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Gene: ENSG00000161179 |
Summary for YDJC |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000161179 | Gene symbol | YDJC |
| Gene name | YdjC chitooligosaccharide deacetylase homolog | |
| HGNC | 27158 | |
| Entrez ID | 150223 | |
| Gene type | protein_coding | |
| Synonyms | YDJC| | |
| UniProtAcc | A8MPS7 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
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Structure and expression level for YDJC |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
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| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
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| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| YDJC | 1.43e+03 | 1.03e+00 | 1.29e-01 | 8.00e+00 | 1.27e-15 | 1.58e-14 | HNSC |
| YDJC | 1.43e+03 | 1.00e+00 | 1.46e-01 | 6.89e+00 | 5.62e-12 | 4.39e-11 | KIRP |
| YDJC | 2.46e+03 | 1.12e+00 | 2.45e-01 | 4.58e+00 | 4.59e-06 | 8.38e-05 | ESCA |
| YDJC | 9.76e+02 | 1.19e+00 | 3.27e-01 | 3.65e+00 | 2.59e-04 | 1.03e-03 | CHOL |
| Differentially expressed gene analysis between tumor female and normal female samples. |
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| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| YDJC | 2.43e+03 | 1.12e+00 | 2.85e-01 | 3.93e+00 | 8.45e-05 | 7.82e-04 | STAD |
| YDJC | 1.09e+03 | 1.40e+00 | 8.54e-02 | 1.63e+01 | 5.69e-60 | 7.65e-59 | BRCA |
| YDJC | 1.97e+03 | 2.27e+00 | 4.06e-01 | 5.59e+00 | 2.25e-08 | 3.21e-07 | READ |
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Sex-biased somatic mutation for YDJC |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for YDJC |
| Landscape of DNA methylation across multiple cancer types. |
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| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| HNSC | cg01307115 | chr22:21628498 | CGI:chr22:21628497-21630195 | promoter,gene body,CDS,UTR,exon | 7.40e-01 | 8.73e-01 | -3.00e+00 | 2.68e-03 | 4.18e-03 | -1.33e-01 |
| HNSC | cg23469117 | chr22:21631357 | CGI:chr22:21628497-21630195 | promoter | 6.56e-01 | 7.66e-01 | -4.33e+00 | 1.47e-05 | 5.24e-05 | -1.10e-01 |
| LUSC | cg01307115 | chr22:21628498 | CGI:chr22:21628497-21630195 | promoter,gene body,CDS,UTR,exon | 7.22e-01 | 8.60e-01 | -2.49e+00 | 1.27e-02 | 1.67e-02 | -1.37e-01 |
| BLCA | cg01307115 | chr22:21628498 | CGI:chr22:21628497-21630195 | promoter,gene body,CDS,UTR,exon | 7.26e-01 | 8.57e-01 | -2.42e+00 | 1.57e-02 | 2.02e-02 | -1.31e-01 |
| BLCA | cg20703614 | chr22:21631145 | CGI:chr22:21628497-21630195 | promoter | 7.22e-01 | 8.69e-01 | -3.99e+00 | 6.56e-05 | 2.97e-04 | -1.47e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
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Exon skipping events with PSI in TCGA for YDJC |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
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| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| LUSC | exon_skip_367762 | 6.79e-01 | 8.05e-01 | -3.46e+00 | 5.31e-04 | 1.77e-03 | -1.26e-01 |
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RNA A-to-I editing events in TCGA for YDJC |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for YDJC |
| TFs related to YDJC. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| ACC | ZNF519 | YDJC | 4.08e+00 | 9.81e-01 | 3.24e+00 | 8.27e-03 | Male-biased |
| ACC | ZNF571 | YDJC | 3.99e+00 | 9.81e-01 | 3.12e+00 | 7.20e-03 | Male-biased |
| ACC | ZNF792 | YDJC | 4.09e+00 | 9.82e-01 | 3.25e+00 | 8.27e-03 | Male-biased |
| YDJC related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for YDJC |
| RBPs related to ES in YDJC. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| BLCA | ZC3H10 | exon_skip_367762 | 7.63e+00 | 9.86e-01 | 7.17e+00 | 4.28e-03 | Male-biased |
| YDJC related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs17432756 | chr22:27150956:T:G | - | 0.0592460793543399 | 0.0163087481333615 | LUAD | Female-baised eQTL |
| rs5997181 | chr22:27150810:C:T | - | 0.0638196372111612 | 0.0218123889427251 | LUAD | Female-baised eQTL |
| rs9625158 | chr22:27154678:C:G | - | 0.0607772009953705 | 0.0299052851674458 | LUAD | Female-baised eQTL |
| rs2205642 | chr22:27154528:A:G | - | 0.0589862708060905 | 0.0431438813887117 | LUAD | Female-baised eQTL |
| rs8139459 | chr22:22371876:A:C | - | 0.0413600085479457 | 0.0443186668616139 | LUAD | Female-baised eQTL |
| rs1963140 | chr22:27289583:A:G | - | -0.0835647644904021 | 0.0233156093525187 | COAD | Female-baised eQTL |
| rs7293113 | chr22:27286666:G:A | - | -0.0961513828487973 | 0.0399505722425231 | COAD | Female-baised eQTL |
| rs5751710 | chr22:23686440:C:T | - | -0.076914946934615 | 0.0442360574649248 | COAD | Female-baised eQTL |
| rs6003843 | chr22:23688612:T:C | - | -0.076914946934615 | 0.0442360574649248 | COAD | Female-baised eQTL |
| rs2070446 | chr22:23693783:C:T | - | -0.0781406301712533 | 0.0445897285459978 | COAD | Female-baised eQTL |
| rs7291730 | chr22:23654892:T:C | - | -0.0671587912423953 | 0.0476266789740343 | COAD | Female-baised eQTL |
| rs9624263 | chr22:23652594:A:G | - | -0.0668011595628208 | 0.0495230308914077 | COAD | Female-baised eQTL |
| rs7290210 | chr22:23652694:T:A | - | -0.0668011595628208 | 0.0495230308914077 | COAD | Female-baised eQTL |
| rs10854772 | chr22:23653610:G:A | - | -0.0668011595628208 | 0.0495230308914077 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs79097951 | chr22:18143897:G:A | - | 0.089942565788666 | 0.00524139316730336 | LUSC | Male-baised eQTL |
| rs143823861 | chr22:28037247:C:A | - | 0.0655267967075249 | 0.0135407130321291 | KIRC | Male-baised eQTL |
| rs75650828 | chr22:28019667:G:A | - | 0.110422684149398 | 0.0208657050202161 | KIRC | Male-baised eQTL |
| rs8138623 | chr22:28010684:C:G | - | 0.110302199922674 | 0.0211662375122878 | KIRC | Male-baised eQTL |
| rs79037983 | chr22:28063677:G:A | - | 0.0908571020749818 | 0.0435522494772273 | KIRC | Male-baised eQTL |
| rs5752799 | chr22:28792052:A:T | - | 0.074427655844318 | 0.0485764064387079 | KIRC | Male-baised eQTL |
| rs7293171 | chr22:31406338:T:C | - | 0.0417962659089492 | 0.0380411893042027 | BLCA | Male-baised eQTL |
| rs12152166 | chr22:31354912:G:A | - | 0.0413780900335129 | 0.0447033264272336 | BLCA | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000161179 |
| CpG Site: cg01307115 | |
| Position to Gene: gene,CDS,UTR,promoter,exon | |
| Male Effect: - | |
| Female Effect: -0.301024399176399 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg01307115 | chr22:21628498 | gene,CDS,UTR,promoter,exon | -0.301024399176399 | 7.91864772455515e-06 | -0.3520747829300516 | 7.438744253516222e-09 | LUAD |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_367762 | chr22:21629009:21629187 | Frame-shift | rs2073449 | chr22:22196484:T:C | Distant upstream | 0.0647695792618526 | 0.0234355991821127 | LUAD | Male-baised sQTL |
| exon_skip_367762 | chr22:21629009:21629187 | Frame-shift | rs2266965 | chr22:21766866:A:G | Distant upstream | 0.0364029462264086 | 0.0343637396504306 | HNSC | Male-baised sQTL |
| exon_skip_367762 | chr22:21629009:21629187 | Frame-shift | rs5755008 | chr22:21755633:C:T | Distant upstream | 0.0826168726451958 | 0.0181401338559665 | BLCA | Male-baised sQTL |
| exon_skip_367762 | chr22:21629009:21629187 | Frame-shift | rs5755040 | chr22:21757611:T:A | Distant upstream | 0.0826168726451958 | 0.0181401338559665 | BLCA | Male-baised sQTL |
| exon_skip_367762 | chr22:21629009:21629187 | Frame-shift | rs2276005 | chr22:21759399:T:G | Distant upstream | 0.0826168726451958 | 0.0181401338559665 | BLCA | Male-baised sQTL |
| exon_skip_367762 | chr22:21629009:21629187 | Frame-shift | rs2276006 | chr22:21759598:G:T | Distant upstream | 0.0826168726451958 | 0.0181401338559665 | BLCA | Male-baised sQTL |
| exon_skip_367762 | chr22:21629009:21629187 | Frame-shift | rs5749811 | chr22:21753576:C:T | Distant upstream | 0.0825331773346525 | 0.0184711874962852 | BLCA | Male-baised sQTL |
| exon_skip_367762 | chr22:21629009:21629187 | Frame-shift | rs5754968 | chr22:21751293:C:G | Distant upstream | 0.0818209431497011 | 0.0233469002878219 | BLCA | Male-baised sQTL |
| exon_skip_367762 | chr22:21629009:21629187 | Frame-shift | rs5754970 | chr22:21751687:C:T | Distant upstream | 0.0816857743861112 | 0.023971722937775 | BLCA | Male-baised sQTL |
| exon_skip_367762 | chr22:21629009:21629187 | Frame-shift | rs596235 | chr22:20629305:T:C | Distant downstream | 0.0408470082069526 | 0.0296563032518539 | BLCA | Male-baised sQTL |
| exon_skip_367762 | chr22:21629009:21629187 | Frame-shift | rs9610228 | chr22:21749134:T:A | Distant upstream | 0.0739919385889399 | 0.0321082801572748 | BLCA | Male-baised sQTL |
| exon_skip_367762 | chr22:21629009:21629187 | Frame-shift | rs5749792 | chr22:21748744:A:G | Distant upstream | 0.0778825022768463 | 0.0417658391887831 | BLCA | Male-baised sQTL |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of YDJC |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
