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Gene: ENSG00000162896 |
Summary for PIGR |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000162896 | Gene symbol | PIGR |
| Gene name | polymeric immunoglobulin receptor | |
| HGNC | 8968 | |
| Entrez ID | 5284 | |
| Gene type | protein_coding | |
| Synonyms | PIGR| | |
| UniProtAcc | P01833 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for PIGR |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
 |
| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| PIGR | 2.85e+03 | -3.93e+00 | 7.57e-01 | -5.19e+00 | 2.06e-07 | 1.81e-05 | BRCA |
| PIGR | 4.16e+01 | 2.40e+00 | 3.22e-01 | 7.47e+00 | 7.87e-14 | 2.98e-11 | SARC |
| PIGR | 7.76e+01 | 2.45e+00 | 6.74e-01 | 3.64e+00 | 2.72e-04 | 1.90e-02 | MESO |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| PIGR | 1.16e+05 | -1.81e+00 | 5.14e-01 | -3.52e+00 | 4.38e-04 | 1.36e-03 | STAD |
| PIGR | 1.34e+05 | 2.29e+00 | 3.37e-01 | 6.80e+00 | 1.08e-11 | 8.07e-11 | KIRP |
| PIGR | 3.64e+03 | -1.53e+00 | 6.66e-01 | -2.29e+00 | 2.17e-02 | 4.80e-02 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| PIGR | 5.30e+03 | -2.30e+00 | 2.66e-01 | -8.61e+00 | 7.05e-18 | 2.19e-17 | BRCA |
Top |
Sex-biased somatic mutation for PIGR |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for PIGR |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg02105856 | chr1:206946439 | CGI:chr1:206909348-206909857 | UTR,promoter,exon,gene body | 5.08e-01 | 3.81e-01 | 1.97e+00 | 4.94e-02 | 4.97e-02 | 1.27e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg02105856 | chr1:206946439 | CGI:chr1:206909348-206909857 | UTR,promoter,exon,gene body | 3.85e-01 | 2.73e-01 | 4.90e+00 | 9.78e-07 | 3.57e-06 | 1.12e-01 |
| KIRC | cg00961792 | chr1:206947062 | CGI:chr1:206909348-206909857 | promoter | 6.18e-01 | 7.19e-01 | -5.52e+00 | 3.33e-08 | 1.97e-07 | -1.01e-01 |
| KIRC | cg01965508 | chr1:206947283 | CGI:chr1:206909348-206909857 | promoter | 7.48e-01 | 8.53e-01 | -4.91e+00 | 9.24e-07 | 3.39e-06 | -1.05e-01 |
| HNSC | cg02105856 | chr1:206946439 | CGI:chr1:206909348-206909857 | UTR,promoter,exon,gene body | 5.63e-01 | 6.70e-01 | -2.90e+00 | 3.76e-03 | 5.57e-03 | -1.07e-01 |
| LUSC | cg02105856 | chr1:206946439 | CGI:chr1:206909348-206909857 | UTR,promoter,exon,gene body | 6.33e-01 | 4.37e-01 | 3.40e+00 | 6.84e-04 | 2.02e-03 | 1.97e-01 |
| LUSC | cg12751565 | chr1:206946642 | CGI:chr1:206909348-206909857 | promoter | 7.56e-01 | 5.95e-01 | 3.64e+00 | 2.77e-04 | 1.16e-03 | 1.62e-01 |
| LUSC | cg01965508 | chr1:206947283 | CGI:chr1:206909348-206909857 | promoter | 6.75e-01 | 7.95e-01 | -2.96e+00 | 3.10e-03 | 5.73e-03 | -1.21e-01 |
| BLCA | cg01965508 | chr1:206947283 | CGI:chr1:206909348-206909857 | promoter | 6.14e-01 | 7.34e-01 | -2.70e+00 | 6.95e-03 | 1.06e-02 | -1.19e-01 |
| LIHC | cg01965508 | chr1:206947283 | CGI:chr1:206909348-206909857 | promoter | 6.17e-01 | 7.25e-01 | -2.98e+00 | 2.93e-03 | 4.10e-03 | -1.08e-01 |
| CHOL | cg12751565 | chr1:206946642 | CGI:chr1:206909348-206909857 | promoter | 6.15e-01 | 4.69e-01 | 2.21e+00 | 2.70e-02 | 3.50e-02 | 1.46e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg12751565 | chr1:206946642 | CGI:chr1:206909348-206909857 | promoter | 7.75e-01 | 6.66e-01 | 8.96e+00 | 3.14e-19 | 1.59e-18 | 1.08e-01 |
| BRCA | cg00961792 | chr1:206947062 | CGI:chr1:206909348-206909857 | promoter | 6.75e-01 | 5.72e-01 | 9.25e+00 | 2.16e-20 | 1.21e-19 | 1.03e-01 |
| COAD | cg02105856 | chr1:206946439 | CGI:chr1:206909348-206909857 | UTR,promoter,exon,gene body | 4.01e-01 | 2.48e-01 | 2.47e+00 | 1.36e-02 | 1.97e-02 | 1.53e-01 |
| COAD | cg12751565 | chr1:206946642 | CGI:chr1:206909348-206909857 | promoter | 4.85e-01 | 3.39e-01 | 2.10e+00 | 3.55e-02 | 3.91e-02 | 1.46e-01 |
| COAD | cg01965508 | chr1:206947283 | CGI:chr1:206909348-206909857 | promoter | 5.18e-01 | 3.57e-01 | 2.68e+00 | 7.43e-03 | 1.27e-02 | 1.61e-01 |
| LIHC | cg12751565 | chr1:206946642 | CGI:chr1:206909348-206909857 | promoter | 5.79e-01 | 4.72e-01 | 2.29e+00 | 2.20e-02 | 2.60e-02 | 1.06e-01 |
Top |
Exon skipping events with PSI in TCGA for PIGR |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
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| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for PIGR |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for PIGR |
| TFs related to PIGR. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| CHOL | FOXD2 | PIGR | 2.87e+00 | 2.84e-03 | 4.11e+00 | 9.87e-01 | Female-biased |
| CHOL | HNF1B | PIGR | 3.52e+00 | 7.54e-03 | 4.53e+00 | 9.87e-01 | Female-biased |
| CHOL | HOXA9 | PIGR | 3.54e+00 | 8.06e-03 | 4.52e+00 | 9.86e-01 | Female-biased |
| CHOL | ZNF35 | PIGR | 2.44e+00 | 1.18e-03 | 3.87e+00 | 9.84e-01 | Female-biased |
| PAAD | FOXD2 | PIGR | 4.50e+00 | 9.88e-01 | 3.54e+00 | 5.27e-03 | Male-biased |
| PAAD | FOXM1 | PIGR | 4.18e+00 | 9.81e-01 | 3.30e+00 | 7.75e-03 | Male-biased |
| PAAD | SOX17 | PIGR | 4.60e+00 | 9.83e-01 | 3.79e+00 | 1.07e-02 | Male-biased |
| PAAD | SOX6 | PIGR | 4.63e+00 | 9.82e-01 | 3.84e+00 | 1.24e-02 | Male-biased |
| PAAD | STAT2 | PIGR | 4.13e+00 | 9.87e-01 | 2.87e+00 | 1.09e-03 | Male-biased |
| PAAD | ZNF35 | PIGR | 4.24e+00 | 9.80e-01 | 3.39e+00 | 9.19e-03 | Male-biased |
| PAAD | ZNF570 | PIGR | 3.87e+00 | 9.80e-01 | 2.75e+00 | 2.17e-03 | Male-biased |
| PAAD | ZNF677 | PIGR | 4.19e+00 | 9.84e-01 | 3.24e+00 | 5.31e-03 | Male-biased |
| PCPG | AIRE | PIGR | 4.28e+00 | 9.86e-01 | 3.26e+00 | 3.64e-03 | Male-biased |
| PCPG | FOXD2 | PIGR | 3.97e+00 | 9.83e-01 | 2.67e+00 | 8.97e-04 | Male-biased |
| PCPG | HNF1B | PIGR | 4.48e+00 | 9.87e-01 | 3.52e+00 | 4.95e-03 | Male-biased |
| PCPG | HOXA9 | PIGR | 4.53e+00 | 9.91e-01 | 3.40e+00 | 2.27e-03 | Male-biased |
| PCPG | SOX17 | PIGR | 4.01e+00 | 9.83e-01 | 2.87e+00 | 2.00e-03 | Male-biased |
| PCPG | SOX6 | PIGR | 4.16e+00 | 9.86e-01 | 3.03e+00 | 2.24e-03 | Male-biased |
| SKCM | ESR2 | PIGR | 2.70e+00 | 1.44e-03 | 4.27e+00 | 9.80e-01 | Female-biased |
| SKCM | HNF1B | PIGR | 4.50e+00 | 9.82e-01 | 3.29e+00 | 6.11e-03 | Male-biased |
| SKCM | HOXA9 | PIGR | 4.55e+00 | 9.86e-01 | 3.06e+00 | 2.67e-03 | Male-biased |
| SKCM | IRF8 | PIGR | 4.59e+00 | 9.80e-01 | 3.51e+00 | 8.93e-03 | Male-biased |
| SKCM | IRF9 | PIGR | 4.40e+00 | 9.81e-01 | 3.14e+00 | 5.21e-03 | Male-biased |
| SKCM | ZNF479 | PIGR | 2.62e+00 | 8.59e-04 | 4.34e+00 | 9.83e-01 | Female-biased |
| PIGR related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for PIGR |
| RBPs related to ES in PIGR. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| READ | ZC3H10 | exon_skip_36589 | 7.35e+00 | 7.38e-03 | 7.71e+00 | 9.83e-01 | Female-biased |
| PIGR related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000162896 | AC007126.1,hsa-mir-4728,PIGR | Male-specific ceRNA | TCGA-STAD |
| ENSG00000162896 | SLIT3-AS2,hsa-mir-4728,PIGR | Male-specific ceRNA | TCGA-STAD |
Top |
Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs12130746 | chr1:215800210:T:G | - | 0.328832126385716 | 0.0277078290235046 | PAAD | Female-baised eQTL |
| rs11120638 | chr1:215800807:A:G | - | 0.328832126385716 | 0.0277078290235046 | PAAD | Female-baised eQTL |
| rs10864202 | chr1:215802773:T:C | - | 0.328832126385716 | 0.0277078290235046 | PAAD | Female-baised eQTL |
| rs11120643 | chr1:215812617:T:C | - | 0.328832126385716 | 0.0277078290235046 | PAAD | Female-baised eQTL |
| rs12037735 | chr1:215814172:A:C | - | 0.328832126385716 | 0.0277078290235046 | PAAD | Female-baised eQTL |
| rs6691299 | chr1:215835574:T:C | - | 0.328832126385716 | 0.0277078290235046 | PAAD | Female-baised eQTL |
| rs11120660 | chr1:215839728:C:T | - | 0.328832126385716 | 0.0277078290235046 | PAAD | Female-baised eQTL |
| rs10864209 | chr1:215841581:C:T | - | 0.328832126385716 | 0.0277078290235046 | PAAD | Female-baised eQTL |
| rs1934426 | chr1:215857900:C:T | - | 0.328832126385716 | 0.0277078290235046 | PAAD | Female-baised eQTL |
| rs11120677 | chr1:215860708:T:C | - | 0.328832126385716 | 0.0277078290235046 | PAAD | Female-baised eQTL |
| rs12136240 | chr1:215860974:C:G | - | 0.328267483341675 | 0.0282871131305431 | PAAD | Female-baised eQTL |
| rs12126127 | chr1:215861138:T:C | - | 0.328267483341675 | 0.0282871131305431 | PAAD | Female-baised eQTL |
| rs12137382 | chr1:215862290:C:T | - | 0.328267483341675 | 0.0282871131305431 | PAAD | Female-baised eQTL |
| rs12127267 | chr1:215862438:T:C | - | 0.328267483341675 | 0.0282871131305431 | PAAD | Female-baised eQTL |
| rs77777820 | chr1:215804682:A:G | - | 0.302749376789505 | 0.0327721242649396 | PAAD | Female-baised eQTL |
| rs140453267 | chr1:200612915:T:C | - | 0.143386952457009 | 0.0267263283551234 | HNSC | Female-baised eQTL |
| rs80049124 | chr1:200567610:A:C | - | 0.137749632138455 | 0.0352070275031763 | HNSC | Female-baised eQTL |
| rs74675327 | chr1:200570581:C:T | - | 0.137749632138455 | 0.0352070275031763 | HNSC | Female-baised eQTL |
| rs59556650 | chr1:215759319:C:T | - | 0.198005266283421 | 0.0186129649587436 | LUSC | Female-baised eQTL |
| rs17025373 | chr1:215759615:G:A | - | 0.198005266283421 | 0.0186129649587436 | LUSC | Female-baised eQTL |
| rs61339549 | chr1:215761141:C:T | - | 0.198005266283421 | 0.0186129649587436 | LUSC | Female-baised eQTL |
| rs75107032 | chr1:215761960:G:A | - | 0.198005266283421 | 0.0186129649587436 | LUSC | Female-baised eQTL |
| rs80089696 | chr1:212388424:G:A | - | 0.215660655146951 | 0.0304557228856146 | LUSC | Female-baised eQTL |
| rs115768448 | chr1:212423120:A:G | - | 0.215660655146951 | 0.0304557228856146 | LUSC | Female-baised eQTL |
| rs10495005 | chr1:215764029:A:C | - | 0.197113889973028 | 0.0334592393701802 | LUSC | Female-baised eQTL |
| rs17025395 | chr1:215772229:G:A | - | 0.195907652630613 | 0.0359181963396108 | LUSC | Female-baised eQTL |
| rs75375609 | chr1:215764745:A:G | - | 0.19529565559559 | 0.0376185134122878 | LUSC | Female-baised eQTL |
| rs55869451 | chr1:215767197:T:G | - | 0.19529565559559 | 0.0376185134122878 | LUSC | Female-baised eQTL |
| rs17025389 | chr1:215768463:C:T | - | 0.19529565559559 | 0.0376185134122878 | LUSC | Female-baised eQTL |
| rs11583023 | chr1:201944599:T:C | - | 0.152067263767548 | 0.0489452733310831 | LUSC | Female-baised eQTL |
| rs144927621 | chr1:216126462:A:G | - | 0.0907872713624688 | 3.28126283164066e-05 | LUAD | Female-baised eQTL |
| rs11118976 | chr1:208041609:A:T | - | 0.0649765594527444 | 0.00234422793744404 | LUAD | Female-baised eQTL |
| rs10495017 | chr1:216127057:G:A | - | 0.062663766131996 | 0.00378122515926712 | LUAD | Female-baised eQTL |
| rs2274448 | chr1:208042959:C:A | - | 0.0602509461331916 | 0.00581115343109718 | LUAD | Female-baised eQTL |
| rs74152180 | chr1:208046200:T:C | - | 0.0571083700516071 | 0.010036952465771 | LUAD | Female-baised eQTL |
| rs411278 | chr1:212295632:A:G | - | 0.0558557189372399 | 0.0214192217973101 | LUAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs7367954 | chr1:205897973:C:T | - | 0.248532934855114 | 0.000636006880222855 | SARC | Male-baised eQTL |
| rs10494783 | chr1:198694532:G:A | - | 0.120234443992248 | 0.00133628467276349 | SARC | Male-baised eQTL |
| rs12742531 | chr1:198575600:C:A | - | 0.103399726960432 | 0.0077625429889459 | SARC | Male-baised eQTL |
| rs11586087 | chr1:198579795:G:A | - | 0.103399726960432 | 0.0077625429889459 | SARC | Male-baised eQTL |
| rs12747432 | chr1:198597424:G:T | - | 0.103399726960432 | 0.0077625429889459 | SARC | Male-baised eQTL |
| rs67306083 | chr1:198601013:C:T | - | 0.103399726960432 | 0.0077625429889459 | SARC | Male-baised eQTL |
| rs34544423 | chr1:198578103:C:G | - | 0.103432565041118 | 0.00779379079913723 | SARC | Male-baised eQTL |
| rs10801676 | chr1:198609440:T:C | - | 0.0988222077838703 | 0.0119532883627596 | SARC | Male-baised eQTL |
| rs12754047 | chr1:198613506:T:C | - | 0.0988222077838703 | 0.0119532883627596 | SARC | Male-baised eQTL |
| rs28398409 | chr1:198614892:A:G | - | 0.0988222077838703 | 0.0119532883627596 | SARC | Male-baised eQTL |
| rs35565915 | chr1:198617942:G:A | - | 0.0988222077838703 | 0.0119532883627596 | SARC | Male-baised eQTL |
| rs35736847 | chr1:198617961:T:C | - | 0.0988222077838703 | 0.0119532883627596 | SARC | Male-baised eQTL |
| rs35762735 | chr1:198618102:T:C | - | 0.0988222077838703 | 0.0119532883627596 | SARC | Male-baised eQTL |
| rs34364874 | chr1:198618114:T:A | - | 0.0988222077838703 | 0.0119532883627596 | SARC | Male-baised eQTL |
| rs35922693 | chr1:198618389:T:G | - | 0.0988222077838703 | 0.0119532883627596 | SARC | Male-baised eQTL |
| rs34335884 | chr1:198618397:G:A | - | 0.0988222077838703 | 0.0119532883627596 | SARC | Male-baised eQTL |
| rs16843463 | chr1:198618952:T:C | - | 0.0988222077838703 | 0.0119532883627596 | SARC | Male-baised eQTL |
| rs72736070 | chr1:198621236:C:T | - | 0.0988222077838703 | 0.0119532883627596 | SARC | Male-baised eQTL |
| rs16843471 | chr1:198621291:C:T | - | 0.0988222077838703 | 0.0119532883627596 | SARC | Male-baised eQTL |
| rs16843474 | chr1:198621324:A:C | - | 0.0988222077838703 | 0.0119532883627596 | SARC | Male-baised eQTL |
| rs12129000 | chr1:198622398:G:C | - | 0.0988222077838703 | 0.0119532883627596 | SARC | Male-baised eQTL |
| rs35536362 | chr1:198623075:G:A | - | 0.0988222077838703 | 0.0119532883627596 | SARC | Male-baised eQTL |
| rs12122584 | chr1:198614168:A:T | - | 0.0988566847263236 | 0.0119882774224809 | SARC | Male-baised eQTL |
| rs16843506 | chr1:198625114:A:G | - | 0.0988565895275374 | 0.0119882774224809 | SARC | Male-baised eQTL |
| rs34889541 | chr1:198625639:G:A | - | 0.0988565895275374 | 0.0119882774224809 | SARC | Male-baised eQTL |
| rs12139775 | chr1:198625652:C:T | - | 0.0988565895275374 | 0.0119882774224809 | SARC | Male-baised eQTL |
| rs12132271 | chr1:198625788:G:A | - | 0.0988565895275374 | 0.0119882774224809 | SARC | Male-baised eQTL |
| rs16843520 | chr1:198625969:A:G | - | 0.0988565895275374 | 0.0119882774224809 | SARC | Male-baised eQTL |
| rs12127588 | chr1:198626376:G:A | - | 0.0988565895275374 | 0.0119882774224809 | SARC | Male-baised eQTL |
| rs12126799 | chr1:198623799:A:T | - | 0.0988929713534952 | 0.012032060467637 | SARC | Male-baised eQTL |
| rs56967989 | chr1:198411489:A:G | - | 0.084606406794442 | 0.0295654979674074 | SARC | Male-baised eQTL |
| rs17018244 | chr1:211941727:T:G | - | 0.0859105559624821 | 0.036021836017945 | SARC | Male-baised eQTL |
| rs41330044 | chr1:197928095:G:A | - | 0.0858802995082674 | 0.0362243404484604 | SARC | Male-baised eQTL |
| rs13373920 | chr1:198406470:G:T | - | 0.0818207888578368 | 0.0388541437886675 | SARC | Male-baised eQTL |
| rs12411171 | chr1:198401337:T:C | - | 0.0792422683837689 | 0.049680261097425 | SARC | Male-baised eQTL |
| rs12404647 | chr1:198401769:C:G | - | 0.0792422683837689 | 0.049680261097425 | SARC | Male-baised eQTL |
| rs12402722 | chr1:198403241:G:T | - | 0.0792422683837689 | 0.049680261097425 | SARC | Male-baised eQTL |
| rs6698662 | chr1:214438380:G:T | - | 0.055315396976251 | 0.00010133583540694 | KIRC | Male-baised eQTL |
| rs1436884 | chr1:216900107:C:T | - | 0.0590132295795727 | 0.000154742048813517 | KIRC | Male-baised eQTL |
| rs6663535 | chr1:206972719:C:G | - | 0.0551539235852171 | 0.000369340444427178 | KIRC | Male-baised eQTL |
| rs6659170 | chr1:214993160:G:A | - | 0.0545605658344123 | 0.000424451168691973 | KIRC | Male-baised eQTL |
| rs199548431 | chr1:216490296:G:A | - | 0.0533710959190454 | 0.000913922287237474 | KIRC | Male-baised eQTL |
| rs201540294 | chr1:216490070:T:C | - | 0.0518047260441862 | 0.00137631709707485 | KIRC | Male-baised eQTL |
| rs7520864 | chr1:203665275:A:G | - | -0.0571252759014446 | 0.00148169711684482 | KIRC | Male-baised eQTL |
| rs7551412 | chr1:210961251:A:T | - | 0.0381196512951094 | 0.00208046026881712 | KIRC | Male-baised eQTL |
| rs12070742 | chr1:216491408:A:T | - | 0.0480435435364943 | 0.00304814589929946 | KIRC | Male-baised eQTL |
| rs12065971 | chr1:216491579:T:A | - | 0.0480435435364943 | 0.00304814589929946 | KIRC | Male-baised eQTL |
| rs112123781 | chr1:216492492:C:G | - | 0.0480435435364943 | 0.00304814589929946 | KIRC | Male-baised eQTL |
| rs6663814 | chr1:216485266:C:T | - | 0.0467284300959977 | 0.0042394472968263 | KIRC | Male-baised eQTL |
| rs6671570 | chr1:216485314:T:C | - | 0.0467284300959977 | 0.0042394472968263 | KIRC | Male-baised eQTL |
| rs141500484 | chr1:216488820:C:T | - | 0.0467284300959977 | 0.0042394472968263 | KIRC | Male-baised eQTL |
| rs147706336 | chr1:216485742:C:T | - | 0.0467253866553113 | 0.00425479638084165 | KIRC | Male-baised eQTL |
| rs7553997 | chr1:210961321:T:C | - | 0.0337661777526424 | 0.00475636321793983 | KIRC | Male-baised eQTL |
| rs150093062 | chr1:210987300:A:G | - | 0.031453874520556 | 0.00626002930194678 | KIRC | Male-baised eQTL |
| rs7529625 | chr1:210983356:T:C | - | 0.031410610503909 | 0.00662917804675639 | KIRC | Male-baised eQTL |
| rs6663672 | chr1:210984286:C:T | - | 0.031410610503909 | 0.00662917804675639 | KIRC | Male-baised eQTL |
| rs75986786 | chr1:210985397:C:T | - | 0.031410610503909 | 0.00662917804675639 | KIRC | Male-baised eQTL |
| rs10863872 | chr1:210986608:A:G | - | 0.031410610503909 | 0.00662917804675639 | KIRC | Male-baised eQTL |
| rs10863873 | chr1:210986643:T:C | - | 0.031410610503909 | 0.00662917804675639 | KIRC | Male-baised eQTL |
| rs6671367 | chr1:210988009:A:C | - | 0.031410610503909 | 0.00662917804675639 | KIRC | Male-baised eQTL |
| rs12043937 | chr1:210988160:A:G | - | 0.031410610503909 | 0.00662917804675639 | KIRC | Male-baised eQTL |
| rs12043952 | chr1:210988168:A:C | - | 0.031410610503909 | 0.00662917804675639 | KIRC | Male-baised eQTL |
| rs6659020 | chr1:210988184:C:T | - | 0.031410610503909 | 0.00662917804675639 | KIRC | Male-baised eQTL |
| rs7537597 | chr1:210983433:G:C | - | 0.0313399515884515 | 0.00708625788181886 | KIRC | Male-baised eQTL |
| rs12406562 | chr1:210969376:T:C | - | 0.0316655231495041 | 0.00841166551596369 | KIRC | Male-baised eQTL |
| rs12403500 | chr1:211002031:G:A | - | 0.0287819829545901 | 0.0150854040166481 | KIRC | Male-baised eQTL |
| rs6540648 | chr1:211036938:C:A | - | 0.0282849860274631 | 0.0157926695111254 | KIRC | Male-baised eQTL |
| rs6666342 | chr1:211035681:T:G | - | 0.0283871086021773 | 0.0158693113943677 | KIRC | Male-baised eQTL |
| rs183507111 | chr1:211032541:A:G | - | 0.0284302708912724 | 0.0161328371569369 | KIRC | Male-baised eQTL |
| rs58255417 | chr1:211036115:C:T | - | 0.0283349650528402 | 0.0161843510951652 | KIRC | Male-baised eQTL |
| rs11119668 | chr1:211036434:A:G | - | 0.0283349650528402 | 0.0161843510951652 | KIRC | Male-baised eQTL |
| rs12070402 | chr1:210992410:C:T | - | 0.0282060692281791 | 0.0183767136178256 | KIRC | Male-baised eQTL |
| rs1532682 | chr1:210993084:T:G | - | 0.0282060692281791 | 0.0183767136178256 | KIRC | Male-baised eQTL |
| rs12022715 | chr1:210994612:T:C | - | 0.0282060692281791 | 0.0183767136178256 | KIRC | Male-baised eQTL |
| rs11119654 | chr1:210995651:A:G | - | 0.0279136955624353 | 0.020491411276921 | KIRC | Male-baised eQTL |
| rs6687069 | chr1:210996631:C:G | - | 0.0279136955624353 | 0.020491411276921 | KIRC | Male-baised eQTL |
| rs6689715 | chr1:210996867:C:T | - | 0.0279136955624353 | 0.020491411276921 | KIRC | Male-baised eQTL |
| rs145184581 | chr1:211000628:A:C | - | 0.0279389641023755 | 0.0204971026131478 | KIRC | Male-baised eQTL |
| rs12027535 | chr1:211004805:T:G | - | 0.0279389641023755 | 0.0204971026131478 | KIRC | Male-baised eQTL |
| rs61850228 | chr1:211010610:T:A | - | 0.0278601618502189 | 0.0205572437660986 | KIRC | Male-baised eQTL |
| rs3767290 | chr1:205051769:T:G | - | 0.0415877120062779 | 0.0216027404879066 | KIRC | Male-baised eQTL |
| rs72749756 | chr1:204206239:C:T | - | 0.0376959823254792 | 0.0216192321348413 | KIRC | Male-baised eQTL |
| rs12022739 | chr1:210994743:T:C | - | 0.0273278927568522 | 0.0235693887492573 | KIRC | Male-baised eQTL |
| rs1501550 | chr1:210995417:G:A | - | 0.0270840612016949 | 0.0256176068211826 | KIRC | Male-baised eQTL |
| rs12087308 | chr1:205053079:C:G | - | 0.0401021127513276 | 0.025861488656597 | KIRC | Male-baised eQTL |
| rs1501549 | chr1:210995327:G:T | - | 0.0270481226791463 | 0.0260481499475922 | KIRC | Male-baised eQTL |
| rs147127384 | chr1:210955026:C:T | - | 0.0241846997674324 | 0.0276208304972016 | KIRC | Male-baised eQTL |
| rs35683927 | chr1:211001877:G:A | - | 0.0282207513683852 | 0.0285964653389781 | KIRC | Male-baised eQTL |
| rs34279520 | chr1:211001880:A:G | - | 0.0282207513683852 | 0.0285964653389781 | KIRC | Male-baised eQTL |
| rs12090204 | chr1:213907934:T:C | - | 0.0534456658335507 | 0.0314260485208802 | KIRC | Male-baised eQTL |
| rs12089197 | chr1:213908155:A:G | - | 0.0534456658335507 | 0.0314260485208802 | KIRC | Male-baised eQTL |
| rs12090665 | chr1:213909198:A:G | - | 0.0534439288308939 | 0.0314869367477827 | KIRC | Male-baised eQTL |
| rs1501548 | chr1:210995292:T:C | - | 0.0268548057106712 | 0.031998900773452 | KIRC | Male-baised eQTL |
| rs2075426 | chr1:213952398:G:C | - | 0.0437201850865782 | 0.0338390979791864 | KIRC | Male-baised eQTL |
| rs1501557 | chr1:210953359:C:T | - | 0.0234061842658598 | 0.0358825571441495 | KIRC | Male-baised eQTL |
| rs28771105 | chr1:210968666:G:C | - | 0.0230657621168903 | 0.0394828341894136 | KIRC | Male-baised eQTL |
| rs4951693 | chr1:210969221:A:C | - | 0.0230657621168903 | 0.0394828341894136 | KIRC | Male-baised eQTL |
| rs4951694 | chr1:210969329:C:T | - | 0.0230657621168903 | 0.0394828341894136 | KIRC | Male-baised eQTL |
| rs6676767 | chr1:205052541:A:G | - | 0.0373749131398334 | 0.0406024182612628 | KIRC | Male-baised eQTL |
| rs61820363 | chr1:209884750:G:A | - | 0.0724742321515952 | 0.0348681090094707 | BLCA | Male-baised eQTL |
| rs112973354 | chr1:213965235:C:G | - | 0.134723885611409 | 8.96941734229749e-05 | LUAD | Male-baised eQTL |
| rs74739430 | chr1:213927654:C:T | - | 0.129080399844244 | 0.000215069132125975 | LUAD | Male-baised eQTL |
| rs12028941 | chr1:210915132:C:T | - | 0.10284498472923 | 0.000428575822832851 | LUAD | Male-baised eQTL |
| rs61849000 | chr1:210947932:C:T | - | 0.0953837793824401 | 0.00329707530256212 | LUAD | Male-baised eQTL |
| rs9970445 | chr1:216777162:T:C | - | 0.0976457431923321 | 0.0116399816482477 | LUAD | Male-baised eQTL |
| rs12043579 | chr1:216770677:A:T | - | 0.0971961246733811 | 0.0125472050909065 | LUAD | Male-baised eQTL |
| rs77617852 | chr1:216773202:G:A | - | 0.0971961246733811 | 0.0125472050909065 | LUAD | Male-baised eQTL |
| rs79133455 | chr1:216773402:T:C | - | 0.0971961246733811 | 0.0125472050909065 | LUAD | Male-baised eQTL |
| rs12030905 | chr1:210917018:C:T | - | 0.0745981081037248 | 0.015591281982384 | LUAD | Male-baised eQTL |
| rs61848992 | chr1:210918507:C:T | - | 0.0745981081037248 | 0.015591281982384 | LUAD | Male-baised eQTL |
| rs57655345 | chr1:210935591:T:C | - | 0.0724290097511603 | 0.0166081339163542 | LUAD | Male-baised eQTL |
| rs2501891 | chr1:210480610:A:G | - | 0.0572470054608559 | 0.0177795400111448 | LUAD | Male-baised eQTL |
| rs2501890 | chr1:210480873:C:T | - | 0.0571419308664782 | 0.0189235622526325 | LUAD | Male-baised eQTL |
| rs4655473 | chr1:213937691:T:A | - | 0.110509489215327 | 0.0191108122786819 | LUAD | Male-baised eQTL |
| rs2501887 | chr1:210481739:A:G | - | 0.0569087478162263 | 0.0194611830533985 | LUAD | Male-baised eQTL |
| rs7522894 | chr1:210908708:G:A | - | 0.0716468158668992 | 0.0218331956768573 | LUAD | Male-baised eQTL |
| rs1572738 | chr1:216778545:G:A | - | 0.0893269785460217 | 0.0251381622958604 | LUAD | Male-baised eQTL |
| rs78975214 | chr1:216778273:A:T | - | 0.0902384867495605 | 0.0254113091130296 | LUAD | Male-baised eQTL |
| rs74517773 | chr1:216779988:T:G | - | 0.0902384867495605 | 0.0254113091130296 | LUAD | Male-baised eQTL |
| rs2358210 | chr1:210921492:T:C | - | 0.0694409842728274 | 0.0258339271248881 | LUAD | Male-baised eQTL |
| rs2068859 | chr1:213938866:C:T | - | 0.10599942602816 | 0.0262021731751043 | LUAD | Male-baised eQTL |
| rs4655475 | chr1:213945191:A:G | - | 0.10599942602816 | 0.0262021731751043 | LUAD | Male-baised eQTL |
| rs2501902 | chr1:210476543:A:G | - | 0.0540241492261818 | 0.0263222733944958 | LUAD | Male-baised eQTL |
| rs2501900 | chr1:210476942:T:C | - | 0.0540241492261818 | 0.0263222733944958 | LUAD | Male-baised eQTL |
| rs2501896 | chr1:210478633:A:G | - | 0.0540241492261818 | 0.0263222733944958 | LUAD | Male-baised eQTL |
| rs11119510 | chr1:210474758:T:G | - | 0.0538878955280422 | 0.0268200332056408 | LUAD | Male-baised eQTL |
| rs12038838 | chr1:210474786:C:G | - | 0.0538878955280422 | 0.0268200332056408 | LUAD | Male-baised eQTL |
| rs11582003 | chr1:210475058:G:A | - | 0.0538878955280422 | 0.0268200332056408 | LUAD | Male-baised eQTL |
| rs2501903 | chr1:210475234:T:G | - | 0.0538878955280422 | 0.0268200332056408 | LUAD | Male-baised eQTL |
| rs9438402 | chr1:205924571:T:C | - | 0.0796600331411814 | 0.0276172832792574 | LUAD | Male-baised eQTL |
| rs2501901 | chr1:210476874:A:C | - | 0.0538660982139981 | 0.0276425209073791 | LUAD | Male-baised eQTL |
| rs3811427 | chr1:205923283:T:C | - | 0.080305586088592 | 0.027824962944039 | LUAD | Male-baised eQTL |
| rs3811426 | chr1:205923287:C:T | - | 0.080305586088592 | 0.027824962944039 | LUAD | Male-baised eQTL |
| rs2075426 | chr1:213952398:G:C | - | 0.102751737391205 | 0.0282621802814039 | LUAD | Male-baised eQTL |
| rs2501892 | chr1:210480209:C:G | - | 0.0546592298671617 | 0.0292170416165682 | LUAD | Male-baised eQTL |
| rs2501899 | chr1:210477183:G:A | - | 0.0533559970323193 | 0.0303305087436463 | LUAD | Male-baised eQTL |
| rs2501898 | chr1:210477649:C:T | - | 0.0533559970323193 | 0.0303305087436463 | LUAD | Male-baised eQTL |
| rs2501897 | chr1:210477723:C:T | - | 0.0533559970323193 | 0.0303305087436463 | LUAD | Male-baised eQTL |
| rs742566 | chr1:210478028:C:T | - | 0.0533559970323193 | 0.0303305087436463 | LUAD | Male-baised eQTL |
| rs742565 | chr1:210478174:T:C | - | 0.0533559970323193 | 0.0303305087436463 | LUAD | Male-baised eQTL |
| rs2501895 | chr1:210479135:G:A | - | 0.0533559970323193 | 0.0303305087436463 | LUAD | Male-baised eQTL |
| rs2501894 | chr1:210479472:G:A | - | 0.0533559970323193 | 0.0303305087436463 | LUAD | Male-baised eQTL |
| rs2501904 | chr1:210474456:T:A | - | 0.0532245434731184 | 0.0308900792859642 | LUAD | Male-baised eQTL |
| rs1073570 | chr1:213922601:C:T | - | 0.0840780303956331 | 0.0331500057723353 | LUAD | Male-baised eQTL |
| rs4233316 | chr1:213922127:G:A | - | 0.0837484957343163 | 0.0347252197942591 | LUAD | Male-baised eQTL |
| rs1073569 | chr1:213922525:T:C | - | 0.0800916769844556 | 0.0347431002935989 | LUAD | Male-baised eQTL |
| rs12036375 | chr1:205924741:G:A | - | 0.0773151580114309 | 0.0359285581017439 | LUAD | Male-baised eQTL |
| rs9438403 | chr1:205925341:G:A | - | 0.0773151580114309 | 0.0359285581017439 | LUAD | Male-baised eQTL |
| rs12408607 | chr1:208379243:G:A | - | 0.0829793322977134 | 0.0364896638251921 | LUAD | Male-baised eQTL |
| rs12567977 | chr1:205925961:C:T | - | 0.0771369452498285 | 0.0370335765341566 | LUAD | Male-baised eQTL |
| rs6540636 | chr1:210947256:G:A | - | 0.0672729768497021 | 0.0411542843021093 | LUAD | Male-baised eQTL |
| rs12568779 | chr1:205928748:C:T | - | 0.082650384696207 | 0.041328672464814 | LUAD | Male-baised eQTL |
| rs12023503 | chr1:205933465:C:T | - | 0.0731338018302021 | 0.0472438605991391 | LUAD | Male-baised eQTL |
| rs2275325 | chr1:203831607:G:C | - | -0.0781326181023238 | 0.0200887126599873 | COAD | Male-baised eQTL |
| rs12123505 | chr1:203821921:C:G | - | 0.0749547937668419 | 0.0297414233538689 | COAD | Male-baised eQTL |
| rs11240552 | chr1:203811082:A:G | - | -0.071360893628985 | 0.0369765719767707 | COAD | Male-baised eQTL |
| rs10900520 | chr1:203811463:A:G | - | -0.071360893628985 | 0.0369765719767707 | COAD | Male-baised eQTL |
| rs4951022 | chr1:203815865:T:C | - | -0.0712462522251127 | 0.0369769924437805 | COAD | Male-baised eQTL |
| rs12026395 | chr1:203817676:T:C | - | -0.0721019574197407 | 0.0388682233735048 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000162896 |
| CpG Site: cg12751565 | |
| Position to Gene: promoter | |
| Male Effect: -0.478025709237656 | |
| Female Effect: - |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg12751565 | chr1:206946642 | promoter | -0.478025709237656 | 2.79432476333476e-12 | -0.49686929336985614 | 2.635166153825402e-15 | LUAD |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of PIGR |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
