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Gene: ENSG00000152492 |
Summary for CCDC50 |
 Gene summary |
| Gene information | Ensembl ID | ENSG00000152492 | Gene symbol | CCDC50 |
| Gene name | coiled-coil domain containing 50 | |
| HGNC | 18111 | |
| Entrez ID | 152137 | |
| Gene type | protein_coding | |
| Synonyms | CCDC50|Ymer | |
| UniProtAcc | Q8IVM0 |
| Drugs associated with this gene(DrugBank). |
| Gene ID | Gene Symbol | Drug ID | Drug Name | Drug Type |
| Cancer therapeutic drugs associated with this gene(NCI). |
| Gene ID | Gene Name | Drug ID | Drug Name | Drug Type | Cancer |
Top |
Structure and expression level for CCDC50 |
| AS events and RNA A-to-I editing events of the gene in TCGA based on Genvode V22 structure. ∗For more information on exon skipping events please check the ExonskipDB database. ∗For more information on exon skipping events please check the CAeditome database. |
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| Landscape of gene expressions across multiple cancer types. |
 |
| Differentially expressed gene analysis between tumor male and tumor female samples. |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| Differentially expressed gene analysis between tumor male and normal male samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| CCDC50 | 3.00e+03 | -1.18e+00 | 1.85e-01 | -6.35e+00 | 2.13e-10 | 4.19e-09 | BLCA |
| Differentially expressed gene analysis between tumor female and normal female samples. |
 |
| Coding Name | Base Mean | log2FoldChange | lfcSE | Stat | P value | P.adjust Value | Cancer Type |
| CCDC50 | 2.74e+03 | -1.02e+00 | 1.16e-01 | -8.75e+00 | 2.22e-18 | 2.35e-17 | LUAD |
| CCDC50 | 4.26e+03 | -1.29e+00 | 5.17e-02 | -2.50e+01 | 9.68e-138 | 8.35e-136 | BRCA |
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Sex-biased somatic mutation for CCDC50 |
| ∗For more information on exon skipping events please check the ExonskipDB database. |
| Gene ID | Cancer Type | Hugo Symbol | Male | Female | pval | or | ci.up | ci.low | adjPval |
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DNA methylation with beta values for CCDC50 |
| Landscape of DNA methylation across multiple cancer types. |
 |
| Differentially expressed CpG sites between male tumor and female tumor patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| ACC | cg06694446 | chr3:191330964 | CGI:chr3:191329159-191329921 | promoter,gene body | 3.99e-01 | 5.33e-01 | -2.55e+00 | 1.08e-02 | 2.65e-02 | -1.35e-01 |
| CHOL | cg19066520 | chr3:191328758 | CGI:chr3:191329159-191329921 | promoter | 8.16e-01 | 6.61e-01 | 2.45e+00 | 1.42e-02 | 2.68e-02 | 1.55e-01 |
| Differentially expressed CpG sites between male tumor and male normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| KIRC | cg13506158 | chr3:191330588 | CGI:chr3:191329159-191329921 | promoter,gene body | 2.79e-01 | 1.51e-01 | 5.32e+00 | 1.06e-07 | 5.23e-07 | 1.28e-01 |
| HNSC | cg19066520 | chr3:191328758 | CGI:chr3:191329159-191329921 | promoter | 7.22e-01 | 8.78e-01 | -2.21e+00 | 2.71e-02 | 2.98e-02 | -1.56e-01 |
| LUSC | cg06694446 | chr3:191330964 | CGI:chr3:191329159-191329921 | promoter,gene body | 5.35e-01 | 3.86e-01 | 2.78e+00 | 5.45e-03 | 8.70e-03 | 1.49e-01 |
| COAD | cg13506158 | chr3:191330588 | CGI:chr3:191329159-191329921 | promoter,gene body | 3.56e-01 | 2.47e-01 | 2.98e+00 | 2.93e-03 | 5.37e-03 | 1.09e-01 |
| COAD | cg06694446 | chr3:191330964 | CGI:chr3:191329159-191329921 | promoter,gene body | 5.49e-01 | 4.46e-01 | 2.46e+00 | 1.38e-02 | 1.85e-02 | 1.03e-01 |
| ESCA | cg13506158 | chr3:191330588 | CGI:chr3:191329159-191329921 | promoter,gene body | 3.26e-01 | 2.14e-01 | 2.18e+00 | 2.90e-02 | 4.34e-02 | 1.12e-01 |
| Differentially expressed CpG sites between female tumor and female normal patients. |
| Cancer Type | CpG Site | Position | CpG Island | Position to Gene | ave1 | ave2 | wilcoxon.w | wilcoxon.p | padj | dBeta |
| BRCA | cg13506158 | chr3:191330588 | CGI:chr3:191329159-191329921 | promoter,gene body | 4.23e-01 | 2.23e-01 | 1.11e+01 | 9.78e-29 | 1.23e-27 | 2.00e-01 |
| BRCA | cg27269488 | chr3:191330622 | CGI:chr3:191329159-191329921 | promoter,gene body | 2.57e-01 | 1.34e-01 | 8.68e+00 | 4.01e-18 | 1.86e-17 | 1.23e-01 |
| BRCA | cg00591949 | chr3:191330650 | CGI:chr3:191329159-191329921 | promoter,gene body | 3.81e-01 | 2.59e-01 | 7.91e+00 | 2.62e-15 | 9.78e-15 | 1.21e-01 |
| BRCA | cg06694446 | chr3:191330964 | CGI:chr3:191329159-191329921 | promoter,gene body | 6.32e-01 | 3.48e-01 | 1.31e+01 | 2.57e-39 | 1.70e-37 | 2.84e-01 |
| LUAD | cg14855367 | chr3:191330519 | CGI:chr3:191329159-191329921 | promoter,gene body | 4.85e-01 | 2.49e-01 | 2.30e+00 | 2.17e-02 | 2.74e-02 | 2.36e-01 |
| LUAD | cg00591949 | chr3:191330650 | CGI:chr3:191329159-191329921 | promoter,gene body | 5.10e-01 | 3.51e-01 | 3.39e+00 | 6.97e-04 | 2.53e-03 | 1.59e-01 |
| HNSC | cg14855367 | chr3:191330519 | CGI:chr3:191329159-191329921 | promoter,gene body | 3.12e-01 | 1.80e-01 | 2.53e+00 | 1.13e-02 | 1.99e-02 | 1.32e-01 |
| HNSC | cg13506158 | chr3:191330588 | CGI:chr3:191329159-191329921 | promoter,gene body | 3.64e-01 | 2.36e-01 | 2.41e+00 | 1.60e-02 | 2.42e-02 | 1.27e-01 |
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Exon skipping events with PSI in TCGA for CCDC50 |
| ∗Please access ExonSkipDB for exon skipping annotation. |
| Landscape of exon skipping events across multiple cancer types. |
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| Differentially expressed exon skipping events between male tumor and female tumor patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| KICH | exon_skip_380574 | 6.69e-01 | 5.48e-01 | 2.15e+00 | 3.13e-02 | 4.99e-02 | 1.21e-01 |
| Differentially expressed exon skipping events between male tumor and male normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| BLCA | exon_skip_380574 | 2.09e-01 | 9.71e-02 | 2.57e+00 | 1.02e-02 | 2.12e-02 | 1.12e-01 |
| ESCA | exon_skip_380574 | 2.29e-01 | 4.48e-01 | -2.29e+00 | 2.23e-02 | 3.42e-02 | -2.19e-01 |
| Differentially expressed exon skipping events between female tumor and female normal patients. |
| Cancer Type | Exon Skipping | ave.female_T | ave.female_N | wilcoxon.w | wilcoxon.p | padj | dPSI |
| BRCA | exon_skip_380574 | 2.66e-01 | 1.59e-01 | 6.81e+00 | 9.78e-12 | 9.54e-11 | 1.07e-01 |
| COAD | exon_skip_380574 | 3.88e-01 | 5.23e-01 | -3.71e+00 | 2.05e-04 | 1.02e-03 | -1.36e-01 |
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RNA A-to-I editing events in TCGA for CCDC50 |
| ∗Please access CAeditome for RNA editing annotation. |
| Differentially expressed RNA editing events between male tumor and female tumor patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between male tumor and male normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Differentially expressed RNA editing events between female tumor and female normal patients. |
| Cancer Type | Transcript | Editing | ave.male_T | ave.female_T | wilcoxon.w | wilcoxon.p | p_adj | dFre |
| Protein coding RNA editing(s). |
| Editing Position | Variant Type | Gene Symbol | Transcript ID | NTchange | AAchange |
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Sex-biased TF-Gene network for CCDC50 |
| TFs related to CCDC50. ∗The female-biased TF-gene edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased TF-gene edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | TF | Target Gene | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| BLCA | CDX2 | CCDC50 | 3.09e+00 | 2.96e-03 | 4.24e+00 | 9.86e-01 | Female-biased |
| BLCA | DMRT3 | CCDC50 | 3.85e+00 | 5.38e-03 | 4.86e+00 | 9.90e-01 | Female-biased |
| BLCA | DMRTA1 | CCDC50 | 3.63e+00 | 4.92e-03 | 4.66e+00 | 9.89e-01 | Female-biased |
| BLCA | DMRTA2 | CCDC50 | 3.69e+00 | 4.96e-03 | 4.72e+00 | 9.90e-01 | Female-biased |
| BLCA | EN1 | CCDC50 | 3.99e+00 | 9.19e-03 | 4.87e+00 | 9.87e-01 | Female-biased |
| BLCA | EVX2 | CCDC50 | 3.31e+00 | 7.45e-03 | 4.23e+00 | 9.81e-01 | Female-biased |
| BLCA | HOXC10 | CCDC50 | 3.34e+00 | 4.14e-03 | 4.41e+00 | 9.87e-01 | Female-biased |
| BLCA | SOX4 | CCDC50 | 3.27e+00 | 6.73e-03 | 4.21e+00 | 9.81e-01 | Female-biased |
| BLCA | STAT2 | CCDC50 | 2.86e+00 | 2.78e-03 | 4.02e+00 | 9.81e-01 | Female-biased |
| BLCA | ZIM3 | CCDC50 | 3.08e+00 | 3.19e-03 | 4.21e+00 | 9.85e-01 | Female-biased |
| BLCA | ZNF300 | CCDC50 | 3.93e+00 | 9.81e-01 | 2.25e+00 | 4.91e-04 | Male-biased |
| BLCA | ZNF37A | CCDC50 | 4.11e+00 | 9.86e-01 | 2.65e+00 | 1.05e-03 | Male-biased |
| BLCA | ZNF460 | CCDC50 | 4.03e+00 | 9.83e-01 | 2.72e+00 | 1.71e-03 | Male-biased |
| BLCA | ZNF468 | CCDC50 | 4.02e+00 | 9.83e-01 | 2.64e+00 | 1.37e-03 | Male-biased |
| BLCA | ZNF534 | CCDC50 | 3.99e+00 | 9.82e-01 | 2.68e+00 | 1.71e-03 | Male-biased |
| BLCA | ZNF570 | CCDC50 | 2.74e+00 | 7.24e-04 | 4.26e+00 | 9.88e-01 | Female-biased |
| BLCA | ZNF682 | CCDC50 | 3.91e+00 | 9.80e-01 | 2.27e+00 | 5.44e-04 | Male-biased |
| BLCA | ZNF740 | CCDC50 | 3.98e+00 | 9.82e-01 | 2.60e+00 | 1.35e-03 | Male-biased |
| BLCA | ZNF816 | CCDC50 | 4.09e+00 | 9.86e-01 | 2.43e+00 | 5.13e-04 | Male-biased |
| BLCA | ZNF879 | CCDC50 | 2.36e+00 | 1.50e-04 | 4.29e+00 | 9.89e-01 | Female-biased |
| GBM | CDX2 | CCDC50 | 4.57e+00 | 9.86e-01 | 3.42e+00 | 8.42e-03 | Male-biased |
| GBM | DMRT3 | CCDC50 | 5.29e+00 | 9.86e-01 | 4.24e+00 | 1.19e-02 | Male-biased |
| GBM | DMRTA1 | CCDC50 | 5.24e+00 | 9.90e-01 | 4.05e+00 | 7.68e-03 | Male-biased |
| GBM | DMRTA2 | CCDC50 | 5.33e+00 | 9.90e-01 | 4.14e+00 | 7.85e-03 | Male-biased |
| GBM | EN1 | CCDC50 | 5.39e+00 | 9.88e-01 | 4.29e+00 | 1.01e-02 | Male-biased |
| GBM | HOXC10 | CCDC50 | 4.77e+00 | 9.87e-01 | 3.64e+00 | 8.94e-03 | Male-biased |
| GBM | PBX2 | CCDC50 | 4.73e+00 | 9.80e-01 | 3.77e+00 | 1.52e-02 | Male-biased |
| GBM | SOX4 | CCDC50 | 4.53e+00 | 9.82e-01 | 3.49e+00 | 1.15e-02 | Male-biased |
| GBM | ZNF570 | CCDC50 | 4.53e+00 | 9.88e-01 | 3.25e+00 | 5.55e-03 | Male-biased |
| GBM | ZNF879 | CCDC50 | 4.55e+00 | 9.90e-01 | 3.18e+00 | 4.25e-03 | Male-biased |
| LGG | ZNF496 | CCDC50 | 4.08e+00 | 9.87e-03 | 4.58e+00 | 9.83e-01 | Female-biased |
| CCDC50 related gene. ∗Only the gene encode TF might with this result. ∗For more information please check Sex-biased TF-Coding gene network. |
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Sex-biased RBP-ES network for CCDC50 |
| RBPs related to ES in CCDC50. ∗The female-biased RBP-ES edges were identified if Female_Edge_threshold>0.98 and Male_Edge_threshold<=0.98. ∗The male-biased RBP-ES edges were identified if Male_Edge_threshold>0.98 and Female_Edge_threshold<=0.98. |
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| Cancer Type | RBP | Target ES | Male Edge Score | Male Edge Threshold | Female Edge Score | Female Edge Threshold | Type |
| LIHC | SAMD4A | exon_skip_380584 | 6.78e+00 | 9.83e-01 | 5.99e+00 | 6.80e-04 | Male-biased |
| LGG | SAMD4A | exon_skip_380584 | 5.95e+00 | 6.15e-04 | 6.57e+00 | 9.82e-01 | Female-biased |
| BLCA | SAMD4A | exon_skip_380584 | 6.94e+00 | 9.85e-01 | 6.23e+00 | 5.92e-04 | Male-biased |
| CCDC50 related ES. ∗Only the gene encode RBP might with this result. ∗For more information please check Sex-biased RBP-ES network in cancer. |
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Sex-biased CeRNA regulation of gene |
| Sex-biased CeRNA regulation of gene. |
| Gene ID | ceRNA(lncRNA-miRNA-mRNA) | Group | Cancer Type |
| ENSG00000152492 | AL122035.2,hsa-mir-203a,CCDC50 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000152492 | LOH12CR2,hsa-mir-203a,CCDC50 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000152492 | LINC01140,hsa-mir-203a,CCDC50 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000152492 | AC022364.1,hsa-mir-203a,CCDC50 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000152492 | AL391807.1,hsa-mir-203a,CCDC50 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000152492 | GNG12-AS1,hsa-mir-203a,CCDC50 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000152492 | LINC01094,hsa-mir-203a,CCDC50 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000152492 | AL590004.3,hsa-mir-203a,CCDC50 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000152492 | AC005330.1,hsa-mir-203a,CCDC50 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000152492 | LINC01278,hsa-mir-665,CCDC50 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000152492 | AC108676.1,hsa-mir-665,CCDC50 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000152492 | CACNA1C-AS1,hsa-mir-665,CCDC50 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000152492 | AC116447.1,hsa-mir-665,CCDC50 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000152492 | AC104794.3,hsa-mir-665,CCDC50 | Male-specific ceRNA | TCGA-BLCA |
| ENSG00000152492 | ENTPD1-AS1,hsa-mir-665,CCDC50 | Male-specific ceRNA | TCGA-BLCA |
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Sex-biased eQTL regulation of gene |
| Sex-biased eQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| eQTL | Description |
| Male-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs2276711 | chr3:196327133:G:A | - | 0.194061226907452 | 0.010548687843792 | GBM | Female-baised eQTL |
| rs4687041 | chr3:189359808:A:C | - | 0.327827348527073 | 0.0230977326476018 | GBM | Female-baised eQTL |
| rs36072535 | chr3:189360774:G:T | - | 0.327827348527073 | 0.0230977326476018 | GBM | Female-baised eQTL |
| rs344958 | chr3:188176107:G:T | - | 0.275778274397682 | 0.0164840873603508 | BLCA | Female-baised eQTL |
| rs113716741 | chr3:185889816:A:G | - | 0.106474242946211 | 0.0497084288687648 | BLCA | Female-baised eQTL |
| rs36051853 | chr3:185890087:T:C | - | 0.106474242946211 | 0.0497084288687648 | BLCA | Female-baised eQTL |
| rs80188220 | chr3:188000489:G:C | - | 0.144869753622359 | 0.00235013642355204 | LUAD | Female-baised eQTL |
| rs9846698 | chr3:184665004:C:T | - | 0.0570905044659898 | 0.012828876723401 | LUAD | Female-baised eQTL |
| rs9851637 | chr3:184665833:C:T | - | 0.056007959187901 | 0.0133162692039912 | LUAD | Female-baised eQTL |
| rs13098740 | chr3:187005362:A:G | - | -0.0536215715733957 | 0.0200723667080556 | LUAD | Female-baised eQTL |
| rs6788832 | chr3:187006431:A:G | - | -0.0536393490544629 | 0.0204685500589129 | LUAD | Female-baised eQTL |
| rs7617523 | chr3:187004662:T:G | - | -0.0527300074951806 | 0.0217764672718954 | LUAD | Female-baised eQTL |
| rs1027498 | chr3:188024865:G:A | - | -0.0505539960623289 | 0.0243098608012467 | LUAD | Female-baised eQTL |
| rs58503904 | chr3:195946123:C:T | - | 0.122588618497123 | 0.0431013854914343 | LUAD | Female-baised eQTL |
| rs111845588 | chr3:184422297:G:A | - | 0.0823707461686239 | 0.0444795107409587 | LUAD | Female-baised eQTL |
| rs74778113 | chr3:195942727:T:G | - | 0.118896476021572 | 0.0486340876791304 | LUAD | Female-baised eQTL |
| rs823039 | chr3:194981108:G:A | - | 0.130283655093016 | 0.0119385865779967 | COAD | Female-baised eQTL |
| rs13101138 | chr3:191961678:C:G | - | -0.0767339486453798 | 0.0259702443505362 | COAD | Female-baised eQTL |
| rs823026 | chr3:194971856:G:C | - | 0.131849190446777 | 0.0371745911562172 | COAD | Female-baised eQTL |
| rs823027 | chr3:194972066:A:G | - | 0.13167717349416 | 0.0434974469693248 | COAD | Female-baised eQTL |
| Female-specific eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Effect Score | FDR | Cancer Type | Biased Type |
| rs9840852 | chr3:182780472:G:A | - | 0.245127753600999 | 0.0231549797188095 | PCPG | Male-baised eQTL |
| rs3773855 | chr3:197141000:G:A | - | 0.0391044419816735 | 0.0426366636882935 | KIRC | Male-baised eQTL |
| rs74715659 | chr3:187972793:C:T | - | 0.0612993728710844 | 0.0487443931877121 | KIRC | Male-baised eQTL |
| rs111316404 | chr3:190114065:G:A | - | 0.157664765919419 | 4.64263308403954e-07 | COAD | Male-baised eQTL |
| rs77117144 | chr3:190099087:G:A | - | 0.147209867218416 | 1.98398289142711e-06 | COAD | Male-baised eQTL |
| rs76469721 | chr3:190099239:C:A | - | 0.147209867218416 | 1.98398289142711e-06 | COAD | Male-baised eQTL |
| rs76026488 | chr3:190099566:A:T | - | 0.147209867218416 | 1.98398289142711e-06 | COAD | Male-baised eQTL |
| rs112182850 | chr3:190100223:A:C | - | 0.147209867218416 | 1.98398289142711e-06 | COAD | Male-baised eQTL |
| rs112396952 | chr3:190100318:G:A | - | 0.147209867218416 | 1.98398289142711e-06 | COAD | Male-baised eQTL |
| rs79666261 | chr3:190100405:A:G | - | 0.147209867218416 | 1.98398289142711e-06 | COAD | Male-baised eQTL |
| rs76742324 | chr3:190100555:G:A | - | 0.147209867218416 | 1.98398289142711e-06 | COAD | Male-baised eQTL |
| rs76765753 | chr3:190101247:T:C | - | 0.147209867218416 | 1.98398289142711e-06 | COAD | Male-baised eQTL |
| rs77594297 | chr3:190102785:C:T | - | 0.147209867218416 | 1.98398289142711e-06 | COAD | Male-baised eQTL |
| rs16865070 | chr3:190105609:G:T | - | 0.14600373396307 | 2.66288684040265e-06 | COAD | Male-baised eQTL |
| rs28492997 | chr3:190107101:T:C | - | 0.14600373396307 | 2.66288684040265e-06 | COAD | Male-baised eQTL |
| rs7649797 | chr3:197536262:T:C | - | 0.113274132688951 | 4.40420471444335e-06 | COAD | Male-baised eQTL |
| rs7649784 | chr3:197536422:A:G | - | 0.113274132688951 | 4.40420471444335e-06 | COAD | Male-baised eQTL |
| rs7615878 | chr3:197536736:G:A | - | 0.111986615692697 | 6.66381334671634e-06 | COAD | Male-baised eQTL |
| rs2030572 | chr3:190104537:A:G | - | 0.128690097949604 | 2.40368779569276e-05 | COAD | Male-baised eQTL |
| rs73891806 | chr3:198036693:C:T | - | 0.126245059695639 | 6.51363554788223e-05 | COAD | Male-baised eQTL |
| rs13061303 | chr3:197526291:G:A | - | 0.0906587591544524 | 0.000440007775487195 | COAD | Male-baised eQTL |
| rs9881056 | chr3:197956719:T:A | - | 0.0693277432796057 | 0.000652146058910333 | COAD | Male-baised eQTL |
| rs9818493 | chr3:197956552:G:A | - | 0.0660864250947867 | 0.00119844866980047 | COAD | Male-baised eQTL |
| rs7618901 | chr3:195112673:A:G | - | 0.0755831087866296 | 0.00124446610054555 | COAD | Male-baised eQTL |
| rs9867148 | chr3:197944458:A:T | - | 0.0658087023367583 | 0.00136336945853519 | COAD | Male-baised eQTL |
| rs61215870 | chr3:197954624:C:T | - | 0.0655632562771201 | 0.0014012991820969 | COAD | Male-baised eQTL |
| rs9835340 | chr3:197949332:G:A | - | 0.0606399115023203 | 0.00283409183459364 | COAD | Male-baised eQTL |
| rs9820771 | chr3:197947264:G:A | - | 0.0598987584121533 | 0.00352365366808681 | COAD | Male-baised eQTL |
| rs6767234 | chr3:195116026:A:G | - | 0.0680801668414116 | 0.00355840737685308 | COAD | Male-baised eQTL |
| rs2688530 | chr3:195808595:T:C | - | -0.0626371270560168 | 0.00549814172632567 | COAD | Male-baised eQTL |
| rs4677807 | chr3:195115686:G:A | - | 0.0647932548204517 | 0.0058048992578947 | COAD | Male-baised eQTL |
| rs10937118 | chr3:183214057:A:G | - | -0.0466079048552143 | 0.00614054360174183 | COAD | Male-baised eQTL |
| rs9877500 | chr3:197957067:A:G | - | 0.0583653876779873 | 0.00619879293341599 | COAD | Male-baised eQTL |
| rs9882098 | chr3:197946617:T:C | - | 0.0571096219472296 | 0.00671717872204435 | COAD | Male-baised eQTL |
| rs939338 | chr3:183986280:G:A | - | -0.0476795298257275 | 0.0078872121215042 | COAD | Male-baised eQTL |
| rs9813570 | chr3:197942557:T:C | - | 0.0553200816257241 | 0.0079502377130877 | COAD | Male-baised eQTL |
| rs3749255 | chr3:197944156:C:T | - | 0.0553200816257241 | 0.0079502377130877 | COAD | Male-baised eQTL |
| rs76482311 | chr3:197918488:A:C | - | 0.0827203334319009 | 0.00921169953094206 | COAD | Male-baised eQTL |
| rs112686151 | chr3:197921222:G:A | - | 0.0827476525729425 | 0.00934296570047653 | COAD | Male-baised eQTL |
| rs112460661 | chr3:197928018:G:C | - | 0.0826114631656988 | 0.00937523415535473 | COAD | Male-baised eQTL |
| rs11718383 | chr3:191622097:G:A | - | 0.0707887963155157 | 0.0100277940392274 | COAD | Male-baised eQTL |
| rs6768307 | chr3:198001039:T:C | - | 0.054156801076184 | 0.0100730497383883 | COAD | Male-baised eQTL |
| rs7650562 | chr3:197942645:T:C | - | 0.0525121235422029 | 0.010280598405475 | COAD | Male-baised eQTL |
| rs7631404 | chr3:197946333:G:C | - | 0.0513081498601443 | 0.0118386598134748 | COAD | Male-baised eQTL |
| rs7618542 | chr3:197946335:T:C | - | 0.0513081498601443 | 0.0118386598134748 | COAD | Male-baised eQTL |
| rs9834734 | chr3:198019897:G:A | - | 0.0513841906646321 | 0.0119549782261873 | COAD | Male-baised eQTL |
| rs6768029 | chr3:198030882:T:C | - | 0.0513841906646321 | 0.0119549782261873 | COAD | Male-baised eQTL |
| rs7431003 | chr3:197962339:T:C | - | 0.0518277275316152 | 0.012854901588806 | COAD | Male-baised eQTL |
| rs6422711 | chr3:198023782:A:T | - | 0.0509239351581428 | 0.0133908218363303 | COAD | Male-baised eQTL |
| rs12631256 | chr3:198025447:T:C | - | 0.0509239351581428 | 0.0133908218363303 | COAD | Male-baised eQTL |
| rs79913146 | chr3:197919508:T:C | - | 0.0773671471653029 | 0.0136843263049565 | COAD | Male-baised eQTL |
| rs6763543 | chr3:198040075:G:A | - | 0.0498006764365397 | 0.0143337751345641 | COAD | Male-baised eQTL |
| rs13327370 | chr3:198017327:A:G | - | 0.0530761485389517 | 0.0153633705791733 | COAD | Male-baised eQTL |
| rs6605317 | chr3:198029337:T:A | - | 0.050042496674923 | 0.0157501257181801 | COAD | Male-baised eQTL |
| rs7651122 | chr3:197907151:T:C | - | 0.0504359518620057 | 0.0162792955505948 | COAD | Male-baised eQTL |
| rs7631002 | chr3:197950388:T:C | - | 0.0508063321317183 | 0.0163147167706061 | COAD | Male-baised eQTL |
| rs9808895 | chr3:197948086:A:C | - | 0.0496841965931624 | 0.0164074268297523 | COAD | Male-baised eQTL |
| rs78752796 | chr3:197992253:A:C | - | 0.107804350771646 | 0.0165049084511923 | COAD | Male-baised eQTL |
| rs6414503 | chr3:184044789:T:C | - | -0.0438058241656548 | 0.0182607750495128 | COAD | Male-baised eQTL |
| rs6605322 | chr3:197977629:T:A | - | 0.0494829380424884 | 0.018449684693243 | COAD | Male-baised eQTL |
| rs6803917 | chr3:197997747:T:C | - | 0.0489045171301495 | 0.0190103397408366 | COAD | Male-baised eQTL |
| rs7374380 | chr3:197980051:G:A | - | 0.0484072764812311 | 0.0190396037687798 | COAD | Male-baised eQTL |
| rs7427316 | chr3:197977263:C:G | - | 0.0483708574304766 | 0.0194799522970488 | COAD | Male-baised eQTL |
| rs7428537 | chr3:197977281:T:G | - | 0.0483708574304766 | 0.0194799522970488 | COAD | Male-baised eQTL |
| rs12630618 | chr3:198025315:A:G | - | 0.0483315511445222 | 0.0195296864443504 | COAD | Male-baised eQTL |
| rs12630644 | chr3:198025449:A:G | - | 0.0483315511445222 | 0.0195296864443504 | COAD | Male-baised eQTL |
| rs7431059 | chr3:197932605:T:C | - | 0.0488000289293554 | 0.020630184585268 | COAD | Male-baised eQTL |
| rs9846662 | chr3:197934762:T:G | - | 0.0487875365774805 | 0.0213151298038329 | COAD | Male-baised eQTL |
| rs7611969 | chr3:187382869:A:T | - | -0.0439626062404319 | 0.021773766020669 | COAD | Male-baised eQTL |
| rs6809462 | chr3:197915505:C:A | - | 0.0489172504878071 | 0.0223151601405631 | COAD | Male-baised eQTL |
| rs6773981 | chr3:197915024:A:T | - | 0.0481302921655987 | 0.0237393107195587 | COAD | Male-baised eQTL |
| rs6784201 | chr3:197917904:A:T | - | 0.0478834806973102 | 0.0246830382995522 | COAD | Male-baised eQTL |
| rs9817057 | chr3:197918346:T:C | - | 0.0478834806973102 | 0.0246830382995522 | COAD | Male-baised eQTL |
| rs9855189 | chr3:189313846:A:G | - | 0.0420543587384596 | 0.0252153310018488 | COAD | Male-baised eQTL |
| rs4686820 | chr3:186963484:G:A | - | -0.0593165258446142 | 0.0253722887979796 | COAD | Male-baised eQTL |
| rs55768822 | chr3:197924395:G:A | - | 0.0476418918798267 | 0.0257136560345913 | COAD | Male-baised eQTL |
| rs56999795 | chr3:197929014:T:C | - | 0.0476418918798267 | 0.0257136560345913 | COAD | Male-baised eQTL |
| rs112721339 | chr3:197918896:T:C | - | 0.0477055853497352 | 0.0259915269268794 | COAD | Male-baised eQTL |
| rs6782303 | chr3:197919365:T:C | - | 0.0475831905827625 | 0.0264054746719209 | COAD | Male-baised eQTL |
| rs9838593 | chr3:197922523:T:C | - | 0.0475831905827625 | 0.0264054746719209 | COAD | Male-baised eQTL |
| rs9682084 | chr3:197929848:A:G | - | 0.0475831905827625 | 0.0264054746719209 | COAD | Male-baised eQTL |
| rs7431213 | chr3:184044826:C:G | - | -0.0419682637150301 | 0.0267905519252635 | COAD | Male-baised eQTL |
| rs7638192 | chr3:193571788:C:T | - | 0.0473145149453802 | 0.0268859738017051 | COAD | Male-baised eQTL |
| rs9681778 | chr3:197967330:T:A | - | 0.0466208758065466 | 0.0288776281370523 | COAD | Male-baised eQTL |
| rs9869967 | chr3:193569621:G:A | - | 0.046907401998313 | 0.028916973913756 | COAD | Male-baised eQTL |
| rs13326186 | chr3:193570268:G:A | - | 0.046907401998313 | 0.028916973913756 | COAD | Male-baised eQTL |
| rs11708998 | chr3:184123926:C:G | - | 0.0592750044572066 | 0.0298866301592465 | COAD | Male-baised eQTL |
| rs6605315 | chr3:198011239:T:C | - | 0.046267658896658 | 0.0300914290862567 | COAD | Male-baised eQTL |
| rs6605323 | chr3:197978107:A:C | - | 0.0458557555888756 | 0.0301299034411928 | COAD | Male-baised eQTL |
| rs7643385 | chr3:197979884:G:A | - | 0.0458557555888756 | 0.0301299034411928 | COAD | Male-baised eQTL |
| rs9325415 | chr3:198000611:G:A | - | 0.0462150438153274 | 0.0303332227101549 | COAD | Male-baised eQTL |
| rs9854429 | chr3:194104960:A:G | - | -0.0400053743328116 | 0.0308338363035176 | COAD | Male-baised eQTL |
| rs6777369 | chr3:198008846:T:C | - | 0.0461011458930596 | 0.0309694565914705 | COAD | Male-baised eQTL |
| rs6763785 | chr3:194147874:T:G | - | 0.0584163504761032 | 0.0311093453007902 | COAD | Male-baised eQTL |
| rs7373977 | chr3:197989109:T:C | - | 0.046114281973939 | 0.0316503872124146 | COAD | Male-baised eQTL |
| rs6762187 | chr3:197968097:T:C | - | 0.0458496241842062 | 0.0316759951807611 | COAD | Male-baised eQTL |
| rs111487088 | chr3:198047758:C:T | - | 0.0994002659697468 | 0.0323908879940514 | COAD | Male-baised eQTL |
| rs11916456 | chr3:184122878:C:G | - | 0.0548043056430066 | 0.0327523978405611 | COAD | Male-baised eQTL |
| rs7430671 | chr3:184043876:G:C | - | -0.0408710925024058 | 0.0334384417091726 | COAD | Male-baised eQTL |
| rs6796988 | chr3:191309710:G:C | - | 0.107675638663601 | 0.0338585016073025 | COAD | Male-baised eQTL |
| rs9842232 | chr3:188362375:C:G | - | 0.0392562962045585 | 0.036126943360116 | COAD | Male-baised eQTL |
| rs62289742 | chr3:188152990:C:T | - | 0.0476992552897698 | 0.0364104084874913 | COAD | Male-baised eQTL |
| rs9814347 | chr3:186635071:G:C | - | 0.0411150292172605 | 0.036422703737338 | COAD | Male-baised eQTL |
| rs9827840 | chr3:195838956:T:G | - | 0.0419908260328353 | 0.0371176072258034 | COAD | Male-baised eQTL |
| rs6788413 | chr3:191136639:C:G | - | 0.0387638387299483 | 0.0384012134398566 | COAD | Male-baised eQTL |
| rs9855764 | chr3:196671566:G:C | - | -0.0435298421367145 | 0.0388392763406507 | COAD | Male-baised eQTL |
| rs11924174 | chr3:184122841:A:G | - | 0.0553905926633087 | 0.0415732776461542 | COAD | Male-baised eQTL |
| rs9861619 | chr3:191964067:G:A | - | 0.0780826666454263 | 0.0454653688420702 | COAD | Male-baised eQTL |
| rs9845625 | chr3:191931144:C:T | - | 0.0748069881628117 | 0.047851657757698 | COAD | Male-baised eQTL |
| Opposite sex-biased eQTL regulation. |
| SNP ID | SNP Info | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Sex-biased Gene in Cancer | Cancer Type |
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Sex-biased eQTM regulation of gene |
| Sex-biased eQTM regulation of gene (The figures only show the pairs with FDR<1e-5. For more information please check the below table). |
| eQTM | Description |
 | Gene ID: ENSG00000152492 |
| CpG Site: cg13506158 | |
| Position to Gene: gene,promoter | |
| Male Effect: - | |
| Female Effect: -0.0529044764464215 |
| Male-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| Female-specific eQTM regulation. |
| CpG Site | CpG Postion | Position to Gene | Effect Score | FDR | Cor.r | Cor.Pvalue | Cancer Type |
| cg13506158 | chr3:191330588 | gene,promoter | -0.0529044764464215 | 5.59988714075036e-05 | -0.31113857282821494 | 9.237973664267551e-07 | LGG |
| Opposite sex-biased eQTM regulation. |
| CpG Site | CpG Postion | CpG Island | Position to Gene | Male Effect | Male FDR | Female Effect | Female FDR | Male Cor | Male P-value | Female Cor | Female P-value | Sex-biased Coding Gene | Cancer Type |
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Sex-biased sQTL regulation of gene |
| Sex-biased sQTL regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTL | Description |
| Male-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_380574 | chr3:191375061:191375589 | In-frame | rs9877274 | chr3:190775313:A:G | Distant upstream | 0.0627179917235437 | 0.0225053935539 | KIRC | Female-baised sQTL |
| exon_skip_380574 | chr3:191375061:191375589 | In-frame | rs6790793 | chr3:191200274:A:T | Distant upstream | 0.137758997128501 | 0.00117747772855187 | LIHC | Female-baised sQTL |
| exon_skip_380574 | chr3:191375061:191375589 | In-frame | rs57448281 | chr3:191192103:G:T | Distant upstream | 0.134941442955045 | 0.00189474535221444 | LIHC | Female-baised sQTL |
| exon_skip_380574 | chr3:191375061:191375589 | In-frame | rs55866170 | chr3:191193112:C:T | Distant upstream | 0.134941442955045 | 0.00189474535221444 | LIHC | Female-baised sQTL |
| exon_skip_380574 | chr3:191375061:191375589 | In-frame | rs12152251 | chr3:191197219:T:C | Distant upstream | 0.134941442955045 | 0.00189474535221444 | LIHC | Female-baised sQTL |
| exon_skip_380574 | chr3:191375061:191375589 | In-frame | rs12152342 | chr3:191197532:A:G | Distant upstream | 0.134941442955045 | 0.00189474535221444 | LIHC | Female-baised sQTL |
| exon_skip_380574 | chr3:191375061:191375589 | In-frame | rs114517080 | chr3:191186405:G:A | Distant upstream | 0.134455090115519 | 0.00203254418973229 | LIHC | Female-baised sQTL |
| exon_skip_380574 | chr3:191375061:191375589 | In-frame | rs75672792 | chr3:191205880:A:G | Distant upstream | 0.134455090115519 | 0.00203254418973229 | LIHC | Female-baised sQTL |
| exon_skip_380574 | chr3:191375061:191375589 | In-frame | rs6807068 | chr3:191187610:G:A | Distant upstream | 0.1306194680098 | 0.00206612821765774 | LIHC | Female-baised sQTL |
| exon_skip_380574 | chr3:191375061:191375589 | In-frame | rs59107288 | chr3:191188708:G:A | Distant upstream | 0.1306194680098 | 0.00206612821765774 | LIHC | Female-baised sQTL |
| exon_skip_380574 | chr3:191375061:191375589 | In-frame | rs7612793 | chr3:191189560:G:A | Distant upstream | 0.1306194680098 | 0.00206612821765774 | LIHC | Female-baised sQTL |
| exon_skip_380574 | chr3:191375061:191375589 | In-frame | rs11928253 | chr3:191192169:C:T | Distant upstream | 0.1306194680098 | 0.00206612821765774 | LIHC | Female-baised sQTL |
| exon_skip_380574 | chr3:191375061:191375589 | In-frame | rs6776691 | chr3:191194167:T:C | Distant upstream | 0.1306194680098 | 0.00206612821765774 | LIHC | Female-baised sQTL |
| exon_skip_380574 | chr3:191375061:191375589 | In-frame | rs4566591 | chr3:191195102:C:A | Distant upstream | 0.1306194680098 | 0.00206612821765774 | LIHC | Female-baised sQTL |
| exon_skip_380574 | chr3:191375061:191375589 | In-frame | rs116154134 | chr3:191173091:G:A | Distant upstream | 0.126313011570595 | 0.00533783224661803 | LIHC | Female-baised sQTL |
| Female-specific sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Effect Score | FDR | Cancer Type | Biased Type |
| exon_skip_380574 | chr3:191375061:191375589 | In-frame | rs9847806 | chr3:192132262:C:T | Distant downstream | -0.0488701770726448 | 0.0161602530211409 | LUAD | Male-baised sQTL |
| exon_skip_380574 | chr3:191375061:191375589 | In-frame | rs9848441 | chr3:192132544:G:C | Distant downstream | -0.0454317602604405 | 0.0342480662114756 | LUAD | Male-baised sQTL |
| exon_skip_380574 | chr3:191375061:191375589 | In-frame | rs16865970 | chr3:190843227:T:G | Distant upstream | 0.082159051785837 | 0.00755406130628418 | KIRP | Male-baised sQTL |
| Opposite sex-biased sQTL regulation. |
| ES ID | Skipped Exon | ORF Anno | SNP ID | SNP Info | SNP Position to ES | Male Effect | Male FDR | Female Effect | Female FDR | Cancer Type |
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Sex-biased sQTM regulation of gene |
| Sex-biased sQTM regulation of gene (The figures only show the pairs with FDR <1e-5. For more information please check the below table). |
| sQTM | Description |
 | EX ID: exon_skip_380574 |
| CpG Site: cg00591949 | |
| Position to EX: Distant upstream | |
| Male Effect: -0.192643880097569 | |
| Female Effect: - |
| Male-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| exon_skip_380574 | chr3:191375061:191375589 | cg00591949 | chr3:191330650 | Distant upstream | -0.192643880097569 | 3.71920265041045e-05 | -0.33190375987661325 | 6.352152813606567e-07 | In-frame | LUAD |
| Female-specific sQTM regulation. |
| EX ID | Skipped Exon | CPG Site | CPG Position | Position to EX Events | Effect Score | FDR | Cor.r | Cor.Pvalue | ORF_anno | Cancer Type |
| Opposite sex-biased sQTM regulation. |
| EX ID | EX Info | Skipped Exon | CPG Site | CPG Position | CPG Island | Position to EX Events | Male Effect | Male FDR | Female Effect | Female FDR | Male Correlation | Male P-value | Female Correlation | Female P-value | ORF_anno | Cancer Type |
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Related disease information of CCDC50 |
| Diseases associated with this gene (DisGeNET). |
| Gene ID | Gene Symbol | Disease ID | Disease Name | Number of PMID | Source |
| ENSG00000152492 | CCDC50 | C1843895 | Deafness, Autosomal Dominant 44 | 1 | CTD_human |
