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Gene: ENSG00000169783 |
Summary for LINGO1 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000169783 | Gene symbol | LINGO1 |
| Gene name | leucine rich repeat and Ig domain containing 1 | |
| HGNC | 21205 | |
| Entrez ID | 84894 | |
| Gene type | protein_coding | |
| Synonyms | LINGO1|FLJ14594|LERN1 | |
| UniProtAcc | Q96FE5 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for LINGO1 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| LINGO1 | 3.82e+02 | -1.40e+00 | 1.89e-01 | -7.45e+00 | 9.41e-14 | 2.10e-11 | LIHC |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| LINGO1 | 2.61e+02 | 1.11e+00 | 4.54e-01 | 2.44e+00 | 1.49e-02 | 3.34e-02 | BLCA |
| LINGO1 | 5.15e+02 | 1.96e+00 | 4.98e-01 | 3.94e+00 | 8.29e-05 | 8.64e-04 | ESCA |
| LINGO1 | 8.35e+02 | 3.42e+00 | 7.28e-01 | 4.69e+00 | 2.67e-06 | 1.75e-05 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
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| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| LINGO1 | 2.11e+02 | 1.25e+00 | 3.24e-01 | 3.87e+00 | 1.11e-04 | 2.78e-04 | COAD |
| LINGO1 | 1.37e+03 | 2.48e+00 | 1.54e-01 | 1.61e+01 | 3.77e-58 | 4.83e-57 | BRCA |
| LINGO1 | 1.99e+02 | 1.07e+00 | 4.60e-01 | 2.33e+00 | 1.97e-02 | 4.37e-02 | READ |
Top |
Sex-biased somatic mutation for LINGO1 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for LINGO1 |
| Landscape of DNA methylation across multiple cancer types. |
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| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg09369863 | chr15:77820505 | CGI:chr15:77818499-77820511 | promoter,gene body | 5.91e-02 | 2.11e-01 | -2.07e+00 | 3.86e-02 | 4.53e-02 | -1.52e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUAD | cg24240466 | chr15:77819488 | CGI:chr15:77818499-77820511 | promoter,exon,gene body | 1.36e-01 | 2.55e-02 | 3.14e+00 | 1.67e-03 | 2.99e-03 | 1.11e-01 |
| LUSC | cg16602846 | chr15:77821936 | CGI:chr15:77818499-77820511 | promoter | 3.27e-01 | 4.48e-01 | -4.10e+00 | 4.09e-05 | 5.36e-04 | -1.21e-01 |
| BLCA | cg16602846 | chr15:77821936 | CGI:chr15:77818499-77820511 | promoter | 2.75e-01 | 4.03e-01 | -4.48e+00 | 7.47e-06 | 8.37e-05 | -1.28e-01 |
| LIHC | cg13981360 | chr15:77820895 | CGI:chr15:77818499-77820511 | UTR,promoter,exon,gene body | 2.62e-01 | 3.75e-01 | -4.21e+00 | 2.60e-05 | 6.30e-05 | -1.13e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUAD | cg13981360 | chr15:77820895 | CGI:chr15:77818499-77820511 | UTR,promoter,exon,gene body | 2.74e-01 | 3.80e-01 | -2.42e+00 | 1.56e-02 | 2.17e-02 | -1.06e-01 |
Top |
Exon skipping events with PSI in TCGA for LINGO1 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for LINGO1 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for LINGO1 |
| TFs related to LINGO1. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| LINGO1 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for LINGO1 |
| RBPs related to ES in LINGO1. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| LINGO1 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs147047918 | chr15:76722482:C:G | - | 0.137042382882806 | 0.0191520246077393 | PAAD | Female-baised eQTL |
| rs8030521 | chr15:76604871:T:G | - | -0.127065279702381 | 0.041096143259311 | PAAD | Female-baised eQTL |
| rs12442966 | chr15:76625949:G:T | - | -0.127065279702381 | 0.041096143259311 | PAAD | Female-baised eQTL |
| rs1443110 | chr15:76635981:C:T | - | -0.127065279702381 | 0.041096143259311 | PAAD | Female-baised eQTL |
| rs2468129 | chr15:76550871:T:G | - | 0.127065279702381 | 0.041096143259311 | PAAD | Female-baised eQTL |
| rs2439992 | chr15:76570682:T:G | - | 0.127065279702381 | 0.041096143259311 | PAAD | Female-baised eQTL |
| rs2468116 | chr15:76578657:G:A | - | 0.127065279702381 | 0.041096143259311 | PAAD | Female-baised eQTL |
| rs2439984 | chr15:76631576:T:C | - | 0.127065279702381 | 0.041096143259311 | PAAD | Female-baised eQTL |
| rs2439982 | chr15:76632730:T:G | - | 0.127065279702381 | 0.041096143259311 | PAAD | Female-baised eQTL |
| rs2468123 | chr15:76639004:T:C | - | 0.127065279702381 | 0.041096143259311 | PAAD | Female-baised eQTL |
| rs279997 | chr15:76656921:T:C | - | 0.127065279702381 | 0.041096143259311 | PAAD | Female-baised eQTL |
| rs61066917 | chr15:85863456:G:A | - | 0.158204114938063 | 0.0295375064763572 | LIHC | Female-baised eQTL |
| rs8032095 | chr15:85863621:A:G | - | 0.158204114938063 | 0.0295375064763572 | LIHC | Female-baised eQTL |
| rs8032211 | chr15:85863647:A:G | - | 0.158204114938063 | 0.0295375064763572 | LIHC | Female-baised eQTL |
| rs8032224 | chr15:85863673:A:G | - | 0.158204114938063 | 0.0295375064763572 | LIHC | Female-baised eQTL |
| rs8031852 | chr15:85863838:C:G | - | 0.158204114938063 | 0.0295375064763572 | LIHC | Female-baised eQTL |
| rs73445847 | chr15:85864070:C:A | - | 0.158204114938063 | 0.0295375064763572 | LIHC | Female-baised eQTL |
| rs73445849 | chr15:85864270:C:A | - | 0.158204114938063 | 0.0295375064763572 | LIHC | Female-baised eQTL |
| rs61606084 | chr15:85864369:G:A | - | 0.158204114938063 | 0.0295375064763572 | LIHC | Female-baised eQTL |
| rs57010492 | chr15:85864506:G:A | - | 0.158204114938063 | 0.0295375064763572 | LIHC | Female-baised eQTL |
| rs56091151 | chr15:85864647:C:T | - | 0.158204114938063 | 0.0295375064763572 | LIHC | Female-baised eQTL |
| rs75442358 | chr15:70060371:T:C | - | 0.186213352284197 | 0.0308187913802299 | LIHC | Female-baised eQTL |
| rs16945347 | chr15:85859947:G:A | - | 0.159591254974898 | 0.033470686821623 | LIHC | Female-baised eQTL |
| rs4843124 | chr15:85861461:G:A | - | 0.159591254974898 | 0.033470686821623 | LIHC | Female-baised eQTL |
| rs73445838 | chr15:85860532:G:A | - | 0.156009441313726 | 0.0352672275833321 | LIHC | Female-baised eQTL |
| rs4843123 | chr15:85860925:G:A | - | 0.156009441313726 | 0.0352672275833321 | LIHC | Female-baised eQTL |
| rs4842904 | chr15:85861103:C:A | - | 0.156009441313726 | 0.0352672275833321 | LIHC | Female-baised eQTL |
| rs10152888 | chr15:85861724:C:G | - | 0.156009441313726 | 0.0352672275833321 | LIHC | Female-baised eQTL |
| rs2344861 | chr15:85862358:C:T | - | 0.156009441313726 | 0.0352672275833321 | LIHC | Female-baised eQTL |
| rs1986595 | chr15:85862473:A:G | - | 0.156009441313726 | 0.0352672275833321 | LIHC | Female-baised eQTL |
| rs8024866 | chr15:85862845:G:A | - | 0.156009441313726 | 0.0352672275833321 | LIHC | Female-baised eQTL |
| rs16945393 | chr15:85863050:G:A | - | 0.156009441313726 | 0.0352672275833321 | LIHC | Female-baised eQTL |
| rs78212770 | chr15:70079438:C:G | - | 0.18588135755074 | 0.0404668430576401 | LIHC | Female-baised eQTL |
| rs1878884 | chr15:70066592:C:T | - | -0.178324923097679 | 0.0417973218404079 | LIHC | Female-baised eQTL |
| rs76962864 | chr15:70052032:C:T | - | 0.189664326858053 | 0.0418263927343477 | LIHC | Female-baised eQTL |
| rs2291981 | chr15:70058268:C:T | - | 0.189664326858053 | 0.0418263927343477 | LIHC | Female-baised eQTL |
| rs3809508 | chr15:84655660:T:C | - | -0.136117447391763 | 0.00806274203885641 | LUSC | Female-baised eQTL |
| rs4280214 | chr15:84673033:A:G | - | -0.11483580076368 | 0.0358323981260983 | LUSC | Female-baised eQTL |
| rs150962 | chr15:84543080:A:C | - | -0.155718125018673 | 0.0385610495263962 | LUSC | Female-baised eQTL |
| rs6603018 | chr15:84052267:A:G | - | -0.154031650824182 | 0.0468489904945201 | LUSC | Female-baised eQTL |
| rs4531707 | chr15:86673927:A:C | - | -0.0919526885231519 | 0.0445152758460817 | COAD | Female-baised eQTL |
| rs6496352 | chr15:86677895:A:G | - | -0.0897526620620667 | 0.0465176836617923 | COAD | Female-baised eQTL |
| rs8028043 | chr15:86674382:A:G | - | -0.0899352850781154 | 0.0496886858231703 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs12595358 | chr15:86194071:A:G | - | 0.101749356292386 | 0.0475363303188625 | READ | Male-baised eQTL |
| rs114765259 | chr15:81587048:T:G | - | 0.157004290404275 | 0.00212048498210117 | PAAD | Male-baised eQTL |
| rs111633114 | chr15:81586751:A:G | - | 0.156900804846737 | 0.00221124255455616 | PAAD | Male-baised eQTL |
| rs16973033 | chr15:81596949:A:C | - | 0.146591665016954 | 0.0046815230889525 | PAAD | Male-baised eQTL |
| rs149062560 | chr15:81584065:C:T | - | 0.217210632965789 | 0.0230747450337073 | THCA | Male-baised eQTL |
| rs17337944 | chr15:75138185:C:T | - | 0.173715009651027 | 0.0252482554487526 | THCA | Male-baised eQTL |
| rs72754306 | chr15:69051517:G:C | - | 0.104792485989954 | 0.00244185716833184 | LUSC | Male-baised eQTL |
| rs8024894 | chr15:69055925:T:C | - | 0.104792485989954 | 0.00244185716833184 | LUSC | Male-baised eQTL |
| rs167483 | chr15:69065354:G:A | - | -0.0913375223410171 | 0.00916946119441455 | LUSC | Male-baised eQTL |
| rs311928 | chr15:69048354:G:A | - | -0.0886765209472614 | 0.0129656913521613 | LUSC | Male-baised eQTL |
| rs2958398 | chr15:68893232:A:G | - | -0.0794799324772016 | 0.0246958107644647 | LUSC | Male-baised eQTL |
| rs2958399 | chr15:68893340:T:C | - | -0.0794799324772016 | 0.0246958107644647 | LUSC | Male-baised eQTL |
| rs3922599 | chr15:68896870:T:C | - | 0.0727836021249599 | 0.0445998847731443 | LUSC | Male-baised eQTL |
| rs76878931 | chr15:78616556:G:A | - | 0.0827972485152027 | 0.0169604011789478 | STAD | Male-baised eQTL |
| rs202126010 | chr15:78612057:A:G | - | 0.0808661625726965 | 0.018875315121286 | STAD | Male-baised eQTL |
| rs146898316 | chr15:78612619:G:A | - | 0.0808661625726965 | 0.018875315121286 | STAD | Male-baised eQTL |
| rs76695999 | chr15:78622952:C:G | - | 0.0781133912279695 | 0.0245111385258882 | STAD | Male-baised eQTL |
| rs79802316 | chr15:78625793:A:C | - | 0.0781133912279695 | 0.0245111385258882 | STAD | Male-baised eQTL |
| rs78090107 | chr15:78606999:G:A | - | 0.0778142212977982 | 0.0258769288281633 | STAD | Male-baised eQTL |
| rs79596927 | chr15:78607484:A:G | - | 0.0778142212977982 | 0.0258769288281633 | STAD | Male-baised eQTL |
| rs138183042 | chr15:78607712:A:C | - | 0.0778142212977982 | 0.0258769288281633 | STAD | Male-baised eQTL |
| rs74947410 | chr15:78620789:G:A | - | 0.0751915796581203 | 0.0333237205640599 | STAD | Male-baised eQTL |
| rs80103354 | chr15:78616209:C:T | - | 0.0762421903091051 | 0.0346492056171056 | STAD | Male-baised eQTL |
| rs3743076 | chr15:78616885:T:A | - | 0.0735246754677667 | 0.0376576837975849 | STAD | Male-baised eQTL |
| rs79053468 | chr15:78616464:C:A | - | 0.0734273634786145 | 0.0383905709453024 | STAD | Male-baised eQTL |
| rs28723505 | chr15:68376239:C:T | - | -0.0620010298715188 | 0.0489047199507952 | KIRC | Male-baised eQTL |
| rs11072015 | chr15:68376270:C:T | - | -0.0620010298715188 | 0.0489047199507952 | KIRC | Male-baised eQTL |
| rs75927241 | chr15:72684326:T:C | - | 0.0906982507977748 | 0.00435076027488172 | LUAD | Male-baised eQTL |
| rs77225745 | chr15:72691835:C:T | - | 0.0906982507977748 | 0.00435076027488172 | LUAD | Male-baised eQTL |
| rs79460572 | chr15:72693846:T:C | - | 0.0920905219740238 | 0.00467166930008468 | LUAD | Male-baised eQTL |
| rs77296598 | chr15:72702719:T:A | - | 0.0918836235411013 | 0.00478795244362646 | LUAD | Male-baised eQTL |
| rs17753768 | chr15:72703628:C:T | - | 0.0918836235411013 | 0.00478795244362646 | LUAD | Male-baised eQTL |
| rs76576336 | chr15:72699939:A:G | - | 0.087453456396178 | 0.00706044024146083 | LUAD | Male-baised eQTL |
| rs72755940 | chr15:82958900:G:C | - | 0.0945215061374776 | 0.031237618698164 | LUAD | Male-baised eQTL |
| rs80311077 | chr15:83168862:T:C | - | 0.0923234302966819 | 0.0458291998943249 | LUAD | Male-baised eQTL |
| rs7167676 | chr15:73787680:T:G | - | 0.0757546116237127 | 0.0461003499352961 | LUAD | Male-baised eQTL |
| rs72758319 | chr15:83188682:C:T | - | 0.0921290272237114 | 0.0469131155522352 | LUAD | Male-baised eQTL |
| rs1948497 | chr15:83399014:C:T | - | 0.0759638968822163 | 0.0472865922019659 | LUAD | Male-baised eQTL |
| rs4887300 | chr15:87563125:C:A | - | 0.0679127533833167 | 0.00279366948661583 | COAD | Male-baised eQTL |
| rs11633752 | chr15:87528900:C:A | - | 0.0691591161908318 | 0.00297043477217491 | COAD | Male-baised eQTL |
| rs12898349 | chr15:87559260:G:A | - | 0.0661232905831898 | 0.00369842377683726 | COAD | Male-baised eQTL |
| rs12437766 | chr15:87559586:A:C | - | 0.0661232905831898 | 0.00369842377683726 | COAD | Male-baised eQTL |
| rs12437767 | chr15:87559588:A:T | - | 0.0661232905831898 | 0.00369842377683726 | COAD | Male-baised eQTL |
| rs8026588 | chr15:87556358:G:A | - | 0.0657774989439191 | 0.00387106256509518 | COAD | Male-baised eQTL |
| rs8032943 | chr15:87556359:T:A | - | 0.0657774989439191 | 0.00387106256509518 | COAD | Male-baised eQTL |
| rs12904811 | chr15:87560940:G:C | - | 0.0654932275278144 | 0.00404552450370631 | COAD | Male-baised eQTL |
| rs12906123 | chr15:87560943:C:T | - | 0.0654932275278144 | 0.00404552450370631 | COAD | Male-baised eQTL |
| rs4146308 | chr15:87564008:G:A | - | 0.0633446174082891 | 0.00521205014331888 | COAD | Male-baised eQTL |
| rs4887301 | chr15:87564103:G:A | - | 0.0621080257136659 | 0.00720832486777951 | COAD | Male-baised eQTL |
| rs4887299 | chr15:87555898:C:G | - | 0.0609222857252183 | 0.00878323355999506 | COAD | Male-baised eQTL |
| rs11637283 | chr15:85772872:C:T | - | 0.0582537858181498 | 0.0124414075861708 | COAD | Male-baised eQTL |
| rs4887188 | chr15:87562941:G:A | - | 0.0550855152133839 | 0.016507833719146 | COAD | Male-baised eQTL |
| rs56183577 | chr15:85776475:A:G | - | 0.0561306522718804 | 0.0191100598294107 | COAD | Male-baised eQTL |
| rs11631009 | chr15:85775422:G:A | - | 0.0559750185346364 | 0.0194910502232552 | COAD | Male-baised eQTL |
| rs12916187 | chr15:85782893:A:C | - | 0.0560330551288753 | 0.0199921314698998 | COAD | Male-baised eQTL |
| rs11073721 | chr15:87564501:G:C | - | 0.0535480367748119 | 0.0210998719929695 | COAD | Male-baised eQTL |
| rs12900830 | chr15:85782923:T:C | - | 0.055198468067432 | 0.0231395339322018 | COAD | Male-baised eQTL |
| rs2127648 | chr15:82900017:C:T | - | 0.0874613833641082 | 0.0319697316686809 | COAD | Male-baised eQTL |
| rs11633790 | chr15:85783139:G:A | - | 0.0520484728245563 | 0.0350514385923036 | COAD | Male-baised eQTL |
| rs74633828 | chr15:85421688:G:A | - | 0.077412464276615 | 0.0368318178875752 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000169783 |
| CpG Site: cg14070108 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.491219954091438 | |
 | Gene ID: ENSG00000169783 |
| CpG Site: cg27398640 | |
| Position to Gene: gene | |
| Male Effect: - | |
| Female Effect: -0.491068489654175 | |
 | Gene ID: ENSG00000169783 |
| CpG Site: cg26919657 | |
| Position to Gene: gene | |
| Male Effect: -0.440322167152699 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg26919657 | chr15:77712338 | gene | -0.440322167152699 | 5.85327546082503e-14 | -0.5238405286257806 | 6.65830890166412e-17 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg14070108 | chr15:77629821 | gene | -0.491219954091438 | 1.67650565386151e-68 | -0.9932459884448624 | 9.843627764358506e-75 | PAAD |
| cg27398640 | chr15:77618264 | gene | -0.491068489654175 | 3.09943800220358e-67 | -0.9933703895353775 | 3.2071970242451983e-72 | PAAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of LINGO1 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000169783 | LINGO1 | C0270736 | Essential Tremor | 1 | CTD_human |
| ENSG00000169783 | LINGO1 | C0393615 | Familial Tremor | 1 | CTD_human |
