|
||||||
|
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Gene: ENSG00000155849 |
Summary for ELMO1 |
Gene summary |
| Gene information | Ensembl ID | ENSG00000155849 | Gene symbol | ELMO1 |
| Gene name | engulfment and cell motility 1 | |
| HGNC | 16286 | |
| Entrez ID | 9844 | |
| Gene type | protein_coding | |
| Synonyms | ELMO1|KIAA0281|CED12|ELMO-1|CED-12 | |
| UniProtAcc | Q92556 |
Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for ELMO1 |
AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure.∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
Landscape of gene expressions across multiple cancer types. |
Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
Differentially expressed gene analysis between tumor male and normal male samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| ELMO1 | 1.05e+03 | -1.73e+00 | 3.69e-01 | -4.68e+00 | 2.89e-06 | 1.87e-05 | CHOL |
Differentially expressed gene analysis between tumor female and normal female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| ELMO1 | 1.24e+03 | -1.05e+00 | 1.44e-01 | -7.30e+00 | 2.97e-13 | 1.89e-12 | LUAD |
Top |
Sex-biased somatic mutation for ELMO1 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
Top |
DNA methylation with beta values for ELMO1 |
Landscape of DNA methylation across multiple cancer types. |
Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg04136149 | chr7:37449333 | CGI:chr7:37447751-37449069 | promoter | 2.58e-01 | 4.49e-01 | -2.29e+00 | 2.20e-02 | 3.63e-02 | -1.91e-01 |
| BLCA | cg06159352 | chr7:37448010 | CGI:chr7:37447751-37449069 | promoter,gene body | 4.87e-01 | 3.71e-01 | 3.41e+00 | 6.49e-04 | 3.62e-03 | 1.16e-01 |
| BLCA | cg00159100 | chr7:37448030 | CGI:chr7:37447751-37449069 | promoter,gene body | 3.56e-01 | 2.52e-01 | 3.85e+00 | 1.16e-04 | 7.83e-04 | 1.04e-01 |
| BLCA | cg11372090 | chr7:37449057 | CGI:chr7:37447751-37449069 | UTR,promoter,exon,gene body | 3.80e-01 | 2.71e-01 | 3.49e+00 | 4.77e-04 | 2.78e-03 | 1.09e-01 |
Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| LUAD | cg16230141 | chr7:37448559 | CGI:chr7:37447751-37449069 | promoter,gene body | 1.72e-01 | 4.27e-02 | 2.76e+00 | 5.70e-03 | 8.35e-03 | 1.30e-01 |
| LUAD | cg11372090 | chr7:37449057 | CGI:chr7:37447751-37449069 | UTR,promoter,exon,gene body | 2.72e-01 | 8.10e-02 | 2.41e+00 | 1.59e-02 | 1.96e-02 | 1.91e-01 |
| LUAD | cg15947096 | chr7:37449232 | CGI:chr7:37447751-37449069 | UTR,promoter,exon,gene body | 1.99e-01 | 8.27e-02 | 2.42e+00 | 1.54e-02 | 1.91e-02 | 1.17e-01 |
| LUAD | cg01552551 | chr7:37450048 | CGI:chr7:37447751-37449069 | promoter | 7.79e-01 | 8.93e-01 | -2.54e+00 | 1.11e-02 | 1.45e-02 | -1.14e-01 |
| HNSC | cg01552551 | chr7:37450048 | CGI:chr7:37447751-37449069 | promoter | 7.01e-01 | 8.82e-01 | -2.46e+00 | 1.39e-02 | 1.69e-02 | -1.81e-01 |
| LUSC | cg06159352 | chr7:37448010 | CGI:chr7:37447751-37449069 | promoter,gene body | 1.91e-01 | 5.85e-02 | 2.28e+00 | 2.26e-02 | 2.63e-02 | 1.33e-01 |
| LUSC | cg01552551 | chr7:37450048 | CGI:chr7:37447751-37449069 | promoter | 7.70e-01 | 9.27e-01 | -2.36e+00 | 1.83e-02 | 2.22e-02 | -1.57e-01 |
| BLCA | cg00549566 | chr7:37448650 | CGI:chr7:37447751-37449069 | promoter,gene body | 2.64e-01 | 8.57e-02 | 2.98e+00 | 2.90e-03 | 5.27e-03 | 1.79e-01 |
| BLCA | cg15947096 | chr7:37449232 | CGI:chr7:37447751-37449069 | UTR,promoter,exon,gene body | 1.83e-01 | 8.07e-02 | 1.97e+00 | 4.94e-02 | 4.95e-02 | 1.02e-01 |
Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg06159352 | chr7:37448010 | CGI:chr7:37447751-37449069 | promoter,gene body | 2.53e-01 | 7.82e-02 | 6.36e+00 | 2.04e-10 | 5.23e-10 | 1.74e-01 |
| BRCA | cg00549566 | chr7:37448650 | CGI:chr7:37447751-37449069 | promoter,gene body | 1.89e-01 | 7.20e-02 | 6.03e+00 | 1.64e-09 | 3.92e-09 | 1.16e-01 |
| BRCA | cg11372090 | chr7:37449057 | CGI:chr7:37447751-37449069 | UTR,promoter,exon,gene body | 1.86e-01 | 8.43e-02 | 3.49e+00 | 4.84e-04 | 6.64e-04 | 1.02e-01 |
| BRCA | cg17350006 | chr7:37449255 | CGI:chr7:37447751-37449069 | promoter | 1.91e-01 | 7.66e-02 | 8.21e+00 | 2.17e-16 | 8.80e-16 | 1.14e-01 |
| BRCA | cg04136149 | chr7:37449333 | CGI:chr7:37447751-37449069 | promoter | 2.58e-01 | 9.77e-02 | 6.89e+00 | 5.59e-12 | 1.62e-11 | 1.60e-01 |
Top |
Exon skipping events with PSI in TCGA for ELMO1 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
Landscape of exon skipping events across multiple cancer types. |
Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
Top |
RNA A-to-I editing events in TCGA for ELMO1 |
| ∗Please access CAeditome for RNA editing annotation. |
Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
Top |
Sex-biased TF-Gene network for ELMO1 |
TFs related to ELMO1.∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| MESO | ATOH7 | ELMO1 | 5.06e+00 | 9.84e-01 | 3.94e+00 | 1.33e-02 | Male-biased |
| MESO | BATF | ELMO1 | 4.11e+00 | 9.83e-01 | 2.67e+00 | 4.41e-03 | Male-biased |
| MESO | BHLHE22 | ELMO1 | 4.92e+00 | 9.89e-01 | 3.60e+00 | 7.15e-03 | Male-biased |
| MESO | FOXA2 | ELMO1 | 4.12e+00 | 9.87e-01 | 2.25e+00 | 9.50e-04 | Male-biased |
| MESO | FOXA3 | ELMO1 | 3.93e+00 | 9.83e-01 | 1.90e+00 | 5.36e-04 | Male-biased |
| MESO | FOXB1 | ELMO1 | 3.90e+00 | 9.83e-01 | 1.95e+00 | 7.01e-04 | Male-biased |
| MESO | FOXC1 | ELMO1 | 3.99e+00 | 9.82e-01 | 2.42e+00 | 2.80e-03 | Male-biased |
| MESO | FOXD3 | ELMO1 | 3.85e+00 | 9.81e-01 | 1.88e+00 | 6.49e-04 | Male-biased |
| MESO | FOXF1 | ELMO1 | 4.03e+00 | 9.85e-01 | 2.28e+00 | 1.43e-03 | Male-biased |
| MESO | FOXP1 | ELMO1 | 4.36e+00 | 9.87e-01 | 2.95e+00 | 5.08e-03 | Male-biased |
| MESO | GSX1 | ELMO1 | 4.74e+00 | 9.84e-01 | 3.58e+00 | 1.15e-02 | Male-biased |
| MESO | IRX1 | ELMO1 | 4.47e+00 | 9.80e-01 | 3.33e+00 | 1.24e-02 | Male-biased |
| MESO | IRX3 | ELMO1 | 4.64e+00 | 9.86e-01 | 3.37e+00 | 8.19e-03 | Male-biased |
| MESO | LHX3 | ELMO1 | 3.97e+00 | 9.83e-01 | 2.32e+00 | 2.09e-03 | Male-biased |
| MESO | MEIS1 | ELMO1 | 4.28e+00 | 9.83e-01 | 2.99e+00 | 7.41e-03 | Male-biased |
| MESO | MEOX1 | ELMO1 | 5.16e+00 | 9.82e-01 | 4.08e+00 | 1.52e-02 | Male-biased |
| MESO | MESP2 | ELMO1 | 5.00e+00 | 9.84e-01 | 3.86e+00 | 1.25e-02 | Male-biased |
| MESO | MYF6 | ELMO1 | 4.60e+00 | 9.83e-01 | 3.43e+00 | 1.11e-02 | Male-biased |
| MESO | NANOG | ELMO1 | 3.92e+00 | 9.82e-01 | 2.16e+00 | 1.42e-03 | Male-biased |
| MESO | NEUROG1 | ELMO1 | 5.30e+00 | 9.83e-01 | 4.20e+00 | 1.46e-02 | Male-biased |
| MESO | NKX3-1 | ELMO1 | 4.18e+00 | 9.87e-01 | 2.52e+00 | 2.04e-03 | Male-biased |
| MESO | OLIG1 | ELMO1 | 5.12e+00 | 9.87e-01 | 3.90e+00 | 1.00e-02 | Male-biased |
| MESO | OLIG2 | ELMO1 | 5.86e+00 | 9.86e-01 | 4.71e+00 | 1.26e-02 | Male-biased |
| MESO | POU4F1 | ELMO1 | 4.16e+00 | 9.87e-01 | 2.43e+00 | 1.61e-03 | Male-biased |
| MESO | POU5F1 | ELMO1 | 4.10e+00 | 9.84e-01 | 2.62e+00 | 3.80e-03 | Male-biased |
| MESO | SOX14 | ELMO1 | 4.33e+00 | 9.88e-01 | 2.84e+00 | 3.70e-03 | Male-biased |
| MESO | SOX15 | ELMO1 | 4.30e+00 | 9.88e-01 | 2.73e+00 | 2.91e-03 | Male-biased |
| MESO | SOX18 | ELMO1 | 4.23e+00 | 9.87e-01 | 2.68e+00 | 3.03e-03 | Male-biased |
| MESO | SRF | ELMO1 | 4.54e+00 | 9.86e-01 | 3.25e+00 | 7.62e-03 | Male-biased |
| MESO | ZNF525 | ELMO1 | 4.17e+00 | 9.82e-01 | 2.84e+00 | 6.34e-03 | Male-biased |
| READ | BHLHE22 | ELMO1 | 3.91e+00 | 1.36e-02 | 4.67e+00 | 9.81e-01 | Female-biased |
| READ | FOXA2 | ELMO1 | 2.78e+00 | 2.00e-03 | 4.02e+00 | 9.81e-01 | Female-biased |
| READ | FOXP1 | ELMO1 | 3.45e+00 | 8.59e-03 | 4.31e+00 | 9.81e-01 | Female-biased |
| READ | IRX3 | ELMO1 | 3.65e+00 | 1.11e-02 | 4.45e+00 | 9.81e-01 | Female-biased |
| READ | NKX3-1 | ELMO1 | 2.87e+00 | 1.59e-03 | 4.18e+00 | 9.86e-01 | Female-biased |
| READ | POU5F1 | ELMO1 | 2.90e+00 | 3.15e-03 | 4.02e+00 | 9.80e-01 | Female-biased |
| READ | SOX15 | ELMO1 | 3.09e+00 | 4.74e-03 | 4.10e+00 | 9.81e-01 | Female-biased |
| READ | SOX18 | ELMO1 | 3.08e+00 | 3.69e-03 | 4.16e+00 | 9.83e-01 | Female-biased |
ELMO1 related gene.∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
Top |
Sex-biased RBP-ES network for ELMO1 |
RBPs related to ES in ELMO1.∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| STAD | Fusip1 | exon_skip_474737 | 6.53e+00 | 1.06e-03 | 7.13e+00 | 9.87e-01 | Female-biased |
| PCPG | RBM24 | exon_skip_474748 | 1.06e+01 | 9.90e-01 | 1.03e+01 | 8.70e-03 | Male-biased |
| GBM | RBM24 | exon_skip_474748 | 1.03e+01 | 1.45e-02 | 1.07e+01 | 9.84e-01 | Female-biased |
| PAAD | Fusip1 | exon_skip_474737 | 6.83e+00 | 2.60e-03 | 7.25e+00 | 9.85e-01 | Female-biased |
| PAAD | PCBP1 | exon_skip_474737 | 7.32e+00 | 3.66e-03 | 7.70e+00 | 9.87e-01 | Female-biased |
ELMO1 related ES.∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
Top |
Sex-biased CeRNA regulation of gene |
Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
Top |
Sex-biased eQTL regulation of gene |
Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs2074795 | chr7:43788172:C:T | - | 0.429616699869058 | 0.0100815172148036 | GBM | Female-baised eQTL |
| rs57250078 | chr7:30401872:C:T | - | 0.271663890859188 | 0.0205942441500157 | GBM | Female-baised eQTL |
| rs2893341 | chr7:29579709:G:T | - | -0.346079502470167 | 0.0387230910481997 | GBM | Female-baised eQTL |
| rs4722934 | chr7:29586629:C:G | - | -0.346079502470167 | 0.0387230910481997 | GBM | Female-baised eQTL |
| rs1420116 | chr7:29588818:T:C | - | -0.346079502470167 | 0.0387230910481997 | GBM | Female-baised eQTL |
| rs6968899 | chr7:29578211:A:G | - | -0.345982348139876 | 0.0392637724589543 | GBM | Female-baised eQTL |
| rs11767548 | chr7:40898013:G:C | - | 0.210501050041405 | 0.0044991020390376 | LIHC | Female-baised eQTL |
| rs79588461 | chr7:37338767:G:A | gene | 0.232091093950792 | 0.00130649884295953 | BLCA | Female-baised eQTL |
| rs73092824 | chr7:43306395:A:G | - | 0.165406839435088 | 0.00378792161334121 | BLCA | Female-baised eQTL |
| rs28645963 | chr7:37347406:C:G | gene | 0.215286927711454 | 0.00437860537228865 | BLCA | Female-baised eQTL |
| rs79712423 | chr7:37762239:A:G | - | 0.137950578097702 | 0.00658114602176768 | BLCA | Female-baised eQTL |
| rs12532855 | chr7:43306972:C:T | - | 0.15231200875909 | 0.00856869704031673 | BLCA | Female-baised eQTL |
| rs28436641 | chr7:37363430:C:T | gene | 0.18479753906253 | 0.00921943253919801 | BLCA | Female-baised eQTL |
| rs12532870 | chr7:43307079:C:A | - | 0.157952641552987 | 0.0108226010442647 | BLCA | Female-baised eQTL |
| rs2709114 | chr7:37751293:A:G | - | -0.126888144123666 | 0.0202412871655991 | BLCA | Female-baised eQTL |
| rs113761053 | chr7:37794875:G:A | - | 0.126698556062825 | 0.0206831285400806 | BLCA | Female-baised eQTL |
| rs10488614 | chr7:37797093:A:G | - | 0.123941090996439 | 0.0258442914064391 | BLCA | Female-baised eQTL |
| rs112082842 | chr7:37720624:C:T | - | 0.123043577253723 | 0.0264030045487257 | BLCA | Female-baised eQTL |
| rs78899540 | chr7:27141473:A:C | - | 0.263391898359625 | 0.0268002180854403 | BLCA | Female-baised eQTL |
| rs4723641 | chr7:37353647:G:A | gene,exon,UTR | 0.186494671155054 | 0.0277731349105912 | BLCA | Female-baised eQTL |
| rs7801689 | chr7:36709936:T:C | - | -0.16419646353783 | 0.0318039716831787 | BLCA | Female-baised eQTL |
| rs77155718 | chr7:37731368:G:T | - | 0.11811841110796 | 0.0333077400705964 | BLCA | Female-baised eQTL |
| rs7801372 | chr7:43388441:T:C | - | 0.16108037960546 | 0.0341754882118155 | BLCA | Female-baised eQTL |
| rs29882 | chr7:40916429:A:G | - | 0.149181587955679 | 0.034628308782349 | BLCA | Female-baised eQTL |
| rs74481946 | chr7:40918234:G:A | - | 0.149181587955679 | 0.034628308782349 | BLCA | Female-baised eQTL |
| rs29875 | chr7:40907733:G:A | - | 0.148497536195125 | 0.0378461161602061 | BLCA | Female-baised eQTL |
| rs73100929 | chr7:41691871:A:G | - | 0.203790029073328 | 0.0386017575070054 | BLCA | Female-baised eQTL |
| rs17171172 | chr7:37833048:T:C | - | 0.119542983539802 | 0.0390061536393901 | BLCA | Female-baised eQTL |
| rs36014678 | chr7:43363715:G:A | - | 0.147101172624035 | 0.0416250041790177 | BLCA | Female-baised eQTL |
| rs34140960 | chr7:43363738:G:A | - | 0.147101172624035 | 0.0416250041790177 | BLCA | Female-baised eQTL |
| rs10238130 | chr7:37369176:G:A | gene | 0.154965568332458 | 0.0446113788639264 | BLCA | Female-baised eQTL |
| rs73337654 | chr7:37525864:A:G | - | 0.114468356988666 | 0.0456617023119194 | BLCA | Female-baised eQTL |
| rs73336891 | chr7:37832308:G:A | - | 0.117265419895131 | 0.0467742548437116 | BLCA | Female-baised eQTL |
| rs10951730 | chr7:43394271:G:A | - | 0.154328103437224 | 0.04895381971232 | BLCA | Female-baised eQTL |
| rs6955660 | chr7:45109811:T:C | - | 0.0836899508099477 | 0.00357218438608329 | LUAD | Female-baised eQTL |
| rs78992922 | chr7:27966422:C:T | - | 0.128118394162388 | 0.00830565790561057 | LUAD | Female-baised eQTL |
| rs2255749 | chr7:47368291:G:A | - | -0.0678452011349222 | 0.00871952869764766 | LUAD | Female-baised eQTL |
| rs2462628 | chr7:47373641:C:T | - | -0.0662894769709456 | 0.0101609876944337 | LUAD | Female-baised eQTL |
| rs7808433 | chr7:47375723:C:T | - | -0.0662894769709456 | 0.0101609876944337 | LUAD | Female-baised eQTL |
| rs73104171 | chr7:44966048:T:C | - | 0.177022658995022 | 0.0114707604722638 | LUAD | Female-baised eQTL |
| rs4724566 | chr7:47365568:C:T | - | -0.0661877813764925 | 0.0116223286640186 | LUAD | Female-baised eQTL |
| rs2949816 | chr7:47365855:C:T | - | -0.0661877813764925 | 0.0116223286640186 | LUAD | Female-baised eQTL |
| rs3757573 | chr7:45107965:G:A | - | 0.0707881020849969 | 0.0139387410473446 | LUAD | Female-baised eQTL |
| rs10279935 | chr7:47373259:C:T | - | -0.0643084380489102 | 0.0163789830755366 | LUAD | Female-baised eQTL |
| rs4724567 | chr7:47372892:A:G | - | -0.0641226164015835 | 0.0169245947897497 | LUAD | Female-baised eQTL |
| rs4724569 | chr7:47388499:A:T | - | 0.0762619319722236 | 0.0194758674646865 | LUAD | Female-baised eQTL |
| rs3757571 | chr7:45106985:G:A | - | 0.0696794470674802 | 0.0196919034655965 | LUAD | Female-baised eQTL |
| rs2141173 | chr7:41994802:G:A | - | 0.0660705642555001 | 0.022131614070765 | LUAD | Female-baised eQTL |
| rs1613636 | chr7:29674624:G:C | - | 0.0954567984534566 | 0.0239003759669081 | LUAD | Female-baised eQTL |
| rs10268231 | chr7:29699048:G:A | - | 0.108920292591442 | 0.0260398507113022 | LUAD | Female-baised eQTL |
| rs374726055 | chr7:29701389:T:C | - | 0.108920292591442 | 0.0260398507113022 | LUAD | Female-baised eQTL |
| rs10248598 | chr7:29696380:A:T | - | 0.105677887624552 | 0.0264374741897799 | LUAD | Female-baised eQTL |
| rs850116 | chr7:29683666:C:A | - | 0.104844215400011 | 0.0289851075180182 | LUAD | Female-baised eQTL |
| rs863728 | chr7:29684379:T:G | - | 0.104844215400011 | 0.0289851075180182 | LUAD | Female-baised eQTL |
| rs2462625 | chr7:47367614:G:A | - | -0.0610082515685656 | 0.0293070415120658 | LUAD | Female-baised eQTL |
| rs11772482 | chr7:41996024:T:C | - | 0.0644956550201478 | 0.0316779090576315 | LUAD | Female-baised eQTL |
| rs7802581 | chr7:46890536:A:G | - | 0.0811772103545491 | 0.032484116232064 | LUAD | Female-baised eQTL |
| rs73096845 | chr7:46894199:C:T | - | 0.0811772103545491 | 0.032484116232064 | LUAD | Female-baised eQTL |
| rs699511 | chr7:43771096:A:G | - | 0.0700316479150778 | 0.0327321789734404 | LUAD | Female-baised eQTL |
| rs699487 | chr7:42005702:G:A | - | 0.0654762982472368 | 0.0340443643957522 | LUAD | Female-baised eQTL |
| rs6967748 | chr7:45099564:T:C | - | 0.0662114404472241 | 0.0354658494590954 | LUAD | Female-baised eQTL |
| rs34177994 | chr7:47365775:A:T | - | -0.0635307622998797 | 0.0363109942878254 | LUAD | Female-baised eQTL |
| rs7796495 | chr7:43228158:G:A | - | 0.0655029011792028 | 0.0365255664868354 | LUAD | Female-baised eQTL |
| rs62457024 | chr7:29687953:A:G | - | 0.103936774322327 | 0.0374667487729533 | LUAD | Female-baised eQTL |
| rs2289375 | chr7:45104804:C:T | - | 0.0659717901915233 | 0.0377428447903946 | LUAD | Female-baised eQTL |
| rs2908760 | chr7:29688642:G:C | - | 0.10044087578448 | 0.0399939098983688 | LUAD | Female-baised eQTL |
| rs141196854 | chr7:29690655:C:T | - | 0.10044087578448 | 0.0399939098983688 | LUAD | Female-baised eQTL |
| rs10231414 | chr7:29692072:A:T | - | 0.10044087578448 | 0.0399939098983688 | LUAD | Female-baised eQTL |
| rs28447398 | chr7:29693811:T:C | - | 0.10044087578448 | 0.0399939098983688 | LUAD | Female-baised eQTL |
| rs6463084 | chr7:41995601:C:T | - | 0.0619809946200636 | 0.0406681312809199 | LUAD | Female-baised eQTL |
| rs10276796 | chr7:29701163:G:T | - | 0.102678592760699 | 0.040725962115189 | LUAD | Female-baised eQTL |
| rs7804783 | chr7:46878547:G:A | - | 0.0632095321312296 | 0.0408774820695227 | LUAD | Female-baised eQTL |
| rs4553 | chr7:45100293:G:A | - | 0.0653941704577064 | 0.0411112269683716 | LUAD | Female-baised eQTL |
| rs2470991 | chr7:47374574:A:C | - | -0.0612339151563789 | 0.0459364813494934 | LUAD | Female-baised eQTL |
| rs2107866 | chr7:46873642:T:C | - | 0.0778059476561706 | 0.046885267568976 | LUAD | Female-baised eQTL |
| rs112154253 | chr7:29690022:G:A | - | 0.0997613220291377 | 0.0473366107415663 | LUAD | Female-baised eQTL |
| rs7804695 | chr7:46878700:A:T | - | 0.0619024275007598 | 0.0476088880190824 | LUAD | Female-baised eQTL |
| rs9655465 | chr7:45098614:C:T | - | 0.0655086195424489 | 0.0482577970161435 | LUAD | Female-baised eQTL |
| rs6463083 | chr7:41995537:T:C | - | 0.0604528609464082 | 0.0492841334661204 | LUAD | Female-baised eQTL |
| rs10228576 | chr7:27857373:G:A | - | 0.12287405616103 | 0.0493761402415342 | LUAD | Female-baised eQTL |
Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs12154834 | chr7:32164683:C:T | - | 0.0555054628661329 | 0.0493098825282484 | LUSC | Male-baised eQTL |
| rs7780567 | chr7:31311252:C:G | - | 0.0572357986930493 | 0.0401958163345738 | KIRC | Male-baised eQTL |
| rs78079625 | chr7:39182194:T:G | - | 0.0682775563006011 | 0.0219803085797986 | BLCA | Male-baised eQTL |
| rs1035582 | chr7:37113147:G:A | gene | 0.0488827872172754 | 0.0230221126338973 | LUAD | Male-baised eQTL |
| rs10262830 | chr7:38271497:G:A | - | 0.0931831041145693 | 0.00851074828306776 | COAD | Male-baised eQTL |
| rs834602 | chr7:47406618:C:A | - | -0.0577070653170522 | 0.016288907476388 | COAD | Male-baised eQTL |
| rs62446212 | chr7:46906536:G:A | - | 0.0920043763077066 | 0.016422528285827 | COAD | Male-baised eQTL |
| rs1207914 | chr7:35161547:T:C | - | -0.0787394784727462 | 0.0165685567431179 | COAD | Male-baised eQTL |
| rs17594569 | chr7:47321322:G:T | - | 0.115807365959274 | 0.01925422741887 | COAD | Male-baised eQTL |
| rs336286 | chr7:35260201:T:A | - | 0.0804601724345417 | 0.0210606940656987 | COAD | Male-baised eQTL |
| rs1207908 | chr7:35151755:C:G | - | -0.0770119582438185 | 0.0211964310747195 | COAD | Male-baised eQTL |
| rs1207915 | chr7:35161554:G:A | - | -0.0770119582438185 | 0.0211964310747195 | COAD | Male-baised eQTL |
| rs1207916 | chr7:35161586:C:T | - | -0.0770119582438185 | 0.0211964310747195 | COAD | Male-baised eQTL |
| rs336282 | chr7:35249273:C:T | - | 0.0827205980796888 | 0.0259225510403047 | COAD | Male-baised eQTL |
| rs1207913 | chr7:35160863:A:G | - | -0.07242814497636 | 0.031001310921954 | COAD | Male-baised eQTL |
| rs1874232 | chr7:40152846:G:A | - | 0.0549790477864783 | 0.0369827291204229 | COAD | Male-baised eQTL |
| rs2158513 | chr7:35093235:C:T | - | 0.0705175636537133 | 0.0405262692584373 | COAD | Male-baised eQTL |
| rs200560656 | chr7:35097963:A:G | - | 0.0705175636537133 | 0.0405262692584373 | COAD | Male-baised eQTL |
| rs2214740 | chr7:46900466:T:C | - | 0.0814633291525724 | 0.0407496330403148 | COAD | Male-baised eQTL |
| rs10951880 | chr7:46902478:G:A | - | 0.0814633291525724 | 0.0407496330403148 | COAD | Male-baised eQTL |
| rs62446210 | chr7:46902967:G:T | - | 0.0814633291525724 | 0.0407496330403148 | COAD | Male-baised eQTL |
| rs4573162 | chr7:46900238:T:C | - | 0.082507071951116 | 0.0426411495600357 | COAD | Male-baised eQTL |
Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
Top |
Sex-biased eQTM regulation of gene |
Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg01579884 | chr7:36964785 | gene | -0.267993600933229 | 1.06820417745525e-06 | -0.5482077869767304 | 5.126455307099202e-09 | PAAD |
Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg22492271 | chr7:36919884 | gene | -0.270802189062416 | 1.32034647339557e-10 | -0.7375303183100543 | 6.077568878984579e-15 | PAAD |
| cg12570246 | chr7:36919751 | gene | -0.431324874497655 | 3.22316933808353e-10 | -0.7116196291548421 | 1.3761156121739875e-13 | PAAD |
| cg16798247 | chr7:36987081 | gene | -0.431324874497655 | 3.22316933808353e-10 | -0.7116196291548421 | 1.3761156121739875e-13 | PAAD |
| cg24799830 | chr7:36986285 | gene,exon,UTR | -0.204403085867186 | 1.05134550383044e-06 | -0.646307227537779 | 1.2510173511114887e-10 | PAAD |
| cg24110540 | chr7:37235016 | gene | 0.0790679179384178 | 3.43173391100959e-05 | 0.34413548011076056 | 1.6841664655296007e-08 | LUAD |
Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
Top |
Sex-biased sQTL regulation of gene |
Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
Top |
Sex-biased sQTM regulation of gene |
Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
Top |
Related disease information of ELMO1 |
Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000155849 | ELMO1 | C0011881 | Diabetic Nephropathy | 1 | CTD_human |
| ENSG00000155849 | ELMO1 | C0014518 | Toxic Epidermal Necrolysis | 1 | CTD_human |
| ENSG00000155849 | ELMO1 | C0017667 | Nodular glomerulosclerosis | 1 | CTD_human |
| ENSG00000155849 | ELMO1 | C0038325 | Stevens-Johnson Syndrome | 1 | CTD_human |
| ENSG00000155849 | ELMO1 | C0279628 | Adenocarcinoma Of Esophagus | 1 | CTD_human |
| ENSG00000155849 | ELMO1 | C1274933 | Drug-Induced Stevens Johnson Syndrome | 1 | CTD_human |
| ENSG00000155849 | ELMO1 | C3658301 | Mycoplasma-Induced Stevens-Johnson Syndrome | 1 | CTD_human |
| ENSG00000155849 | ELMO1 | C3658302 | Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum | 1 | CTD_human |