900365204151 | 0.0283745046953751 | LUAD | Female-baised eQTL |
| rs11579130 | chr1:58637796:G:A | - | 0.0517889648966829 | 0.0297456617207379 | LUAD | Female-baised eQTL |
| rs11206923 | chr1:56817508:A:G | - | 0.0340683923877778 | 0.030225535851849 | LUAD | Female-baised eQTL |
| rs17126246 | chr1:64228218:G:A | - | 0.0340857531900922 | 0.0338742935073559 | LUAD | Female-baised eQTL |
| rs17126247 | chr1:64228484:G:A | - | 0.0340857531900922 | 0.0338742935073559 | LUAD | Female-baised eQTL |
| rs33994100 | chr1:64239288:T:C | - | 0.0326284775658542 | 0.0352021817621105 | LUAD | Female-baised eQTL |
| rs12564589 | chr1:64240896:A:G | - | 0.0326284775658542 | 0.0352021817621105 | LUAD | Female-baised eQTL |
| rs11208387 | chr1:64241060:T:C | - | 0.0326284775658542 | 0.0352021817621105 | LUAD | Female-baised eQTL |
| rs4915954 | chr1:64235720:G:A | - | 0.0326101459086368 | 0.0355979427289598 | LUAD | Female-baised eQTL |
| rs1390484 | chr1:64365709:T:C | - | -0.0300576374193929 | 0.036169753997893 | LUAD | Female-baised eQTL |
| rs12084638 | chr1:56818966:G:C | - | 0.0342375768895128 | 0.0362774250218836 | LUAD | Female-baised eQTL |
| rs11206924 | chr1:56818631:A:T | - | 0.0341788940870632 | 0.036485963315529 | LUAD | Female-baised eQTL |
| rs10489899 | chr1:64222390:G:A | - | 0.0337778525272332 | 0.0369827833310981 | LUAD | Female-baised eQTL |
| rs1027421 | chr1:64222952:T:C | - | 0.0337778525272332 | 0.0369827833310981 | LUAD | Female-baised eQTL |
| rs10889019 | chr1:56817744:G:T | - | 0.033596106938867 | 0.0373100231846944 | LUAD | Female-baised eQTL |
| rs61774738 | chr1:55541005:G:A | - | 0.0478673548070592 | 0.0380151383768962 | LUAD | Female-baised eQTL |
| rs662437 | chr1:63882667:T:C | - | -0.0413918577988393 | 0.0444838192398565 | LUAD | Female-baised eQTL |
| rs2994571 | chr1:56295959:T:G | - | 0.0373252880522694 | 0.0449530492578226 | LUAD | Female-baised eQTL |
| rs17113672 | chr1:56297918:T:C | - | 0.0373252880522694 | 0.0449530492578226 | LUAD | Female-baised eQTL |
| rs11590092 | chr1:56300212:G:A | - | 0.0373252880522694 | 0.0449530492578226 | LUAD | Female-baised eQTL |
| rs6664002 | chr1:56286845:C:G | - | 0.0385924500671612 | 0.0463668530418049 | LUAD | Female-baised eQTL |
| rs72672230 | chr1:58519793:T:C | - | 0.0485670970222996 | 0.0478563049849102 | LUAD | Female-baised eQTL |
| rs72920772 | chr1:64233302:C:T | - | 0.0302114615303172 | 0.0485657787828896 | LUAD | Female-baised eQTL |
| rs78003437 | chr1:59401948:A:C | gene | 0.108052295663064 | 0.0175715671733307 | COAD | Female-baised eQTL |
| rs75150669 | chr1:59403532:C:T | gene | 0.108052295663064 | 0.0175715671733307 | COAD | Female-baised eQTL |
| rs78044885 | chr1:59404346:A:G | gene | 0.108735263927734 | 0.0189065271973326 | COAD | Female-baised eQTL |
| rs76546697 | chr1:59416037:T:G | gene | 0.0995196460337829 | 0.0291114334934507 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs11209400 | chr1:69202753:G:T | - | 0.0309797046236599 | 0.0485631731449997 | KIRC | Male-baised eQTL |
| rs72676218 | chr1:61882814:C:T | - | 0.0670338876698499 | 0.0129798543354332 | BLCA | Male-baised eQTL |
| rs72676223 | chr1:61887078:C:T | - | 0.0662993672041519 | 0.0149633555170881 | BLCA | Male-baised eQTL |
| rs72676225 | chr1:61887311:G:A | - | 0.0662993672041519 | 0.0149633555170881 | BLCA | Male-baised eQTL |
| rs12033338 | chr1:61891615:A:T | - | 0.0661555873545864 | 0.015468307198742 | BLCA | Male-baised eQTL |
| rs12030305 | chr1:61895491:G:A | - | 0.0661555873545864 | 0.015468307198742 | BLCA | Male-baised eQTL |
| rs12042410 | chr1:61894201:C:T | - | 0.0660953143742705 | 0.0156092634790222 | BLCA | Male-baised eQTL |
| rs17374803 | chr1:60795213:C:T | - | 0.0876577615119839 | 4.39635930808894e-05 | LUAD | Male-baised eQTL |
| rs72678785 | chr1:60801348:G:T | - | 0.0817125367380522 | 9.62814150538875e-05 | LUAD | Male-baised eQTL |
| rs11590819 | chr1:53132326:G:A | - | 0.0763488502917069 | 0.000633642874579566 | LUAD | Male-baised eQTL |
| rs7515350 | chr1:60853772:A:G | - | 0.074961480409872 | 0.00111394061356589 | LUAD | Male-baised eQTL |
| rs1749509 | chr1:69604909:C:T | - | 0.070375857211583 | 0.00230961135025518 | LUAD | Male-baised eQTL |
| rs12130100 | chr1:60821180:A:T | - | 0.0625434105361493 | 0.0026197339691411 | LUAD | Male-baised eQTL |
| rs72678790 | chr1:60825494:A:G | - | 0.0586222680644438 | 0.0136688378247494 | LUAD | Male-baised eQTL |
| rs140233978 | chr1:53945795:C:A | - | 0.0641615126820382 | 0.0198253728050876 | LUAD | Male-baised eQTL |
| rs113876827 | chr1:53947843:C:T | - | 0.0641615126820382 | 0.0198253728050876 | LUAD | Male-baised eQTL |
| rs6698321 | chr1:53996581:T:C | - | -0.0627214343815897 | 0.0220611558658163 | LUAD | Male-baised eQTL |
| rs17356748 | chr1:61377671:C:G | - | 0.0553191942309021 | 0.0225070654160515 | LUAD | Male-baised eQTL |
| rs4475694 | chr1:53977234:A:G | - | -0.0624274043598524 | 0.0235611804463107 | LUAD | Male-baised eQTL |
| rs6697447 | chr1:53981254:T:C | - | -0.0624274043598524 | 0.0235611804463107 | LUAD | Male-baised eQTL |
| rs7535941 | chr1:53968511:G:T | - | 0.0527935409132372 | 0.0261139094416455 | LUAD | Male-baised eQTL |
| rs77840912 | chr1:53942878:C:T | - | 0.0618180708472252 | 0.0266181020737783 | LUAD | Male-baised eQTL |
| rs1924569 | chr1:58335834:C:T | - | 0.0395324383849784 | 0.0340224092910553 | LUAD | Male-baised eQTL |
| rs72906810 | chr1:50991528:A:G | - | 0.102360989791497 | 0.00646121107695756 | COAD | Male-baised eQTL |
| rs116475050 | chr1:50977717:G:C | - | 0.10196898168209 | 0.00676191902231974 | COAD | Male-baised eQTL |
| rs72906804 | chr1:50984472:A:G | - | 0.10196898168209 | 0.00676191902231974 | COAD | Male-baised eQTL |
| rs72906805 | chr1:50984773:G:A | - | 0.10196898168209 | 0.00676191902231974 | COAD | Male-baised eQTL |
| rs6694036 | chr1:50986396:T:A | - | 0.10196898168209 | 0.00676191902231974 | COAD | Male-baised eQTL |
| rs59595057 | chr1:51027756:A:G | - | 0.099326032019842 | 0.00813993900722197 | COAD | Male-baised eQTL |
| rs10888713 | chr1:50997752:A:T | - | 0.0976040623632565 | 0.0100157686002401 | COAD | Male-baised eQTL |
| rs3176468 | chr1:50973209:T:C | - | 0.0906021698405539 | 0.0202400889245078 | COAD | Male-baised eQTL |
| rs12755468 | chr1:61822639:A:T | - | 0.0636509711295213 | 0.0261414691959807 | COAD | Male-baised eQTL |
| rs3176466 | chr1:50972693:C:T | - | 0.0850018826024877 | 0.0263539840358928 | COAD | Male-baised eQTL |
| rs12855 | chr1:50974421:C:T | - | 0.0850018826024877 | 0.0263539840358928 | COAD | Male-baised eQTL |
| rs11207850 | chr1:61877699:C:T | - | -0.0579274422734982 | 0.0332785320193286 | COAD | Male-baised eQTL |
| rs1414277 | chr1:60943392:T:C | - | 0.0634788931125975 | 0.0356983350276549 | COAD | Male-baised eQTL |
| rs2782549 | chr1:61290762:G:T | - | -0.0547676804083153 | 0.0396101444063363 | COAD | Male-baised eQTL |
| rs1360149 | chr1:56903541:C:G | - | 0.0527035313880141 | 0.0414120935308818 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000172456 |
| CpG Site: cg19773937 | |
| Position to Gene: gene | |
| Male Effect: -0.116355911695929 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg19773937 | chr1:59750959 | gene | -0.116355911695929 | 6.34516201075242e-07 | -0.398337474762056 | 1.1446218040051102e-09 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_6809 | chr1:59638227:59638375 | Frame-shift | rs3754203 | chr1:59858281:G:T | Distant downstream | -0.0739895619690305 | 0.011742438688132 | HNSC | Female-baised sQTL |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of FGGY |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000172456 | FGGY | C0028754 | Obesity | 1 | CTD_human |
| ENSG00000172456 | FGGY | C0043094 | Weight Gain | 1 | CTD_human |
