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Gene: ENSG00000163736 |
Summary for PPBP |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000163736 | Gene symbol | PPBP |
| Gene name | pro-platelet basic protein | |
| HGNC | 9240 | |
| Entrez ID | 5473 | |
| Gene type | protein_coding | |
| Synonyms | PPBP|SCYB7|TGB|NAP-2-L1|LA-PF4|MDGF|LDGF|Beta-TG|CTAP3|CXCL7|PBP|b-TG1|TGB1|CTAPIII|NAP-2 | |
| UniProtAcc | P02775 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| ENSG00000163736 | PPBP | DB03635 | Ethanesulfonic acid | SmallMoleculeDrug |
| ENSG00000163736 | PPBP | DB09130 | Copper | SmallMoleculeDrug |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for PPBP |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
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| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| PPBP | 5.00e+01 | -1.27e+00 | 2.32e-01 | -5.47e+00 | 4.45e-08 | 3.38e-06 | HNSC |
| PPBP | 1.84e+02 | 1.26e+00 | 2.43e-01 | 5.18e+00 | 2.22e-07 | 6.63e-05 | COAD |
| PPBP | 6.42e+01 | 1.50e+00 | 2.58e-01 | 5.81e+00 | 6.13e-09 | 1.63e-06 | STAD |
| PPBP | 1.08e+02 | 1.64e+00 | 3.63e-01 | 4.52e+00 | 6.05e-06 | 2.36e-03 | READ |
| Differentially expressed gene analysis between tumor male and normal male samples. |
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| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| PPBP | 7.52e+01 | 2.90e+00 | 5.60e-01 | 5.18e+00 | 2.19e-07 | 1.47e-06 | STAD |
| PPBP | 5.89e+01 | 3.76e+00 | 8.93e-01 | 4.21e+00 | 2.58e-05 | 3.32e-04 | ESCA |
| Differentially expressed gene analysis between tumor female and normal female samples. |
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| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| PPBP | 6.55e+01 | 2.23e+00 | 6.45e-01 | 3.46e+00 | 5.33e-04 | 2.46e-03 | HNSC |
| PPBP | 5.99e+01 | 4.17e+00 | 8.92e-01 | 4.67e+00 | 3.02e-06 | 2.28e-05 | READ |
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Sex-biased somatic mutation for PPBP |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for PPBP |
| Landscape of DNA methylation across multiple cancer types. |
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| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUSC | cg26523478 | chr4:73987616 | CGI:chr4:73981811-73982113 | promoter,exon,CDS,gene body | 8.31e-01 | 9.35e-01 | -2.80e+00 | 5.07e-03 | 8.24e-03 | -1.04e-01 |
| BLCA | cg26523478 | chr4:73987616 | CGI:chr4:73981811-73982113 | promoter,exon,CDS,gene body | 7.23e-01 | 9.26e-01 | -3.00e+00 | 2.69e-03 | 4.97e-03 | -2.03e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg26523478 | chr4:73987616 | CGI:chr4:73981811-73982113 | promoter,exon,CDS,gene body | 7.87e-01 | 9.32e-01 | -8.79e+00 | 1.46e-18 | 7.04e-18 | -1.45e-01 |
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Exon skipping events with PSI in TCGA for PPBP |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for PPBP |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for PPBP |
| TFs related to PPBP. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| MESO | FLI1 | PPBP | 3.22e+00 | 8.63e-03 | 4.54e+00 | 9.84e-01 | Female-biased |
| MESO | FOXB1 | PPBP | 5.78e+00 | 9.95e-01 | 4.25e+00 | 3.68e-03 | Male-biased |
| MESO | FOXQ1 | PPBP | 5.76e+00 | 9.90e-01 | 4.49e+00 | 8.69e-03 | Male-biased |
| MESO | HESX1 | PPBP | 6.41e+00 | 9.87e-01 | 5.27e+00 | 1.28e-02 | Male-biased |
| MESO | KLF15 | PPBP | 2.86e+00 | 2.72e-03 | 4.51e+00 | 9.90e-01 | Female-biased |
| MESO | LHX9 | PPBP | 6.44e+00 | 9.88e-01 | 5.27e+00 | 1.18e-02 | Male-biased |
| MESO | MAZ | PPBP | 2.96e+00 | 4.76e-03 | 4.45e+00 | 9.87e-01 | Female-biased |
| MESO | MYNN | PPBP | 5.32e+00 | 9.84e-01 | 4.21e+00 | 1.41e-02 | Male-biased |
| MESO | PRDM1 | PPBP | 5.10e+00 | 9.86e-01 | 3.93e+00 | 1.16e-02 | Male-biased |
| MESO | SPI1 | PPBP | 5.11e+00 | 9.85e-01 | 3.97e+00 | 1.26e-02 | Male-biased |
| MESO | SPIB | PPBP | 5.22e+00 | 9.84e-01 | 4.12e+00 | 1.42e-02 | Male-biased |
| MESO | VEZF1 | PPBP | 2.95e+00 | 5.06e-03 | 4.43e+00 | 9.87e-01 | Female-biased |
| MESO | ZNF132 | PPBP | 2.95e+00 | 1.33e-03 | 4.80e+00 | 9.94e-01 | Female-biased |
| MESO | ZNF263 | PPBP | 3.11e+00 | 6.15e-03 | 4.53e+00 | 9.87e-01 | Female-biased |
| MESO | ZNF398 | PPBP | 3.08e+00 | 3.37e-03 | 4.69e+00 | 9.91e-01 | Female-biased |
| MESO | ZNF432 | PPBP | 3.08e+00 | 5.20e-03 | 4.56e+00 | 9.88e-01 | Female-biased |
| MESO | ZNF467 | PPBP | 2.98e+00 | 3.68e-03 | 4.55e+00 | 9.90e-01 | Female-biased |
| MESO | ZNF605 | PPBP | 3.56e+00 | 2.55e-03 | 5.25e+00 | 9.95e-01 | Female-biased |
| MESO | ZNF667 | PPBP | 4.01e+00 | 1.67e-02 | 5.12e+00 | 9.80e-01 | Female-biased |
| MESO | ZNF765 | PPBP | 2.92e+00 | 8.03e-04 | 4.90e+00 | 9.95e-01 | Female-biased |
| MESO | ZNF768 | PPBP | 3.22e+00 | 2.45e-03 | 4.92e+00 | 9.94e-01 | Female-biased |
| MESO | ZNF774 | PPBP | 3.09e+00 | 1.04e-02 | 4.34e+00 | 9.80e-01 | Female-biased |
| MESO | ZNF880 | PPBP | 3.13e+00 | 4.49e-03 | 4.65e+00 | 9.90e-01 | Female-biased |
| PAAD | ZNF273 | PPBP | 5.05e+00 | 1.56e-02 | 5.76e+00 | 9.83e-01 | Female-biased |
| PAAD | ZNF69 | PPBP | 4.86e+00 | 1.67e-02 | 5.57e+00 | 9.82e-01 | Female-biased |
| SARC | FOXB1 | PPBP | 5.76e+00 | 9.93e-01 | 5.12e+00 | 6.33e-03 | Male-biased |
| SARC | FOXQ1 | PPBP | 5.66e+00 | 9.90e-01 | 5.08e+00 | 8.59e-03 | Male-biased |
| SARC | GBX1 | PPBP | 7.65e+00 | 9.87e-01 | 7.13e+00 | 1.31e-02 | Male-biased |
| SARC | HESX1 | PPBP | 6.33e+00 | 9.81e-01 | 5.86e+00 | 1.85e-02 | Male-biased |
| SARC | LHX9 | PPBP | 6.51e+00 | 9.85e-01 | 6.00e+00 | 1.42e-02 | Male-biased |
| SARC | MEIS1 | PPBP | 6.57e+00 | 9.95e-01 | 5.89e+00 | 4.71e-03 | Male-biased |
| SARC | MYNN | PPBP | 5.41e+00 | 9.91e-01 | 4.79e+00 | 7.27e-03 | Male-biased |
| SARC | PRDM1 | PPBP | 5.46e+00 | 9.94e-01 | 4.77e+00 | 4.57e-03 | Male-biased |
| SARC | ZNF398 | PPBP | 4.37e+00 | 9.84e-01 | 3.76e+00 | 7.07e-03 | Male-biased |
| THYM | ELF5 | PPBP | 4.67e+00 | 9.81e-01 | 4.05e+00 | 1.29e-02 | Male-biased |
| THYM | FOXB1 | PPBP | 4.52e+00 | 9.84e-01 | 3.81e+00 | 8.44e-03 | Male-biased |
| THYM | FOXQ1 | PPBP | 4.65e+00 | 9.83e-01 | 3.99e+00 | 1.08e-02 | Male-biased |
| THYM | LHX9 | PPBP | 5.58e+00 | 9.81e-01 | 5.02e+00 | 1.71e-02 | Male-biased |
| THYM | PRDM1 | PPBP | 4.52e+00 | 9.85e-01 | 3.77e+00 | 7.32e-03 | Male-biased |
| UVM | FLI1 | PPBP | 3.21e+00 | 3.97e-03 | 4.97e+00 | 9.89e-01 | Female-biased |
| UVM | FOXB1 | PPBP | 5.37e+00 | 9.94e-01 | 3.39e+00 | 2.39e-03 | Male-biased |
| UVM | FOXQ1 | PPBP | 5.53e+00 | 9.93e-01 | 3.75e+00 | 3.90e-03 | Male-biased |
| UVM | HESX1 | PPBP | 6.15e+00 | 9.92e-01 | 4.59e+00 | 6.37e-03 | Male-biased |
| UVM | KLF15 | PPBP | 3.09e+00 | 2.82e-03 | 5.00e+00 | 9.90e-01 | Female-biased |
| UVM | LHX9 | PPBP | 6.23e+00 | 9.92e-01 | 4.70e+00 | 6.92e-03 | Male-biased |
| UVM | MAZ | PPBP | 3.27e+00 | 7.37e-03 | 4.72e+00 | 9.82e-01 | Female-biased |
| UVM | MEIS1 | PPBP | 5.86e+00 | 9.83e-01 | 4.74e+00 | 1.53e-02 | Male-biased |
| UVM | MYNN | PPBP | 5.21e+00 | 9.92e-01 | 3.30e+00 | 2.89e-03 | Male-biased |
| UVM | PRDM1 | PPBP | 4.87e+00 | 9.81e-01 | 3.51e+00 | 9.16e-03 | Male-biased |
| UVM | VEZF1 | PPBP | 3.22e+00 | 5.89e-03 | 4.78e+00 | 9.84e-01 | Female-biased |
| UVM | ZNF132 | PPBP | 3.17e+00 | 8.50e-04 | 5.56e+00 | 9.97e-01 | Female-biased |
| UVM | ZNF225 | PPBP | 4.54e+00 | 9.85e-01 | 2.06e+00 | 6.41e-04 | Male-biased |
| UVM | ZNF235 | PPBP | 4.41e+00 | 9.82e-01 | 1.83e+00 | 4.90e-04 | Male-biased |
| UVM | ZNF263 | PPBP | 3.22e+00 | 4.81e-03 | 4.88e+00 | 9.87e-01 | Female-biased |
| UVM | ZNF398 | PPBP | 3.00e+00 | 1.33e-03 | 5.22e+00 | 9.94e-01 | Female-biased |
| UVM | ZNF432 | PPBP | 3.37e+00 | 6.67e-03 | 4.88e+00 | 9.85e-01 | Female-biased |
| UVM | ZNF467 | PPBP | 3.28e+00 | 5.35e-03 | 4.89e+00 | 9.86e-01 | Female-biased |
| UVM | ZNF605 | PPBP | 3.69e+00 | 7.22e-04 | 6.16e+00 | 9.98e-01 | Female-biased |
| UVM | ZNF667 | PPBP | 4.25e+00 | 9.13e-03 | 5.62e+00 | 9.88e-01 | Female-biased |
| UVM | ZNF69 | PPBP | 4.35e+00 | 1.09e-02 | 5.62e+00 | 9.87e-01 | Female-biased |
| UVM | ZNF765 | PPBP | 3.41e+00 | 4.86e-04 | 6.02e+00 | 9.98e-01 | Female-biased |
| UVM | ZNF768 | PPBP | 3.38e+00 | 1.55e-03 | 5.55e+00 | 9.96e-01 | Female-biased |
| UVM | ZNF880 | PPBP | 3.21e+00 | 3.17e-03 | 5.07e+00 | 9.91e-01 | Female-biased |
| PPBP related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for PPBP |
| RBPs related to ES in PPBP. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| PPBP related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs36071411 | chr4:64560329:T:C | - | 0.0406336376069552 | 0.0354352169490701 | LUAD | Female-baised eQTL |
| rs17086106 | chr4:65337769:C:G | - | 0.0892850808236671 | 0.000104876783630677 | COAD | Female-baised eQTL |
| rs67312120 | chr4:65338703:T:C | - | 0.0892918163161862 | 0.000105700151427617 | COAD | Female-baised eQTL |
| rs67668479 | chr4:65335031:T:C | - | 0.0860597377342584 | 0.000191337782215512 | COAD | Female-baised eQTL |
| rs35906413 | chr4:65355545:C:A | - | 0.0830849587365971 | 0.000317213524631108 | COAD | Female-baised eQTL |
| rs13124187 | chr4:65343193:A:C | - | 0.0830825498739767 | 0.000325372692794665 | COAD | Female-baised eQTL |
| rs34509814 | chr4:65323035:C:T | - | 0.0776241096992757 | 0.000772956671507806 | COAD | Female-baised eQTL |
| rs36037048 | chr4:65325027:G:A | - | 0.0776241096992757 | 0.000772956671507806 | COAD | Female-baised eQTL |
| rs36115975 | chr4:65325378:T:G | - | 0.0776241096992757 | 0.000772956671507806 | COAD | Female-baised eQTL |
| rs34010515 | chr4:65327196:G:T | - | 0.0776305601560716 | 0.000776524928180889 | COAD | Female-baised eQTL |
| rs13106741 | chr4:65329021:G:C | - | 0.0776371620677082 | 0.000781621832196334 | COAD | Female-baised eQTL |
| rs150831450 | chr4:65346674:C:T | - | 0.0776844097544699 | 0.000788952660532506 | COAD | Female-baised eQTL |
| rs139250980 | chr4:65346805:C:A | - | 0.0776844097544699 | 0.000788952660532506 | COAD | Female-baised eQTL |
| rs72640274 | chr4:65347671:C:T | - | 0.0776844097544699 | 0.000788952660532506 | COAD | Female-baised eQTL |
| rs34017095 | chr4:65327121:G:A | - | 0.0776502578311253 | 0.000791332776130399 | COAD | Female-baised eQTL |
| rs1868847 | chr4:65324714:A:G | - | 0.0728891026435291 | 0.00164986132012486 | COAD | Female-baised eQTL |
| rs7673345 | chr4:80915260:G:A | - | 0.0737374957514595 | 0.004575584622196 | COAD | Female-baised eQTL |
| rs2349722 | chr4:65335511:G:A | - | 0.0662252329942148 | 0.00470539305411819 | COAD | Female-baised eQTL |
| rs2122721 | chr4:65335679:G:A | - | 0.0662252329942148 | 0.00470539305411819 | COAD | Female-baised eQTL |
| rs28431185 | chr4:65333993:C:T | - | 0.0644585488703953 | 0.00606211206764138 | COAD | Female-baised eQTL |
| rs28760470 | chr4:65334012:C:G | - | 0.0644585488703953 | 0.00606211206764138 | COAD | Female-baised eQTL |
| rs73829196 | chr4:80913512:G:A | - | 0.0711192184128032 | 0.00640258283110735 | COAD | Female-baised eQTL |
| rs72864864 | chr4:80723119:G:A | - | 0.065004884491983 | 0.00904648207258505 | COAD | Female-baised eQTL |
| rs150245554 | chr4:67176501:G:A | - | 0.0678230773813435 | 0.00934427675345196 | COAD | Female-baised eQTL |
| rs4128522 | chr4:81695667:A:G | - | 0.0689831893967934 | 0.0094322538578708 | COAD | Female-baised eQTL |
| rs11721509 | chr4:76512735:A:G | - | 0.057605513674006 | 0.00967105527171489 | COAD | Female-baised eQTL |
| rs1868848 | chr4:65324473:G:A | - | 0.0596326689851717 | 0.0117185427265983 | COAD | Female-baised eQTL |
| rs34412857 | chr4:65324921:A:G | - | 0.0596326689851717 | 0.0117185427265983 | COAD | Female-baised eQTL |
| rs10155073 | chr4:65324926:T:C | - | 0.0596326689851717 | 0.0117185427265983 | COAD | Female-baised eQTL |
| rs7356402 | chr4:65325638:T:C | - | 0.0596326689851717 | 0.0117185427265983 | COAD | Female-baised eQTL |
| rs11729652 | chr4:76504952:T:C | - | 0.056320135647756 | 0.0118161978246483 | COAD | Female-baised eQTL |
| rs4859686 | chr4:76509376:C:T | - | 0.056320135647756 | 0.0118161978246483 | COAD | Female-baised eQTL |
| rs72659728 | chr4:76510004:T:A | - | 0.056320135647756 | 0.0118161978246483 | COAD | Female-baised eQTL |
| rs28399873 | chr4:65327996:T:C | - | 0.0596416905602803 | 0.0118387349931212 | COAD | Female-baised eQTL |
| rs34113823 | chr4:65330264:C:A | - | 0.0596473462563209 | 0.0118785978085302 | COAD | Female-baised eQTL |
| rs72659726 | chr4:76508363:A:G | - | 0.0539279952138374 | 0.0168462180106032 | COAD | Female-baised eQTL |
| rs111832566 | chr4:76471400:C:T | - | 0.0537751400556137 | 0.0172846229728963 | COAD | Female-baised eQTL |
| rs57661457 | chr4:76477215:C:T | - | 0.0537751400556137 | 0.0172846229728963 | COAD | Female-baised eQTL |
| rs7696146 | chr4:83772122:T:G | - | -0.0693118826526449 | 0.0174217580389379 | COAD | Female-baised eQTL |
| rs11725982 | chr4:80639411:A:T | - | -0.0591588837195691 | 0.0179466309120834 | COAD | Female-baised eQTL |
| rs7668296 | chr4:76504163:A:T | - | 0.0528220424225783 | 0.0198705779488731 | COAD | Female-baised eQTL |
| rs4859678 | chr4:76465219:G:T | - | 0.0526624555455579 | 0.020355839327862 | COAD | Female-baised eQTL |
| rs72889732 | chr4:81693599:C:A | - | 0.0527285491722375 | 0.0208600337882327 | COAD | Female-baised eQTL |
| rs11733728 | chr4:80681411:A:G | - | -0.0575910102552325 | 0.0216414182969541 | COAD | Female-baised eQTL |
| rs4693613 | chr4:80666480:G:A | - | -0.0575899497987281 | 0.0217341073566948 | COAD | Female-baised eQTL |
| rs4569745 | chr4:80674427:T:C | - | -0.0575899497987281 | 0.0217341073566948 | COAD | Female-baised eQTL |
| rs329396 | chr4:80699441:C:T | - | -0.0575899497987281 | 0.0217341073566948 | COAD | Female-baised eQTL |
| rs10013105 | chr4:80642987:A:G | - | -0.0575880581373037 | 0.0219206184932931 | COAD | Female-baised eQTL |
| rs13142089 | chr4:80519358:C:T | - | 0.046750464558739 | 0.0244660549057268 | COAD | Female-baised eQTL |
| rs35936345 | chr4:80519451:C:T | - | 0.046750464558739 | 0.0244660549057268 | COAD | Female-baised eQTL |
| rs444680 | chr4:80703061:T:C | - | -0.0561077960599019 | 0.0260910311664545 | COAD | Female-baised eQTL |
| rs329403 | chr4:80709461:C:T | - | -0.0561077960599019 | 0.0260910311664545 | COAD | Female-baised eQTL |
| rs59684133 | chr4:75682243:C:T | - | 0.0501910088138759 | 0.0270745076268992 | COAD | Female-baised eQTL |
| rs2172879 | chr4:80489895:C:T | - | 0.046096995961104 | 0.0271345130245581 | COAD | Female-baised eQTL |
| rs6833553 | chr4:80491182:G:A | - | 0.046096995961104 | 0.0271345130245581 | COAD | Female-baised eQTL |
| rs11099248 | chr4:80495598:T:C | - | 0.046096995961104 | 0.0271345130245581 | COAD | Female-baised eQTL |
| rs71596010 | chr4:80497603:T:C | - | 0.046096995961104 | 0.0271345130245581 | COAD | Female-baised eQTL |
| rs13112370 | chr4:80506282:A:G | - | 0.046096995961104 | 0.0271345130245581 | COAD | Female-baised eQTL |
| rs57613126 | chr4:66625735:T:C | - | 0.044433245648945 | 0.0291388887318895 | COAD | Female-baised eQTL |
| rs11131645 | chr4:66627174:A:G | - | 0.044433245648945 | 0.0291388887318895 | COAD | Female-baised eQTL |
| rs1510750 | chr4:66628569:A:G | - | 0.044433245648945 | 0.0291388887318895 | COAD | Female-baised eQTL |
| rs10517991 | chr4:66629716:G:A | - | 0.044433245648945 | 0.0291388887318895 | COAD | Female-baised eQTL |
| rs140567466 | chr4:76482601:T:C | - | 0.0491384511917836 | 0.0314064222122896 | COAD | Female-baised eQTL |
| rs138193746 | chr4:76483320:T:A | - | 0.0491384511917836 | 0.0314064222122896 | COAD | Female-baised eQTL |
| rs113655773 | chr4:76484342:G:A | - | 0.0491384511917836 | 0.0314064222122896 | COAD | Female-baised eQTL |
| rs7689683 | chr4:81662826:C:A | - | 0.0492291078254744 | 0.0314316388441574 | COAD | Female-baised eQTL |
| rs6535075 | chr4:80641952:T:C | - | -0.0546876215363089 | 0.0315120406816636 | COAD | Female-baised eQTL |
| rs6535076 | chr4:80641999:T:C | - | -0.0546876215363089 | 0.0315120406816636 | COAD | Female-baised eQTL |
| rs12646242 | chr4:80645206:G:A | - | -0.0546876215363089 | 0.0315120406816636 | COAD | Female-baised eQTL |
| rs4146322 | chr4:80647490:A:G | - | -0.0546876215363089 | 0.0315120406816636 | COAD | Female-baised eQTL |
| rs72888000 | chr4:81666933:C:T | - | 0.049230836290268 | 0.0316797463713814 | COAD | Female-baised eQTL |
| rs6851828 | chr4:65334452:C:A | - | 0.0511042870253158 | 0.0338753960876006 | COAD | Female-baised eQTL |
| rs72900468 | chr4:66636959:C:T | - | 0.0433992697305848 | 0.0346885078183288 | COAD | Female-baised eQTL |
| rs6855317 | chr4:80364780:G:A | - | 0.0557273205695665 | 0.0352442273822422 | COAD | Female-baised eQTL |
| rs72889705 | chr4:81668077:A:T | - | 0.0483024033673884 | 0.0356905572068833 | COAD | Female-baised eQTL |
| rs72887918 | chr4:81659939:T:C | - | 0.0482958453553018 | 0.0362192210346476 | COAD | Female-baised eQTL |
| rs58730702 | chr4:81703673:A:G | - | 0.0482767455042704 | 0.0365552617920789 | COAD | Female-baised eQTL |
| rs28534741 | chr4:80753872:C:T | - | 0.0533945942299174 | 0.0381890721830505 | COAD | Female-baised eQTL |
| rs17004986 | chr4:80746741:G:C | - | 0.0521219498567806 | 0.0443607953507904 | COAD | Female-baised eQTL |
| rs35067850 | chr4:80736218:G:T | - | 0.0419914351426219 | 0.0493897187448985 | COAD | Female-baised eQTL |
| rs144487237 | chr4:80736778:A:G | - | 0.0419914351426219 | 0.0493897187448985 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs116335178 | chr4:67073410:A:G | - | 0.144961249935267 | 0.0226658112162794 | READ | Male-baised eQTL |
| rs78593510 | chr4:67056998:T:A | - | 0.135909253997136 | 0.0414388796050981 | READ | Male-baised eQTL |
| rs79958152 | chr4:67062197:C:G | - | 0.131051571453478 | 0.0486547875938093 | READ | Male-baised eQTL |
| rs77144177 | chr4:71329177:T:C | - | 0.177162339605692 | 8.6911405110403e-08 | LUAD | Male-baised eQTL |
| rs12644090 | chr4:71333693:A:T | - | 0.177162339605692 | 8.6911405110403e-08 | LUAD | Male-baised eQTL |
| rs73826242 | chr4:71334227:G:C | - | 0.177089689277685 | 8.98522806460368e-08 | LUAD | Male-baised eQTL |
| rs16846228 | chr4:71289950:T:C | - | 0.169201782232662 | 3.76146636295601e-07 | LUAD | Male-baised eQTL |
| rs112084159 | chr4:71282327:C:G | - | 0.158448085825598 | 2.01111814695261e-06 | LUAD | Male-baised eQTL |
| rs16846223 | chr4:71286797:C:T | - | 0.158448085825598 | 2.01111814695261e-06 | LUAD | Male-baised eQTL |
| rs73826229 | chr4:71287011:A:G | - | 0.158448085825598 | 2.01111814695261e-06 | LUAD | Male-baised eQTL |
| rs12640827 | chr4:71288908:T:C | - | 0.158448085825598 | 2.01111814695261e-06 | LUAD | Male-baised eQTL |
| rs16846229 | chr4:71292409:G:A | - | 0.158448085825598 | 2.01111814695261e-06 | LUAD | Male-baised eQTL |
| rs111583239 | chr4:71293050:C:A | - | 0.158448085825598 | 2.01111814695261e-06 | LUAD | Male-baised eQTL |
| rs16846246 | chr4:71305102:C:T | - | 0.158448085825598 | 2.01111814695261e-06 | LUAD | Male-baised eQTL |
| rs75988374 | chr4:71306309:G:A | - | 0.158448085825598 | 2.01111814695261e-06 | LUAD | Male-baised eQTL |
| rs116766210 | chr4:71311033:G:A | - | 0.153306612849393 | 2.82960320456773e-06 | LUAD | Male-baised eQTL |
| rs114807475 | chr4:71311609:G:A | - | 0.153306612849393 | 2.82960320456773e-06 | LUAD | Male-baised eQTL |
| rs1452895 | chr4:71316490:G:A | - | 0.153306612849393 | 2.82960320456773e-06 | LUAD | Male-baised eQTL |
| rs3911269 | chr4:71316594:C:T | - | 0.153306612849393 | 2.82960320456773e-06 | LUAD | Male-baised eQTL |
| rs73826240 | chr4:71319729:C:A | - | 0.154852756329109 | 3.08630837652041e-06 | LUAD | Male-baised eQTL |
| rs10518087 | chr4:71319873:A:G | - | 0.154852756329109 | 3.08630837652041e-06 | LUAD | Male-baised eQTL |
| rs4336192 | chr4:71321178:T:G | - | 0.154852756329109 | 3.08630837652041e-06 | LUAD | Male-baised eQTL |
| rs57348036 | chr4:71324791:C:T | - | 0.154852756329109 | 3.08630837652041e-06 | LUAD | Male-baised eQTL |
| rs79093972 | chr4:71312314:C:T | - | 0.152866756416047 | 3.411473791088e-06 | LUAD | Male-baised eQTL |
| rs1377286 | chr4:71317929:G:A | - | 0.135555956635842 | 5.52094895428605e-05 | LUAD | Male-baised eQTL |
| rs79460153 | chr4:65390680:G:T | - | 0.116561419531977 | 9.87036183162535e-05 | LUAD | Male-baised eQTL |
| rs6815061 | chr4:66475469:G:C | - | 0.110757360240965 | 0.000220430205964083 | LUAD | Male-baised eQTL |
| rs11723418 | chr4:65401061:T:A | - | 0.110108723715207 | 0.000271295852167004 | LUAD | Male-baised eQTL |
| rs76947748 | chr4:71311890:T:C | - | 0.111492087829084 | 0.000969570551641437 | LUAD | Male-baised eQTL |
| rs17002297 | chr4:76961278:C:T | - | 0.0753030174086983 | 0.00144663361327413 | LUAD | Male-baised eQTL |
| rs11931411 | chr4:71330156:A:C | - | -0.108277482177775 | 0.00144978526550914 | LUAD | Male-baised eQTL |
| rs12509258 | chr4:76952275:A:G | - | 0.0749898383151696 | 0.00157954126855866 | LUAD | Male-baised eQTL |
| rs1901709 | chr4:71283313:G:A | - | 0.10718576401816 | 0.00200644614844064 | LUAD | Male-baised eQTL |
| rs1156585 | chr4:71285091:G:A | - | 0.10718576401816 | 0.00200644614844064 | LUAD | Male-baised eQTL |
| rs1901712 | chr4:71281586:T:G | - | 0.107071468048563 | 0.00203579490199763 | LUAD | Male-baised eQTL |
| rs980518 | chr4:71314698:G:A | - | 0.103112478212348 | 0.00272305235343708 | LUAD | Male-baised eQTL |
| rs58596754 | chr4:76959694:T:A | - | 0.0718663265321345 | 0.00272763234109949 | LUAD | Male-baised eQTL |
| rs2579318 | chr4:71286043:T:C | - | 0.104660117761098 | 0.00276132296974374 | LUAD | Male-baised eQTL |
| rs2579341 | chr4:71293409:C:A | - | 0.104660117761098 | 0.00276132296974374 | LUAD | Male-baised eQTL |
| rs930754 | chr4:71297417:T:C | - | 0.104660117761098 | 0.00276132296974374 | LUAD | Male-baised eQTL |
| rs2602054 | chr4:71298469:C:T | - | 0.104660117761098 | 0.00276132296974374 | LUAD | Male-baised eQTL |
| rs2602058 | chr4:71302238:G:A | - | 0.104660117761098 | 0.00276132296974374 | LUAD | Male-baised eQTL |
| rs9684793 | chr4:71324287:T:C | - | -0.103315519294892 | 0.00303288859386201 | LUAD | Male-baised eQTL |
| rs980519 | chr4:71315106:G:A | - | 0.101331636667618 | 0.00330523836034475 | LUAD | Male-baised eQTL |
| rs17001163 | chr4:75890878:T:C | - | 0.081023122506748 | 0.00398654397106796 | LUAD | Male-baised eQTL |
| rs4241597 | chr4:76980972:A:G | - | 0.0697101298023882 | 0.00428395560512633 | LUAD | Male-baised eQTL |
| rs28436183 | chr4:75890022:G:T | - | 0.0812356556457629 | 0.0046274174586004 | LUAD | Male-baised eQTL |
| rs28406986 | chr4:75892519:G:A | - | 0.0813826939424237 | 0.00464009079178707 | LUAD | Male-baised eQTL |
| rs35565943 | chr4:75893684:C:T | - | 0.0813826939424237 | 0.00464009079178707 | LUAD | Male-baised eQTL |
| rs55738856 | chr4:75895343:C:T | - | 0.0813826939424237 | 0.00464009079178707 | LUAD | Male-baised eQTL |
| rs56141568 | chr4:75895444:T:A | - | 0.0813826939424237 | 0.00464009079178707 | LUAD | Male-baised eQTL |
| rs35011483 | chr4:75904380:G:A | - | 0.0810458129734017 | 0.00474350708136797 | LUAD | Male-baised eQTL |
| rs79479530 | chr4:65397470:G:A | - | 0.0894843438686675 | 0.00521885835373783 | LUAD | Male-baised eQTL |
| rs28453978 | chr4:75898073:G:A | - | 0.0792568621584769 | 0.00613166740010411 | LUAD | Male-baised eQTL |
| rs77779002 | chr4:67172605:G:A | - | 0.0869956378576205 | 0.00967593991106889 | LUAD | Male-baised eQTL |
| rs62317203 | chr4:66932143:T:C | - | 0.0778095343970739 | 0.0100993128959768 | LUAD | Male-baised eQTL |
| rs11099226 | chr4:80417942:G:A | - | 0.0786898142860183 | 0.0103476159458224 | LUAD | Male-baised eQTL |
| rs6824830 | chr4:69619909:C:T | - | -0.0657847163517142 | 0.0136823122745901 | LUAD | Male-baised eQTL |
| rs13129549 | chr4:69626861:C:A | - | -0.0657847163517142 | 0.0136823122745901 | LUAD | Male-baised eQTL |
| rs6844389 | chr4:66935022:A:C | - | 0.0743357253234281 | 0.0137679274165819 | LUAD | Male-baised eQTL |
| rs2087020 | chr4:80554568:G:C | - | 0.115376883930952 | 0.0140282599131326 | LUAD | Male-baised eQTL |
| rs1118341 | chr4:80556630:C:A | - | 0.115376883930952 | 0.0140282599131326 | LUAD | Male-baised eQTL |
| rs35219270 | chr4:75893281:T:C | - | 0.0720691622498531 | 0.0162233675355526 | LUAD | Male-baised eQTL |
| rs7438682 | chr4:75893314:A:G | - | 0.0720691622498531 | 0.0162233675355526 | LUAD | Male-baised eQTL |
| rs4283653 | chr4:80570351:A:G | - | -0.114094747141549 | 0.0164091631179075 | LUAD | Male-baised eQTL |
| rs10011912 | chr4:69614609:T:C | - | -0.0649327034060685 | 0.016573950058751 | LUAD | Male-baised eQTL |
| rs10009530 | chr4:69614617:A:C | - | -0.0649327034060685 | 0.016573950058751 | LUAD | Male-baised eQTL |
| rs6832167 | chr4:69608592:G:A | - | -0.0645680058572918 | 0.0165900882267106 | LUAD | Male-baised eQTL |
| rs77311064 | chr4:67154496:G:A | - | 0.0809243091775672 | 0.0182579727521127 | LUAD | Male-baised eQTL |
| rs79541659 | chr4:67160454:C:A | - | 0.0809223651378953 | 0.0183592446152594 | LUAD | Male-baised eQTL |
| rs6825917 | chr4:80562562:C:G | - | -0.111713039795505 | 0.0184336021712016 | LUAD | Male-baised eQTL |
| rs6535014 | chr4:80563237:G:A | - | -0.111713039795505 | 0.0184336021712016 | LUAD | Male-baised eQTL |
| rs11940084 | chr4:80570030:C:A | - | -0.111713039795505 | 0.0184336021712016 | LUAD | Male-baised eQTL |
| rs1601513 | chr4:80572969:C:T | - | -0.111713039795505 | 0.0184336021712016 | LUAD | Male-baised eQTL |
| rs1601512 | chr4:80573232:A:G | - | -0.111713039795505 | 0.0184336021712016 | LUAD | Male-baised eQTL |
| rs9995032 | chr4:80575747:G:C | - | -0.111713039795505 | 0.0184336021712016 | LUAD | Male-baised eQTL |
| rs7686350 | chr4:66928418:C:T | - | 0.0728673534217815 | 0.0186223417149047 | LUAD | Male-baised eQTL |
| rs1980186 | chr4:82489469:C:T | - | -0.118146805114035 | 0.0205266103372692 | LUAD | Male-baised eQTL |
| rs1432335 | chr4:69640665:G:A | - | -0.0649302059623002 | 0.0210728232409321 | LUAD | Male-baised eQTL |
| rs17618230 | chr4:69630339:G:A | - | 0.0646393103598268 | 0.0220018807406757 | LUAD | Male-baised eQTL |
| rs13145525 | chr4:66920817:G:C | - | 0.0696277656536013 | 0.0238257529500794 | LUAD | Male-baised eQTL |
| rs62317175 | chr4:66921098:A:G | - | 0.0696277656536013 | 0.0238257529500794 | LUAD | Male-baised eQTL |
| rs113474266 | chr4:66926304:C:T | - | 0.0695703217749376 | 0.0243259434926212 | LUAD | Male-baised eQTL |
| rs4367198 | chr4:76595167:T:C | - | 0.058206912102201 | 0.0262227332899629 | LUAD | Male-baised eQTL |
| rs4623033 | chr4:76596204:A:G | - | 0.058206912102201 | 0.0262227332899629 | LUAD | Male-baised eQTL |
| rs17674565 | chr4:69629215:G:A | - | 0.0621667442092421 | 0.0302242815431136 | LUAD | Male-baised eQTL |
| rs4473712 | chr4:69623086:A:C | - | -0.0621667442092421 | 0.0302242815431136 | LUAD | Male-baised eQTL |
| rs1597611 | chr4:65398584:G:A | - | 0.0733364052833922 | 0.0310293160818553 | LUAD | Male-baised eQTL |
| rs1560605 | chr4:69645709:G:C | - | -0.0622869270712685 | 0.032266571462576 | LUAD | Male-baised eQTL |
| rs56248930 | chr4:76613285:A:T | - | 0.0571122864018426 | 0.0327265888233133 | LUAD | Male-baised eQTL |
| rs7662309 | chr4:69636262:C:T | - | -0.0616400819431186 | 0.0328539347277242 | LUAD | Male-baised eQTL |
| rs4397016 | chr4:76594724:T:G | - | 0.0566335041500483 | 0.0328889846536581 | LUAD | Male-baised eQTL |
| rs1583243 | chr4:69614065:G:A | - | -0.0613397657869037 | 0.0353239048327963 | LUAD | Male-baised eQTL |
| rs6600791 | chr4:69609338:C:T | - | -0.0605598241027863 | 0.0377243484610037 | LUAD | Male-baised eQTL |
| rs116418527 | chr4:69650609:A:T | - | 0.0601732500122686 | 0.042757290435263 | LUAD | Male-baised eQTL |
| rs13122577 | chr4:69581213:A:G | - | -0.0575709010040956 | 0.0442830077077927 | LUAD | Male-baised eQTL |
| rs10017134 | chr4:69591303:T:C | - | -0.0572526888048781 | 0.0464471958408876 | LUAD | Male-baised eQTL |
| rs1905966 | chr4:80565452:T:A | - | -0.0918058524641447 | 0.0471389380867251 | LUAD | Male-baised eQTL |
| rs2218206 | chr4:67864428:C:T | - | 0.0515222380967522 | 0.0476149720676351 | LUAD | Male-baised eQTL |
| rs7659937 | chr4:69648307:C:A | - | -0.0591239078313421 | 0.048144376712834 | LUAD | Male-baised eQTL |
| rs6818162 | chr4:67873093:C:G | - | -0.0501322743788638 | 0.0483379047047461 | LUAD | Male-baised eQTL |
| rs4286604 | chr4:69576447:A:G | - | -0.0568833526217977 | 0.0484906822806714 | LUAD | Male-baised eQTL |
| rs11249450 | chr4:69579639:C:T | - | -0.0569083661710322 | 0.0489219269867477 | LUAD | Male-baised eQTL |
| rs6843815 | chr4:69583152:A:T | - | -0.0567578122836326 | 0.0496800472064612 | LUAD | Male-baised eQTL |
| rs10518114 | chr4:73449142:G:A | - | 0.0629010262148092 | 0.00227912733995441 | COAD | Male-baised eQTL |
| rs12642086 | chr4:80140160:G:A | - | 0.0543477987080588 | 0.00491049645775839 | COAD | Male-baised eQTL |
| rs56404216 | chr4:78083698:G:A | - | 0.0545550777402781 | 0.00692657978881399 | COAD | Male-baised eQTL |
| rs17002926 | chr4:78083761:G:C | - | 0.0545550777402781 | 0.00692657978881399 | COAD | Male-baised eQTL |
| rs17002927 | chr4:78085012:A:G | - | 0.0545550777402781 | 0.00692657978881399 | COAD | Male-baised eQTL |
| rs148684131 | chr4:78087160:C:T | - | 0.0545550777402781 | 0.00692657978881399 | COAD | Male-baised eQTL |
| rs142243362 | chr4:78087530:G:C | - | 0.0545550777402781 | 0.00692657978881399 | COAD | Male-baised eQTL |
| rs146444092 | chr4:78088578:C:A | - | 0.0545550777402781 | 0.00692657978881399 | COAD | Male-baised eQTL |
| rs10026071 | chr4:78089824:T:C | - | 0.0545550777402781 | 0.00692657978881399 | COAD | Male-baised eQTL |
| rs114389084 | chr4:78095696:G:A | - | 0.053058555622479 | 0.00860262278568803 | COAD | Male-baised eQTL |
| rs28825502 | chr4:78096709:G:A | - | 0.053058555622479 | 0.00860262278568803 | COAD | Male-baised eQTL |
| rs17002937 | chr4:78099843:A:G | - | 0.053058555622479 | 0.00860262278568803 | COAD | Male-baised eQTL |
| rs17453030 | chr4:78104544:G:A | - | 0.053058555622479 | 0.00860262278568803 | COAD | Male-baised eQTL |
| rs10027675 | chr4:78112154:G:A | - | 0.053058555622479 | 0.00860262278568803 | COAD | Male-baised eQTL |
| rs192042871 | chr4:78114278:G:A | - | 0.053058555622479 | 0.00860262278568803 | COAD | Male-baised eQTL |
| rs147253513 | chr4:78116368:T:C | - | 0.053058555622479 | 0.00860262278568803 | COAD | Male-baised eQTL |
| rs147097526 | chr4:78117708:G:C | - | 0.053058555622479 | 0.00860262278568803 | COAD | Male-baised eQTL |
| rs56069998 | chr4:78118547:G:A | - | 0.053058555622479 | 0.00860262278568803 | COAD | Male-baised eQTL |
| rs56209110 | chr4:78118837:C:T | - | 0.053058555622479 | 0.00860262278568803 | COAD | Male-baised eQTL |
| rs28640590 | chr4:78126384:C:T | - | 0.053058555622479 | 0.00860262278568803 | COAD | Male-baised eQTL |
| rs28627481 | chr4:78126519:A:G | - | 0.053058555622479 | 0.00860262278568803 | COAD | Male-baised eQTL |
| rs28624340 | chr4:78127756:A:G | - | 0.053058555622479 | 0.00860262278568803 | COAD | Male-baised eQTL |
| rs10014790 | chr4:78150434:C:T | - | 0.053058555622479 | 0.00860262278568803 | COAD | Male-baised eQTL |
| rs9307350 | chr4:78150634:G:A | - | 0.053058555622479 | 0.00860262278568803 | COAD | Male-baised eQTL |
| rs10029277 | chr4:78151395:A:C | - | 0.053058555622479 | 0.00860262278568803 | COAD | Male-baised eQTL |
| rs10032397 | chr4:78154626:G:A | - | 0.053058555622479 | 0.00860262278568803 | COAD | Male-baised eQTL |
| rs77877857 | chr4:78131956:A:T | - | 0.0530475623951796 | 0.00865486677848272 | COAD | Male-baised eQTL |
| rs10009577 | chr4:78137118:G:A | - | 0.0530475623951796 | 0.00865486677848272 | COAD | Male-baised eQTL |
| rs10008346 | chr4:78139610:A:T | - | 0.0516095532040857 | 0.0106735715446513 | COAD | Male-baised eQTL |
| rs17002972 | chr4:78140406:C:T | - | 0.0516095532040857 | 0.0106735715446513 | COAD | Male-baised eQTL |
| rs187201889 | chr4:78140682:T:C | - | 0.0516095532040857 | 0.0106735715446513 | COAD | Male-baised eQTL |
| rs28542863 | chr4:78146221:C:A | - | 0.0516095532040857 | 0.0106735715446513 | COAD | Male-baised eQTL |
| rs6850590 | chr4:77947884:T:A | - | -0.0439522946147805 | 0.011263622739296 | COAD | Male-baised eQTL |
| rs6533359 | chr4:77948024:T:A | - | -0.0439522946147805 | 0.011263622739296 | COAD | Male-baised eQTL |
| rs4473672 | chr4:77920951:G:T | - | 0.0439522946147805 | 0.011263622739296 | COAD | Male-baised eQTL |
| rs4331798 | chr4:77921012:G:A | - | 0.0439522946147805 | 0.011263622739296 | COAD | Male-baised eQTL |
| rs58054752 | chr4:77925190:C:T | - | 0.0439522946147805 | 0.011263622739296 | COAD | Male-baised eQTL |
| rs57221952 | chr4:77926851:C:T | - | 0.0439522946147805 | 0.011263622739296 | COAD | Male-baised eQTL |
| rs11732039 | chr4:77927031:C:T | - | 0.0439522946147805 | 0.011263622739296 | COAD | Male-baised eQTL |
| rs11734428 | chr4:77929066:C:T | - | 0.0439522946147805 | 0.011263622739296 | COAD | Male-baised eQTL |
| rs73827459 | chr4:77930321:A:C | - | 0.0439522946147805 | 0.011263622739296 | COAD | Male-baised eQTL |
| rs73827460 | chr4:77931037:C:T | - | 0.0439522946147805 | 0.011263622739296 | COAD | Male-baised eQTL |
| rs1039467 | chr4:77937156:G:A | - | 0.0439522946147805 | 0.011263622739296 | COAD | Male-baised eQTL |
| rs1847216 | chr4:77937964:A:G | - | 0.0439522946147805 | 0.011263622739296 | COAD | Male-baised eQTL |
| rs2134459 | chr4:77940672:G:A | - | 0.0439522946147805 | 0.011263622739296 | COAD | Male-baised eQTL |
| rs6830993 | chr4:77915474:A:T | - | 0.0439477183560385 | 0.011489846893298 | COAD | Male-baised eQTL |
| rs73827456 | chr4:77915032:A:G | - | 0.0439484867850695 | 0.0115620745923469 | COAD | Male-baised eQTL |
| rs72860700 | chr4:78167473:T:A | - | 0.0489114979312229 | 0.0130494775293941 | COAD | Male-baised eQTL |
| rs17002965 | chr4:78139161:C:A | - | 0.0502331224892464 | 0.0130822460428748 | COAD | Male-baised eQTL |
| rs28433896 | chr4:78163465:G:A | - | 0.0487353607295809 | 0.0152065418098613 | COAD | Male-baised eQTL |
| rs10222693 | chr4:78164843:A:T | - | 0.0487353607295809 | 0.0152065418098613 | COAD | Male-baised eQTL |
| rs10222691 | chr4:78164817:A:C | - | 0.0477533880717873 | 0.0154128208185039 | COAD | Male-baised eQTL |
| rs28673365 | chr4:78165058:A:G | - | 0.0477533880717873 | 0.0154128208185039 | COAD | Male-baised eQTL |
| rs2867009 | chr4:78165549:C:T | - | 0.0477533880717873 | 0.0154128208185039 | COAD | Male-baised eQTL |
| rs1553386 | chr4:77954683:G:A | - | -0.0418132623321573 | 0.016177894234503 | COAD | Male-baised eQTL |
| rs3860617 | chr4:77938252:G:A | - | 0.0441126489718697 | 0.0163425258772409 | COAD | Male-baised eQTL |
| rs10440393 | chr4:78149059:A:C | - | 0.0482008094561797 | 0.0168417028475636 | COAD | Male-baised eQTL |
| rs28728167 | chr4:78159896:A:G | - | 0.0475049394506628 | 0.0180921709030179 | COAD | Male-baised eQTL |
| rs12648709 | chr4:76131696:T:C | - | 0.0512532597203145 | 0.0191747006081539 | COAD | Male-baised eQTL |
| rs13111705 | chr4:76172905:A:G | - | 0.0512010093185213 | 0.0195551880435933 | COAD | Male-baised eQTL |
| rs185716590 | chr4:77883189:A:T | - | 0.0426886790374372 | 0.019994983181542 | COAD | Male-baised eQTL |
| rs1441920 | chr4:76238564:A:G | - | 0.0414348831070809 | 0.0207978191143578 | COAD | Male-baised eQTL |
| rs16999974 | chr4:74875166:G:A | - | 0.0410399184782678 | 0.0215839413566969 | COAD | Male-baised eQTL |
| rs72857296 | chr4:74878872:T:C | - | 0.0410399184782678 | 0.0215839413566969 | COAD | Male-baised eQTL |
| rs4417999 | chr4:77908795:G:A | - | 0.0423552797992848 | 0.0220918788521286 | COAD | Male-baised eQTL |
| rs200185252 | chr4:77883188:A:T | - | 0.0419417608539988 | 0.0225117009036405 | COAD | Male-baised eQTL |
| rs58218398 | chr4:77868445:G:A | - | 0.0419102830038898 | 0.0225800130621328 | COAD | Male-baised eQTL |
| rs141154199 | chr4:77871344:G:A | - | 0.0419102830038898 | 0.0225800130621328 | COAD | Male-baised eQTL |
| rs57868780 | chr4:77876179:G:A | - | 0.0419102830038898 | 0.0225800130621328 | COAD | Male-baised eQTL |
| rs111665483 | chr4:77878810:C:T | - | 0.0419102830038898 | 0.0225800130621328 | COAD | Male-baised eQTL |
| rs146645753 | chr4:77889196:T:C | - | 0.0419102830038898 | 0.0225800130621328 | COAD | Male-baised eQTL |
| rs141441096 | chr4:77889506:C:T | - | 0.0419102830038898 | 0.0225800130621328 | COAD | Male-baised eQTL |
| rs11723221 | chr4:77899619:A:G | - | 0.0418987421941246 | 0.0229770577552517 | COAD | Male-baised eQTL |
| rs36035650 | chr4:76162197:G:A | - | 0.0497252177138193 | 0.0234464216088174 | COAD | Male-baised eQTL |
| rs35583533 | chr4:76163436:T:C | - | 0.0497252177138193 | 0.0234464216088174 | COAD | Male-baised eQTL |
| rs4859428 | chr4:76170440:G:A | - | 0.0497252177138193 | 0.0234464216088174 | COAD | Male-baised eQTL |
| rs13119254 | chr4:76173990:A:G | - | 0.0497245328773772 | 0.02345031852056 | COAD | Male-baised eQTL |
| rs3796497 | chr4:76174870:A:T | - | 0.0497245328773772 | 0.02345031852056 | COAD | Male-baised eQTL |
| rs3755890 | chr4:76161929:A:T | - | 0.049715417367316 | 0.0235594673920636 | COAD | Male-baised eQTL |
| rs71607345 | chr4:76235144:C:G | - | 0.0397417606869645 | 0.0241425900392393 | COAD | Male-baised eQTL |
| rs11721383 | chr4:77901916:C:T | - | 0.0413245236729241 | 0.0247812004053399 | COAD | Male-baised eQTL |
| rs1980266 | chr4:77821837:T:C | - | -0.0411711490213733 | 0.0251384210338736 | COAD | Male-baised eQTL |
| rs1554457 | chr4:77822056:G:T | - | -0.0411711490213733 | 0.0251384210338736 | COAD | Male-baised eQTL |
| rs3849580 | chr4:77822723:A:G | - | -0.0411711490213733 | 0.0251384210338736 | COAD | Male-baised eQTL |
| rs6822317 | chr4:77825557:T:A | - | -0.0411711490213733 | 0.0251384210338736 | COAD | Male-baised eQTL |
| rs13131896 | chr4:77828777:G:A | - | -0.0411711490213733 | 0.0251384210338736 | COAD | Male-baised eQTL |
| rs16846228 | chr4:71289950:T:C | - | 0.0542176488783288 | 0.025246586807588 | COAD | Male-baised eQTL |
| rs11729703 | chr4:77909988:T:C | - | 0.0411443687195656 | 0.0258994812527841 | COAD | Male-baised eQTL |
| rs34334700 | chr4:76175690:C:T | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs12641190 | chr4:76177785:T:C | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs4452450 | chr4:76178019:G:T | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs4634246 | chr4:76178077:C:T | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs2869854 | chr4:76178520:C:T | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs1470191 | chr4:76178591:C:A | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs1470192 | chr4:76178746:A:G | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs6851995 | chr4:76179119:T:C | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs894247 | chr4:76179290:A:G | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs894248 | chr4:76179748:A:G | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs1470193 | chr4:76180084:T:C | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs4859624 | chr4:76180595:T:C | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs2304813 | chr4:76180819:G:A | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs2304814 | chr4:76180853:C:G | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs1441923 | chr4:76182376:T:C | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs13117802 | chr4:76182776:G:T | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs67653006 | chr4:76183124:T:C | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs2034003 | chr4:76184163:C:T | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs35783378 | chr4:76184269:C:T | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs72857046 | chr4:76184463:C:T | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs72857048 | chr4:76184758:A:G | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs67917805 | chr4:76184893:A:T | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs17001588 | chr4:76184984:G:C | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs17001589 | chr4:76185068:T:C | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs4859627 | chr4:76185426:C:T | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs4859628 | chr4:76185659:G:A | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs4859629 | chr4:76185915:G:A | - | 0.0483193462075166 | 0.0278588789197147 | COAD | Male-baised eQTL |
| rs11721932 | chr4:70286618:A:G | - | 0.0375933770653298 | 0.0279124183030731 | COAD | Male-baised eQTL |
| rs17002978 | chr4:78152546:C:G | - | 0.0446506149208211 | 0.027920437386347 | COAD | Male-baised eQTL |
| rs17002823 | chr4:77833279:T:C | - | 0.0404488976684182 | 0.028035474657665 | COAD | Male-baised eQTL |
| rs55886549 | chr4:77836363:A:G | - | 0.0404488976684182 | 0.028035474657665 | COAD | Male-baised eQTL |
| rs57246363 | chr4:77836727:A:G | - | 0.0404488976684182 | 0.028035474657665 | COAD | Male-baised eQTL |
| rs79663426 | chr4:77837281:C:T | - | 0.0404488976684182 | 0.028035474657665 | COAD | Male-baised eQTL |
| rs17002825 | chr4:77839331:T:C | - | 0.0404488976684182 | 0.028035474657665 | COAD | Male-baised eQTL |
| rs77414115 | chr4:77841090:G:C | - | 0.0404488976684182 | 0.028035474657665 | COAD | Male-baised eQTL |
| rs17002829 | chr4:77841985:C:T | - | 0.0404488976684182 | 0.028035474657665 | COAD | Male-baised eQTL |
| rs17002831 | chr4:77844420:T:C | - | 0.0404488976684182 | 0.028035474657665 | COAD | Male-baised eQTL |
| rs1402626 | chr4:77846179:A:G | - | 0.0404488976684182 | 0.028035474657665 | COAD | Male-baised eQTL |
| rs55694923 | chr4:77847199:T:G | - | 0.0404488976684182 | 0.028035474657665 | COAD | Male-baised eQTL |
| rs112208963 | chr4:77849109:C:T | - | 0.0404488976684182 | 0.028035474657665 | COAD | Male-baised eQTL |
| rs56896076 | chr4:76240479:C:G | - | 0.0393812577987364 | 0.0286104043613336 | COAD | Male-baised eQTL |
| rs1390738 | chr4:78560424:T:G | - | -0.0265462089901033 | 0.028779678215426 | COAD | Male-baised eQTL |
| rs4859869 | chr4:77705117:T:G | - | -0.0394656655781424 | 0.0310333570245651 | COAD | Male-baised eQTL |
| rs11730329 | chr4:77849791:C:T | - | 0.0397454072681128 | 0.0312734352863766 | COAD | Male-baised eQTL |
| rs11730403 | chr4:77849966:C:T | - | 0.0397454072681128 | 0.0312734352863766 | COAD | Male-baised eQTL |
| rs6533290 | chr4:77850794:G:A | - | 0.0397454072681128 | 0.0312734352863766 | COAD | Male-baised eQTL |
| rs4078523 | chr4:77851621:A:T | - | 0.0397454072681128 | 0.0312734352863766 | COAD | Male-baised eQTL |
| rs11733759 | chr4:77852552:C:T | - | 0.0397454072681128 | 0.0312734352863766 | COAD | Male-baised eQTL |
| rs7657658 | chr4:77853436:C:T | - | 0.0397454072681128 | 0.0312734352863766 | COAD | Male-baised eQTL |
| rs12643198 | chr4:76242273:G:A | - | 0.0387394540090631 | 0.0315366641930411 | COAD | Male-baised eQTL |
| rs4859646 | chr4:76244858:T:C | - | 0.0387394540090631 | 0.0315366641930411 | COAD | Male-baised eQTL |
| rs78586815 | chr4:76247291:G:A | - | 0.0387394540090631 | 0.0315366641930411 | COAD | Male-baised eQTL |
| rs2053487 | chr4:76176183:C:T | - | 0.0463685773959796 | 0.0336053045073846 | COAD | Male-baised eQTL |
| rs4859871 | chr4:77707061:T:C | - | -0.0387939730695297 | 0.0343059824227817 | COAD | Male-baised eQTL |
| rs2866689 | chr4:77715033:G:A | - | -0.0387939730695297 | 0.0343059824227817 | COAD | Male-baised eQTL |
| rs13138341 | chr4:77707955:A:G | - | -0.0387875725150024 | 0.0344966623252687 | COAD | Male-baised eQTL |
| rs6820885 | chr4:64418915:G:C | - | -0.0526719292917028 | 0.0350670002825959 | COAD | Male-baised eQTL |
| rs17002971 | chr4:78140310:T:C | - | 0.0426215404721087 | 0.0367037337175548 | COAD | Male-baised eQTL |
| rs28438642 | chr4:78141766:G:C | - | 0.0426215404721087 | 0.0367037337175548 | COAD | Male-baised eQTL |
| rs10020175 | chr4:78142523:T:A | - | 0.0426215404721087 | 0.0367037337175548 | COAD | Male-baised eQTL |
| rs4859437 | chr4:76252942:T:A | - | 0.0374507333174063 | 0.0381791636757274 | COAD | Male-baised eQTL |
| rs72607829 | chr4:71779569:G:A | - | 0.0620875207036168 | 0.0392414085745029 | COAD | Male-baised eQTL |
| rs1383429 | chr4:78990336:A:G | - | -0.0375797215324716 | 0.0393018049894174 | COAD | Male-baised eQTL |
| rs885376 | chr4:77711605:A:T | - | -0.0376079492841253 | 0.0406070355821696 | COAD | Male-baised eQTL |
| rs72860675 | chr4:78158614:G:A | - | 0.0414385875194097 | 0.0409190857307951 | COAD | Male-baised eQTL |
| rs4859623 | chr4:76169335:C:T | - | 0.0444532647809841 | 0.0418460730365014 | COAD | Male-baised eQTL |
| rs1521419 | chr4:77840046:A:T | - | 0.0377963875752999 | 0.0420163290674397 | COAD | Male-baised eQTL |
| rs1470194 | chr4:76180225:A:C | - | 0.043361520227466 | 0.0475585511128826 | COAD | Male-baised eQTL |
| rs12650752 | chr4:78555722:G:A | - | -0.0281757574485628 | 0.0482150885877274 | COAD | Male-baised eQTL |
| rs970630 | chr4:64423298:C:T | - | -0.049214780942364 | 0.0493839731081405 | COAD | Male-baised eQTL |
| rs12648686 | chr4:78555721:T:C | - | -0.0279934606053158 | 0.0496165365964039 | COAD | Male-baised eQTL |
| rs1496593 | chr4:78558529:G:A | - | -0.0279934606053158 | 0.0496165365964039 | COAD | Male-baised eQTL |
| rs1496590 | chr4:78559264:A:G | - | -0.0279934606053158 | 0.0496165365964039 | COAD | Male-baised eQTL |
| rs982603 | chr4:64426773:A:T | - | -0.0491990299417153 | 0.0496491920415479 | COAD | Male-baised eQTL |
| rs982373 | chr4:64430137:A:G | - | -0.0491990299417153 | 0.0496491920415479 | COAD | Male-baised eQTL |
| rs2714945 | chr4:64433242:T:G | - | -0.0491990299417153 | 0.0496491920415479 | COAD | Male-baised eQTL |
| rs1496591 | chr4:78558728:C:T | - | -0.0280052717069579 | 0.0498751470049391 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of PPBP |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000163736 | PPBP | C0020517 | Hypersensitivity | 1 | CTD_human |
| ENSG00000163736 | PPBP | C0020538 | Hypertensive disease | 2 | CTD_human |
| ENSG00000163736 | PPBP | C0024121 | Lung Neoplasms | 1 | CTD_human |
| ENSG00000163736 | PPBP | C0242379 | Malignant neoplasm of lung | 1 | CTD_human |
| ENSG00000163736 | PPBP | C1527304 | Allergic Reaction | 1 | CTD_human |
