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Gene: ENSG00000171522 |
Summary for PTGER4 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000171522 | Gene symbol | PTGER4 |
| Gene name | prostaglandin E receptor 4 | |
| HGNC | 9596 | |
| Entrez ID | 5734 | |
| Gene type | protein_coding | |
| Synonyms | PTGER4|EP4 | |
| UniProtAcc | P35408 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| ENSG00000171522 | PTGER4 | DB00917 | Dinoprostone | SmallMoleculeDrug |
| ENSG00000171522 | PTGER4 | DB00929 | Misoprostol | SmallMoleculeDrug |
| ENSG00000171522 | PTGER4 | DB09211 | Limaprost | SmallMoleculeDrug |
| ENSG00000171522 | PTGER4 | DB11113 | Castor oil | BiotechDrug |
| ENSG00000171522 | PTGER4 | DB12836 | Grapiprant | SmallMoleculeDrug |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for PTGER4 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| PTGER4 | 5.75e+02 | -1.04e+00 | 2.92e-01 | -3.56e+00 | 3.77e-04 | 5.58e-03 | BRCA |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| PTGER4 | 8.98e+02 | -1.25e+00 | 4.29e-01 | -2.92e+00 | 3.47e-03 | 9.67e-03 | BLCA |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| PTGER4 | 7.26e+02 | -1.12e+00 | 1.88e-01 | -5.94e+00 | 2.80e-09 | 1.51e-08 | KIRC |
| PTGER4 | 6.02e+02 | -1.09e+00 | 2.53e-01 | -4.30e+00 | 1.74e-05 | 1.31e-04 | HNSC |
| PTGER4 | 1.87e+03 | -1.12e+00 | 3.54e-01 | -3.16e+00 | 1.60e-03 | 8.06e-03 | STAD |
| PTGER4 | 6.70e+02 | -1.44e+00 | 9.66e-02 | -1.49e+01 | 6.13e-50 | 6.24e-49 | BRCA |
| PTGER4 | 9.91e+02 | -1.52e+00 | 3.25e-01 | -4.69e+00 | 2.69e-06 | 2.06e-05 | READ |
Top |
Sex-biased somatic mutation for PTGER4 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for PTGER4 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg04790357 | chr5:40680314 | CGI:chr5:40679400-40681979 | UTR,promoter,exon,gene body | 1.20e-01 | 2.92e-01 | -2.71e+00 | 6.63e-03 | 2.28e-02 | -1.72e-01 |
| BRCA | cg04824304 | chr5:40680448 | CGI:chr5:40679400-40681979 | UTR,promoter,exon,gene body | 8.41e-02 | 1.85e-01 | -2.57e+00 | 1.01e-02 | 2.68e-02 | -1.01e-01 |
| BRCA | cg26597539 | chr5:40680568 | CGI:chr5:40679400-40681979 | promoter,gene body | 2.08e-01 | 3.77e-01 | -2.52e+00 | 1.18e-02 | 2.84e-02 | -1.69e-01 |
| KICH | cg04092800 | chr5:40681342 | CGI:chr5:40679400-40681979 | promoter,exon,CDS,gene body | 2.89e-01 | 4.11e-01 | -2.29e+00 | 2.20e-02 | 3.86e-02 | -1.22e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg05971966 | chr5:40681035 | CGI:chr5:40679400-40681979 | promoter,exon,CDS,gene body | 1.67e-01 | 5.10e-02 | 2.25e+00 | 2.46e-02 | 2.66e-02 | 1.16e-01 |
| LUAD | cg26597539 | chr5:40680568 | CGI:chr5:40679400-40681979 | promoter,gene body | 2.24e-01 | 7.83e-02 | 2.96e+00 | 3.12e-03 | 5.04e-03 | 1.46e-01 |
| THCA | cg04092800 | chr5:40681342 | CGI:chr5:40679400-40681979 | promoter,exon,CDS,gene body | 5.13e-01 | 3.91e-01 | 1.96e+00 | 4.98e-02 | 4.98e-02 | 1.22e-01 |
| HNSC | cg26597539 | chr5:40680568 | CGI:chr5:40679400-40681979 | promoter,gene body | 1.42e-01 | 3.59e-02 | 3.08e+00 | 2.08e-03 | 3.37e-03 | 1.06e-01 |
| LUSC | cg05971966 | chr5:40681035 | CGI:chr5:40679400-40681979 | promoter,exon,CDS,gene body | 4.33e-01 | 1.06e-01 | 2.35e+00 | 1.90e-02 | 2.29e-02 | 3.27e-01 |
| BLCA | cg04092800 | chr5:40681342 | CGI:chr5:40679400-40681979 | promoter,exon,CDS,gene body | 3.01e-01 | 4.03e-01 | -2.04e+00 | 4.14e-02 | 4.32e-02 | -1.02e-01 |
| ESCA | cg04092800 | chr5:40681342 | CGI:chr5:40679400-40681979 | promoter,exon,CDS,gene body | 4.04e-01 | 2.28e-01 | 2.35e+00 | 1.86e-02 | 3.98e-02 | 1.76e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg05971966 | chr5:40681035 | CGI:chr5:40679400-40681979 | promoter,exon,CDS,gene body | 4.81e-01 | 2.51e-01 | 8.66e+00 | 4.81e-18 | 2.22e-17 | 2.30e-01 |
| BRCA | cg26597539 | chr5:40680568 | CGI:chr5:40679400-40681979 | promoter,gene body | 2.08e-01 | 6.37e-02 | 5.58e+00 | 2.37e-08 | 5.13e-08 | 1.44e-01 |
| COAD | cg04092800 | chr5:40681342 | CGI:chr5:40679400-40681979 | promoter,exon,CDS,gene body | 2.01e-01 | 8.60e-02 | 2.72e+00 | 6.58e-03 | 1.16e-02 | 1.15e-01 |
Top |
Exon skipping events with PSI in TCGA for PTGER4 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
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| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for PTGER4 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for PTGER4 |
| TFs related to PTGER4. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| SKCM | NR4A2 | PTGER4 | 4.43e+00 | 1.48e-02 | 5.28e+00 | 9.81e-01 | Female-biased |
| SKCM | SOX4 | PTGER4 | 3.89e+00 | 7.99e-03 | 4.94e+00 | 9.85e-01 | Female-biased |
| SKCM | ZNF570 | PTGER4 | 3.43e+00 | 3.13e-03 | 4.78e+00 | 9.88e-01 | Female-biased |
| UVM | ZNF570 | PTGER4 | 2.61e+00 | 2.92e-03 | 4.49e+00 | 9.82e-01 | Female-biased |
| PTGER4 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for PTGER4 |
| RBPs related to ES in PTGER4. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| PTGER4 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs11958525 | chr5:30793626:T:G | - | 0.303659863769588 | 0.00317455224049073 | GBM | Female-baised eQTL |
| rs56080361 | chr5:41163473:T:C | - | 0.221683117935275 | 0.0137083181313028 | GBM | Female-baised eQTL |
| rs73753103 | chr5:41165082:T:A | - | 0.221683117935275 | 0.0137083181313028 | GBM | Female-baised eQTL |
| rs6889037 | chr5:41220521:G:C | - | 0.215107543596165 | 0.0233000608001136 | GBM | Female-baised eQTL |
| rs10076584 | chr5:41222684:G:T | - | 0.215107543596165 | 0.0233000608001136 | GBM | Female-baised eQTL |
| rs9763132 | chr5:41225286:C:A | - | 0.215107543596165 | 0.0233000608001136 | GBM | Female-baised eQTL |
| rs55902512 | chr5:35202168:C:T | - | 0.181449733342959 | 0.0290372781405348 | GBM | Female-baised eQTL |
| rs72734580 | chr5:35204821:A:T | - | 0.181449733342959 | 0.0290372781405348 | GBM | Female-baised eQTL |
| rs7737481 | chr5:37782301:A:G | - | 0.22317099807805 | 0.0401076864038059 | GBM | Female-baised eQTL |
| rs11960031 | chr5:36171235:C:A | - | 0.197108292226297 | 0.043594720170829 | GBM | Female-baised eQTL |
| rs497982 | chr5:43132281:A:G | - | 0.232460780515724 | 0.0367608457346835 | BLCA | Female-baised eQTL |
| rs524985 | chr5:43133560:A:G | - | 0.232460780515724 | 0.0367608457346835 | BLCA | Female-baised eQTL |
| rs612532 | chr5:31395072:G:A | - | -0.0685799647215294 | 0.0417849946923338 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs903845 | chr5:34533376:A:G | - | 0.13432154296901 | 0.0214462046397886 | GBM | Male-baised eQTL |
| rs13361114 | chr5:34534430:T:C | - | 0.13432154296901 | 0.0214462046397886 | GBM | Male-baised eQTL |
| rs7725566 | chr5:34535479:A:C | - | 0.13432154296901 | 0.0214462046397886 | GBM | Male-baised eQTL |
| rs28491996 | chr5:34536556:C:G | - | 0.12975329471406 | 0.0302356980203414 | GBM | Male-baised eQTL |
| rs6897100 | chr5:34536970:G:C | - | 0.12975329471406 | 0.0302356980203414 | GBM | Male-baised eQTL |
| rs60521644 | chr5:39824110:A:C | - | 0.102353899857979 | 0.042746199384593 | GBM | Male-baised eQTL |
| rs10053689 | chr5:39824627:T:C | - | 0.102353899857979 | 0.042746199384593 | GBM | Male-baised eQTL |
| rs6895329 | chr5:39825638:T:C | - | 0.102353899857979 | 0.042746199384593 | GBM | Male-baised eQTL |
| rs10064798 | chr5:39826356:A:T | - | 0.102353899857979 | 0.042746199384593 | GBM | Male-baised eQTL |
| rs1389450 | chr5:39826581:T:G | - | 0.102353899857979 | 0.042746199384593 | GBM | Male-baised eQTL |
| rs36108557 | chr5:50475256:C:T | - | 0.0908342513498333 | 0.00813491039276463 | BLCA | Male-baised eQTL |
| rs34634456 | chr5:50153534:G:A | - | 0.0843730020518901 | 0.0128681657885265 | BLCA | Male-baised eQTL |
| rs141406561 | chr5:50154297:G:A | - | 0.0843730020518901 | 0.0128681657885265 | BLCA | Male-baised eQTL |
| rs375896736 | chr5:50154696:G:A | - | 0.0843730020518901 | 0.0128681657885265 | BLCA | Male-baised eQTL |
| rs138364687 | chr5:50160505:C:T | - | 0.0843730020518901 | 0.0128681657885265 | BLCA | Male-baised eQTL |
| rs34596501 | chr5:50166448:A:G | - | 0.0843730020518901 | 0.0128681657885265 | BLCA | Male-baised eQTL |
| rs137952180 | chr5:50171215:G:A | - | 0.0843730020518901 | 0.0128681657885265 | BLCA | Male-baised eQTL |
| rs113047096 | chr5:50173675:C:T | - | 0.0843730020518901 | 0.0128681657885265 | BLCA | Male-baised eQTL |
| rs35620350 | chr5:50173929:G:A | - | 0.0843730020518901 | 0.0128681657885265 | BLCA | Male-baised eQTL |
| rs34601010 | chr5:50179496:G:T | - | 0.0843730020518901 | 0.0128681657885265 | BLCA | Male-baised eQTL |
| rs35948942 | chr5:50202639:C:T | - | 0.0843730020518901 | 0.0128681657885265 | BLCA | Male-baised eQTL |
| rs13177150 | chr5:50206919:G:A | - | 0.0843730020518901 | 0.0128681657885265 | BLCA | Male-baised eQTL |
| rs34549889 | chr5:50208052:G:A | - | 0.0843730020518901 | 0.0128681657885265 | BLCA | Male-baised eQTL |
| rs113242756 | chr5:50214465:C:T | - | 0.0843730020518901 | 0.0128681657885265 | BLCA | Male-baised eQTL |
| rs115526328 | chr5:50216598:C:T | - | 0.0843730020518901 | 0.0128681657885265 | BLCA | Male-baised eQTL |
| rs375204450 | chr5:50217562:T:A | - | 0.0843730020518901 | 0.0128681657885265 | BLCA | Male-baised eQTL |
| rs34199557 | chr5:50220919:G:A | - | 0.0843730020518901 | 0.0128681657885265 | BLCA | Male-baised eQTL |
| rs34972141 | chr5:50221917:C:T | - | 0.0843730020518901 | 0.0128681657885265 | BLCA | Male-baised eQTL |
| rs115939391 | chr5:50222654:A:T | - | 0.0843730020518901 | 0.0128681657885265 | BLCA | Male-baised eQTL |
| rs138359496 | chr5:50222656:G:A | - | 0.0843730020518901 | 0.0128681657885265 | BLCA | Male-baised eQTL |
| rs35781657 | chr5:50225311:G:A | - | 0.0843730020518901 | 0.0128681657885265 | BLCA | Male-baised eQTL |
| rs71631441 | chr5:50230359:C:G | - | 0.0843730020518901 | 0.0128681657885265 | BLCA | Male-baised eQTL |
| rs34765996 | chr5:50241405:C:T | - | 0.0829114578981547 | 0.0148406793624406 | BLCA | Male-baised eQTL |
| rs35453547 | chr5:50241663:G:C | - | 0.0829114578981547 | 0.0148406793624406 | BLCA | Male-baised eQTL |
| rs1831151 | chr5:50242792:G:C | - | 0.0829114578981547 | 0.0148406793624406 | BLCA | Male-baised eQTL |
| rs34932129 | chr5:50224832:C:T | - | 0.08180318459006 | 0.0177533637020401 | BLCA | Male-baised eQTL |
| rs35345124 | chr5:50161521:G:C | - | 0.0810132089172154 | 0.0186154585636038 | BLCA | Male-baised eQTL |
| rs36144253 | chr5:50149688:C:G | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs143870946 | chr5:50150473:T:G | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs13153474 | chr5:50151665:T:C | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs71623911 | chr5:50152005:A:C | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs34850873 | chr5:50156331:C:T | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs34482469 | chr5:50156597:G:A | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs13169082 | chr5:50157119:C:T | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs13170014 | chr5:50157724:G:A | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs141293789 | chr5:50159644:G:T | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs35278921 | chr5:50164093:G:A | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs147788379 | chr5:50171085:T:G | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs149290743 | chr5:50171413:T:C | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs74924253 | chr5:50172753:C:T | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs145536751 | chr5:50172936:G:T | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs13182703 | chr5:50177836:G:T | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs34427429 | chr5:50179472:C:T | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs13170606 | chr5:50181014:G:A | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs13177308 | chr5:50206966:G:A | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs375123620 | chr5:50207905:T:C | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs34937333 | chr5:50208187:T:C | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs71631431 | chr5:50210294:C:T | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs35333117 | chr5:50213959:G:A | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs4555872 | chr5:50214570:C:T | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs71631434 | chr5:50215190:C:A | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs35296135 | chr5:50219734:C:A | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs36172500 | chr5:50223939:T:C | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs13156366 | chr5:50227303:C:A | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs7293370 | chr5:50229347:G:A | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs61541847 | chr5:50229958:C:T | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs7293350 | chr5:50234102:G:A | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs13182254 | chr5:50234964:T:A | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs13177211 | chr5:50239716:C:G | - | 0.0800238419768992 | 0.0214673287753867 | BLCA | Male-baised eQTL |
| rs60416360 | chr5:50241306:A:G | - | 0.0786732260428826 | 0.0243764228680723 | BLCA | Male-baised eQTL |
| rs35797623 | chr5:50241763:C:T | - | 0.0786732260428826 | 0.0243764228680723 | BLCA | Male-baised eQTL |
| rs35659543 | chr5:50241969:A:G | - | 0.0786732260428826 | 0.0243764228680723 | BLCA | Male-baised eQTL |
| rs71621979 | chr5:46401383:G:A | - | 0.0843235242329337 | 0.0281498146697455 | BLCA | Male-baised eQTL |
| rs34696334 | chr5:46297830:A:G | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs13166839 | chr5:46298508:A:G | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs34043196 | chr5:46299907:C:T | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs78120259 | chr5:46303820:T:A | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs78744747 | chr5:46305121:G:T | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs77201990 | chr5:46305143:A:T | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs13177011 | chr5:46307465:C:A | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs34171995 | chr5:46308876:G:A | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs35354757 | chr5:46310761:T:G | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs74705554 | chr5:46310974:G:T | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs36168382 | chr5:46313585:G:A | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs114562515 | chr5:46314177:C:T | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs71620167 | chr5:46317629:C:T | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs368485844 | chr5:46323223:A:G | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs35905321 | chr5:46325669:T:A | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs4975987 | chr5:46327025:C:G | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs145723412 | chr5:46330708:T:C | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs36167896 | chr5:46335668:C:G | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs8185013 | chr5:46336261:G:T | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs369368974 | chr5:46337110:A:G | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs77100380 | chr5:46343088:A:T | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs35521855 | chr5:46344608:C:T | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs35002629 | chr5:46344939:C:T | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs35358364 | chr5:46345778:T:C | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs143164066 | chr5:46374041:A:T | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs71620200 | chr5:46374700:A:T | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs71621960 | chr5:46374718:A:G | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs140905717 | chr5:46375608:G:A | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs147052664 | chr5:46375684:G:C | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs35176426 | chr5:46377697:A:T | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs71621965 | chr5:46379774:C:T | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs114349048 | chr5:46382001:A:C | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs116415445 | chr5:46382174:C:T | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs13184551 | chr5:46384388:C:A | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs71621972 | chr5:46385041:C:A | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs146941445 | chr5:46385357:G:T | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs36014970 | chr5:46385856:G:A | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs34097293 | chr5:46386166:C:T | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs114420471 | chr5:46390311:T:A | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs35279969 | chr5:46391124:A:G | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs35414899 | chr5:46391417:C:A | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs34832661 | chr5:46392219:G:C | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs71621977 | chr5:46399259:A:G | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs71621978 | chr5:46399495:A:G | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs13157926 | chr5:46400417:T:C | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs71621980 | chr5:46401425:G:A | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs36090405 | chr5:46402637:G:A | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs35931781 | chr5:46403201:T:C | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs76835095 | chr5:46404965:G:A | - | 0.080627349531682 | 0.0413192877978415 | BLCA | Male-baised eQTL |
| rs13152933 | chr5:46314952:C:G | - | 0.0803059724640843 | 0.0430848289456557 | BLCA | Male-baised eQTL |
| rs143165622 | chr5:46314004:G:A | - | 0.0802464840358123 | 0.0436089184278394 | BLCA | Male-baised eQTL |
| rs71620180 | chr5:46333967:C:T | - | 0.0800980145801989 | 0.0443876764712623 | BLCA | Male-baised eQTL |
| rs34537665 | chr5:46345003:G:A | - | 0.0800641111619291 | 0.0445816295346705 | BLCA | Male-baised eQTL |
| rs199666982 | chr5:46387369:T:A | - | 0.0803465552216744 | 0.0461224060634367 | BLCA | Male-baised eQTL |
| rs79206774 | chr5:46343087:A:T | - | 0.0787241913176673 | 0.0487993563744784 | BLCA | Male-baised eQTL |
| rs7735138 | chr5:37239138:A:C | - | 0.0426232810430204 | 0.0182967622617807 | LUAD | Male-baised eQTL |
| rs16903365 | chr5:36835306:G:A | - | 0.0652898480563886 | 0.0455381163692318 | LUAD | Male-baised eQTL |
| rs16903466 | chr5:37040436:A:G | - | 0.068925353704156 | 0.0484054789195704 | LUAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000171522 |
| CpG Site: cg11821200 | |
| Position to Gene: gene | |
| Male Effect: -0.274663849405063 | |
| Female Effect: - | |
 | Gene ID: ENSG00000171522 |
| CpG Site: cg01091117 | |
| Position to Gene: gene,enhancer | |
| Male Effect: - | |
| Female Effect: -0.353955781806004 | |
 | Gene ID: ENSG00000171522 |
| CpG Site: cg01091117 | |
| Position to Gene: gene,enhancer | |
| Male Effect: - | |
| Female Effect: -0.364891325658561 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg11821200 | chr5:40685887 | gene | -0.274663849405063 | 6.15458483459411e-09 | -0.6880237058434489 | 1.7764585921434213e-12 | LAML |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg01091117 | chr5:40682231 | gene,enhancer | -0.353955781806004 | 2.24634586859378e-14 | -0.4161114851422033 | 7.663704328958719e-17 | THCA |
| cg01091117 | chr5:40682231 | gene,enhancer | -0.364891325658561 | 3.64388391831167e-10 | -0.42297151951869805 | 1.7255065747778035e-12 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of PTGER4 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000171522 | PTGER4 | C0003865 | Arthritis, Adjuvant-Induced | 1 | CTD_human |
| ENSG00000171522 | PTGER4 | C0010093 | Corpus Luteum Cyst | 1 | CTD_human |
| ENSG00000171522 | PTGER4 | C0014175 | Endometriosis | 1 | CTD_human |
| ENSG00000171522 | PTGER4 | C0021368 | Inflammation | 1 | CTD_human |
| ENSG00000171522 | PTGER4 | C0024299 | Lymphoma | 1 | CTD_human |
| ENSG00000171522 | PTGER4 | C0029927 | Ovarian Cysts | 1 | CTD_human |
| ENSG00000171522 | PTGER4 | C0038013 | Ankylosing spondylitis | 1 | CTD_human |
| ENSG00000171522 | PTGER4 | C0237873 | Physiological Sexual Disorders | 1 | CTD_human |
| ENSG00000171522 | PTGER4 | C0263454 | Chloracne | 1 | CTD_human |
| ENSG00000171522 | PTGER4 | C0269102 | Endometrioma | 1 | CTD_human |
| ENSG00000171522 | PTGER4 | C0971858 | Arthritis, Collagen-Induced | 1 | CTD_human |
| ENSG00000171522 | PTGER4 | C0993582 | Arthritis, Experimental | 1 | CTD_human |
