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Gene: ENSG00000170745 |
Summary for KCNS3 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000170745 | Gene symbol | KCNS3 |
| Gene name | potassium voltage-gated channel modifier subfamily S member 3 | |
| HGNC | 6302 | |
| Entrez ID | 3790 | |
| Gene type | protein_coding | |
| Synonyms | KCNS3|Kv9.3 | |
| UniProtAcc | Q9BQ31 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for KCNS3 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| KCNS3 | 3.30e+02 | -1.29e+00 | 2.59e-01 | -4.97e+00 | 6.62e-07 | 2.56e-06 | COAD |
| KCNS3 | 1.28e+03 | 2.14e+00 | 5.14e-01 | 4.17e+00 | 3.08e-05 | 3.85e-04 | ESCA |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| KCNS3 | 8.81e+02 | 1.45e+00 | 4.75e-01 | 3.06e+00 | 2.20e-03 | 1.54e-02 | BLCA |
| KCNS3 | 2.05e+03 | 1.06e+00 | 1.09e-01 | 9.73e+00 | 2.20e-22 | 8.20e-22 | BRCA |
Top |
Sex-biased somatic mutation for KCNS3 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for KCNS3 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| READ | cg14482308 | chr2:17877842 | CGI:chr2:17877771-17877978 | promoter | 4.48e-01 | 3.37e-01 | 2.37e+00 | 1.77e-02 | 3.40e-02 | 1.11e-01 |
| READ | cg27365825 | chr2:17877863 | CGI:chr2:17877771-17877978 | UTR,promoter,exon,gene body | 4.61e-01 | 3.59e-01 | 2.02e+00 | 4.32e-02 | 4.78e-02 | 1.01e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg19024632 | chr2:17877836 | CGI:chr2:17877771-17877978 | promoter | 3.91e-01 | 2.83e-01 | 3.65e+00 | 2.67e-04 | 4.85e-04 | 1.09e-01 |
| LIHC | cg23986335 | chr2:17878189 | CGI:chr2:17878226-17879653 | promoter,gene body | 2.92e-01 | 1.53e-01 | 2.11e+00 | 3.48e-02 | 3.64e-02 | 1.39e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg14482308 | chr2:17877842 | CGI:chr2:17877771-17877978 | promoter | 3.06e-01 | 1.29e-01 | 5.01e+00 | 5.39e-07 | 1.03e-06 | 1.77e-01 |
| BRCA | cg11999255 | chr2:17877450 | CGI:chr2:17877771-17877978 | promoter | 4.15e-01 | 2.98e-01 | 6.79e+00 | 1.15e-11 | 3.24e-11 | 1.16e-01 |
| BRCA | cg19024632 | chr2:17877836 | CGI:chr2:17877771-17877978 | promoter | 3.62e-01 | 2.44e-01 | 5.41e+00 | 6.44e-08 | 1.34e-07 | 1.18e-01 |
| BRCA | cg27365825 | chr2:17877863 | CGI:chr2:17877771-17877978 | UTR,promoter,exon,gene body | 3.02e-01 | 1.49e-01 | 4.50e+00 | 6.95e-06 | 1.18e-05 | 1.53e-01 |
| HNSC | cg09282497 | chr2:17877933 | CGI:chr2:17877771-17877978 | UTR,promoter,exon,gene body | 1.23e-01 | 1.57e-02 | 2.76e+00 | 5.78e-03 | 1.42e-02 | 1.07e-01 |
| HNSC | cg19024632 | chr2:17877836 | CGI:chr2:17877771-17877978 | promoter | 3.91e-01 | 2.56e-01 | 2.07e+00 | 3.85e-02 | 4.17e-02 | 1.35e-01 |
| HNSC | cg27365825 | chr2:17877863 | CGI:chr2:17877771-17877978 | UTR,promoter,exon,gene body | 3.77e-01 | 1.71e-01 | 2.02e+00 | 4.29e-02 | 4.48e-02 | 2.06e-01 |
| COAD | cg01555853 | chr2:17878477 | CGI:chr2:17878226-17879653 | promoter,gene body | 1.90e-01 | 7.60e-02 | 2.69e+00 | 7.25e-03 | 1.25e-02 | 1.14e-01 |
| LIHC | cg19024632 | chr2:17877836 | CGI:chr2:17877771-17877978 | promoter | 4.93e-01 | 3.77e-01 | 2.73e+00 | 6.35e-03 | 9.71e-03 | 1.16e-01 |
Top |
Exon skipping events with PSI in TCGA for KCNS3 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
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| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for KCNS3 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for KCNS3 |
| TFs related to KCNS3. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
 |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| CHOL | ZNF580 | KCNS3 | 3.01e+00 | 6.94e-03 | 4.02e+00 | 9.81e-01 | Female-biased |
| KCNS3 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for KCNS3 |
| RBPs related to ES in KCNS3. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| KCNS3 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs1560276 | chr2:16264668:T:G | - | 0.174281295611831 | 0.0427130747142272 | PCPG | Female-baised eQTL |
| rs967502 | chr2:20078895:C:G | - | 0.18369634580042 | 0.0448340546619746 | PCPG | Female-baised eQTL |
| rs2635618 | chr2:18479775:C:G | - | 0.309364514694205 | 0.0204421255245985 | GBM | Female-baised eQTL |
| rs514805 | chr2:9870946:T:C | - | 0.0928050466570617 | 0.0458936114947854 | SARC | Female-baised eQTL |
| rs388570 | chr2:9871843:C:T | - | 0.0928050466570617 | 0.0458936114947854 | SARC | Female-baised eQTL |
| rs7583442 | chr2:20156845:G:T | - | 0.263968591005751 | 0.0212132769047081 | KIRP | Female-baised eQTL |
| rs79469798 | chr2:20157291:G:A | - | 0.263968591005751 | 0.0212132769047081 | KIRP | Female-baised eQTL |
| rs4666296 | chr2:20152299:T:C | - | 0.262712651038635 | 0.023451128421354 | KIRP | Female-baised eQTL |
| rs13429604 | chr2:23151765:T:C | - | 0.149154295697187 | 0.0250238037369664 | LIHC | Female-baised eQTL |
| rs4665201 | chr2:23155996:G:A | - | 0.139728151852174 | 0.0461177669123006 | LIHC | Female-baised eQTL |
| rs56822967 | chr2:23156166:C:T | - | 0.139728151852174 | 0.0461177669123006 | LIHC | Female-baised eQTL |
| rs66642611 | chr2:23154838:G:C | - | 0.139229652237478 | 0.0485152487712077 | LIHC | Female-baised eQTL |
| rs12619955 | chr2:14955152:C:T | - | 0.141447867945249 | 0.0312581790564519 | COAD | Female-baised eQTL |
| rs1996540 | chr2:14936077:G:A | - | 0.126298669605055 | 0.0402857822376646 | COAD | Female-baised eQTL |
| rs11888257 | chr2:16989772:A:C | - | 0.0919667057649091 | 0.0488821278830918 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs17045574 | chr2:23572050:C:A | - | 0.0677238954194534 | 0.000304582320728835 | HNSC | Male-baised eQTL |
| rs4665224 | chr2:23551801:A:G | - | 0.0572720856746317 | 0.00106717932515846 | HNSC | Male-baised eQTL |
| rs4665221 | chr2:23549461:T:C | - | 0.0620754265359944 | 0.00175960622024043 | HNSC | Male-baised eQTL |
| rs12473746 | chr2:23563288:C:T | - | 0.0596581747545974 | 0.00226556112111138 | HNSC | Male-baised eQTL |
| rs2018457 | chr2:23560512:G:A | - | 0.0582791687405292 | 0.00338433531122045 | HNSC | Male-baised eQTL |
| rs2018271 | chr2:23560334:G:T | - | 0.0578874269051345 | 0.00340886343172777 | HNSC | Male-baised eQTL |
| rs4665223 | chr2:23551720:T:G | - | 0.0564359166975113 | 0.00511290060056585 | HNSC | Male-baised eQTL |
| rs1010828 | chr2:23558025:C:T | - | 0.0538996478369749 | 0.0078277502949679 | HNSC | Male-baised eQTL |
| rs4665612 | chr2:23558348:C:T | - | 0.0538996478369749 | 0.0078277502949679 | HNSC | Male-baised eQTL |
| rs17045548 | chr2:23557597:G:A | - | 0.0537795472682607 | 0.00916157641623961 | HNSC | Male-baised eQTL |
| rs1010827 | chr2:23558178:G:C | - | 0.0537795472682607 | 0.00916157641623961 | HNSC | Male-baised eQTL |
| rs10179169 | chr2:23550392:G:A | - | 0.0542859714533395 | 0.0135003587793092 | HNSC | Male-baised eQTL |
| rs13386329 | chr2:22307865:C:T | - | 0.0498519869442128 | 0.0243513904430617 | HNSC | Male-baised eQTL |
| rs372378359 | chr2:16263823:A:G | - | 0.191253181721889 | 0.0118452618681568 | SARC | Male-baised eQTL |
| rs12474041 | chr2:19974133:G:A | - | 0.0455923323230235 | 0.0127543024481774 | LIHC | Male-baised eQTL |
| rs62109422 | chr2:19991671:T:C | - | 0.0452251440800941 | 0.0139420915213681 | LIHC | Male-baised eQTL |
| rs3731661 | chr2:19911095:G:A | - | 0.044289793263732 | 0.0173390408968399 | LIHC | Male-baised eQTL |
| rs7587014 | chr2:19919769:C:A | - | 0.044289793263732 | 0.0173390408968399 | LIHC | Male-baised eQTL |
| rs148368177 | chr2:19920928:C:T | - | 0.044289793263732 | 0.0173390408968399 | LIHC | Male-baised eQTL |
| rs77026681 | chr2:19924838:A:G | - | 0.044289793263732 | 0.0173390408968399 | LIHC | Male-baised eQTL |
| rs62109407 | chr2:19928319:T:A | - | 0.044289793263732 | 0.0173390408968399 | LIHC | Male-baised eQTL |
| rs62109409 | chr2:19928585:T:A | - | 0.044289793263732 | 0.0173390408968399 | LIHC | Male-baised eQTL |
| rs62109410 | chr2:19942031:T:C | - | 0.044289793263732 | 0.0173390408968399 | LIHC | Male-baised eQTL |
| rs736952 | chr2:19944210:G:C | - | 0.044289793263732 | 0.0173390408968399 | LIHC | Male-baised eQTL |
| rs62109414 | chr2:19954279:A:T | - | 0.044289793263732 | 0.0173390408968399 | LIHC | Male-baised eQTL |
| rs12479284 | chr2:19955525:C:T | - | 0.044289793263732 | 0.0173390408968399 | LIHC | Male-baised eQTL |
| rs3731667 | chr2:20005436:C:A | - | 0.0414666653965393 | 0.023581004770581 | LIHC | Male-baised eQTL |
| rs6734005 | chr2:20001697:G:A | - | 0.0408253249533637 | 0.0318498785369672 | LIHC | Male-baised eQTL |
| rs10206736 | chr2:16569851:C:T | - | 0.0585101838949767 | 0.0437035548457873 | LGG | Male-baised eQTL |
| rs72776607 | chr2:15177440:C:A | - | 0.0490424012718593 | 0.0462283148087207 | LGG | Male-baised eQTL |
| rs6545699 | chr2:24738072:T:G | - | 0.0822851576486832 | 0.0363434766091835 | BLCA | Male-baised eQTL |
| rs6739575 | chr2:24739269:A:G | - | 0.0822851576486832 | 0.0363434766091835 | BLCA | Male-baised eQTL |
| rs1439963 | chr2:24726143:G:A | - | 0.0807295834651191 | 0.0376102692902946 | BLCA | Male-baised eQTL |
| rs3928467 | chr2:24748990:T:G | - | 0.0822357500697653 | 0.038303802653649 | BLCA | Male-baised eQTL |
| rs11125763 | chr2:24752076:T:G | - | 0.0822357500697653 | 0.038303802653649 | BLCA | Male-baised eQTL |
| rs12713393 | chr2:24787097:A:G | - | 0.0821063463367423 | 0.0383877366455625 | BLCA | Male-baised eQTL |
| rs7568310 | chr2:24519477:G:A | - | 0.0820550293394539 | 0.0396053878389877 | BLCA | Male-baised eQTL |
| rs7568317 | chr2:24519486:G:T | - | 0.0820550293394539 | 0.0396053878389877 | BLCA | Male-baised eQTL |
| rs7586018 | chr2:24542617:T:C | - | 0.0815788098541974 | 0.0418327732506906 | BLCA | Male-baised eQTL |
| rs13011653 | chr2:24548375:T:C | - | 0.0815788098541974 | 0.0418327732506906 | BLCA | Male-baised eQTL |
| rs4635488 | chr2:24553444:G:C | - | 0.0815788098541974 | 0.0418327732506906 | BLCA | Male-baised eQTL |
| rs995647 | chr2:24587386:G:A | - | 0.0815788098541974 | 0.0418327732506906 | BLCA | Male-baised eQTL |
| rs7593430 | chr2:24710820:A:C | - | 0.0813705314005955 | 0.0426156301916777 | BLCA | Male-baised eQTL |
| rs6759752 | chr2:24764336:T:C | - | 0.0802506861563422 | 0.04525268915574 | BLCA | Male-baised eQTL |
| rs6707070 | chr2:24765928:T:C | - | 0.0802506861563422 | 0.04525268915574 | BLCA | Male-baised eQTL |
| rs4665266 | chr2:24514343:A:T | - | 0.0809507276535814 | 0.04639256660286 | BLCA | Male-baised eQTL |
| rs11125765 | chr2:24756595:C:T | - | 0.079686060318535 | 0.0466374653178279 | BLCA | Male-baised eQTL |
| rs1400030 | chr2:14415282:T:C | - | 0.0724734785478245 | 0.0163202609091339 | LUAD | Male-baised eQTL |
| rs4668827 | chr2:14415450:C:T | - | 0.0724734785478245 | 0.0163202609091339 | LUAD | Male-baised eQTL |
| rs34753169 | chr2:14416781:A:G | - | 0.0724734785478245 | 0.0163202609091339 | LUAD | Male-baised eQTL |
| rs16861722 | chr2:14419143:T:C | - | 0.0724734785478245 | 0.0163202609091339 | LUAD | Male-baised eQTL |
| rs13014275 | chr2:14420012:C:T | - | 0.0724734785478245 | 0.0163202609091339 | LUAD | Male-baised eQTL |
| rs1904655 | chr2:14421674:G:T | - | 0.0723248379276389 | 0.0169047174441322 | LUAD | Male-baised eQTL |
| rs1904656 | chr2:14421713:T:C | - | 0.0723248379276389 | 0.0169047174441322 | LUAD | Male-baised eQTL |
| rs1904657 | chr2:14421821:C:T | - | 0.0723248379276389 | 0.0169047174441322 | LUAD | Male-baised eQTL |
| rs4490157 | chr2:14422005:G:A | - | 0.0723248379276389 | 0.0169047174441322 | LUAD | Male-baised eQTL |
| rs4467250 | chr2:14422216:G:A | - | 0.0723248379276389 | 0.0169047174441322 | LUAD | Male-baised eQTL |
| rs13034976 | chr2:14422937:C:T | - | 0.0723248379276389 | 0.0169047174441322 | LUAD | Male-baised eQTL |
| rs61116613 | chr2:14424000:C:T | - | 0.0723248379276389 | 0.0169047174441322 | LUAD | Male-baised eQTL |
| rs1515941 | chr2:14425529:A:G | - | 0.0723248379276389 | 0.0169047174441322 | LUAD | Male-baised eQTL |
| rs13426290 | chr2:14427329:T:C | - | 0.068792554719204 | 0.0193622665580022 | LUAD | Male-baised eQTL |
| rs62131648 | chr2:14422054:T:C | - | 0.0683687574428829 | 0.0195324915364783 | LUAD | Male-baised eQTL |
| rs13012229 | chr2:14423535:A:C | - | 0.0683687574428829 | 0.0195324915364783 | LUAD | Male-baised eQTL |
| rs10209607 | chr2:26326604:A:G | - | 0.139579646150333 | 0.0019303605333524 | COAD | Male-baised eQTL |
| rs7584933 | chr2:26398343:C:T | - | 0.129075275410881 | 0.007391644959093 | COAD | Male-baised eQTL |
| rs7592979 | chr2:26353414:G:T | - | 0.117752227364083 | 0.00922976733634949 | COAD | Male-baised eQTL |
| rs55866113 | chr2:26379494:G:A | - | 0.126892684057798 | 0.0110524906280624 | COAD | Male-baised eQTL |
| rs4993056 | chr2:26383597:G:A | - | 0.126892684057798 | 0.0110524906280624 | COAD | Male-baised eQTL |
| rs7355249 | chr2:26361322:C:T | - | 0.114156921062535 | 0.0118991392805651 | COAD | Male-baised eQTL |
| rs1864459 | chr2:26401029:A:T | - | 0.117555976277614 | 0.0151980315098885 | COAD | Male-baised eQTL |
| rs10207722 | chr2:26321010:A:G | - | 0.0807059587307308 | 0.0347957085701268 | COAD | Male-baised eQTL |
| rs10196811 | chr2:21471115:G:A | - | 0.124040560436015 | 0.0372356212895342 | COAD | Male-baised eQTL |
| rs115633320 | chr2:21474842:T:C | - | 0.124040560436015 | 0.0372356212895342 | COAD | Male-baised eQTL |
| rs148722255 | chr2:21475076:A:G | - | 0.124040560436015 | 0.0372356212895342 | COAD | Male-baised eQTL |
| rs113602496 | chr2:21476309:C:G | - | 0.124040560436015 | 0.0372356212895342 | COAD | Male-baised eQTL |
| rs59559571 | chr2:21476351:G:C | - | 0.124040560436015 | 0.0372356212895342 | COAD | Male-baised eQTL |
| rs2081409 | chr2:21476917:G:A | - | 0.124040560436015 | 0.0372356212895342 | COAD | Male-baised eQTL |
| rs2098826 | chr2:21477261:G:T | - | 0.124040560436015 | 0.0372356212895342 | COAD | Male-baised eQTL |
| rs2081411 | chr2:21477401:T:G | - | 0.124040560436015 | 0.0372356212895342 | COAD | Male-baised eQTL |
| rs16985408 | chr2:18666090:C:G | - | 0.0721334141206872 | 0.0374769069725987 | COAD | Male-baised eQTL |
| rs11693798 | chr2:14396880:C:T | - | 0.0675101024343987 | 0.0396262601748193 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000170745 |
| CpG Site: cg25104233 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.347924064980978 | |
 | Gene ID: ENSG00000170745 |
| CpG Site: cg10265016 | |
| Position to Gene: gene,enhancer | |
| Male Effect: -0.100572611598615 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg10265016 | chr2:17880052 | gene,enhancer | -0.100572611598615 | 7.46621263404666e-10 | -0.35689825523004093 | 1.7019748017497132e-12 | HNSC |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg25104233 | chr2:17977442 | gene | -0.347924064980978 | 5.95160951352068e-05 | -0.3910513753339217 | 1.2590127288436924e-06 | SARC |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of KCNS3 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000170745 | KCNS3 | C0036341 | Schizophrenia | 1 | PSYGENET |
