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Gene: ENSG00000170681 |
Summary for MURC |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000170681 | Gene symbol | MURC |
| Gene name | caveolae associated protein 4 | |
| HGNC | 33742 | |
| Entrez ID | 347273 | |
| Gene type | protein_coding | |
| Synonyms | CAVIN4|cavin-4 | |
| UniProtAcc | Q5BKX8 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
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Structure and expression level for MURC |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
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| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| MURC | 5.42e+02 | -2.68e+00 | 4.34e-01 | -6.17e+00 | 6.84e-10 | 4.11e-09 | HNSC |
| Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
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Sex-biased somatic mutation for MURC |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for MURC |
| Landscape of DNA methylation across multiple cancer types. |
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| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUAD | cg14429381 | chr9:100579817 | CGI:chr9:100598673-100599030 | promoter,gene body | 8.17e-01 | 7.10e-01 | 4.24e+00 | 2.21e-05 | 8.03e-05 | 1.06e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BLCA | cg14429381 | chr9:100579817 | CGI:chr9:100598673-100599030 | promoter,gene body | 7.35e-01 | 8.47e-01 | -2.18e+00 | 2.92e-02 | 3.48e-02 | -1.12e-01 |
| LIHC | cg14429381 | chr9:100579817 | CGI:chr9:100598673-100599030 | promoter,gene body | 7.88e-01 | 9.01e-01 | -2.71e+00 | 6.73e-03 | 1.02e-02 | -1.12e-01 |
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Exon skipping events with PSI in TCGA for MURC |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
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RNA A-to-I editing events in TCGA for MURC |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for MURC |
| TFs related to MURC. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| CHOL | FOXC2 | MURC | 7.60e+00 | 9.83e-01 | 6.75e+00 | 1.69e-02 | Male-biased |
| CHOL | ZNF418 | MURC | 8.09e+00 | 9.96e-01 | 6.89e+00 | 4.25e-03 | Male-biased |
| CHOL | ZNF879 | MURC | 7.65e+00 | 9.94e-01 | 6.53e+00 | 5.94e-03 | Male-biased |
| DLBC | ZNF418 | MURC | 4.72e+00 | 6.55e-03 | 5.74e+00 | 9.92e-01 | Female-biased |
| DLBC | ZNF879 | MURC | 4.61e+00 | 8.91e-03 | 5.54e+00 | 9.90e-01 | Female-biased |
| SARC | ZNF418 | MURC | 7.11e+00 | 9.90e-01 | 6.54e+00 | 9.93e-03 | Male-biased |
| SARC | ZNF879 | MURC | 6.74e+00 | 9.89e-01 | 6.19e+00 | 1.08e-02 | Male-biased |
| MURC related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for MURC |
| RBPs related to ES in MURC. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| MURC related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs148971106 | chr9:102150565:T:G | - | 0.125923247742773 | 0.00122157891981978 | SARC | Female-baised eQTL |
| rs10820068 | chr9:102121399:C:T | - | 0.121028419975942 | 0.00201503011060334 | SARC | Female-baised eQTL |
| rs1597340 | chr9:102155251:G:T | - | 0.12043950691994 | 0.00228349710748644 | SARC | Female-baised eQTL |
| rs10760830 | chr9:102029773:A:G | - | 0.111624353168765 | 0.00599984133780464 | SARC | Female-baised eQTL |
| rs10760831 | chr9:102035048:T:C | - | 0.111624353168765 | 0.00599984133780464 | SARC | Female-baised eQTL |
| rs2417317 | chr9:102047293:C:A | - | 0.107727315088841 | 0.0065606143064323 | SARC | Female-baised eQTL |
| rs10820031 | chr9:102022441:T:C | - | 0.110993639823067 | 0.00660289189607023 | SARC | Female-baised eQTL |
| rs10820032 | chr9:102022580:G:A | - | 0.110993639823067 | 0.00660289189607023 | SARC | Female-baised eQTL |
| rs10820036 | chr9:102033194:C:T | - | 0.107450916343864 | 0.00892065224600726 | SARC | Female-baised eQTL |
| rs10820037 | chr9:102033314:G:A | - | 0.107450916343864 | 0.00892065224600726 | SARC | Female-baised eQTL |
| rs3918975 | chr9:102030608:A:T | - | 0.10513671496606 | 0.0104923000711042 | SARC | Female-baised eQTL |
| rs10989773 | chr9:102019286:A:G | - | 0.094945043973917 | 0.027170856170804 | SARC | Female-baised eQTL |
| rs10820039 | chr9:102042790:G:A | - | 0.0909360791664953 | 0.0348020982155623 | SARC | Female-baised eQTL |
| rs10820055 | chr9:102095671:C:T | - | 0.0899007147408203 | 0.0413602266647264 | SARC | Female-baised eQTL |
| rs895989 | chr9:102096423:C:T | - | 0.0899007147408203 | 0.0413602266647264 | SARC | Female-baised eQTL |
| rs10989820 | chr9:102099670:C:T | - | 0.0899007147408203 | 0.0413602266647264 | SARC | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of MURC |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
