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Gene: ENSG00000165617 |
Summary for DACT1 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000165617 | Gene symbol | DACT1 |
| Gene name | dishevelled binding antagonist of beta catenin 1 | |
| HGNC | 17748 | |
| Entrez ID | 51339 | |
| Gene type | protein_coding | |
| Synonyms | DACT1|DAPPER1|THYEX3|HDPR1|DAPPER|FRODO | |
| UniProtAcc | Q9NYF0 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for DACT1 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| DACT1 | 6.76e+02 | -1.27e+00 | 2.43e-01 | -5.21e+00 | 1.90e-07 | 1.28e-06 | THCA |
| DACT1 | 4.34e+02 | -1.50e+00 | 5.06e-01 | -2.96e+00 | 3.10e-03 | 8.79e-03 | BLCA |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| DACT1 | 3.89e+02 | 1.07e+00 | 4.24e-01 | 2.52e+00 | 1.16e-02 | 3.26e-02 | HNSC |
| DACT1 | 3.33e+02 | -1.18e+00 | 3.87e-01 | -3.05e+00 | 2.27e-03 | 9.90e-03 | KIRP |
Top |
Sex-biased somatic mutation for DACT1 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for DACT1 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| GBM | cg13503816 | chr14:58635555 | CGI:chr14:58637581-58638859 | promoter,gene body | 6.23e-01 | 7.24e-01 | 4.06e+00 | 5.00e-05 | 2.63e-04 | -1.00e-01 |
| KICH | cg13503816 | chr14:58635555 | CGI:chr14:58637581-58638859 | promoter,gene body | 2.23e-01 | 5.38e-01 | 2.83e+00 | 4.72e-03 | 1.74e-02 | -3.15e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRP | cg13503816 | chr14:58635555 | CGI:chr14:58637581-58638859 | promoter,gene body | 7.66e-01 | 5.00e-01 | 2.04e+00 | 4.17e-02 | 4.29e-02 | 2.66e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| HNSC | cg23033518 | chr14:58635001 | CGI:chr14:58637581-58638859 | promoter,gene body | 2.24e-01 | 1.22e-01 | 2.49e+00 | 1.28e-02 | 2.13e-02 | 1.02e-01 |
Top |
Exon skipping events with PSI in TCGA for DACT1 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for DACT1 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for DACT1 |
| TFs related to DACT1. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| DACT1 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for DACT1 |
| RBPs related to ES in DACT1. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| DACT1 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000165617 | AC110597.1,hsa-mir-32,DACT1 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000165617 | LINC01915,hsa-mir-32,DACT1 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000165617 | LINC01550,hsa-mir-32,DACT1 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000165617 | MEG8,hsa-mir-32,DACT1 | Male-specific ceRNA | TCGA-BLCA |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs17100173 | chr14:62655117:G:A | - | 0.164880187077038 | 0.0328335668806381 | HNSC | Female-baised eQTL |
| rs79874756 | chr14:62655461:G:A | - | 0.162460431044963 | 0.0401996291302449 | HNSC | Female-baised eQTL |
| rs77290861 | chr14:54535604:T:C | - | 0.231043422998411 | 0.000306002666736372 | GBM | Female-baised eQTL |
| rs58230752 | chr14:54536911:G:C | - | 0.231043422998411 | 0.000306002666736372 | GBM | Female-baised eQTL |
| rs112345096 | chr14:54547199:G:T | - | 0.231043422998411 | 0.000306002666736372 | GBM | Female-baised eQTL |
| rs75767084 | chr14:54549242:T:A | - | 0.231043422998411 | 0.000306002666736372 | GBM | Female-baised eQTL |
| rs17128156 | chr14:55086502:G:A | - | 0.251813253950589 | 0.00112954277778237 | GBM | Female-baised eQTL |
| rs111368121 | chr14:54515120:C:T | - | 0.180327172432407 | 0.00515023155968991 | GBM | Female-baised eQTL |
| rs7142742 | chr14:54494485:T:G | - | 0.213221927434251 | 0.00802487065201448 | GBM | Female-baised eQTL |
| rs17128008 | chr14:54841492:C:G | - | 0.163846107796894 | 0.0108681380831016 | GBM | Female-baised eQTL |
| rs7493025 | chr14:54845261:T:C | - | 0.163846107796894 | 0.0108681380831016 | GBM | Female-baised eQTL |
| rs74568258 | chr14:54539003:C:T | - | 0.206070871804007 | 0.015266511480313 | GBM | Female-baised eQTL |
| rs34355331 | chr14:61578695:T:C | - | 0.224736911593441 | 0.0164700843024426 | GBM | Female-baised eQTL |
| rs35392664 | chr14:61578544:G:A | - | 0.224349502974669 | 0.0165005737216699 | GBM | Female-baised eQTL |
| rs116861353 | chr14:54548605:G:A | - | 0.205366720894288 | 0.0166517244824655 | GBM | Female-baised eQTL |
| rs34310264 | chr14:61580606:A:G | - | 0.224125449885728 | 0.0170486864264741 | GBM | Female-baised eQTL |
| rs35251103 | chr14:61580845:G:A | - | 0.224125449885728 | 0.0170486864264741 | GBM | Female-baised eQTL |
| rs28691656 | chr14:61583334:A:G | - | 0.224125449885728 | 0.0170486864264741 | GBM | Female-baised eQTL |
| rs10143557 | chr14:61583872:C:G | - | 0.224125449885728 | 0.0170486864264741 | GBM | Female-baised eQTL |
| rs34839478 | chr14:61578765:T:C | - | 0.223310266812182 | 0.0182415187770468 | GBM | Female-baised eQTL |
| rs117251877 | chr14:66094144:G:A | - | 0.211011166691052 | 0.0204699953501483 | GBM | Female-baised eQTL |
| rs59165982 | chr14:58162404:T:C | - | 0.209313627104304 | 0.0228963829833453 | GBM | Female-baised eQTL |
| rs62005374 | chr14:58163864:C:T | - | 0.209313627104304 | 0.0228963829833453 | GBM | Female-baised eQTL |
| rs1956342 | chr14:58164137:C:T | - | 0.209313627104304 | 0.0228963829833453 | GBM | Female-baised eQTL |
| rs59516854 | chr14:58164847:T:C | - | 0.209313627104304 | 0.0228963829833453 | GBM | Female-baised eQTL |
| rs57726799 | chr14:58171992:C:T | - | 0.209313627104304 | 0.0228963829833453 | GBM | Female-baised eQTL |
| rs17094388 | chr14:58157961:T:C | - | 0.199164201148809 | 0.0253671582466933 | GBM | Female-baised eQTL |
| rs77379410 | chr14:56464753:A:C | - | 0.207746422492438 | 0.0265679198840517 | GBM | Female-baised eQTL |
| rs77818093 | chr14:56468424:C:T | - | 0.207746422492438 | 0.0265679198840517 | GBM | Female-baised eQTL |
| rs75661657 | chr14:56473514:C:T | - | 0.207746422492438 | 0.0265679198840517 | GBM | Female-baised eQTL |
| rs117993819 | chr14:56475682:A:C | - | 0.207746422492438 | 0.0265679198840517 | GBM | Female-baised eQTL |
| rs4898839 | chr14:54495014:G:A | - | 0.164804854642728 | 0.0412634322582783 | GBM | Female-baised eQTL |
| rs113793776 | chr14:54496744:G:A | - | 0.164804854642728 | 0.0412634322582783 | GBM | Female-baised eQTL |
| rs17127606 | chr14:54498226:T:C | - | 0.164804854642728 | 0.0412634322582783 | GBM | Female-baised eQTL |
| rs17127614 | chr14:54510477:T:A | - | 0.164804854642728 | 0.0412634322582783 | GBM | Female-baised eQTL |
| rs77371438 | chr14:54511082:A:G | - | 0.164804854642728 | 0.0412634322582783 | GBM | Female-baised eQTL |
| rs17127615 | chr14:54513474:G:A | - | 0.164804854642728 | 0.0412634322582783 | GBM | Female-baised eQTL |
| rs77764474 | chr14:54520733:G:A | - | 0.164804854642728 | 0.0412634322582783 | GBM | Female-baised eQTL |
| rs137992538 | chr14:54527382:A:G | - | 0.164804854642728 | 0.0412634322582783 | GBM | Female-baised eQTL |
| rs56899669 | chr14:54529504:A:C | - | 0.164804854642728 | 0.0412634322582783 | GBM | Female-baised eQTL |
| rs76481724 | chr14:54531952:G:A | - | 0.164804854642728 | 0.0412634322582783 | GBM | Female-baised eQTL |
| rs72720834 | chr14:62138246:T:C | - | 0.054383675349356 | 0.00560131331818081 | THCA | Female-baised eQTL |
| rs373998163 | chr14:51031908:C:G | - | 0.091107074474932 | 0.0474061530643064 | LUSC | Female-baised eQTL |
| rs8009082 | chr14:51032626:C:A | - | 0.091107074474932 | 0.0474061530643064 | LUSC | Female-baised eQTL |
| rs2132771 | chr14:52056685:T:G | - | -0.0672137739279991 | 0.0176142360792028 | KIRC | Female-baised eQTL |
| rs11851063 | chr14:52044470:C:T | - | 0.0716272887989464 | 0.0194276054805001 | KIRC | Female-baised eQTL |
| rs10141373 | chr14:52024581:C:T | - | 0.103878132908869 | 0.0214728572993279 | KIRC | Female-baised eQTL |
| rs730532 | chr14:52052093:G:A | - | -0.0661868323005366 | 0.0230750280923234 | KIRC | Female-baised eQTL |
| rs1390968 | chr14:52050911:A:G | - | -0.0661929751934705 | 0.0236639972370566 | KIRC | Female-baised eQTL |
| rs34900091 | chr14:52044991:T:C | - | 0.0700368564507731 | 0.0257470579448268 | KIRC | Female-baised eQTL |
| rs984050 | chr14:52068697:G:A | - | -0.0832206347804401 | 0.0259709062020431 | KIRC | Female-baised eQTL |
| rs3920038 | chr14:52068930:G:T | - | -0.0832206347804401 | 0.0259709062020431 | KIRC | Female-baised eQTL |
| rs8011845 | chr14:52072229:G:A | - | -0.0824851195734213 | 0.0278791480620211 | KIRC | Female-baised eQTL |
| rs8011522 | chr14:52072234:C:G | - | -0.0824851195734213 | 0.0278791480620211 | KIRC | Female-baised eQTL |
| rs4898730 | chr14:52076098:A:T | - | -0.0804371303678213 | 0.031035948484739 | KIRC | Female-baised eQTL |
| rs4898731 | chr14:52076100:G:T | - | -0.0804371303678213 | 0.031035948484739 | KIRC | Female-baised eQTL |
| rs4898732 | chr14:52076126:C:T | - | -0.0804371303678213 | 0.031035948484739 | KIRC | Female-baised eQTL |
| rs2029979 | chr14:52034693:C:T | - | -0.0915616489355283 | 0.03576896970846 | KIRC | Female-baised eQTL |
| rs11851036 | chr14:52044384:C:G | - | 0.0688474543519394 | 0.0406542968044941 | KIRC | Female-baised eQTL |
| rs6572813 | chr14:52072372:C:T | - | -0.0800868913701964 | 0.0432180725362675 | KIRC | Female-baised eQTL |
| rs10148284 | chr14:52026844:G:T | - | 0.0964355387333986 | 0.0454582646549573 | KIRC | Female-baised eQTL |
| rs28663441 | chr14:52027374:G:C | - | 0.0964355387333986 | 0.0454582646549573 | KIRC | Female-baised eQTL |
| rs34006905 | chr14:52028112:G:A | - | 0.0964355387333986 | 0.0454582646549573 | KIRC | Female-baised eQTL |
| rs67640320 | chr14:52044878:C:G | - | 0.0677836172582376 | 0.0461372215985752 | KIRC | Female-baised eQTL |
| rs28513068 | chr14:50010623:C:T | - | 0.130811988813774 | 0.000374148721238384 | LUAD | Female-baised eQTL |
| rs28495500 | chr14:50010742:A:G | - | 0.130811988813774 | 0.000374148721238384 | LUAD | Female-baised eQTL |
| rs28723038 | chr14:50010793:G:A | - | 0.130811988813774 | 0.000374148721238384 | LUAD | Female-baised eQTL |
| rs28481435 | chr14:50010845:C:G | - | 0.130811988813774 | 0.000374148721238384 | LUAD | Female-baised eQTL |
| rs28695275 | chr14:50010873:C:T | - | 0.130811988813774 | 0.000374148721238384 | LUAD | Female-baised eQTL |
| rs28376142 | chr14:49998862:A:C | - | 0.128763033419308 | 0.000418366652321338 | LUAD | Female-baised eQTL |
| rs28715274 | chr14:49998989:T:C | - | 0.133042843927332 | 0.000439449343561268 | LUAD | Female-baised eQTL |
| rs111374788 | chr14:50003668:A:G | - | 0.127476080398101 | 0.000521787041235181 | LUAD | Female-baised eQTL |
| rs111266019 | chr14:50009395:C:T | - | 0.1267928941984 | 0.000591981547266636 | LUAD | Female-baised eQTL |
| rs113985506 | chr14:50009679:T:A | - | 0.1267928941984 | 0.000591981547266636 | LUAD | Female-baised eQTL |
| rs113952878 | chr14:50009749:A:G | - | 0.1267928941984 | 0.000591981547266636 | LUAD | Female-baised eQTL |
| rs113134572 | chr14:50010193:C:T | - | 0.1267928941984 | 0.000591981547266636 | LUAD | Female-baised eQTL |
| rs140983503 | chr14:50010304:T:C | - | 0.1267928941984 | 0.000591981547266636 | LUAD | Female-baised eQTL |
| rs373360461 | chr14:50010311:G:A | - | 0.1267928941984 | 0.000591981547266636 | LUAD | Female-baised eQTL |
| rs75289624 | chr14:50010348:C:T | - | 0.1267928941984 | 0.000591981547266636 | LUAD | Female-baised eQTL |
| rs28679304 | chr14:50025376:T:C | - | 0.132827285650019 | 0.000602690318732674 | LUAD | Female-baised eQTL |
| rs10129492 | chr14:50012786:G:A | - | 0.126617255697919 | 0.000606641877924839 | LUAD | Female-baised eQTL |
| rs28613529 | chr14:50008189:C:G | - | 0.123431432461658 | 0.000850492241800119 | LUAD | Female-baised eQTL |
| rs28460429 | chr14:50016750:T:C | - | 0.121701394071787 | 0.000877586966045577 | LUAD | Female-baised eQTL |
| rs113038422 | chr14:50015948:G:C | - | 0.125239771889972 | 0.000956735678588766 | LUAD | Female-baised eQTL |
| rs112381251 | chr14:50018012:A:G | - | 0.124960540869019 | 0.00100631782892771 | LUAD | Female-baised eQTL |
| rs10141751 | chr14:50019507:G:T | - | 0.124960540869019 | 0.00100631782892771 | LUAD | Female-baised eQTL |
| rs74869159 | chr14:50009546:C:T | - | 0.101773634993791 | 0.00468068104450756 | LUAD | Female-baised eQTL |
| rs112152785 | chr14:50010065:T:C | - | 0.101410773358545 | 0.00499085954606622 | LUAD | Female-baised eQTL |
| rs10142191 | chr14:50020194:A:G | - | 0.0872546068683885 | 0.0318554936137179 | LUAD | Female-baised eQTL |
| rs10138297 | chr14:50018609:A:G | - | 0.0870899502294617 | 0.0326393536621052 | LUAD | Female-baised eQTL |
| rs10139402 | chr14:49999684:T:A | - | 0.0727680807385343 | 0.047434544951352 | LUAD | Female-baised eQTL |
| rs17095952 | chr14:59251958:G:A | - | 0.128434064096502 | 0.00165387815798503 | COAD | Female-baised eQTL |
| rs17095892 | chr14:59228331:A:G | - | 0.124791963483204 | 0.00207031747057131 | COAD | Female-baised eQTL |
| rs6573200 | chr14:58383177:G:A | - | -0.073972436361153 | 0.00790419478991758 | COAD | Female-baised eQTL |
| rs76155001 | chr14:59176483:A:G | - | 0.0985060857418389 | 0.0116299518230963 | COAD | Female-baised eQTL |
| rs75914025 | chr14:59177978:T:C | - | 0.0985060857418389 | 0.0116299518230963 | COAD | Female-baised eQTL |
| rs80323895 | chr14:59178934:T:G | - | 0.0985060857418389 | 0.0116299518230963 | COAD | Female-baised eQTL |
| rs77216482 | chr14:59181918:A:G | - | 0.0985060857418389 | 0.0116299518230963 | COAD | Female-baised eQTL |
| rs28712511 | chr14:59185925:T:C | - | 0.0985060857418389 | 0.0116299518230963 | COAD | Female-baised eQTL |
| rs115129197 | chr14:59182261:T:G | - | 0.0971869438535029 | 0.0261518281940484 | COAD | Female-baised eQTL |
| rs1438520 | chr14:59187092:A:T | - | 0.0971869438535029 | 0.0261518281940484 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs11850442 | chr14:66003631:A:G | - | 0.0705825199710418 | 0.0188560535025674 | LGG | Male-baised eQTL |
| rs7140911 | chr14:53678135:G:T | - | 0.0398091965916072 | 0.00513445278909195 | KIRC | Male-baised eQTL |
| rs17126757 | chr14:53679012:A:T | - | 0.0398091965916072 | 0.00513445278909195 | KIRC | Male-baised eQTL |
| rs7146962 | chr14:53678599:T:C | - | 0.0372244727904598 | 0.00850590356128263 | KIRC | Male-baised eQTL |
| rs112602253 | chr14:56071431:G:A | - | 0.0576991379281242 | 0.018692777088377 | KIRC | Male-baised eQTL |
| rs10130892 | chr14:62232707:T:A | - | -0.0296544214463003 | 0.0471003444512875 | KIRC | Male-baised eQTL |
| rs11846419 | chr14:57073766:A:C | - | 0.067846573070867 | 0.0483878788499544 | BLCA | Male-baised eQTL |
| rs35543418 | chr14:62421352:G:A | - | 0.092553177323239 | 0.000930080397298536 | COAD | Male-baised eQTL |
| rs11624067 | chr14:62419927:G:T | - | 0.0916048601595154 | 0.00104277170022103 | COAD | Male-baised eQTL |
| rs61987115 | chr14:68647748:T:G | - | 0.0981313183518558 | 0.00145319608542298 | COAD | Male-baised eQTL |
| rs11627397 | chr14:62418939:T:C | - | 0.0883346373066754 | 0.00213493700550767 | COAD | Male-baised eQTL |
| rs61987112 | chr14:68646001:C:T | - | 0.0966301892268538 | 0.00238450261131394 | COAD | Male-baised eQTL |
| rs7147493 | chr14:61932308:G:A | - | 0.113913601475702 | 0.00264186942202934 | COAD | Male-baised eQTL |
| rs2152484 | chr14:61980813:T:G | - | -0.141048140088902 | 0.00354796385077479 | COAD | Male-baised eQTL |
| rs72722793 | chr14:62373857:G:A | - | 0.0830118530330823 | 0.0040833915391707 | COAD | Male-baised eQTL |
| rs17251933 | chr14:48944788:T:C | - | 0.160970601260733 | 0.00487849880843022 | COAD | Male-baised eQTL |
| rs12323342 | chr14:59136812:A:G | - | 0.0832363035034425 | 0.0059808366805045 | COAD | Male-baised eQTL |
| rs12892161 | chr14:62383201:C:A | - | 0.0773035912113687 | 0.0103972072608087 | COAD | Male-baised eQTL |
| rs34030646 | chr14:62387615:C:A | - | 0.0767650581087872 | 0.0117302784244604 | COAD | Male-baised eQTL |
| rs35087713 | chr14:62675934:G:T | - | 0.0941818913478136 | 0.0191491173003323 | COAD | Male-baised eQTL |
| rs12883690 | chr14:62407637:T:C | - | 0.0751564983906935 | 0.0226468130293149 | COAD | Male-baised eQTL |
| rs35953497 | chr14:62411193:C:T | - | 0.0751564983906935 | 0.0226468130293149 | COAD | Male-baised eQTL |
| rs17810992 | chr14:62381088:C:A | - | 0.0693406846575184 | 0.026201189994103 | COAD | Male-baised eQTL |
| rs35804118 | chr14:54228887:G:A | - | 0.0586515367306606 | 0.0273674647967781 | COAD | Male-baised eQTL |
| rs10145635 | chr14:54229908:T:A | - | 0.0586515367306606 | 0.0273674647967781 | COAD | Male-baised eQTL |
| rs2186079 | chr14:62377444:A:T | - | 0.0689667209682716 | 0.028019906385587 | COAD | Male-baised eQTL |
| rs8007479 | chr14:68626920:T:A | - | 0.076079591246059 | 0.0301265308349254 | COAD | Male-baised eQTL |
| rs12882001 | chr14:50286158:T:C | - | 0.124462552326969 | 0.0303546198732974 | COAD | Male-baised eQTL |
| rs8011917 | chr14:68619217:G:A | - | 0.0789513560604668 | 0.0324967346916332 | COAD | Male-baised eQTL |
| rs7159652 | chr14:54223046:A:C | - | 0.0586168209393308 | 0.0328581518297842 | COAD | Male-baised eQTL |
| rs10149313 | chr14:62529193:G:A | - | 0.0790312720508224 | 0.033813066674385 | COAD | Male-baised eQTL |
| rs12892347 | chr14:62405997:G:A | - | 0.0711536518605584 | 0.0342349497395135 | COAD | Male-baised eQTL |
| rs61994780 | chr14:62666201:G:A | - | 0.0852637253060639 | 0.0349685819652235 | COAD | Male-baised eQTL |
| rs2355059 | chr14:62669225:C:T | - | 0.0852637253060639 | 0.0349685819652235 | COAD | Male-baised eQTL |
| rs78419480 | chr14:59199356:C:G | - | 0.110248287739361 | 0.0355249567921956 | COAD | Male-baised eQTL |
| rs7158757 | chr14:62416507:A:G | - | 0.0664048554854269 | 0.0357032617780294 | COAD | Male-baised eQTL |
| rs4638486 | chr14:54255922:A:C | - | 0.0572917943205447 | 0.0360119496956846 | COAD | Male-baised eQTL |
| rs112988802 | chr14:59523796:T:C | - | 0.129948030998297 | 0.0375662324147023 | COAD | Male-baised eQTL |
| rs17096257 | chr14:59477052:A:G | - | 0.129804097664792 | 0.038030964762095 | COAD | Male-baised eQTL |
| rs35560141 | chr14:62672289:A:G | - | 0.0827830829138891 | 0.0438990263005304 | COAD | Male-baised eQTL |
| rs113286608 | chr14:59111478:A:G | - | 0.0960063625006679 | 0.0451425972917003 | COAD | Male-baised eQTL |
| rs7400899 | chr14:54237955:A:G | - | 0.0555899836380762 | 0.0457424023936975 | COAD | Male-baised eQTL |
| rs4433730 | chr14:54250939:G:A | - | 0.0555899836380762 | 0.0457424023936975 | COAD | Male-baised eQTL |
| rs11629285 | chr14:54233277:C:T | - | 0.0554232579881988 | 0.0468602409086192 | COAD | Male-baised eQTL |
| rs147420922 | chr14:54235756:C:A | - | 0.0554232579881988 | 0.0468602409086192 | COAD | Male-baised eQTL |
| rs35400951 | chr14:62415427:G:T | - | 0.0658907074354446 | 0.0499122136282993 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000165617 |
| CpG Site: cg09250072 | |
| Position to Gene: gene | |
| Male Effect: -0.469036142634801 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg09250072 | chr14:58641019 | gene | -0.469036142634801 | 3.42112998445984e-30 | -0.7031340018399278 | 1.4163486216372e-34 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of DACT1 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000165617 | DACT1 | C0009402 | Colorectal Carcinoma | 1 | CTD_human |
| ENSG00000165617 | DACT1 | C0009404 | Colorectal Neoplasms | 1 | CTD_human |
| ENSG00000165617 | DACT1 | C0265246 | Townes syndrome | 1 | CTD_human |
